Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004950
(DCM_GWAS_exclAUMC)
 PGP000672 |
Jurgens SJ et al. Nat Genet (2024)
 Dilated cardiomyopathy dilated cardiomyopathy 1,098,677
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004950/ScoringFiles/PGS004950.txt.gz
PGS004951
(DCM_MTAG_exclAUMC)
 PGP000672 |
Jurgens SJ et al. Nat Genet (2024)
 Dilated cardiomyopathy (MTAG) dilated cardiomyopathy 1,075,760
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004951/ScoringFiles/PGS004951.txt.gz
PGS004945
(PRS87_CRC)
 PGP000671 |
Gao P et al. Int J Cancer (2023)
 Colorectal cancer colorectal cancer 87
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004945/ScoringFiles/PGS004945.txt.gz
PGS004944
(lassosum_weights_POAG_CROSS_EUR)
 PGP000670 |
Sekimitsu S et al. JAMA Ophthalmol (2023)
 Primary open-angle glaucoma open-angle glaucoma 144,019
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004944/ScoringFiles/PGS004944.txt.gz
PGS004941
(CAD_MetaPRS)
 PGP000668 |
China Kadoorie Biobank Collaborative Group. et al. Nat Hum Behav (2024)
 Coronary artery disease coronary artery disease 3,711,629
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004941/ScoringFiles/PGS004941.txt.gz
PGS004942
(IS_MetaPRS)
 PGP000668 |
China Kadoorie Biobank Collaborative Group. et al. Nat Hum Behav (2024)
 Ischemic stroke Ischemic stroke 4,765,243
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004942/ScoringFiles/PGS004942.txt.gz
PGS004943
(ICH_MetaPRS)
 PGP000668 |
China Kadoorie Biobank Collaborative Group. et al. Nat Hum Behav (2024)
 Intracerebral hemorrhage intracerebral hemorrhage 2,124,631
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004943/ScoringFiles/PGS004943.txt.gz
PGS004938
(pgs_data_ldpred)
 PGP000666 |
Kovalenko E et al. Front Med (Lausanne) (2024)
 Severe COVID-19 course COVID-19 955,503
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004938/ScoringFiles/PGS004938.txt.gz
PGS004929
(AF_Ldpred2_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Atrial fibrillation atrial fibrillation 178,814
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004929/ScoringFiles/PGS004929.txt.gz
PGS004930
(celiac_disease_snpnet_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Celiac disease celiac disease 463
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004930/ScoringFiles/PGS004930.txt.gz
PGS004931
(gout_snpnet_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Gout gout 1,138
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004931/ScoringFiles/PGS004931.txt.gz
PGS004932
(high_density_lipoprotein_cholesterol_measurement_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 HDL cholesterol high density lipoprotein cholesterol measurement 17,151
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004932/ScoringFiles/PGS004932.txt.gz
PGS004933
(hemorrhoid_LDpred2_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Hemorrhoid hemorrhoid 184,519
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004933/ScoringFiles/PGS004933.txt.gz
PGS004934
(hypertension_snpnet_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Hypertension hypertension 15,056
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004934/ScoringFiles/PGS004934.txt.gz
PGS004935
(hypothyroidism_snpnet_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Hypothyroidism hypothyroidism 6,127
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004935/ScoringFiles/PGS004935.txt.gz
PGS004936
(low_density_lipoprotein_cholesterol_measurement_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 139,875
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004936/ScoringFiles/PGS004936.txt.gz
PGS004937
(triglyceride_measurement_combined)
 PGP000665 |
