Trait: urinary volume

Trait Information
Identifier OBA_0000173
Description The volume of a urine. [AUTO: patterns/patterns/entity_attribute]
Trait category
Other measurement
Synonym volume of urine

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019473
(TPMI_594_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary calculus urinary volume 2,608
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019473/ScoringFiles/PGS019473.txt.gz
PGS019474
(TPMI_594_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary calculus urinary volume 939,830
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019474/ScoringFiles/PGS019474.txt.gz
PGS019475
(TPMI_594_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary calculus urinary volume 81,176
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019475/ScoringFiles/PGS019475.txt.gz
PGS019476
(TPMI_594_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary calculus urinary volume 983,782
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019476/ScoringFiles/PGS019476.txt.gz
PGS019477
(TPMI_594_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary calculus urinary volume 1,071,465
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019477/ScoringFiles/PGS019477.txt.gz
PGS019478
(TPMI_594_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urinary calculus urinary volume 509,717
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019478/ScoringFiles/PGS019478.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM037655 PGS019473
(TPMI_594_Lassosum2)
 PSS013388|
East Asian Ancestry|
19,500 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary calculus — AUROC: 0.67804 R²: 0.13871 sex, age, array, PCs 1-10 —
PPM037656 PGS019474
(TPMI_594_LDpred2)
 PSS013387|
East Asian Ancestry|
19,500 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary calculus — AUROC: 0.68376 R²: 0.14711 sex, age, array, PCs 1-10 —
PPM037657 PGS019475
(TPMI_594_MegaPRS)
 PSS013389|
East Asian Ancestry|
19,500 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary calculus — AUROC: 0.68113 R²: 0.14404 sex, age, array, PCs 1-10 —
PPM037658 PGS019476
(TPMI_594_PRS-CS)
 PSS013390|
East Asian Ancestry|
19,500 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary calculus — AUROC: 0.6836 R²: 0.14614 sex, age, array, PCs 1-10 —
PPM037659 PGS019477
(TPMI_594_PRSmix+)
 PSS013391|
East Asian Ancestry|
19,500 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary calculus — AUROC: 0.68243 R²: 0.14704 sex, age, array, PCs 1-10 —
PPM037660 PGS019478
(TPMI_594_SBayesR)
 PSS013392|
East Asian Ancestry|
19,500 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urinary calculus — AUROC: 0.67771 R²: 0.13894 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013387 592, 594, 788.0, V13.01,N20, N21, N22, N23, Z87.442 —
[
  • 1,423 cases
  • , 18,077 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013388 592, 594, 788.0, V13.01,N20, N21, N22, N23, Z87.442 —
[
  • 1,423 cases
  • , 18,077 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013389 592, 594, 788.0, V13.01,N20, N21, N22, N23, Z87.442 —
[
  • 1,423 cases
  • , 18,077 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013390 592, 594, 788.0, V13.01,N20, N21, N22, N23, Z87.442 —
[
  • 1,423 cases
  • , 18,077 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013391 592, 594, 788.0, V13.01,N20, N21, N22, N23, Z87.442 —
[
  • 1,423 cases
  • , 18,077 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013392 592, 594, 788.0, V13.01,N20, N21, N22, N23, Z87.442 —
[
  • 1,423 cases
  • , 18,077 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —