Trait: eye disease

Experimental Factor Ontology (EFO) Information
Identifier EFO_0003966
Description A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIT: C26767]
Trait category
Other disease
Synonyms 9 synonyms
  • disease of eye
  • disease of eyeball of camera-type eye
  • disease or disorder of eyeball of camera-type eye
  • disorder of eye
  • disorder of eyeball of camera-type eye
  • eye disease
  • eye disorder
  • eyeball of camera-type eye disease
  • eyeball of camera-type eye disease or disorder
Mapped terms 16 mapped terms
  • DOID:5614
  • ICD10:H44
  • ICD10:H44.9
  • ICD9:360
  • ICD9:360.89
  • ICD9:360.9
  • ICD9:379.8
  • ICD9:379.90
  • MESH:D005128
  • MONDO:0005328
  • MeSH:D005128
  • NCIT:C26767
  • NCIt:C26767
  • SCTID:371405004
  • UMLS:C0015397
  • Wikipedia:Eye_disease
Child trait(s) 16 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "eye disease" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS000137
(MTAG_glaucoma)
PGP000066 |
Craig JE et al. Nat Genet (2020)
Glaucoma glaucoma 2,673
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000137/ScoringFiles/PGS000137.txt.gz
PGS000341
(GRS33_SSc)
PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
Systemic sclerosis systemic scleroderma 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000341/ScoringFiles/PGS000341.txt.gz
PGS000350
(GRS12_POAG)
PGP000115 |
Fan BJ et al. JAMA Ophthalmol (2019)
Primary open-angle glaucoma open-angle glaucoma 12
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000350/ScoringFiles/PGS000350.txt.gz
PGS000617
(PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Cancer of eye ocular cancer 834,009
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000617/ScoringFiles/PGS000617.txt.gz
PGS000764
(PRS23_POAG)
PGP000169 |
Cole BS et al. Invest Ophthalmol Vis Sci (2021)
Primary-open angle glaucoma open-angle glaucoma 23
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000764/ScoringFiles/PGS000764.txt.gz
PGS000819
(PRS_DR)
PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
Diabetic retinopathy diabetic retinopathy 3,537,914
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000819/ScoringFiles/PGS000819.txt.gz
PGS000862
(DR)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Diabetic Retinopathy diabetic retinopathy 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000862/ScoringFiles/PGS000862.txt.gz
PGS000966
(GBE_HC26)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Iritis iritis 1
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000966/ScoringFiles/PGS000966.txt.gz
PGS000990
(GBE_HC878)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Retinal detachments and breaks (time-to-event) retinal detachment,
retinal break
237
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000990/ScoringFiles/PGS000990.txt.gz
PGS001013
(GBE_BIN_FC5006148)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Macular degeneration macular degeneration 53
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001013/ScoringFiles/PGS001013.txt.gz
PGS001028
(GBE_BIN_FC1006148)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Diabetic eye disease diabetic eye disease 123
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001028/ScoringFiles/PGS001028.txt.gz
PGS001029
(GBE_HC866)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Other disorders of cornea (time-to-event) corneal disease 22
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001029/ScoringFiles/PGS001029.txt.gz
PGS001137
(GBE_HC302)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Retinal detachment retinal detachment 321
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001137/ScoringFiles/PGS001137.txt.gz
PGS001275
(GBE_HC880)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Other retinal disorders (time-to-event) retinopathy 6
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001275/ScoringFiles/PGS001275.txt.gz
PGS001276
(GBE_HC881)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Retinal disorders in diseases classified elsewhere (time-to-event) retinopathy 185
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001276/ScoringFiles/PGS001276.txt.gz
PGS001302
(GBE_HC25)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Cataract cataract 1,214
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001302/ScoringFiles/PGS001302.txt.gz
PGS001303
(GBE_HC872)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Other cataract (time-to-event) cataract 480
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001303/ScoringFiles/PGS001303.txt.gz
PGS001308
(GBE_HC321)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Sjogren's syndrome/sicca syndrome Sjogren syndrome 7
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001308/ScoringFiles/PGS001308.txt.gz
PGS001321
(GBE_BIN_FC2006148)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Eye problems/disorders (Glaucoma) glaucoma 1,103
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001321/ScoringFiles/PGS001321.txt.gz
PGS001322
(GBE_HC276)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Glaucoma glaucoma 655
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001322/ScoringFiles/PGS001322.txt.gz
PGS001323
(GBE_HC882)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Glaucoma (time-to-event) glaucoma 2,066
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001323/ScoringFiles/PGS001323.txt.gz
PGS001819
(portability-PLR_250.7)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Diabetic retinopathy diabetic retinopathy 249
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001819/ScoringFiles/PGS001819.txt.gz
PGS001833
(portability-PLR_361)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Retinal detachments and defects retinal detachment 3,737
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001833/ScoringFiles/PGS001833.txt.gz
PGS001834
(portability-PLR_362.29)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Macular degeneration (senile) of retina NOS age-related macular degeneration 157
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001834/ScoringFiles/PGS001834.txt.gz
PGS001835
(portability-PLR_364.5)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Corneal dystrophy Corneal dystrophy 38
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001835/ScoringFiles/PGS001835.txt.gz
PGS001836
(portability-PLR_365)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Glaucoma glaucoma 7,052
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001836/ScoringFiles/PGS001836.txt.gz
PGS001837
(portability-PLR_366)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Cataract cataract 11,617
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001837/ScoringFiles/PGS001837.txt.gz
PGS002027
(portability-ldpred2_250.7)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Diabetic retinopathy diabetic retinopathy 389,029
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002027/ScoringFiles/PGS002027.txt.gz
PGS002040
(portability-ldpred2_361)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Retinal detachments and defects retinal detachment 706,872
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002040/ScoringFiles/PGS002040.txt.gz
PGS002041
(portability-ldpred2_362.29)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Macular degeneration (senile) of retina NOS age-related macular degeneration 116,538
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002041/ScoringFiles/PGS002041.txt.gz
PGS002042
(portability-ldpred2_364.5)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Corneal dystrophy Corneal dystrophy 59,944
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002042/ScoringFiles/PGS002042.txt.gz
PGS002043
(portability-ldpred2_365)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Glaucoma glaucoma 672,952
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002043/ScoringFiles/PGS002043.txt.gz
PGS002044
(portability-ldpred2_366)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Cataract cataract 711,169
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002044/ScoringFiles/PGS002044.txt.gz
PGS002045
(portability-ldpred2_371)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Inflammation of the eye eye disease,
eye inflammation
527,030
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002045/ScoringFiles/PGS002045.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000422 PGS000137
(MTAG_glaucoma)
PSS000245|
European Ancestry|
1,795 individuals
PGP000066 |
Craig JE et al. Nat Genet (2020)
Reported Trait: Primary open-angle glaucoma (POAG) AUROC: 0.8 age, sex, self-reported family history
PPM000426 PGS000137
(MTAG_glaucoma)
PSS000249|
South Asian Ancestry|
7,033 individuals
PGP000066 |
Craig JE et al. Nat Genet (2020)
Reported Trait: Glaucoma AUROC: 0.76 [0.73, 0.79] age, sex Model 3
PPM000424 PGS000137
(MTAG_glaucoma)
PSS000248|
European Ancestry|
3,112 individuals
PGP000066 |
Craig JE et al. Nat Genet (2020)
Reported Trait: Glaucoma AUROC: 0.75 [0.73, 0.76] age, sex Model 3
PPM000429 PGS000137
(MTAG_glaucoma)
PSS000247|
European Ancestry|
3,112 individuals
PGP000066 |
Craig JE et al. Nat Genet (2020)
Reported Trait: Primary open-angle glaucoma (POAG) AUROC: 0.76 [0.72, 0.81] age, sex Model 3
PPM000425 PGS000137
(MTAG_glaucoma)
PSS000249|
South Asian Ancestry|
7,033 individuals
PGP000066 |
Craig JE et al. Nat Genet (2020)
Reported Trait: Glaucoma AUROC: 0.64 [0.59, 0.68] Model 1
PPM000423 PGS000137
(MTAG_glaucoma)
PSS000248|
European Ancestry|
3,112 individuals
PGP000066 |
Craig JE et al. Nat Genet (2020)
Reported Trait: Glaucoma AUROC: 0.66 [0.64, 0.68] Model 1
PPM000428 PGS000137
(MTAG_glaucoma)
PSS000247|
European Ancestry|
3,112 individuals
PGP000066 |
Craig JE et al. Nat Genet (2020)
Reported Trait: Primary open-angle glaucoma (POAG) AUROC: 0.67 [0.63, 0.72] Model 1
PPM000427 PGS000137
(MTAG_glaucoma)
PSS000246|
European Ancestry|
965 individuals
PGP000066 |
Craig JE et al. Nat Genet (2020)
Reported Trait: Glaucoma in MYOC p.Gln368Ter carriers HR (Hazard Ratio; highest vs. lowest tertile of PRS): 3.4 [1.7, 6.6] sex, PCs 1-6
PPM000421 PGS000137
(MTAG_glaucoma)
PSS000245|
European Ancestry|
1,795 individuals
PGP000066 |
Craig JE et al. Nat Genet (2020)
Reported Trait: Primary open-angle glaucoma (POAG) AUROC: 0.71 [0.66, 0.77]
PPM000970 PGS000341
(GRS33_SSc)
PSS000489|
European Ancestry|
339 individuals
PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
Reported Trait: Systemic sclerosis AUROC: 0.787 [0.73, 0.84] Systemic sclerosis status, age and immune cell counts of: memory B cells, resting NK cells, M0 macrophages and activated dendritic cells *Some overlap with score development and testing samples
PPM000969 PGS000341
(GRS33_SSc)
PSS000489|
European Ancestry|
339 individuals
PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
Reported Trait: Systemic sclerosis AUROC: 0.722 Systemic sclerosis status and immune cell counts of: memory B cells, resting NK cells, M0 macrophages and activated dendritic cells *Some overlap with score development and testing samples
PPM000968 PGS000341
(GRS33_SSc)
PSS000489|
European Ancestry|
339 individuals
PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
Reported Trait: Systemic sclerosis AUROC: 0.644 *Some overlap with score development and testing samples
PPM000998 PGS000350
(GRS12_POAG)
PSS000513|
European Ancestry|
2,947 individuals
PGP000115 |
Fan BJ et al. JAMA Ophthalmol (2019)
Reported Trait: Primary open-angle glaucoma age at diagnosis β: -0.36 [-0.56, -0.16] sex, DNA source, population structure
PPM000997 PGS000350
(GRS12_POAG)
PSS000512|
European Ancestry|
6,538 individuals
PGP000115 |
Fan BJ et al. JAMA Ophthalmol (2019)
Reported Trait: Primary open-angle glaucoma OR: 1.24 [1.21, 1.27] sex, DNA source, population structure
PPM001302 PGS000617
(PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608)
PSS000556|
European Ancestry|
672 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Cancer of eye OR: 1.339 [1.033, 1.736]
β: 0.292 (0.132)
AUROC: 0.586 [0.508, 0.658] Nagelkerke's Pseudo-R²: 0.0152
Brier score: 0.0831
Odds Ratio (OR, top 1% vs. Rest): 4.74 [1.2, 18.7]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE190_20001-1030_PRS-CS_MGI_20200608
PPM001956 PGS000764
(PRS23_POAG)
PSS000977|
Multi-ancestry (excluding European)|
3,830 individuals
PGP000169 |
Cole BS et al. Invest Ophthalmol Vis Sci (2021)
Reported Trait: Primary-open angle glaucoma Odds Ratio (OR per 1 point increase): 1.08 [1.06, 1.11] Age, ancestry (q0), gender
PPM001957 PGS000764
(PRS23_POAG)
PSS000978|
Multi-ancestry (excluding European)|
2,135 individuals
PGP000169 |
Cole BS et al. Invest Ophthalmol Vis Sci (2021)
Reported Trait: Primary-open angle glaucoma Odds Ratio (OR per 1 point increase): 1.08 [1.05, 1.12] Age, ancestry (q0), gender
PPM002190 PGS000819
(PRS_DR)
PSS001067|
Multi-ancestry (including European)|
6,079 individuals
PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
Reported Trait: Retinal hemorrhage in inidividuals with type 2 diabetes OR: 1.44 [1.03, 2.02]
PPM002185 PGS000819
(PRS_DR)
PSS001067|
Multi-ancestry (including European)|
6,079 individuals
PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
Reported Trait: Diabetic retinopathy in individuals with type 2 diabetes OR: 1.12 [1.04, 1.2]
PPM002186 PGS000819
(PRS_DR)
PSS001066|
European Ancestry|
978 individuals
PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
Reported Trait: Diabetic retinopathy in individuals with type 2 diabetes OR: 1.22 [1.02, 1.41]
PPM002187 PGS000819
(PRS_DR)
PSS001065|
African Ancestry|
1,925 individuals
PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
Reported Trait: Diabetic retinopathy in individuals with type 2 diabetes OR: 1.15 [1.03, 1.28]
PPM002188 PGS000819
(PRS_DR)
PSS001067|
Multi-ancestry (including European)|
6,079 individuals
PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
Reported Trait: Diabetic retinopathy in individuals with type 2 diabetes Odds Ratio (OR, top 10% vs bottom 10%): 1.8 [1.28, 2.55] Age, sex, body mass index, PCs(1-20), history of hypertension, glucose levels
PPM002189 PGS000819
(PRS_DR)
PSS001067|
Multi-ancestry (including European)|
6,079 individuals
PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
Reported Trait: Diabetic retinopathy in individuals with type 2 diabetes OR: 1.14 [1.05, 1.23] PCs(1-20), type 2 diabetes duration, type 2 diabetes medication, hyperglycemia, elevated HbA1c, hypertension, hypercholesterolemia, hyperlipidemia, insomina, sleep apnea, age, sex, body mass index
PPM002191 PGS000819
(PRS_DR)
PSS001067|
Multi-ancestry (including European)|
6,079 individuals
PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
Reported Trait: Diplopia in individuals with type 2 diabetes OR: 1.31 [1.02, 1.7]
PPM002192 PGS000819
(PRS_DR)
PSS001067|
Multi-ancestry (including European)|
6,079 individuals
PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
Reported Trait: Time to diabetic retinopathy diagnosis in individuals with type 2 diabetes HR: 1.13 [1.05, 1.21] Age, sex, body mass index, PCs(1-20), history of hypertension, glucose levels
PPM002393 PGS000862
(DR)
PSS001086|
European Ancestry|
3,194 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Autoimmune Diabetes OR: 0.98 [0.89, 1.08] PC1-10
PPM002395 PGS000862
(DR)
PSS001088|
European Ancestry|
3,869 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Resistant Diabetes OR: 1.09 [1.02, 1.17] PC1-10
PPM002397 PGS000862
(DR)
PSS001084|
European Ancestry|
5,597 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Age-Related Diabetes OR: 1.01 [0.96, 1.07] PC1-10
PPM002394 PGS000862
(DR)
PSS001087|
European Ancestry|
3,930 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Severe Insulin-Deficient Diabetes OR: 1.03 [0.96, 1.1] PC1-10
PPM002396 PGS000862
(DR)
PSS001085|
European Ancestry|
4,116 individuals
PGP000211 |
Aly DM et al. Nat Genet (2021)
Reported Trait: Moderate Obesity-related Diabetes OR: 1.09 [1.02, 1.17] PC1-10
PPM007654 PGS000966
(GBE_HC26)
PSS004399|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Iritis AUROC: 0.92131 [0.81365, 1.0] : 0.11296
Incremental AUROC (full-covars): 0.00359
PGS R2 (no covariates): 0.14006
PGS AUROC (no covariates): 0.66325 [0.33513, 0.99137]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007655 PGS000966
(GBE_HC26)
PSS004400|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Iritis AUROC: 0.79843 [0.66002, 0.93684] : 0.10294
Incremental AUROC (full-covars): 0.06447
PGS R2 (no covariates): 0.09763
PGS AUROC (no covariates): 0.75287 [0.61793, 0.88781]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007656 PGS000966
(GBE_HC26)
PSS004401|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Iritis AUROC: 0.961 [0.92628, 0.99572] : 0.2291
Incremental AUROC (full-covars): -0.00048
PGS R2 (no covariates): 0.00222
PGS AUROC (no covariates): 0.49061 [0.48911, 0.49211]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007657 PGS000966
(GBE_HC26)
PSS004402|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Iritis AUROC: 0.77646 [0.69039, 0.86254] : 0.08068
Incremental AUROC (full-covars): 0.22055
PGS R2 (no covariates): 0.10834
PGS AUROC (no covariates): 0.78582 [0.71071, 0.86092]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007718 PGS000990
(GBE_HC878)
PSS004682|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal detachments and breaks AUROC: 0.61927 [0.54935, 0.68918] : 0.0247
Incremental AUROC (full-covars): -0.01882
PGS R2 (no covariates): 0.00198
PGS AUROC (no covariates): 0.46633 [0.38893, 0.54373]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007719 PGS000990
(GBE_HC878)
PSS004683|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal detachments and breaks AUROC: 0.75788 [0.63933, 0.87643] : 0.10693
Incremental AUROC (full-covars): 0.0196
PGS R2 (no covariates): 0.01417
PGS AUROC (no covariates): 0.5954 [0.44975, 0.74105]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007720 PGS000990
(GBE_HC878)
PSS004684|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal detachments and breaks AUROC: 0.64308 [0.61279, 0.67337] : 0.02565
Incremental AUROC (full-covars): 0.00606
PGS R2 (no covariates): 0.00213
PGS AUROC (no covariates): 0.54152 [0.50847, 0.57457]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007721 PGS000990
(GBE_HC878)
PSS004685|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal detachments and breaks AUROC: 0.71433 [0.66221, 0.76646] : 0.05371
Incremental AUROC (full-covars): 0.0098
PGS R2 (no covariates): 0.00492
PGS AUROC (no covariates): 0.56225 [0.49739, 0.62711]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007722 PGS000990
(GBE_HC878)
PSS004686|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal detachments and breaks AUROC: 0.63532 [0.61784, 0.65279] : 0.02226
Incremental AUROC (full-covars): 0.00479
PGS R2 (no covariates): 0.00207
PGS AUROC (no covariates): 0.53945 [0.52027, 0.55863]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007828 PGS001013
(GBE_BIN_FC5006148)
PSS003974|
African Ancestry|
3,196 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Macular degeneration AUROC: 0.7052 [0.63504, 0.77537] : 0.07369
Incremental AUROC (full-covars): -0.00271
PGS R2 (no covariates): 6e-05
PGS AUROC (no covariates): 0.50582 [0.43466, 0.57699]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007829 PGS001013
