Trait: Sleep Disorder

Experimental Factor Ontology (EFO) Information
Identifier EFO_0008568
Description A change from the patient's baseline sleeping pattern, in the hours slept and/or an alteration/dysfunction in the stages of sleep. [NCIT: C3376]
Trait category
Neurological disorder
Synonyms 9 synonyms
  • Disturbances, Sleep
  • Sleep Disorders
  • Sleep Disturbance
  • Sleep Disturbances
  • disturbances, sleep
  • parasomnia
  • sleep disorder
  • sleep disturbance
  • sleep disturbances
Mapped terms 5 mapped terms
  • ICD10:G47
  • MONDO:0100081
  • MedDRA:10040984
  • NCIT:C3376
  • NCIt:C3376
Child trait(s) 6 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "Sleep Disorder" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS000756
(GRS3_Nar)
PGP000162 |
Ouyang H et al. Ann Transl Med (2020)
Narcolepsy narcolepsy-cataplexy syndrome 32
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000756/ScoringFiles/PGS000756.txt.gz
PGS000757
(GRS4_Nar)
PGP000162 |
Ouyang H et al. Ann Transl Med (2020)
Narcolepsy narcolepsy-cataplexy syndrome 5
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000757/ScoringFiles/PGS000757.txt.gz
PGS000908
(PRS_Insomnia)
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Insomnia insomnia 2,746,982
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000908/ScoringFiles/PGS000908.txt.gz
PGS000926
(GBE_QT_FC1001220)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Daytime dozing / sleeping (narcolepsy) narcolepsy 4,194
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000926/ScoringFiles/PGS000926.txt.gz
PGS001932
(portability-PLR_insomnia)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sleeplessness / insomnia insomnia 37,712
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001932/ScoringFiles/PGS001932.txt.gz
PGS001995
(portability-PLR_narcolepsy)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Daytime dozing / sleeping (narcolepsy) narcolepsy 27,143
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001995/ScoringFiles/PGS001995.txt.gz
PGS002144
(portability-ldpred2_hard_falling_asleep)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Trouble falling asleep Sleep Disorder 539,784
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002144/ScoringFiles/PGS002144.txt.gz
PGS002149
(portability-ldpred2_insomnia)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sleeplessness / insomnia insomnia 926,585
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002149/ScoringFiles/PGS002149.txt.gz
PGS002212
(portability-ldpred2_narcolepsy)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Daytime dozing / sleeping (narcolepsy) narcolepsy 893,802
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002212/ScoringFiles/PGS002212.txt.gz
PGS003204
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 4,360
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003204/ScoringFiles/PGS003204.txt.gz
PGS003205
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 5,300
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003205/ScoringFiles/PGS003205.txt.gz
PGS003206
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 9,873
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003206/ScoringFiles/PGS003206.txt.gz
PGS003207
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 355
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003207/ScoringFiles/PGS003207.txt.gz
PGS003208
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 12,076
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003208/ScoringFiles/PGS003208.txt.gz
PGS003209
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 328,671
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003209/ScoringFiles/PGS003209.txt.gz
PGS003210
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 40,992
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003210/ScoringFiles/PGS003210.txt.gz
PGS003211
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 39,223
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003211/ScoringFiles/PGS003211.txt.gz
PGS003212
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 7,601,206
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003212/ScoringFiles/PGS003212.txt.gz
PGS003213
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 1,111,194
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003213/ScoringFiles/PGS003213.txt.gz
PGS003214
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_LASSOSUM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 5,812
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003214/ScoringFiles/PGS003214.txt.gz
PGS003215
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PT_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 1,209
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003215/ScoringFiles/PGS003215.txt.gz
PGS003216
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PLINK_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 688
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003216/ScoringFiles/PGS003216.txt.gz
PGS003217
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_DBSLMM_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 46
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003217/ScoringFiles/PGS003217.txt.gz
PGS003218
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PRSCS_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Sleep apnea sleep apnea 12,097
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003218/ScoringFiles/PGS003218.txt.gz
PGS003319
(ExPRSweb_Insomnia_1160_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 578,551
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003319/ScoringFiles/PGS003319.txt.gz
PGS003320
(ExPRSweb_Insomnia_1160_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 147
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003320/ScoringFiles/PGS003320.txt.gz
PGS003321
(ExPRSweb_Insomnia_1160_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 148
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003321/ScoringFiles/PGS003321.txt.gz
PGS003322
(ExPRSweb_Insomnia_1160_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 8,590,163
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003322/ScoringFiles/PGS003322.txt.gz
PGS003323
(ExPRSweb_Insomnia_1160_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 1,113,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003323/ScoringFiles/PGS003323.txt.gz
PGS003324
(ExPRSweb_Insomnia_1200_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 464,576
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003324/ScoringFiles/PGS003324.txt.gz
PGS003325
(ExPRSweb_Insomnia_1200_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 28,289
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003325/ScoringFiles/PGS003325.txt.gz
PGS003326
(ExPRSweb_Insomnia_1200_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 27,462
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003326/ScoringFiles/PGS003326.txt.gz
PGS003327
(ExPRSweb_Insomnia_1200_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 6,214,923
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003327/ScoringFiles/PGS003327.txt.gz
PGS003328
(ExPRSweb_Insomnia_1200_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Insomnia insomnia 1,065,129
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003328/ScoringFiles/PGS003328.txt.gz
PGS003414
(PRS47_RBD)
PGP000427 |
Krohn L et al. Nat Commun (2022)
REM sleep behavior disorder REM sleep behavior disorder 47
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003414/ScoringFiles/PGS003414.txt.gz
PGS003479
(LDPred2_SleepApnea)
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Obstructive sleep apnea obstructive sleep apnea 836,839
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003479/ScoringFiles/PGS003479.txt.gz
PGS003857
(GRS18_BMIunadj)
PGP000496 |
Sofer T et al. EBioMedicine (2023)
Obstructive sleep apnea obstructive sleep apnea 18
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003857/ScoringFiles/PGS003857.txt.gz
PGS003858
(GRS6_BMIadj)
PGP000496 |
Sofer T et al. EBioMedicine (2023)
Obstructive sleep apnea (BMI adjusted) obstructive sleep apnea 6
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003858/ScoringFiles/PGS003858.txt.gz
PGS004452
(disease.G47.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
G47 (Sleep disorders) Sleep Disorder 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004452/ScoringFiles/PGS004452.txt.gz
PGS004522
(meta.G47.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
G47 (Sleep disorders) Sleep Disorder 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004522/ScoringFiles/PGS004522.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001925 PGS000756
(GRS3_Nar)
PSS000966|
East Asian Ancestry|
2,884 individuals
PGP000162 |
Ouyang H et al. Ann Transl Med (2020)
Reported Trait: Incident narcolepsy OR: 1.149 [1.119, 1.181] Odds Ratio (OR, high vs low risk): 2.586 [2.109, 3.173] Individuals with a high polygenic risk had a score ≥28. Individuals with a low polygenic risk had a score <25.
PPM001926 PGS000756
(GRS3_Nar)
PSS000966|
East Asian Ancestry|
2,884 individuals
PGP000162 |
Ouyang H et al. Ann Transl Med (2020)
Reported Trait: Incident narcolepsy OR: 1.152 [1.12, 1.185] AUROC: 0.723 Odds Ratio (OR, high vs low risk): 2.602 [2.097, 3.232] Gender Individuals with a high polygenic risk had a score ≥28. Individuals with a low polygenic risk had a score <25.
PPM001927 PGS000757
(GRS4_Nar)
PSS000966|
East Asian Ancestry|
2,884 individuals
PGP000162 |
Ouyang H et al. Ann Transl Med (2020)
Reported Trait: Incident narcolepsy OR: 1.449 [1.367, 1.536] Odds Ratio (OR, high vs low risk): 4.298 [3.378, 5.481] Individuals with a high polygenic risk had a score ≥8. Individuals with a low polygenic risk had a score <6.
PPM001928 PGS000757
(GRS4_Nar)
PSS000966|
East Asian Ancestry|
2,884 individuals
PGP000162 |
Ouyang H et al. Ann Transl Med (2020)
Reported Trait: Incident narcolepsy OR: 1.442 [1.357, 1.534] AUROC: 0.736 Odds Ratio (OR, high vs low risk): 4.157 [3.224, 5.371] Gender Individuals with a high polygenic risk had a score ≥8. Individuals with a low polygenic risk had a score <6.
PPM002950 PGS000908
(PRS_Insomnia)
PSS001293|
European Ancestry|
5,713 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Sertraline takers OR: 1.06 [0.99, 1.14] Variance explained (Nagelkerke's R2*100): 0.09 sex, age at study enrollment, genetic PCs 1-20
PPM002951 PGS000908
(PRS_Insomnia)
PSS001289|
European Ancestry|
4,362 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Escitalopram takers OR: 1.12 [1.03, 1.21] Variance explained (Nagelkerke's R2*100): 0.27 sex, age at study enrollment, genetic PCs 1-20
PPM002952 PGS000908
(PRS_Insomnia)
PSS001294|
European Ancestry|
3,964 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Venlafaxine takers OR: 1.03 [0.95, 1.11] Variance explained (Nagelkerke's R2*100): 0.02 sex, age at study enrollment, genetic PCs 1-20
PPM002953 PGS000908
(PRS_Insomnia)
PSS001285|
European Ancestry|
1,655 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Amitriptyline takers OR: 1.28 [1.07, 1.52] Variance explained (Nagelkerke's R2*100): 1.03 sex, age at study enrollment, genetic PCs 1-20
PPM002954 PGS000908
(PRS_Insomnia)
PSS001291|
European Ancestry|
1,986 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Mirtazapine takers OR: 1.03 [0.88, 1.2] Variance explained (Nagelkerke's R2*100): 0.01 sex, age at study enrollment, genetic PCs 1-20
PPM002955 PGS000908
(PRS_Insomnia)
PSS001287|
European Ancestry|
2,523 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Desvenlafaxine takers OR: 1.13 [1.03, 1.25] Variance explained (Nagelkerke's R2*100): 0.38 sex, age at study enrollment, genetic PCs 1-20
PPM002956 PGS000908
(PRS_Insomnia)
PSS001286|
European Ancestry|
2,585 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Citalopram takers OR: 1.08 [0.96, 1.21] Variance explained (Nagelkerke's R2*100): 0.12 sex, age at study enrollment, genetic PCs 1-20
PPM002957 PGS000908
(PRS_Insomnia)
PSS001290|
European Ancestry|
3,665 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Fluoxetine takers OR: 1.03 [0.94, 1.13] Variance explained (Nagelkerke's R2*100): 0.02 sex, age at study enrollment, genetic PCs 1-20
PPM002958 PGS000908
(PRS_Insomnia)
PSS001288|
European Ancestry|
1,994 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Duloxetine takers OR: 1.14 [1.02, 1.28] Variance explained (Nagelkerke's R2*100): 0.4 sex, age at study enrollment, genetic PCs 1-20
PPM002959 PGS000908
(PRS_Insomnia)
PSS001292|
European Ancestry|
1,577 individuals
PGP000238 |
Campos AI et al. Commun Med (Lond) (2021)
Reported Trait: Insomnia in Paroxetine takers OR: 1.16 [1.01, 1.33] Variance explained (Nagelkerke's R2*100): 0.47 sex, age at study enrollment, genetic PCs 1-20
PPM007457 PGS000926
(GBE_QT_FC1001220)
PSS007536|
African Ancestry|
6,254 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) : 0.02468 [0.01723, 0.03213]
Incremental R2 (full-covars): -0.00089
PGS R2 (no covariates): 0.00034 [-0.00056, 0.00125]
age, sex, UKB array type, Genotype PCs
PPM007458 PGS000926
(GBE_QT_FC1001220)
PSS007537|
East Asian Ancestry|
1,629 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Incremental R2 (full-covars): 0.00183
: 0.03667 [0.01919, 0.05415]
PGS R2 (no covariates): 0.00244 [-0.00223, 0.0071]
age, sex, UKB array type, Genotype PCs
PPM007459 PGS000926
(GBE_QT_FC1001220)
PSS007538|
European Ancestry|
24,713 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) : 0.02067 [0.01717, 0.02417]
Incremental R2 (full-covars): 0.00439
PGS R2 (no covariates): 0.00422 [0.00261, 0.00583]
age, sex, UKB array type, Genotype PCs
PPM007460 PGS000926
(GBE_QT_FC1001220)
PSS007539|
South Asian Ancestry|
7,410 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) : 0.0158 [0.01032, 0.02128]
Incremental R2 (full-covars): 0.00236
PGS R2 (no covariates): 0.00251 [0.0003, 0.00473]
age, sex, UKB array type, Genotype PCs
PPM007461 PGS000926
(GBE_QT_FC1001220)
PSS007540|
European Ancestry|
67,196 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) : 0.02284 [0.02061, 0.02507]
Incremental R2 (full-covars): 0.00532
PGS R2 (no covariates): 0.00542 [0.00431, 0.00652]
age, sex, UKB array type, Genotype PCs
PPM010331 PGS001932
(portability-PLR_insomnia)
PSS009419|
European Ancestry|
19,978 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.1248 [0.1111, 0.1384] sex, age, birth date, deprivation index, 16 PCs
PPM010332 PGS001932
(portability-PLR_insomnia)
PSS009193|
European Ancestry|
4,116 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.1003 [0.0699, 0.1305] sex, age, birth date, deprivation index, 16 PCs
PPM010333 PGS001932
(portability-PLR_insomnia)
PSS008747|
European Ancestry|
6,626 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.1093 [0.0854, 0.133] sex, age, birth date, deprivation index, 16 PCs
PPM010334 PGS001932
(portability-PLR_insomnia)
PSS008521|
Greater Middle Eastern Ancestry|
1,153 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.0776 [0.0195, 0.1353] sex, age, birth date, deprivation index, 16 PCs
PPM010335 PGS001932
(portability-PLR_insomnia)
PSS008299|
South Asian Ancestry|
6,199 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.0768 [0.052, 0.1015] sex, age, birth date, deprivation index, 16 PCs
