Trait: wellbeing measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007869
Description quantification of some aspect of wellbeing such as life satisfaction or emotional wellbeing, usually self-reported and quantified through the use of a structured questionnaire
Trait category
Other measurement
Mapped term PMID:27089181
Child trait(s) 2 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "wellbeing measurement" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001008
(GBE_QT_FC1002178)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Overall health rating health satisfaction measurement 10,464
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001008/ScoringFiles/PGS001008.txt.gz
PGS001090
(GBE_BIN_FC40020489)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Often felt loved as a child wellbeing measurement 7,555
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001090/ScoringFiles/PGS001090.txt.gz
PGS001398
(GBE_QT_FC1004570)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Friendship satisfaction friendship satisfaction measurement 659
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001398/ScoringFiles/PGS001398.txt.gz
PGS001401
(GBE_QT_FC1004548)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Health satisfaction health satisfaction measurement 1,814
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001401/ScoringFiles/PGS001401.txt.gz
PGS001935
(portability-PLR_less_happy_with_health)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 General happiness with own health health satisfaction measurement 9,070
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001935/ScoringFiles/PGS001935.txt.gz
PGS001936
(portability-PLR_less_happy)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 General happiness wellbeing measurement 10,628
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001936/ScoringFiles/PGS001936.txt.gz
PGS002153
(portability-ldpred2_less_happy_with_health)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 General happiness with own health health satisfaction measurement 824,602
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002153/ScoringFiles/PGS002153.txt.gz
PGS002154
(portability-ldpred2_less_happy)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 General happiness wellbeing measurement 806,011
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002154/ScoringFiles/PGS002154.txt.gz
PGS003518
(cont-decay-less_happy)
 PGP000457 |
Ding Y et al. Nature (2023)
 General happiness wellbeing measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003518/ScoringFiles/PGS003518.txt.gz
PGS003519
(cont-decay-less_happy_with_health)
 PGP000457 |
Ding Y et al. Nature (2023)
 General happiness with own health health satisfaction measurement 979,739
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003519/ScoringFiles/PGS003519.txt.gz
PGS004503
(disease.Z72.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Z72 (Problems related to lifestyle) wellbeing measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004503/ScoringFiles/PGS004503.txt.gz
PGS004573
(meta.Z72.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Z72 (Problems related to lifestyle) wellbeing measurement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004573/ScoringFiles/PGS004573.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007803 PGS001008
(GBE_QT_FC1002178)
 PSS007591|
African Ancestry|
6,303 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.02094 [0.01405, 0.02782]
Incremental R2 (full-covars): -0.00287
PGS R2 (no covariates): 0.00121 [-0.00048, 0.0029]		 age, sex, UKB array type, Genotype PCs —
PPM007804 PGS001008
(GBE_QT_FC1002178)
 PSS007592|
East Asian Ancestry|
1,636 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.01726 [0.00503, 0.0295]
Incremental R2 (full-covars): -0.00444
PGS R2 (no covariates): 0.00157 [-0.00218, 0.00533]		 age, sex, UKB array type, Genotype PCs —
PPM007805 PGS001008
(GBE_QT_FC1002178)
 PSS007593|
European Ancestry|
24,733 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.03896 [0.03425, 0.04368]
Incremental R2 (full-covars): 0.01798
PGS R2 (no covariates): 0.02029 [0.01682, 0.02375]		 age, sex, UKB array type, Genotype PCs —
PPM007806 PGS001008
(GBE_QT_FC1002178)
 PSS007594|
South Asian Ancestry|
7,568 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.02097 [0.01469, 0.02725]
Incremental R2 (full-covars): 0.00755
PGS R2 (no covariates): 0.00811 [0.00415, 0.01206]		 age, sex, UKB array type, Genotype PCs —
PPM007807 PGS001008
(GBE_QT_FC1002178)
 PSS007595|
European Ancestry|
67,195 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Overall health rating — — R²: 0.02852 [0.02605, 0.031]
Incremental R2 (full-covars): 0.01945
PGS R2 (no covariates): 0.02062 [0.0185, 0.02274]		 age, sex, UKB array type, Genotype PCs —
PPM008193 PGS001090
(GBE_BIN_FC40020489)
 PSS003939|
African Ancestry|
695 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Often felt loved as a child — AUROC: 0.61181 [0.56997, 0.65365] R²: 0.0544
Incremental AUROC (full-covars): -0.02903
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.5072 [0.46391, 0.55048]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008194 PGS001090
(GBE_BIN_FC40020489)
 PSS003940|
East Asian Ancestry|
264 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Often felt loved as a child — AUROC: 0.65378 [0.5874, 0.72015] R²: 0.08841
Incremental AUROC (full-covars): -0.03538
PGS R2 (no covariates): 0.0101
PGS AUROC (no covariates): 0.46612 [0.39605, 0.53618]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008195 PGS001090
(GBE_BIN_FC40020489)
 PSS003941|
European Ancestry|
6,160 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Often felt loved as a child — AUROC: 0.55842 [0.54349, 0.57335] R²: 0.01334
Incremental AUROC (full-covars): 0.0304
PGS R2 (no covariates): 0.01114
PGS AUROC (no covariates): 0.55257 [0.53762, 0.56751]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008196 PGS001090
(GBE_BIN_FC40020489)
 PSS003942|
South Asian Ancestry|
790 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Often felt loved as a child — AUROC: 0.56556 [0.5235, 0.60762] R²: 0.01512
Incremental AUROC (full-covars): -0.02764
PGS R2 (no covariates): 0.00069
PGS AUROC (no covariates): 0.51244 [0.47037, 0.5545]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008197 PGS001090
(GBE_BIN_FC40020489)
 PSS003943|
European Ancestry|
16,485 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Often felt loved as a child — AUROC: 0.54953 [0.53996, 0.5591] R²: 0.0088
Incremental AUROC (full-covars): 0.03491
PGS R2 (no covariates): 0.00777
PGS AUROC (no covariates): 0.54645 [0.53688, 0.55602]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007255 PGS001398
(GBE_QT_FC1004570)
 PSS007606|
African Ancestry|
3,707 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Friendships satisfaction — — R²: 0.00439 [0.00119, 0.0076]
Incremental R2 (full-covars): -0.00158
PGS R2 (no covariates): 0.00016 [-0.00046, 0.00079]		 age, sex, UKB array type, Genotype PCs —
PPM007256 PGS001398
(GBE_QT_FC1004570)
 PSS007607|
East Asian Ancestry|
782 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Friendships satisfaction — — R²: 0.01093 [0.00113, 0.02073]
Incremental R2 (full-covars): -0.00284
PGS R2 (no covariates): 0.00036 [-0.00143, 0.00214]		 age, sex, UKB array type, Genotype PCs —
PPM007257 PGS001398
(GBE_QT_FC1004570)
 PSS007608|
European Ancestry|
10,751 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Friendships satisfaction — — R²: 0.01912 [0.01575, 0.02249]
Incremental R2 (full-covars): -0.00089
PGS R2 (no covariates): 0.00011 [-0.00015, 0.00038]		 age, sex, UKB array type, Genotype PCs —
PPM007258 PGS001398
(GBE_QT_FC1004570)
 PSS007609|
South Asian Ancestry|
4,922 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Friendships satisfaction — — R²: 0.00983 [0.00548, 0.01418]
Incremental R2 (full-covars): -0.00092
PGS R2 (no covariates): 9e-05 [-0.00033, 0.00052]		 age, sex, UKB array type, Genotype PCs —
PPM007259 PGS001398
(GBE_QT_FC1004570)
 PSS007610|
European Ancestry|
26,257 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Friendships satisfaction — — R²: 0.01886 [0.01682, 0.02089]
Incremental R2 (full-covars): 0.00139
PGS R2 (no covariates): 0.00143 [0.00086, 0.002]		 age, sex, UKB array type, Genotype PCs —
PPM007250 PGS001401
(GBE_QT_FC1004548)
 PSS007601|
African Ancestry|
3,770 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.01436 [0.00862, 0.0201]
Incremental R2 (full-covars): -0.00107
PGS R2 (no covariates): 0.00031 [-0.00055, 0.00117]		 age, sex, UKB array type, Genotype PCs —
PPM007251 PGS001401
(GBE_QT_FC1004548)
 PSS007602|
East Asian Ancestry|
773 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.01047 [0.00087, 0.02006]
Incremental R2 (full-covars): -0.00364
PGS R2 (no covariates): 0.0 [-0.0002, 0.00021]		 age, sex, UKB array type, Genotype PCs —
PPM007252 PGS001401
(GBE_QT_FC1004548)
 PSS007603|
European Ancestry|
10,834 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.01053 [0.00801, 0.01305]
Incremental R2 (full-covars): 0.00325
PGS R2 (no covariates): 0.00366 [0.00217, 0.00516]		 age, sex, UKB array type, Genotype PCs —
PPM007253 PGS001401
(GBE_QT_FC1004548)
 PSS007604|
South Asian Ancestry|
4,984 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.01007 [0.00567, 0.01447]
Incremental R2 (full-covars): -0.00147
PGS R2 (no covariates): 0.00014 [-0.00038, 0.00065]		 age, sex, UKB array type, Genotype PCs —
PPM007254 PGS001401
(GBE_QT_FC1004548)
 PSS007605|
European Ancestry|
26,439 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Health satisfaction — — R²: 0.00501 [0.00394, 0.00607]
Incremental R2 (full-covars): 0.00135
PGS R2 (no covariates): 0.00204 [0.00136, 0.00272]		 age, sex, UKB array type, Genotype PCs —
PPM010356 PGS001935
(portability-PLR_less_happy_with_health)
 PSS009197|
European Ancestry|
1,246 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0746 [0.0187, 0.1301] sex, age, birth date, deprivation index, 16 PCs —
PPM010357 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008751|
European Ancestry|
2,257 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0562 [0.0148, 0.0975] sex, age, birth date, deprivation index, 16 PCs —
PPM010358 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008525|
Greater Middle Eastern Ancestry|
199 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): -0.0096 [-0.156, 0.1373] sex, age, birth date, deprivation index, 16 PCs —
PPM010359 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008303|
South Asian Ancestry|
815 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0029 [-0.0667, 0.0724] sex, age, birth date, deprivation index, 16 PCs —
PPM010360 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008080|
East Asian Ancestry|
423 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): -0.0063 [-0.1039, 0.0915] sex, age, birth date, deprivation index, 16 PCs —
PPM010361 PGS001935
(portability-PLR_less_happy_with_health)
 PSS007867|
African Ancestry|
374 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0167 [-0.0877, 0.1207] sex, age, birth date, deprivation index, 16 PCs —
PPM010362 PGS001935
(portability-PLR_less_happy_with_health)
 PSS008971|
African Ancestry|
511 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0279 [-0.0607, 0.1161] sex, age, birth date, deprivation index, 16 PCs —
PPM010355 PGS001935
(portability-PLR_less_happy_with_health)
 PSS009423|
European Ancestry|
6,445 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.064 [0.0396, 0.0883] sex, age, birth date, deprivation index, 16 PCs —
PPM010363 PGS001936
(portability-PLR_less_happy)
 PSS009422|
European Ancestry|
6,429 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0697 [0.0453, 0.094] sex, age, birth date, deprivation index, 16 PCs —
PPM010364 PGS001936
(portability-PLR_less_happy)
 PSS009196|
European Ancestry|
1,241 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0305 [-0.0257, 0.0864] sex, age, birth date, deprivation index, 16 PCs —
PPM010365 PGS001936
(portability-PLR_less_happy)
 PSS008750|
European Ancestry|
2,243 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0421 sex, age, birth date, deprivation index, 16 PCs —
PPM010366 PGS001936
(portability-PLR_less_happy)
 PSS008524|
Greater Middle Eastern Ancestry|
199 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): -0.1188 [-0.2609, 0.0284] sex, age, birth date, deprivation index, 16 PCs —
