Trait: emotional symptom measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007803
Description quantification of some aspect of emotional problem symptoms, such as their existence and severity, usually via a standardised questionnaire such as the emotional symptoms subscale of the Strengths and Difficulties Questionnaire or interview with a qualified mental health professional
Trait category
Other measurement
Child trait(s) 5 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "emotional symptom measurement" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS001016
(GBE_BIN1950)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Sensitivity / hurt feelings feeling emotionally hurt measurement 7,922
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001016/ScoringFiles/PGS001016.txt.gz
PGS001017
(GBE_BIN2010)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Suffer from 'nerves' feeling nervous measurement 3,348
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001017/ScoringFiles/PGS001017.txt.gz
PGS001018
(GBE_BIN_FC10006160)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Attending social / leisure activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) social interaction measurement 2,912
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001018/ScoringFiles/PGS001018.txt.gz
PGS001019
(GBE_BIN_FC20006160)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Attending social / leisure activities (regular attendance at a gym or sports club) social interaction measurement 11,361
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001019/ScoringFiles/PGS001019.txt.gz
PGS001020
(GBE_BIN_FC50006160)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Attending social / leisure activities (regular attendance at an adult education class) social interaction measurement 220
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001020/ScoringFiles/PGS001020.txt.gz
PGS001021
(GBE_BIN1980)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Feelings of worry or anxiety worry measurement,
anxiety measurement
9,747
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001021/ScoringFiles/PGS001021.txt.gz
PGS001022
(GBE_BIN2000)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Worry too long after an embarrassing experience worry measurement 7,714
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001022/ScoringFiles/PGS001022.txt.gz
PGS001396
(GBE_QT_FC1002060)
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Frequency of unenthusiasm / disinterest in last 2 weeks emotional symptom measurement 2,431
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001396/ScoringFiles/PGS001396.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM007843 PGS001016
(GBE_BIN1950)
PSS003637|
African Ancestry|
6,118 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sensitivity / hurt feelings AUROC: 0.59163 [0.57735, 0.60591] : 0.0326
Incremental AUROC (full-covars): -0.01552
PGS R2 (no covariates): 7e-05
PGS AUROC (no covariates): 0.49648 [0.48187, 0.5111]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007844 PGS001016
(GBE_BIN1950)
PSS003638|
East Asian Ancestry|
1,534 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sensitivity / hurt feelings AUROC: 0.61857 [0.59048, 0.64665] PGS R2 (no covariates): 0.00285
PGS AUROC (no covariates): 0.52442 [0.49546, 0.55337]
: 0.06515
Incremental AUROC (full-covars): 0.00123
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007845 PGS001016
(GBE_BIN1950)
PSS003639|
European Ancestry|
24,064 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sensitivity / hurt feelings AUROC: 0.60838 [0.60128, 0.61549] : 0.04732
Incremental AUROC (full-covars): 0.01171
PGS R2 (no covariates): 0.00998
PGS AUROC (no covariates): 0.54753 [0.54024, 0.55481]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007846 PGS001016
(GBE_BIN1950)
PSS003640|
South Asian Ancestry|
7,159 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sensitivity / hurt feelings AUROC: 0.60244 [0.58913, 0.61576] : 0.03988
Incremental AUROC (full-covars): 0.00657