(GBE_BIN_FC5006148)
PSS003975|
East Asian Ancestry|
711 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Macular degeneration AUROC: 0.90123 [0.8354, 0.96707] : 0.32752
Incremental AUROC (full-covars): -0.00016
PGS R2 (no covariates): 0.01068
PGS AUROC (no covariates): 0.59339 [0.45683, 0.72996]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007830 PGS001013
(GBE_BIN_FC5006148)
PSS003976|
European Ancestry|
9,755 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Macular degeneration AUROC: 0.72878 [0.69745, 0.76011] : 0.07729
Incremental AUROC (full-covars): 0.00516
PGS R2 (no covariates): 0.00265
PGS AUROC (no covariates): 0.53845 [0.49847, 0.57843]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007831 PGS001013
(GBE_BIN_FC5006148)
PSS003977|
South Asian Ancestry|
3,327 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Macular degeneration AUROC: 0.76624 [0.71098, 0.8215] : 0.10324
Incremental AUROC (full-covars): -0.00396
PGS R2 (no covariates): 0.00053
PGS AUROC (no covariates): 0.47169 [0.39626, 0.54712]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007832 PGS001013
(GBE_BIN_FC5006148)
PSS003978|
European Ancestry|
22,208 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Macular degeneration AUROC: 0.70257 [0.6826, 0.72253] : 0.06704
Incremental AUROC (full-covars): 0.00573
PGS R2 (no covariates): 0.00599
PGS AUROC (no covariates): 0.55283 [0.52939, 0.57627]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007903 PGS001028
(GBE_BIN_FC1006148)
PSS003765|
African Ancestry|
3,307 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Diabetic eye disease AUROC: 0.76275 [0.72796, 0.79755] : 0.13906
Incremental AUROC (full-covars): 0.0014
PGS R2 (no covariates): 0.00197
PGS AUROC (no covariates): 0.53892 [0.49569, 0.58215]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007904 PGS001028
(GBE_BIN_FC1006148)
PSS003766|
East Asian Ancestry|
706 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Diabetic eye disease AUROC: 0.83123 [0.71584, 0.94663] : 0.24524
Incremental AUROC (full-covars): -0.00599
PGS R2 (no covariates): 0.0016
PGS AUROC (no covariates): 0.44953 [0.27083, 0.62822]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007905 PGS001028
(GBE_BIN_FC1006148)
PSS003767|
European Ancestry|
9,719 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Diabetic eye disease AUROC: 0.69201 [0.65353, 0.73049] : 0.05584
Incremental AUROC (full-covars): 0.01974
PGS R2 (no covariates): 0.01281
PGS AUROC (no covariates): 0.5903 [0.54859, 0.632]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007906 PGS001028
(GBE_BIN_FC1006148)
PSS003768|
South Asian Ancestry|
3,533 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Diabetic eye disease AUROC: 0.7302 [0.69952, 0.76088] : 0.11745
Incremental AUROC (full-covars): 0.002
PGS R2 (no covariates): 0.00272
PGS AUROC (no covariates): 0.53803 [0.50292, 0.57313]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007907 PGS001028
(GBE_BIN_FC1006148)
PSS003769|
European Ancestry|
22,053 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Diabetic eye disease AUROC: 0.69853 [0.67583, 0.72122] : 0.05279
Incremental AUROC (full-covars): 0.01792
PGS R2 (no covariates): 0.00926
PGS AUROC (no covariates): 0.57814 [0.55078, 0.6055]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007908 PGS001029
(GBE_HC866)
PSS004662|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other disorders of cornea AUROC: 0.71052 [0.62918, 0.79186] : 0.05427
Incremental AUROC (full-covars): 0.0031
PGS R2 (no covariates): 0.00332
PGS AUROC (no covariates): 0.54756 [0.45415, 0.64098]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007909 PGS001029
(GBE_HC866)
PSS004663|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other disorders of cornea AUROC: 0.48912 [0.0043, 0.97395] : 0.00203
Incremental AUROC (full-covars): 0.0
PGS R2 (no covariates): 0.00633
PGS AUROC (no covariates): 0.40016 [0.0, 0.86755]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007910 PGS001029
(GBE_HC866)
PSS004664|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other disorders of cornea AUROC: 0.63469 [0.57721, 0.69216] : 0.01902
Incremental AUROC (full-covars): 0.04837
PGS R2 (no covariates): 0.01229
PGS AUROC (no covariates): 0.59818 [0.5417, 0.65467]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007911 PGS001029
(GBE_HC866)
PSS004665|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other disorders of cornea AUROC: 0.62122 [0.5586, 0.68385] : 0.02027
Incremental AUROC (full-covars): -0.01924
PGS R2 (no covariates): 0.00532
PGS AUROC (no covariates): 0.44761 [0.382, 0.51322]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007912 PGS001029
(GBE_HC866)
PSS004666|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other disorders of cornea AUROC: 0.60075 [0.56985, 0.63165] : 0.01227
Incremental AUROC (full-covars): 0.02429
PGS R2 (no covariates): 0.00807
PGS AUROC (no covariates): 0.58115 [0.55051, 0.61178]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008412 PGS001137
(GBE_HC302)
PSS004418|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Retinal detachment AUROC: 0.65217 [0.57926, 0.72508] : 0.03407
Incremental AUROC (full-covars): -0.00918
PGS R2 (no covariates): 1e-05
PGS AUROC (no covariates): 0.49921 [0.41839, 0.58004]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008413 PGS001137
(GBE_HC302)
PSS004419|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Retinal detachment AUROC: 0.7872 [0.68424, 0.89016] : 0.13209
Incremental AUROC (full-covars): 0.01471
PGS R2 (no covariates): 0.00931
PGS AUROC (no covariates): 0.57064 [0.39309, 0.74819]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008414 PGS001137
(GBE_HC302)
PSS004420|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Retinal detachment AUROC: 0.65311 [0.62153, 0.68468] : 0.02791
Incremental AUROC (full-covars): 0.01854
PGS R2 (no covariates): 0.00663
PGS AUROC (no covariates): 0.57317 [0.53771, 0.60862]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008415 PGS001137
(GBE_HC302)
PSS004421|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Retinal detachment AUROC: 0.73537 [0.67789, 0.79285] : 0.0635
Incremental AUROC (full-covars): 0.01358
PGS R2 (no covariates): 0.00738
PGS AUROC (no covariates): 0.55915 [0.48569, 0.63261]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008416 PGS001137
(GBE_HC302)
PSS004422|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Retinal detachment AUROC: 0.63847 [0.61945, 0.65749] : 0.02286
Incremental AUROC (full-covars): 0.00912
PGS R2 (no covariates): 0.00357
PGS AUROC (no covariates): 0.55079 [0.52979, 0.57179]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008873 PGS001275
(GBE_HC880)
PSS004687|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other retinal disorders AUROC: 0.70701 [0.6592, 0.75482] : 0.06654
Incremental AUROC (full-covars): -0.00077
PGS R2 (no covariates): 0.00011
PGS AUROC (no covariates): 0.50886 [0.45807, 0.55965]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008874 PGS001275
(GBE_HC880)
PSS004688|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other retinal disorders AUROC: 0.76408 [0.70187, 0.8263] : 0.11034
Incremental AUROC (full-covars): 0.00238
PGS R2 (no covariates): 0.00124
PGS AUROC (no covariates): 0.54196 [0.45417, 0.62976]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008875 PGS001275
(GBE_HC880)
PSS004689|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other retinal disorders AUROC: 0.68838 [0.66508, 0.71167] : 0.04946
Incremental AUROC (full-covars): 0.00295
PGS R2 (no covariates): 0.00217
PGS AUROC (no covariates): 0.53609 [0.50994, 0.56223]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008876 PGS001275
(GBE_HC880)
PSS004690|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other retinal disorders AUROC: 0.73994 [0.71282, 0.76707] : 0.09449
Incremental AUROC (full-covars): 0.00101
PGS R2 (no covariates): 0.00053
PGS AUROC (no covariates): 0.51345 [0.47882, 0.54808]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008877 PGS001275
(GBE_HC880)
PSS004691|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other retinal disorders AUROC: 0.67575 [0.6628, 0.6887] : 0.04416
Incremental AUROC (full-covars): 0.00229
PGS R2 (no covariates): 0.00203
PGS AUROC (no covariates): 0.53038 [0.51532, 0.54545]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008878 PGS001276
(GBE_HC881)
PSS004692|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal disorders in diseases classified elsewhere AUROC: 0.69535 [0.65164, 0.73906] : 0.04898
Incremental AUROC (full-covars): -0.01537
PGS R2 (no covariates): 0.00048
PGS AUROC (no covariates): 0.47863 [0.42888, 0.52839]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008879 PGS001276
(GBE_HC881)
PSS004693|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal disorders in diseases classified elsewhere AUROC: 0.78112 [0.63575, 0.92649] : 0.09795
Incremental AUROC (full-covars): -0.03107
PGS R2 (no covariates): 0.00124
PGS AUROC (no covariates): 0.45159 [0.20305, 0.70013]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008880 PGS001276
(GBE_HC881)
PSS004694|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal disorders in diseases classified elsewhere AUROC: 0.70588 [0.66187, 0.7499] : 0.04864
Incremental AUROC (full-covars): 0.02939
PGS R2 (no covariates): 0.01461
PGS AUROC (no covariates): 0.60872 [0.55828, 0.65917]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008881 PGS001276
(GBE_HC881)
PSS004695|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal disorders in diseases classified elsewhere AUROC: 0.73414 [0.70226, 0.76602] : 0.08369
