Publications

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000721 0 6 Sadler MC Leveraging large-scale biobank EHRs to enhance pharmacogenetics of cardiometabolic disease medications. Nat Commun 25/03/2025 10.1038/s41467-025-58152-3 40133288
PGP000186 16 32 Kachuri L Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction. Nat Commun 27/11/2020 10.1038/s41467-020-19600-4 33247094
PGP000149 1 1 Huynh-Le MP Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. Nat Commun 23/02/2021 10.1038/s41467-021-21287-0 33623038
PGP000147 0 11 Thareja G Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Nat Commun 23/02/2021 10.1038/s41467-021-21381-3 33623009
PGP000434 1 1 Khurshid S Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass. Nat Commun 21/03/2023 10.1038/s41467-023-37173-w 36944631
PGP000027 1 2 Abraham G Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke. Nat Commun 20/12/2019 10.1038/s41467-019-13848-1 31862893
PGP000436 1 1 Kelemen M Evaluating the cost-effectiveness of polygenic risk score-stratified screening for abdominal aortic aneurysm. Nat Commun 14/09/2024 10.1038/s41467-024-52452-w 39277617
PGP000314 1 1 Pujol-Gualdo N Advancing our understanding of genetic risk factors and potential personalized strategies for pelvic organ prolapse. Nat Commun 23/06/2022 10.1038/s41467-022-31188-5 35739095
PGP000058 0 1 Huynh-Le MP Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. Nat Commun 23/02/2021 10.1038/s41467-021-21287-0 33623038
PGP000511 1 1 Rasooly D Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure. Nat Commun 10/07/2023 10.1038/s41467-023-39253-3 37429843
PGP000164 3 3 Khan Z Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade. Nat Commun 07/06/2021 10.1038/s41467-021-23661-4 34099659
PGP000138 3 3 Fontanillas P Disease risk scores for skin cancers. Nat Commun 08/01/2021 10.1038/s41467-020-20246-5 33420020
PGP000723 26 26 Xiang R Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology and prediction. Nat Commun 07/05/2025 10.1038/s41467-025-59525-4 40335489
PGP000112 4 4 Ho WK European polygenic risk score for prediction of breast cancer shows similar performance in Asian women. Nat Commun 31/07/2020 10.1038/s41467-020-17680-w 32737321
PGP000492 1 3 Thomas M Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations. Nat Commun 02/10/2023 10.1038/s41467-023-41819-0 37783704
PGP000479 0 1 Blauwendraat C Polygenic Parkinson's Disease Genetic Risk Score as Risk Modifier of Parkinsonism in Gaucher Disease. Mov Disord 03/03/2023 10.1002/mds.29342 36869417
PGP000087 1 1 Pihlstrøm L A cumulative genetic risk score predicts progression in Parkinson's disease. Mov Disord 08/02/2016 10.1002/mds.26505 26853697
PGP000250 1 1 Sia MW Polygenic Risk Scores in a Prospective Parkinson's Disease Cohort. Mov Disord 17/08/2021 10.1002/mds.28761 34402545
PGP000569 1 1 Lake J Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease. Mol Psychiatry 18/05/2023 10.1038/s41380-023-02089-w 37198259
PGP000521 1 1 Merino J Genetic predisposition to macronutrient preference and workplace food choices. Mol Psychiatry 23/05/2023 10.1038/s41380-023-02107-x 37217678
PGP000080 1 1 Coleman JRI Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Mol Psychiatry 23/01/2020 10.1038/s41380-019-0546-6 31969693
PGP000221 1 2 Leal LG A polygenic biomarker to identify patients with severe hypercholesterolemia of polygenic origin. Mol Genet Genomic Med 19/04/2020 10.1002/mgg3.1248 32307928
PGP000437 1 1 Wong CK Melanoma risk prediction based on a polygenic risk score and clinical risk factors. Melanoma Res 24/04/2023 10.1097/cmr.0000000000000896 37096571
PGP000658 0 1 Hu C Genetic Predisposition, Sedentary Behavior, and Incident Coronary Artery Disease: A Prospective Chinese Cohort Study. Med Sci Sports Exerc 30/08/2023 10.1249/mss.0000000000003277 37703277
PGP000280 2 2 Kujala UM Polygenic Risk Scores and Physical Activity. Med Sci Sports Exerc 01/07/2020 10.1249/mss.0000000000002290 32049886
PGP000582 2 2 Gorman BR Distinctive cross-ancestry genetic architecture for age-related macular degeneration medRxivPre 21/08/2022 10.1101/2022.08.16.22278855 —