PGS R2 (no covariates): 0.00436
PGS AUROC (no covariates): 0.53424 [0.5206, 0.54787]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007847 PGS001016
(GBE_BIN1950)
PSS003641|
European Ancestry|
65,709 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Sensitivity / hurt feelings AUROC: 0.62016 [0.61586, 0.62446] : 0.0571
Incremental AUROC (full-covars): 0.01553
PGS R2 (no covariates): 0.00873
PGS AUROC (no covariates): 0.54593 [0.5415, 0.55036]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007848 PGS001017
(GBE_BIN2010)
PSS003652|
African Ancestry|
5,987 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Suffer from 'nerves' AUROC: 0.51358 [0.49307, 0.53409] : 0.00091
Incremental AUROC (full-covars): -0.01868
PGS R2 (no covariates): 0.0002
PGS AUROC (no covariates): 0.49271 [0.47201, 0.51341]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007849 PGS001017
(GBE_BIN2010)
PSS003653|
East Asian Ancestry|
1,473 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Suffer from 'nerves' AUROC: 0.56758 [0.53117, 0.604] : 0.01953
Incremental AUROC (full-covars): -0.01086
PGS R2 (no covariates): 0.00022
PGS AUROC (no covariates): 0.51056 [0.47283, 0.54828]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007850 PGS001017
(GBE_BIN2010)
PSS003654|
European Ancestry|
23,768 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Suffer from 'nerves' AUROC: 0.56488 [0.556, 0.57377] : 0.01344
Incremental AUROC (full-covars): 0.00629
PGS R2 (no covariates): 0.00341
PGS AUROC (no covariates): 0.53323 [0.52425, 0.54221]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007851 PGS001017
(GBE_BIN2010)
PSS003655|
South Asian Ancestry|
6,958 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Suffer from 'nerves' AUROC: 0.58706 [0.57106, 0.60305] : 0.02294
Incremental AUROC (full-covars): -0.00056
PGS R2 (no covariates): 0.00138
PGS AUROC (no covariates): 0.52168 [0.50524, 0.53812]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007852 PGS001017
(GBE_BIN2010)
PSS003656|
European Ancestry|
65,185 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Suffer from 'nerves' AUROC: 0.55991 [0.55463, 0.56519] : 0.01151
Incremental AUROC (full-covars): 0.01586
PGS R2 (no covariates): 0.00563
PGS AUROC (no covariates): 0.5416 [0.53628, 0.54693]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007853 PGS001018
(GBE_BIN_FC10006160)
PSS003741|
African Ancestry|
6,383 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) AUROC: 0.57396 [0.5576, 0.59032] : 0.01675
Incremental AUROC (full-covars): -0.00782
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.49703 [0.48018, 0.51389]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007854 PGS001018
(GBE_BIN_FC10006160)
PSS003742|
East Asian Ancestry|
1,633 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) AUROC: 0.57527 [0.54681, 0.60374] : 0.02162
Incremental AUROC (full-covars): -0.01137
PGS R2 (no covariates): 0.00034
PGS AUROC (no covariates): 0.48407 [0.4551, 0.51303]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007855 PGS001018
(GBE_BIN_FC10006160)
PSS003743|
European Ancestry|
24,772 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) AUROC: 0.58275 [0.57492, 0.59058] : 0.02479
Incremental AUROC (full-covars): 0.00287
PGS R2 (no covariates): 0.00278
PGS AUROC (no covariates): 0.52778 [0.51977, 0.53579]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007856 PGS001018
(GBE_BIN_FC10006160)
PSS003744|
South Asian Ancestry|
7,477 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) AUROC: 0.55963 [0.54607, 0.5732] : 0.01282
Incremental AUROC (full-covars): -0.00061
PGS R2 (no covariates): 0.00074
PGS AUROC (no covariates): 0.51312 [0.49938, 0.52686]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007857 PGS001018
(GBE_BIN_FC10006160)
PSS003745|
European Ancestry|
67,254 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend any of the followings in once a week or more often: sports club, gym, pub, social club, religious group, adult edication class, or other group activity) AUROC: 0.54214 [0.53736, 0.54692] : 0.00644
Incremental AUROC (full-covars): 0.00852
PGS R2 (no covariates): 0.00253
PGS AUROC (no covariates): 0.52663 [0.52182, 0.53145]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007858 PGS001019
(GBE_BIN_FC20006160)
PSS003835|
African Ancestry|
3,021 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) AUROC: 0.54407 [0.52357, 0.56457] : 0.00813
Incremental AUROC (full-covars): -0.00783
PGS R2 (no covariates): 0.00123
PGS AUROC (no covariates): 0.51554 [0.49496, 0.53612]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007859 PGS001019
(GBE_BIN_FC20006160)
PSS003836|
East Asian Ancestry|
1,085 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) AUROC: 0.58246 [0.5482, 0.61672] : 0.0292
Incremental AUROC (full-covars): 0.02535
PGS R2 (no covariates): 0.01412
PGS AUROC (no covariates): 0.55974 [0.52518, 0.5943]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007860 PGS001019
(GBE_BIN_FC20006160)
PSS003837|
European Ancestry|
15,258 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) AUROC: 0.57507 [0.56602, 0.58412] : 0.02282
Incremental AUROC (full-covars): 0.00636
PGS R2 (no covariates): 0.00715
PGS AUROC (no covariates): 0.54225 [0.53311, 0.55138]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007861 PGS001019
(GBE_BIN_FC20006160)
PSS003838|
South Asian Ancestry|
4,460 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) AUROC: 0.5442 [0.527, 0.5614] : 0.00767
Incremental AUROC (full-covars): -0.01443
PGS R2 (no covariates): 0.00058
PGS AUROC (no covariates): 0.50999 [0.49273, 0.52726]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007862 PGS001019
(GBE_BIN_FC20006160)
PSS003839|
European Ancestry|
41,646 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend sports club or gym in once a week or more often) AUROC: 0.55465 [0.54914, 0.56015] : 0.01246
Incremental AUROC (full-covars): 0.02052
PGS R2 (no covariates): 0.0089
PGS AUROC (no covariates): 0.54635 [0.54083, 0.55186]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007863 PGS001020
(GBE_BIN_FC50006160)
PSS003964|
African Ancestry|
2,080 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) AUROC: 0.62457 [0.59746, 0.65168] : 0.05611
Incremental AUROC (full-covars): -0.00161
PGS R2 (no covariates): 4e-05
PGS AUROC (no covariates): 0.50528 [0.47691, 0.53364]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007864 PGS001020
(GBE_BIN_FC50006160)
PSS003965|
East Asian Ancestry|
779 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) AUROC: 0.65214 [0.60399, 0.70029] : 0.08858
Incremental AUROC (full-covars): -0.016
PGS R2 (no covariates): 0.00657
PGS AUROC (no covariates): 0.44592 [0.39358, 0.49825]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007865 PGS001020
(GBE_BIN_FC50006160)
PSS003966|
European Ancestry|
9,800 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) AUROC: 0.63249 [0.61991, 0.64506] : 0.05833
Incremental AUROC (full-covars): 0.00299
PGS R2 (no covariates): 0.00271
PGS AUROC (no covariates): 0.52692 [0.51362, 0.54021]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007866 PGS001020
(GBE_BIN_FC50006160)
PSS003967|
South Asian Ancestry|
3,118 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) AUROC: 0.60534 [0.57645, 0.63422] : 0.03531
Incremental AUROC (full-covars): 0.00261
PGS R2 (no covariates): 0.00153
PGS AUROC (no covariates): 0.52735 [0.49684, 0.55785]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007867 PGS001020
(GBE_BIN_FC50006160)
PSS003968|
European Ancestry|
26,122 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Leisure/social activities (attend adult edication class in once a week or more often) AUROC: 0.63479 [0.62646, 0.64311] : 0.05542
Incremental AUROC (full-covars): 0.00193
PGS R2 (no covariates): 0.00149
PGS AUROC (no covariates): 0.5218 [0.51302, 0.53058]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007868 PGS001021
(GBE_BIN1980)
PSS003642|
African Ancestry|
6,104 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worrier / anxious feelings AUROC: 0.60438 [0.59021, 0.61855] : 0.04352
Incremental AUROC (full-covars): -0.00571
PGS R2 (no covariates): 0.00129
PGS AUROC (no covariates): 0.51656 [0.50201, 0.53111]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007869 PGS001021
(GBE_BIN1980)
PSS003643|
East Asian Ancestry|
1,544 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worrier / anxious feelings AUROC: 0.58907 [0.5608, 0.61733] : 0.03544
Incremental AUROC (full-covars): 0.01078
PGS R2 (no covariates): 0.0074
PGS AUROC (no covariates): 0.54082 [0.51208, 0.56956]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007870 PGS001021
(GBE_BIN1980)
PSS003644|
European Ancestry|
24,170 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worrier / anxious feelings AUROC: 0.6078 [0.60064, 0.61496] : 0.04664
Incremental AUROC (full-covars): 0.01418
PGS R2 (no covariates): 0.01254
PGS AUROC (no covariates): 0.55518 [0.54786, 0.56249]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007871 PGS001021
(GBE_BIN1980)
PSS003645|
South Asian Ancestry|
7,170 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worrier / anxious feelings AUROC: 0.59978 [0.58669, 0.61287] : 0.03875
Incremental AUROC (full-covars): -0.00373
PGS R2 (no covariates): 0.00244
PGS AUROC (no covariates): 0.5253 [0.51187, 0.53873]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007872 PGS001021
(GBE_BIN1980)
PSS003646|
European Ancestry|
65,798 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worrier / anxious feelings AUROC: 0.6164 [0.61209, 0.62072] : 0.05295
Incremental AUROC (full-covars): 0.0259
PGS R2 (no covariates): 0.01465
PGS AUROC (no covariates): 0.55972 [0.5553, 0.56414]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007873 PGS001022
(GBE_BIN2000)
PSS003647|
African Ancestry|
6,089 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worry too long after embarrassment AUROC: 0.56572 [0.55125, 0.58019] : 0.01766
Incremental AUROC (full-covars): -0.00878
PGS R2 (no covariates): 0.00047
PGS AUROC (no covariates): 0.50946 [0.49481, 0.52411]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007874 PGS001022
(GBE_BIN2000)
PSS003648|
East Asian Ancestry|
1,530 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worry too long after embarrassment AUROC: 0.56492 [0.5358, 0.59403] : 0.01813
Incremental AUROC (full-covars): -0.0008
PGS R2 (no covariates): 0.00097
PGS AUROC (no covariates): 0.52058 [0.49125, 0.5499]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007875 PGS001022
(GBE_BIN2000)
PSS003649|
European Ancestry|
23,849 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worry too long after embarrassment AUROC: 0.58127 [0.57406, 0.58848] : 0.02677
Incremental AUROC (full-covars): 0.01383
PGS R2 (no covariates): 0.00912
PGS AUROC (no covariates): 0.54606 [0.53877, 0.55335]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007876 PGS001022
(GBE_BIN2000)
PSS003650|
South Asian Ancestry|
6,993 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worry too long after embarrassment AUROC: 0.56486 [0.55147, 0.57825] : 0.01811
Incremental AUROC (full-covars): 0.00478
PGS R2 (no covariates): 0.00488
PGS AUROC (no covariates): 0.53067 [0.51717, 0.54417]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007877 PGS001022
(GBE_BIN2000)
PSS003651|
European Ancestry|
64,908 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Worry too long after embarrassment AUROC: 0.59904 [0.5947, 0.60337] : 0.03927
Incremental AUROC (full-covars): 0.01689
PGS R2 (no covariates): 0.01075
PGS AUROC (no covariates): 0.55091 [0.5465, 0.55532]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007245 PGS001396
(GBE_QT_FC1002060)
PSS007581|
African Ancestry|
5,837 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks : 0.00813 [0.00379, 0.01248]
Incremental R2 (full-covars): -0.00053
PGS R2 (no covariates): 0.00015 [-0.00044, 0.00073]
age, sex, UKB array type, Genotype PCs
PPM007246 PGS001396
(GBE_QT_FC1002060)
PSS007582|
East Asian Ancestry|
1,496 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks : 0.02489 [0.01031, 0.03947]
Incremental R2 (full-covars): -0.00242
PGS R2 (no covariates): 0.0007 [-0.00181, 0.00321]
age, sex, UKB array type, Genotype PCs
PPM007247 PGS001396
(GBE_QT_FC1002060)
PSS007583|
European Ancestry|
23,872 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks : 0.023 [0.01932, 0.02668]
Incremental R2 (full-covars): 0.00212
PGS R2 (no covariates): 0.00251 [0.00127, 0.00376]
age, sex, UKB array type, Genotype PCs
PPM007248 PGS001396
(GBE_QT_FC1002060)
PSS007584|
South Asian Ancestry|
6,548 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks : 0.00941 [0.00515, 0.01366]
Incremental R2 (full-covars): -0.00072
PGS R2 (no covariates): 0.0 [-0.00005, 0.00005]
age, sex, UKB array type, Genotype PCs
PPM007249 PGS001396
(GBE_QT_FC1002060)
PSS007585|
European Ancestry|
65,413 individuals
PGP000244 |
Tanigawa Y et al. medRxiv (2021)
|Pre
Reported Trait: Freq. of unenthusiasm / disinterest in last 2 weeks : 0.01367 [0.01193, 0.01541]
Incremental R2 (full-covars): 0.00193
PGS R2 (no covariates): 0.00206 [0.00138, 0.00274]
age, sex, UKB array type, Genotype PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS003644
[
  • 13,973 cases
  • , 10,197 controls
]
European non-white British ancestry UKB
PSS003645
[
  • 3,970 cases
  • , 3,200 controls
]
South Asian UKB
PSS003646
[
  • 37,860 cases
  • , 27,938 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS003647
[
  • 2,619 cases
  • , 3,470 controls
]
African unspecified UKB
PSS003648
[
  • 605 cases
  • , 925 controls
]
East Asian UKB
PSS003649
[
  • 11,647 cases
  • , 12,202 controls
]
European non-white British ancestry UKB
PSS003650
[
  • 3,557 cases
  • , 3,436 controls
]
South Asian UKB
PSS003651
[
  • 31,708 cases
  • , 33,200 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS003652
[
  • 915 cases
  • , 5,072 controls
]
African unspecified UKB
PSS003653
[
  • 294 cases
  • , 1,179 controls
]
East Asian UKB
PSS003654
[
  • 4,960 cases
  • , 18,808 controls
]
European non-white British ancestry UKB
PSS003655
[
  • 1,471 cases
  • , 5,487 controls
]
South Asian UKB
PSS003656
[
  • 14,228 cases
  • , 50,957 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS003835
[
  • 1,494 cases
  • , 1,527 controls
]
African unspecified UKB
PSS003836
[
  • 456 cases
  • , 629 controls
]
East Asian UKB
PSS003837
[
  • 8,025 cases
  • , 7,233 controls
]
European non-white British ancestry UKB
PSS003838
[
  • 1,790 cases
  • , 2,670 controls
]
South Asian UKB
PSS003839
[
  • 21,289 cases
  • , 20,357 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS003964
[
  • 535 cases
  • , 1,545 controls
]
African unspecified UKB
PSS003965
[
  • 135 cases
  • , 644 controls
]
East Asian UKB
PSS003966
[
  • 2,403 cases
  • , 7,397 controls
]
European non-white British ancestry UKB
PSS003967
[
  • 405 cases
  • , 2,713 controls
]
South Asian UKB
PSS003968
[
  • 5,233 cases
  • , 20,889 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS003741
[
  • 4,891 cases
  • , 1,492 controls
]
African unspecified UKB
PSS003742
[
  • 1,018 cases
  • , 615 controls
]
East Asian UKB
PSS003743
[
  • 17,791 cases
  • , 6,981 controls
]
European non-white British ancestry UKB
PSS003744
[
  • 4,862 cases
  • , 2,615 controls
]
South Asian UKB
PSS003745
[
  • 47,929 cases
  • , 19,325 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007581 5,837 individuals African unspecified UKB
PSS007582 1,496 individuals East Asian UKB
PSS007583 23,872 individuals European non-white British ancestry UKB
PSS007584 6,548 individuals South Asian UKB
PSS007585 65,413 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS003637
[
  • 2,629 cases
  • , 3,489 controls
]
African unspecified UKB
PSS003638
[
  • 681 cases
  • , 853 controls
]
East Asian UKB
PSS003639
[
  • 13,147 cases
  • , 10,917 controls
]
European non-white British ancestry UKB
PSS003640
[
  • 4,355 cases
  • , 2,804 controls
]
South Asian UKB
PSS003641
[
  • 37,128 cases
  • , 28,581 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS003642
[
  • 2,702 cases
  • , 3,402 controls
]
African unspecified UKB
PSS003643
[
  • 746 cases
  • , 798 controls
]
East Asian UKB