PPM010337 PGS001932
(portability-PLR_insomnia)
PSS007863|
African Ancestry|
2,460 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.0475 [0.0078, 0.087] sex, age, birth date, deprivation index, 16 PCs
PPM010338 PGS001932
(portability-PLR_insomnia)
PSS008967|
African Ancestry|
3,863 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.033 [0.0013, 0.0645] sex, age, birth date, deprivation index, 16 PCs
PPM010336 PGS001932
(portability-PLR_insomnia)
PSS008076|
East Asian Ancestry|
1,788 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.0473 sex, age, birth date, deprivation index, 16 PCs
PPM010835 PGS001995
(portability-PLR_narcolepsy)
PSS009478|
European Ancestry|
19,922 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0959 [0.0822, 0.1097] sex, age, birth date, deprivation index, 16 PCs
PPM010836 PGS001995
(portability-PLR_narcolepsy)
PSS009252|
European Ancestry|
4,057 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0898 [0.0591, 0.1203] sex, age, birth date, deprivation index, 16 PCs
PPM010837 PGS001995
(portability-PLR_narcolepsy)
PSS008806|
European Ancestry|
6,571 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0631 [0.039, 0.0872] sex, age, birth date, deprivation index, 16 PCs
PPM010838 PGS001995
(portability-PLR_narcolepsy)
PSS008580|
Greater Middle Eastern Ancestry|
1,078 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0622 [0.002, 0.1221] sex, age, birth date, deprivation index, 16 PCs
PPM010839 PGS001995
(portability-PLR_narcolepsy)
PSS008358|
South Asian Ancestry|
6,001 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0739 [0.0487, 0.0991] sex, age, birth date, deprivation index, 16 PCs
PPM010840 PGS001995
(portability-PLR_narcolepsy)
PSS008135|
East Asian Ancestry|
1,752 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0367 [-0.0104, 0.0837] sex, age, birth date, deprivation index, 16 PCs
PPM010841 PGS001995
(portability-PLR_narcolepsy)
PSS007922|
African Ancestry|
2,395 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0267 [-0.0135, 0.0668] sex, age, birth date, deprivation index, 16 PCs
PPM010842 PGS001995
(portability-PLR_narcolepsy)
PSS009026|
African Ancestry|
3,750 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0356 [0.0036, 0.0677] sex, age, birth date, deprivation index, 16 PCs
PPM011999 PGS002144
(portability-ldpred2_hard_falling_asleep)
PSS009414|
European Ancestry|
2,491 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Trouble falling asleep Partial Correlation (partial-r): 0.0646 [0.0253, 0.1038] sex, age, birth date, deprivation index, 16 PCs
PPM012000 PGS002144
(portability-ldpred2_hard_falling_asleep)
PSS009188|
European Ancestry|
490 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Trouble falling asleep Partial Correlation (partial-r): 0.0519 [-0.0387, 0.1417] sex, age, birth date, deprivation index, 16 PCs
PPM012001 PGS002144
(portability-ldpred2_hard_falling_asleep)
PSS008742|
European Ancestry|
898 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Trouble falling asleep Partial Correlation (partial-r): -0.0252 [-0.0912, 0.041] sex, age, birth date, deprivation index, 16 PCs
PPM012002 PGS002144
(portability-ldpred2_hard_falling_asleep)
PSS008516|
Greater Middle Eastern Ancestry|
75 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Trouble falling asleep Partial Correlation (partial-r): 0.0283 [-0.2388, 0.2914] sex, age, birth date, deprivation index, 16 PCs
PPM012003 PGS002144
(portability-ldpred2_hard_falling_asleep)
PSS008294|
South Asian Ancestry|
311 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Trouble falling asleep Partial Correlation (partial-r): 0.062 [-0.0534, 0.1757] sex, age, birth date, deprivation index, 16 PCs
PPM012004 PGS002144
(portability-ldpred2_hard_falling_asleep)
PSS008071|
East Asian Ancestry|
147 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Trouble falling asleep Partial Correlation (partial-r): 0.0992 [-0.0763, 0.2688] sex, age, birth date, deprivation index, 16 PCs
PPM012005 PGS002144
(portability-ldpred2_hard_falling_asleep)
PSS007858|
African Ancestry|
149 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Trouble falling asleep Partial Correlation (partial-r): -0.0892 [-0.258, 0.085] sex, age, birth date, deprivation index, 16 PCs
PPM012006 PGS002144
(portability-ldpred2_hard_falling_asleep)
PSS008962|
African Ancestry|
151 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Trouble falling asleep Partial Correlation (partial-r): -0.0423 [-0.2123, 0.1301] sex, age, birth date, deprivation index, 16 PCs
PPM012040 PGS002149
(portability-ldpred2_insomnia)
PSS009193|
European Ancestry|
4,116 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.1208 [0.0905, 0.1508] sex, age, birth date, deprivation index, 16 PCs
PPM012039 PGS002149
(portability-ldpred2_insomnia)
PSS009419|
European Ancestry|
19,978 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.1411 [0.1275, 0.1547] sex, age, birth date, deprivation index, 16 PCs
PPM012041 PGS002149
(portability-ldpred2_insomnia)
PSS008747|
European Ancestry|
