Trait: hypertensive disorder

Trait Information
Identifier MONDO_0005044
Description Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more. [MESH: D006973]
Trait categories
Cardiovascular disease
Other disease
Synonyms 8 synonyms
  • HTN
  • blood pressure, high
  • blood pressure, increased
  • high blood pressure
  • hypertensive disease
  • increased blood pressure
  • pressure, high blood
  • vascular hypertensive disorder
Child trait(s) 2 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "hypertensive disorder" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000706
(HC215)
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Hypertension hypertensive disorder 186,726
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000706/ScoringFiles/PGS000706.txt.gz - Check Terms/Licenses
PGS000957
(GBE_HC932)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Essential (primary hypertension) (time-to-event) essential hypertension 11,276
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000957/ScoringFiles/PGS000957.txt.gz
PGS000958
(GBE_HC273)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Essential hypertension essential hypertension 9,400
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000958/ScoringFiles/PGS000958.txt.gz
PGS001320
(GBE_HC215)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hypertension hypertensive disorder 13,791
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001320/ScoringFiles/PGS001320.txt.gz
PGS001838
(portability-PLR_401)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 52,487
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001838/ScoringFiles/PGS001838.txt.gz
PGS002047
(portability-ldpred2_401)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 918,325
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002047/ScoringFiles/PGS002047.txt.gz
PGS002296
(PRS2166_HT)
 PGP000326 |
Maj C et al. Front Cardiovasc Med (2022)
 Hypertension hypertensive disorder 2,166
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002296/ScoringFiles/PGS002296.txt.gz
PGS002335
(disease_HYPERTENSION_DIAGNOSED.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypertension hypertensive disorder 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002335/ScoringFiles/PGS002335.txt.gz
PGS002407
(disease_HYPERTENSION_DIAGNOSED.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypertension hypertensive disorder 6,693
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002407/ScoringFiles/PGS002407.txt.gz
PGS002456
(disease_HYPERTENSION_DIAGNOSED.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypertension hypertensive disorder 22,539
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002456/ScoringFiles/PGS002456.txt.gz
PGS002505
(disease_HYPERTENSION_DIAGNOSED.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypertension hypertensive disorder 115,656
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002505/ScoringFiles/PGS002505.txt.gz
PGS002554
(disease_HYPERTENSION_DIAGNOSED.P+T.1e-06)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypertension hypertensive disorder 1,715
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002554/ScoringFiles/PGS002554.txt.gz
PGS002603
(disease_HYPERTENSION_DIAGNOSED.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypertension hypertensive disorder 949
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002603/ScoringFiles/PGS002603.txt.gz
PGS002652
(disease_HYPERTENSION_DIAGNOSED.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypertension hypertensive disorder 385,766
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002652/ScoringFiles/PGS002652.txt.gz
PGS002701
(disease_HYPERTENSION_DIAGNOSED.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypertension hypertensive disorder 973,782
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002701/ScoringFiles/PGS002701.txt.gz
PGS002765
(SBP_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 1,077,894
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002765/ScoringFiles/PGS002765.txt.gz
PGS002777
(GTG_Hypertension_maxCT)
 PGP000365 |
Wong CK et al. PLoS One (2022)
 Incident hypertension hypertensive disorder 61,669
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002777/ScoringFiles/PGS002777.txt.gz - Check Terms/Licenses
PGS002778
(GTG_Hypertension_SCT)
 PGP000365 |
Wong CK et al. PLoS One (2022)
 Incident hypertension hypertensive disorder 309,759
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002778/ScoringFiles/PGS002778.txt.gz - Check Terms/Licenses
PGS002994
(ExPRSweb_Hypertension_20002-1065_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 724,579
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002994/ScoringFiles/PGS002994.txt.gz
PGS002995
(ExPRSweb_Hypertension_20002-1065_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 26,671
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002995/ScoringFiles/PGS002995.txt.gz
PGS002996
(ExPRSweb_Hypertension_20002-1065_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 25,909
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002996/ScoringFiles/PGS002996.txt.gz
PGS002997
(ExPRSweb_Hypertension_20002-1065_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 7,601,215
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002997/ScoringFiles/PGS002997.txt.gz
PGS002998
(ExPRSweb_Hypertension_20002-1065_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002998/ScoringFiles/PGS002998.txt.gz
PGS002999
(ExPRSweb_Hypertension_20002-1072_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 313,080
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002999/ScoringFiles/PGS002999.txt.gz
PGS003000
(ExPRSweb_Hypertension_20002-1072_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 83,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003000/ScoringFiles/PGS003000.txt.gz
PGS003001
(ExPRSweb_Hypertension_20002-1072_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 81,218
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003001/ScoringFiles/PGS003001.txt.gz
PGS003002
(ExPRSweb_Hypertension_20002-1072_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 7,601,215
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003002/ScoringFiles/PGS003002.txt.gz
PGS003003
(ExPRSweb_Hypertension_20002-1072_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 1,109,030
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003003/ScoringFiles/PGS003003.txt.gz
PGS003004
(ExPRSweb_Hypertension_finngen-R4-FG_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 4,943
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003004/ScoringFiles/PGS003004.txt.gz
PGS003005
(ExPRSweb_Hypertension_finngen-R4-FG_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 2,860
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003005/ScoringFiles/PGS003005.txt.gz
PGS003006
(ExPRSweb_Hypertension_finngen-R4-FG_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 5,212
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003006/ScoringFiles/PGS003006.txt.gz
PGS003007
(ExPRSweb_Hypertension_finngen-R4-FG_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 359
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003007/ScoringFiles/PGS003007.txt.gz
PGS003008
(ExPRSweb_Hypertension_finngen-R4-FG_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 12,076
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003008/ScoringFiles/PGS003008.txt.gz
PGS003009
(ExPRSweb_Hypertension_finngen-R4-I9_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 5,226
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003009/ScoringFiles/PGS003009.txt.gz
PGS003010
(ExPRSweb_Hypertension_finngen-R4-I9_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 1,894
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003010/ScoringFiles/PGS003010.txt.gz
PGS003011
(ExPRSweb_Hypertension_finngen-R4-I9_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 3,300
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003011/ScoringFiles/PGS003011.txt.gz
PGS003012
(ExPRSweb_Hypertension_finngen-R4-I9_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 361
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003012/ScoringFiles/PGS003012.txt.gz
PGS003013
(ExPRSweb_Hypertension_finngen-R4-I9_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 12,076
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003013/ScoringFiles/PGS003013.txt.gz
PGS003014
(ExPRSweb_Hypertension_I10_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 294,142
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003014/ScoringFiles/PGS003014.txt.gz
PGS003015
(ExPRSweb_Hypertension_I10_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 58,725
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003015/ScoringFiles/PGS003015.txt.gz
PGS003016
(ExPRSweb_Hypertension_I10_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 56,978
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003016/ScoringFiles/PGS003016.txt.gz
PGS003017
(ExPRSweb_Hypertension_I10_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 7,094,727
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003017/ScoringFiles/PGS003017.txt.gz
PGS003018
(ExPRSweb_Hypertension_I10_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 1,096,197
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003018/ScoringFiles/PGS003018.txt.gz
PGS003019
(ExPRSweb_Hypertension_finngen-R4-FG_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 6,731
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003019/ScoringFiles/PGS003019.txt.gz
PGS003020
(ExPRSweb_Hypertension_finngen-R4-FG_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 24
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003020/ScoringFiles/PGS003020.txt.gz
PGS003021
(ExPRSweb_Hypertension_finngen-R4-FG_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 24
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003021/ScoringFiles/PGS003021.txt.gz
PGS003022
(ExPRSweb_Hypertension_finngen-R4-FG_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 56
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003022/ScoringFiles/PGS003022.txt.gz
PGS003023
(ExPRSweb_Hypertension_finngen-R4-FG_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 12,097
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003023/ScoringFiles/PGS003023.txt.gz
PGS003024
(ExPRSweb_Hypertension_finngen-R4-I9_LASSOSUM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 7,123
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003024/ScoringFiles/PGS003024.txt.gz
PGS003025
(ExPRSweb_Hypertension_finngen-R4-I9_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003025/ScoringFiles/PGS003025.txt.gz
PGS003026
(ExPRSweb_Hypertension_finngen-R4-I9_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 9
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003026/ScoringFiles/PGS003026.txt.gz
PGS003027
(ExPRSweb_Hypertension_finngen-R4-I9_DBSLMM_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 59
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003027/ScoringFiles/PGS003027.txt.gz
PGS003028
(ExPRSweb_Hypertension_finngen-R4-I9_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertensive disorder 12,097
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003028/ScoringFiles/PGS003028.txt.gz
PGS003586
(PE)
 PGP000462 |
Honigberg MC et al. Nat Med (2023)
 Pre-eclampsia preeclampsia 1,087,033
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003586/ScoringFiles/PGS003586.txt.gz
PGS003587
(GH)
 PGP000462 |
Honigberg MC et al. Nat Med (2023)
 Gestational hypertension preeclampsia 1,087,916
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003587/ScoringFiles/PGS003587.txt.gz
PGS004191
(hyper_1)
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Hypertension hypertensive disorder 23,280
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004191/ScoringFiles/PGS004191.txt.gz
PGS004192
(hyper_2)
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Hypertension hypertensive disorder 9,430
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004192/ScoringFiles/PGS004192.txt.gz
PGS004193
(hyper_3)
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Hypertension hypertensive disorder 18,580
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004193/ScoringFiles/PGS004193.txt.gz
PGS004194
(hyper_4)
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Hypertension hypertensive disorder 14,063
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004194/ScoringFiles/PGS004194.txt.gz
PGS004195
(hyper_5)
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Hypertension hypertensive disorder 2,755
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004195/ScoringFiles/PGS004195.txt.gz
PGS004234
(HTN_PAN-UKBB)
 PGP000531 |
Kurniansyah N et al. Nat Commun (2022)
 Hypertension hypertensive disorder 234,228
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004234/ScoringFiles/PGS004234.txt.gz
PGS004236
(HTN_Unweighted_PRSsum)
 PGP000531 |
Kurniansyah N et al. Nat Commun (2022)
 Hypertension hypertensive disorder 398,805
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004236/ScoringFiles/PGS004236.txt.gz
PGS004455
(disease.Hypertension.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Hypertension hypertensive disorder 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004455/ScoringFiles/PGS004455.txt.gz
PGS004456
(disease.I10.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 I10 (Essential (primary) hypertension) essential hypertension 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004456/ScoringFiles/PGS004456.txt.gz
PGS004525
(meta.Hypertension.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Hypertension hypertensive disorder 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004525/ScoringFiles/PGS004525.txt.gz
PGS004526
(meta.I10.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 I10 (Essential (primary) hypertension) essential hypertension 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004526/ScoringFiles/PGS004526.txt.gz
PGS004593
(pe)
 PGP000574 |
Nurkkala J et al. J Hypertens (2022)
 Preeclampsia preeclampsia 1,102,059
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004593/ScoringFiles/PGS004593.txt.gz
PGS004785
(HTN_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Hypertension hypertensive disorder 1,170,615
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004785/ScoringFiles/PGS004785.txt.gz
PGS004786
(HTN_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Hypertension hypertensive disorder 6,622,611
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004786/ScoringFiles/PGS004786.txt.gz
PGS004787
(HTN_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Hypertension hypertensive disorder 5,191,115
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004787/ScoringFiles/PGS004787.txt.gz
PGS004788
(HTN_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Hypertension hypertensive disorder 6,622,611
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004788/ScoringFiles/PGS004788.txt.gz
PGS004934
(hypertension_snpnet_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Hypertension hypertensive disorder 15,056
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004934/ScoringFiles/PGS004934.txt.gz
PGS005144
(Hypertension (PRS-CS; EAS))
 PGP000704 |
Jung HU et al. Commun Biol (2025)
 Hypertension hypertensive disorder 908,466
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005144/ScoringFiles/PGS005144.txt.gz
PGS005153
(Hypertension (CT-SLEB; EAS+EUR))
 PGP000704 |
Jung HU et al. Commun Biol (2025)
 Hypertension hypertensive disorder 492,555
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005153/ScoringFiles/PGS005153.txt.gz
PGS019132
(TPMI_401.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Essential hypertension essential hypertension 41,812
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019132/ScoringFiles/PGS019132.txt.gz
PGS019133
(TPMI_401.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Essential hypertension essential hypertension 939,820
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019133/ScoringFiles/PGS019133.txt.gz
PGS019134
(TPMI_401.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Essential hypertension essential hypertension 131,984
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019134/ScoringFiles/PGS019134.txt.gz
PGS019135
(TPMI_401.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Essential hypertension essential hypertension 983,772
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019135/ScoringFiles/PGS019135.txt.gz
PGS019136
(TPMI_401.1_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Essential hypertension essential hypertension 1,071,467
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019136/ScoringFiles/PGS019136.txt.gz
PGS019137
(TPMI_401.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Essential hypertension essential hypertension 1,004,286
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019137/ScoringFiles/PGS019137.txt.gz
PGS019144
(TPMI_401.3_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other hypertensive complications hypertensive disorder 35,755
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019144/ScoringFiles/PGS019144.txt.gz
PGS019145
(TPMI_401.3_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other hypertensive complications hypertensive disorder 939,864
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019145/ScoringFiles/PGS019145.txt.gz
PGS019146
(TPMI_401.3_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other hypertensive complications hypertensive disorder 84,636
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019146/ScoringFiles/PGS019146.txt.gz
PGS019147
(TPMI_401.3_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other hypertensive complications hypertensive disorder 983,809
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019147/ScoringFiles/PGS019147.txt.gz
PGS019148
(TPMI_401.3_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Other hypertensive complications hypertensive disorder 442,448
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019148/ScoringFiles/PGS019148.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001598 PGS000706
(HC215)
 PSS000822|
European Ancestry|
87,413 individuals
 PGP000128 |
Sinnott-Armstrong N et al. Nat Genet (2021)
 Reported Trait: Hypertension — AUROC: 0.623 — Age, sex, PCs(1-10) —
PPM007609 PGS000957
(GBE_HC932)
 PSS004711|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE essential (primary hypertension) — AUROC: 0.71865 [0.70527, 0.73203] R²: 0.17042
Incremental AUROC (full-covars): -0.00133
PGS R2 (no covariates): 0.00389
PGS AUROC (no covariates): 0.53092 [0.51597, 0.54587]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007610 PGS000957
(GBE_HC932)
 PSS004712|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE essential (primary hypertension) — AUROC: 0.7519 [0.72118, 0.78262] R²: 0.18828
Incremental AUROC (full-covars): 0.01726
PGS R2 (no covariates): 0.02831
PGS AUROC (no covariates): 0.59059 [0.55566, 0.62552]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007611 PGS000957
(GBE_HC932)
 PSS004713|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE essential (primary hypertension) — AUROC: 0.74724 [0.74015, 0.75433] R²: 0.19436
Incremental AUROC (full-covars): 0.02015
PGS R2 (no covariates): 0.03223
PGS AUROC (no covariates): 0.60027 [0.59183, 0.6087]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007612 PGS000957
(GBE_HC932)
 PSS004714|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE essential (primary hypertension) — AUROC: 0.73072 [0.71892, 0.74253] R²: 0.19598
Incremental AUROC (full-covars): 0.00857
PGS R2 (no covariates): 0.01913
PGS AUROC (no covariates): 0.56924 [0.55569, 0.58279]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007613 PGS000957
(GBE_HC932)
 PSS004715|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE essential (primary hypertension) — AUROC: 0.72352 [0.71925, 0.72779] R²: 0.16706
Incremental AUROC (full-covars): 0.02959
PGS R2 (no covariates): 0.04055
PGS AUROC (no covariates): 0.60837 [0.60349, 0.61326]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007614 PGS000958
(GBE_HC273)
 PSS004403|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Essential hypertension — AUROC: 0.72155 [0.708, 0.7351] R²: 0.17503
Incremental AUROC (full-covars): -0.00192
PGS R2 (no covariates): 0.00286
PGS AUROC (no covariates): 0.52821 [0.51311, 0.54331]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007615 PGS000958
(GBE_HC273)
 PSS004404|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Essential hypertension — AUROC: 0.74478 [0.71204, 0.77751] R²: 0.16987
Incremental AUROC (full-covars): 0.01358
PGS R2 (no covariates): 0.01557
PGS AUROC (no covariates): 0.56972 [0.5318, 0.60763]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007616 PGS000958
(GBE_HC273)
 PSS004405|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Essential hypertension — AUROC: 0.74583 [0.73846, 0.75319] R²: 0.1847
Incremental AUROC (full-covars): 0.01683
PGS R2 (no covariates): 0.02709
PGS AUROC (no covariates): 0.59474 [0.58596, 0.60351]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007617 PGS000958
(GBE_HC273)
 PSS004406|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Essential hypertension — AUROC: 0.73161 [0.71966, 0.74357] R²: 0.19538
Incremental AUROC (full-covars): 0.00693
PGS R2 (no covariates): 0.01804
PGS AUROC (no covariates): 0.56789 [0.55414, 0.58165]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007618 PGS000958
(GBE_HC273)
 PSS004407|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Essential hypertension — AUROC: 0.72364 [0.71923, 0.72805] R²: 0.16114
Incremental AUROC (full-covars): 0.02564
PGS R2 (no covariates): 0.03436
PGS AUROC (no covariates): 0.60148 [0.5964, 0.60656]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009092 PGS001320
(GBE_HC215)
 PSS004349|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hypertension — AUROC: 0.7113 [0.69875, 0.72385] R²: 0.17724
Incremental AUROC (full-covars): 0.00194
PGS R2 (no covariates): 0.01116
PGS AUROC (no covariates): 0.55174 [0.53775, 0.56573]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009093 PGS001320
(GBE_HC215)
 PSS004350|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hypertension — AUROC: 0.75955 [0.7336, 0.78551] R²: 0.22552
Incremental AUROC (full-covars): 0.03121
PGS R2 (no covariates): 0.05514
PGS AUROC (no covariates): 0.62221 [0.59228, 0.65214]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009094 PGS001320
(GBE_HC215)
 PSS004351|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hypertension — AUROC: 0.731 [0.72434, 0.73765] R²: 0.19145
