Trait: whole body water mass

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009805
Description The weight of an individual's body water, i.e. the water content of a body that is contained in the tissues, the blood, the bones and elsewhere. The percentages of body water contained in various fluid compartments add up to total body water (TBW).
Trait category
Other measurement
Mapped term Wikipedia:Body_water

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS001002
(GBE_INI23102)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Whole body water mass whole body water mass 35,046
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001002/ScoringFiles/PGS001002.txt.gz
PGS001984
(portability-PLR_log_water_mass)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Whole body water mass whole body water mass 127,910
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001984/ScoringFiles/PGS001984.txt.gz
PGS002202
(portability-ldpred2_log_water_mass)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Whole body water mass whole body water mass 966,737
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002202/ScoringFiles/PGS002202.txt.gz
PGS003540
(cont-decay-log_impedance)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Impedance of whole body whole body water mass 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003540/ScoringFiles/PGS003540.txt.gz
PGS003556
(cont-decay-log_water_mass)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Whole body water mass whole body water mass 979,739
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003556/ScoringFiles/PGS003556.txt.gz
PGS003902
(INI23102)
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Whole body water mass whole body water mass 43,166
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003902/ScoringFiles/PGS003902.txt.gz
PGS004377
(X23102.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Whole body water mass whole body water mass 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004377/ScoringFiles/PGS004377.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007773 PGS001002
(GBE_INI23102)
PSS005051|
African Ancestry|
6,305 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.59835 [0.58325, 0.61345]
Incremental R2 (full-covars): 0.01006
PGS R2 (no covariates): 0.01762 [0.01128, 0.02396]
age, sex, UKB array type, Genotype PCs
PPM007774 PGS001002
(GBE_INI23102)
PSS005052|
East Asian Ancestry|
1,680 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.74997 [0.72945, 0.77049]
Incremental R2 (full-covars): 0.00739
PGS R2 (no covariates): 0.0184 [0.00578, 0.03102]
age, sex, UKB array type, Genotype PCs
PPM007775 PGS001002
(GBE_INI23102)
PSS005053|
European Ancestry|
24,466 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.75696 [0.7517, 0.76221]
Incremental R2 (full-covars): 0.04635
PGS R2 (no covariates): 0.04558 [0.04052, 0.05064]
age, sex, UKB array type, Genotype PCs
PPM007776 PGS001002
(GBE_INI23102)
PSS005054|
South Asian Ancestry|
7,649 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.6942 [0.68292, 0.70548]
Incremental R2 (full-covars): 0.03631
PGS R2 (no covariates): 0.02751 [0.02037, 0.03465]
age, sex, UKB array type, Genotype PCs
PPM007777 PGS001002
(GBE_INI23102)
PSS005055|
European Ancestry|
66,264 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Whole body water mass : 0.75779 [0.75461, 0.76097]
Incremental R2 (full-covars): 0.05245
PGS R2 (no covariates): 0.05076 [0.04753, 0.05399]
age, sex, UKB array type, Genotype PCs
PPM010747 PGS001984
(portability-PLR_log_water_mass)
PSS009472|
European Ancestry|
19,641 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4574 [0.4462, 0.4684] sex, age, birth date, deprivation index, 16 PCs
PPM010749 PGS001984
(portability-PLR_log_water_mass)
PSS008800|
European Ancestry|
6,539 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4309 [0.4109, 0.4505] sex, age, birth date, deprivation index, 16 PCs
PPM010750 PGS001984
(portability-PLR_log_water_mass)
PSS008574|
Greater Middle Eastern Ancestry|
1,152 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3695 [0.3181, 0.4188] sex, age, birth date, deprivation index, 16 PCs
PPM010752 PGS001984
(portability-PLR_log_water_mass)
PSS008129|
East Asian Ancestry|
1,782 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3166 [0.274, 0.358] sex, age, birth date, deprivation index, 16 PCs
PPM010753 PGS001984
(portability-PLR_log_water_mass)
PSS007916|
African Ancestry|
2,420 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.2518 [0.2139, 0.2889] sex, age, birth date, deprivation index, 16 PCs
PPM010754 PGS001984
(portability-PLR_log_water_mass)
PSS009020|
African Ancestry|
3,801 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.1924 [0.1615, 0.2229] sex, age, birth date, deprivation index, 16 PCs
PPM010748 PGS001984
(portability-PLR_log_water_mass)
PSS009246|
European Ancestry|
4,073 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4477 [0.4228, 0.472] sex, age, birth date, deprivation index, 16 PCs
PPM010751 PGS001984
(portability-PLR_log_water_mass)
PSS008352|
South Asian Ancestry|
6,185 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3881 [0.3667, 0.4091] sex, age, birth date, deprivation index, 16 PCs
PPM012463 PGS002202
(portability-ldpred2_log_water_mass)
PSS009472|
European Ancestry|
19,641 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.446 [0.4347, 0.4571] sex, age, birth date, deprivation index, 16 PCs
PPM012464 PGS002202
(portability-ldpred2_log_water_mass)
PSS009246|
European Ancestry|
4,073 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4481 [0.4232, 0.4724] sex, age, birth date, deprivation index, 16 PCs
PPM012465 PGS002202
(portability-ldpred2_log_water_mass)
PSS008800|
European Ancestry|
6,539 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.4242 [0.4041, 0.4439] sex, age, birth date, deprivation index, 16 PCs
PPM012466 PGS002202
(portability-ldpred2_log_water_mass)
PSS008574|
Greater Middle Eastern Ancestry|
1,152 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3643 [0.3127, 0.4138] sex, age, birth date, deprivation index, 16 PCs
PPM012467 PGS002202
(portability-ldpred2_log_water_mass)
PSS008352|
South Asian Ancestry|
6,185 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3789 [0.3573, 0.4001] sex, age, birth date, deprivation index, 16 PCs
PPM012468 PGS002202
(portability-ldpred2_log_water_mass)
PSS008129|
East Asian Ancestry|
1,782 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.3154 [0.2727, 0.3569] sex, age, birth date, deprivation index, 16 PCs
PPM012469 PGS002202
(portability-ldpred2_log_water_mass)
PSS007916|
African Ancestry|
2,420 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.2493 [0.2114, 0.2865] sex, age, birth date, deprivation index, 16 PCs
PPM012470 PGS002202
(portability-ldpred2_log_water_mass)
PSS009020|
African Ancestry|
3,801 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Whole body water mass Partial Correlation (partial-r): 0.1924 [0.1615, 0.2229] sex, age, birth date, deprivation index, 16 PCs
PPM017552 PGS003540
(cont-decay-log_impedance)
PSS010821|
European Ancestry|
4,059 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Impedance of whole body partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017468 PGS003540
(cont-decay-log_impedance)
PSS010905|
European Ancestry|
19,653 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Impedance of whole body partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017636 PGS003540
(cont-decay-log_impedance)
PSS010653|
European Ancestry|
6,373 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Impedance of whole body partial-R2: 0.15 sex, age, deprivation index, PC1-16
PPM017720 PGS003540
(cont-decay-log_impedance)
PSS010569|
Greater Middle Eastern Ancestry|
1,123 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Impedance of whole body partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017804 PGS003540
(cont-decay-log_impedance)
PSS010233|
European Ancestry|
2,316 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Impedance of whole body partial-R2: 0.16 sex, age, deprivation index, PC1-16
PPM017888 PGS003540
(cont-decay-log_impedance)
PSS010485|
South Asian Ancestry|
6,127 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Impedance of whole body partial-R2: 0.13 sex, age, deprivation index, PC1-16
PPM017972 PGS003540
(cont-decay-log_impedance)
PSS010401|
East Asian Ancestry|
1,770 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Impedance of whole body partial-R2: 0.08 sex, age, deprivation index, PC1-16
PPM018056 PGS003540
(cont-decay-log_impedance)
PSS010317|
African Ancestry|
2,405 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Impedance of whole body partial-R2: 0.06 sex, age, deprivation index, PC1-16
PPM018140 PGS003540
(cont-decay-log_impedance)
PSS010737|
African Ancestry|
3,770 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Impedance of whole body partial-R2: 0.03 sex, age, deprivation index, PC1-16
PPM017484 PGS003556
(cont-decay-log_water_mass)
PSS010922|
European Ancestry|
19,662 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Whole body water mass partial-R2: 0.2 sex, age, deprivation index, PC1-16
PPM017568 PGS003556
(cont-decay-log_water_mass)
PSS010838|
European Ancestry|
4,063 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Whole body water mass partial-R2: 0.2 sex, age, deprivation index, PC1-16
PPM017652 PGS003556
(cont-decay-log_water_mass)
PSS010670|
European Ancestry|
6,377 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Whole body water mass partial-R2: 0.18 sex, age, deprivation index, PC1-16
PPM017736 PGS003556
(cont-decay-log_water_mass)
PSS010586|
Greater Middle Eastern Ancestry|
1,124 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Whole body water mass partial-R2: 0.15 sex, age, deprivation index, PC1-16
PPM017820 PGS003556
(cont-decay-log_water_mass)
PSS010250|
European Ancestry|
2,318 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Whole body water mass partial-R2: 0.19 sex, age, deprivation index, PC1-16
PPM018072 PGS003556
(cont-decay-log_water_mass)
PSS010334|
African Ancestry|
2,408 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Whole body water mass partial-R2: 0.07 sex, age, deprivation index, PC1-16
PPM018156 PGS003556
(cont-decay-log_water_mass)
PSS010754|
African Ancestry|
3,773 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Whole body water mass partial-R2: 0.03 sex, age, deprivation index, PC1-16
PPM017904 PGS003556
(cont-decay-log_water_mass)
PSS010502|
South Asian Ancestry|
6,134 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Whole body water mass partial-R2: 0.15 sex, age, deprivation index, PC1-16
PPM017988 PGS003556
(cont-decay-log_water_mass)
PSS010418|
East Asian Ancestry|
1,770 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Whole body water mass partial-R2: 0.09 sex, age, deprivation index, PC1-16
PPM018829 PGS003902
(INI23102)
PSS011120|
European Ancestry|
66,617 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass : 0.76001 [0.75686, 0.76316]
PGS R2 (no covariates): 0.0537 [0.0504, 0.057]
Incremental R2 (full-covars): 0.0541
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018830 PGS003902
(INI23102)
PSS011105|
European Ancestry|
2,837 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass : 0.75815 [0.74282, 0.77347]
PGS R2 (no covariates): 0.0659 [0.04845, 0.08335]
Incremental R2 (full-covars): 0.05792
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018831 PGS003902
(INI23102)
PSS011118|
South Asian Ancestry|
1,457 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass : 0.69263 [0.66668, 0.71857]
PGS R2 (no covariates): 0.02973 [0.01276, 0.04669]
Incremental R2 (full-covars): 0.04434
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018832 PGS003902
(INI23102)
PSS011158|
African Ancestry|
1,169 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass : 0.58375 [0.54806, 0.61944]