6,626 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.1253 [0.1015, 0.149] sex, age, birth date, deprivation index, 16 PCs
PPM012042 PGS002149
(portability-ldpred2_insomnia)
PSS008521|
Greater Middle Eastern Ancestry|
1,153 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.0852 [0.0271, 0.1427] sex, age, birth date, deprivation index, 16 PCs
PPM012043 PGS002149
(portability-ldpred2_insomnia)
PSS008299|
South Asian Ancestry|
6,199 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.0985 [0.0737, 0.1231] sex, age, birth date, deprivation index, 16 PCs
PPM012044 PGS002149
(portability-ldpred2_insomnia)
PSS008076|
East Asian Ancestry|
1,788 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.0345 [-0.0122, 0.081] sex, age, birth date, deprivation index, 16 PCs
PPM012045 PGS002149
(portability-ldpred2_insomnia)
PSS007863|
African Ancestry|
2,460 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.0283 [-0.0114, 0.0679] sex, age, birth date, deprivation index, 16 PCs
PPM012046 PGS002149
(portability-ldpred2_insomnia)
PSS008967|
African Ancestry|
3,863 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sleeplessness / insomnia Partial Correlation (partial-r): 0.0314 sex, age, birth date, deprivation index, 16 PCs
PPM012543 PGS002212
(portability-ldpred2_narcolepsy)
PSS009478|
European Ancestry|
19,922 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.1104 [0.0966, 0.1241] sex, age, birth date, deprivation index, 16 PCs
PPM012544 PGS002212
(portability-ldpred2_narcolepsy)
PSS009252|
European Ancestry|
4,057 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0922 [0.0616, 0.1227] sex, age, birth date, deprivation index, 16 PCs
PPM012545 PGS002212
(portability-ldpred2_narcolepsy)
PSS008806|
European Ancestry|
6,571 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0802 [0.0561, 0.1042] sex, age, birth date, deprivation index, 16 PCs
PPM012546 PGS002212
(portability-ldpred2_narcolepsy)
PSS008580|
Greater Middle Eastern Ancestry|
1,078 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0377 [-0.0227, 0.0977] sex, age, birth date, deprivation index, 16 PCs
PPM012547 PGS002212
(portability-ldpred2_narcolepsy)
PSS008358|
South Asian Ancestry|
6,001 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0784 [0.0531, 0.1035] sex, age, birth date, deprivation index, 16 PCs
PPM012548 PGS002212
(portability-ldpred2_narcolepsy)
PSS008135|
East Asian Ancestry|
1,752 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0407 [-0.0064, 0.0876] sex, age, birth date, deprivation index, 16 PCs
PPM012549 PGS002212
(portability-ldpred2_narcolepsy)
PSS007922|
African Ancestry|
2,395 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.05 [0.0098, 0.0901] sex, age, birth date, deprivation index, 16 PCs
PPM012550 PGS002212
(portability-ldpred2_narcolepsy)
PSS009026|
African Ancestry|
3,750 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Daytime dozing / sleeping (narcolepsy) Partial Correlation (partial-r): 0.0511 [0.019, 0.0831] sex, age, birth date, deprivation index, 16 PCs
PPM015959 PGS003204
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_LASSOSUM_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 0.983 [0.952, 1.014]
β: -0.0174 (0.016)
AUROC: 0.49 [0.482, 0.499] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015965 PGS003205
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PT_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 0.998 [0.967, 1.03]
β: -0.00225 (0.0161)
AUROC: 0.5 [0.491, 0.509] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015961 PGS003206
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PLINK_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 0.975 [0.945, 1.007]
β: -0.0252 (0.0162)
AUROC: 0.49 [0.48, 0.499] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015957 PGS003207
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_DBSLMM_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 0.975 [0.945, 1.005]
β: -0.0258 (0.016)
AUROC: 0.492 [0.484, 0.501] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015963 PGS003208
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PRSCS_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 1.016 [0.984, 1.048]
β: 0.0154 (0.0161)
AUROC: 0.505 [0.497, 0.514] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015953 PGS003209
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_LASSOSUM_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 1.053 [1.02, 1.087]
β: 0.0517 (0.0162)
AUROC: 0.514 [0.506, 0.523] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015956 PGS003210
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_PT_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 1.073 [1.04, 1.108]
β: 0.0708 (0.0162)
AUROC: 0.519 [0.51, 0.528] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015954 PGS003211
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_PLINK_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 1.061 [1.028, 1.096]
β: 0.0595 (0.0162)
AUROC: 0.515 [0.506, 0.525] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015952 PGS003212
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_DBSLMM_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 1.014 [0.982, 1.046]
