Polygenic Score (PGS) ID: PGS019954

Predicted Trait
Reported Trait Gastric Cancer
Mapped Trait(s) gastric cancer (MONDO_0001056)
Released in PGS Catalog: Aug. 26, 2026
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Score Details

Score Construction
PGS Name PRS12_GC
Development Method
Name Genome-wide significant SNPs
Parameters NR
Variants
Original Genome Build NR
Number of Variants 12
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000844
Citation (link to publication) Xu HM et al. JAMA Netw Open (2024)
Ancestry Distribution
Source of Variant
Associations (GWAS)
East Asian: 100%
2,816 individuals (100%)
Score Development/Training
East Asian: 100%
49,912 individuals (100%)
PGS Evaluation
East Asian: 100%
2 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
GWAS Catalog: GCST90551883
Europe PMC: 38809553
 2,816 individuals East Asian NR
Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 49,912 individuals,
42.75 % Male samples
 East Asian CKB — — — — —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM038148 PSS013840|
East Asian Ancestry|
50,316 individuals
 PGP000844 |
Xu HM et al. JAMA Netw Open (2024)
 Reported Trait: Gastric cancer HR: 1.13 [1.03, 1.24] — — age, sex, regions, PC —
PPM038149 PSS013841|
East Asian Ancestry|
1,394 individuals
 PGP000844 |
Xu HM et al. JAMA Netw Open (2024)
 Reported Trait: Gastric cancer HR: 1.14 [1.02, 1.28] — — age, sex, PC —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS013840 — — 50,316 individuals,
42.79 % Male samples
 — East Asian — CKB —
PSS013841 — — 1,394 individuals,
62.2 % Male samples
 — East Asian — NR —