PGS Publication: PGP000525

Publication Information (EuropePMC)
Title Polygenic scores of diabetes-related traits in subgroups of type 2 diabetes in India: a cohort study.
PubMed ID 37492423(Europe PMC)
doi 10.1016/j.lansea.2023.100182
Publication Date May 2, 2023
Journal Lancet Reg Health Southeast Asia
Author(s) Yajnik CS, Wagh R, Kunte P, Asplund O, Ahlqvist E, Bhat D, Shukla SR, Prasad RB.
Released in PGS Catalog: Dec. 15, 2023

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

External PGS Evaluated By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000832
(T2D-GRS)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 384
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000832/ScoringFiles/PGS000832.txt.gz
PGS000834
(CIR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Corrected insulin response (at 30mins during OGTT) insulin response measurement 220
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000834/ScoringFiles/PGS000834.txt.gz
PGS000835
(ISR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Insulin secretion rate insulin secretion measurement 319
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000835/ScoringFiles/PGS000835.txt.gz
PGS000837
(ISI)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Insulin sensitivity index insulin sensitivity measurement 219
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000837/ScoringFiles/PGS000837.txt.gz
PGS000841
(BMI)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Body mass index (BMI) body mass index 122
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000841/ScoringFiles/PGS000841.txt.gz
PGS000842
(WHR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Waist-hip ratio waist-hip ratio 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000842/ScoringFiles/PGS000842.txt.gz
PGS000844
(VAT_Mass)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Predicted visceral adipose tissue visceral adipose tissue measurement 518
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000844/ScoringFiles/PGS000844.txt.gz
PGS000848
(T2D_Adiposity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with adiposity) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000848/ScoringFiles/PGS000848.txt.gz
PGS000849
(T2D_Impaired_Lipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with impaired lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000849/ScoringFiles/PGS000849.txt.gz
PGS000850
(T2D_Insulin_Action)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action) type 2 diabetes mellitus 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000850/ScoringFiles/PGS000850.txt.gz
PGS000851
(T2D_Insulin_Action_Secretion)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action/secretion) type 2 diabetes mellitus 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000851/ScoringFiles/PGS000851.txt.gz
PGS000852
(T2D_Insulin_Secretion_1)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz
PGS000853
(T2D_Insulin_Secretion_2)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000853/ScoringFiles/PGS000853.txt.gz
PGS000854
(T2D_BetaCell)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with beta cell function) type 2 diabetes mellitus 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000854/ScoringFiles/PGS000854.txt.gz
PGS000855
(T2D_Lipodystrophy)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with lipodystrophy) type 2 diabetes mellitus 18
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000855/ScoringFiles/PGS000855.txt.gz
PGS000856
(T2D_LiverLipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with liver lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000856/ScoringFiles/PGS000856.txt.gz
PGS000857
(T2D_Obesity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with obesity) type 2 diabetes mellitus 4
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000857/ScoringFiles/PGS000857.txt.gz
PGS000858
(T2D_Proinsulin)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with proinsulin levels) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000858/ScoringFiles/PGS000858.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM020163 PGS000832
(T2D-GRS)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.78 [1.49, 2.13] — — age, sex and BMI Evaluated on 381 of 384 SNPs based on the availability of variants in the cohort
PPM020164 PGS000857
(T2D_Obesity)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 0.87 [0.77, 0.99] — — sex —
PPM020165 PGS000841
(BMI)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.26 [1.12, 1.42] — — sex —
PPM020166 PGS000842
(WHR)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.17 [1.04, 1.32] — — sex —
PPM020167 PGS000848
(T2D_Adiposity)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.14 [1.01, 1.28] — — sex —
PPM020168 PGS000854
(T2D_BetaCell)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 0.89 [0.79, 1.0] — — sex —
PPM020169 PGS000834
(CIR)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 0.72 [0.6, 0.85] — — age, sex and BMI —
PPM020170 PGS000852
(T2D_Insulin_Secretion_1)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.33 [1.12, 1.58] — — age, sex and BMI —
PPM020171 PGS000853
(T2D_Insulin_Secretion_2)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.32 [1.11, 1.57] — — age, sex and BMI —
PPM020172 PGS000851
(T2D_Insulin_Action_Secretion)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.07 [0.9, 1.28] — — age, sex and BMI —
PPM020173 PGS000850
(T2D_Insulin_Action)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.16 [1.03, 1.3] — — sex —
PPM020174 PGS000858
(T2D_Proinsulin)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.22 [1.03, 1.44] — — age, sex and BMI —
PPM020175 PGS000855
(T2D_Lipodystrophy)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.17 [1.04, 1.31] — — sex —
PPM020176 PGS000849
(T2D_Impaired_Lipids)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.2 [1.0, 1.44] — — age, sex and BMI —
PPM020177 PGS000856
(T2D_LiverLipids)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 1.29 [1.09, 1.54] — — age, sex and BMI —