Incremental AUROC (full-covars): 0.03394
PGS R2 (no covariates): 0.05533
PGS AUROC (no covariates): 0.62108 [0.61358, 0.62857]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009095 PGS001320
(GBE_HC215)
 PSS004352|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hypertension — AUROC: 0.73444 [0.72324, 0.74564] R²: 0.21325
Incremental AUROC (full-covars): 0.02055
PGS R2 (no covariates): 0.03841
PGS AUROC (no covariates): 0.59979 [0.58706, 0.61252]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009096 PGS001320
(GBE_HC215)
 PSS004353|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hypertension — AUROC: 0.7189 [0.71489, 0.72291] R²: 0.17852
Incremental AUROC (full-covars): 0.04424
PGS R2 (no covariates): 0.06493
PGS AUROC (no covariates): 0.62908 [0.62467, 0.63349]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009594 PGS001838
(portability-PLR_401)
 PSS009310|
European Ancestry|
20,000 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1882 [0.1748, 0.2016] sex, age, birth date, deprivation index, 16 PCs —
PPM009595 PGS001838
(portability-PLR_401)
 PSS009084|
European Ancestry|
4,136 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1633 [0.1334, 0.1929] sex, age, birth date, deprivation index, 16 PCs —
PPM009596 PGS001838
(portability-PLR_401)
 PSS008638|
European Ancestry|
6,660 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.157 [0.1335, 0.1804] sex, age, birth date, deprivation index, 16 PCs —
PPM009598 PGS001838
(portability-PLR_401)
 PSS008192|
South Asian Ancestry|
6,331 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1567 [0.1326, 0.1807] sex, age, birth date, deprivation index, 16 PCs —
PPM009599 PGS001838
(portability-PLR_401)
 PSS007974|
East Asian Ancestry|
1,810 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1165 [0.0706, 0.162] sex, age, birth date, deprivation index, 16 PCs —
PPM009600 PGS001838
(portability-PLR_401)
 PSS007757|
African Ancestry|
2,484 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1101 [0.071, 0.149] sex, age, birth date, deprivation index, 16 PCs —
PPM009601 PGS001838
(portability-PLR_401)
 PSS008861|
African Ancestry|
3,924 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.0682 [0.0369, 0.0993] sex, age, birth date, deprivation index, 16 PCs —
PPM009597 PGS001838
(portability-PLR_401)
 PSS008412|
Greater Middle Eastern Ancestry|
1,200 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1797 [0.1239, 0.2344] sex, age, birth date, deprivation index, 16 PCs —
PPM011238 PGS002047
(portability-ldpred2_401)
 PSS009310|
European Ancestry|
20,000 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1966 [0.1832, 0.2099] sex, age, birth date, deprivation index, 16 PCs —
PPM011239 PGS002047
(portability-ldpred2_401)
 PSS009084|
European Ancestry|
4,136 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1843 [0.1546, 0.2137] sex, age, birth date, deprivation index, 16 PCs —
PPM011241 PGS002047
(portability-ldpred2_401)
 PSS008412|
Greater Middle Eastern Ancestry|
1,200 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1675 [0.1115, 0.2224] sex, age, birth date, deprivation index, 16 PCs —
PPM011242 PGS002047
(portability-ldpred2_401)
 PSS008192|
South Asian Ancestry|
6,331 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1679 [0.1438, 0.1917] sex, age, birth date, deprivation index, 16 PCs —
PPM011243 PGS002047
(portability-ldpred2_401)
 PSS007974|
East Asian Ancestry|
1,810 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1101 [0.0641, 0.1556] sex, age, birth date, deprivation index, 16 PCs —
PPM011244 PGS002047
(portability-ldpred2_401)
 PSS007757|
African Ancestry|
2,484 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.0996 [0.0603, 0.1385] sex, age, birth date, deprivation index, 16 PCs —
PPM011245 PGS002047
(portability-ldpred2_401)
 PSS008861|
African Ancestry|
3,924 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.0804 [0.0492, 0.1115] sex, age, birth date, deprivation index, 16 PCs —
PPM011240 PGS002047
(portability-ldpred2_401)
 PSS008638|
European Ancestry|
6,660 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension — — Partial Correlation (partial-r): 0.1669 [0.1434, 0.1902] sex, age, birth date, deprivation index, 16 PCs —
PPM013025 PGS002296
(PRS2166_HT)
 PSS009654|
European Ancestry|
2,244 individuals
 PGP000326 |
Maj C et al. Front Cardiovasc Med (2022)
 Reported Trait: Hypertension OR: 3.22 [2.06, 5.1] — — — —
PPM013149 PGS002335
(disease_HYPERTENSION_DIAGNOSED.BOLT-LMM)
 PSS009784|
East Asian Ancestry|
913 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0326 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013100 PGS002335
(disease_HYPERTENSION_DIAGNOSED.BOLT-LMM)
 PSS009783|
African Ancestry|
6,438 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0144 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013198 PGS002335
(disease_HYPERTENSION_DIAGNOSED.BOLT-LMM)
 PSS009785|
European Ancestry|
43,392 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0527 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013247 PGS002335
(disease_HYPERTENSION_DIAGNOSED.BOLT-LMM)
 PSS009786|
South Asian Ancestry|
7,948 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0444 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013388 PGS002407
(disease_HYPERTENSION_DIAGNOSED.P+T.0.0001)
 PSS009783|
African Ancestry|
6,438 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013437 PGS002407
(disease_HYPERTENSION_DIAGNOSED.P+T.0.0001)
 PSS009784|
East Asian Ancestry|
913 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0023 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013486 PGS002407
(disease_HYPERTENSION_DIAGNOSED.P+T.0.0001)
 PSS009785|
European Ancestry|
43,392 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0185 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013535 PGS002407
(disease_HYPERTENSION_DIAGNOSED.P+T.0.0001)
 PSS009786|
South Asian Ancestry|
7,948 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.012 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013584 PGS002456
(disease_HYPERTENSION_DIAGNOSED.P+T.0.001)
 PSS009783|
African Ancestry|
6,438 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013633 PGS002456
(disease_HYPERTENSION_DIAGNOSED.P+T.0.001)
 PSS009784|
East Asian Ancestry|
913 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0028 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013682 PGS002456
(disease_HYPERTENSION_DIAGNOSED.P+T.0.001)
 PSS009785|
European Ancestry|
43,392 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0182 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013731 PGS002456
(disease_HYPERTENSION_DIAGNOSED.P+T.0.001)
 PSS009786|
South Asian Ancestry|
7,948 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0066 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013780 PGS002505
(disease_HYPERTENSION_DIAGNOSED.P+T.0.01)
 PSS009783|
African Ancestry|
6,438 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013829 PGS002505
(disease_HYPERTENSION_DIAGNOSED.P+T.0.01)
 PSS009784|
East Asian Ancestry|
913 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013878 PGS002505
(disease_HYPERTENSION_DIAGNOSED.P+T.0.01)
 PSS009785|
European Ancestry|
43,392 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0115 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013927 PGS002505
(disease_HYPERTENSION_DIAGNOSED.P+T.0.01)
 PSS009786|
South Asian Ancestry|
7,948 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0044 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013976 PGS002554
