Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS003048
(ExPRSweb_Smoking_20116-1_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Smoking status smoking status measurement 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003048/ScoringFiles/PGS003048.txt.gz
PGS003053
(ExPRSweb_Smoking_20116-2_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Smoking status smoking status measurement 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003053/ScoringFiles/PGS003053.txt.gz
PGS003058
(ExPRSweb_Smoking_20160_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Smoking status smoking status measurement 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003058/ScoringFiles/PGS003058.txt.gz
PGS003093
(ExPRSweb_T2D_2443_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003093/ScoringFiles/PGS003093.txt.gz
PGS003233
(ExPRSweb_Creatine_30510-irnt_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Creatine creatine measurement 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003233/ScoringFiles/PGS003233.txt.gz
PGS003238
(ExPRSweb_Creatine_30510-raw_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Creatine creatine measurement 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003238/ScoringFiles/PGS003238.txt.gz
PGS003323
(ExPRSweb_Insomnia_1160_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003323/ScoringFiles/PGS003323.txt.gz
PGS000561
(PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of ovary ovarian neoplasm 1,114,056
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000561/ScoringFiles/PGS000561.txt.gz
PGS003293
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
1,114,109
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003293/ScoringFiles/PGS003293.txt.gz
PGS002888
(ExPRSweb_CRP_prot-a-670_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
C-reactive protein C-reactive protein measurement 1,114,754
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002888/ScoringFiles/PGS002888.txt.gz
PGS003308
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
1,114,999
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003308/ScoringFiles/PGS003308.txt.gz
PGS000557
(PRSWEB_PHECODE184.11_Phelan-OCCC_PRS-CS_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of ovary ovarian neoplasm 1,115,187
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000557/ScoringFiles/PGS000557.txt.gz
PGS000546
(PRSWEB_PHECODE184.11_Phelan-ENOC_PRS-CS_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of ovary ovarian neoplasm 1,115,189
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000546/ScoringFiles/PGS000546.txt.gz
PGS000550
(PRSWEB_PHECODE184.11_Phelan-IEOC_PRS-CS_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of ovary ovarian neoplasm 1,115,189
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000550/ScoringFiles/PGS000550.txt.gz
PGS000554
(PRSWEB_PHECODE184.11_Phelan-LSASBOC_PRS-CS_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of ovary ovarian neoplasm 1,115,189
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000554/ScoringFiles/PGS000554.txt.gz
PGS000562
(PRSWEB_PHECODE184.11_Phelan-SIOC_PRS-CS_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of ovary ovarian neoplasm 1,115,189
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000562/ScoringFiles/PGS000562.txt.gz
PGS000519
(PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 1,115,376
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000519/ScoringFiles/PGS000519.txt.gz
PGS000527
(PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 1,115,436
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000527/ScoringFiles/PGS000527.txt.gz
PGS000535
(PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 1,115,484
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000535/ScoringFiles/PGS000535.txt.gz
PGS003971
(HARE_META_SBP_PRS_FEMALE)
PGP000512 |
Shetty NS et al. Circ Genom Precis Med (2023)
Systolic blood pressure systolic blood pressure 1,115,520
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003971/ScoringFiles/PGS003971.txt.gz
PGS003970
(HARE_META_SBP_PRS_MALE)
PGP000512 |
Shetty NS et al. Circ Genom Precis Med (2023)
Systolic blood pressure systolic blood pressure 1,115,602
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003970/ScoringFiles/PGS003970.txt.gz
PGS003098
(ExPRSweb_T2D_29358691-GCST005413_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,116,101
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003098/ScoringFiles/PGS003098.txt.gz
PGS003043
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Polyunsatturated fatty acids polyunsaturated fatty acid measurement 1,116,151
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003043/ScoringFiles/PGS003043.txt.gz
PGS003128
(ExPRSweb_Thinness_STILTS-UKHLS_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Thinness body mass index 1,116,425
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003128/ScoringFiles/PGS003128.txt.gz
PGS000520
(PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PRS-CS_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 1,116,435
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000520/ScoringFiles/PGS000520.txt.gz
PGS000528
(PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PRS-CS_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 1,116,495
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000528/ScoringFiles/PGS000528.txt.gz
PGS002834
(ExPRSweb_Alcohol_DrinksPerWeek_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Alcohol consumption alcohol consumption measurement 1,116,497
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002834/ScoringFiles/PGS002834.txt.gz
PGS000536
(PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PRS-CS_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 1,116,546
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000536/ScoringFiles/PGS000536.txt.gz
PGS004154
(UKBB_EnsPGS.GCST005838.Stroke)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Stroke stroke 1,116,976
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004154/ScoringFiles/PGS004154.txt.gz
PGS003113
(ExPRSweb_T2D_29358691-GCST005413_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,117,087
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003113/ScoringFiles/PGS003113.txt.gz
PGS003223
(ExPRSweb_eGFR_20171017-MW-eGFR-EA_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate glomerular filtration rate 1,117,334
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003223/ScoringFiles/PGS003223.txt.gz
PGS004889
(CKD_gePGS)
PGP000619 |
Mandla R et al. Genome Med (2024)
Chronic kidney disease chronic kidney disease 1,117,375
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004889/ScoringFiles/PGS004889.txt.gz
PGS002839
(ExPRSweb_Alcohol_DrinksPerWeek_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Alcohol consumption alcohol consumption measurement 1,117,376
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002839/ScoringFiles/PGS002839.txt.gz
PGS004612
(PRSECG_AI)
PGP000591 |
Wang X et al. Circ Genom Precis Med (2023)
ECG-AI predicted 5-year risk of atrial fibrillation atrial fibrillation 1,117,399
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004612/ScoringFiles/PGS004612.txt.gz
PGS004613
(PRSCHARGE_AF)
PGP000591 |
Wang X et al. Circ Genom Precis Med (2023)
CHARGE-AF predicted 5-year risk of atrial fibrillation atrial fibrillation 1,117,400
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004613/ScoringFiles/PGS004613.txt.gz
PGS003133
(ExPRSweb_Thinness_STILTS-UKHLS_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Thinness body mass index 1,117,469
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003133/ScoringFiles/PGS003133.txt.gz
PGS004887
(T2D_gePGS)
PGP000619 |
Mandla R et al. Genome Med (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,117,628
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004887/ScoringFiles/PGS004887.txt.gz
PGS002863
(ExPRSweb_CRP_28887542-GCST004941_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
C-reactive protein C-reactive protein measurement 1,118,117
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002863/ScoringFiles/PGS002863.txt.gz
PGS003228
(ExPRSweb_eGFR_20171017-MW-eGFR-EA_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate glomerular filtration rate 1,118,118
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003228/ScoringFiles/PGS003228.txt.gz
PGS003108
(ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 1,118,480
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003108/ScoringFiles/PGS003108.txt.gz
PGS000354
(PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Any cancer cancer 1,118,667
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000354/ScoringFiles/PGS000354.txt.gz
PGS003972
(PRSAAA)
PGP000513 |
Roychowdhury T et al. Nat Genet (2023)
Abdominal aortic aneurysm Abdominal Aortic Aneurysm 1,118,997
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003972/ScoringFiles/PGS003972.txt.gz
PGS003973
(PRSAAA_woUKB)
PGP000513 |
Roychowdhury T et al. Nat Genet (2023)
Abdominal aortic aneurysm Abdominal Aortic Aneurysm 1,118,997
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003973/ScoringFiles/PGS003973.txt.gz
PGS002239
(DBP_PRS)
PGP000270 |
Breeyear JH et al. Circ Genom Precis Med (2022)
Diastolic blood pressure diastolic blood pressure 1,119,054
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002239/ScoringFiles/PGS002239.txt.gz
PGS002883
(ExPRSweb_CRP_28887542-GCST004941_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
C-reactive protein C-reactive protein measurement 1,119,064
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002883/ScoringFiles/PGS002883.txt.gz
PGS000491
(PRSWEB_PHECODE174.1_Onco-iCOGS-ER-negative-BRCA_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 1,119,140
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000491/ScoringFiles/PGS000491.txt.gz
PGS000499
(PRSWEB_PHECODE174.1_Onco-iCOGS-ER-positive-BRCA_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 1,119,140
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000499/ScoringFiles/PGS000499.txt.gz
PGS000507
(PRSWEB_PHECODE174.1_Onco-iCOGS-Overall-BRCA_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 1,119,140
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000507/ScoringFiles/PGS000507.txt.gz
PGS000892
(GLGC_2021_EUR_LDL_PRS_weights_PRS-CS)
PGP000230 |
Graham SE et al. Nature (2021)
LDL cholesterol low density lipoprotein cholesterol measurement 1,119,211
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000892/ScoringFiles/PGS000892.txt.gz
PGS000590
(PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Prostate cancer prostate carcinoma 1,119,236
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000590/ScoringFiles/PGS000590.txt.gz