Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003732
(PS_T2D_287-HIS-DIAMANTE)
 PGP000469 |
Wedekind LE et al. Diabetologia (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 287
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003732/ScoringFiles/PGS003732.txt.gz
PGS003733
(PS_T2D_287-EUR-DIAMANTE)
 PGP000469 |
Wedekind LE et al. Diabetologia (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 287
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003733/ScoringFiles/PGS003733.txt.gz
PGS003734
(PS_T2D_280-EAS-DIAMANTE)
 PGP000469 |
Wedekind LE et al. Diabetologia (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 280
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003734/ScoringFiles/PGS003734.txt.gz
PGS003735
(PS_T2D_276-AFR-DIAMANTE)
 PGP000469 |
Wedekind LE et al. Diabetologia (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 276
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003735/ScoringFiles/PGS003735.txt.gz
PGS003751
(ModelT2D_over45)
 PGP000472 |
Shoaib M et al. Genet Epidemiol (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 354
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003751/ScoringFiles/PGS003751.txt.gz
PGS003752
(ModelT2D)
 PGP000472 |
Shoaib M et al. Genet Epidemiol (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 333
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003752/ScoringFiles/PGS003752.txt.gz
PGS003867
(T2D_PRScs_ARB)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,068,166
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003867/ScoringFiles/PGS003867.txt.gz
PGS003982
(dbslmm.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,071,764
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003982/ScoringFiles/PGS003982.txt.gz
PGS003998
(lassosum.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 5,548
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003998/ScoringFiles/PGS003998.txt.gz
PGS004014
(lassosum.CV.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 95,649
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004014/ScoringFiles/PGS004014.txt.gz
PGS004024
(ldpred2.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 958,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004024/ScoringFiles/PGS004024.txt.gz
PGS004039
(ldpred2.CV.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 958,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004039/ScoringFiles/PGS004039.txt.gz
PGS004052
(megaprs.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 800,598
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004052/ScoringFiles/PGS004052.txt.gz
PGS004068
(megaprs.CV.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 800,598
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004068/ScoringFiles/PGS004068.txt.gz
PGS004082
(prscs.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,043,329
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004082/ScoringFiles/PGS004082.txt.gz
PGS004106
(pt_clump.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 35
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004106/ScoringFiles/PGS004106.txt.gz
PGS004122
(pt_clump_nested.CV.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 297
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004122/ScoringFiles/PGS004122.txt.gz
PGS004136
(sbayesr.auto.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 930,497
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004136/ScoringFiles/PGS004136.txt.gz
PGS004152
(UKBB_EnsPGS.GCST004773.T2D)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,071,786
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004152/ScoringFiles/PGS004152.txt.gz
PGS004310
(GenoBoost_type_2_diabetes_0)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 7,000
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004310/ScoringFiles/PGS004310.txt.gz
PGS004311
(GenoBoost_type_2_diabetes_1)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 4,000
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004311/ScoringFiles/PGS004311.txt.gz
PGS004312
(GenoBoost_type_2_diabetes_2)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 7,000
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004312/ScoringFiles/PGS004312.txt.gz
PGS004313
(GenoBoost_type_2_diabetes_3)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 8,000
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004313/ScoringFiles/PGS004313.txt.gz
PGS004314
(GenoBoost_type_2_diabetes_4)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,000
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004314/ScoringFiles/PGS004314.txt.gz
PGS004499
(disease.T2D.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004499/ScoringFiles/PGS004499.txt.gz
PGS004569
(meta.T2D.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004569/ScoringFiles/PGS004569.txt.gz
PGS004602
(PRS424_T2D)
 PGP000580 |
Zhuang P et al. Diabetes Care (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 424
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004602/ScoringFiles/PGS004602.txt.gz
PGS004615
(PGS_weights_TMM_All_of_1group)
 PGP000593 |
Ojima T et al. Nat Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 855,161
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004615/ScoringFiles/PGS004615.txt.gz
PGS004616
(PGS_weights_TMM_HighBMI_of_2groups)
 PGP000593 |
Ojima T et al. Nat Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 855,161
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004616/ScoringFiles/PGS004616.txt.gz
PGS004617
(PGS_weights_TMM_LowBMI_of_2groups)
 PGP000593 |
Ojima T et al. Nat Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 855,161
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004617/ScoringFiles/PGS004617.txt.gz
PGS004618
(PGS_weights_BBJ2nd_All_of_1group)
 PGP000593 |
Ojima T et al. Nat Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 728,824
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004618/ScoringFiles/PGS004618.txt.gz
PGS004619
(PGS_weights_BBJ2nd_HighBMI_of_2groups)
 PGP000593 |
Ojima T et al. Nat Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 728,824
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004619/ScoringFiles/PGS004619.txt.gz
PGS004620
(PGS_weights_BBJ2nd_LowBMI_of_2groups)
 PGP000593 |
Ojima T et al. Nat Genet (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 728,824
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004620/ScoringFiles/PGS004620.txt.gz
PGS004837
(t2d_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 3,306,136
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004837/ScoringFiles/PGS004837.txt.gz
PGS004838
(t2d_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004838/ScoringFiles/PGS004838.txt.gz
PGS004839
(t2d_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 4,594,694
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004839/ScoringFiles/PGS004839.txt.gz
PGS004840
(t2d_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004840/ScoringFiles/PGS004840.txt.gz
PGS004859
(T2D_PRS_CS)
 PGP000605 |
Deutsch AJ et al. Diabetes Care (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,108,235
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004859/ScoringFiles/PGS004859.txt.gz
PGS004868
(T2DPGS)
 PGP000617 |
Yun JS et al. Cardiovasc Diabetol (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,580,804
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004868/ScoringFiles/PGS004868.txt.gz
PGS004870
(INTERVENE_MegaPRS_T2D)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 930,506
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004870/ScoringFiles/PGS004870.txt.gz
PGS004887
(T2D_gePGS)
 PGP000619 |
Mandla R et al. Genome Med (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,117,628
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004887/ScoringFiles/PGS004887.txt.gz
PGS004923
(T2D_metaGRS)
 PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,349,896
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004923/ScoringFiles/PGS004923.txt.gz
PGS005108
(PRSdiabetes)
 PGP000697 |
Takase M et al. J Atheroscler Thromb (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 42,845
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005108/ScoringFiles/PGS005108.txt.gz
PGS005110
(PGS_T2D_gw)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,114,950
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005110/ScoringFiles/PGS005110.txt.gz
PGS005111
(PGS_T2D_gwas)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 150
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005111/ScoringFiles/PGS005111.txt.gz
PGS005115
(PGS_T2D_beta_cell)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 30
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005115/ScoringFiles/PGS005115.txt.gz
PGS005116
(PGS_T2D_lipodystrophy)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 20
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005116/ScoringFiles/PGS005116.txt.gz
PGS005117
(PGS_T2D_liver_lipid)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 5
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005117/ScoringFiles/PGS005117.txt.gz
PGS005118
(PGS_T2D_obesity)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 5
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005118/ScoringFiles/PGS005118.txt.gz
PGS005119
(PGS_T2D_proinsulin)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 7
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005119/ScoringFiles/PGS005119.txt.gz
Showing 4551 to 4600 of 5091 rows