PPM010367 PGS001936
(portability-PLR_less_happy)
 PSS008302|
South Asian Ancestry|
809 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.005 [-0.0648, 0.0748] sex, age, birth date, deprivation index, 16 PCs —
PPM010368 PGS001936
(portability-PLR_less_happy)
 PSS008079|
East Asian Ancestry|
424 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0412 [-0.0566, 0.1382] sex, age, birth date, deprivation index, 16 PCs —
PPM010369 PGS001936
(portability-PLR_less_happy)
 PSS007866|
African Ancestry|
368 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): -0.0999 [-0.2029, 0.0053] sex, age, birth date, deprivation index, 16 PCs —
PPM010370 PGS001936
(portability-PLR_less_happy)
 PSS008970|
African Ancestry|
503 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0139 [-0.0754, 0.103] sex, age, birth date, deprivation index, 16 PCs —
PPM012075 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008303|
South Asian Ancestry|
815 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0875 [0.0181, 0.1561] sex, age, birth date, deprivation index, 16 PCs —
PPM012071 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS009423|
European Ancestry|
6,445 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.1032 [0.0789, 0.1273] sex, age, birth date, deprivation index, 16 PCs —
PPM012072 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS009197|
European Ancestry|
1,246 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.119 [0.0634, 0.1738] sex, age, birth date, deprivation index, 16 PCs —
PPM012073 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008751|
European Ancestry|
2,257 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0596 [0.0182, 0.1008] sex, age, birth date, deprivation index, 16 PCs —
PPM012074 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008525|
Greater Middle Eastern Ancestry|
199 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0755 [-0.072, 0.2197] sex, age, birth date, deprivation index, 16 PCs —
PPM012076 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008080|
East Asian Ancestry|
423 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0795 [-0.0183, 0.1759] sex, age, birth date, deprivation index, 16 PCs —
PPM012077 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS007867|
African Ancestry|
374 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): -0.046 [-0.1495, 0.0585] sex, age, birth date, deprivation index, 16 PCs —
PPM012078 PGS002153
(portability-ldpred2_less_happy_with_health)
 PSS008971|
African Ancestry|
511 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness with own health — — Partial Correlation (partial-r): 0.0167 [-0.0719, 0.105] sex, age, birth date, deprivation index, 16 PCs —
PPM012079 PGS002154
(portability-ldpred2_less_happy)
 PSS009422|
European Ancestry|
6,429 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.105 [0.0807, 0.1291] sex, age, birth date, deprivation index, 16 PCs —
PPM012080 PGS002154
(portability-ldpred2_less_happy)
 PSS009196|
European Ancestry|
1,241 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0947 [0.0389, 0.1501] sex, age, birth date, deprivation index, 16 PCs —
PPM012081 PGS002154
(portability-ldpred2_less_happy)
 PSS008750|
European Ancestry|
2,243 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0889 [0.0475, 0.1299] sex, age, birth date, deprivation index, 16 PCs —
PPM012082 PGS002154
(portability-ldpred2_less_happy)
 PSS008524|
Greater Middle Eastern Ancestry|
199 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0539 [-0.0935, 0.199] sex, age, birth date, deprivation index, 16 PCs —
PPM012083 PGS002154
(portability-ldpred2_less_happy)
 PSS008302|
South Asian Ancestry|
809 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0216 [-0.0483, 0.0912] sex, age, birth date, deprivation index, 16 PCs —
PPM012084 PGS002154
(portability-ldpred2_less_happy)
 PSS008079|
East Asian Ancestry|
424 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0257 [-0.0721, 0.1229] sex, age, birth date, deprivation index, 16 PCs —
PPM012085 PGS002154
(portability-ldpred2_less_happy)
 PSS007866|
African Ancestry|