(disease_HYPERTENSION_DIAGNOSED.P+T.1e-06)
 PSS009783|
African Ancestry|
6,438 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0034 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014025 PGS002554
(disease_HYPERTENSION_DIAGNOSED.P+T.1e-06)
 PSS009784|
East Asian Ancestry|
913 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0057 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014074 PGS002554
(disease_HYPERTENSION_DIAGNOSED.P+T.1e-06)
 PSS009785|
European Ancestry|
43,392 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0128 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014123 PGS002554
(disease_HYPERTENSION_DIAGNOSED.P+T.1e-06)
 PSS009786|
South Asian Ancestry|
7,948 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0086 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014172 PGS002603
(disease_HYPERTENSION_DIAGNOSED.P+T.5e-08)
 PSS009783|
African Ancestry|
6,438 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.004 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014221 PGS002603
(disease_HYPERTENSION_DIAGNOSED.P+T.5e-08)
 PSS009784|
East Asian Ancestry|
913 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.004 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014270 PGS002603
(disease_HYPERTENSION_DIAGNOSED.P+T.5e-08)
 PSS009785|
European Ancestry|
43,392 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.011 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014319 PGS002603
(disease_HYPERTENSION_DIAGNOSED.P+T.5e-08)
 PSS009786|
South Asian Ancestry|
7,948 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.007 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014368 PGS002652
(disease_HYPERTENSION_DIAGNOSED.PolyFun-pred)
 PSS009783|
African Ancestry|
6,438 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0195 age, sex, age*sex, assessment center, genotyping array, 10 PCs See disease_HYPERTENSION_DIAGNOSED.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014417 PGS002652
(disease_HYPERTENSION_DIAGNOSED.PolyFun-pred)
 PSS009784|
East Asian Ancestry|
913 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0417 age, sex, age*sex, assessment center, genotyping array, 10 PCs See disease_HYPERTENSION_DIAGNOSED.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014466 PGS002652
(disease_HYPERTENSION_DIAGNOSED.PolyFun-pred)
 PSS009785|
European Ancestry|
43,392 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0539 age, sex, age*sex, assessment center, genotyping array, 10 PCs See disease_HYPERTENSION_DIAGNOSED.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014515 PGS002652
(disease_HYPERTENSION_DIAGNOSED.PolyFun-pred)
 PSS009786|
South Asian Ancestry|
7,948 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0476 age, sex, age*sex, assessment center, genotyping array, 10 PCs See disease_HYPERTENSION_DIAGNOSED.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014564 PGS002701
(disease_HYPERTENSION_DIAGNOSED.SBayesR)
 PSS009783|
African Ancestry|
6,438 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0146 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014613 PGS002701
(disease_HYPERTENSION_DIAGNOSED.SBayesR)
 PSS009784|
East Asian Ancestry|
913 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0335 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014662 PGS002701
(disease_HYPERTENSION_DIAGNOSED.SBayesR)
 PSS009785|
European Ancestry|
43,392 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0506 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014711 PGS002701
(disease_HYPERTENSION_DIAGNOSED.SBayesR)
 PSS009786|
South Asian Ancestry|
7,948 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Hypertension — — Incremental R2 (full model vs. covariates alone): 0.0453 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014965 PGS002765
(SBP_prscs)
 PSS009939|
European Ancestry|
39,444 individuals
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.57 [1.51, 1.62] — — age, sex, 10 PCs, technical covariates —
PPM014977 PGS002777
(GTG_Hypertension_maxCT)
 PSS009942|
European Ancestry|
21,970 individuals
 PGP000365 |
Wong CK et al. PLoS One (2022)
 Reported Trait: Incident hypertension OR: 1.23 [1.18, 1.27] AUROC: 0.559 [0.55, 0.569] — — —
PPM014978 PGS002778
(GTG_Hypertension_SCT)
 PSS009942|
European Ancestry|
21,970 individuals
 PGP000365 |
Wong CK et al. PLoS One (2022)
 Reported Trait: Incident hypertension OR: 1.26 [1.22, 1.3] AUROC: 0.566 [0.556, 0.576] — — —
PPM015873 PGS002994
(ExPRSweb_Hypertension_20002-1065_LASSOSUM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.638 [1.587, 1.691]
β: 0.494 (0.0162)		 AUROC: 0.628 [0.62, 0.636] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015876 PGS002995
(ExPRSweb_Hypertension_20002-1065_PT_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.556 [1.507, 1.607]
β: 0.442 (0.0164)		 AUROC: 0.612 [0.603, 0.62] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015874 PGS002996
(ExPRSweb_Hypertension_20002-1065_PLINK_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.55 [1.501, 1.6]
β: 0.438 (0.0164)		 AUROC: 0.611 [0.602, 0.619] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015872 PGS002997
(ExPRSweb_Hypertension_20002-1065_DBSLMM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.338 [1.299, 1.379]
β: 0.291 (0.0153)		 AUROC: 0.58 [0.572, 0.59] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015875 PGS002998
(ExPRSweb_Hypertension_20002-1065_PRSCS_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.67 [1.617, 1.725]
β: 0.513 (0.0165)		 AUROC: 0.63 [0.622, 0.639] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015878 PGS002999
(ExPRSweb_Hypertension_20002-1072_LASSOSUM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.036 [1.006, 1.067]
β: 0.0358 (0.015)		 AUROC: 0.508 [0.498, 0.516] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015881 PGS003000
(ExPRSweb_Hypertension_20002-1072_PT_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.034 [1.004, 1.065]
β: 0.0338 (0.015)		 AUROC: 0.507 [0.498, 0.516] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015879 PGS003001
(ExPRSweb_Hypertension_20002-1072_PLINK_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.032 [1.002, 1.063]
β: 0.0318 (0.015)		 AUROC: 0.507 [0.498, 0.516] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015877 PGS003002
(ExPRSweb_Hypertension_20002-1072_DBSLMM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.003 [0.974, 1.033]
β: 0.0026 (0.015)		 AUROC: 0.486 [0.478, 0.495] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015880 PGS003003
(ExPRSweb_Hypertension_20002-1072_PRSCS_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.059 [1.029, 1.09]
β: 0.0573 (0.0149)		 AUROC: 0.516 [0.507, 0.524] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015889 PGS003004
(ExPRSweb_Hypertension_finngen-R4-FG_LASSOSUM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 0.983 [0.955, 1.012]
β: -0.0172 (0.0149)		 AUROC: 0.51 [0.5, 0.519] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015895 PGS003005
(ExPRSweb_Hypertension_finngen-R4-FG_PT_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.016 [0.986, 1.046]
β: 0.0155 (0.015)		 AUROC: 0.506 [0.497, 0.515] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015891 PGS003006
(ExPRSweb_Hypertension_finngen-R4-FG_PLINK_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 0.987 [0.959, 1.017]
β: -0.0127 (0.015)		 AUROC: 0.502 [0.492, 0.511] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015887 PGS003007
(ExPRSweb_Hypertension_finngen-R4-FG_DBSLMM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.015 [0.986, 1.045]
β: 0.0153 (0.0149)		 AUROC: 0.498 [0.489, 0.507] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015893 PGS003008
(ExPRSweb_Hypertension_finngen-R4-FG_PRSCS_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 0.988 [0.959, 1.017]
β: -0.0122 (0.0149)		 AUROC: 0.5 [0.49, 0.508] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015899 PGS003009
(ExPRSweb_Hypertension_finngen-R4-I9_LASSOSUM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 0.99 [0.961, 1.019]
β: -0.0105 (0.015)		 AUROC: 0.512 [0.503, 0.521] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015905 PGS003010
(ExPRSweb_Hypertension_finngen-R4-I9_PT_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.023 [0.993, 1.053]
β: 0.0224 (0.015)		 AUROC: 0.507 [0.498, 0.515] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015901 PGS003011
(ExPRSweb_Hypertension_finngen-R4-I9_PLINK_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.023 [0.993, 1.054]
β: 0.0229 (0.0151)		 AUROC: 0.505 [0.496, 0.514] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015897 PGS003012
(ExPRSweb_Hypertension_finngen-R4-I9_DBSLMM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.019 [0.99, 1.05]
β: 0.0193 (0.0149)		 AUROC: 0.502 [0.493, 0.511] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015903 PGS003013
(ExPRSweb_Hypertension_finngen-R4-I9_PRSCS_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 0.991 [0.962, 1.02]
β: -0.00951 (0.0149)		 AUROC: 0.5 [0.491, 0.509] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015883 PGS003014
(ExPRSweb_Hypertension_I10_LASSOSUM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.065 [1.035, 1.097]
β: 0.0634 (0.015)		 AUROC: 0.517 [0.509, 0.526] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015886 PGS003015
(ExPRSweb_Hypertension_I10_PT_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.07 [1.039, 1.102]
β: 0.0677 (0.015)		 AUROC: 0.522 [0.513, 0.53] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015884 PGS003016
(ExPRSweb_Hypertension_I10_PLINK_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.066 [1.035, 1.098]
β: 0.064 (0.015)		 AUROC: 0.521 [0.512, 0.53] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015882 PGS003017
(ExPRSweb_Hypertension_I10_DBSLMM_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.006 [0.977, 1.036]
β: 0.0057 (0.015)		 AUROC: 0.492 [0.484, 0.502] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015885 PGS003018
(ExPRSweb_Hypertension_I10_PRSCS_MGI_20211120)
 PSS010008|
European Ancestry|
23,316 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.07 [1.038, 1.102]
β: 0.0672 (0.015)		 AUROC: 0.519 [0.51, 0.527] — SEX,AGE,Batch,PC1,PC2,PC3,PC4 —
PPM015890 PGS003019
(ExPRSweb_Hypertension_finngen-R4-FG_LASSOSUM_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.016 [1.004, 1.027]
β: 0.0156 (0.00586)		 AUROC: 0.505 [0.502, 0.509] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015896 PGS003020
(ExPRSweb_Hypertension_finngen-R4-FG_PT_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 0.992 [0.98, 1.003]
β: -0.00832 (0.00587)		 AUROC: 0.506 [0.503, 0.509] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015892 PGS003021
(ExPRSweb_Hypertension_finngen-R4-FG_PLINK_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.01 [0.999, 1.022]
β: 0.0101 (0.00587)		 AUROC: 0.503 [0.5, 0.507] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015888 PGS003022
(ExPRSweb_Hypertension_finngen-R4-FG_DBSLMM_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.002 [0.99, 1.013]
β: 0.0015 (0.00585)		 AUROC: 0.491 [0.488, 0.494] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015894 PGS003023
(ExPRSweb_Hypertension_finngen-R4-FG_PRSCS_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.012 [1.001, 1.024]
β: 0.012 (0.00587)		 AUROC: 0.506 [0.502, 0.509] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015900 PGS003024
(ExPRSweb_Hypertension_finngen-R4-I9_LASSOSUM_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.01 [0.998, 1.022]
β: 0.00982 (0.00587)		 AUROC: 0.503 [0.5, 0.507] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015906 PGS003025
(ExPRSweb_Hypertension_finngen-R4-I9_PT_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 0.991 [0.98, 1.002]
β: -0.00913 (0.00587)		 AUROC: 0.504 [0.501, 0.507] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015902 PGS003026
(ExPRSweb_Hypertension_finngen-R4-I9_PLINK_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.006 [0.994, 1.018]
β: 0.00592 (0.00587)		 AUROC: 0.502 [0.498, 0.505] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015898 PGS003027
(ExPRSweb_Hypertension_finngen-R4-I9_DBSLMM_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.0 [0.989, 1.011]
β: -7e-05 (0.00584)		 AUROC: 0.492 [0.489, 0.494] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM015904 PGS003028
(ExPRSweb_Hypertension_finngen-R4-I9_PRSCS_UKB_20211120)
 PSS010030|
European Ancestry|
203,639 individuals
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Reported Trait: Hypertension OR: 1.009 [0.997, 1.021]
β: 0.00888 (0.00587)		 AUROC: 0.505 [0.502, 0.509] — Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4 —
PPM018280 PGS003586
(PE)
 PSS010956|
European Ancestry|
25,582 individuals
 PGP000462 |
Honigberg MC et al. Nat Med (2023)
 Reported Trait: Pre-eclampsia/eclampsia OR: 1.31 [1.24, 1.38] — — maternal age at delivery, age2, and the first ten principal components of genetic ancestry —
PPM018281 PGS003587
(GH)
 PSS010956|
European Ancestry|
25,582 individuals
 PGP000462 |
Honigberg MC et al. Nat Med (2023)
 Reported Trait: Pre-eclampsia/eclampsia OR: 1.2 [1.14, 1.26] — — maternal age at delivery, age2, and the first ten principal components of genetic ancestry —
PPM020125 PGS004191
(hyper_1)
 PSS011296|
European Ancestry|
45,334 individuals
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Reported Trait: Hypertension — AUROC: 0.70167 — year of birth, sex —
PPM020126 PGS004192
(hyper_2)
 PSS011296|
European Ancestry|
45,334 individuals
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Reported Trait: Hypertension — AUROC: 0.70254 — year of birth, sex —
PPM020127 PGS004193
(hyper_3)
 PSS011296|
European Ancestry|
45,334 individuals
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Reported Trait: Hypertension — AUROC: 0.70358 — year of birth, sex —
PPM020128 PGS004194
(hyper_4)
 PSS011296|
European Ancestry|
45,334 individuals
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Reported Trait: Hypertension — AUROC: 0.69503 — year of birth, sex —
PPM020129 PGS004195
(hyper_5)
 PSS011296|
European Ancestry|
45,334 individuals
 PGP000520 |
Raben TG et al. Sci Rep (2023)
 Reported Trait: Coronary artery disease — AUROC: 0.75746 — year of birth, sex —
PPM020253 PGS004234
(HTN_PAN-UKBB)
 PSS011312|
Multi-ancestry (including European)|
39,035 individuals
 PGP000531 |
Kurniansyah N et al. Nat Commun (2022)
 Reported Trait: Prevelant hypertension — AUROC: 0.763 [0.75, 0.775] — sex, age, age2, study site, race/ethnic background, smoking status, BMI, and 11 ancestral principal components —
PPM020255 PGS004236
(HTN_Unweighted_PRSsum)
 PSS011312|
Multi-ancestry (including European)|
39,035 individuals
 PGP000531 |
Kurniansyah N et al. Nat Commun (2022)
 Reported Trait: Prevelant hypertension OR: 2.1 [1.99, 2.21] AUROC: 0.764 [0.751, 0.777] — sex, age, age2, study site, race/ethnic background, smoking status, BMI, and 11 ancestral principal components PRSsum based on selected CV-PRS (which summed the CV-PRS from the three phenotypes).