Incremental AUROC (full-covars): -7e-05
PGS R2 (no covariates): 0.00183
PGS AUROC (no covariates): 0.53682 [0.49711, 0.57653]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008882 PGS001276
(GBE_HC881)
PSS004696|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE retinal disorders in diseases classified elsewhere AUROC: 0.67399 [0.64743, 0.70056] : 0.03213
Incremental AUROC (full-covars): 0.02207
PGS R2 (no covariates): 0.00817
PGS AUROC (no covariates): 0.57664 [0.54625, 0.60704]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009005 PGS001302
(GBE_HC25)
PSS004379|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Cataract AUROC: 0.81842 [0.80148, 0.83536] : 0.25176
Incremental AUROC (full-covars): -0.00057
PGS R2 (no covariates): 0.00041
PGS AUROC (no covariates): 0.51203 [0.48858, 0.53548]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009006 PGS001302
(GBE_HC25)
PSS004380|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Cataract AUROC: 0.81531 [0.78353, 0.84709] : 0.22081
Incremental AUROC (full-covars): 0.00025
PGS R2 (no covariates): 0.00037
PGS AUROC (no covariates): 0.48894 [0.43818, 0.53971]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009007 PGS001302
(GBE_HC25)
PSS004381|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Cataract AUROC: 0.76448 [0.75374, 0.77523] : 0.14636
Incremental AUROC (full-covars): 0.00517
PGS R2 (no covariates): 0.00768
PGS AUROC (no covariates): 0.56031 [0.5466, 0.57402]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009008 PGS001302
(GBE_HC25)
PSS004382|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Cataract AUROC: 0.81674 [0.80411, 0.82937] : 0.28207
Incremental AUROC (full-covars): 0.0031
PGS R2 (no covariates): 0.00627
PGS AUROC (no covariates): 0.54731 [0.52945, 0.56518]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009009 PGS001302
(GBE_HC25)
PSS004383|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Cataract AUROC: 0.73692 [0.73039, 0.74345] : 0.12068
Incremental AUROC (full-covars): 0.00566
PGS R2 (no covariates): 0.00657
PGS AUROC (no covariates): 0.55468 [0.5465, 0.56286]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009010 PGS001303
(GBE_HC872)
PSS004677|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other cataract AUROC: 0.81396 [0.7961, 0.83182] : 0.23163
Incremental AUROC (full-covars): 5e-05
PGS R2 (no covariates): 0.00013
PGS AUROC (no covariates): 0.50326 [0.47798, 0.52854]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009011 PGS001303
(GBE_HC872)
PSS004678|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other cataract AUROC: 0.81597 [0.77997, 0.85198] : 0.21513
Incremental AUROC (full-covars): 0.00031
PGS R2 (no covariates): 0.00012
PGS AUROC (no covariates): 0.50879 [0.45096, 0.56661]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009012 PGS001303
(GBE_HC872)
PSS004679|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other cataract AUROC: 0.75268 [0.74071, 0.76465] : 0.12486
Incremental AUROC (full-covars): 0.00345
PGS R2 (no covariates): 0.00455
PGS AUROC (no covariates): 0.5485 [0.53327, 0.56373]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009013 PGS001303
(GBE_HC872)
PSS004680|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other cataract AUROC: 0.79821 [0.78425, 0.81216] : 0.23261
Incremental AUROC (full-covars): 0.00152
PGS R2 (no covariates): 0.00238
PGS AUROC (no covariates): 0.52897 [0.51011, 0.54783]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009014 PGS001303
(GBE_HC872)
PSS004681|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE other cataract AUROC: 0.72387 [0.71653, 0.73121] : 0.09993
Incremental AUROC (full-covars): 0.00356
PGS R2 (no covariates): 0.0043
PGS AUROC (no covariates): 0.54593 [0.53685, 0.555]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009034 PGS001308
(GBE_HC321)
PSS004437|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sjogren's syndrome/sicca syndrome AUROC: 0.79846 [0.71474, 0.88218] : 0.07345
Incremental AUROC (full-covars): 0.0079
PGS R2 (no covariates): 0.01471
PGS AUROC (no covariates): 0.59027 [0.45551, 0.72504]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009035 PGS001308
(GBE_HC321)
PSS004438|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sjogren's syndrome/sicca syndrome AUROC: 0.75824 [0.55089, 0.96558] : 0.05686
Incremental AUROC (full-covars): 0.00691
PGS R2 (no covariates): 0.0091
PGS AUROC (no covariates): 0.69794 [0.63241, 0.76347]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009036 PGS001308
(GBE_HC321)
PSS004439|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sjogren's syndrome/sicca syndrome AUROC: 0.77174 [0.71988, 0.82361] : 0.07435
Incremental AUROC (full-covars): 0.01461
PGS R2 (no covariates): 0.01453
PGS AUROC (no covariates): 0.65693 [0.58901, 0.72485]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009037 PGS001308
(GBE_HC321)
PSS004440|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sjogren's syndrome/sicca syndrome AUROC: 0.8014 [0.74455, 0.85826] : 0.08893
Incremental AUROC (full-covars): 0.00953
PGS R2 (no covariates): 0.03189
PGS AUROC (no covariates): 0.61034 [0.48809, 0.73259]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009038 PGS001308
(GBE_HC321)
PSS004441|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sjogren's syndrome/sicca syndrome AUROC: 0.73313 [0.69647, 0.76978] : 0.04771
Incremental AUROC (full-covars): 0.01551
PGS R2 (no covariates): 0.01074
PGS AUROC (no covariates): 0.60303 [0.55292, 0.65315]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009097 PGS001321
(GBE_BIN_FC2006148)
PSS003849|
African Ancestry|
3,341 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Glaucoma AUROC: 0.75589 [0.72234, 0.78943] : 0.13943
Incremental AUROC (full-covars): -0.01209
PGS R2 (no covariates): 1e-05
PGS AUROC (no covariates): 0.49958 [0.46126, 0.5379]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009098 PGS001321
(GBE_BIN_FC2006148)
PSS003850|
East Asian Ancestry|
715 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Glaucoma AUROC: 0.71808 [0.61808, 0.81809] : 0.09844
Incremental AUROC (full-covars): -0.01728
PGS R2 (no covariates): 0.00057
PGS AUROC (no covariates): 0.5191 [0.40156, 0.63664]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009099 PGS001321
(GBE_BIN_FC2006148)
PSS003851|
European Ancestry|
9,888 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Glaucoma AUROC: 0.75377 [0.72896, 0.77858] : 0.11288
Incremental AUROC (full-covars): 0.01096
PGS R2 (no covariates): 0.01038
PGS AUROC (no covariates): 0.57925 [0.54955, 0.60894]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009100 PGS001321
(GBE_BIN_FC2006148)
PSS003852|
South Asian Ancestry|
3,441 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Glaucoma AUROC: 0.7617 [0.72794, 0.79547] : 0.1335
Incremental AUROC (full-covars): 0.00638
PGS R2 (no covariates): 0.01082
PGS AUROC (no covariates): 0.57361 [0.5321, 0.61512]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009101 PGS001321
(GBE_BIN_FC2006148)
PSS003853|
European Ancestry|
22,623 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Eye problems/disorders Glaucoma AUROC: 0.72434 [0.70924, 0.73944] : 0.09306
Incremental AUROC (full-covars): 0.02225
PGS R2 (no covariates): 0.0194
PGS AUROC (no covariates): 0.60001 [0.58198, 0.61804]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009102 PGS001322
(GBE_HC276)
PSS004408|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Glaucoma AUROC: 0.73888 [0.70843, 0.76932] : 0.0999
Incremental AUROC (full-covars): -0.00815
PGS R2 (no covariates): 0.00019
PGS AUROC (no covariates): 0.48469 [0.45088, 0.5185]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009103 PGS001322
(GBE_HC276)
PSS004409|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Glaucoma AUROC: 0.70681 [0.61243, 0.80118] : 0.05552
Incremental AUROC (full-covars): -0.01374
PGS R2 (no covariates): 0.00272
PGS AUROC (no covariates): 0.45399 [0.34399, 0.564]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009104 PGS001322
(GBE_HC276)
PSS004410|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Glaucoma AUROC: 0.73317 [0.71252, 0.75382] : 0.0763
Incremental AUROC (full-covars): 0.01834
PGS R2 (no covariates): 0.01238
PGS AUROC (no covariates): 0.59932 [0.57386, 0.62477]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009105 PGS001322
(GBE_HC276)
PSS004411|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Glaucoma AUROC: 0.74918 [0.71835, 0.78] : 0.09545
Incremental AUROC (full-covars): 0.01096
PGS R2 (no covariates): 0.01142
PGS AUROC (no covariates): 0.59951 [0.56169, 0.63734]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009106 PGS001322
(GBE_HC276)
PSS004412|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Glaucoma AUROC: 0.7048 [0.69206, 0.71754] : 0.0589
Incremental AUROC (full-covars): 0.02562
PGS R2 (no covariates): 0.015
PGS AUROC (no covariates): 0.60261 [0.58762, 0.6176]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009107 PGS001323
(GBE_HC882)
PSS004697|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE glaucoma AUROC: 0.72181 [0.69233, 0.75129] : 0.0918
Incremental AUROC (full-covars): -0.00164
PGS R2 (no covariates): 0.00184
PGS AUROC (no covariates): 0.53284 [0.50004, 0.56563]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009108 PGS001323
(GBE_HC882)
PSS004698|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE glaucoma AUROC: 0.70826 [0.61816, 0.79836] : 0.06483
Incremental AUROC (full-covars): 0.01999
PGS R2 (no covariates): 0.00405
PGS AUROC (no covariates): 0.54496 [0.43191, 0.65802]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009109 PGS001323
(GBE_HC882)
PSS004699|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE glaucoma AUROC: 0.72679 [0.7079, 0.74569] : 0.07732
Incremental AUROC (full-covars): 0.0269
PGS R2 (no covariates): 0.01761
PGS AUROC (no covariates): 0.60838 [0.58579, 0.63096]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009110 PGS001323
(GBE_HC882)
PSS004700|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE glaucoma AUROC: 0.73399 [0.70517, 0.76282] : 0.08727
Incremental AUROC (full-covars): 0.00993
PGS R2 (no covariates): 0.00928
PGS AUROC (no covariates): 0.57629 [0.54141, 0.61116]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009111 PGS001323
(GBE_HC882)
PSS004701|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: TTE glaucoma AUROC: 0.70422 [0.69334, 0.7151] : 0.06469
Incremental AUROC (full-covars): 0.0364
PGS R2 (no covariates): 0.02201
PGS AUROC (no covariates): 0.61994 [0.60732, 0.63256]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009452 PGS001819
(portability-PLR_250.7)
PSS009289|
European Ancestry|
19,330 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0366 [0.0226, 0.0507] sex, age, birth date, deprivation index, 16 PCs
PPM009453 PGS001819
(portability-PLR_250.7)
PSS009063|
European Ancestry|
4,032 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0638 [0.033, 0.0946] sex, age, birth date, deprivation index, 16 PCs
PPM009454 PGS001819
(portability-PLR_250.7)
PSS008617|
European Ancestry|
6,465 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0315 [0.0071, 0.0559] sex, age, birth date, deprivation index, 16 PCs
PPM009455 PGS001819
(portability-PLR_250.7)
PSS008393|
Greater Middle Eastern Ancestry|
1,162 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): -0.0471 [-0.1048, 0.011] sex, age, birth date, deprivation index, 16 PCs
PPM009456 PGS001819
(portability-PLR_250.7)
PSS008171|
South Asian Ancestry|
6,081 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0325 [0.0074, 0.0577] sex, age, birth date, deprivation index, 16 PCs
PPM009457 PGS001819
(portability-PLR_250.7)
PSS007958|
East Asian Ancestry|
1,764 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): -0.0249 [-0.0718, 0.022] sex, age, birth date, deprivation index, 16 PCs
PPM009459 PGS001819
(portability-PLR_250.7)
PSS008842|
African Ancestry|
3,732 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0089 [-0.0233, 0.041] sex, age, birth date, deprivation index, 16 PCs
PPM009458 PGS001819
(portability-PLR_250.7)
PSS007739|
African Ancestry|
2,385 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): -0.0193 [-0.0596, 0.021] sex, age, birth date, deprivation index, 16 PCs
PPM009556 PGS001833
(portability-PLR_361)
PSS009303|
European Ancestry|
19,445 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0218 [0.0078, 0.0359] sex, age, birth date, deprivation index, 16 PCs
PPM009557 PGS001833
(portability-PLR_361)
PSS009077|
European Ancestry|
4,055 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0304 sex, age, birth date, deprivation index, 16 PCs
PPM009558 PGS001833
(portability-PLR_361)
PSS008631|
European Ancestry|
6,514 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0086 [-0.0157, 0.0329] sex, age, birth date, deprivation index, 16 PCs
PPM009559 PGS001833
(portability-PLR_361)
PSS008405|
Greater Middle Eastern Ancestry|
1,169 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): -0.0283 [-0.086, 0.0296] sex, age, birth date, deprivation index, 16 PCs
PPM009560 PGS001833
(portability-PLR_361)
PSS008185|
South Asian Ancestry|
6,095 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0155 [-0.0096, 0.0406] sex, age, birth date, deprivation index, 16 PCs
PPM009561 PGS001833
(portability-PLR_361)
PSS007969|
East Asian Ancestry|
1,773 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0326 [-0.0142, 0.0793] sex, age, birth date, deprivation index, 16 PCs
PPM009562 PGS001833
(portability-PLR_361)
PSS007751|
African Ancestry|
2,384 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0172 [-0.0231, 0.0575] sex, age, birth date, deprivation index, 16 PCs
PPM009563 PGS001833
(portability-PLR_361)
PSS008855|
African Ancestry|
3,743 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.012 [-0.0201, 0.0441] sex, age, birth date, deprivation index, 16 PCs
PPM009565 PGS001834
(portability-PLR_362.29)
PSS009078|
European Ancestry|
4,043 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0258 [-0.0051, 0.0567] sex, age, birth date, deprivation index, 16 PCs
PPM009566 PGS001834
(portability-PLR_362.29)
PSS008632|
European Ancestry|
6,470 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0177 [-0.0067, 0.0421] sex, age, birth date, deprivation index, 16 PCs
PPM009567 PGS001834
(portability-PLR_362.29)
PSS008406|
Greater Middle Eastern Ancestry|
1,165 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): -0.03 [-0.0877, 0.028] sex, age, birth date, deprivation index, 16 PCs
PPM009568 PGS001834
(portability-PLR_362.29)
PSS008186|
South Asian Ancestry|
6,037 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0368 [0.0116, 0.062] sex, age, birth date, deprivation index, 16 PCs
PPM009569 PGS001834
(portability-PLR_362.29)
PSS007970|
East Asian Ancestry|
1,775 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): -0.0304 [-0.0771, 0.0164] sex, age, birth date, deprivation index, 16 PCs
PPM009570 PGS001834
(portability-PLR_362.29)
PSS007752|
African Ancestry|
2,374 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0015 [-0.0389, 0.0419] sex, age, birth date, deprivation index, 16 PCs
PPM009571 PGS001834
(portability-PLR_362.29)
PSS008856|
African Ancestry|
3,723 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0144 [-0.0178, 0.0466] sex, age, birth date, deprivation index, 16 PCs
PPM009564 PGS001834
(portability-PLR_362.29)
PSS009304|
European Ancestry|
19,413 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0175 [0.0034, 0.0315] sex, age, birth date, deprivation index, 16 PCs
PPM009572 PGS001835
(portability-PLR_364.5)
PSS009305|
European Ancestry|
19,321 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): 0.0384 [0.0243, 0.0525] sex, age, birth date, deprivation index, 16 PCs
PPM009573 PGS001835
(portability-PLR_364.5)
PSS009079|
European Ancestry|
4,029 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): 0.0753 [0.0445, 0.106] sex, age, birth date, deprivation index, 16 PCs
PPM009574 PGS001835
(portability-PLR_364.5)
PSS008633|
European Ancestry|
6,462 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): 0.0488 [0.0245, 0.0732] sex, age, birth date, deprivation index, 16 PCs
PPM009575 PGS001835
(portability-PLR_364.5)
PSS008407|
Greater Middle Eastern Ancestry|
1,162 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): 0.0128 [-0.0452, 0.0708] sex, age, birth date, deprivation index, 16 PCs
PPM009577 PGS001835
(portability-PLR_364.5)
PSS008857|
African Ancestry|
3,718 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): -0.0168 [-0.049, 0.0155] sex, age, birth date, deprivation index, 16 PCs
PPM009576 PGS001835
(portability-PLR_364.5)
PSS008187|
South Asian Ancestry|
6,052 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): -0.011 [-0.0362, 0.0143] sex, age, birth date, deprivation index, 16 PCs
PPM009578 PGS001836
(portability-PLR_365)
PSS009306|
European Ancestry|
19,592 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0419 [0.0279, 0.0558] sex, age, birth date, deprivation index, 16 PCs
PPM009579 PGS001836
(portability-PLR_365)
PSS009080|
European Ancestry|
4,066 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0404 [0.0096, 0.0711] sex, age, birth date, deprivation index, 16 PCs
PPM009580 PGS001836
(portability-PLR_365)
PSS008634|
European Ancestry|
6,540 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0301 [0.0059, 0.0544] sex, age, birth date, deprivation index, 16 PCs
PPM009581 PGS001836
(portability-PLR_365)
PSS008408|
Greater Middle Eastern Ancestry|
1,181 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0631 [0.0056, 0.1202] sex, age, birth date, deprivation index, 16 PCs
PPM009582 PGS001836
(portability-PLR_365)
PSS008188|
South Asian Ancestry|
6,176 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0232 [-0.0018, 0.0481] sex, age, birth date, deprivation index, 16 PCs
PPM009583 PGS001836
(portability-PLR_365)
PSS007971|
East Asian Ancestry|
1,783 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0002 [-0.0465, 0.0469] sex, age, birth date, deprivation index, 16 PCs
PPM009584 PGS001836
(portability-PLR_365)
PSS007753|
African Ancestry|
2,447 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0282 [-0.0116, 0.0679] sex, age, birth date, deprivation index, 16 PCs
PPM009585 PGS001836
(portability-PLR_365)
PSS008858|
African Ancestry|
3,854 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0257 [-0.0059, 0.0573] sex, age, birth date, deprivation index, 16 PCs
PPM009587 PGS001837
(portability-PLR_366)
PSS009081|
European Ancestry|
4,136 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0813 [0.0508, 0.1115] sex, age, birth date, deprivation index, 16 PCs
PPM009588 PGS001837
(portability-PLR_366)
PSS008635|
European Ancestry|
6,660 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0642 [0.0402, 0.0881] sex, age, birth date, deprivation index, 16 PCs
PPM009589 PGS001837
(portability-PLR_366)
PSS008409|
Greater Middle Eastern Ancestry|
1,200 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0028 [-0.0543, 0.0598] sex, age, birth date, deprivation index, 16 PCs
PPM009590 PGS001837
(portability-PLR_366)
PSS008189|
South Asian Ancestry|
6,331 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.078 [0.0534, 0.1025] sex, age, birth date, deprivation index, 16 PCs
