Trait: urinary tract infection

Trait Information
Identifier MONDO_0100338
Trait category
Other trait
Synonym urinary tract infection (disease)

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019458
(TPMI_591_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary tract infection urinary tract infection 206,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019458/ScoringFiles/PGS019458.txt.gz
PGS019459
(TPMI_591_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary tract infection urinary tract infection 939,883
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019459/ScoringFiles/PGS019459.txt.gz
PGS019460
(TPMI_591_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary tract infection urinary tract infection 17,479
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019460/ScoringFiles/PGS019460.txt.gz
PGS019461
(TPMI_591_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary tract infection urinary tract infection 983,825
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019461/ScoringFiles/PGS019461.txt.gz
PGS019462
(TPMI_591_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary tract infection urinary tract infection 936,271
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019462/ScoringFiles/PGS019462.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM037640 PGS019458
(TPMI_591_Lassosum2)
 PSS013361|
East Asian Ancestry|
18,273 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary tract infection — AUROC: 0.66353 R²: 0.09542 sex, age, array, PCs 1-10 —
PPM037641 PGS019459
(TPMI_591_LDpred2)
 PSS013360|
East Asian Ancestry|
18,273 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary tract infection — AUROC: 0.66545 R²: 0.09731 sex, age, array, PCs 1-10 —
PPM037642 PGS019460
(TPMI_591_MegaPRS)
 PSS013362|
East Asian Ancestry|
18,273 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary tract infection — AUROC: 0.66369 R²: 0.09607 sex, age, array, PCs 1-10 —
PPM037643 PGS019461
(TPMI_591_PRS-CS)
 PSS013363|
East Asian Ancestry|
18,273 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary tract infection — AUROC: 0.66504 R²: 0.09682 sex, age, array, PCs 1-10 —
PPM037644 PGS019462
(TPMI_591_SBayesR)
 PSS013364|
East Asian Ancestry|
18,273 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary tract infection — AUROC: 0.66453 R²: 0.09655 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013360 599.0, V13.02,N39.0, Z87.440 —
[
  • 1,581 cases
  • , 16,692 controls
]
,
46.46 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013361 599.0, V13.02,N39.0, Z87.440 —
[
  • 1,581 cases
  • , 16,692 controls
]
,
46.46 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013362 599.0, V13.02,N39.0, Z87.440 —
[
  • 1,581 cases
  • , 16,692 controls
]
,
46.46 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013363 599.0, V13.02,N39.0, Z87.440 —
[
  • 1,581 cases
  • , 16,692 controls
]
,
46.46 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013364 599.0, V13.02,N39.0, Z87.440 —
[
  • 1,581 cases
  • , 16,692 controls
]
,
46.46 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —