Trait: kidney volume

Trait Information
Identifier OBA_2050015
Description The volume of a kidney. [AUTO: patterns/patterns/entity_attribute]
Trait category
Other measurement
Synonym volume of kidney

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS019479
(TPMI_594.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Calculus of kidney kidney volume 2,076
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019479/ScoringFiles/PGS019479.txt.gz
PGS019480
(TPMI_594.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Calculus of kidney kidney volume 370,680
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019480/ScoringFiles/PGS019480.txt.gz
PGS019481
(TPMI_594.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Calculus of kidney kidney volume 55,216
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019481/ScoringFiles/PGS019481.txt.gz
PGS019482
(TPMI_594.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Calculus of kidney kidney volume 983,776
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019482/ScoringFiles/PGS019482.txt.gz
PGS019483
(TPMI_594.1_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Calculus of kidney kidney volume 1,041,148
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019483/ScoringFiles/PGS019483.txt.gz
PGS019484
(TPMI_594.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Calculus of kidney kidney volume 993,811
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019484/ScoringFiles/PGS019484.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM037661 PGS019479
(TPMI_594.1_Lassosum2)
 PSS013376|
East Asian Ancestry|
18,882 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Calculus of kidney — AUROC: 0.67037 R²: 0.06471 sex, age, array, PCs 1-10 —
PPM037662 PGS019480
(TPMI_594.1_LDpred2)
 PSS013375|
East Asian Ancestry|
18,882 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Calculus of kidney — AUROC: 0.67594 R²: 0.07087 sex, age, array, PCs 1-10 —
PPM037663 PGS019481
(TPMI_594.1_MegaPRS)
 PSS013377|
East Asian Ancestry|
18,882 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Calculus of kidney — AUROC: 0.67051 R²: 0.06469 sex, age, array, PCs 1-10 —
PPM037664 PGS019482
(TPMI_594.1_PRS-CS)
 PSS013378|
East Asian Ancestry|
18,882 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Calculus of kidney — AUROC: 0.67168 R²: 0.06754 sex, age, array, PCs 1-10 —
PPM037665 PGS019483
(TPMI_594.1_PRSmix+)
 PSS013379|
East Asian Ancestry|
18,882 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Calculus of kidney — AUROC: 0.68199 R²: 0.07495 sex, age, array, PCs 1-10 —
PPM037666 PGS019484
(TPMI_594.1_SBayesR)
 PSS013380|
East Asian Ancestry|
18,882 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Calculus of kidney — AUROC: 0.671 R²: 0.06612 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013375 592.0,N20.0, N20.2 —
[
  • 805 cases
  • , 18,077 controls
]
,
45.34 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013376 592.0,N20.0, N20.2 —
[
  • 805 cases
  • , 18,077 controls
]
,
45.34 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013377 592.0,N20.0, N20.2 —
[
  • 805 cases
  • , 18,077 controls
]
,
45.34 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013378 592.0,N20.0, N20.2 —
[
  • 805 cases
  • , 18,077 controls
]
,
45.34 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013379 592.0,N20.0, N20.2 —
[
  • 805 cases
  • , 18,077 controls
]
,
45.34 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013380 592.0,N20.0, N20.2 —
[
  • 805 cases
  • , 18,077 controls
]
,
45.34 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —