Trait: wellbeing measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007869
Description quantification of some aspect of wellbeing such as life satisfaction or emotional wellbeing, usually self-reported and quantified through the use of a structured questionnaire
Trait category
Other measurement
Mapped term PMID:27089181
Child trait(s) 2 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "wellbeing measurement" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001008
(GBE_QT_FC1002178)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Overall health rating health satisfaction measurement 10,464
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001008/ScoringFiles/PGS001008.txt.gz
PGS001090
(GBE_BIN_FC40020489)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Often felt loved as a child wellbeing measurement 7,555
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001090/ScoringFiles/PGS001090.txt.gz
PGS001398
(GBE_QT_FC1004570)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Friendship satisfaction friendship satisfaction measurement 659
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001398/ScoringFiles/PGS001398.txt.gz
PGS001401
(GBE_QT_FC1004548)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Health satisfaction health satisfaction measurement 1,814
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001401/ScoringFiles/PGS001401.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007803 PGS001008
(GBE_QT_FC1002178)
PSS007591|
African Ancestry|
6,303 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Overall health rating : 0.02094 [0.01405, 0.02782]
Incremental R2 (full-covars): -0.00287
PGS R2 (no covariates): 0.00121 [-0.00048, 0.0029]
age, sex, UKB array type, Genotype PCs
PPM007804 PGS001008
(GBE_QT_FC1002178)
PSS007592|
East Asian Ancestry|
1,636 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Overall health rating : 0.01726 [0.00503, 0.0295]
Incremental R2 (full-covars): -0.00444
PGS R2 (no covariates): 0.00157 [-0.00218, 0.00533]
age, sex, UKB array type, Genotype PCs
PPM007805 PGS001008
(GBE_QT_FC1002178)
PSS007593|
European Ancestry|
24,733 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Overall health rating : 0.03896 [0.03425, 0.04368]
Incremental R2 (full-covars): 0.01798
PGS R2 (no covariates): 0.02029 [0.01682, 0.02375]
age, sex, UKB array type, Genotype PCs
PPM007806 PGS001008
(GBE_QT_FC1002178)
PSS007594|
South Asian Ancestry|
7,568 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Overall health rating : 0.02097 [0.01469, 0.02725]
Incremental R2 (full-covars): 0.00755
PGS R2 (no covariates): 0.00811 [0.00415, 0.01206]
age, sex, UKB array type, Genotype PCs
PPM007807 PGS001008
(GBE_QT_FC1002178)
PSS007595|
European Ancestry|
67,195 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Overall health rating : 0.02852 [0.02605, 0.031]
Incremental R2 (full-covars): 0.01945
PGS R2 (no covariates): 0.02062 [0.0185, 0.02274]
age, sex, UKB array type, Genotype PCs
PPM008193 PGS001090
(GBE_BIN_FC40020489)
PSS003939|
African Ancestry|
695 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Often felt loved as a child AUROC: 0.61181 [0.56997, 0.65365] : 0.0544
Incremental AUROC (full-covars): -0.02903
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.5072 [0.46391, 0.55048]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008194 PGS001090
(GBE_BIN_FC40020489)
PSS003940|
East Asian Ancestry|
264 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Often felt loved as a child AUROC: 0.65378 [0.5874, 0.72015] : 0.08841
Incremental AUROC (full-covars): -0.03538
PGS R2 (no covariates): 0.0101
PGS AUROC (no covariates): 0.46612 [0.39605, 0.53618]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008195 PGS001090
(GBE_BIN_FC40020489)
PSS003941|
European Ancestry|
6,160 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Often felt loved as a child AUROC: 0.55842 [0.54349, 0.57335] : 0.01334
Incremental AUROC (full-covars): 0.0304
PGS R2 (no covariates): 0.01114
PGS AUROC (no covariates): 0.55257 [0.53762, 0.56751]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008196 PGS001090
(GBE_BIN_FC40020489)
PSS003942|
South Asian Ancestry|
790 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Often felt loved as a child AUROC: 0.56556 [0.5235, 0.60762] : 0.01512
Incremental AUROC (full-covars): -0.02764
PGS R2 (no covariates): 0.00069
PGS AUROC (no covariates): 0.51244 [0.47037, 0.5545]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008197 PGS001090
(GBE_BIN_FC40020489)
PSS003943|
European Ancestry|
16,485 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Often felt loved as a child AUROC: 0.54953 [0.53996, 0.5591] : 0.0088
Incremental AUROC (full-covars): 0.03491
PGS R2 (no covariates): 0.00777
PGS AUROC (no covariates): 0.54645 [0.53688, 0.55602]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007255 PGS001398
(GBE_QT_FC1004570)
PSS007606|
African Ancestry|
3,707 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Friendships satisfaction : 0.00439 [0.00119, 0.0076]
Incremental R2 (full-covars): -0.00158
PGS R2 (no covariates): 0.00016 [-0.00046, 0.00079]
age, sex, UKB array type, Genotype PCs
PPM007256 PGS001398
(GBE_QT_FC1004570)
PSS007607|
East Asian Ancestry|
782 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Friendships satisfaction : 0.01093 [0.00113, 0.02073]
Incremental R2 (full-covars): -0.00284
PGS R2 (no covariates): 0.00036 [-0.00143, 0.00214]
age, sex, UKB array type, Genotype PCs
PPM007257 PGS001398
(GBE_QT_FC1004570)
PSS007608|
European Ancestry|
10,751 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Friendships satisfaction : 0.01912 [0.01575, 0.02249]
Incremental R2 (full-covars): -0.00089
PGS R2 (no covariates): 0.00011 [-0.00015, 0.00038]
age, sex, UKB array type, Genotype PCs
PPM007258 PGS001398
(GBE_QT_FC1004570)
PSS007609|
South Asian Ancestry|
4,922 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Friendships satisfaction : 0.00983 [0.00548, 0.01418]
Incremental R2 (full-covars): -0.00092
PGS R2 (no covariates): 9e-05 [-0.00033, 0.00052]
age, sex, UKB array type, Genotype PCs
PPM007259 PGS001398
(GBE_QT_FC1004570)
PSS007610|
European Ancestry|
26,257 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Friendships satisfaction : 0.01886 [0.01682, 0.02089]
Incremental R2 (full-covars): 0.00139
PGS R2 (no covariates): 0.00143 [0.00086, 0.002]
age, sex, UKB array type, Genotype PCs
PPM007250 PGS001401
(GBE_QT_FC1004548)
PSS007601|
African Ancestry|
3,770 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Health satisfaction : 0.01436 [0.00862, 0.0201]
Incremental R2 (full-covars): -0.00107
PGS R2 (no covariates): 0.00031 [-0.00055, 0.00117]
age, sex, UKB array type, Genotype PCs
PPM007251 PGS001401
(GBE_QT_FC1004548)
PSS007602|
East Asian Ancestry|
773 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Health satisfaction : 0.01047 [0.00087, 0.02006]
Incremental R2 (full-covars): -0.00364
PGS R2 (no covariates): 0.0 [-0.0002, 0.00021]
age, sex, UKB array type, Genotype PCs
PPM007252 PGS001401
(GBE_QT_FC1004548)
PSS007603|
European Ancestry|
10,834 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Health satisfaction : 0.01053 [0.00801, 0.01305]
Incremental R2 (full-covars): 0.00325
PGS R2 (no covariates): 0.00366 [0.00217, 0.00516]
age, sex, UKB array type, Genotype PCs
PPM007253 PGS001401
(GBE_QT_FC1004548)
PSS007604|
South Asian Ancestry|
4,984 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Health satisfaction : 0.01007 [0.00567, 0.01447]
Incremental R2 (full-covars): -0.00147
PGS R2 (no covariates): 0.00014 [-0.00038, 0.00065]
age, sex, UKB array type, Genotype PCs
PPM007254 PGS001401
(GBE_QT_FC1004548)
PSS007605|
European Ancestry|
26,439 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Health satisfaction : 0.00501 [0.00394, 0.00607]
Incremental R2 (full-covars): 0.00135
PGS R2 (no covariates): 0.00204 [0.00136, 0.00272]
age, sex, UKB array type, Genotype PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS003939
[
  • 376 cases
  • , 319 controls
]
African unspecified UKB
PSS003940
[
  • 122 cases
  • , 142 controls
]
East Asian UKB
PSS003941
[
  • 3,974 cases
  • , 2,186 controls
]
European non-white British ancestry UKB
PSS003942
[
  • 526 cases
  • , 264 controls
]
South Asian UKB
PSS003943
[
  • 11,635 cases
  • , 4,850 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007591 6,303 individuals African unspecified UKB
PSS007592 1,636 individuals East Asian UKB
PSS007593 24,733 individuals European non-white British ancestry UKB
PSS007594 7,568 individuals South Asian UKB
PSS007595 67,195 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS007601 3,770 individuals African unspecified UKB
PSS007602 773 individuals East Asian UKB
PSS007603 10,834 individuals European non-white British ancestry UKB
PSS007604 4,984 individuals South Asian UKB
PSS007605 26,439 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS007606 3,707 individuals African unspecified UKB
PSS007607 782 individuals East Asian UKB
PSS007608 10,751 individuals European non-white British ancestry UKB
PSS007609 4,922 individuals South Asian UKB
PSS007610 26,257 individuals European white British ancestry UKB Testing cohort (heldout set)