Trait: dermatitis

Trait Information
Identifier MONDO_0002406
Description An inflammatory process affecting the skin. Signs include red rash, itching, and blister formation. Representative examples are contact dermatitis, atopic dermatitis, and seborrheic dermatitis. [NCIT: C2983]
Trait category
Other disease
Synonyms 6 synonyms
  • inflammation of skin
  • inflammation of the skin
  • inflammation of zone of skin
  • inflammatory skin disease
  • skin inflammation
  • zone of skin inflammation
Mapped terms 7 mapped terms
  • DOID:2723
  • ICD9:692.9
  • MEDGEN:849741
  • MESH:D003872
  • NCIT:C2983
  • SCTID:43116000
  • UMLS:C3875321
Child trait(s) 9 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "dermatitis" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000738
(CONFIRMED_PGS)
 PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
 Vitiligo vitiligo 48
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000738/ScoringFiles/PGS000738.txt.gz
PGS000760
(VIT)
 PGP000164 |
Khan Z et al. Nat Commun (2021)
 Vitiligo vitiligo 42
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000760/ScoringFiles/PGS000760.txt.gz
PGS000927
(GBE_HC1158)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Other dermatitis (time-to-event) dermatitis 242
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000927/ScoringFiles/PGS000927.txt.gz
PGS000944
(GBE_HC261)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Eczema, dermatitis Eczematoid dermatitis,
dermatitis		 598
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000944/ScoringFiles/PGS000944.txt.gz
PGS001312
(GBE_HC38)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Psoriasis psoriasis 204
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001312/ScoringFiles/PGS001312.txt.gz
PGS001313
(GBE_HC1159)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Psoriasis (time-to-event) psoriasis 578
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001313/ScoringFiles/PGS001313.txt.gz
PGS001536
(GBE_HC1188)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Vitiligo (time-to-event) vitiligo 77
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001536/ScoringFiles/PGS001536.txt.gz
PGS001773
(PRS_atopicDermatitis)
 PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
 Moderate-to-severe atopic dermatitis atopic eczema 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001773/ScoringFiles/PGS001773.txt.gz
PGS001871
(portability-PLR_696.4)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Psoriasis psoriasis 264
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001871/ScoringFiles/PGS001871.txt.gz
PGS002083
(portability-ldpred2_696.4)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Psoriasis psoriasis 71,744
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002083/ScoringFiles/PGS002083.txt.gz
PGS002293
(PRS62_psoriasis)
 PGP000323 |
Shen M et al. J Am Acad Dermatol (2022)
 Psoriasis psoriasis 62
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002293/ScoringFiles/PGS002293.txt.gz
PGS002344
(disease_PSORIASIS.BOLT-LMM)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 1,109,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002344/ScoringFiles/PGS002344.txt.gz
PGS002416
(disease_PSORIASIS.P+T.0.0001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 6,879
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002416/ScoringFiles/PGS002416.txt.gz
PGS002465
(disease_PSORIASIS.P+T.0.001)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 21,483
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002465/ScoringFiles/PGS002465.txt.gz
PGS002514
(disease_PSORIASIS.P+T.0.01)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 96,453
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002514/ScoringFiles/PGS002514.txt.gz
PGS002563
(disease_PSORIASIS.P+T.1e-06)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 1,348
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002563/ScoringFiles/PGS002563.txt.gz
PGS002612
(disease_PSORIASIS.P+T.5e-08)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 643
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002612/ScoringFiles/PGS002612.txt.gz
PGS002661
(disease_PSORIASIS.PolyFun-pred)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 283,128
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002661/ScoringFiles/PGS002661.txt.gz
PGS002710
(disease_PSORIASIS.SBayesR)
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Psoriasis psoriasis 566,839
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002710/ScoringFiles/PGS002710.txt.gz
PGS002755
(Atopic_dermatitis_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Atopic dermatitis atopic eczema 1,090,702
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002755/ScoringFiles/PGS002755.txt.gz
PGS003459
(PRS_CO)
 PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
 Atopic eczema or atopic disease atopic eczema,
allergic disease		 170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003459/ScoringFiles/PGS003459.txt.gz
PGS003486
(PRS_AE)
 PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
 Atopic eczema atopic eczema 71
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003486/ScoringFiles/PGS003486.txt.gz
PGS004260
(GenoBoost_psoriasis_0)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Psoriasis psoriasis 900
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004260/ScoringFiles/PGS004260.txt.gz
PGS004261
(GenoBoost_psoriasis_1)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Psoriasis psoriasis 800
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004261/ScoringFiles/PGS004261.txt.gz
PGS004262
(GenoBoost_psoriasis_2)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Psoriasis psoriasis 200
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004262/ScoringFiles/PGS004262.txt.gz
PGS004263
(GenoBoost_psoriasis_3)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Psoriasis psoriasis 800
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004263/ScoringFiles/PGS004263.txt.gz
PGS004264
(GenoBoost_psoriasis_4)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Psoriasis psoriasis 110
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004264/ScoringFiles/PGS004264.txt.gz
PGS004315
(GRS-ALL)
 PGP000547 |
Bui A et al. Front Genet (2023)
 Psoriasis psoriasis 88
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004315/ScoringFiles/PGS004315.txt.gz
PGS004316
(GRS-HLA)
 PGP000547 |
Bui A et al. Front Genet (2023)
 Psoriasis psoriasis 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004316/ScoringFiles/PGS004316.txt.gz
PGS004317
(GRS-noHLA)
 PGP000547 |
Bui A et al. Front Genet (2023)
 Psoriasis psoriasis 77
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004317/ScoringFiles/PGS004317.txt.gz
PGS004587
(PRS23_AD)
 PGP000566 |
Gu X et al. Ecotoxicol Environ Saf (2023)
 Atopic dermatitis atopic eczema 23
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004587/ScoringFiles/PGS004587.txt.gz
PGS004903
(PRS_ALL)
 PGP000633 |
Al-Janabi A et al. J Allergy Clin Immunol (2023)
 Atopic dermatitis atopic eczema 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004903/ScoringFiles/PGS004903.txt.gz
PGS005307
(GWS)
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Psoriasis psoriasis 64
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005307/ScoringFiles/PGS005307.txt.gz
PGS005308
(GWS-noHLA)
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Psoriasis psoriasis 64
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005308/ScoringFiles/PGS005308.txt.gz
PGS005309
(Full)
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Psoriasis psoriasis 513,461
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005309/ScoringFiles/PGS005309.txt.gz
PGS005310
(Full-noHLA)
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Psoriasis psoriasis 513,460
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005310/ScoringFiles/PGS005310.txt.gz
PGS005311
(Full_subset)
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Psoriasis psoriasis 487,311
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005311/ScoringFiles/PGS005311.txt.gz
PGS005312
(Full-noHLA_subset)
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Psoriasis psoriasis 487,310
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005312/ScoringFiles/PGS005312.txt.gz
PGS018445
(TPMI_110.11_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 39,561
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018445/ScoringFiles/PGS018445.txt.gz
PGS018446
(TPMI_110.11_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 350,151
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018446/ScoringFiles/PGS018446.txt.gz
PGS018447
(TPMI_110.11_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 16,307
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018447/ScoringFiles/PGS018447.txt.gz
PGS018448
(TPMI_110.11_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 983,814
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018448/ScoringFiles/PGS018448.txt.gz
PGS018449
(TPMI_110.11_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 977,859
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018449/ScoringFiles/PGS018449.txt.gz
PGS018450
(TPMI_110.13_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 54
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018450/ScoringFiles/PGS018450.txt.gz
PGS018451
(TPMI_110.13_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 939,803
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018451/ScoringFiles/PGS018451.txt.gz
PGS018452
(TPMI_110.13_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 605,197
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018452/ScoringFiles/PGS018452.txt.gz
PGS018453
(TPMI_110.13_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 983,765
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018453/ScoringFiles/PGS018453.txt.gz
PGS018454
(TPMI_110.13_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 1,012,332
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018454/ScoringFiles/PGS018454.txt.gz
PGS019605
(TPMI_696_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis and related disorders psoriasis 1,676
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019605/ScoringFiles/PGS019605.txt.gz
PGS019606
(TPMI_696_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis and related disorders psoriasis 334,427
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019606/ScoringFiles/PGS019606.txt.gz
PGS019607
(TPMI_696_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis and related disorders psoriasis 49,060
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019607/ScoringFiles/PGS019607.txt.gz
PGS019608
(TPMI_696_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis and related disorders psoriasis 983,757
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019608/ScoringFiles/PGS019608.txt.gz
PGS019609
(TPMI_696_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis and related disorders psoriasis 1,070,900
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019609/ScoringFiles/PGS019609.txt.gz
PGS019610
(TPMI_696_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis and related disorders psoriasis 68,664
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019610/ScoringFiles/PGS019610.txt.gz
PGS019611
(TPMI_696.4_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis psoriasis 1,717
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019611/ScoringFiles/PGS019611.txt.gz
PGS019612
(TPMI_696.4_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis psoriasis 939,806
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019612/ScoringFiles/PGS019612.txt.gz
PGS019613
(TPMI_696.4_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis psoriasis 49,115
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019613/ScoringFiles/PGS019613.txt.gz
PGS019614
(TPMI_696.4_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis psoriasis 983,757
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019614/ScoringFiles/PGS019614.txt.gz
PGS019615
(TPMI_696.4_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis psoriasis 1,071,406
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019615/ScoringFiles/PGS019615.txt.gz
PGS019616
(TPMI_696.4_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis psoriasis 61,542
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019616/ScoringFiles/PGS019616.txt.gz
PGS019617
(TPMI_696.41_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis vulgaris psoriasis vulgaris 1,357
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019617/ScoringFiles/PGS019617.txt.gz
PGS019618
(TPMI_696.41_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis vulgaris psoriasis vulgaris 330,044
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019618/ScoringFiles/PGS019618.txt.gz
PGS019619
(TPMI_696.41_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis vulgaris psoriasis vulgaris 49,531
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019619/ScoringFiles/PGS019619.txt.gz
PGS019620
(TPMI_696.41_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis vulgaris psoriasis vulgaris 983,756
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019620/ScoringFiles/PGS019620.txt.gz
PGS019621
(TPMI_696.41_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis vulgaris psoriasis vulgaris 1,071,390
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019621/ScoringFiles/PGS019621.txt.gz
PGS019622
(TPMI_696.41_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Psoriasis vulgaris psoriasis vulgaris 59,819
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019622/ScoringFiles/PGS019622.txt.gz
PGS019634
(TPMI_706.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 565,294
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019634/ScoringFiles/PGS019634.txt.gz
PGS019635
(TPMI_706.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 273,955
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019635/ScoringFiles/PGS019635.txt.gz
PGS019636
(TPMI_706.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 17,458
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019636/ScoringFiles/PGS019636.txt.gz
PGS019637
(TPMI_706.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 983,822
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019637/ScoringFiles/PGS019637.txt.gz
PGS019638
(TPMI_706.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Acne acne 961,798
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019638/ScoringFiles/PGS019638.txt.gz
PGS019778
(TPMI_939_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 109,945
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019778/ScoringFiles/PGS019778.txt.gz
PGS019779
(TPMI_939_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 939,881
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019779/ScoringFiles/PGS019779.txt.gz
PGS019780
(TPMI_939_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 453,270
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019780/ScoringFiles/PGS019780.txt.gz
PGS019781
(TPMI_939_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 983,816
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019781/ScoringFiles/PGS019781.txt.gz
PGS019782
(TPMI_939_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Atopic contact dermatitis due to other or unspecified contact dermatitis 928,454
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019782/ScoringFiles/PGS019782.txt.gz
PGS019783
(TPMI_947_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urticaria urticaria 806,711
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019783/ScoringFiles/PGS019783.txt.gz
PGS019784
(TPMI_947_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urticaria urticaria 939,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019784/ScoringFiles/PGS019784.txt.gz
PGS019785
(TPMI_947_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urticaria urticaria 40,435
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019785/ScoringFiles/PGS019785.txt.gz
PGS019786
(TPMI_947_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urticaria urticaria 983,749
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019786/ScoringFiles/PGS019786.txt.gz
PGS019787
(TPMI_947_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Urticaria urticaria 973,975
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019787/ScoringFiles/PGS019787.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM001761 PGS000738
(CONFIRMED_PGS)
 PSS000907|
European Ancestry|
4,008 individuals
 PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
 Reported Trait: Vitiligo — — Odds Ratio (OR, top 20% vs remaining 80% of score distribution): 4.87 [4.21, 5.64] — —
PPM001762 PGS000738
(CONFIRMED_PGS)
 PSS000907|
European Ancestry|
4,008 individuals
 PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
 Reported Trait: Vitiligo — — Odds Ratio (OR, top 10% vs remaining 90% of score distribution): 5.26 [4.42, 6.29] — —
PPM001763 PGS000738
(CONFIRMED_PGS)
 PSS000907|
European Ancestry|
4,008 individuals
 PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
 Reported Trait: Vitiligo — — Odds Ratio (OR, top 10% vs remaining 95% of score distribution): 6.2 [4.96, 7.79] — —
PPM001764 PGS000738
(CONFIRMED_PGS)
 PSS000907|
European Ancestry|
4,008 individuals
 PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
 Reported Trait: Vitiligo — — Odds Ratio (OR, top 1% vs remaining 99% of score distribution): 8.79 [5.85, 13.78] — —
PPM018437 PGS000738
(CONFIRMED_PGS)
 PSS010969|
European Ancestry|
4,945 individuals
 PGP000467 |
Farré X et al. Genes (Basel) (2023)
|Ext.		 Reported Trait: Fitzpatrick scale β: 0.02234 — R²: 0.02897 — —
PPM018438 PGS000738
(CONFIRMED_PGS)
 PSS010968|
European Ancestry|
4,702 individuals
 PGP000467 |
Farré X et al. Genes (Basel) (2023)
|Ext.		 Reported Trait: Red hair β: 0.69478 — pseudo R²: 0.03857 — —
PPM018435 PGS000738
(CONFIRMED_PGS)
 PSS010977|
European Ancestry|
4,987 individuals
 PGP000467 |
Farré X et al. Genes (Basel) (2023)
|Ext.		 Reported Trait: Freckles β: -0.04382 — R²: 0.02103 — —
PPM018436 PGS000738
(CONFIRMED_PGS)
 PSS010974|
European Ancestry|
4,979 individuals
 PGP000467 |
Farré X et al. Genes (Basel) (2023)
|Ext.		 Reported Trait: Phototype score β: 0.4039 — R²: 0.03252 — —
PPM001935 PGS000760
(VIT)
 PSS000970|
European Ancestry|
1,584 individuals
 PGP000164 |
Khan Z et al. Nat Commun (2021)
 Reported Trait: anti-PD-L1 induced hypothyroidism in cancer patients HR: 1.41 [1.22, 1.61] — meta-analysis p-value: 1.10e-06 5 genotype PCs —
PPM007462 PGS000927
(GBE_HC1158)
 PSS004153|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other dermatitis — AUROC: 0.61027 [0.57953, 0.64101] R²: 0.02035
Incremental AUROC (full-covars): 0.00207
PGS R2 (no covariates): 0.00268
PGS AUROC (no covariates): 0.5378 [0.50673, 0.56886]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007463 PGS000927
(GBE_HC1158)
 PSS004154|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other dermatitis — AUROC: 0.57706 [0.52927, 0.62486] R²: 0.02951
Incremental AUROC (full-covars): 0.01147
PGS R2 (no covariates): 0.00458
PGS AUROC (no covariates): 0.5429 [0.49389, 0.59191]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007464 PGS000927
(GBE_HC1158)
 PSS004155|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other dermatitis — AUROC: 0.54587 [0.53304, 0.5587] R²: 0.00506
Incremental AUROC (full-covars): 0.01785
PGS R2 (no covariates): 0.00339
PGS AUROC (no covariates): 0.53939 [0.52639, 0.55239]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007465 PGS000927
(GBE_HC1158)
 PSS004156|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other dermatitis — AUROC: 0.58261 [0.56273, 0.60248] R²: 0.01573
Incremental AUROC (full-covars): 0.00482
PGS R2 (no covariates): 0.00187
PGS AUROC (no covariates): 0.52627 [0.50591, 0.54663]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007466 PGS000927
(GBE_HC1158)
 PSS004157|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other dermatitis — AUROC: 0.56752 [0.56014, 0.57491] R²: 0.01047
Incremental AUROC (full-covars): 0.01697
PGS R2 (no covariates): 0.00542
PGS AUROC (no covariates): 0.54889 [0.54154, 0.55624]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007546 PGS000944
(GBE_HC261)
 PSS004384|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Eczema/dermatitis — AUROC: 0.62856 [0.58377, 0.67334] R²: 0.02337
Incremental AUROC (full-covars): 0.00187
PGS R2 (no covariates): 0.00173
PGS AUROC (no covariates): 0.52778 [0.48039, 0.57516]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007547 PGS000944
(GBE_HC261)
 PSS004385|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Eczema/dermatitis — AUROC: 0.59588 [0.52553, 0.66622] R²: 0.02855
Incremental AUROC (full-covars): 0.02432
PGS R2 (no covariates): 0.0116
PGS AUROC (no covariates): 0.58664 [0.52213, 0.65115]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007548 PGS000944
(GBE_HC261)
 PSS004386|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Eczema/dermatitis — AUROC: 0.56459 [0.54541, 0.58377] R²: 0.00802
Incremental AUROC (full-covars): 0.01208
PGS R2 (no covariates): 0.00353
PGS AUROC (no covariates): 0.54597 [0.52632, 0.56561]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007549 PGS000944
(GBE_HC261)
 PSS004387|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Eczema/dermatitis — AUROC: 0.56106 [0.52439, 0.59773] R²: 0.00683
Incremental AUROC (full-covars): -0.0012
PGS R2 (no covariates): 0.00011
PGS AUROC (no covariates): 0.51686 [0.48122, 0.5525]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007550 PGS000944
(GBE_HC261)
 PSS004388|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Eczema/dermatitis — AUROC: 0.57099 [0.55943, 0.58256] R²: 0.00884
Incremental AUROC (full-covars): 0.02521
PGS R2 (no covariates): 0.00527
PGS AUROC (no covariates): 0.5556 [0.54396, 0.56724]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009053 PGS001312
(GBE_HC38)
 PSS004471|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriasis — AUROC: 0.73107 [0.60624, 0.85591] R²: 0.06593
Incremental AUROC (full-covars): 0.0282
PGS R2 (no covariates): 0.01927
PGS AUROC (no covariates): 0.62557 [0.48848, 0.76266]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009054 PGS001312
(GBE_HC38)
 PSS004472|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriasis — AUROC: 0.88867 [0.80531, 0.97202] R²: 0.24575
Incremental AUROC (full-covars): 0.01187
PGS R2 (no covariates): 0.00399
PGS AUROC (no covariates): 0.57774 [0.40533, 0.75016]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009055 PGS001312
(GBE_HC38)
 PSS004473|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriasis — AUROC: 0.68424 [0.65757, 0.71091] R²: 0.05057
Incremental AUROC (full-covars): 0.0981
PGS R2 (no covariates): 0.04137
PGS AUROC (no covariates): 0.66409 [0.63596, 0.69222]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009056 PGS001312
(GBE_HC38)
 PSS004474|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriasis — AUROC: 0.6849 [0.63397, 0.73584] R²: 0.0448
Incremental AUROC (full-covars): 0.052
PGS R2 (no covariates): 0.02087
PGS AUROC (no covariates): 0.64825 [0.59861, 0.6979]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009057 PGS001312
(GBE_HC38)
 PSS004475|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriasis — AUROC: 0.69754 [0.68165, 0.71343] R²: 0.05574
Incremental AUROC (full-covars): 0.14505
PGS R2 (no covariates): 0.05226
PGS AUROC (no covariates): 0.69158 [0.6754, 0.70775]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009058 PGS001313
(GBE_HC1159)
 PSS004158|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE psoriasis — AUROC: 0.69906 [0.60273, 0.7954] R²: 0.04185
Incremental AUROC (full-covars): 0.01899
PGS R2 (no covariates): 0.00732
PGS AUROC (no covariates): 0.62223 [0.54291, 0.70154]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009059 PGS001313
(GBE_HC1159)
 PSS004159|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE psoriasis — AUROC: 0.72306 [0.61623, 0.82989] R²: 0.09162
Incremental AUROC (full-covars): 0.00222
PGS R2 (no covariates): 0.00378
PGS AUROC (no covariates): 0.48492 [0.37014, 0.5997]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009060 PGS001313
(GBE_HC1159)
 PSS004160|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE psoriasis — AUROC: 0.66545 [0.64532, 0.68558] R²: 0.04468
Incremental AUROC (full-covars): 0.07449
PGS R2 (no covariates): 0.0337
PGS AUROC (no covariates): 0.64565 [0.62471, 0.66658]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009061 PGS001313
(GBE_HC1159)
 PSS004161|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE psoriasis — AUROC: 0.63418 [0.59417, 0.67419] R²: 0.0236
Incremental AUROC (full-covars): 0.05154
PGS R2 (no covariates): 0.0123
PGS AUROC (no covariates): 0.60455 [0.56482, 0.64428]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009062 PGS001313
(GBE_HC1159)
 PSS004162|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE psoriasis — AUROC: 0.67543 [0.66285, 0.68801] R²: 0.05117
Incremental AUROC (full-covars): 0.13853
PGS R2 (no covariates): 0.04966
PGS AUROC (no covariates): 0.6729 [0.66027, 0.68553]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005215 PGS001536
(GBE_HC1188)
 PSS004173|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vitiligo — AUROC: 0.63509 [0.52563, 0.74454] R²: 0.01654
Incremental AUROC (full-covars): -0.00281
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.51169 [0.39527, 0.62811]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005216 PGS001536
(GBE_HC1188)
 PSS004174|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vitiligo — AUROC: 0.82774 [0.75298, 0.90249] R²: 0.08055
Incremental AUROC (full-covars): 0.01924
PGS R2 (no covariates): 0.00431
PGS AUROC (no covariates): 0.57823 [0.37976, 0.7767]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005217 PGS001536
(GBE_HC1188)
 PSS004175|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vitiligo — AUROC: 0.6991 [0.61917, 0.77902] R²: 0.03993
Incremental AUROC (full-covars): 0.01341
PGS R2 (no covariates): 0.00254
PGS AUROC (no covariates): 0.55625 [0.47549, 0.63701]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005218 PGS001536
(GBE_HC1188)
 PSS004176|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vitiligo — AUROC: 0.64566 [0.58746, 0.70386] R²: 0.02575
Incremental AUROC (full-covars): 0.0309
PGS R2 (no covariates): 0.01048
PGS AUROC (no covariates): 0.60302 [0.5391, 0.66694]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005219 PGS001536
(GBE_HC1188)
 PSS004177|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vitiligo — AUROC: 0.63449 [0.58754, 0.68144] R²: 0.01686
Incremental AUROC (full-covars): 0.08163
PGS R2 (no covariates): 0.01621
PGS AUROC (no covariates): 0.64193 [0.59907, 0.68478]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009229 PGS001773
(PRS_atopicDermatitis)
 PSS007661|
Multi-ancestry (including European)|
676 individuals
 PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
 Reported Trait: Moderate-to-severe aotpic dermatitis — AUROC: 0.93 R²: 0.49 Age, sex, father's ethnicity, mother ethnicity Nagelkerke's R^2, only unrelated individuals were considered in the analyses
PPM009230 PGS001773
(PRS_atopicDermatitis)
 PSS007661|
Multi-ancestry (including European)|
676 individuals
 PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
 Reported Trait: Food allergy — AUROC: 0.75 — Age, sex, father's ethnicity, mother ethnicity Only unrelated individuals were considered in the analyses
PPM009231 PGS001773
(PRS_atopicDermatitis)
 PSS007661|
Multi-ancestry (including European)|
676 individuals
 PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
 Reported Trait: Allergic asthma — AUROC: 0.75 — Age, sex, father's ethnicity, mother ethnicity Only unrelated individuals were considered in the analyses
PPM009232 PGS001773
(PRS_atopicDermatitis)
 PSS007661|
Multi-ancestry (including European)|
676 individuals
 PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
 Reported Trait: Allergic rhinitis — AUROC: 0.77 — Age, sex, father's ethnicity, mother ethnicity Only unrelated individuals were considered in the analyses
PPM009857 PGS001871
(portability-PLR_696.4)
 PSS009347|
European Ancestry|
19,615 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0636 [0.0497, 0.0775] sex, age, birth date, deprivation index, 16 PCs —
PPM009858 PGS001871
(portability-PLR_696.4)
 PSS009121|
European Ancestry|
4,059 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.107 [0.0764, 0.1374] sex, age, birth date, deprivation index, 16 PCs —
PPM009859 PGS001871
(portability-PLR_696.4)
 PSS008675|
European Ancestry|
6,554 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0404 [0.0162, 0.0646] sex, age, birth date, deprivation index, 16 PCs —
PPM009860 PGS001871
(portability-PLR_696.4)
 PSS008449|
Greater Middle Eastern Ancestry|
1,183 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0463 [-0.0112, 0.1035] sex, age, birth date, deprivation index, 16 PCs —
PPM009861 PGS001871
(portability-PLR_696.4)
 PSS008229|
South Asian Ancestry|
6,161 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0327 [0.0077, 0.0577] sex, age, birth date, deprivation index, 16 PCs —
PPM009862 PGS001871
(portability-PLR_696.4)
 PSS008010|
East Asian Ancestry|
1,784 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0079 [-0.0388, 0.0545] sex, age, birth date, deprivation index, 16 PCs —
PPM009863 PGS001871
(portability-PLR_696.4)
 PSS007794|
African Ancestry|
2,398 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0357 [-0.0045, 0.0757] sex, age, birth date, deprivation index, 16 PCs —
PPM009864 PGS001871
(portability-PLR_696.4)
 PSS008898|
African Ancestry|
3,834 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): -0.0065 [-0.0382, 0.0252] sex, age, birth date, deprivation index, 16 PCs —
PPM011525 PGS002083
(portability-ldpred2_696.4)
 PSS009347|
European Ancestry|
19,615 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0632 [0.0493, 0.0771] sex, age, birth date, deprivation index, 16 PCs —
PPM011526 PGS002083
(portability-ldpred2_696.4)
 PSS009121|
European Ancestry|
4,059 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.1153 [0.0847, 0.1456] sex, age, birth date, deprivation index, 16 PCs —
PPM011527 PGS002083
(portability-ldpred2_696.4)
 PSS008675|
European Ancestry|
6,554 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.041 [0.0168, 0.0652] sex, age, birth date, deprivation index, 16 PCs —
PPM011529 PGS002083
(portability-ldpred2_696.4)
 PSS008229|
South Asian Ancestry|
6,161 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.03 [0.005, 0.055] sex, age, birth date, deprivation index, 16 PCs —
PPM011530 PGS002083
(portability-ldpred2_696.4)
 PSS008010|
East Asian Ancestry|
1,784 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0119 [-0.0348, 0.0585] sex, age, birth date, deprivation index, 16 PCs —
PPM011531 PGS002083
(portability-ldpred2_696.4)
 PSS007794|
African Ancestry|
2,398 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0375 [-0.0027, 0.0776] sex, age, birth date, deprivation index, 16 PCs —
PPM011532 PGS002083
(portability-ldpred2_696.4)
 PSS008898|
African Ancestry|
3,834 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): -0.0166 [-0.0483, 0.0152] sex, age, birth date, deprivation index, 16 PCs —
PPM011528 PGS002083
(portability-ldpred2_696.4)
 PSS008449|
Greater Middle Eastern Ancestry|
1,183 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Psoriasis — — Partial Correlation (partial-r): 0.0458 [-0.0117, 0.1031] sex, age, birth date, deprivation index, 16 PCs —
PPM013020 PGS002293
(PRS62_psoriasis)
 PSS009651|
European Ancestry|
345,672 individuals
 PGP000323 |
Shen M et al. J Am Acad Dermatol (2022)
 Reported Trait: Incident psoriasis HR: 4.625 [2.92, 7.348] — Odds Ratio (OR, poor lifestyle and high genetic risk): 4.625 [2.92, 7.348]
Population-attributable fraction of genetic risk: 0.13 [0.032, 0.218]		 Age, sex, education, Townsend Index, and region, relatedness, number of alleles included in the polygenic risk score, and first 20 principal components of ancestry —
PPM013109 PGS002344
(disease_PSORIASIS.BOLT-LMM)
 PSS009819|
African Ancestry|
6,503 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013158 PGS002344
(disease_PSORIASIS.BOLT-LMM)
 PSS009820|
East Asian Ancestry|
922 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013207 PGS002344
(disease_PSORIASIS.BOLT-LMM)
 PSS009821|
European Ancestry|
43,505 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.007 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013256 PGS002344
(disease_PSORIASIS.BOLT-LMM)
 PSS009822|
South Asian Ancestry|
8,098 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0035 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013397 PGS002416
(disease_PSORIASIS.P+T.0.0001)
 PSS009819|
African Ancestry|
6,503 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0005 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013446 PGS002416
(disease_PSORIASIS.P+T.0.0001)
 PSS009820|
East Asian Ancestry|
922 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013495 PGS002416
(disease_PSORIASIS.P+T.0.0001)
 PSS009821|
European Ancestry|
43,505 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013544 PGS002416
(disease_PSORIASIS.P+T.0.0001)
 PSS009822|
South Asian Ancestry|
8,098 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013593 PGS002465
(disease_PSORIASIS.P+T.0.001)
 PSS009819|
African Ancestry|
6,503 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0003 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013642 PGS002465
(disease_PSORIASIS.P+T.0.001)
 PSS009820|
East Asian Ancestry|
922 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013691 PGS002465
(disease_PSORIASIS.P+T.0.001)
 PSS009821|
European Ancestry|
43,505 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013740 PGS002465
(disease_PSORIASIS.P+T.0.001)
 PSS009822|
South Asian Ancestry|
8,098 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013789 PGS002514
(disease_PSORIASIS.P+T.0.01)
 PSS009819|
African Ancestry|
6,503 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0003 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013838 PGS002514
(disease_PSORIASIS.P+T.0.01)
 PSS009820|
East Asian Ancestry|
922 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013887 PGS002514
(disease_PSORIASIS.P+T.0.01)
 PSS009821|
European Ancestry|
43,505 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013936 PGS002514
(disease_PSORIASIS.P+T.0.01)
 PSS009822|
South Asian Ancestry|
8,098 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013985 PGS002563
(disease_PSORIASIS.P+T.1e-06)
 PSS009819|
African Ancestry|
6,503 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0004 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014034 PGS002563
