Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002097
(portability-ldpred2_960.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Allergy/adverse effect of penicillin drug allergy 742,904
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002097/ScoringFiles/PGS002097.txt.gz
PGS000025
(GRS)
 PGP000015 |
Chouraki V et al. J Alzheimers Dis (2016)
 Alzheimer's disease Alzheimer disease 19
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000025/ScoringFiles/PGS000025.txt.gz
PGS000026
(PHS)
 PGP000016 |
Desikan RS et al. PLoS Med (2017)
 Alzheimer's disease Alzheimer disease 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000026/ScoringFiles/PGS000026.txt.gz
PGS000779
(PGS7_AD)
 PGP000183 |
Zhou X et al. Alzheimers Dement (Amst) (2020)
 Alzheimer's disease Alzheimer disease 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000779/ScoringFiles/PGS000779.txt.gz
PGS000811
(AD-PRS_39)
 PGP000196 |
Najar J et al. Alzheimers Dement (Amst) (2021)
 Alzheimer's disease Alzheimer disease 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000811/ScoringFiles/PGS000811.txt.gz
PGS000812
(AD-PRS_57)
 PGP000196 |
Najar J et al. Alzheimers Dement (Amst) (2021)
 Alzheimer's disease Alzheimer disease 57
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000812/ScoringFiles/PGS000812.txt.gz
PGS000823
(GRS23_AD)
 PGP000207 |
van der Lee SJ et al. Lancet Neurol (2018)
 Alzheimer's disease Alzheimer disease 23
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000823/ScoringFiles/PGS000823.txt.gz
PGS000876
(PRS31_AD)
 PGP000222 |
Leonenko G et al. Ann Clin Transl Neurol (2019)
 Alzheimer's disease Alzheimer disease 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000876/ScoringFiles/PGS000876.txt.gz
PGS000898
(PRS39_AD)
 PGP000231 |
de Rojas I et al. Nat Commun (2021)
 Alzheimer's disease Alzheimer disease 40
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000898/ScoringFiles/PGS000898.txt.gz
PGS001775
(PRS39_AD)
 PGP000255 |
Ebenau JL et al. Alzheimers Dement (Amst) (2021)
 Alzheimer's disease Alzheimer disease 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001775/ScoringFiles/PGS001775.txt.gz
PGS001828
(portability-PLR_290.11)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Alzheimer's disease Alzheimer disease 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001828/ScoringFiles/PGS001828.txt.gz
PGS002249
(AD_PRS_0.5)
 PGP000276 |
Lourida I et al. JAMA (2019)
 Alzheimer's disease Alzheimer disease 249,273
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002249/ScoringFiles/PGS002249.txt.gz
PGS002280
(GRS83_AD)
 PGP000309 |
Bellenguez C et al. Nat Genet (2022)
 Alzheimer's disease Alzheimer disease 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002280/ScoringFiles/PGS002280.txt.gz
PGS002731
(oA-PRS)
 PGP000339 |
Xicota L et al. Neurology (2022)
 Alzheimer's disease Alzheimer disease 17
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002731/ScoringFiles/PGS002731.txt.gz
PGS002753
(Alzheimer_s_disease_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Alzheimer's disease Alzheimer disease 1,092,011
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002753/ScoringFiles/PGS002753.txt.gz
PGS003441
(GRS28_AD)
 PGP000444 |
Petrican R et al. Sci Rep (2023)
 Alzheimer's disease Alzheimer disease 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003441/ScoringFiles/PGS003441.txt.gz
PGS003953
(AD_Bellenguez)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 1,937
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003953/ScoringFiles/PGS003953.txt.gz
PGS003954
(AD_FINNGEN)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 81
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003954/ScoringFiles/PGS003954.txt.gz
PGS003955
(AD_Jun)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 85
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003955/ScoringFiles/PGS003955.txt.gz
PGS003956
(AD_Kunkle_AFR)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003956/ScoringFiles/PGS003956.txt.gz
PGS003957
(AD_Kunkle)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 12,002
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003957/ScoringFiles/PGS003957.txt.gz
PGS003958
(AD_Unweighted_PRSsum)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 14,109
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003958/ScoringFiles/PGS003958.txt.gz
PGS003992
(dbslmm.auto.GCST90012877.AD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Alzheimer's disease Alzheimer disease 1,136,212
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003992/ScoringFiles/PGS003992.txt.gz
PGS004008
(lassosum.auto.GCST90012877.AD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Alzheimer's disease Alzheimer disease 5,663
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004008/ScoringFiles/PGS004008.txt.gz
PGS004034
(ldpred2.auto.GCST90012877.AD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Alzheimer's disease Alzheimer disease 1,046,908
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004034/ScoringFiles/PGS004034.txt.gz
PGS004062