PPM009591 PGS001837
(portability-PLR_366)
PSS007972|
East Asian Ancestry|
1,810 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0018 [-0.0445, 0.0482] sex, age, birth date, deprivation index, 16 PCs
PPM009592 PGS001837
(portability-PLR_366)
PSS007754|
African Ancestry|
2,484 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): -0.0371 [-0.0765, 0.0023] sex, age, birth date, deprivation index, 16 PCs
PPM009593 PGS001837
(portability-PLR_366)
PSS008859|
African Ancestry|
3,924 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0161 [-0.0153, 0.0474] sex, age, birth date, deprivation index, 16 PCs
PPM009586 PGS001837
(portability-PLR_366)
PSS009307|
European Ancestry|
20,000 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0436 [0.0297, 0.0574] sex, age, birth date, deprivation index, 16 PCs
PPM011090 PGS002027
(portability-ldpred2_250.7)
PSS009289|
European Ancestry|
19,330 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0451 [0.031, 0.0592] sex, age, birth date, deprivation index, 16 PCs
PPM011091 PGS002027
(portability-ldpred2_250.7)
PSS009063|
European Ancestry|
4,032 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0607 [0.0298, 0.0915] sex, age, birth date, deprivation index, 16 PCs
PPM011092 PGS002027
(portability-ldpred2_250.7)
PSS008617|
European Ancestry|
6,465 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0241 sex, age, birth date, deprivation index, 16 PCs
PPM011093 PGS002027
(portability-ldpred2_250.7)
PSS008393|
Greater Middle Eastern Ancestry|
1,162 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): -0.0311 [-0.0889, 0.027] sex, age, birth date, deprivation index, 16 PCs
PPM011094 PGS002027
(portability-ldpred2_250.7)
PSS008171|
South Asian Ancestry|
6,081 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0351 [0.01, 0.0603] sex, age, birth date, deprivation index, 16 PCs
PPM011095 PGS002027
(portability-ldpred2_250.7)
PSS007958|
East Asian Ancestry|
1,764 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): -0.0302 [-0.077, 0.0168] sex, age, birth date, deprivation index, 16 PCs
PPM011096 PGS002027
(portability-ldpred2_250.7)
PSS007739|
African Ancestry|
2,385 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): -0.0204 [-0.0606, 0.0199] sex, age, birth date, deprivation index, 16 PCs
PPM011097 PGS002027
(portability-ldpred2_250.7)
PSS008842|
African Ancestry|
3,732 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Diabetic retinopathy Partial Correlation (partial-r): 0.0062 [-0.0259, 0.0384] sex, age, birth date, deprivation index, 16 PCs
PPM011186 PGS002040
(portability-ldpred2_361)
PSS009303|
European Ancestry|
19,445 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0276 [0.0135, 0.0416] sex, age, birth date, deprivation index, 16 PCs
PPM011187 PGS002040
(portability-ldpred2_361)
PSS009077|
European Ancestry|
4,055 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0184 [-0.0125, 0.0492] sex, age, birth date, deprivation index, 16 PCs
PPM011188 PGS002040
(portability-ldpred2_361)
PSS008631|
European Ancestry|
6,514 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0125 [-0.0119, 0.0368] sex, age, birth date, deprivation index, 16 PCs
PPM011189 PGS002040
(portability-ldpred2_361)
PSS008405|
Greater Middle Eastern Ancestry|
1,169 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): -0.0028 [-0.0607, 0.055] sex, age, birth date, deprivation index, 16 PCs
PPM011190 PGS002040
(portability-ldpred2_361)
PSS008185|
South Asian Ancestry|
6,095 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0276 [0.0024, 0.0527] sex, age, birth date, deprivation index, 16 PCs
PPM011191 PGS002040
(portability-ldpred2_361)
PSS007969|
East Asian Ancestry|
1,773 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0368 [-0.0101, 0.0835] sex, age, birth date, deprivation index, 16 PCs
PPM011192 PGS002040
(portability-ldpred2_361)
PSS007751|
African Ancestry|
2,384 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0222 [-0.0181, 0.0625] sex, age, birth date, deprivation index, 16 PCs
PPM011193 PGS002040
(portability-ldpred2_361)
PSS008855|
African Ancestry|
3,743 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Retinal detachments and defects Partial Correlation (partial-r): 0.0024 [-0.0297, 0.0345] sex, age, birth date, deprivation index, 16 PCs
PPM011195 PGS002041
(portability-ldpred2_362.29)
PSS009078|
European Ancestry|
4,043 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0248 [-0.0061, 0.0556] sex, age, birth date, deprivation index, 16 PCs
PPM011196 PGS002041
(portability-ldpred2_362.29)
PSS008632|
European Ancestry|
6,470 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0179 [-0.0065, 0.0423] sex, age, birth date, deprivation index, 16 PCs
PPM011197 PGS002041
(portability-ldpred2_362.29)
PSS008406|
Greater Middle Eastern Ancestry|
1,165 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): -0.0344 [-0.0921, 0.0236] sex, age, birth date, deprivation index, 16 PCs
PPM011198 PGS002041
(portability-ldpred2_362.29)
PSS008186|
South Asian Ancestry|
6,037 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0372 [0.0119, 0.0624] sex, age, birth date, deprivation index, 16 PCs
PPM011199 PGS002041
(portability-ldpred2_362.29)
PSS007970|
East Asian Ancestry|
1,775 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): -0.0312 [-0.0779, 0.0156] sex, age, birth date, deprivation index, 16 PCs
PPM011200 PGS002041
(portability-ldpred2_362.29)
PSS007752|
African Ancestry|
2,374 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0038 [-0.0366, 0.0442] sex, age, birth date, deprivation index, 16 PCs
PPM011201 PGS002041
(portability-ldpred2_362.29)
PSS008856|
African Ancestry|
3,723 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.018 [-0.0143, 0.0501] sex, age, birth date, deprivation index, 16 PCs
PPM011194 PGS002041
(portability-ldpred2_362.29)
PSS009304|
European Ancestry|
19,413 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Macular degeneration (senile) of retina NOS Partial Correlation (partial-r): 0.0159 [0.0018, 0.0299] sex, age, birth date, deprivation index, 16 PCs
PPM011202 PGS002042
(portability-ldpred2_364.5)
PSS009305|
European Ancestry|
19,321 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): 0.0471 [0.033, 0.0611] sex, age, birth date, deprivation index, 16 PCs
PPM011203 PGS002042
(portability-ldpred2_364.5)
PSS009079|
European Ancestry|
4,029 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): 0.0812 [0.0504, 0.1119] sex, age, birth date, deprivation index, 16 PCs
PPM011204 PGS002042
(portability-ldpred2_364.5)
PSS008633|
European Ancestry|
6,462 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): 0.0519 [0.0275, 0.0762] sex, age, birth date, deprivation index, 16 PCs
PPM011205 PGS002042
(portability-ldpred2_364.5)
PSS008407|
Greater Middle Eastern Ancestry|
1,162 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): 0.0275 [-0.0306, 0.0853] sex, age, birth date, deprivation index, 16 PCs
PPM011206 PGS002042
(portability-ldpred2_364.5)
PSS008187|
South Asian Ancestry|
6,052 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): -0.0133 [-0.0385, 0.0119] sex, age, birth date, deprivation index, 16 PCs
PPM011207 PGS002042
(portability-ldpred2_364.5)
PSS008857|
African Ancestry|
3,718 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Corneal dystrophy Partial Correlation (partial-r): -0.0084 [-0.0406, 0.0238] sex, age, birth date, deprivation index, 16 PCs
PPM011208 PGS002043
(portability-ldpred2_365)
PSS009306|
European Ancestry|
19,592 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0458 [0.0318, 0.0598] sex, age, birth date, deprivation index, 16 PCs
PPM011209 PGS002043
(portability-ldpred2_365)
PSS009080|
European Ancestry|
4,066 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0458 [0.015, 0.0765] sex, age, birth date, deprivation index, 16 PCs
PPM011211 PGS002043
(portability-ldpred2_365)
PSS008408|
Greater Middle Eastern Ancestry|
1,181 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0637 [0.0062, 0.1208] sex, age, birth date, deprivation index, 16 PCs
PPM011212 PGS002043
(portability-ldpred2_365)
PSS008188|
South Asian Ancestry|
6,176 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0216 [-0.0034, 0.0465] sex, age, birth date, deprivation index, 16 PCs
PPM011213 PGS002043
(portability-ldpred2_365)
PSS007971|
East Asian Ancestry|
1,783 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0214 [-0.0253, 0.068] sex, age, birth date, deprivation index, 16 PCs
PPM011214 PGS002043
(portability-ldpred2_365)
PSS007753|
African Ancestry|
2,447 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0126 [-0.0272, 0.0524] sex, age, birth date, deprivation index, 16 PCs
PPM011215 PGS002043
(portability-ldpred2_365)
PSS008858|
African Ancestry|
3,854 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0279 [-0.0037, 0.0595] sex, age, birth date, deprivation index, 16 PCs
PPM011210 PGS002043
(portability-ldpred2_365)
PSS008634|
European Ancestry|
6,540 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Glaucoma Partial Correlation (partial-r): 0.0366 [0.0123, 0.0608] sex, age, birth date, deprivation index, 16 PCs
PPM011216 PGS002044
(portability-ldpred2_366)
PSS009307|
European Ancestry|
20,000 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0497 [0.0359, 0.0635] sex, age, birth date, deprivation index, 16 PCs
PPM011217 PGS002044
(portability-ldpred2_366)
PSS009081|
European Ancestry|
4,136 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0835 [0.0531, 0.1137] sex, age, birth date, deprivation index, 16 PCs
PPM011218 PGS002044
(portability-ldpred2_366)