(disease_PSORIASIS.P+T.1e-06)
 PSS009820|
East Asian Ancestry|
922 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014083 PGS002563
(disease_PSORIASIS.P+T.1e-06)
 PSS009821|
European Ancestry|
43,505 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014132 PGS002563
(disease_PSORIASIS.P+T.1e-06)
 PSS009822|
South Asian Ancestry|
8,098 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014181 PGS002612
(disease_PSORIASIS.P+T.5e-08)
 PSS009819|
African Ancestry|
6,503 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0007 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014230 PGS002612
(disease_PSORIASIS.P+T.5e-08)
 PSS009820|
East Asian Ancestry|
922 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014279 PGS002612
(disease_PSORIASIS.P+T.5e-08)
 PSS009821|
European Ancestry|
43,505 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014328 PGS002612
(disease_PSORIASIS.P+T.5e-08)
 PSS009822|
South Asian Ancestry|
8,098 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014377 PGS002661
(disease_PSORIASIS.PolyFun-pred)
 PSS009819|
African Ancestry|
6,503 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014426 PGS002661
(disease_PSORIASIS.PolyFun-pred)
 PSS009820|
East Asian Ancestry|
922 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014475 PGS002661
(disease_PSORIASIS.PolyFun-pred)
 PSS009821|
European Ancestry|
43,505 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.007 age, sex, age*sex, assessment center, genotyping array, 10 PCs See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014524 PGS002661
(disease_PSORIASIS.PolyFun-pred)
 PSS009822|
South Asian Ancestry|
8,098 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0034 age, sex, age*sex, assessment center, genotyping array, 10 PCs See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014622 PGS002710
(disease_PSORIASIS.SBayesR)
 PSS009820|
East Asian Ancestry|
922 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014671 PGS002710
(disease_PSORIASIS.SBayesR)
 PSS009821|
European Ancestry|
43,505 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0014 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014720 PGS002710
(disease_PSORIASIS.SBayesR)
 PSS009822|
South Asian Ancestry|
8,098 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.002 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014573 PGS002710
(disease_PSORIASIS.SBayesR)
 PSS009819|
African Ancestry|
6,503 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Psoriasis — — Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM014955 PGS002755
(Atopic_dermatitis_prscs)
 PSS009939|
European Ancestry|
39,444 individuals
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Reported Trait: Atopic dermatitis OR: 1.28 [1.21, 1.34] — — age, sex, 10 PCs, technical covariates —
PPM020709 PGS002755
(Atopic_dermatitis_prscs)
 PSS011376|
European Ancestry|
337,910 individuals
 PGP000566 |
Gu X et al. Ecotoxicol Environ Saf (2023)
|Ext.		 Reported Trait: Incident atopic dermatitis — — Hazard ratio (HR, high vs low PRS): 1.249 [1.123, 1.391] sex, age, Townsend index, moderate physical and household income —
PPM020710 PGS002755
(Atopic_dermatitis_prscs)
 PSS011376|
European Ancestry|
337,910 individuals
 PGP000566 |
Gu X et al. Ecotoxicol Environ Saf (2023)
|Ext.		 Reported Trait: Incident atopic dermatitis with air pollution level — — Hazard ratio (HR, high air pollution and high PRS vs low air pollution and low PRS): 1.978 [1.624, 2.411] sex, age, Townsend index, moderate physical and household income —
PPM017414 PGS003459
(PRS_CO)
 PSS010186|
European Ancestry|
3,212 individuals
 PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
 Reported Trait: Paradoxical eczema in biologic-treated psoriasis OR: 1.83 [1.17, 2.84] AUROC: 0.585 — PCs 1-2 —
PPM017412 PGS003486
(PRS_AE)
 PSS010186|
European Ancestry|
3,212 individuals
 PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
 Reported Trait: Paradoxical eczema in biologic-treated psoriasis OR: 1.89 [1.08, 3.3] AUROC: 0.567 — PCs 1-2 —
PPM020328 PGS004260
(GenoBoost_psoriasis_0)
 PSS011347|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Psoriasis — AUROC: 0.66908 Covariate-adjusted pseudo-R2: 0.04239
AUPRC: 0.04468		 age, sex, PC1-10 —
PPM020329 PGS004261
(GenoBoost_psoriasis_1)
 PSS011347|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Psoriasis — AUROC: 0.67722 Covariate-adjusted pseudo-R2: 0.04563
AUPRC: 0.0457		 age, sex, PC1-10 —
PPM020330 PGS004262
(GenoBoost_psoriasis_2)
 PSS011347|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Psoriasis — AUROC: 0.66916 Covariate-adjusted pseudo-R2: 0.04211
AUPRC: 0.0431		 age, sex, PC1-10 —
PPM020331 PGS004263
(GenoBoost_psoriasis_3)
 PSS011347|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Psoriasis — AUROC: 0.67205 Covariate-adjusted pseudo-R2: 0.04423
AUPRC: 0.04681		 age, sex, PC1-10 —
PPM020332 PGS004264
(GenoBoost_psoriasis_4)
 PSS011347|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Psoriasis — AUROC: 0.66842 Covariate-adjusted pseudo-R2: 0.04356
AUPRC: 0.04551		 age, sex, PC1-10 —
PPM020383 PGS004315
(GRS-ALL)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Family history of psoriasis OR: 1.02 [1.0, 1.04] — R²: 0.0067 — —
PPM020384 PGS004315
(GRS-ALL)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Age of psoriasis onset OR: 0.71 [0.59, 0.85] — R²: 0.023 — —
PPM020386 PGS004315
(GRS-ALL)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Age of type1 psoriasis onset OR: 0.82 [0.59, 0.85] — R²: 0.0206 — —
PPM020388 PGS004315
(GRS-ALL)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Psoriasis severity OR: 1.02 [1.0, 1.06] — R²: 0.061 — —
PPM020390 PGS004315
(GRS-ALL)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Total number of locations ever affected by psoriasis OR: 1.16 [1.11, 1.21] — R²: 0.061 — —
PPM020393 PGS004315
(GRS-ALL)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Initial presentation of psoriasis at elbow or knee OR: 0.97 [0.94, 0.99] — — — —
PPM020396 PGS004315
(GRS-ALL)
 PSS011348|
European Ancestry|
345 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Psoriasis in genital area β: -0.037 (0.016) — — — —
PPM020385 PGS004316
(GRS-HLA)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Age of psoriasis onset OR: 0.46 [0.34, 0.63] — R²: 0.0398 — —
PPM020387 PGS004316
(GRS-HLA)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Age of type1 psoriasis onset OR: 0.69 [0.56, 0.86] — R²: 0.0216 — —
PPM020389 PGS004316
(GRS-HLA)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Psoriasis severity OR: 1.09 [1.03, 1.15] — R²: 0.077 — —
PPM020391 PGS004316
(GRS-HLA)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Total number of locations ever affected by psoriasis OR: 1.34 [1.24, 1.45] — R²: 0.077 — —
PPM020394 PGS004316
(GRS-HLA)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Initial presentation of psoriasis at elbow or knee OR: 0.92 [0.88, 0.96] — — — —
PPM020392 PGS004317
(GRS-noHLA)
 PSS011349|
