Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002336
(disease_HYPOTHYROIDISM_SELF_REP.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Hypothyroidism hypothyroidism 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002336/ScoringFiles/PGS002336.txt.gz
PGS002337
(biochemistry_LDLdirect.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002337/ScoringFiles/PGS002337.txt.gz
PGS002338
(blood_LYMPHOCYTE_COUNT.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Lymphocyte count lymphocyte count 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002338/ScoringFiles/PGS002338.txt.gz
PGS002339
(blood_MEAN_CORPUSCULAR_HEMOGLOBIN.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Mean corpuscular hemoglobin mean corpuscular hemoglobin 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002339/ScoringFiles/PGS002339.txt.gz
PGS002340
(blood_MEAN_PLATELET_VOL.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Mean platelet volume mean platelet volume 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002340/ScoringFiles/PGS002340.txt.gz
PGS002341
(blood_MONOCYTE_COUNT.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Monocyte count monocyte count 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002341/ScoringFiles/PGS002341.txt.gz
PGS002342
(mental_NEUROTICISM.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Neuroticism neuroticism measurement 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002342/ScoringFiles/PGS002342.txt.gz
PGS002343
(blood_PLATELET_COUNT.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Platelet count platelet count 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002343/ScoringFiles/PGS002343.txt.gz
PGS002344
(disease_PSORIASIS.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002344/ScoringFiles/PGS002344.txt.gz
PGS002345
(blood_RED_COUNT.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Red blood cell count erythrocyte count 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002345/ScoringFiles/PGS002345.txt.gz
PGS002346
(blood_RBC_DISTRIB_WIDTH.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Red blood cell distribution width Red cell distribution width 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002346/ScoringFiles/PGS002346.txt.gz
PGS002347
(disease_RESPIRATORY_ENT.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Respiratory and ear-nose-throat diseases respiratory system disease 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002347/ScoringFiles/PGS002347.txt.gz
PGS002348
(cov_SMOKING_STATUS.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Smoking status smoking status measurement 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002348/ScoringFiles/PGS002348.txt.gz
PGS002349
(bp_SYSTOLICadjMEDz.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Systolic blood pressure systolic blood pressure 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002349/ScoringFiles/PGS002349.txt.gz
PGS002350
(pigment_TANNING.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Tanning suntan 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002350/ScoringFiles/PGS002350.txt.gz
PGS002351
(disease_THYROID_ANY_SELF_REP.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Thyroid (self-reported conditions) thyroid disease 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002351/ScoringFiles/PGS002351.txt.gz
PGS002352
(biochemistry_Cholesterol.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Total cholesterol total cholesterol measurement 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002352/ScoringFiles/PGS002352.txt.gz
PGS002353
(biochemistry_Triglycerides.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Triglycerides triglyceride measurement 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002353/ScoringFiles/PGS002353.txt.gz
PGS002354
(disease_T2D.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002354/ScoringFiles/PGS002354.txt.gz
PGS002355
(biochemistry_VitaminD.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Vitamin D vitamin D measurement 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002355/ScoringFiles/PGS002355.txt.gz
PGS002356
(body_WHRadjBMIz.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Waist-hip ratio waist-hip ratio 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002356/ScoringFiles/PGS002356.txt.gz
PGS002357
(blood_WHITE_COUNT.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 White blood cell count leukocyte count 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002357/ScoringFiles/PGS002357.txt.gz
PGS004789
(hypothyroid_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Hypothyroidism hypothyroidism 1,109,333
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004789/ScoringFiles/PGS004789.txt.gz
PGS000417
(PRSWEB_PHECODE172.1_C43_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 1,109,519
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000417/ScoringFiles/PGS000417.txt.gz
PGS003374
(GSCAN_DrnkWk_2022_PRS_WEIGHTS_AMR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Drinks per week alcohol consumption measurement 1,109,568
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003374/ScoringFiles/PGS003374.txt.gz
PGS003370
(GSCAN_SmkCes_2022_PRS_WEIGHTS_AMR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Smoking cessation smoking cessation 1,109,663
