Publications

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000491 1 0 Fernandez-Rozadilla C Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries. Nat Genet 20/12/2022 10.1038/s41588-022-01222-9 36539618
PGP000170 1 0 Huyghe JR Discovery of common and rare genetic risk variants for colorectal cancer. Nat Genet 03/12/2018 10.1038/s41588-018-0286-6 30510241
PGP000088 5 7 Zhang H Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nat Genet 18/05/2020 10.1038/s41588-020-0609-2 32424353
PGP000691 1 1 Lee DSM Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum. Nat Genet 07/04/2025 10.1038/s41588-025-02140-2 40195560
PGP000122 1 1 Conti DV Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet 04/01/2021 10.1038/s41588-020-00748-0 33398198
PGP000745 1 1 Small AM Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction. Nat Genet 19/12/2025 10.1038/s41588-025-02417-6 41419686
PGP000500 4 4 Shrine N Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk. Nat Genet 13/03/2023 10.1038/s41588-023-01314-0 36914875
PGP000019 1 1 Schumacher FR Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet 11/06/2018 10.1038/s41588-018-0142-8 29892016
PGP000774 10 10 Li JL Improved polygenic risk prediction models for breast cancer subtypes in women of African ancestry. Nat Genet 02/02/2026 10.1038/s41588-026-02501-5 41629673
PGP000694 3 6 Jia G Genome-wide association analyses of breast cancer in women of African ancestry identify new susceptibility loci and improve risk prediction. Nat Genet 13/05/2024 10.1038/s41588-024-01736-4 38741014
PGP000068 8 8 Cai N Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Nat Genet 30/03/2020 10.1038/s41588-020-0594-5 32231276
PGP000390 1 1 Wuttke M A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet 31/05/2019 10.1038/s41588-019-0407-x 31152163
PGP000668 3 3 China Kadoorie Biobank Collaborative Group. Joint impact of polygenic risk score and lifestyles on early- and late-onset cardiovascular diseases. Nat Hum Behav 10/07/2024 10.1038/s41562-024-01923-7 38987358
PGP000724 7 7 Smit RAJ Polygenic prediction of body mass index and obesity through the life course and across ancestries. Nat Med 21/07/2025 10.1038/s41591-025-03827-z 40691366
PGP000313 4 4 Kamiza AB Transferability of genetic risk scores in African populations. Nat Med 02/06/2022 10.1038/s41591-022-01835-x 35654908
PGP000269 1 1 Khan A Genome-wide polygenic score to predict chronic kidney disease across ancestries. Nat Med 16/06/2022 10.1038/s41591-022-01869-1 35710995
PGP000466 3 3 Patel AP A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease. Nat Med 06/07/2023 10.1038/s41591-023-02429-x 37414900
PGP000412 2 2 Kachuri L Genetically adjusted PSA levels for prostate cancer screening. Nat Med 01/06/2023 10.1038/s41591-023-02277-9 37264206
PGP000381 0 6 Hao L Development of a clinical polygenic risk score assay and reporting workflow. Nat Med 18/04/2022 10.1038/s41591-022-01767-6 35437332
PGP000091 0 1 Ferrat LA A combined risk score enhances prediction of type 1 diabetes among susceptible children. Nat Med 07/08/2020 10.1038/s41591-020-0930-4 32770166
PGP000446 1 3 Tcheandjieu C Large-scale genome-wide association study of coronary artery disease in genetically diverse populations. Nat Med 01/08/2022 10.1038/s41591-022-01891-3 35915156
PGP000100 5 5 Mars N Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers. Nat Med 07/04/2020 10.1038/s41591-020-0800-0 32273609
PGP000462 3 3 Honigberg MC Polygenic prediction of preeclampsia and gestational hypertension. Nat Med 29/05/2023 10.1038/s41591-023-02374-9 37248299
PGP000363 1 2 Sapkota Y Genetic risk score enhances the risk prediction of severe obesity in adult survivors of childhood cancer. Nat Med 25/07/2022 10.1038/s41591-022-01902-3 35879615
PGP000729 4 5 Gibson TM Polygenic risk scores, radiation treatment exposures and subsequent cancer risk in childhood cancer survivors. Nat Med 07/03/2024 10.1038/s41591-024-02837-7 38454124
PGP000768 1 1 Marston NA Endothelial cell-related genetic variants identify LDL cholesterol-sensitive individuals who derive greater benefit from aggressive lipid lowering. Nat Med 26/02/2025 10.1038/s41591-025-03533-w 40011692
PGP000490 1 1 Hatoum AS Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders. Nat Ment Health 22/03/2023 10.1038/s44220-023-00034-y 37250466
PGP000089 79 79 Folkersen L Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals. Nat Metab 16/10/2020 10.1038/s42255-020-00287-2 33067605
PGP000137 3 4 Ritchie SC Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases Nat Metab 08/11/2021 10.1038/s42255-021-00478-5 34750571
PGP000333 2 3 Mishra A Stroke genetics informs drug discovery and risk prediction across ancestries Nature 30/09/2022 10.1038/s41586-022-05165-3 36180795
PGP000410 20 20 Saunders GRB Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature 07/12/2022 10.1038/s41586-022-05477-4 36477530
PGP000230 12 12 Graham SE The power of genetic diversity in genome-wide association studies of lipids. Nature 09/12/2021 https://doi.org/10.1038/s41586-021-04064-3 34887591
PGP000382 6 6 Yengo L A saturated map of common genetic variants associated with human height. Nature 12/10/2022 10.1038/s41586-022-05275-y 36224396
PGP000501 26 26 Shim I Clinical utility of polygenic scores for cardiometabolic disease in Arabs. Nature Communications 18/10/2023 10.1038/s41467-023-41985-1 37852978
PGP000516 0 1 Soh P X.Y. Prostate cancer genetic risk and associated aggressive disease in men of African ancestry Nature Communications 16/11/2023 10.1038/s41467-023-43726-w 38052806
PGP000488 2 2 Wang A W Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants Nature Genetics 21/08/2023 10.1038/s41588-023-01534-4 37945903
PGP000076 0 1 Khera AV Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. N Engl J Med 13/11/2016 10.1056/NEJMoa1605086 27959714
PGP000730 0 1 McHugh JK Assessment of a Polygenic Risk Score in Screening for Prostate Cancer. N Engl J Med 01/04/2025 10.1056/nejmoa2407934 40214032
PGP000079 1 1 Kathiresan S Polymorphisms associated with cholesterol and risk of cardiovascular events. N Engl J Med 01/03/2008 10.1056/nejmoa0706728 18354102
PGP000649 1 1 Lawingco T Genetic variants in glutamate-, Aβ-, and tau-related pathways determine polygenic risk for Alzheimer's disease. Neurobiol Aging 12/11/2020 10.1016/j.neurobiolaging.2020.11.009 33303219
PGP000529 2 2 Acosta JN Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors. Neurology 23/01/2023 10.1212/wnl.0000000000206763 36690452
PGP000369 0 1 Jaworek T Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke. Neurology 31/08/2022 10.1212/wnl.0000000000201006 36240095
PGP000339 1 1 Xicota L Association of APOE-Independent Alzheimer Disease Polygenic Risk Score With Brain Amyloid Deposition in Asymptomatic Older Adults. Neurology 23/05/2022 10.1212/wnl.0000000000200544 35606148
PGP000285 1 1 Lu X Development and Validation of a Polygenic Risk Score for Stroke in the Chinese Population. Neurology 24/05/2021 10.1212/wnl.0000000000012263 34031205
PGP000039 2 2 Tosto G Polygenic risk scores in familial Alzheimer disease. Neurology 17/02/2017 10.1212/WNL.0000000000003734 28213371
PGP000454 1 1 Yang L Association of accelerometer-derived circadian abnormalities and genetic risk with incidence of atrial fibrillation. NPJ Digit Med 04/03/2023 10.1038/s41746-023-00781-3 36869222
PGP000759 20 20 Jordà P Genetic analyses across cardiovascular traits: leveraging genetic correlations to empower locus discovery and prediction in common cardiovascular diseases. NPJ Genom Med 29/09/2025 10.1038/s41525-025-00515-2 41022758
PGP000680 4 4 Barnes DR Genome-wide association study of 398,238 women unveils seven loci associated with high-grade serous ovarian cancer. NPJ Genom Med 20/11/2025 10.1038/s41525-025-00529-w 41266372
PGP000458 0 1 Pavelka L Age at onset as stratifier in idiopathic Parkinson's disease - effect of ageing and polygenic risk score on clinical phenotypes. NPJ Parkinsons Dis 09/08/2022 10.1038/s41531-022-00342-7 35945230
PGP000590 1 1 Shieh Y Development and testing of a polygenic risk score for breast cancer aggressiveness. NPJ Precis Oncol 15/05/2023 10.1038/s41698-023-00382-z 37188791
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