β: 0.0135 (0.016)
AUROC: 0.496 [0.487, 0.504] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015955 PGS003213
(ExPRSweb_SleepApnea_G6-SLEEPAPNO_PRSCS_MGI_20211120)
PSS010012|
European Ancestry|
21,354 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 1.106 [1.071, 1.142]
β: 0.101 (0.0162)
AUROC: 0.527 [0.517, 0.536] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015960 PGS003214
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_LASSOSUM_UKB_20211120)
PSS010032|
European Ancestry|
203,685 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 1.004 [0.962, 1.047]
β: 0.00364 (0.0214)
AUROC: 0.5 [0.489, 0.513] Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015966 PGS003215
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PT_UKB_20211120)
PSS010032|
European Ancestry|
203,685 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 0.967 [0.928, 1.009]
β: -0.0331 (0.0215)
AUROC: 0.489 [0.477, 0.501] Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015962 PGS003216
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PLINK_UKB_20211120)
PSS010032|
European Ancestry|
203,685 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea β: -0.00819 (0.0214)
OR: 0.992 [0.951, 1.034]
AUROC: 0.497 [0.485, 0.509] Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015958 PGS003217
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_DBSLMM_UKB_20211120)
PSS010032|
European Ancestry|
203,685 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 1.021 [0.98, 1.064]
β: 0.0207 (0.0211)
AUROC: 0.485 [0.475, 0.495] Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015964 PGS003218
(ExPRSweb_SleepApnea_finngen-R4-G6-SLEEPAPNO_PRSCS_UKB_20211120)
PSS010032|
European Ancestry|
203,685 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Sleep Apnea OR: 1.003 [0.962, 1.046]
β: 0.00286 (0.0214)
AUROC: 0.5 [0.488, 0.512] Sex,birthYear,genotyping.array,PC1,PC2,PC3,PC4
PPM015908 PGS003319
(ExPRSweb_Insomnia_1160_LASSOSUM_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 0.978 [0.932, 1.028]
β: -0.0217 (0.025)
AUROC: 0.498 [0.486, 0.51] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015911 PGS003320
(ExPRSweb_Insomnia_1160_PT_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 0.977 [0.937, 1.02]
β: -0.0228 (0.0218)
AUROC: 0.494 [0.483, 0.505] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015909 PGS003321
(ExPRSweb_Insomnia_1160_PLINK_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 0.975 [0.934, 1.017]
β: -0.0258 (0.0218)
AUROC: 0.493 [0.481, 0.505] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015907 PGS003322
(ExPRSweb_Insomnia_1160_DBSLMM_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 0.97 [0.931, 1.01]
β: -0.0309 (0.0206)
AUROC: 0.492 [0.481, 0.504] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015910 PGS003323
(ExPRSweb_Insomnia_1160_PRSCS_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 0.988 [0.947, 1.031]
β: -0.0122 (0.0218)
AUROC: 0.499 [0.487, 0.511] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015913 PGS003324
(ExPRSweb_Insomnia_1200_LASSOSUM_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 1.026 [0.985, 1.069]
β: 0.0254 (0.0209)
AUROC: 0.507 [0.496, 0.518] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015916 PGS003325
(ExPRSweb_Insomnia_1200_PT_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 1.092 [1.048, 1.137]
β: 0.0876 (0.021)
AUROC: 0.524 [0.512, 0.535] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015914 PGS003326
(ExPRSweb_Insomnia_1200_PLINK_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 1.085 [1.041, 1.131]
β: 0.0817 (0.021)
AUROC: 0.522 [0.511, 0.534] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015912 PGS003327
(ExPRSweb_Insomnia_1200_DBSLMM_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 1.038 [0.997, 1.081]
β: 0.0375 (0.0206)
AUROC: 0.51 [0.499, 0.521] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM015915 PGS003328
(ExPRSweb_Insomnia_1200_PRSCS_MGI_20211120)
PSS010009|
European Ancestry|
18,641 individuals
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Reported Trait: Insomnia OR: 1.101 [1.056, 1.147]
β: 0.096 (0.021)
AUROC: 0.524 [0.513, 0.536] SEX,AGE,Batch,PC1,PC2,PC3,PC4
PPM017064 PGS003414
(PRS47_RBD)
PSS010109|
European Ancestry|
1,477 individuals
PGP000427 |
Krohn L et al. Nat Commun (2022)
Reported Trait: Isolated REM sleep behavior disorder AUROC: 0.614 [0.575, 0.654]
PPM017065 PGS003414
(PRS47_RBD)
PSS010110|
European Ancestry|
1,192 individuals
PGP000427 |
Krohn L et al. Nat Commun (2022)
Reported Trait: Probabable REM sleep behavior disorder (with Parkinson disease) AUROC: 0.597 [0.56, 0.634]
PPM017066 PGS003414
(PRS47_RBD)
PSS010111|
European Ancestry|
1,124 individuals
PGP000427 |
Krohn L et al. Nat Commun (2022)
Reported Trait: Probabable REM sleep behavior disorder AUROC: 0.548 [0.505, 0.59]
