Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000790
(CC_Melanoma_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Melanoma melanoma 24
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000790/ScoringFiles/PGS000790.txt.gz
PGS001299
(GBE_cancer1041)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Cervical cancer cervical carcinoma 24
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001299/ScoringFiles/PGS001299.txt.gz
PGS002729
(PRS_knee)
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Knee osteoarthritis osteoarthritis, knee 24
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002729/ScoringFiles/PGS002729.txt.gz
PGS002736
(PRS24)
 PGP000344 |
Bafligil C et al. Genet Med (2022)
 Endometrial cancer endometrial carcinoma 24
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002736/ScoringFiles/PGS002736.txt.gz
PGS003020
(ExPRSweb_Hypertension_finngen-R4-FG_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertension 24
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003020/ScoringFiles/PGS003020.txt.gz
PGS003021
(ExPRSweb_Hypertension_finngen-R4-FG_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Hypertension hypertension 24
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003021/ScoringFiles/PGS003021.txt.gz
PGS003450
(PRS24_MM)
 PGP000448 |
Berndt SI et al. Leukemia (2022)
 Multiple myeloma multiple myeloma 24
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003450/ScoringFiles/PGS003450.txt.gz
PGS005106
(PRSAFR_ER−)
 PGP000694 |
Jia G et al. Nat Genet (2024)
 ER-negative breast cancer estrogen-receptor negative breast cancer 24
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005106/ScoringFiles/PGS005106.txt.gz
PGS000484
(PRSWEB_PHECODE174.1_D05_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 25
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000484/ScoringFiles/PGS000484.txt.gz
PGS001281
(GBE_HC86)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Migraine migraine disorder 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001281/ScoringFiles/PGS001281.txt.gz
PGS001773
(PRS_atopicDermatitis)
 PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
 Moderate-to-severe atopic dermatitis atopic eczema 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001773/ScoringFiles/PGS001773.txt.gz
PGS002827
(ExPRSweb_Alcohol_20403_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Alcohol consumption alcohol consumption quality 25
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002827/ScoringFiles/PGS002827.txt.gz
PGS003413
(rvPRS_IOP)
 PGP000426 |
Gao XR et al. Nat Commun (2022)
 Intraocular pressure intraocular pressure measurement 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003413/ScoringFiles/PGS003413.txt.gz
PGS003487
(PRS_IL4)
 PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
 General atopic disease (IL-4 related variants) allergic disease 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003487/ScoringFiles/PGS003487.txt.gz
PGS003652
(R_hippocampal_tail_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal tail volume hippocampal formation volume 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003652/ScoringFiles/PGS003652.txt.gz
PGS003796
(LDL_SAS_CT)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 LDL cholesterol low density lipoprotein cholesterol measurement 25
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003796/ScoringFiles/PGS003796.txt.gz
PGS004249
(PRS25_ovary)
 PGP000542 |
Kim ES et al. NPJ Precis Oncol (2023)
 Ovarian cancer ovarian carcinoma 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004249/ScoringFiles/PGS004249.txt.gz
PGS004890
(CC-GWAS_PRS)
 PGP000620 |
Sun X et al. Cancer Res (2024)
 Triple negative breast cancer versus luminal breast cancer triple-negative breast cancer 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004890/ScoringFiles/PGS004890.txt.gz
PGS004891
(TNBC_PRS25)
 PGP000620 |
Sun X et al. Cancer Res (2024)
 Triple negative breast cancer triple-negative breast cancer 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004891/ScoringFiles/PGS004891.txt.gz
PGS005169
(PRS25_LUAD)
 PGP000713 |
Blechter B et al. JAMA Netw Open (2023)
 Lung adenocarcinoma lung adenocarcinoma 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005169/ScoringFiles/PGS005169.txt.gz
PGS000114
(GRS-JIA-20)
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Juvenile Idiopathic Arthritis juvenile idiopathic arthritis 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000114/ScoringFiles/PGS000114.txt.gz
PGS000736
(PRS_QRS)
 PGP000144 |
Tadros R et al. Eur Heart J (2019)
 QRS duration QRS duration 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000736/ScoringFiles/PGS000736.txt.gz
PGS000945
(GBE_HC710)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Dementia in Alzheimer's disease (time-to-event) dementia,
Alzheimer disease		 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000945/ScoringFiles/PGS000945.txt.gz
PGS001371
(GBE_INI2976)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Age diabetes diagnosed diabetes mellitus,
age at diagnosis		 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001371/ScoringFiles/PGS001371.txt.gz
PGS001413
(GBE_INI22423)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 LV stroke volume left ventricular stroke volume measurement 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001413/ScoringFiles/PGS001413.txt.gz
PGS003737
(PRS26_BrC)
 PGP000470 |
Xin J et al. EBioMedicine (2023)
 Brain cancer brain neoplasm 26
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003737/ScoringFiles/PGS003737.txt.gz
PGS004954
(PRS26_TC)
 PGP000676 |
Pozdeyev N et al. J Clin Endocrinol Metab (2024)
 Thyroid cancer thyroid carcinoma 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004954/ScoringFiles/PGS004954.txt.gz
PGS000010
(GRS27)
 PGP000003 |
Mega JL et al. Lancet (2015)
 Coronary heart disease coronary artery disease 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000010/ScoringFiles/PGS000010.txt.gz
PGS000146
(CRC_GRS_27)
 PGP000069 |
Hsu L et al. Gastroenterology (2015)
 Colorectal cancer colorectal cancer 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000146/ScoringFiles/PGS000146.txt.gz
PGS000372
(PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colorectal cancer colorectal cancer 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000372/ScoringFiles/PGS000372.txt.gz
PGS000424
(PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Melanomas of skin (diagnosis or history) melanoma 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000424/ScoringFiles/PGS000424.txt.gz
PGS000454
(PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000454/ScoringFiles/PGS000454.txt.gz
PGS000649
(PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Chronic lymphocytic leukemia chronic lymphocytic leukemia 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000649/ScoringFiles/PGS000649.txt.gz
PGS000652
(PRSWEB_PHECODE204.4_C90_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Multiple myeloma multiple myeloma 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000652/ScoringFiles/PGS000652.txt.gz
PGS000739
(HCM_GRS)
 PGP000146 |
Harper AR et al. Nat Genet (2021)
 Hypertrophic cardiomyopathy hypertrophic cardiomyopathy 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000739/ScoringFiles/PGS000739.txt.gz
PGS000854
(T2D_BetaCell)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with beta cell function) type 2 diabetes mellitus 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000854/ScoringFiles/PGS000854.txt.gz
PGS002233
(PRS27_NMR)
 PGP000266 |
Chen LS et al. Pharmacogenomics (2018)
 Nicotine metabolite ratio nicotine metabolite ratio 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002233/ScoringFiles/PGS002233.txt.gz
PGS003334
(PRS_dementia)
 PGP000402 |
Chen Y et al. Arch Gerontol Geriatr (2022)
 Dementia dementia 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003334/ScoringFiles/PGS003334.txt.gz
PGS004321
(PRS27_CAD)
 PGP000554 |
Marston NA et al. Circulation (2019)
 Coronary heart disease coronary artery disease 27
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004321/ScoringFiles/PGS004321.txt.gz
PGS000200
(GRS28)
 PGP000082 |
Tikkanen E et al. Arterioscler Thromb Vasc Biol (2013)
 Coronary heart disease coronary artery disease 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000200/ScoringFiles/PGS000200.txt.gz
PGS000340
(LDL-Cpsp)
 PGP000107 |
Trinder M et al. Circ Genom Precis Med (2020)
 LDL cholesterol low density lipoprotein cholesterol measurement 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000340/ScoringFiles/PGS000340.txt.gz
PGS000452
(PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000452/ScoringFiles/PGS000452.txt.gz
PGS000453
(PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000453/ScoringFiles/PGS000453.txt.gz
PGS000455
(PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Basal cell carcinoma basal cell carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000455/ScoringFiles/PGS000455.txt.gz
PGS000666
(PGS_LVESVi)
 PGP000126 |
Pirruccello JP et al. Nat Commun (2020)
 Body surface area-indexed left ventricular end-systolic volume left ventricular systolic function measurement 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000666/ScoringFiles/PGS000666.txt.gz
PGS002302
(PRS28_glioma)
 PGP000328 |
Choi J et al. Int J Cancer (2020)
 Glioma glioma 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002302/ScoringFiles/PGS002302.txt.gz
PGS003403
(PRS28_LDL)
 PGP000420 |
Trinder M et al. J Am Coll Cardiol (2019)
 LDL cholesterol low density lipoprotein cholesterol measurement 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003403/ScoringFiles/PGS003403.txt.gz
PGS003412
(PRS28_melanoma)
 PGP000424 |
Olsen CM et al. Br J Dermatol (2019)
 Melanoma melanoma 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003412/ScoringFiles/PGS003412.txt.gz
PGS003441
(GRS28_AD)
 PGP000444 |
Petrican R et al. Sci Rep (2023)
 Alzheimer's disease Alzheimer disease 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003441/ScoringFiles/PGS003441.txt.gz
PGS003741
(PRS28_OC)
 PGP000470 |
Xin J et al. EBioMedicine (2023)
 Ovarian cancer ovarian carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003741/ScoringFiles/PGS003741.txt.gz
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