Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000058
(CAD_GRS_204)
 PGP000043 |
Morieri ML et al. Diabetes Care (2018)
 Coronary artery disease coronary artery disease 204
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000058/ScoringFiles/PGS000058.txt.gz
PGS001312
(GBE_HC38)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Psoriasis psoriasis 204
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001312/ScoringFiles/PGS001312.txt.gz
PGS003301
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 204
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003301/ScoringFiles/PGS003301.txt.gz
PGS003300
(ExPRSweb_CysC_eGFRcys-overall-IV-2GC_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 203
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003300/ScoringFiles/PGS003300.txt.gz
PGS000847
(TG)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Triglycerides (TG) triglyceride measurement 201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000847/ScoringFiles/PGS000847.txt.gz
PGS002616
(cov_SMOKING_STATUS.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Smoking status smoking status measurement 201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002616/ScoringFiles/PGS002616.txt.gz
PGS003672
(L_hippocampal_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal head volume hippocampal volume 201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003672/ScoringFiles/PGS003672.txt.gz
PGS000817
(GRS200_GGT)
 PGP000201 |
Pazoki R et al. Nat Commun (2021)
 Gamma-glutamyl transferase serum gamma-glutamyl transferase measurement 200
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000817/ScoringFiles/PGS000817.txt.gz
PGS001730
(GBE_INI25625)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA L3 in tract anterior thalamic radiation (L) neuroimaging measurement,
brain volume		 200
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001730/ScoringFiles/PGS001730.txt.gz
PGS004109
(pt_clump.auto.GCST006085.Prostate_cancer)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Prostate cancer prostate carcinoma 200
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004109/ScoringFiles/PGS004109.txt.gz
PGS004262
(GenoBoost_psoriasis_2)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Psoriasis psoriasis 200
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004262/ScoringFiles/PGS004262.txt.gz
PGS004266
(GenoBoost_gout_1)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Gout gout 200
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004266/ScoringFiles/PGS004266.txt.gz
PGS004288
(GenoBoost_alzheimer_s_disease_3)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 200
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004288/ScoringFiles/PGS004288.txt.gz
PGS004303
(GenoBoost_colorectal_cancer_3)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Colorectal cancer colorectal carcinoma 200
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004303/ScoringFiles/PGS004303.txt.gz
PGS003769
(HDL_AFR_CT)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 198
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003769/ScoringFiles/PGS003769.txt.gz
PGS001699
(GBE_INI25726)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA ISOVF in tract superior longitudinal fasciculus (R) neuroimaging measurement,
brain volume		 197
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001699/ScoringFiles/PGS001699.txt.gz
PGS003663
(L_hippocampus_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampus volume hippocampal volume 197
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003663/ScoringFiles/PGS003663.txt.gz
PGS002610
(mental_NEUROTICISM.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Neuroticism neuroticism measurement 196
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002610/ScoringFiles/PGS002610.txt.gz
PGS001288
(GBE_HC95)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Inflammatory bowel disease inflammatory bowel disease 195
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001288/ScoringFiles/PGS001288.txt.gz
PGS001337
(GBE_FH1002)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Family history of breast cancer family history of breast cancer 195
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001337/ScoringFiles/PGS001337.txt.gz
PGS000310
(GRS194_LDL)
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 LDL cholesterol low density lipoprotein cholesterol measurement 194
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000310/ScoringFiles/PGS000310.txt.gz
PGS001548
(GBE_INI25864)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Volume of grey matter in Central Opercular Cortex (L) neuroimaging measurement,
grey matter volume measurement		 194
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001548/ScoringFiles/PGS001548.txt.gz
PGS003120
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 193
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003120/ScoringFiles/PGS003120.txt.gz
PGS003121
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 193
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003121/ScoringFiles/PGS003121.txt.gz
PGS000019
(GRS_CAD)
 PGP000009 |
Paquette M et al. J Clin Lipidol (2017)
 Coronary artery disease coronary artery disease 192
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000019/ScoringFiles/PGS000019.txt.gz
PGS001852
(portability-PLR_535.6)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Duodenitis duodenitis 191
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001852/ScoringFiles/PGS001852.txt.gz
PGS000312
(GRS190_TG)
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 Triglycerides triglyceride measurement 190
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000312/ScoringFiles/PGS000312.txt.gz
PGS003619
(R_CA1_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right CA1 body volume hippocampal CA1 volume 189
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003619/ScoringFiles/PGS003619.txt.gz
PGS001465
(GBE_INI25349)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Mean ICVF in fornix on FA skeleton neuroimaging measurement,
brain volume		 188
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001465/ScoringFiles/PGS001465.txt.gz
PGS003786
(LDL_AFR_CT)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 188
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003786/ScoringFiles/PGS003786.txt.gz
PGS000072
(CC_Breast)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Breast cancer breast carcinoma 187
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000072/ScoringFiles/PGS000072.txt.gz
PGS001659
(GBE_INI25513)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA FA in tract uncinate fasciculus (L) neuroimaging measurement,
brain volume		 187
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001659/ScoringFiles/PGS001659.txt.gz
PGS001820
(portability-PLR_251.1)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hypoglycemia Hypoglycemia 187
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001820/ScoringFiles/PGS001820.txt.gz
PGS002592
(disease_ENDOCRINE_DIABETES.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Endocrine and diabetes diseases diabetes mellitus,
endocrine system disease		 187
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002592/ScoringFiles/PGS002592.txt.gz
PGS003105
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 187
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003105/ScoringFiles/PGS003105.txt.gz
PGS003106
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 187
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003106/ScoringFiles/PGS003106.txt.gz
PGS004864
(PRS186_BMI)
 PGP000611 |
de Toro-Martín J et al. JCI Insight (2018)
 Body mass index (BMI) body mass index 186
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004864/ScoringFiles/PGS004864.txt.gz
PGS000163
(baso)
 PGP000078 |
Vuckovic D et al. Cell (2020)
 Basophil count basophil count 185
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000163/ScoringFiles/PGS000163.txt.gz
PGS000411
(PRSWEB_PHECODE172.1_20001-1059_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 185
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000411/ScoringFiles/PGS000411.txt.gz
PGS001276
(GBE_HC881)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Retinal disorders in diseases classified elsewhere (time-to-event) retinopathy 185
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001276/ScoringFiles/PGS001276.txt.gz
PGS001611
(GBE_INI25896)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Volume of grey matter in V Cerebellum (R) neuroimaging measurement,
grey matter volume measurement		 184
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001611/ScoringFiles/PGS001611.txt.gz
PGS000448
(PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 183
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000448/ScoringFiles/PGS000448.txt.gz
PGS003728
(PS_T2D_183-AGEN)
 PGP000469 |
Wedekind LE et al. Diabetologia (2023)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 183
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003728/ScoringFiles/PGS003728.txt.gz
PGS004912
(PRS183)
 PGP000643 |
Tian J et al. Genome Med (2024)
 Colorectal neoplasm colorectal carcinoma 183
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004912/ScoringFiles/PGS004912.txt.gz
PGS000317
(PRS180)
 PGP000094 |
Shieh Y et al. J Natl Cancer Inst (2020)
 Breast cancer breast carcinoma 180
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000317/ScoringFiles/PGS000317.txt.gz
PGS000356
(PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Any cancer cancer 179
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000356/ScoringFiles/PGS000356.txt.gz
PGS000773
(PRS179_BC)
 PGP000179 |
Du Z et al. J Natl Cancer Inst (2021)
 Breast cancer breast carcinoma 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000773/ScoringFiles/PGS000773.txt.gz
PGS000774
(PRS179_ERpos)
 PGP000179 |
Du Z et al. J Natl Cancer Inst (2021)
 Estrogen receptor positive breast cancer estrogen-receptor positive breast cancer 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000774/ScoringFiles/PGS000774.txt.gz
PGS000775
(PRS179_ERneg)
 PGP000179 |
Du Z et al. J Natl Cancer Inst (2021)
 Estrogen receptor negative breast cancer estrogen-receptor negative breast cancer 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000775/ScoringFiles/PGS000775.txt.gz
PGS001306
(GBE_HC201)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ulcerative colitis ulcerative colitis 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001306/ScoringFiles/PGS001306.txt.gz
Showing 4251 to 4300 of 5296 rows