PPM017318 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: DBP β: 0.038 (0.093) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017319 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Eosinophils count β: 0.003 (0.002) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017320 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: FEV1/FVC ratio β: -0.035 (0.06) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017321 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Fasting insulin β: 0.156 (0.091) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017322 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: HbA1c β: 0.291 (0.122) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017323 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Hematocrit β: 0.039 (0.031) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017324 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Hemoglobin β: 0.014 (0.011) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017325 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: HOMA-B β: 1.851 (1.169) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017326 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: HOMA-IR β: 0.051 (0.03) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017327 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Heart rate β: 0.038 (0.106) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017328 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Insomnia β: 0.015 (0.049) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017329 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: LDL β: -0.358 (0.336) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017330 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Lymphocyte count β: 0.002 (0.007) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017331 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Mean arterial pressure β: 0.011 (0.102) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017333 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: RBC β: 0.003 (0.003) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017334 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Sleep duration β: 0.0 (0.013) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017335 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Total cholesterol β: -0.324 (0.391) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017336 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Triglycerides β: 0.725 (0.93) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017337 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: WBC β: 0.006 (0.018) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017338 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Waist hip ratio β: 0.002 (0.001) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017339 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: FEV1/FVC ratio β: 0.002 (0.018) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017380 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: DBP in obsese β: -0.084 (0.148) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017381 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: DBP in non-obsese β: 0.116 (0.118) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017382 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Fasting insulin in obsese β: 0.201 (0.161) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017383 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Fasting insulin in non-obsese β: 0.175 (0.089) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017384 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: HbA1c in obsese β: 0.052 (0.197) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017385 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: HbA1c in non-obsese β: 0.488 (0.151) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017386 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: HOMA-B in obsese β: 0.724 (2.105) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017387 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: HOMA-B in non-obsese β: 1.664 (1.084) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017388 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: HOMA-IR in obsese β: 0.076 (0.057) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017389 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: HOMA-IR in non-obsese β: 0.062 (0.029) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017390 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Waist hip ratio in obsese β: 0.002 (0.001) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017391 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Waist hip ratio in non-obsese β: 0.001 (0.001) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM017332 PGS003479
(LDPred2_SleepApnea)
PSS010185|
Hispanic or Latin American Ancestry|
1,115 individuals
PGP000456 |
Zhang Y et al. EBioMedicine (2022)
Reported Trait: Pulse pressure β: -0.073 (0.104) Age, sex, center, 5 genetic PCs, Hispanic/Latino background, BMI
PPM018710 PGS003857
(GRS18_BMIunadj)
PSS011076|
Multi-ancestry (including European)|
40,193 individuals
PGP000496 |
Sofer T et al. EBioMedicine (2023)
Reported Trait: BMI adjusted obstructive sleep apnea β: 0.014 (0.017) AUROC: 0.77 [0.75, 0.78] BMI, age, sex, genetic batch, PCs 1-10