European Ancestry|
654 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Psoriasis in genital area OR: 0.97 [0.94, 1.0] — — — —
PPM020395 PGS004317
(GRS-noHLA)
 PSS011348|
European Ancestry|
345 individuals
 PGP000547 |
Bui A et al. Front Genet (2023)
 Reported Trait: Psoriasis in genital area β: -0.038 (0.019) — — — —
PPM020707 PGS004587
(PRS23_AD)
 PSS011376|
European Ancestry|
337,910 individuals
 PGP000566 |
Gu X et al. Ecotoxicol Environ Saf (2023)
 Reported Trait: Incident atopic dermatitis — — Hazard ratio (HR, high vs low PRS): 1.153 [1.037, 1.282] sex, age, Townsend index, moderate physical and household income —
PPM020708 PGS004587
(PRS23_AD)
 PSS011376|
European Ancestry|
337,910 individuals
 PGP000566 |
Gu X et al. Ecotoxicol Environ Saf (2023)
 Reported Trait: Incident atopic dermatitis with air pollution level — — Hazard ratio (HR, high air pollution and high PRS vs low air pollution and low PRS): 1.523 [1.259, 1.84] sex, age, Townsend index, moderate physical and household income —
PPM021335 PGS004903
(PRS_ALL)
 PSS011691|
European Ancestry|
3,212 individuals
 PGP000633 |
Al-Janabi A et al. J Allergy Clin Immunol (2023)
 Reported Trait: Paradoxical eczema in individuals with psoriasis — — Coefficient: 4.77 [0.58, 8.96]
p: 0.026		 — —
PPM023015 PGS005307
(GWS)
 PSS012098|
European Ancestry|
9,426 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.19 [1.12, 1.26] — — — —
PPM023019 PGS005307
(GWS)
 PSS012094|
European Ancestry|
14,167 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.44 [1.36, 1.51] — — — —
PPM023023 PGS005307
(GWS)
 PSS012096|
European Ancestry|
8,603 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.26 [1.19, 1.33] — — — —
PPM023027 PGS005307
(GWS)
 PSS012095|
European Ancestry|
12,708 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.22 [1.17, 1.26] — — — —
PPM023016 PGS005308
(GWS-noHLA)
 PSS012098|
European Ancestry|
9,426 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.22 [1.15, 1.3] — — — —
PPM023020 PGS005308
(GWS-noHLA)
 PSS012094|
European Ancestry|
14,167 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.25 [1.18, 1.31] — — — —
PPM023024 PGS005308
(GWS-noHLA)
 PSS012096|
European Ancestry|
8,603 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.23 [1.17, 1.31] — — — —
PPM023028 PGS005308
(GWS-noHLA)
 PSS012095|
European Ancestry|
12,708 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.19 [1.15, 1.24] — — — —
PPM023017 PGS005309
(Full)
 PSS012098|
European Ancestry|
9,426 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.33 [1.25, 1.41] — — — —
PPM023021 PGS005309
(Full)
 PSS012094|
European Ancestry|
14,167 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.49 [1.41, 1.57] — — — —
PPM023025 PGS005309
(Full)
 PSS012096|
European Ancestry|
8,603 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.29 [1.22, 1.36] — — — —
PPM023029 PGS005309
(Full)
 PSS012095|
European Ancestry|
12,708 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.23 [1.18, 1.27] — — — —
PPM023018 PGS005310
(Full-noHLA)
 PSS012098|
European Ancestry|
9,426 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.4 [1.32, 1.49] — — — —
PPM023022 PGS005310
(Full-noHLA)
 PSS012094|
European Ancestry|
14,167 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.38 [1.31, 1.45] — — — —
PPM023026 PGS005310
(Full-noHLA)
 PSS012096|
European Ancestry|
8,603 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.25 [1.19, 1.33] — — — —
PPM023030 PGS005310
(Full-noHLA)
 PSS012095|
European Ancestry|
12,708 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis OR: 1.23 [1.18, 1.28] — — — —
PPM023031 PGS005311
(Full_subset)
 PSS012093|
European Ancestry|
13,577 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis (BSTOP) vs. any psoriasis (UKB) — — Percentage of cases with risk >95th percentile of UKB psoraisis cases: 15.3 — —
PPM023033 PGS005311
(Full_subset)
 PSS012097|
European Ancestry|
10,887 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis (Novartis) vs. any psoriasis (UKB) — — Percentage of cases with risk >95th percentile of UKB psoraisis cases: 11.6 — —
PPM023032 PGS005312
(Full-noHLA_subset)
 PSS012093|
European Ancestry|
13,577 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis (BSTOP) vs. any psoriasis (UKB) — — Percentage of cases with risk >95th percentile of UKB psoraisis cases: 15.3 — —
PPM023034 PGS005312
(Full-noHLA_subset)
 PSS012097|
European Ancestry|
10,887 individuals
 PGP000760 |
Saklatvala JR et al. Genome Med (2025)
 Reported Trait: Severe psoriasis (Novartis) vs. any psoriasis (UKB) — — Percentage of cases with risk >95th percentile of UKB psoraisis cases: 11.5 — —
PPM036627 PGS018445
(TPMI_110.11_Lassosum2)
 PSS012348|
East Asian Ancestry|
18,675 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of nail — AUROC: 0.64442 R²: 0.03556 sex, age, array, PCs 1-10 —
PPM036628 PGS018446
(TPMI_110.11_LDpred2)
 PSS012347|
East Asian Ancestry|
18,675 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of nail — AUROC: 0.64093 R²: 0.03399 sex, age, array, PCs 1-10 —
PPM036629 PGS018447
(TPMI_110.11_MegaPRS)
 PSS012349|
East Asian Ancestry|
18,675 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of nail — AUROC: 0.63748 R²: 0.03245 sex, age, array, PCs 1-10 —
PPM036630 PGS018448
(TPMI_110.11_PRS-CS)
 PSS012350|
East Asian Ancestry|
18,675 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of nail — AUROC: 0.64402 R²: 0.03487 sex, age, array, PCs 1-10 —
PPM036631 PGS018449
(TPMI_110.11_SBayesR)
 PSS012351|
East Asian Ancestry|
18,675 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of nail — AUROC: 0.64206 R²: 0.03373 sex, age, array, PCs 1-10 —
PPM036632 PGS018450
(TPMI_110.13_Lassosum2)
 PSS012353|
East Asian Ancestry|
18,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of the body — AUROC: 0.66227 R²: 0.01587 sex, age, array, PCs 1-10 —
PPM036633 PGS018451
(TPMI_110.13_LDpred2)
 PSS012352|
East Asian Ancestry|
18,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of the body — AUROC: 0.66275 R²: 0.01528 sex, age, array, PCs 1-10 —
PPM036634 PGS018452
(TPMI_110.13_MegaPRS)
 PSS012354|
East Asian Ancestry|
18,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of the body — AUROC: 0.66222 R²: 0.01529 sex, age, array, PCs 1-10 —
PPM036635 PGS018453
(TPMI_110.13_PRS-CS)
 PSS012355|
East Asian Ancestry|
18,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of the body — AUROC: 0.66296 R²: 0.01529 sex, age, array, PCs 1-10 —
PPM036636 PGS018454
(TPMI_110.13_SBayesR)
 PSS012356|
East Asian Ancestry|
18,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Dermatophytosis of the body — AUROC: 0.66265 R²: 0.01527 sex, age, array, PCs 1-10 —
PPM037787 PGS019605
(TPMI_696_Lassosum2)
 PSS013526|
East Asian Ancestry|
17,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis and related disorders — AUROC: 0.7941 R²: 0.08516 sex, age, array, PCs 1-10 —
PPM037788 PGS019606
(TPMI_696_LDpred2)
 PSS013525|
East Asian Ancestry|