PGP000606 0 1 Szczerbinski L Algorithms for the identification of prevalent diabetes in the All of Us Research Program validated using polygenic scores - a new resource for diabetes precision medicine medRxivPre 05/09/2023 10.1101/2023.09.05.23295061 —
PGP000680 4 4 Barnes DR Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk medRxivPre 04/03/2024 10.1101/2024.02.29.24303243 —
PGP000656 1 22 Ritchie SC Integrated clinical risk prediction of type 2 diabetes with a multifactorial polygenic risk score medRxivPre 22/08/2024 10.1101/2024.08.22.24312440 —
PGP000608 2 2 Zheng SL Genome-wide association analysis reveals insights into the molecular etiology underlying dilated cardiomyopathy medRxivPre 29/09/2023 10.1101/2023.09.28.23295408 —
PGP000192 1 1 Kawai VK Pleiotropy of systemic lupus erythematosus risk alleles and cardiometabolic disorders: A phenome-wide association study and inverse-variance weighted meta-analysis. Lupus 12/05/2021 10.1177/09612033211014952 33977795
PGP000622 0 1 Åberg F Combined use of the ELF test and CLivD score improves prediction of liver-related outcomes in the general population. Liver Int 23/07/2023 10.1111/liv.15681 37485795
PGP000505 0 1 Liu Z Associations of serum uric acid levels with liver disease-related morbidity and mortality: A prospective cohort study of the UK Biobank. Liver Int 29/03/2023 10.1111/liv.15564 36938749
PGP000234 0 1 Kleinstern G Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans. Leukemia 20/07/2021 10.1038/s41375-021-01344-9 34285341
PGP000448 8 8 Berndt SI Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes. Leukemia 22/10/2022 10.1038/s41375-022-01711-0 36273105
PGP000049 1 1 Dai J Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. Lancet Respir Med 17/07/2019 10.1016/S2213-2600(19)30144-4 31326317
PGP000264 2 2 Moll M Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts. Lancet Respir Med 01/07/2020 10.1016/s2213-2600(20)30101-6 32649918
PGP000025 1 1 Belsky DW Polygenic risk and the development and course of asthma: an analysis of data from a four-decade longitudinal study. Lancet Respir Med 28/06/2013 10.1016/S2213-2600(13)70101-2 24429243
PGP000525 0 18 Yajnik CS Polygenic scores of diabetes-related traits in subgroups of type 2 diabetes in India: a cohort study. Lancet Reg Health Southeast Asia 02/05/2023 10.1016/j.lansea.2023.100182 37492423
PGP000292 0 3 Saad M Genetic predisposition to cancer across people of different ancestries in Qatar: a population-based, cohort study. Lancet Oncol 09/02/2022 10.1016/s1470-2045(21)00752-x 35150601
PGP000387 1 2 Qin N Association of the interaction between mosaic chromosomal alterations and polygenic risk score with the risk of lung cancer: an array-based case-control association and prospective cohort study. Lancet Oncol 17/10/2022 10.1016/s1470-2045(22)00600-3 36265503
PGP000235 2 2 Nalls MA Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet Neurol 01/12/2019 10.1016/s1474-4422(19)30320-5 31701892
PGP000207 1 1 van der Lee SJ The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study. Lancet Neurol 16/03/2018 10.1016/s1474-4422(18)30053-x 29555425
PGP000003 1 1 Mega JL Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials. Lancet 04/03/2015 10.1016/S0140-6736(14)61730-X 25748612
PGP000200 1 1 Talmud PJ Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. Lancet 22/02/2013 10.1016/s0140-6736(12)62127-8 23433573
PGP000562 3 3 Youssef O High-Resolution Genotyping of Formalin-Fixed Tissue Accurately Estimates Polygenic Risk Scores in Human Diseases. Lab Invest 15/01/2024 10.1016/j.labinv.2024.100325 38220043
PGP000411 1 1 Steinbrenner I A Polygenic Score for Reduced Kidney Function and Adverse Outcomes in a Chronic Kidney Disease Cohort. Kidney Int 05/12/2022 10.1016/j.kint.2022.11.013 36481179
PGP000124 1 1 Gorski M Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. Kidney Int 30/10/2020 10.1016/j.kint.2020.09.030 33137338
PGP000495 0 2 Bakshi A Association of polygenic scores with chronic kidney disease phenotypes in a longitudinal study of older adults. Kidney Int 29/03/2023 10.1016/j.kint.2023.03.017 37001602
PGP000406 0 1 Gandhi GD Assessing the genetic burden of familial hypercholesterolemia in a large middle eastern biobank. J Transl Med 03/11/2022 10.1186/s12967-022-03697-w 36329474
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