Moreno-Grau S et al. Human Genomics (2024)
 Triglycerides triglyceride measurement 8,337
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004937/ScoringFiles/PGS004937.txt.gz
PGS004928
(MetS_gSEM)
 PGP000664 |
Park S et al. Nat Genet (2024)
 Metabolic syndrome metabolic syndrome 916,017
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004928/ScoringFiles/PGS004928.txt.gz
PGS004927
(score_resint_max_aa_shortaxis_cm)
 PGP000663 |
Pirruccello JP et al. Eur Heart J (2024)
 Ascending aortic diameter aortic measurement 1,111,632
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004927/ScoringFiles/PGS004927.txt.gz
PGS004926
(Back_3000)
 PGP000661 |
Tsepilov YA et al. J Pers Med (2023)
 Chronic back pain Back pain 1,090,574
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004926/ScoringFiles/PGS004926.txt.gz
PGS004925
(PRS300_CHD)
 PGP000660 |
Kim Y et al. J Intern Med (2023)
 Coronary heart disease coronary artery disease 300
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004925/ScoringFiles/PGS004925.txt.gz
PGS004924
(PRS90_PD)
 PGP000657 |
Cao Z et al. Parkinsonism Relat Disord (2023)
 Parkinson's disease Parkinson disease 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004924/ScoringFiles/PGS004924.txt.gz
PGS004923
(T2D_metaGRS)
 PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,349,896
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004923/ScoringFiles/PGS004923.txt.gz
PGS004922
(wGRS_AFR)
 PGP000655 |
El-Boraie A et al. Clin Pharmacol Ther (2021)
 Nicotine metabolite ratio nicotine metabolite ratio 12
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004922/ScoringFiles/PGS004922.txt.gz
PGS004921
(CAD-GRS)
 PGP000654 |
Huang Y et al. Circ Genom Precis Med (2020)
 Coronary artery disease coronary artery disease 161
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004921/ScoringFiles/PGS004921.txt.gz
PGS004920
(GRS166_AF)
 PGP000652 |
Wang N et al. Eur Heart J (2021)
 Atrial fibrillation atrial fibrillation 166
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004920/ScoringFiles/PGS004920.txt.gz
PGS004918
(PRS8_Synapse)
 PGP000649 |
Lawingco T et al. Neurobiol Aging (2020)
 Late-onset Alzheimers disease (based on SNPs in genes involved in synaptic function) late-onset Alzheimer's disease 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004918/ScoringFiles/PGS004918.txt.gz
PGS004917
(wGRS)
 PGP000648 |
Cui J et al. Arthritis Rheumatol (2020)
 Systemic lupus erythematosus systemic lupus erythematosus 97
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004917/ScoringFiles/PGS004917.txt.gz
PGS004914
(HDL-C_PGS)
 PGP000647 |
Trinder M et al. Arterioscler Thromb Vasc Biol (2019)
 HDL cholesterol high density lipoprotein cholesterol measurement 223
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004914/ScoringFiles/PGS004914.txt.gz
PGS004915
(LDL-C_PGS)
 PGP000647 |
Trinder M et al. Arterioscler Thromb Vasc Biol (2019)
 LDL cholesterol low density lipoprotein cholesterol measurement 223
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004915/ScoringFiles/PGS004915.txt.gz
PGS004916
(Triglycerides_PGS)
 PGP000647 |
Trinder M et al. Arterioscler Thromb Vasc Biol (2019)
 Triglycerides triglyceride measurement 223
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004916/ScoringFiles/PGS004916.txt.gz
PGS004913
(PRSALC)
 PGP000645 |
Schwantes-An TH et al. Hepatol Commun (2024)
 Alcohol-associated liver cirrhosis alcoholic liver cirrhosis 20
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004913/ScoringFiles/PGS004913.txt.gz
PGS004912
(PRS183)
 PGP000643 |
Tian J et al. Genome Med (2024)
 Colorectal neoplasm colorectal carcinoma 183
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004912/ScoringFiles/PGS004912.txt.gz