PPM020178 PGS000835
(ISR)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Type 2 diabetes OR: 0.72 [0.6, 0.85] — — age, sex and BMI —
PPM020179 PGS000837
(ISI)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: HOMA2IR β: -0.09902 (0.047574) — — — —
PPM020180 PGS000841
(BMI)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: BMI β: 0.15427 (0.027228) — — — —
PPM020181 PGS000842
(WHR)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: BMI β: 0.05687 (0.027539) — — — —
PPM020182 PGS000844
(VAT_Mass)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: BMI β: 0.14774 (0.027271) — — — —
PPM020183 PGS000848
(T2D_Adiposity)
 PSS011301|
South Asian Ancestry|
1,282 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: BMI β: 0.06772 (0.027943) — — — —
PPM020185 PGS000841
(BMI)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 1.27 [1.1, 1.47] — — sex —
PPM020186 PGS000842
(WHR)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 1.22 [1.06, 1.41] — — sex —
PPM020187 PGS000848
(T2D_Adiposity)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 1.23 [1.07, 1.43] — — sex —
PPM020188 PGS000854
(T2D_BetaCell)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 0.87 [0.75, 1.0] — — sex —
PPM020189 PGS000834
(CIR)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 0.86 [0.75, 0.99] — — sex —
PPM020190 PGS000852
(T2D_Insulin_Secretion_1)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 1.38 [1.19, 1.59] — — sex —
PPM020191 PGS000835
(ISR)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 0.86 [0.74, 0.99] — — sex —
PPM020192 PGS000851
(T2D_Insulin_Action_Secretion)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 1.17 [1.01, 1.34] — — sex —
PPM020193 PGS000855
(T2D_Lipodystrophy)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 1.16 [1.0, 1.34] — — sex —
PPM020194 PGS000849
(T2D_Impaired_Lipids)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 1.2 [1.03, 1.4] — — sex —
PPM020195 PGS000856
(T2D_LiverLipids)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 1.24 [1.07, 1.43] — — sex —
PPM020196 PGS000832
(T2D-GRS)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 1.5 [1.27, 1.76] — — sex Evaluated on 381 of 384 SNPs based on the availability of variants in the cohort
PPM020197 PGS000841
(BMI)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 1.31 [1.12, 1.53] — — sex —
PPM020198 PGS000834
(CIR)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 0.85 [0.73, 1.0] — — sex —
PPM020199 PGS000852
(T2D_Insulin_Secretion_1)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 1.25 [1.08, 1.46] — — sex —
PPM020200 PGS000853
(T2D_Insulin_Secretion_2)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 1.24 [1.07, 1.45] — — sex —
PPM020201 PGS000850
(T2D_Insulin_Action)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 1.17 [1.0, 1.36] — — sex —
PPM020202 PGS000858
(T2D_Proinsulin)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 1.2 [1.03, 1.4] — — sex —
PPM020203 PGS000855
(T2D_Lipodystrophy)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 1.18 [1.01, 1.37] — — sex —
PPM020204 PGS000849
(T2D_Impaired_Lipids)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 1.26 [1.07, 1.49] — — sex —
PPM020205 PGS000856
(T2D_LiverLipids)
 PSS011303|
South Asian Ancestry|
729 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild obesity-related diabetes OR: 1.31 [1.12, 1.53] — — sex —
PPM020206 PGS000856
(T2D_LiverLipids)
 PSS011304|
South Asian Ancestry|
482 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin-resistant diabetes OR: 2.04 [1.26, 3.3] — — sex —
PPM020207 PGS000832
(T2D-GRS)
 PSS011305|
South Asian Ancestry|
624 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild age-related diabetes OR: 1.54 [1.27, 1.87] — — sex Evaluated on 381 of 384 SNPs based on the availability of variants in the cohort
PPM020208 PGS000841
(BMI)
 PSS011305|
South Asian Ancestry|
624 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild age-related diabetes OR: 0.79 [0.65, 0.97] — — sex —
PPM020209 PGS000854
(T2D_BetaCell)
 PSS011305|
South Asian Ancestry|
624 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild age-related diabetes OR: 0.81 [0.67, 0.97] — — sex —
PPM020210 PGS000852
(T2D_Insulin_Secretion_1)
 PSS011305|
South Asian Ancestry|
624 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild age-related diabetes OR: 1.33 [1.1, 1.61] — — sex —
PPM020211 PGS000853
(T2D_Insulin_Secretion_2)
 PSS011305|
South Asian Ancestry|
624 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild age-related diabetes OR: 1.32 [1.1, 1.59] — — sex —
PPM020212 PGS000851
(T2D_Insulin_Action_Secretion)
 PSS011305|
South Asian Ancestry|
624 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild age-related diabetes OR: 1.45 [1.19, 1.78] — — sex —
PPM020213 PGS000850
(T2D_Insulin_Action)
 PSS011305|
South Asian Ancestry|
624 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild age-related diabetes OR: 1.26 [1.04, 1.53] — — sex —
PPM020214 PGS000858
(T2D_Proinsulin)
 PSS011305|
South Asian Ancestry|
624 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Mild age-related diabetes OR: 1.23 [1.01, 1.48] — — sex —
PPM020184 PGS000832
(T2D-GRS)
 PSS011302|
South Asian Ancestry|
830 individuals
 PGP000525 |
Yajnik CS et al. Lancet Reg Health Southeast Asia (2023)
|Ext.		 Reported Trait: Severe insulin deficiency diabetes OR: 1.66 [1.42, 1.93] — — sex Evaluated on 381 of 384 SNPs based on the availability of variants in the cohort

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011301 — —
[
  • 821 cases
  • , 461 controls
]
 — South Asian
(Indian)		 — WellGen —
PSS011302 — —
[
  • 369 cases
  • , 461 controls
]
 — South Asian
(Indian)		 — WellGen —
PSS011303 — —
[
  • 268 cases
  • , 461 controls
]
 — South Asian
(Indian)		 — WellGen —
PSS011304 — —
[
  • 21 cases
  • , 461 controls
]
 — South Asian
(Indian)		 — WellGen —
PSS011305 — —
[
  • 163 cases
  • , 461 controls
]
 — South Asian
(Indian)		 — WellGen —