Trait: abscess

Trait Information
Identifier MONDO_0005227
Description An inflammatory process characterized by the accumulation of pus within a newly formed tissue cavity which is the result of a bacterial, fungal, or parasitic infection or the presence of a foreign body. [NCIT: P378]
Trait category
Other trait
Synonym abscess (disease)

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019572
(TPMI_681.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cellulitis and abscess of fingers toes abscess,
cellulitis		 147,425
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019572/ScoringFiles/PGS019572.txt.gz
PGS019573
(TPMI_681.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cellulitis and abscess of fingers toes abscess,
cellulitis		 309,069
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019573/ScoringFiles/PGS019573.txt.gz
PGS019574
(TPMI_681.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cellulitis and abscess of fingers toes abscess,
cellulitis		 31,805
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019574/ScoringFiles/PGS019574.txt.gz
PGS019575
(TPMI_681.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cellulitis and abscess of fingers toes abscess,
cellulitis		 983,773
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019575/ScoringFiles/PGS019575.txt.gz
PGS019576
(TPMI_681.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cellulitis and abscess of fingers toes abscess,
cellulitis		 996,414
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019576/ScoringFiles/PGS019576.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM037754 PGS019572
(TPMI_681.1_Lassosum2)
 PSS013475|
East Asian Ancestry|
17,970 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cellulitis and abscess of fingers toes — AUROC: 0.57611 R²: 0.00307 sex, age, array, PCs 1-10 —
PPM037755 PGS019573
(TPMI_681.1_LDpred2)
 PSS013474|
East Asian Ancestry|
17,970 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cellulitis and abscess of fingers toes — AUROC: 0.58225 R²: 0.00322 sex, age, array, PCs 1-10 —
PPM037756 PGS019574
(TPMI_681.1_MegaPRS)
 PSS013476|
East Asian Ancestry|
17,970 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cellulitis and abscess of fingers toes — AUROC: 0.57457 R²: 0.00283 sex, age, array, PCs 1-10 —
PPM037757 PGS019575
(TPMI_681.1_PRS-CS)
 PSS013477|
East Asian Ancestry|
17,970 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cellulitis and abscess of fingers toes — AUROC: 0.57797 R²: 0.00306 sex, age, array, PCs 1-10 —
PPM037758 PGS019576
(TPMI_681.1_SBayesR)
 PSS013478|
East Asian Ancestry|
17,970 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cellulitis and abscess of fingers toes — AUROC: 0.57415 R²: 0.00292 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013474 681,L02.51, L02.61, L03.0 —
[
  • 145 cases
  • , 17,825 controls
]
,
45.58 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013475 681,L02.51, L02.61, L03.0 —
[
  • 145 cases
  • , 17,825 controls
]
,
45.58 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013476 681,L02.51, L02.61, L03.0 —
[
  • 145 cases
  • , 17,825 controls
]
,
45.58 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013477 681,L02.51, L02.61, L03.0 —
[
  • 145 cases
  • , 17,825 controls
]
,
45.58 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013478 681,L02.51, L02.61, L03.0 —
[
  • 145 cases
  • , 17,825 controls
]
,
45.58 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —