PGS Publication: PGP000812

Publication Information (EuropePMC)
Title Childhood maltreatment, genetic risk, and subsequent risk of arrhythmias: a prospective cohort study.
PubMed ID 38912597(Europe PMC)
doi 10.1080/20008066.2024.2366055
Publication Date June 24, 2024
Journal Eur J Psychotraumatol
Author(s) Chen Y, Xue H, Zhou J, Shu X, He Z, Ai S, Feng H, Zhang J, Liang YY, Lv Y, Zhou Y.
Released in PGS Catalog: June 17, 2026

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
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Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS012577
(GRS134_AF)
 PGP000812 |
Chen Y et al. Eur J Psychotraumatol (2024)
 Atrial fibrillation atrial fibrillation 134
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012577/ScoringFiles/PGS012577.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM030728 PGS012577
(GRS134_AF)
 PSS012268|
European Ancestry|
151,741 individuals
 PGP000812 |
Chen Y et al. Eur J Psychotraumatol (2024)
 Reported Trait: Incident atrial fibrillation — — Hazard ratio (HR, high vs low tertile): 3.56 [3.26, 3.88] age, sex, ethnicity, assessment center, employment status, education level,Townsend Deprivation Index, smoking status, alcohol consumption status, physical activity, and healthy diet score —
PPM030727 PGS012577
(GRS134_AF)
 PSS012268|
European Ancestry|
151,741 individuals
 PGP000812 |
Chen Y et al. Eur J Psychotraumatol (2024)
 Reported Trait: Incident atrial fibrillation x childhood maltreatment interaction — — Hazard ratio (HR, 3-5 childhood maltreatment and high PRS vs. no childhood maltreatment and low PRS): 5.31 [4.36, 6.48] age, sex, ethnicity, assessment centre, employment status, education level, Townsend Deprivation Index, smoking status, alcohol consumption status, physical activity, and healthy diet score —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS012268 — — 151,741 individuals,
43.4 % Male samples
 Mean = 55.8 years
Sd = 7.7 years		 European — UKB —