PGS Publication: PGP000282

Publication Information (EuropePMC)
Title An early prediction model for gestational diabetes mellitus based on genetic variants and clinical characteristics in China.
PubMed ID 35073990(Europe PMC)
doi 10.1186/s13098-022-00788-y
Publication Date Jan. 24, 2022
Journal Diabetol Metab Syndr
Author(s) Wu Q, Chen Y, Zhou M, Liu M, Zhang L, Liang Z, Chen D.
Released in PGS Catalog: Feb. 16, 2022

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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South Asian
Additional Asian Ancestries
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Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002256
(GRS4_GDM)
 PGP000282 |
Wu Q et al. Diabetol Metab Syndr (2022)
 Gestational diabetes mellitus in early pregnancy gestational diabetes 4
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002256/ScoringFiles/PGS002256.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM012834 PGS002256
(GRS4_GDM)
 PSS009573|
East Asian Ancestry|
985 individuals
 PGP000282 |
Wu Q et al. Diabetol Metab Syndr (2022)
 Reported Trait: Gestational diabetes mellitus in early pregnancy — AUROC: 0.62 [0.573, 0.667] — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009573 — —
[
  • 191 cases
  • , 794 controls
]
,
0.0 % Male samples
 — East Asian
(Chinese)		 — NR —