368 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0163 [-0.0889, 0.1213] sex, age, birth date, deprivation index, 16 PCs —
PPM012086 PGS002154
(portability-ldpred2_less_happy)
 PSS008970|
African Ancestry|
503 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: General happiness — — Partial Correlation (partial-r): 0.0196 [-0.0697, 0.1086] sex, age, birth date, deprivation index, 16 PCs —
PPM017446 PGS003518
(cont-decay-less_happy)
 PSS010880|
European Ancestry|
6,472 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017530 PGS003518
(cont-decay-less_happy)
 PSS010796|
European Ancestry|
1,241 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017614 PGS003518
(cont-decay-less_happy)
 PSS010628|
European Ancestry|
2,169 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017698 PGS003518
(cont-decay-less_happy)
 PSS010544|
Greater Middle Eastern Ancestry|
199 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017782 PGS003518
(cont-decay-less_happy)
 PSS010208|
European Ancestry|
940 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017866 PGS003518
(cont-decay-less_happy)
 PSS010460|
South Asian Ancestry|
809 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017950 PGS003518
(cont-decay-less_happy)
 PSS010376|
East Asian Ancestry|
425 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM018034 PGS003518
(cont-decay-less_happy)
 PSS010292|
African Ancestry|
368 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM018118 PGS003518
(cont-decay-less_happy)
 PSS010712|
African Ancestry|
502 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017447 PGS003519
(cont-decay-less_happy_with_health)
 PSS010882|
European Ancestry|
6,496 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017531 PGS003519
(cont-decay-less_happy_with_health)
 PSS010798|
European Ancestry|
1,246 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017699 PGS003519
(cont-decay-less_happy_with_health)
 PSS010546|
Greater Middle Eastern Ancestry|
199 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness with own health — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017783 PGS003519
(cont-decay-less_happy_with_health)
 PSS010210|
European Ancestry|
948 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017867 PGS003519
(cont-decay-less_happy_with_health)
 PSS010462|
South Asian Ancestry|
815 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM017951 PGS003519
(cont-decay-less_happy_with_health)
 PSS010378|
East Asian Ancestry|
424 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness with own health — — partial-R2: 0.01 sex, age, deprivation index, PC1-16 —
PPM018035 PGS003519
(cont-decay-less_happy_with_health)
 PSS010294|
African Ancestry|
374 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness with own health — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM018119 PGS003519
(cont-decay-less_happy_with_health)
 PSS010714|
African Ancestry|
510 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness with own health — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM017615 PGS003519
(cont-decay-less_happy_with_health)
 PSS010630|
European Ancestry|
2,183 individuals
 PGP000457 |
Ding Y et al. Nature (2023)
 Reported Trait: General happiness with own health — — partial-R2: 0.0 sex, age, deprivation index, PC1-16 —
PPM020618 PGS004503
(disease.Z72.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Z72 (Problems related to lifestyle) OR: 1.15608 — — — —
PPM020688 PGS004573
(meta.Z72.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: Z72 (Problems related to lifestyle) OR: 1.21564 — — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008524 — — 199 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS008525 — — 199 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009422 — — 6,429 individuals — European UK (+ Ireland) UKB —
PSS009423 — — 6,445 individuals — European UK (+ Ireland) UKB —
PSS010796 — — 1,241 individuals,
34.0 % Male samples
 Mean = 54.0 years
Sd = 7.3 years		 European Polish UKB —
PSS010798 — — 1,246 individuals,
34.0 % Male samples
 Mean = 54.0 years
Sd = 7.2 years		 European Polish UKB —
PSS010544 — — 199 individuals,
56.0 % Male samples
 Mean = 53.8 years