PPM020256 PGS004236
(HTN_Unweighted_PRSsum)
 PSS011312|
Multi-ancestry (including European)|
39,035 individuals
 PGP000531 |
Kurniansyah N et al. Nat Commun (2022)
 Reported Trait: New-onset hypertension (normotensive) OR: 1.72 [1.55, 1.91] AUROC: 0.656 — sex, age, age2, study site, race/ethnic background, smoking status, BMI, and 11 ancestral principal components PRSsum based on selected CV-PRS (which summed the CV-PRS from the three phenotypes).
PPM020257 PGS004236
(HTN_Unweighted_PRSsum)
 PSS011312|
Multi-ancestry (including European)|
39,035 individuals
 PGP000531 |
Kurniansyah N et al. Nat Commun (2022)
 Reported Trait: New-onset hypertension (elevated) OR: 1.48 [1.27, 1.71] AUROC: 0.582 — sex, age, age2, study site, race/ethnic background, smoking status, BMI, and 11 ancestral principal components PRSsum based on selected CV-PRS (which summed the CV-PRS from the three phenotypes).
PPM020570 PGS004455
(disease.Hypertension.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Hypertension OR: 1.54004 — — — —
PPM020571 PGS004456
(disease.I10.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: I10 (Essential (primary) hypertension) OR: 1.47509 — — — —
PPM020640 PGS004525
(meta.Hypertension.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Hypertension OR: 1.57854 — — — —
PPM020641 PGS004526
(meta.I10.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: I10 (Essential (primary) hypertension) OR: 1.54547 — — — —
PPM020743 PGS004593
(pe)
 PSS011387|
European Ancestry|
138,317 individuals
 PGP000574 |
Nurkkala J et al. J Hypertens (2022)
 Reported Trait: Gestational hypertension HR: 1.16 [1.14, 1.19] — — Collection year, genotyping batch, and the first 10 genetic principal components —
PPM020744 PGS004593
(pe)
 PSS011388|
European Ancestry|
136,354 individuals
 PGP000574 |
Nurkkala J et al. J Hypertens (2022)
 Reported Trait: Preeclampsia HR: 1.21 [1.18, 1.24] — — Collection year, genotyping batch, and the first 10 genetic principal components —
PPM021010 PGS004785
(HTN_PRSmix_eur)
 PSS011465|
European Ancestry|
9,462 individuals
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Reported Trait: Hypertension — — Incremental R2 (Full model versus model with only covariates): 0.066 [0.056, 0.076] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021011 PGS004786
(HTN_PRSmix_sas)
 PSS011474|
South Asian Ancestry|
8,837 individuals
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Reported Trait: Hypertension — — Incremental R2 (Full model versus model with only covariates): 0.022 [0.016, 0.028] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021012 PGS004787
(HTN_PRSmixPlus_eur)
 PSS011465|
European Ancestry|
9,462 individuals
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Reported Trait: Hypertension — — Incremental R2 (Full model versus model with only covariates): 0.073 [0.063, 0.083] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021013 PGS004788
(HTN_PRSmixPlus_sas)
 PSS011474|
South Asian Ancestry|
8,837 individuals
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Reported Trait: Hypertension — — Incremental R2 (Full model versus model with only covariates): 0.027 [0.02, 0.033] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021722 PGS004934
(hypertension_snpnet_combined)
 PSS011762|
European Ancestry|
8,417 individuals
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Reported Trait: Hypertension OR: 1.42 [1.35, 1.5] AUROC: 0.72 — — —
PPM022364 PGS005144
(Hypertension (PRS-CS; EAS))
 PSS011921|
East Asian Ancestry|
37,185 individuals
 PGP000704 |
Jung HU et al. Commun Biol (2025)
 Reported Trait: Hypertension β: 1.71261 — — age, sex —
PPM022373 PGS005153
(Hypertension (CT-SLEB; EAS+EUR))
 PSS011921|
East Asian Ancestry|
37,185 individuals
 PGP000704 |
Jung HU et al. Commun Biol (2025)
 Reported Trait: Hypertension β: 2.03809 — — age, sex —
PPM037314 PGS019132
(TPMI_401.1_Lassosum2)
 PSS013029|
East Asian Ancestry|
18,140 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Essential hypertension — AUROC: 0.64517 R²: 0.08407 sex, age, array, PCs 1-10 —
PPM037315 PGS019133
(TPMI_401.1_LDpred2)
 PSS013028|
East Asian Ancestry|
18,140 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Essential hypertension — AUROC: 0.6541 R²: 0.09525 sex, age, array, PCs 1-10 —
PPM037316 PGS019134
(TPMI_401.1_MegaPRS)
 PSS013030|
East Asian Ancestry|
18,140 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Essential hypertension — AUROC: 0.64663 R²: 0.08712 sex, age, array, PCs 1-10 —
PPM037317 PGS019135
(TPMI_401.1_PRS-CS)
 PSS013031|
East Asian Ancestry|
18,140 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Essential hypertension — AUROC: 0.65139 R²: 0.09149 sex, age, array, PCs 1-10 —
PPM037318 PGS019136
(TPMI_401.1_PRSmix+)
 PSS013032|
East Asian Ancestry|
18,140 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Essential hypertension — AUROC: 0.67044 R²: 0.11574 sex, age, array, PCs 1-10 —
PPM037319 PGS019137
(TPMI_401.1_SBayesR)
 PSS013033|
East Asian Ancestry|
18,140 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Essential hypertension — AUROC: 0.63722 R²: 0.0764 sex, age, array, PCs 1-10 —
PPM037326 PGS019144
(TPMI_401.3_Lassosum2)
 PSS013047|
East Asian Ancestry|
17,975 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Other hypertensive complications — AUROC: 0.64011 R²: 0.02989 sex, age, array, PCs 1-10 —
PPM037327 PGS019145
(TPMI_401.3_LDpred2)
 PSS013046|
East Asian Ancestry|
17,975 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Other hypertensive complications — AUROC: 0.64963 R²: 0.03411 sex, age, array, PCs 1-10 —
PPM037328 PGS019146
(TPMI_401.3_MegaPRS)
 PSS013048|
East Asian Ancestry|
17,975 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Other hypertensive complications — AUROC: 0.64084 R²: 0.03018 sex, age, array, PCs 1-10 —
PPM037329 PGS019147
(TPMI_401.3_PRS-CS)
