Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003426
(prscs_ferritin)
 PGP000432 |
Toivonen J et al. Vox Sanguinis (2023)
 Ferritin ferritin measurement 1,082,414
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003426/ScoringFiles/PGS003426.txt.gz
PGS002761
(Glaucoma_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Glaucoma glaucoma 1,082,518
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002761/ScoringFiles/PGS002761.txt.gz
PGS004825
(RDW_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Red cell distribution width Red cell distribution width 1,082,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004825/ScoringFiles/PGS004825.txt.gz
PGS000202
(PROB_ALC_FT12)
 PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
 Problematic alcohol use alcohol dependence measurement 1,083,002
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000202/ScoringFiles/PGS000202.txt.gz
PGS002769
(Rheumatoid_arthritis_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Seropositive rheumatoid arthritis rheumatoid arthritis 1,083,565
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002769/ScoringFiles/PGS002769.txt.gz
PGS002807
(PRSCS_SBP)
 PGP000384 |
Parcha V et al. Circ Genom Precis Med (2022)
 Systolic blood pressure systolic blood pressure 1,084,157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002807/ScoringFiles/PGS002807.txt.gz
PGS004761
(Eosinophils_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Eosinophil count eosinophil count 1,086,541
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004761/ScoringFiles/PGS004761.txt.gz
PGS003586
(PE)
 PGP000462 |
Honigberg MC et al. Nat Med (2023)
 Pre-eclampsia preeclampsia 1,087,033
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003586/ScoringFiles/PGS003586.txt.gz
PGS002758
(Colorectal_cancer_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Colorectal cancer colorectal cancer 1,087,843
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002758/ScoringFiles/PGS002758.txt.gz
PGS003587
(GH)
 PGP000462 |
Honigberg MC et al. Nat Med (2023)
 Gestational hypertension preeclampsia 1,087,916
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003587/ScoringFiles/PGS003587.txt.gz
PGS004095
(prscs.auto.GCST90018959.Height)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Height body height 1,088,125
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004095/ScoringFiles/PGS004095.txt.gz
PGS003979
(CRC_PRSCS)
 PGP000515 |
Tamlander M et al. Br J Cancer (2023)
 Colorectal cancer colorectal carcinoma 1,088,133
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003979/ScoringFiles/PGS003979.txt.gz
PGS004579
(BRCA_PRSCS)
 PGP000562 |
Youssef O et al. Lab Invest (2024)
 Breast cancer breast carcinoma 1,088,163
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004579/ScoringFiles/PGS004579.txt.gz
PGS003333
(MDD-PRS)
 PGP000399 |
Fang Y et al. Biol Psychiatry (2022)
 Major Depressive Disorder major depressive disorder 1,088,415
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003333/ScoringFiles/PGS003333.txt.gz
PGS002770
(Stroke_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Stroke stroke 1,088,719
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002770/ScoringFiles/PGS002770.txt.gz
PGS002752
(Drinks_per_week_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Alcohol consumption (drinks per week) alcohol consumption quality 1,089,551
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002752/ScoringFiles/PGS002752.txt.gz
PGS004621
(cirrhosis_pgs_eur)
 PGP000594 |
Ghouse J et al. Nat Genet (2024)
 Cirrhosis cirrhosis of liver 1,089,806
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004621/ScoringFiles/PGS004621.txt.gz
PGS001780
(CHD_PRSCS)
 PGP000261 |
Tamlander M et al. Commun Biol (2022)
 Coronary heart disease coronary artery disease 1,090,048
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001780/ScoringFiles/PGS001780.txt.gz
PGS004926
(Back_3000)
 PGP000661 |
Tsepilov YA et al. J Pers Med (2023)
 Chronic back pain Back pain 1,090,574
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004926/ScoringFiles/PGS004926.txt.gz
PGS002755
(Atopic_dermatitis_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Atopic dermatitis atopic eczema 1,090,702
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002755/ScoringFiles/PGS002755.txt.gz
PGS002757
(eGFR_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Chronic kidney disease chronic kidney disease 1,090,783
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002757/ScoringFiles/PGS002757.txt.gz
PGS002764
(LDL_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Hypercholesterolemia Hypercholesterolemia 1,091,280
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002764/ScoringFiles/PGS002764.txt.gz
PGS005203
(G23_BMI_2025_PRSCSx_LC_EUR)
 PGP000724 |
Smit RAJ et al. Nat Med (2025)
 Body mass index (BMI) body mass index 1,091,375
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005203/ScoringFiles/PGS005203.txt.gz - Check Terms/Licenses
PGS002756
(Atrial_fibrillation_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Atrial fibrillation atrial fibrillation 1,091,491
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002756/ScoringFiles/PGS002756.txt.gz
PGS002768
(BMD_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Osteoporosis osteoporosis,
heel bone mineral density		 1,091,549
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002768/ScoringFiles/PGS002768.txt.gz
PGS002771
