Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004720
(AST_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Aspartate aminotransferase level aspartate aminotransferase measurement 1,000,300
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004720/ScoringFiles/PGS004720.txt.gz
PGS004608
(neuroticism)
 PGP000584 |
Forthman KL et al. J Psychiatr Res (2023)
 Neuroticism neuroticism measurement 1,000,537
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004608/ScoringFiles/PGS004608.txt.gz
PGS004606
(AMD-IAMDGC-EUR)
 PGP000582 |
Gorman BR et al. Nat Genet (2024)
 Age-related macular degeneration age-related macular degeneration 1,000,946
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004606/ScoringFiles/PGS004606.txt.gz
PGS003444
(PRScsx_T2D_LAT_EASweights)
 PGP000445 |
Huerta-Chagoya A et al. Diabetologia (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,001,579
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003444/ScoringFiles/PGS003444.txt.gz
PGS005293
(Jorda_CAD_MTAG-PGS_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Coronary artery disease coronary artery disease 1,003,984
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005293/ScoringFiles/PGS005293.txt.gz
PGS005294
(Jorda_CAD_MTAG-PGS_females_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Coronary artery disease coronary artery disease 1,003,984
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005294/ScoringFiles/PGS005294.txt.gz
PGS005295
(Jorda_CAD_MTAG-PGS_males_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Coronary artery disease coronary artery disease 1,003,984
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005295/ScoringFiles/PGS005295.txt.gz
PGS003990
(dbslmm.auto.GCST008972.Gout)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Gout gout 1,005,456
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003990/ScoringFiles/PGS003990.txt.gz
PGS003991
(dbslmm.auto.GCST008972.Urate)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Urate urate measurement 1,005,456
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003991/ScoringFiles/PGS003991.txt.gz
PGS004161
(UKBB_EnsPGS.GCST008972.Urate)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Urate urate measurement 1,005,478
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004161/ScoringFiles/PGS004161.txt.gz
PGS003262
(ExPRSweb_Creatine_eGFRcrea-overall-IV-2GC_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Creatine) glomerular filtration rate,
creatine level		 1,005,540
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003262/ScoringFiles/PGS003262.txt.gz
PGS005131
(forEUR_fromAFR)
 PGP000703 |
Tsuo K et al. Cell Genom (2022)
 Asthma asthma 1,005,883
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005131/ScoringFiles/PGS005131.txt.gz
PGS002933
(ExPRSweb_FPG_MAGIC-FastingGlucose_PRSCS_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Fasting plasma glucose blood glucose amount 1,007,415
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002933/ScoringFiles/PGS002933.txt.gz
PGS002953
(ExPRSweb_Glucose_MAGIC-FastingGlucose_PRSCS_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Glucose blood glucose amount 1,008,035
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002953/ScoringFiles/PGS002953.txt.gz
PGS005121
(forAFR_fromAFR)
 PGP000703 |
Tsuo K et al. Cell Genom (2022)
 Asthma asthma 1,008,855
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005121/ScoringFiles/PGS005121.txt.gz
PGS003987
(dbslmm.auto.GCST007954.HbA1c)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 HbA1c HbA1c measurement 1,009,642
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003987/ScoringFiles/PGS003987.txt.gz
PGS004157
(UKBB_EnsPGS.GCST007954.HbA1c)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 HbA1c HbA1c measurement 1,009,664
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004157/ScoringFiles/PGS004157.txt.gz
PGS003868
(CM_LDpred2_ARB)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 Cardiomyopathy cardiomyopathy 1,010,014
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003868/ScoringFiles/PGS003868.txt.gz
PGS004041
(ldpred2.CV.GCST005838.Stroke)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Stroke stroke 1,011,468
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004041/ScoringFiles/PGS004041.txt.gz
PGS004026
(ldpred2.auto.GCST005838.Stroke)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Stroke stroke 1,011,468
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004026/ScoringFiles/PGS004026.txt.gz
PGS004080
(prscs.auto.GCST002783.BMI)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Body mass index (BMI) body mass index 1,011,571
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004080/ScoringFiles/PGS004080.txt.gz
PGS004096
(prscs.CV.GCST002783.BMI)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Body mass index (BMI) body mass index 1,011,571
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004096/ScoringFiles/PGS004096.txt.gz
PGS003852
(CRC_PRS_EUR_EAS)
 PGP000492 |
Thomas M et al. Nat Commun (2023)
 Colorectal cancer colorectal cancer 1,016,596
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003852/ScoringFiles/PGS003852.txt.gz
PGS005288
(Jorda_AF_MTAG-PGS_females_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Atrial fibrillation atrial fibrillation 1,016,634
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005288/ScoringFiles/PGS005288.txt.gz
PGS005289
(Jorda_AF_MTAG-PGS_males_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Atrial fibrillation atrial fibrillation 1,016,634
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005289/ScoringFiles/PGS005289.txt.gz
PGS005287
(Jorda_AF_MTAG-PGS_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Atrial fibrillation atrial fibrillation 1,016,634
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005287/ScoringFiles/PGS005287.txt.gz
PGS004694
(prostate_cancer)
 PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
 Prostate cancer prostate carcinoma 1,016,708
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004694/ScoringFiles/PGS004694.txt.gz
PGS004023
(ldpred2.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,018,068
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004023/ScoringFiles/PGS004023.txt.gz
PGS004038
(ldpred2.CV.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,018,068
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004038/ScoringFiles/PGS004038.txt.gz
PGS001352
(MAGICTA_EUR_PGS_HbA1c)
 PGP000246 |
Chen J et al. Nat Genet (2021)
 Glycated haemoglobin levels (HbA1c) HbA1c measurement 1,018,836
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001352/ScoringFiles/PGS001352.txt.gz
PGS005201
(G23_BMI_2025_PRSCSx_LC_AMR)
 PGP000724 |
Smit RAJ et al. Nat Med (2025)
 Body mass index (BMI) body mass index 1,020,295
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005201/ScoringFiles/PGS005201.txt.gz - Check Terms/Licenses
PGS005245
(T2D_PRS_PRS_CSx_META_F_EAS)
 PGP000742 |
Guo B G et al. Nat Commun (2025)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,021,829
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005245/ScoringFiles/PGS005245.txt.gz
PGS003875
(HDL_PRScsx_ARB_AFRweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 1,022,259
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003875/ScoringFiles/PGS003875.txt.gz
PGS003869
(LDL_PRScsx_ARB_AFRweights)
 PGP000501 |
Shim I et al. Nature Communications (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,022,259
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003869/ScoringFiles/PGS003869.txt.gz
PGS005114
(PGS_BMI)
 PGP000701 |
Loesch DP et al. Nat Commun (2025)
 Body mass index (BMI) body mass index 1,022,364
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005114/ScoringFiles/PGS005114.txt.gz
PGS005202
(G23_BMI_2025_PRSCSx_LC_EAS)
 PGP000724 |
Smit RAJ et al. Nat Med (2025)
 Body mass index (BMI) body mass index 1,022,487
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005202/ScoringFiles/PGS005202.txt.gz - Check Terms/Licenses
PGS005350
(SBP)
 PGP000772 |
Øvretveit K et al. Eur J Prev Cardiol (2024)
 Systolic blood pressure systolic blood pressure 1,022,624
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005350/ScoringFiles/PGS005350.txt.gz
PGS005352
(PP)
 PGP000772 |
Øvretveit K et al. Eur J Prev Cardiol (2024)
 Pulse Pressure pulse pressure measurement 1,022,643
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005352/ScoringFiles/PGS005352.txt.gz
PGS001350
(MAGICTA_EUR_PGS_FG)
 PGP000246 |
Chen J et al. Nat Genet (2021)
 Fasting glucose blood glucose amount 1,023,373
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001350/ScoringFiles/PGS001350.txt.gz
PGS005351
(DBP)
 PGP000772 |
Øvretveit K et al. Eur J Prev Cardiol (2024)
 Diastolic blood pressure diastolic blood pressure 1,024,311
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005351/ScoringFiles/PGS005351.txt.gz
PGS001351
(MAGICTA_EUR_PGS_FI)
 PGP000246 |
Chen J et al. Nat Genet (2021)
 Fasting insulin blood insulin amount 1,025,098
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001351/ScoringFiles/PGS001351.txt.gz
PGS000890
(GLGC_2021_EAS_LDL_PRS_weights_PRS-CS)
 PGP000230 |
Graham SE et al. Nature (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 1,029,158
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000890/ScoringFiles/PGS000890.txt.gz
PGS003589
(UKB_cycproduction_EUR)
 PGP000463 |
Kleeman SO et al. Cell Genom (2023)
 Cystatin C production cystatin C measurement 1,031,527
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003589/ScoringFiles/PGS003589.txt.gz
PGS004949
(DCM_MTAG_exclUKB)
 PGP000672 |
Jurgens SJ et al. Nat Genet (2024)
 Dilated cardiomyopathy (MTAG) dilated cardiomyopathy 1,038,394
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004949/ScoringFiles/PGS004949.txt.gz
PGS003980
(dbslmm.auto.GCST002783.BMI)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Body mass index (BMI) body mass index 1,039,020
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003980/ScoringFiles/PGS003980.txt.gz
PGS004150
(UKBB_EnsPGS.GCST002783.BMI)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Body mass index (BMI) body mass index 1,039,042
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004150/ScoringFiles/PGS004150.txt.gz
PGS004040
(ldpred2.CV.GCST004988.Breast_cancer)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Breast cancer breast carcinoma 1,041,298
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004040/ScoringFiles/PGS004040.txt.gz
PGS004025
(ldpred2.auto.GCST004988.Breast_cancer)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Breast cancer breast carcinoma 1,041,298
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004025/ScoringFiles/PGS004025.txt.gz
PGS005296
(Jorda_CAD_SingleTrait-PGS_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Coronary artery disease coronary artery disease 1,042,395
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005296/ScoringFiles/PGS005296.txt.gz
PGS005297
(Jorda_CAD_SingleTrait-PGS_females_2024)
 PGP000759 |
Jordà P et al. NPJ Genom Med (2025)
 Coronary artery disease coronary artery disease 1,042,395
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005297/ScoringFiles/PGS005297.txt.gz
Showing 4001 to 4050 of 5221 rows