Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003488
(PRS_IL12)
 PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
 General atopic disease (IL-12 related variants) allergic disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003488/ScoringFiles/PGS003488.txt.gz
PGS003757
(wGRS_SLE_HLA)
 PGP000475 |
Kwon YC et al. Arthritis Rheumatol (2023)
 Systemic lupus erythematosus systemic lupus erythematosus 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003757/ScoringFiles/PGS003757.txt.gz
PGS004286
(GenoBoost_alzheimer_s_disease_1)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004286/ScoringFiles/PGS004286.txt.gz
PGS000158
(cGRS_Ovarian)
 PGP000075 |
Shi Z et al. Cancer Med (2019)
 Ovarian cancer ovarian carcinoma 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000158/ScoringFiles/PGS000158.txt.gz
PGS000342
(wGRS_PsA)
 PGP000111 |
Smith MP et al. J Psoriasis Psoriatic Arthritis (2020)
 Psoriatic arthritis psoriatic arthritis 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000342/ScoringFiles/PGS000342.txt.gz
PGS000623
(PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Brain cancer brain cancer 11
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000623/ScoringFiles/PGS000623.txt.gz
PGS000625
(PRSWEB_PHECODE191.11_UKBB-SAIGE-HRC-X191.11_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Brain cancer brain cancer 11
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000625/ScoringFiles/PGS000625.txt.gz
PGS000627
(PRSWEB_PHECODE193_C3-THYROID-GLAND_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Thyroid cancer thyroid carcinoma 11
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000627/ScoringFiles/PGS000627.txt.gz
PGS000656
(NAS-11)
 PGP000119 |
Namjou B et al. BMC Med (2019)
 Non-alcoholic fatty liver disease activity score non-alcoholic fatty liver disease severity measurement 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000656/ScoringFiles/PGS000656.txt.gz
PGS001139
(GBE_BIN_FC10002644)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Light smokers, at least 100 smokes in lifetime smoking behaviour measurement 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001139/ScoringFiles/PGS001139.txt.gz
PGS001254
(GBE_HC177)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Dupuytren's contracture Dupuytren Contracture 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001254/ScoringFiles/PGS001254.txt.gz
PGS001289
(GBE_cancer1065)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Thyroid cancer thyroid carcinoma 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001289/ScoringFiles/PGS001289.txt.gz
PGS003175
(ExPRSweb_VitD_100021-irnt_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Vitamin D vitamin D measurement 11
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003175/ScoringFiles/PGS003175.txt.gz
PGS003396
(PRS-11ASN)
 PGP000415 |
Jee YH et al. Int J Epidemiol (2022)
 Breast cancer breast carcinoma 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003396/ScoringFiles/PGS003396.txt.gz
PGS003440
(GRS11_nonapoeAD)
 PGP000444 |
Petrican R et al. Sci Rep (2023)
 Alzheimer's disease in non APOE APOE carrier status,
Alzheimer disease		 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003440/ScoringFiles/PGS003440.txt.gz
PGS003746
(PRS11_TC)
 PGP000470 |
Xin J et al. EBioMedicine (2023)
 Thyroid cancer thyroid carcinoma 11
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003746/ScoringFiles/PGS003746.txt.gz
PGS004316
(GRS-HLA)
 PGP000547 |
Bui A et al. Front Genet (2023)
 Psoriasis psoriasis 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004316/ScoringFiles/PGS004316.txt.gz
PGS005096
(CAC_GRS)
 PGP000689 |
Mishra PP et al. Am J Prev Cardiol (2024)
 Coronary artery calcification coronary artery calcification 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005096/ScoringFiles/PGS005096.txt.gz
PGS000087
(CC_Thyroid)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Thyroid cancer thyroid carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000087/ScoringFiles/PGS000087.txt.gz
PGS000307
(GRS12_FI)
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 Fasting insulin fasting blood insulin measurement 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000307/ScoringFiles/PGS000307.txt.gz
PGS000308
(GRS12_FIadjBMI)
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 Fasting insulin (body mass index adjusted) BMI-adjusted fasting blood insulin measurement 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000308/ScoringFiles/PGS000308.txt.gz
PGS000326
(GRS-JIA-RFN-20)
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Rheumatoid-factor-negative Polyarthritis (Juvenile Idiophatic Arthritis) polyarticular juvenile idiopathic arthritis, rheumatoid factor negative 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000326/ScoringFiles/PGS000326.txt.gz
PGS000350
(GRS12_POAG)
 PGP000115 |
Fan BJ et al. JAMA Ophthalmol (2019)
 Primary open-angle glaucoma open-angle glaucoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000350/ScoringFiles/PGS000350.txt.gz
PGS000381
(PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colon cancer colon carcinoma 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000381/ScoringFiles/PGS000381.txt.gz
PGS000429
(PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000429/ScoringFiles/PGS000429.txt.gz
PGS000551
(PRSWEB_PHECODE184.11_Phelan-IEOC_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of ovary ovarian neoplasm 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000551/ScoringFiles/PGS000551.txt.gz
PGS000563
(PRSWEB_PHECODE184.11_Phelan-SIOC_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of ovary ovarian neoplasm 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000563/ScoringFiles/PGS000563.txt.gz
PGS000605
(PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of kidney, except pelvis kidney cancer 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000605/ScoringFiles/PGS000605.txt.gz
PGS000606
(PRSWEB_PHECODE189.11_GWAS-Catalog-r2019-05-03-X189.11_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of kidney, except pelvis kidney cancer 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000606/ScoringFiles/PGS000606.txt.gz
PGS000621
(PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Brain cancer brain cancer 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000621/ScoringFiles/PGS000621.txt.gz
PGS000622
(PRSWEB_PHECODE191.11_GWAS-Catalog-r2019-05-03-X191.11_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Brain cancer brain cancer 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000622/ScoringFiles/PGS000622.txt.gz
PGS000641
(PRSWEB_PHECODE202.2_GWAS-Catalog-r2019-05-03-X202.2_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Non-Hodgkin's lymphoma non-Hodgkins lymphoma 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000641/ScoringFiles/PGS000641.txt.gz
PGS000726
(PGS12_CIR)
 PGP000136 |
Emdin CA et al. Gastroenterology (2020)
 Cirrhosis cirrhosis of liver 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000726/ScoringFiles/PGS000726.txt.gz
PGS000797
(CC_Thyroid_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Thyroid cancer thyroid carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000797/ScoringFiles/PGS000797.txt.gz
PGS000922
(GBE_HC170)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Sarcoidosis sarcoidosis 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000922/ScoringFiles/PGS000922.txt.gz
PGS001354
(PRS12_TC)
 PGP000251 |
Song N et al. Cancer Epidemiol Biomarkers Prev (2021)
 Thyroid cancer thyroid carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001354/ScoringFiles/PGS001354.txt.gz
PGS001774
(PRS12_PD)
 PGP000254 |
Chairta PP et al. Genes (Basel) (2021)
 Parkinson's disease Parkinson disease 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001774/ScoringFiles/PGS001774.txt.gz
PGS002273
(GRS12_COVID)
 PGP000302 |
Horowitz JE et al. Nat Genet (2022)
 COVID-19 infection COVID-19 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002273/ScoringFiles/PGS002273.txt.gz
PGS002291
(PRS12_NPC)
 PGP000320 |
He YQ et al. Nat Commun (2022)
 Nasopharyngeal carcinoma nasopharyngeal neoplasm 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002291/ScoringFiles/PGS002291.txt.gz
PGS002585
(repro_ChildLess.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Childless reproductive behaviour measurement 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002585/ScoringFiles/PGS002585.txt.gz
PGS003594
(R_GC-ML-DG_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right granule cell and molecular layer of the dentate gyrus body volume dentate gyrus volume measurement 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003594/ScoringFiles/PGS003594.txt.gz
PGS004241
(PRS12_bladder)
 PGP000542 |
Kim ES et al. NPJ Precis Oncol (2023)
 Bladder cancer urinary bladder carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004241/ScoringFiles/PGS004241.txt.gz
PGS004245
(PRS12_kidney)
 PGP000542 |
Kim ES et al. NPJ Precis Oncol (2023)
 Kidney cancer renal cell carcinoma 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004245/ScoringFiles/PGS004245.txt.gz
PGS004598
(PRS12_HF)
 PGP000576 |
Peng H et al. Nutrients (2023)
 Heart failure heart failure 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004598/ScoringFiles/PGS004598.txt.gz
PGS004700
(HLA-GRS)
 PGP000603 |
Loginovic P et al. Nat Commun (2024)
 Multiple sclerosis multiple sclerosis 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004700/ScoringFiles/PGS004700.txt.gz
PGS004922
(wGRS_AFR)
 PGP000655 |
El-Boraie A et al. Clin Pharmacol Ther (2021)
 Nicotine metabolite ratio nicotine metabolite ratio 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004922/ScoringFiles/PGS004922.txt.gz
PGS000461
(PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000461/ScoringFiles/PGS000461.txt.gz
PGS000462
(PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Squamous cell carcinoma squamous cell carcinoma 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000462/ScoringFiles/PGS000462.txt.gz
PGS000610
(PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Bladder cancer urinary bladder carcinoma 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000610/ScoringFiles/PGS000610.txt.gz
PGS000611
(PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Bladder cancer urinary bladder carcinoma 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000611/ScoringFiles/PGS000611.txt.gz
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