(megaprs.auto.GCST90012877.AD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Alzheimer's disease Alzheimer disease 691,136
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004062/ScoringFiles/PGS004062.txt.gz
PGS004092
(prscs.auto.GCST90012877.AD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Alzheimer's disease Alzheimer disease 1,109,233
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004092/ScoringFiles/PGS004092.txt.gz
PGS004116
(pt_clump.auto.GCST90012877.AD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Alzheimer's disease Alzheimer disease 58
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004116/ScoringFiles/PGS004116.txt.gz
PGS004146
(sbayesr.auto.GCST90012877.AD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Alzheimer's disease Alzheimer disease 915,771
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004146/ScoringFiles/PGS004146.txt.gz
PGS004227
(ad_apoe_gw_pgs)
 PGP000527 |
Green RE et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004227/ScoringFiles/PGS004227.txt.gz
PGS004228
(ad_apoe_0.1_pgs)
 PGP000527 |
Green RE et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 8,863
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004228/ScoringFiles/PGS004228.txt.gz
PGS004229
(ad_noapoe_0.1_pgs)
 PGP000527 |
Green RE et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 8,858
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004229/ScoringFiles/PGS004229.txt.gz
PGS004285
(GenoBoost_alzheimer_s_disease_0)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004285/ScoringFiles/PGS004285.txt.gz
PGS004286
(GenoBoost_alzheimer_s_disease_1)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004286/ScoringFiles/PGS004286.txt.gz
PGS004287
(GenoBoost_alzheimer_s_disease_2)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004287/ScoringFiles/PGS004287.txt.gz
PGS004288
(GenoBoost_alzheimer_s_disease_3)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 200
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004288/ScoringFiles/PGS004288.txt.gz
PGS004289
(GenoBoost_alzheimer_s_disease_4)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 40
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004289/ScoringFiles/PGS004289.txt.gz
PGS004588
(PRS39_Eur)
 PGP000567 |
Jung SH et al. JAMA Netw Open (2022)
 Alzheimer's disease Alzheimer disease 39
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004588/ScoringFiles/PGS004588.txt.gz
PGS004589
(PRS80_trans)
 PGP000567 |
Jung SH et al. JAMA Netw Open (2022)
 Alzheimer's disease Alzheimer disease 80
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004589/ScoringFiles/PGS004589.txt.gz
PGS004590
(PRS363_rand_eff)
 PGP000569 |
Lake J et al. Mol Psychiatry (2023)
 Alzheimer's disease Alzheimer disease 363
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004590/ScoringFiles/PGS004590.txt.gz
PGS004600
(PRS_AD83)
 PGP000578 |
Tomassen J et al. BMC Neurol (2022)
 Alzheimer's disease Alzheimer disease 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004600/ScoringFiles/PGS004600.txt.gz
PGS004863
(PRS74_AD)
 PGP000609 |
Sleiman PM et al. Alzheimers Dement (2023)
 Alzheimer's disease Alzheimer disease 74
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004863/ScoringFiles/PGS004863.txt.gz
PGS004898
(PRS_AD)
 PGP000624 |
Vasiljevic E et al. Alzheimers Dement (2023)
 Alzheimer's disease Alzheimer disease 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004898/ScoringFiles/PGS004898.txt.gz
PGS001348
(GBE_HC1584)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Alzheimer's disease (algorithmically-defined) Alzheimer disease 15
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001348/ScoringFiles/PGS001348.txt.gz
PGS003440
(GRS11_nonapoeAD)
 PGP000444 |
Petrican R et al. Sci Rep (2023)
 Alzheimer's disease in non APOE APOE carrier status,
Alzheimer disease		 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003440/ScoringFiles/PGS003440.txt.gz
PGS000053
(ALZ21_NIA-LOAD)
 PGP000039 |
Tosto G et al. Neurology (2017)
 Alzheimer's disease (late onset) late-onset Alzheimer's disease 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000053/ScoringFiles/PGS000053.txt.gz
PGS000054
(ALZ21_EFIGA)
 PGP000039 |
Tosto G et al. Neurology (2017)
 Alzheimer's disease (late onset) late-onset Alzheimer's disease 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000054/ScoringFiles/PGS000054.txt.gz
PGS003574
(GRS_Dementia21)
 PGP000459 |
Mukadam N et al. PLoS One (2022)
 Alzheimer's disease (late onset) Alzheimer disease 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003574/ScoringFiles/PGS003574.txt.gz
PGS001349
(GBE_HC807)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Alzheimer's disease (time-to-event) Alzheimer disease 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001349/ScoringFiles/PGS001349.txt.gz
PGS003762
(PRS57_amyloid)
 PGP000485 |
Mourtzi N et al. Alzheimers Dement (2023)
 Amyloid beta 42 beta-amyloid 1-42 measurement 57
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003762/ScoringFiles/PGS003762.txt.gz
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