Sd = 7.2 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010546 — — 199 individuals,
56.0 % Male samples
 Mean = 54.0 years
Sd = 7.3 years		 Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB —
PSS010292 — — 368 individuals,
32.0 % Male samples
 Mean = 50.5 years
Sd = 7.4 years		 African American or Afro-Caribbean Caribbean UKB —
PSS010294 — — 374 individuals,
31.0 % Male samples
 Mean = 50.4 years
Sd = 7.3 years		 African American or Afro-Caribbean Caribbean UKB —
PSS003939 — —
[
  • 376 cases
  • , 319 controls
]
 — African unspecified — UKB —
PSS003940 — —
[
  • 122 cases
  • , 142 controls
]
 — East Asian — UKB —
PSS003941 — —
[
  • 3,974 cases
  • , 2,186 controls
]
 — European non-white British ancestry UKB —
PSS003942 — —
[
  • 526 cases
  • , 264 controls
]
 — South Asian — UKB —
PSS003943 — —
[
  • 11,635 cases
  • , 4,850 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS009197 — — 1,246 individuals — European Poland (NE Europe) UKB —
PSS008303 — — 815 individuals — South Asian India (South Asia) UKB —
PSS009196 — — 1,241 individuals — European Poland (NE Europe) UKB —
PSS008302 — — 809 individuals — South Asian India (South Asia) UKB —
PSS010712 — — 502 individuals,
48.0 % Male samples
 Mean = 50.7 years
Sd = 7.2 years		 African unspecified Nigerian UKB —
PSS010714 — — 510 individuals,
48.0 % Male samples
 Mean = 50.6 years
Sd = 7.2 years		 African unspecified Nigerian UKB —
PSS010460 — — 809 individuals,
57.0 % Male samples
 Mean = 52.7 years
Sd = 8.2 years		 South Asian Indian UKB —
PSS010462 — — 815 individuals,
57.0 % Male samples
 Mean = 52.6 years
Sd = 8.2 years		 South Asian Indian UKB —
PSS010208 — — 940 individuals,
43.0 % Male samples
 Mean = 57.6 years
Sd = 7.0 years		 European Ashkenazi UKB —
PSS010210 — — 948 individuals,
43.0 % Male samples
 Mean = 57.6 years
Sd = 7.0 years		 European Ashkenazi UKB —
PSS008970 — — 503 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008971 — — 511 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008079 — — 424 individuals — East Asian China (East Asia) UKB —
PSS008080 — — 423 individuals — East Asian China (East Asia) UKB —
PSS011364 — — 56,192 individuals — European — UKB —
PSS010880 — — 6,472 individuals,
45.0 % Male samples
 Mean = 56.2 years
Sd = 7.7 years		 European white British UKB —
PSS010882 — — 6,496 individuals,
45.0 % Male samples
 Mean = 56.2 years
Sd = 7.6 years		 European white British UKB —
PSS010628 — — 2,169 individuals,
41.0 % Male samples
 Mean = 54.0 years
Sd = 8.1 years		 European Italian UKB —
PSS010630 — — 2,183 individuals,
41.0 % Male samples
 Mean = 53.9 years
Sd = 8.1 years		 European Italian UKB —
PSS008750 — — 2,243 individuals — European Italy (South Europe) UKB —
PSS007591 — — 6,303 individuals — African unspecified — UKB —
PSS007592 — — 1,636 individuals — East Asian — UKB —
PSS007593 — — 24,733 individuals — European non-white British ancestry UKB —
PSS007594 — — 7,568 individuals — South Asian — UKB —
PSS007595 — — 67,195 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS008751 — — 2,257 individuals — European Italy (South Europe) UKB —
PSS007867 — — 374 individuals — African American or Afro-Caribbean Carribean UKB —
PSS010376 — — 425 individuals,
27.0 % Male samples
 Mean = 52.4 years
Sd = 7.3 years		 East Asian Chinese UKB —
PSS010378 — — 424 individuals,
26.0 % Male samples
 Mean = 52.3 years
Sd = 7.3 years		 East Asian Chinese UKB —
PSS007601 — — 3,770 individuals — African unspecified — UKB —
PSS007602 — — 773 individuals — East Asian — UKB —
PSS007603 — — 10,834 individuals — European non-white British ancestry UKB —
PSS007604 — — 4,984 individuals — South Asian — UKB —
PSS007605 — — 26,439 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007606 — — 3,707 individuals — African unspecified — UKB —
PSS007607 — — 782 individuals — East Asian — UKB —
PSS007608 — — 10,751 individuals — European non-white British ancestry UKB —
PSS007609 — — 4,922 individuals — South Asian — UKB —
PSS007610 — — 26,257 individuals — European white British ancestry UKB Testing cohort (heldout set)
PSS007866 — — 368 individuals — African American or Afro-Caribbean Carribean UKB —