Trait: contact dermatitis

Trait Information
Identifier MONDO_0005480
Description An inflammatory skin condition caused by direct contact between the skin and either an irritating substance or an allergen. [NCIT: C26743]
Trait category
Other trait
Synonyms 2 synonyms
  • contact dermatitis
  • contact eczema

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019778
(TPMI_939_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 109,945
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019778/ScoringFiles/PGS019778.txt.gz
PGS019779
(TPMI_939_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 939,881
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019779/ScoringFiles/PGS019779.txt.gz
PGS019780
(TPMI_939_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 453,270
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019780/ScoringFiles/PGS019780.txt.gz
PGS019781
(TPMI_939_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 983,816
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019781/ScoringFiles/PGS019781.txt.gz
PGS019782
(TPMI_939_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 928,454
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019782/ScoringFiles/PGS019782.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM037960 PGS019778
(TPMI_939_Lassosum2)
 PSS013681|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.64773 R²: 0.11815 sex, age, array, PCs 1-10 —
PPM037961 PGS019779
(TPMI_939_LDpred2)
 PSS013680|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.6504 R²: 0.1221 sex, age, array, PCs 1-10 —
PPM037962 PGS019780
(TPMI_939_MegaPRS)
 PSS013682|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.64859 R²: 0.11974 sex, age, array, PCs 1-10 —
PPM037963 PGS019781
(TPMI_939_PRS-CS)
 PSS013683|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.64941 R²: 0.1206 sex, age, array, PCs 1-10 —
PPM037964 PGS019782
(TPMI_939_SBayesR)
 PSS013684|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.64793 R²: 0.11859 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013680 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013681 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013682 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013683 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013684 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —