Publications

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000269 1 1 Khan A Genome-wide polygenic score to predict chronic kidney disease across ancestries. Nat Med 16/06/2022 10.1038/s41591-022-01869-1 35710995
PGP000006 5 5 Khera AV Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. Nat Genet 13/08/2018 10.1038/s41588-018-0183-z 30104762
PGP000360 0 1 Kukkle PL Genome-Wide Polygenic Score Predicts Large Number of High Risk Individuals in Monogenic Undiagnosed Young Onset Parkinson's Disease Patients from India. Adv Biol (Weinh) 10/07/2022 10.1002/adbi.202101326 35810474
PGP000108 0 1 Hindy G Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease. Arterioscler Thromb Vasc Biol 22/09/2020 10.1161/atvbaha.120.314856 32957805
PGP000515 1 1 Tamlander M Genome-wide polygenic risk scores for colorectal cancer have implications for risk-based screening Br J Cancer 13/11/2023 10.1038/s41416-023-02536-z 38172535
PGP000203 1 1 Forrest IS Genome-wide polygenic risk score for retinopathy of type 2 diabetes. Hum Mol Genet 01/05/2021 10.1093/hmg/ddab067 33704450
PGP000294 2 2 Thomas M Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk. Am J Hum Genet 05/08/2020 10.1016/j.ajhg.2020.07.006 32758450
PGP000398 1 1 Ghouse J Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism. Nat Genet 19/01/2023 10.1038/s41588-022-01286-7 36658437
PGP000080 1 1 Coleman JRI Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank. Mol Psychiatry 23/01/2020 10.1038/s41380-019-0546-6 31969693
PGP000327 1 1 Coassin S Genome-Wide Characterization of a Highly Penetrant Form of Hyperlipoprotein(a)emia Associated With Genetically Elevated Cardiovascular Risk. Circ Genom Precis Med 08/02/2022 10.1161/circgen.121.003489 35133173
PGP000465 2 2 Hatoum AS Genome-wide Association Study Shows That Executive Functioning Is Influenced by GABAergic Processes and Is a Neurocognitive Genetic Correlate of Psychiatric Disorders. Biol Psychiatry 14/07/2022 10.1016/j.biopsych.2022.06.034 36150907
PGP000301 1 1 Roselli C Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse. Eur Heart J 04/03/2022 10.1093/eurheartj/ehac049 35245370
PGP000672 6 6 Jurgens SJ Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience. Nat Genet 21/11/2024 10.1038/s41588-024-01975-5 39572784
PGP000431 5 5 Ko CL Genome-wide association study reveals ethnicity-specific SNPs associated with ankylosing spondylitis in the Taiwanese population. J Transl Med 12/12/2022 10.1186/s12967-022-03701-3 36510243
PGP000427 1 1 Krohn L Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects. Nat Commun 05/12/2022 10.1038/s41467-022-34732-5 36470867
PGP000692 4 4 Hoffmann TJ Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves prediction across ancestry groups. Nat Genet 10/02/2025 10.1038/s41588-024-02068-z 39930085
PGP000496 2 2 Sofer T Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sex. EBioMedicine 28/03/2023 10.1016/j.ebiom.2023.104536 36989840
PGP000061 1 1 MacGregor S Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. Nat Genet 27/07/2018 10.1038/s41588-018-0176-y 30054594
PGP000796 1 1 Koutros S Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights. Eur Urol 19/05/2023 10.1016/j.eururo.2023.04.020 37210288
PGP000680 4 4 Barnes DR Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer. NPJ Genom Med 20/11/2025 10.1038/s41525-025-00529-w 41266372
PGP000088 5 7 Zhang H Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nat Genet 18/05/2020 10.1038/s41588-020-0609-2 32424353
PGP000228 1 1 Revez JA Genome-wide association study identifies 143 loci associated with 25 hydroxyvitamin D concentration. Nat Commun 02/04/2020 10.1038/s41467-020-15421-7 32242144
PGP000180 1 1 Innes H Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1. Gastroenterology 16/06/2020 10.1053/j.gastro.2020.06.014 32561361
PGP000777 1 1 Aliyu U Genome-wide association study and polygenic score assessment of insulin resistance. Front Endocrinol (Lausanne) 13/06/2024 10.3389/fendo.2024.1384103 38938516
PGP000733 1 1 Rand SA Genome-wide association study and polygenic risk prediction of hypothyroidism. Nat Genet 14/11/2025 10.1038/s41588-025-02410-z 41238958
PGP000513 2 2 Roychowdhury T Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target. Nat Genet 16/10/2023 10.1038/s41588-023-01510-y 37845353
PGP000206 1 1 Teumer A Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nat Commun 11/09/2019 10.1038/s41467-019-11576-0 31511532
PGP000608 2 2 Zheng SL Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy. Nat Genet 21/11/2024 10.1038/s41588-024-01952-y 39572783
PGP000030 1 1 Klarin D Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. Nat Genet 01/11/2019 10.1038/s41588-019-0519-3 31676865
PGP000511 1 1 Rasooly D Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure. Nat Commun 10/07/2023 10.1038/s41467-023-39253-3 37429843
PGP000694 3 6 Jia G Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction. Nat Genet 13/05/2024 10.1038/s41588-024-01736-4 38741014
PGP000260 1 1 Barc J Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility. Nat Genet 24/02/2022 10.1038/s41588-021-01007-6 35210625
PGP000582 2 2 Gorman BR Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries. Nat Genet 02/12/2024 10.1038/s41588-024-01764-0 39623103
PGP000499 1 1 Zhang Z Genome-wide association analyses identified novel susceptibility loci for pulmonary embolism among Han Chinese population. BMC Med 19/04/2023 10.1186/s12916-023-02844-4 37076872
PGP000211 33 34 Aly DM Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes Nat Genet 04/11/2021 10.1038/s41588-021-00948-2 34737425
PGP000178 2 2 Chen L Genome-wide assessment of genetic risk for systemic lupus erythematosus and disease severity. Hum Mol Genet 01/06/2020 10.1093/hmg/ddaa030 32077931
PGP000302 2 2 Horowitz JE Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease. Nat Genet 03/03/2022 10.1038/s41588-021-01006-7 35241825
PGP000757 1 1 Enzan N Genome-wide analysis of heart failure yields insights into disease heterogeneity and enables prognostic prediction in the Japanese population. Nat Commun 03/11/2025 10.1038/s41467-025-64659-6 41184235
PGP000581 3 3 Keaton JM Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits. Nat Genet 30/04/2024 10.1038/s41588-024-01714-w 38689001
PGP000723 26 26 Xiang R Genome-wide analyses of variance in blood cell phenotypes provide new insights into complex trait biology and prediction. Nat Commun 07/05/2025 10.1038/s41467-025-59525-4 40335489
PGP000164 3 3 Khan Z Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade. Nat Commun 07/06/2021 10.1038/s41467-021-23661-4 34099659
PGP000649 1 1 Lawingco T Genetic variants in glutamate-, Aβ-, and tau-related pathways determine polygenic risk for Alzheimer's disease. Neurobiol Aging 12/11/2020 10.1016/j.neurobiolaging.2020.11.009 33303219
PGP000303 2 2 Groenland EH Genetic variants associated with low-density lipoprotein cholesterol and systolic blood pressure and the risk of recurrent cardiovascular disease in patients with established vascular disease. Atherosclerosis 11/03/2022 10.1016/j.atherosclerosis.2022.03.006 35317921
PGP000043 1 1 Morieri ML Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial. Diabetes Care 27/09/2018 10.2337/dc18-0709 30262460
PGP000591 2 2 Wang X Genetic Susceptibility to Atrial Fibrillation Identified via Deep Learning of 12-Lead Electrocardiograms. Circ Genom Precis Med 06/06/2023 10.1161/circgen.122.003808 37278238
PGP000737 0 5 Qafoud F Genetic Susceptibility to Arrhythmia Phenotypes in a Middle Eastern Cohort of 14,259 Whole-Genome Sequenced Individuals. J Clin Med 15/02/2024 10.3390/jcm13041102 38398418
PGP000736 1 1 Ma Y Genetic Susceptibility Modifies Relationships Between Air Pollutants and Stroke Risk: A Large Cohort Study. Stroke 22/12/2023 10.1161/strokeaha.123.044284 38134266
PGP000570 1 1 Li D Genetic susceptibility and lifestyle modify the association of long-term air pollution exposure on major depressive disorder: a prospective study in UK Biobank. BMC Med 21/02/2023 10.1186/s12916-023-02783-0 36810050
PGP000062 1 1 Qi Q Genetics of Type 2 Diabetes in U.S. Hispanic/Latino Individuals: Results From the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Diabetes 02/03/2017 10.2337/db16-1150 28254843
PGP000128 46 46 Sinnott-Armstrong N Genetics of 35 blood and urine biomarkers in the UK Biobank. Nat Genet 18/01/2021 10.1038/s41588-020-00757-z 33462484
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