PGS R2 (no covariates): 0.00794 [-0.00198, 0.01785]
Incremental R2 (full-covars): 0.00256
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM018833 PGS003902
(INI23102)
PSS011176|
Multi-ancestry (excluding European)|
7,842 individuals
PGP000502 |
Tanigawa Y et al. AJHG (2023)
Reported Trait: Whole body water mass : 0.74875 [0.73923, 0.75827]
PGS R2 (no covariates): 0.03942 [0.03107, 0.04777]
Incremental R2 (full-covars): 0.0395
age, sex, age^2, age*sex, Townsend deprivation index, genotype PCs (PC1-PC18)
PPM020492 PGS004377
(X23102.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: Whole body water mass PGS R2 (no covariates): 0.21586

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS005052 1,680 individuals East Asian UKB
PSS005053 24,466 individuals European non-white British ancestry UKB
PSS005054 7,649 individuals South Asian UKB
PSS005055 66,264 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS010401 1,770 individuals,
34.0 % Male samples
Mean = 52.4 years
Sd = 7.7 years
East Asian Chinese UKB
PSS010922 19,662 individuals,
46.0 % Male samples
Mean = 56.9 years
Sd = 7.9 years
European white British UKB
PSS010670 6,377 individuals,
45.0 % Male samples
Mean = 54.5 years
Sd = 8.4 years
European Italian UKB
PSS011158 1,169 individuals African unspecified UKB
PSS010418 1,770 individuals,
34.0 % Male samples
Mean = 52.4 years
Sd = 7.7 years
East Asian Chinese UKB
PSS008800 6,539 individuals European Italy (South Europe) UKB
PSS011176 7,842 individuals East Asian, Other admixed ancestry East Asian, Other admixed ancestry UKB
PSS010821 4,059 individuals,
38.0 % Male samples
Mean = 54.3 years
Sd = 7.5 years
European Polish UKB
PSS007916 2,420 individuals African American or Afro-Caribbean Carribean UKB
PSS010569 1,123 individuals,
60.0 % Male samples
Mean = 52.0 years
Sd = 7.9 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB
PSS010317 2,405 individuals,
36.0 % Male samples
Mean = 52.4 years
Sd = 8.1 years
African American or Afro-Caribbean Caribbean UKB
PSS005051 6,305 individuals African unspecified UKB
PSS010838 4,063 individuals,
38.0 % Male samples
Mean = 54.3 years
Sd = 7.5 years
European Polish UKB
PSS008574 1,152 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009472 19,641 individuals European UK (+ Ireland) UKB
PSS010586 1,124 individuals,
60.0 % Male samples
Mean = 52.0 years
Sd = 7.9 years
Greater Middle Eastern (Middle Eastern, North African or Persian) Iranian UKB
PSS010334 2,408 individuals,
36.0 % Male samples
Mean = 52.5 years
Sd = 8.1 years
African American or Afro-Caribbean Caribbean UKB
PSS010737 3,770 individuals,
46.0 % Male samples
Mean = 51.9 years
Sd = 8.1 years
African unspecified Nigerian UKB
PSS010485 6,127 individuals,
54.0 % Male samples
Mean = 53.3 years
Sd = 8.4 years
South Asian Indian UKB
PSS009246 4,073 individuals European Poland (NE Europe) UKB
PSS010233 2,316 individuals,
45.0 % Male samples
Mean = 58.1 years
Sd = 7.1 years
European Ashkenazi UKB
PSS008352 6,185 individuals South Asian India (South Asia) UKB
PSS011105 2,837 individuals European
(non-white British ancestry)
UKB
PSS011364 56,192 individuals European UKB
PSS010754 3,773 individuals,
46.0 % Male samples
Mean = 51.9 years
Sd = 8.1 years
African unspecified Nigerian UKB
PSS010502 6,134 individuals,
54.0 % Male samples
Mean = 53.3 years
Sd = 8.4 years
South Asian Indian UKB
PSS011118 1,457 individuals South Asian UKB
PSS010250 2,318 individuals,
45.0 % Male samples
Mean = 58.0 years
Sd = 7.1 years
European Ashkenazi UKB
PSS011120 66,617 individuals European
(white British ancestry)
UKB
PSS009020 3,801 individuals African unspecified Nigeria (West Africa) UKB
PSS010905 19,653 individuals,
46.0 % Male samples
Mean = 56.9 years
Sd = 7.9 years
European white British UKB
PSS008129 1,782 individuals East Asian China (East Asia) UKB
PSS010653 6,373 individuals,
45.0 % Male samples
Mean = 54.5 years
Sd = 8.4 years
European Italian UKB