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003370/ScoringFiles/PGS003370.txt.gz
PGS003063
(ExPRSweb_Smoking_SmokingInitiation_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Smoking status smoking status measurement 1,109,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003063/ScoringFiles/PGS003063.txt.gz
PGS003268
(ExPRSweb_Creatine_CKDGen-1000Genomes-DiscoveryMeta-eGFRcrea_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Creatine) glomerular filtration rate,
creatine measurement		 1,109,812
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003268/ScoringFiles/PGS003268.txt.gz
PGS003358
(GSCAN_SmkInit_2022_PRS_WEIGHTS_AMR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Smoking initiation smoking initiation 1,109,850
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003358/ScoringFiles/PGS003358.txt.gz
PGS004888
(CAD_gePGS)
 PGP000619 |
Mandla R et al. Genome Med (2024)
 Coronary artery diseae coronary artery disease 1,110,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004888/ScoringFiles/PGS004888.txt.gz
PGS003963
(DBP_EUR)
 PGP000510 |
Kurniansyah N et al. Nat Commun (2023)
 Diastolic blood pressure diastolic blood pressure 1,110,130
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003963/ScoringFiles/PGS003963.txt.gz
PGS000393
(PRSWEB_PHECODE165.1_LUNG-CANCER_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Lung and bronchus cancer tracheal cancer,
bronchus cancer,
lung cancer		 1,110,438
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000393/ScoringFiles/PGS000393.txt.gz
PGS000394
(PRSWEB_PHECODE165.1_LUNG-CANCER-MESOT_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Lung and bronchus cancer tracheal cancer,
bronchus cancer,
lung cancer		 1,110,438
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000394/ScoringFiles/PGS000394.txt.gz
PGS002276
(QTc_PRS-CS)
 PGP000304 |
Nauffal V et al. Circulation (2022)
 QTc duration QT interval 1,110,494
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002276/ScoringFiles/PGS002276.txt.gz
PGS003068
(ExPRSweb_Smoking_SmokingInitiation_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Smoking status smoking status measurement 1,110,662
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003068/ScoringFiles/PGS003068.txt.gz
PGS000205
(RISK_PC_COGA)
 PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
 Risk-taking tendency (4-domain principal component model) risk-taking behaviour 1,110,737
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000205/ScoringFiles/PGS000205.txt.gz
PGS000203
(GSCAN_DPW_COGA)
 PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
 Alcohol consumption (drinks per week) alcohol consumption measurement 1,110,910
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000203/ScoringFiles/PGS000203.txt.gz
PGS003213
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Sleep apnea sleep apnea 1,111,194
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003213/ScoringFiles/PGS003213.txt.gz
PGS000378
(PRSWEB_PHECODE153.2_C3-COLON_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colon cancer colon carcinoma 1,111,399
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000378/ScoringFiles/PGS000378.txt.gz
PGS000376
(PRSWEB_PHECODE153.2_C18_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colon cancer colon carcinoma 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000376/ScoringFiles/PGS000376.txt.gz
PGS000401
(PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Skin cancer skin carcinoma 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000401/ScoringFiles/PGS000401.txt.gz
PGS000409
(PRSWEB_PHECODE172.1_20001-1059_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000409/ScoringFiles/PGS000409.txt.gz
PGS000413
(PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000413/ScoringFiles/PGS000413.txt.gz
PGS000434
(PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Other non-epithelial skin cancer skin cancer 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000434/ScoringFiles/PGS000434.txt.gz
PGS000438
(PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Other non-epithelial skin cancer skin cancer 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000438/ScoringFiles/PGS000438.txt.gz
PGS000446
(PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000446/ScoringFiles/PGS000446.txt.gz
PGS000570
(PRSWEB_PHECODE185_C3-PROSTATE_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Prostate cancer prostate carcinoma 1,111,493
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000570/ScoringFiles/PGS000570.txt.gz
PGS000574
(PRSWEB_PHECODE185_C61_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Prostate cancer prostate carcinoma 1,111,493
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000574/ScoringFiles/PGS000574.txt.gz
PGS000566
(PRSWEB_PHECODE185_20001-1044_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Prostate cancer prostate carcinoma 1,111,494
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000566/ScoringFiles/PGS000566.txt.gz
PGS000473
(PRSWEB_PHECODE174.1_20001-1002_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 1,111,495
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000473/ScoringFiles/PGS000473.txt.gz
Showing 4351 to 4400 of 5022 rows