 PSS013049|
East Asian Ancestry|
17,975 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Other hypertensive complications — AUROC: 0.64609 R²: 0.03227 sex, age, array, PCs 1-10 —
PPM037330 PGS019148
(TPMI_401.3_SBayesR)
 PSS013050|
East Asian Ancestry|
17,975 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Other hypertensive complications — AUROC: 0.62768 R²: 0.02473 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013046 401.0, 405, 437.2,I15, I16, I67.4, N26.2 —
[
  • 5,246 cases
  • , 12,729 controls
]
,
44.87 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013047 401.0, 405, 437.2,I15, I16, I67.4, N26.2 —
[
  • 5,246 cases
  • , 12,729 controls
]
,
44.87 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS007757 — — 2,484 individuals — African American or Afro-Caribbean Carribean UKB —
PSS004406 — —
[
  • 2,406 cases
  • , 5,425 controls
]
 — South Asian — UKB —
PSS013048 401.0, 405, 437.2,I15, I16, I67.4, N26.2 —
[
  • 5,246 cases
  • , 12,729 controls
]
,
44.87 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS000822 — — 87,413 individuals — European — UKB —
PSS011387 — —
[
  • 8,488 cases
  • , 129,829 controls
]
,
0.0 % Male samples
 — European
(Finnish)		 — FinnGen —
PSS011388 — —
[
  • 6,643 cases
  • , 129,711 controls
]
,
0.0 % Male samples
 — European
(Finnish)		 — FinnGen —
PSS011465 — — 9,462 individuals — European — AllofUs —
PSS008412 — — 1,200 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009310 — — 20,000 individuals — European UK (+ Ireland) UKB —
PSS011474 — — 8,837 individuals — South Asian — G&H —
PSS011296 22,667 sibling pairs — 45,334 individuals — European — UKB —
PSS004711 — —
[
  • 2,034 cases
  • , 4,463 controls
]
 — African unspecified — UKB —
PSS004712 — —
[
  • 298 cases
  • , 1,406 controls
]
 — East Asian — UKB —
PSS004713 — —
[
  • 5,400 cases
  • , 19,505 controls
]
 — European non-white British ancestry UKB —
PSS004714 — —
[
  • 2,513 cases
  • , 5,318 controls
]
 — South Asian — UKB —
PSS004715 — —
[
  • 16,689 cases
  • , 50,736 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS009784 — — 913 individuals — East Asian — UKB —
PSS009783 — — 6,438 individuals — African unspecified — UKB —
PSS009785 — — 43,392 individuals — European Non-British European UKB —
PSS009786 — — 7,948 individuals — South Asian — UKB —
PSS010008 PheCode 401.1 (http://phewascatalog.org/); Binary —
[
  • 11,612 cases
  • , 11,704 controls
]
 — European — MGI —
PSS009084 — — 4,136 individuals — European Poland (NE Europe) UKB —
PSS008192 — — 6,331 individuals — South Asian India (South Asia) UKB —
PSS004349 — —
[
  • 2,919 cases
  • , 3,578 controls
]
 — African unspecified — UKB —
PSS004350 — —
[
  • 446 cases
  • , 1,258 controls
]
 — East Asian — UKB —
PSS004351 — —
[
  • 7,648 cases
  • , 17,257 controls
]
 — European non-white British ancestry UKB —
PSS004352 — —
[
  • 3,161 cases
  • , 4,670 controls
]
 — South Asian — UKB —
PSS004353 — —
[
  • 22,882 cases
  • , 44,543 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS010956 — —
[
  • 1,569 cases
  • , 24,013 controls
]
 — European — HUNT —
PSS010030 PheCode 401.1 (http://phewascatalog.org/); Binary —
[
  • 38,801 cases
  • , 164,838 controls
]
 — European — UKB —
PSS011762 — — 8,417 individuals — European — BBofA —
PSS009654 — —
[
  • 1,284 cases
  • , 960 controls
]
,
61.0 % Male samples
 — European — NR —
PSS008861 — — 3,924 individuals — African unspecified Nigeria (West Africa) UKB —
PSS011364 — — 56,192 individuals — European — UKB —
PSS009939 — — 39,444 individuals — European
(Finnish)		 — FinnGen —
PSS007974 — — 1,810 individuals — East Asian China (East Asia) UKB —
PSS011312 — — 22,701 individuals,
27.8 % Male samples
 — European — ARIC, CHS, FHS, MESA, WHI —
PSS011312 — — 8,822 individuals,
31.9 % Male samples
 — African American or Afro-Caribbean — 6 cohorts
  • ARIC
  • ,CHS
  • ,GENOA
  • ,JHS
  • ,MESA
  • ,WHI
 —
PSS009942 We used the disease definitions described in the supplement of Said et al (2018). PMID: 29955826 —
[
  • 4,394 cases
  • , 17,576 controls
]
,
42.0 % Male samples
 European — UKB —
PSS011312 — — 6,718 individuals,
38.0 % Male samples
 — Hispanic or Latin American — CHS, FHS, HCHS-SOL, MESA, WHI —
PSS011312 — — 794 individuals,
37.9 % Male samples
 — Asian unspecified — MESA, WHI —
PSS013029 401,I10 —
[
  • 5,411 cases
  • , 12,729 controls
]
,
44.97 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013028 401,I10 —
[
  • 5,411 cases
  • , 12,729 controls
]
,
44.97 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013030 401,I10 —
[
  • 5,411 cases
  • , 12,729 controls
]
,
44.97 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013031 401,I10 —
[
  • 5,411 cases
  • , 12,729 controls
]
,
44.97 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013032 401,I10 —
[
  • 5,411 cases
  • , 12,729 controls
]
,
44.97 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013033 401,I10 —
[
  • 5,411 cases
  • , 12,729 controls
]
,
44.97 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS011921 — —
[
  • 17,073 cases
  • , 20,112 controls
]
 — East Asian
(Korean)		 — HEXA —
PSS004403 — —
[
  • 1,956 cases
  • , 4,541 controls
]
 — African unspecified — UKB —
PSS004404 — —
[
  • 259 cases
  • , 1,445 controls
]
 — East Asian — UKB —
PSS004405 — —
[
  • 4,864 cases
  • , 20,041 controls
]
 — European non-white British ancestry UKB —
PSS008638 — — 6,660 individuals — European Italy (South Europe) UKB —
PSS004407 — —
[
  • 15,118 cases
  • , 52,307 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS013049 401.0, 405, 437.2,I15, I16, I67.4, N26.2 —
[
  • 5,246 cases
  • , 12,729 controls
]
,
44.87 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013050 401.0, 405, 437.2,I15, I16, I67.4, N26.2 —
[
  • 5,246 cases
  • , 12,729 controls
]
,
44.87 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —