PGS Publication: PGP000861

Publication Information (EuropePMC)
Title Outdoor walking, genetic predisposition, and the risk of incident osteoporosis among older adults: A prospective large population-based cohort study.
PubMed ID 38771526(Europe PMC)
doi 10.1007/s00198-024-07122-4
Publication Date May 21, 2024
Journal Osteoporos Int
Author(s) Yue YS, Liu Y, Lu K, Shi Q, Zhou KX, Li C.
Released in PGS Catalog: Oct. 23, 2026

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
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Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS020003
(GRS14_osteoporosis)
 PGP000861 |
Yue YS et al. Osteoporos Int (2024)
 Osteoporosis osteoporosis 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS020003/ScoringFiles/PGS020003.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM038301 PGS020003
(GRS14_osteoporosis)
 PSS013908|
East Asian Ancestry|
24,700 individuals
 PGP000861 |
Yue YS et al. Osteoporos Int (2024)
 Reported Trait: Incident osteoporosis OR: 1.44 [1.18, 1.77] — — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013908 — — 24,700 individuals,
48.1 % Male samples
 Mean = 68.4 years
Sd = 5.8 years		 East Asian — Kunshan —