PGS004910
(hcm.gwama)
 PGP000642 |
Zheng SL et al. Nat Genet (2025)
 Hypertrophic cardiomyopathy hypertrophic cardiomyopathy 374,190
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004910/ScoringFiles/PGS004910.txt.gz
PGS004911
(hcm.mtag)
 PGP000642 |
Zheng SL et al. Nat Genet (2025)
 Hypertrophic cardiomyopathy (MTAG) hypertrophic cardiomyopathy 374,114
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004911/ScoringFiles/PGS004911.txt.gz
PGS004909
(EUR_wGRS7)
 PGP000641 |
El-Boraie A et al. Addict Biol (2019)
 Nicotine metabolite ratio nicotine metabolite ratio 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004909/ScoringFiles/PGS004909.txt.gz
PGS004908
(PRS107_KC)
 PGP000640 |
Purdue MP et al. Nat Genet (2024)
 Kidney cancer renal carcinoma 107
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004908/ScoringFiles/PGS004908.txt.gz
PGS004906
(PRS60_TSH)
 PGP000639 |
Mulder TA et al. Eur J Endocrinol (2023)
 Thyroid stimulating hormone concentration Thyroid stimulating hormone level 60
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004906/ScoringFiles/PGS004906.txt.gz
PGS004907
(PRS31_FT4)
 PGP000639 |
Mulder TA et al. Eur J Endocrinol (2023)
 Free thyroxine concentration thyroxine level 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004907/ScoringFiles/PGS004907.txt.gz
PGS004905
(PRS155_AF)
 PGP000638 |
Ma Y et al. Proc Natl Acad Sci U S A (2023)
 Atrial fibrillation atrial fibrillation 155
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004905/ScoringFiles/PGS004905.txt.gz
PGS004904
(PRS127_CRC)
 PGP000636 |
Jiang F et al. Int J Cancer (2023)
 Colorectal cancer colorectal carcinoma 127
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004904/ScoringFiles/PGS004904.txt.gz
PGS004903
(PRS_ALL)
 PGP000633 |
Al-Janabi A et al. J Allergy Clin Immunol (2023)
 Atopic dermatitis atopic eczema 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004903/ScoringFiles/PGS004903.txt.gz
PGS004902
(PRSBMI)
 PGP000631 |
Chikowore T et al. Genome Med (2024)
 Body mass index (BMI) body mass index 322,639
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004902/ScoringFiles/PGS004902.txt.gz
PGS004900
(GRS_BMI_males)
 PGP000630 |
Wu Y et al. PLoS Genet (2020)
 Body mass index (BMI) body mass index 94
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004900/ScoringFiles/PGS004900.txt.gz
PGS004901
(GRS_BMI_females)
 PGP000630 |
Wu Y et al. PLoS Genet (2020)
 Body mass index (BMI) body mass index 94
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004901/ScoringFiles/PGS004901.txt.gz
PGS004899
(PRS_SCAD)
 PGP000629 |
Saw J et al. Nat Commun (2020)
 Spontaneous coronary artery dissection spontaneous coronary artery dissection 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004899/ScoringFiles/PGS004899.txt.gz
PGS004898
(PRS_AD)
 PGP000624 |
Vasiljevic E et al. Alzheimers Dement (2023)
 Alzheimer's disease Alzheimer disease 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004898/ScoringFiles/PGS004898.txt.gz
PGS004896
(mAlb)
 PGP000623 |
Cañadas-Garre M et al. Int J Mol Sci (2023)
 Microalbuminuria Moderate albuminuria 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004896/ScoringFiles/PGS004896.txt.gz
PGS004897
(UACR)
 PGP000623 |
Cañadas-Garre M et al. Int J Mol Sci (2023)
 Urinary albumin-to-creatinine ratio urinary albumin to creatinine ratio 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004897/ScoringFiles/PGS004897.txt.gz
PGS004893
(overall.hybrid.prs)
 PGP000621 |
Gao G et al. Hum Mol Genet (2022)
 Breast cancer breast carcinoma 56,943
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004893/ScoringFiles/PGS004893.txt.gz
Showing 351 to 400 of 5221 rows