PSS008635|
European Ancestry|
6,660 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0633 [0.0393, 0.0873] sex, age, birth date, deprivation index, 16 PCs
PPM011219 PGS002044
(portability-ldpred2_366)
PSS008409|
Greater Middle Eastern Ancestry|
1,200 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.011 [-0.0461, 0.068] sex, age, birth date, deprivation index, 16 PCs
PPM011220 PGS002044
(portability-ldpred2_366)
PSS008189|
South Asian Ancestry|
6,331 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.09 [0.0654, 0.1144] sex, age, birth date, deprivation index, 16 PCs
PPM011222 PGS002044
(portability-ldpred2_366)
PSS007754|
African Ancestry|
2,484 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): -0.0166 [-0.0561, 0.0229] sex, age, birth date, deprivation index, 16 PCs
PPM011223 PGS002044
(portability-ldpred2_366)
PSS008859|
African Ancestry|
3,924 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): 0.0213 [-0.0101, 0.0526] sex, age, birth date, deprivation index, 16 PCs
PPM011221 PGS002044
(portability-ldpred2_366)
PSS007972|
East Asian Ancestry|
1,810 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Cataract Partial Correlation (partial-r): -0.0104 [-0.0567, 0.0359] sex, age, birth date, deprivation index, 16 PCs
PPM011225 PGS002045
(portability-ldpred2_371)
PSS009082|
European Ancestry|
4,069 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye Partial Correlation (partial-r): -0.007 [-0.0378, 0.0238] sex, age, birth date, deprivation index, 16 PCs
PPM011227 PGS002045
(portability-ldpred2_371)
PSS008410|
Greater Middle Eastern Ancestry|
1,183 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye Partial Correlation (partial-r): 0.0226 [-0.0349, 0.08] sex, age, birth date, deprivation index, 16 PCs
PPM011228 PGS002045
(portability-ldpred2_371)
PSS008190|
South Asian Ancestry|
6,184 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye Partial Correlation (partial-r): 0.01 [-0.015, 0.0349] sex, age, birth date, deprivation index, 16 PCs
PPM011229 PGS002045
(portability-ldpred2_371)
PSS007973|
East Asian Ancestry|
1,779 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye Partial Correlation (partial-r): -0.0042 [-0.0509, 0.0426] sex, age, birth date, deprivation index, 16 PCs
PPM011230 PGS002045
(portability-ldpred2_371)
PSS007755|
African Ancestry|
2,428 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye Partial Correlation (partial-r): -0.0067 [-0.0466, 0.0333] sex, age, birth date, deprivation index, 16 PCs
PPM011231 PGS002045
(portability-ldpred2_371)
PSS008860|
African Ancestry|
3,820 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye Partial Correlation (partial-r): -0.008 [-0.0397, 0.0238] sex, age, birth date, deprivation index, 16 PCs
PPM011224 PGS002045
(portability-ldpred2_371)
PSS009308|
European Ancestry|
19,618 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye Partial Correlation (partial-r): 0.0162 [0.0022, 0.0302] sex, age, birth date, deprivation index, 16 PCs
PPM011226 PGS002045
(portability-ldpred2_371)
PSS008636|
European Ancestry|
6,561 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye Partial Correlation (partial-r): 0.0309 [0.0067, 0.0551] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS004677
[
  • 561 cases
  • , 5,936 controls
]
African unspecified UKB
PSS004678
[
  • 115 cases
  • , 1,589 controls
]
East Asian UKB
PSS004679
[
  • 1,448 cases
  • , 23,457 controls
]
European non-white British ancestry UKB
PSS004680
[
  • 986 cases
  • , 6,845 controls
]
South Asian UKB
PSS004681
[
  • 4,189 cases
  • , 63,236 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004682
[
  • 57 cases
  • , 6,440 controls
]
African unspecified UKB
PSS004683
[
  • 12 cases
  • , 1,692 controls
]
East Asian UKB
PSS004684
[
  • 296 cases
  • , 24,609 controls
]
European non-white British ancestry UKB
PSS004685
[
  • 76 cases
  • , 7,755 controls
]
South Asian UKB
PSS004686
[
  • 908 cases
  • , 66,517 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004687
[
  • 125 cases
  • , 6,372 controls
]
African unspecified UKB
PSS004688
[
  • 43 cases
  • , 1,661 controls
]
East Asian UKB
PSS004689
[
  • 490 cases
  • , 24,415 controls
]
European non-white British ancestry UKB
PSS004690
[
  • 284 cases
  • , 7,547 controls
]
South Asian UKB
PSS004691
[
  • 1,549 cases
  • , 65,876 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004692
[
  • 129 cases
  • , 6,368 controls
]
African unspecified UKB
PSS004693
[
  • 9 cases
  • , 1,695 controls
]
East Asian UKB
PSS004694
[
  • 121 cases
  • , 24,784 controls
]
European non-white British ancestry UKB
PSS004695
[
  • 204 cases
  • , 7,627 controls
]
South Asian UKB
PSS004696
[
  • 363 cases
  • , 67,062 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004697
[
  • 307 cases
  • , 6,190 controls
]
African unspecified UKB
PSS004698
[
  • 34 cases
  • , 1,670 controls
]
East Asian UKB
PSS004699
[
  • 637 cases
  • , 24,268 controls
]
European non-white British ancestry UKB
PSS004700
[
  • 261 cases
  • , 7,570 controls
]
South Asian UKB
PSS004701
[
  • 1,890 cases
  • , 65,535 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS008171 6,081 individuals South Asian India (South Asia) UKB
PSS008185 6,095 individuals South Asian India (South Asia) UKB
PSS008186 6,037 individuals South Asian India (South Asia) UKB
PSS008187 6,052 individuals South Asian India (South Asia) UKB
PSS008188 6,176 individuals South Asian India (South Asia) UKB
PSS008189 6,331 individuals South Asian India (South Asia) UKB
PSS008190 6,184 individuals South Asian India (South Asia) UKB
PSS007739 2,385 individuals African American or Afro-Caribbean Carribean UKB
PSS003765
[
  • 182 cases
  • , 3,125 controls
]
African unspecified UKB
PSS003766
[
  • 14 cases
  • , 692 controls
]
East Asian UKB
PSS003767
[
  • 187 cases
  • , 9,532 controls
]
European non-white British ancestry UKB
PSS003768
[
  • 269 cases
  • , 3,264 controls
]
South Asian UKB
PSS003769
[
  • 444 cases
  • , 21,609 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007751 2,384 individuals African American or Afro-Caribbean Carribean UKB
PSS007752 2,374 individuals African American or Afro-Caribbean Carribean UKB
PSS009289 19,330 individuals European UK (+ Ireland) UKB
PSS007753 2,447 individuals African American or Afro-Caribbean Carribean UKB
PSS007754 2,484 individuals African American or Afro-Caribbean Carribean UKB
PSS007755 2,428 individuals African American or Afro-Caribbean Carribean UKB
PSS009303 19,445 individuals European UK (+ Ireland) UKB
PSS009304 19,413 individuals European UK (+ Ireland) UKB
PSS009305 19,321 individuals European UK (+ Ireland) UKB
PSS009306 19,592 individuals European UK (+ Ireland) UKB
PSS009307 20,000 individuals European UK (+ Ireland) UKB
PSS009308 19,618 individuals European UK (+ Ireland) UKB
PSS008842 3,732 individuals African unspecified Nigeria (West Africa) UKB
PSS000489 The diagnosttic criteria for each disease was based on gold-standard clinical guidelines. 339 individuals European
(Spanish)
PRECISESADS
PSS003849
[
  • 217 cases
  • , 3,124 controls
]
African unspecified UKB
PSS003850
[
  • 23 cases
  • , 692 controls
]
East Asian UKB
PSS003851
[
  • 373 cases
  • , 9,515 controls
]
European non-white British ancestry UKB
PSS003852
[
  • 178 cases
  • , 3,263 controls
]
South Asian UKB
PSS003853
[
  • 1,054 cases
  • , 21,569 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS008855 3,743 individuals African unspecified Nigeria (West Africa) UKB
PSS008856 3,723 individuals African unspecified Nigeria (West Africa) UKB
PSS008857 3,718 individuals African unspecified Nigeria (West Africa) UKB
PSS008858 3,854 individuals African unspecified Nigeria (West Africa) UKB
PSS008859 3,924 individuals African unspecified Nigeria (West Africa) UKB
PSS008860 3,820 individuals African unspecified Nigeria (West Africa) UKB
PSS004379
[
  • 637 cases
  • , 5,860 controls
]
African unspecified UKB
PSS004380
[
  • 140 cases
  • , 1,564 controls
]
East Asian UKB
PSS004381
[
  • 1,738 cases
  • , 23,167 controls
]
European non-white British ancestry UKB
PSS004382
[
  • 1,165 cases
  • , 6,666 controls
]
South Asian UKB
PSS004383
[
  • 5,153 cases
  • , 62,272 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS000245
[
  • 74 cases
  • , 1,721 controls
]
,
43.0 % Male samples
Mean = 64.02 years
Sd = 8.24 years
European BMES
PSS000246 MYOC p.Gln368Ter (rs74315329) carriers using imputation. Glaucoma cases were defined as those who (i) had an ICD-10 diagnosis of ‘primary open angle glaucoma’, ‘other glaucoma’ or ‘glaucoma, unspecified’; (ii) responded ‘glaucoma’ to the question ‘Has a doctor told you that you have any of the following problems with your eyes?’; or (iii) responded ‘glaucoma’ to the question ‘In the touch screen you selected that you have been told by a doctor that you have other serious illnesses or disabilities, could you now tell me what they are? (non-cancer illness).
[
  • 72 cases
  • , 893 controls
]
European UKB
PSS000247 ICD-10 defined Primary open-angle glaucoma (POAG)
[
  • 112 cases
  • , 3,000 controls
]
European UKB
PSS000248 Glaucoma cases were defined as those who (i) had an ICD-10 diagnosis of ‘primary open angle glaucoma’, ‘other glaucoma’ or ‘glaucoma, unspecified’; (ii) responded ‘glaucoma’ to the question ‘Has a doctor told you that you have any of the following problems with your eyes?’; or (iii) responded ‘glaucoma’ to the question ‘In the touch screen you selected that you have been told by a doctor that you have other serious illnesses or disabilities, could you now tell me what they are? (non-cancer illness).