PPM018709 PGS003857
(GRS18_BMIunadj)
PSS011076|
Multi-ancestry (including European)|
40,193 individuals
PGP000496 |
Sofer T et al. EBioMedicine (2023)
Reported Trait: BMI unadjusted obstructive sleep apnea β: 0.082 (0.016) AUROC: 0.66 [0.64, 0.67] age, sex, genetic batch, PCs 1-10
PPM018711 PGS003858
(GRS6_BMIadj)
PSS011076|
Multi-ancestry (including European)|
40,193 individuals
PGP000496 |
Sofer T et al. EBioMedicine (2023)
Reported Trait: BMI unadjusted obstructive sleep apnea β: 0.048 (0.015) AUROC: 0.62 [0.61, 0.64] age, sex, genetic batch, PCs 1-10
PPM018712 PGS003858
(GRS6_BMIadj)
PSS011076|
Multi-ancestry (including European)|
40,193 individuals
PGP000496 |
Sofer T et al. EBioMedicine (2023)
Reported Trait: BMI adjusted obstructive sleep apnea β: 0.066 (0.017) AUROC: 0.77 [0.76, 0.79] BMI, age, sex, genetic batch, PCs 1-10
PPM020567 PGS004452
(disease.G47.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: G47 (Sleep disorders) OR: 1.16879
PPM020637 PGS004522
(meta.G47.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: G47 (Sleep disorders) OR: 1.34952

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008516 75 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009414 2,491 individuals European UK (+ Ireland) UKB
PSS008135 1,752 individuals East Asian China (East Asia) UKB
PSS011364 56,192 individuals European UKB
PSS008521 1,153 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009419 19,978 individuals European UK (+ Ireland) UKB
PSS010109
[
  • 212 cases
  • , 1,265 controls
]
European 23andMe, WTCCC
PSS010110
[
  • 285 cases
  • , 907 controls
]
European 23andMe, WTCCC
PSS010111
[
  • 217 cases
  • , 907 controls
]
European 23andMe, WTCCC
PSS009188 490 individuals European Poland (NE Europe) UKB
PSS008806 6,571 individuals European Italy (South Europe) UKB
PSS008294 311 individuals South Asian India (South Asia) UKB
PSS009193 4,116 individuals European Poland (NE Europe) UKB
PSS008299 6,199 individuals South Asian India (South Asia) UKB
PSS007922 2,395 individuals African American or Afro-Caribbean Carribean UKB
PSS007536 6,254 individuals African unspecified UKB
PSS007537 1,629 individuals East Asian UKB
PSS007538 24,713 individuals European non-white British ancestry UKB
PSS007539 7,410 individuals South Asian UKB
PSS007540 67,196 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS010009 PheCode 327.4 (http://phewascatalog.org/); Binary
[
  • 2,830 cases
  • , 15,811 controls
]
European MGI
PSS000966 The narcolepsy patients had either hypocretin deficiency (CSF hypocretin-1 ≤110 pg/mL) or clear-cut cataplexy and HLA-DQB1*06:02.
[
  • 903 cases
  • , 1,981 controls
]
,
44.94 % Male samples
East Asian
(Han Chinese, Chinese)
NR
PSS010012 PheCode 327.3 (http://phewascatalog.org/); Binary
[
  • 5,443 cases
  • , 15,911 controls
]
European MGI
PSS010185 1,115 individuals,
41.1 % Male samples
Mean = 46.18 years Hispanic or Latin American HCHS, SOL
PSS008962 151 individuals African unspecified Nigeria (West Africa) UKB
PSS008580 1,078 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS009478 19,922 individuals European UK (+ Ireland) UKB
PSS008967 3,863 individuals African unspecified Nigeria (West Africa) UKB
PSS008071 147 individuals East Asian China (East Asia) UKB
PSS008076 1,788 individuals East Asian China (East Asia) UKB
PSS010032 PheCode 327.3 (http://phewascatalog.org/); Binary
[
  • 2,209 cases
  • , 201,476 controls
]
European UKB
PSS001285
[
  • 140 cases
  • , 1,515 controls
]
European AGDS
PSS001286
[
  • 367 cases
  • , 2,218 controls
]
European AGDS
PSS001287
[
  • 488 cases
  • , 2,035 controls
]
European AGDS
PSS001288
[
  • 382 cases
  • , 1,612 controls
]
European AGDS
PSS001289
[
  • 712 cases
  • , 3,650 controls
]
European AGDS
PSS001290
[
  • 582 cases
  • , 3,083 controls
]
European AGDS
PSS001291
[
  • 186 cases
  • , 1,800 controls
]
European AGDS
PSS001292
[
  • 235 cases
  • , 1,342 controls
]
European AGDS
PSS001293
[
  • 1,018 cases
  • , 4,695 controls
]
European AGDS
PSS001294
[
  • 793 cases
  • , 3,171 controls
]
European AGDS
PSS009252 4,057 individuals European Poland (NE Europe) UKB
PSS008358 6,001 individuals South Asian India (South Asia) UKB
PSS008742 898 individuals European Italy (South Europe) UKB
PSS011076 2,023 individuals,
37.4 % Male samples
Mean = 53.16 years
Sd = 16.23 years
African unspecified MGBB
PSS011076 932 individuals,
41.8 % Male samples
Mean = 47.0 years
Sd = 15.67 years
Asian unspecified MGBB
PSS011076 34,764 individuals,
46.7 % Male samples
Mean = 60.62 years
Sd = 16.83 years
European MGBB
PSS008747 6,626 individuals European Italy (South Europe) UKB
PSS011076 1,292 individuals,
46.8 % Male samples
Mean = 52.08 years
Sd = 18.42 years
Not reported MGBB
PSS007858 149 individuals African American or Afro-Caribbean Carribean UKB
PSS007863 2,460 individuals African American or Afro-Caribbean Carribean UKB
PSS011076 1,182 individuals,
31.3 % Male samples
Mean = 52.29 years
Sd = 16.56 years
Hispanic or Latin American MGBB
PSS009026 3,750 individuals African unspecified Nigeria (West Africa) UKB