Trait: whole body water mass

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009805
Description The weight of an individual's body water, i.e. the water content of a body that is contained in the tissues, the blood, the bones and elsewhere. The percentages of body water contained in various fluid compartments add up to total body water (TBW).
Trait category
Other measurement
Mapped term Wikipedia:Body_water

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001002
(GBE_INI23102)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Whole body water mass whole body water mass 35,046
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001002/ScoringFiles/PGS001002.txt.gz
PGS001984
(portability-PLR_log_water_mass)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Whole body water mass whole body water mass 127,910
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001984/ScoringFiles/PGS001984.txt.gz
PGS002202
(portability-ldpred2_log_water_mass)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Whole body water mass whole body water mass 966,737
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002202/ScoringFiles/PGS002202.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007773 PGS001002
(GBE_INI23102)
PSS005051|
African Ancestry|
6,305 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.59835 [0.58325, 0.61345]
Incremental R2 (full-covars): 0.01006
PGS R2 (no covariates): 0.01762 [0.01128, 0.02396]
age, sex, UKB array type, Genotype PCs
PPM007774 PGS001002
(GBE_INI23102)
PSS005052|
East Asian Ancestry|
1,680 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.74997 [0.72945, 0.77049]
Incremental R2 (full-covars): 0.00739
PGS R2 (no covariates): 0.0184 [0.00578, 0.03102]
age, sex, UKB array type, Genotype PCs
PPM007775 PGS001002
(GBE_INI23102)
PSS005053|
European Ancestry|
24,466 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.75696 [0.7517, 0.76221]
Incremental R2 (full-covars): 0.04635
PGS R2 (no covariates): 0.04558 [0.04052, 0.05064]
age, sex, UKB array type, Genotype PCs
PPM007776 PGS001002
(GBE_INI23102)
PSS005054|
South Asian Ancestry|
7,649 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.6942 [0.68292, 0.70548]
Incremental R2 (full-covars): 0.03631
PGS R2 (no covariates): 0.02751 [0.02037, 0.03465]
age, sex, UKB array type, Genotype PCs
PPM007777 PGS001002
(GBE_INI23102)
PSS005055|
European Ancestry|
66,264 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.75779 [0.75461, 0.76097]
Incremental R2 (full-covars): 0.05245
PGS R2 (no covariates): 0.05076 [0.04753, 0.05399]
age, sex, UKB array type, Genotype PCs
PPM010747 PGS001984
(portability-PLR_log_water_mass)
PSS009472|
European Ancestry|
19,641 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4574 [0.4462, 0.4684] sex, age, birth date, deprivation index, 16 PCs
PPM010749 PGS001984
(portability-PLR_log_water_mass)
PSS008800|
European Ancestry|
6,539 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4309 [0.4109, 0.4505] sex, age, birth date, deprivation index, 16 PCs
PPM010750 PGS001984
(portability-PLR_log_water_mass)
PSS008574|
Greater Middle Eastern Ancestry|
1,152 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3695 [0.3181, 0.4188] sex, age, birth date, deprivation index, 16 PCs
PPM010752 PGS001984
(portability-PLR_log_water_mass)
PSS008129|
East Asian Ancestry|
1,782 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3166 [0.274, 0.358] sex, age, birth date, deprivation index, 16 PCs
PPM010753 PGS001984
(portability-PLR_log_water_mass)
PSS007916|
African Ancestry|
2,420 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.2518 [0.2139, 0.2889] sex, age, birth date, deprivation index, 16 PCs
PPM010754 PGS001984
(portability-PLR_log_water_mass)
PSS009020|
African Ancestry|
3,801 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.1924 [0.1615, 0.2229] sex, age, birth date, deprivation index, 16 PCs
PPM010748 PGS001984
(portability-PLR_log_water_mass)
PSS009246|
European Ancestry|
4,073 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4477 [0.4228, 0.472] sex, age, birth date, deprivation index, 16 PCs
PPM010751 PGS001984
(portability-PLR_log_water_mass)
PSS008352|
South Asian Ancestry|
6,185 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3881 [0.3667, 0.4091] sex, age, birth date, deprivation index, 16 PCs
PPM012463 PGS002202
(portability-ldpred2_log_water_mass)
PSS009472|
European Ancestry|
19,641 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.446 [0.4347, 0.4571] sex, age, birth date, deprivation index, 16 PCs
PPM012464 PGS002202
(portability-ldpred2_log_water_mass)
PSS009246|
European Ancestry|
4,073 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4481 [0.4232, 0.4724] sex, age, birth date, deprivation index, 16 PCs
PPM012465 PGS002202
(portability-ldpred2_log_water_mass)
PSS008800|
European Ancestry|
6,539 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4242 [0.4041, 0.4439] sex, age, birth date, deprivation index, 16 PCs
PPM012466 PGS002202
(portability-ldpred2_log_water_mass)
PSS008574|
Greater Middle Eastern Ancestry|
1,152 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3643 [0.3127, 0.4138] sex, age, birth date, deprivation index, 16 PCs
PPM012467 PGS002202
(portability-ldpred2_log_water_mass)
PSS008352|
South Asian Ancestry|
6,185 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3789 [0.3573, 0.4001] sex, age, birth date, deprivation index, 16 PCs
PPM012468 PGS002202
(portability-ldpred2_log_water_mass)
PSS008129|
East Asian Ancestry|
1,782 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3154 [0.2727, 0.3569] sex, age, birth date, deprivation index, 16 PCs
PPM012469 PGS002202
(portability-ldpred2_log_water_mass)
PSS007916|
African Ancestry|
2,420 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.2493 [0.2114, 0.2865] sex, age, birth date, deprivation index, 16 PCs
PPM012470 PGS002202
(portability-ldpred2_log_water_mass)
PSS009020|
African Ancestry|
3,801 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.1924 [0.1615, 0.2229] sex, age, birth date, deprivation index, 16 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS005052 1,680 individuals East Asian UKB
PSS005053 24,466 individuals European non-white British ancestry UKB
PSS005054 7,649 individuals South Asian UKB
PSS005055 66,264 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS008800 6,539 individuals European Italy (South Europe) UKB
PSS009246 4,073 individuals European Poland (NE Europe) UKB
PSS007916 2,420 individuals African American or Afro-Caribbean Carribean UKB
PSS008352 6,185 individuals South Asian India (South Asia) UKB
PSS009020 3,801 individuals African unspecified Nigeria (West Africa) UKB
PSS008574 1,152 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009472 19,641 individuals European UK (+ Ireland) UKB
PSS008129 1,782 individuals East Asian China (East Asia) UKB
PSS005051 6,305 individuals African unspecified UKB