[
  • 112 cases
  • , 3,000 controls
]
European UKB
PSS000249 Glaucoma cases were defined as those who (i) had an ICD-10 diagnosis of ‘primary open angle glaucoma’, ‘other glaucoma’ or ‘glaucoma, unspecified’; (ii) responded ‘glaucoma’ to the question ‘Has a doctor told you that you have any of the following problems with your eyes?’; or (iii) responded ‘glaucoma’ to the question ‘In the touch screen you selected that you have been told by a doctor that you have other serious illnesses or disabilities, could you now tell me what they are? (non-cancer illness).
[
  • 192 cases
  • , 6,841 controls
]
South Asian UKB
PSS004399
[
  • 3 cases
  • , 6,494 controls
]
African unspecified UKB
PSS004400
[
  • 14 cases
  • , 24,891 controls
]
European non-white British ancestry UKB
PSS004401
[
  • 4 cases
  • , 7,827 controls
]
South Asian UKB
PSS004402
[
  • 40 cases
  • , 67,385 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004408
[
  • 265 cases
  • , 6,232 controls
]
African unspecified UKB
PSS004409
[
  • 28 cases
  • , 1,676 controls
]
East Asian UKB
PSS004410
[
  • 477 cases
  • , 24,428 controls
]
European non-white British ancestry UKB
PSS004411
[
  • 218 cases
  • , 7,613 controls
]
South Asian UKB
PSS004412
[
  • 1,327 cases
  • , 66,098 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS000556 PheCode:190; ICD9CM:190.0, 190.1, 190.2, 190.3, 190.4, 190.5, 190.6, 190.7, 190.8, 190.9, 234.0, V10.84; ICD10CM:C69, C69.0, C69.00, C69.01, C69.02, C69.1, C69.10, C69.11, C69.12, C69.2, C69.20, C69.21, C69.22, C69.3, C69.30, C69.31, C69.32, C69.4, C69.40, C69.41, C69.42, C69.5, C69.50, C69.51, C69.52, C69.6, C69.60, C69.61, C69.62, C69.8, C69.80, C69.81, C69.82, C69.9, C69.90, C69.91, C69.92, D09.2, D09.20, D09.21, D09.22
[
  • 62 cases
  • , 610 controls
]
European MGI
PSS008393 1,162 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS004418
[
  • 47 cases
  • , 6,450 controls
]
African unspecified UKB
PSS004419
[
  • 11 cases
  • , 1,693 controls
]
East Asian UKB
PSS004420
[
  • 245 cases
  • , 24,660 controls
]
European non-white British ancestry UKB
PSS004421
[
  • 64 cases
  • , 7,767 controls
]
South Asian UKB
PSS004422
[
  • 772 cases
  • , 66,653 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS008405 1,169 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008406 1,165 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008407 1,162 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008408 1,181 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008409 1,200 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008410 1,183 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS004437
[
  • 17 cases
  • , 6,480 controls
]
African unspecified UKB
PSS004438
[
  • 4 cases
  • , 1,700 controls
]
East Asian UKB
PSS004439
[
  • 58 cases
  • , 24,847 controls
]
European non-white British ancestry UKB
PSS004440
[
  • 29 cases
  • , 7,802 controls
]
South Asian UKB
PSS004441
[
  • 135 cases
  • , 67,290 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS000512 A harmonized definition of POAG used the following criteria: (1) open anterior segment angles; (2) reproducible glaucomatous visual field loss on reliable tests; or (3) an eye with cup-disc ratio of at least 0.7 with 1 visual field showing glaucomatous loss; and (4) no identifiable secondary cause for optic nerve disease. 
[
  • 3,108 cases
  • , 3,430 controls
]
,
43.38 % Male samples
European GLAUGEN, NEIGHBOR
PSS000513 A harmonized definition of POAG used the following criteria: (1) open anterior segment angles; (2) reproducible glaucomatous visual field loss on reliable tests; or (3) an eye with cup-disc ratio of at least 0.7 with 1 visual field showing glaucomatous loss; and (4) no identifiable secondary cause for optic nerve disease. 
[
  • 2,947 cases
  • , 0 controls
]
European GLAUGEN, NEIGHBOR
PSS003974
[
  • 68 cases
  • , 3,128 controls
]
African unspecified UKB
PSS003975
[
  • 18 cases
  • , 693 controls
]
East Asian UKB
PSS003976
[
  • 235 cases
  • , 9,520 controls
]
European non-white British ancestry UKB
PSS003977
[
  • 63 cases
  • , 3,264 controls
]
South Asian UKB
PSS003978
[
  • 637 cases
  • , 21,571 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007958 1,764 individuals East Asian China (East Asia) UKB
PSS007969 1,773 individuals East Asian China (East Asia) UKB
PSS007970 1,775 individuals East Asian China (East Asia) UKB
PSS007971 1,783 individuals East Asian China (East Asia) UKB
PSS007972 1,810 individuals East Asian China (East Asia) UKB
PSS007973 1,779 individuals East Asian China (East Asia) UKB
PSS001065 All individuals had type 2 diabetes (T2D). Cases were individuals with diabetic retinopathy (DR). T2D was ascertained with ICD-10 from E11.0-E11.9. DR was ascertained with an ICD-10 of E11.3.
[
  • 317 cases
  • , 1,608 controls
]
African American or Afro-Caribbean Mount Sinai
PSS001066 All individuals had type 2 diabetes (T2D). Cases were individuals with diabetic retinopathy (DR). T2D was ascertained with ICD-10 from E11.0-E11.9. DR was ascertained with an ICD-10 of E11.3.
[
  • 90 cases
  • , 888 controls
]
European Mount Sinai
PSS001067 All individuals had type 2 diabetes (T2D). Cases were individuals with diabetic retinopathy (DR). T2D was ascertained with ICD-10 from E11.0-E11.9. DR was ascertained with an ICD-10 of E11.3.
[
  • 90 cases
  • , 888 controls
]
European Mount Sinai
PSS001067 All individuals had type 2 diabetes (T2D). Cases were individuals with diabetic retinopathy (DR). T2D was ascertained with ICD-10 from E11.0-E11.9. DR was ascertained with an ICD-10 of E11.3.
[
  • 317 cases
  • , 1,608 controls
]
African American or Afro-Caribbean Mount Sinai
PSS001067 All individuals had type 2 diabetes (T2D). Cases were individuals with diabetic retinopathy (DR). T2D was ascertained with ICD-10 from E11.0-E11.9. DR was ascertained with an ICD-10 of E11.3.
[
  • 507 cases
  • , 2,182 controls
]
Hispanic or Latin American Mount Sinai
PSS001067 All individuals had type 2 diabetes (T2D). Cases were individuals with diabetic retinopathy (DR). T2D was ascertained with ICD-10 from E11.0-E11.9. DR was ascertained with an ICD-10 of E11.3.
[
  • 49 cases
  • , 438 controls
]
Asian unspecified, Native American, NR Mount Sinai
PSS009063 4,032 individuals European Poland (NE Europe) UKB
PSS009077 4,055 individuals European Poland (NE Europe) UKB
PSS009078 4,043 individuals European Poland (NE Europe) UKB
PSS009079 4,029 individuals European Poland (NE Europe) UKB
PSS009080 4,066 individuals European Poland (NE Europe) UKB
PSS009081 4,136 individuals European Poland (NE Europe) UKB
PSS009082 4,069 individuals European Poland (NE Europe) UKB
PSS001084 Moderate Age-Related Diabetes (MARD) vs. controls
[
  • 2,853 cases
  • , 2,744 controls
]
European Swedish ANDIS
PSS001085 Moderate Obesity-related Diabetes (MOD) vs. controls
[
  • 1,372 cases
  • , 2,744 controls
]
European Swedish ANDIS
PSS001086 Severe Autoimmune Diabetes (SAID) vs. controls
[
  • 450 cases
  • , 2,744 controls
]
European Swedish ANDIS
PSS001087 Severe Insulin-Deficient Diabetes (SIDD) vs. controls
[
  • 1,186 cases
  • , 2,744 controls
]
European Swedish ANDIS
PSS001088 Severe Insulin-Resistant Diabetes (SIRD) vs. controls
[
  • 1,125 cases
  • , 2,744 controls
]
European Swedish ANDIS
PSS000977 Cases, classified by fellowship-trained glaucoma specialists were defined as having an open iridocorneal angle and characteristic optic nerve defects with corresponding visual field loss, whereas controls, classified by fellowship-trained glaucoma specialists exhibited a lack of confounding ocular conditions.
[
  • 1,783 cases
  • , 2,047 controls
]
,
36.4 % Male samples
African American or Afro-Caribbean, African unspecified POAAGG
PSS000978 Cases, classified by fellowship-trained glaucoma specialists were defined as having an open iridocorneal angle and characteristic optic nerve defects with corresponding visual field loss, whereas controls, classified by fellowship-trained glaucoma specialists exhibited a lack of confounding ocular conditions.
[
  • 755 cases
  • , 1,380 controls
]
African American or Afro-Caribbean, African unspecified POAAGG
PSS008617 6,465 individuals European Italy (South Europe) UKB
PSS008631 6,514 individuals European Italy (South Europe) UKB
PSS008632 6,470 individuals European Italy (South Europe) UKB
PSS008633 6,462 individuals European Italy (South Europe) UKB
PSS008634 6,540 individuals European Italy (South Europe) UKB
PSS008635 6,660 individuals European Italy (South Europe) UKB
PSS008636 6,561 individuals European Italy (South Europe) UKB
PSS004662
[
  • 34 cases
  • , 6,463 controls
]
African unspecified UKB
PSS004663
[
  • 3 cases
  • , 1,701 controls
]
East Asian UKB
PSS004664
[
  • 104 cases
  • , 24,801 controls
]
European non-white British ancestry UKB
PSS004665
[
  • 61 cases
  • , 7,770 controls
]
South Asian UKB
PSS004666
[
  • 353 cases
  • , 67,072 controls
]
European white British ancestry UKB Testing cohort (heldout set)