Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004097
(prscs.CV.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 1,073,268
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004097/ScoringFiles/PGS004097.txt.gz
PGS003362
(GSCAN_AgeSmk_2022_PRS_WEIGHTS_AMR)
 PGP000410 |
Saunders GRB et al. Nature (2022)
 Age of smoking initiation age at initiation of smoking 1,073,689
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003362/ScoringFiles/PGS003362.txt.gz
PGS004951
(DCM_MTAG_exclAUMC)
 PGP000672 |
Jurgens SJ et al. Nat Genet (2024)
 Dilated cardiomyopathy (MTAG) dilated cardiomyopathy 1,075,760
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004951/ScoringFiles/PGS004951.txt.gz
PGS004751
(current_smoker_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Current smoker smoking status measurement 1,076,735
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004751/ScoringFiles/PGS004751.txt.gz
PGS004687
(bladder_cancer)
 PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
 Bladder cancer urinary bladder carcinoma 1,077,775
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004687/ScoringFiles/PGS004687.txt.gz
PGS004689
(colorectal_cancer)
 PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
 Colorectal cancer colorectal carcinoma 1,077,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004689/ScoringFiles/PGS004689.txt.gz
PGS002765
(SBP_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Hypertension hypertension 1,077,894
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002765/ScoringFiles/PGS002765.txt.gz
PGS000383
(PRSWEB_PHECODE153.3_C19_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of rectum, rectosigmoid junction, and anus rectum cancer,
rectosigmoid junction neoplasm		 1,078,799
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000383/ScoringFiles/PGS000383.txt.gz
PGS000335
(BC_PRSCS)
 PGP000102 |
Mars N et al. Nat Commun (2020)
 Breast cancer breast carcinoma 1,079,089
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000335/ScoringFiles/PGS000335.txt.gz
PGS000363
(PRSWEB_PHECODE150_C15_PRS-CS_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Esophageal cancer esophageal cancer 1,081,646
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000363/ScoringFiles/PGS000363.txt.gz
PGS003425
(prscs_hemoglobin)
 PGP000432 |
Toivonen J et al. Vox Sanguinis (2023)
 Hemoglobin hemoglobin measurement 1,082,250
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003425/ScoringFiles/PGS003425.txt.gz
PGS004614
(DivD_SNPWeights)
 PGP000592 |
Wu Y et al. Cell Genom (2023)
 Diverticular disease diverticular disease 1,082,282
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004614/ScoringFiles/PGS004614.txt.gz
PGS003426
(prscs_ferritin)
 PGP000432 |
Toivonen J et al. Vox Sanguinis (2023)
 Ferritin ferritin measurement 1,082,414
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003426/ScoringFiles/PGS003426.txt.gz
PGS002761
(Glaucoma_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Glaucoma glaucoma 1,082,518
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002761/ScoringFiles/PGS002761.txt.gz
PGS004825
(RDW_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Red cell distribution width Red cell distribution width 1,082,665
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004825/ScoringFiles/PGS004825.txt.gz
PGS000202
(PROB_ALC_FT12)
 PGP000084 |
Barr PB et al. Transl Psychiatry (2020)
 Problematic alcohol use alcohol dependence measurement 1,083,002
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000202/ScoringFiles/PGS000202.txt.gz
PGS002769
(Rheumatoid_arthritis_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Seropositive rheumatoid arthritis rheumatoid arthritis 1,083,565
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002769/ScoringFiles/PGS002769.txt.gz
PGS002807
(PRSCS_SBP)
 PGP000384 |
Parcha V et al. Circ Genom Precis Med (2022)
 Systolic blood pressure systolic blood pressure 1,084,157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002807/ScoringFiles/PGS002807.txt.gz
PGS005274
(tc_vs_bng_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Thyroid carcenoma vs benign nodular goiter benign,
thyroid carcinoma,
nodular goiter		 1,084,965
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005274/ScoringFiles/PGS005274.txt.gz
PGS005272
(lymphocytic_thyroiditis_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Lymphocytic thyroiditis Hashimoto's thyroiditis 1,085,142
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005272/ScoringFiles/PGS005272.txt.gz
PGS005271
(lymphocytic_thyroiditis_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Lymphocytic thyroiditis Hashimoto's thyroiditis 1,085,156
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005271/ScoringFiles/PGS005271.txt.gz
PGS005273
(tc_vs_bng_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Thyroid carcenoma vs benign nodular goiter benign,
thyroid carcinoma,
nodular goiter		 1,085,164
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005273/ScoringFiles/PGS005273.txt.gz
PGS005260
(thyroid_cancer_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Thyroid carcenoma thyroid carcinoma 1,085,170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005260/ScoringFiles/PGS005260.txt.gz
PGS005263
(benign_nodular_goiter_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Benign nodular goiter benign,
nodular goiter		 1,085,170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005263/ScoringFiles/PGS005263.txt.gz
PGS005266
(graves_disease_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Graves' disease Graves disease 1,085,170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005266/ScoringFiles/PGS005266.txt.gz
PGS005269
(hypothyroidism_eur_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Hypothyroidism hypothyroidism 1,085,170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005269/ScoringFiles/PGS005269.txt.gz
PGS005259
(thyroid_cancer_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Thyroid carcenoma thyroid carcinoma 1,085,173
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005259/ScoringFiles/PGS005259.txt.gz
PGS005262
(benign_nodular_goiter_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Benign nodular goiter benign,
nodular goiter		 1,085,173
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005262/ScoringFiles/PGS005262.txt.gz
PGS005265
(graves_disease_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Graves' disease Graves disease 1,085,173
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005265/ScoringFiles/PGS005265.txt.gz
PGS005268
(hypothyroidism_mixed_prscs)
 PGP000748 |
White SL et al. medRxiv (2025)
|Pre		 Hypothyroidism hypothyroidism 1,085,173
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005268/ScoringFiles/PGS005268.txt.gz
PGS004761
(Eosinophils_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Eosinophil count eosinophil count 1,086,541
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004761/ScoringFiles/PGS004761.txt.gz
PGS003586
(PE)
 PGP000462 |
Honigberg MC et al. Nat Med (2023)
 Pre-eclampsia preeclampsia 1,087,033
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003586/ScoringFiles/PGS003586.txt.gz
PGS002758
(Colorectal_cancer_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Colorectal cancer colorectal cancer 1,087,843
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002758/ScoringFiles/PGS002758.txt.gz
PGS003587
(GH)
 PGP000462 |
Honigberg MC et al. Nat Med (2023)
 Gestational hypertension preeclampsia 1,087,916
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003587/ScoringFiles/PGS003587.txt.gz
PGS004095
(prscs.auto.GCST90018959.Height)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Height body height 1,088,125
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004095/ScoringFiles/PGS004095.txt.gz
PGS003979
(CRC_PRSCS)
 PGP000515 |
Tamlander M et al. Br J Cancer (2023)
 Colorectal cancer colorectal carcinoma 1,088,133
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003979/ScoringFiles/PGS003979.txt.gz
PGS004579
(BRCA_PRSCS)
 PGP000562 |
Youssef O et al. Lab Invest (2024)
 Breast cancer breast carcinoma 1,088,163
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004579/ScoringFiles/PGS004579.txt.gz
PGS003333
(MDD-PRS)
 PGP000399 |
Fang Y et al. Biol Psychiatry (2022)
 Major Depressive Disorder major depressive disorder 1,088,415
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003333/ScoringFiles/PGS003333.txt.gz
PGS002770
(Stroke_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Stroke stroke 1,088,719
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002770/ScoringFiles/PGS002770.txt.gz
PGS002752
(Drinks_per_week_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Alcohol consumption (drinks per week) alcohol consumption quality 1,089,551
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002752/ScoringFiles/PGS002752.txt.gz
PGS004621
(cirrhosis_pgs_eur)
 PGP000594 |
Ghouse J et al. Nat Genet (2024)
 Cirrhosis cirrhosis of liver 1,089,806
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004621/ScoringFiles/PGS004621.txt.gz
PGS001780
(CHD_PRSCS)
 PGP000261 |
Tamlander M et al. Commun Biol (2022)
 Coronary heart disease coronary artery disease 1,090,048
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001780/ScoringFiles/PGS001780.txt.gz
PGS004926
(Back_3000)
 PGP000661 |
Tsepilov YA et al. J Pers Med (2023)
 Chronic back pain Back pain 1,090,574
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004926/ScoringFiles/PGS004926.txt.gz
PGS002755
(Atopic_dermatitis_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Atopic dermatitis atopic eczema 1,090,702
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002755/ScoringFiles/PGS002755.txt.gz
PGS002757
(eGFR_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Chronic kidney disease chronic kidney disease 1,090,783
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002757/ScoringFiles/PGS002757.txt.gz
PGS002764
(LDL_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Hypercholesterolemia Hypercholesterolemia 1,091,280
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002764/ScoringFiles/PGS002764.txt.gz
PGS005203
(G23_BMI_2025_PRSCSx_LC_EUR)
 PGP000724 |
Smit RAJ et al. Nat Med (2025)
 Body mass index (BMI) body mass index 1,091,375
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005203/ScoringFiles/PGS005203.txt.gz - Check Terms/Licenses
PGS002756
(Atrial_fibrillation_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Atrial fibrillation atrial fibrillation 1,091,491
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002756/ScoringFiles/PGS002756.txt.gz
PGS002768
(BMD_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Osteoporosis osteoporosis,
heel bone mineral density		 1,091,549
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002768/ScoringFiles/PGS002768.txt.gz
PGS002771
(Type_2_diabetes_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,091,608
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002771/ScoringFiles/PGS002771.txt.gz
Showing 4401 to 4450 of 5296 rows