(Type_2_diabetes_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,091,608
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002771/ScoringFiles/PGS002771.txt.gz
PGS002759
(Depression_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Depression major depressive disorder 1,091,613
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002759/ScoringFiles/PGS002759.txt.gz
PGS001781
(T2D_PRSCS)
 PGP000261 |
Tamlander M et al. Commun Biol (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,091,673
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001781/ScoringFiles/PGS001781.txt.gz
PGS004084
(prscs.auto.GCST005838.Stroke)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Stroke stroke 1,091,747
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004084/ScoringFiles/PGS004084.txt.gz
PGS004098
(prscs.CV.GCST005838.Stroke)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Stroke stroke 1,091,747
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004098/ScoringFiles/PGS004098.txt.gz
PGS002753
(Alzheimer_s_disease_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Alzheimer's disease Alzheimer disease 1,092,011
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002753/ScoringFiles/PGS002753.txt.gz
PGS003332
(PRS_VTE_EUR_GHOUSE)
 PGP000398 |
Ghouse J et al. Nat Genet (2023)
 Venous thromboembolism venous thromboembolism 1,092,045
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003332/ScoringFiles/PGS003332.txt.gz
PGS002240
(prscs_prostatecancer)
 PGP000271 |
Mars N et al. Cell Genom (2022)
 Prostate cancer prostate carcinoma 1,092,093
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002240/ScoringFiles/PGS002240.txt.gz
PGS002766
(Hypothyroidism_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Hypothyroidism hypothyroidism 1,092,122
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002766/ScoringFiles/PGS002766.txt.gz
PGS002762
(Urate_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Gout gout 1,092,214
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002762/ScoringFiles/PGS002762.txt.gz
PGS003443
(PRScsx_T2D_LAT_EURweights)
 PGP000445 |
Huerta-Chagoya A et al. Diabetologia (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,092,496
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003443/ScoringFiles/PGS003443.txt.gz
PGS000882
(25OHD_SBayesR_PGS)
 PGP000228 |
Revez JA et al. Nat Commun (2020)
 25-hydroxyvitamin D vitamin D level 1,094,650
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000882/ScoringFiles/PGS000882.txt.gz
PGS000201
(PROB_ALC_COGA)
 PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
 Problematic alcohol use alcohol dependence measurement 1,094,954
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000201/ScoringFiles/PGS000201.txt.gz
PGS000607
(PRSWEB_PHECODE189.2_20001-1035_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Bladder cancer urinary bladder carcinoma 1,095,241
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000607/ScoringFiles/PGS000607.txt.gz
PGS004845
(tg_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Triglycerides triglyceride measurement 1,095,976
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004845/ScoringFiles/PGS004845.txt.gz
PGS003018
(ExPRSweb_Hypertension_I10_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertension 1,096,197
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003018/ScoringFiles/PGS003018.txt.gz
PGS000608
(PRSWEB_PHECODE189.2_C3-BLADDER_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Bladder cancer urinary bladder carcinoma 1,097,063
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000608/ScoringFiles/PGS000608.txt.gz
PGS004594
(ukb.sbp.female)
 PGP000574 |
Nurkkala J et al. J Hypertens (2022)
 Systolic blood pressure systolic blood pressure 1,097,355
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004594/ScoringFiles/PGS004594.txt.gz
PGS002271
(PRS_MVP)
 PGP000301 |
Roselli C et al. Eur Heart J (2022)
 Mitral valve prolapse Mitral valve prolapse 1,097,364
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002271/ScoringFiles/PGS002271.txt.gz
PGS000900
(PRS_SBP_f)
 PGP000233 |
Kauko A et al. Hypertension (2021)
 Systolic blood pressure (female) systolic blood pressure,
female		 1,098,015
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000900/ScoringFiles/PGS000900.txt.gz
PGS000901
(PRS_SBP_m)
 PGP000233 |
Kauko A et al. Hypertension (2021)
 Systolic blood pressure (male) systolic blood pressure,
male		 1,098,015
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000901/ScoringFiles/PGS000901.txt.gz
PGS000912
(ukb_dbp_prs)
 PGP000240 |
Vaura F et al. Hypertension (2021)
 Diastolic blood pressure diastolic blood pressure 1,098,015
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000912/ScoringFiles/PGS000912.txt.gz
PGS000913
(ukb_sbp_prs)
 PGP000240 |
Vaura F et al. Hypertension (2021)
 Systolic blood pressure systolic blood pressure 1,098,015
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000913/ScoringFiles/PGS000913.txt.gz
PGS000558
(PRSWEB_PHECODE184.11_Phelan-OCCC_LASSOSUM_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of ovary ovarian neoplasm 1,098,236
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000558/ScoringFiles/PGS000558.txt.gz
PGS004946
(DCM_GWAS_exclMGBB)
 PGP000672 |
Jurgens SJ et al. Nat Genet (2024)
 Dilated cardiomyopathy dilated cardiomyopathy 1,098,677
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004946/ScoringFiles/PGS004946.txt.gz
Showing 4351 to 4400 of 5198 rows