17,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis and related disorders — AUROC: 0.79605 R²: 0.08705 sex, age, array, PCs 1-10 —
PPM037789 PGS019607
(TPMI_696_MegaPRS)
 PSS013527|
East Asian Ancestry|
17,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis and related disorders — AUROC: 0.76905 R²: 0.06926 sex, age, array, PCs 1-10 —
PPM037790 PGS019608
(TPMI_696_PRS-CS)
 PSS013528|
East Asian Ancestry|
17,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis and related disorders — AUROC: 0.786 R²: 0.08181 sex, age, array, PCs 1-10 —
PPM037791 PGS019609
(TPMI_696_PRSmix+)
 PSS013529|
East Asian Ancestry|
17,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis and related disorders — AUROC: 0.80922 R²: 0.09389 sex, age, array, PCs 1-10 —
PPM037792 PGS019610
(TPMI_696_SBayesR)
 PSS013530|
East Asian Ancestry|
17,380 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis and related disorders — AUROC: 0.78953 R²: 0.08194 sex, age, array, PCs 1-10 —
PPM037793 PGS019611
(TPMI_696.4_Lassosum2)
 PSS013520|
East Asian Ancestry|
17,370 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis — AUROC: 0.79825 R²: 0.07798 sex, age, array, PCs 1-10 —
PPM037794 PGS019612
(TPMI_696.4_LDpred2)
 PSS013519|
East Asian Ancestry|
17,370 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis — AUROC: 0.80085 R²: 0.07986 sex, age, array, PCs 1-10 —
PPM037795 PGS019613
(TPMI_696.4_MegaPRS)
 PSS013521|
East Asian Ancestry|
17,370 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis — AUROC: 0.77026 R²: 0.06248 sex, age, array, PCs 1-10 —
PPM037796 PGS019614
(TPMI_696.4_PRS-CS)
 PSS013522|
East Asian Ancestry|
17,370 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis — AUROC: 0.79208 R²: 0.07383 sex, age, array, PCs 1-10 —
PPM037797 PGS019615
(TPMI_696.4_PRSmix+)
 PSS013523|
East Asian Ancestry|
17,370 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis — AUROC: 0.81274 R²: 0.08633 sex, age, array, PCs 1-10 —
PPM037798 PGS019616
(TPMI_696.4_SBayesR)
 PSS013524|
East Asian Ancestry|
17,370 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis — AUROC: 0.79236 R²: 0.07441 sex, age, array, PCs 1-10 —
PPM037799 PGS019617
(TPMI_696.41_Lassosum2)
 PSS013508|
East Asian Ancestry|
17,325 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis vulgaris — AUROC: 0.81124 R²: 0.072 sex, age, array, PCs 1-10 —
PPM037800 PGS019618
(TPMI_696.41_LDpred2)
 PSS013507|
East Asian Ancestry|
17,325 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis vulgaris — AUROC: 0.81009 R²: 0.07253 sex, age, array, PCs 1-10 —
PPM037801 PGS019619
(TPMI_696.41_MegaPRS)
 PSS013509|
East Asian Ancestry|
17,325 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis vulgaris — AUROC: 0.77348 R²: 0.05411 sex, age, array, PCs 1-10 —
PPM037802 PGS019620
(TPMI_696.41_PRS-CS)
 PSS013510|
East Asian Ancestry|
17,325 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis vulgaris — AUROC: 0.7987 R²: 0.06619 sex, age, array, PCs 1-10 —
PPM037803 PGS019621
(TPMI_696.41_PRSmix+)
 PSS013511|
East Asian Ancestry|
17,325 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis vulgaris — AUROC: 0.82206 R²: 0.07724 sex, age, array, PCs 1-10 —
PPM037804 PGS019622
(TPMI_696.41_SBayesR)
 PSS013512|
East Asian Ancestry|
17,325 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Psoriasis vulgaris — AUROC: 0.80295 R²: 0.06762 sex, age, array, PCs 1-10 —
PPM037816 PGS019634
(TPMI_706.1_Lassosum2)
 PSS013532|
East Asian Ancestry|
19,142 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Acne — AUROC: 0.76402 R²: 0.07598 sex, age, array, PCs 1-10 —
PPM037817 PGS019635
(TPMI_706.1_LDpred2)
 PSS013531|
East Asian Ancestry|
19,142 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Acne — AUROC: 0.76413 R²: 0.07611 sex, age, array, PCs 1-10 —
PPM037818 PGS019636
(TPMI_706.1_MegaPRS)
 PSS013533|
East Asian Ancestry|
19,142 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Acne — AUROC: 0.76454 R²: 0.07604 sex, age, array, PCs 1-10 —
PPM037819 PGS019637
(TPMI_706.1_PRS-CS)
 PSS013534|
East Asian Ancestry|
19,142 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Acne — AUROC: 0.76392 R²: 0.07603 sex, age, array, PCs 1-10 —
PPM037820 PGS019638
(TPMI_706.1_SBayesR)
 PSS013535|
East Asian Ancestry|
19,142 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Acne — AUROC: 0.7639 R²: 0.07599 sex, age, array, PCs 1-10 —
PPM037960 PGS019778
(TPMI_939_Lassosum2)
 PSS013681|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.64773 R²: 0.11815 sex, age, array, PCs 1-10 —
PPM037961 PGS019779
(TPMI_939_LDpred2)
 PSS013680|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.6504 R²: 0.1221 sex, age, array, PCs 1-10 —
PPM037962 PGS019780
(TPMI_939_MegaPRS)
 PSS013682|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.64859 R²: 0.11974 sex, age, array, PCs 1-10 —
PPM037963 PGS019781
(TPMI_939_PRS-CS)
 PSS013683|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.64941 R²: 0.1206 sex, age, array, PCs 1-10 —
PPM037964 PGS019782
(TPMI_939_SBayesR)
 PSS013684|
East Asian Ancestry|
18,563 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Atopic contact dermatitis due to other or unspecified — AUROC: 0.64793 R²: 0.11859 sex, age, array, PCs 1-10 —
PPM037965 PGS019783
(TPMI_947_Lassosum2)
 PSS013686|
East Asian Ancestry|
17,261 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urticaria — AUROC: 0.6988 R²: 0.15105 sex, age, array, PCs 1-10 —
PPM037966 PGS019784
(TPMI_947_LDpred2)
 PSS013685|
East Asian Ancestry|
17,261 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urticaria — AUROC: 0.70011 R²: 0.15277 sex, age, array, PCs 1-10 —
PPM037967 PGS019785
(TPMI_947_MegaPRS)
 PSS013687|
East Asian Ancestry|
17,261 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urticaria — AUROC: 0.70174 R²: 0.15568 sex, age, array, PCs 1-10 —
PPM037968 PGS019786
(TPMI_947_PRS-CS)
 PSS013688|
East Asian Ancestry|
17,261 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urticaria — AUROC: 0.69915 R²: 0.15139 sex, age, array, PCs 1-10 —
PPM037969 PGS019787
(TPMI_947_SBayesR)
 PSS013689|
East Asian Ancestry|
17,261 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Urticaria — AUROC: 0.6994 R²: 0.15197 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS004156 — —
[
  • 850 cases
  • , 6,981 controls
]
 — South Asian — UKB —
PSS004157 — —
[
  • 6,461 cases
  • , 60,964 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004158 — —
[
  • 32 cases
  • , 6,465 controls
]
 — African unspecified — UKB —
PSS004159 — —
[
  • 22 cases
  • , 1,682 controls
]
 — East Asian — UKB —
PSS004160 — —
[
  • 723 cases
  • , 24,182 controls
]
 — European non-white British ancestry UKB —
PSS004161 — —
[
  • 186 cases
  • , 7,645 controls
]
 — South Asian — UKB —
PSS004162 — —
[
  • 1,956 cases
  • , 65,469 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS011691 — —
[
  • 88 cases
  • , 3,124 controls
]
 — European — BSTOP —
PSS004173 — —
[
  • 17 cases
  • , 6,480 controls
]
 — African unspecified — UKB —
PSS004174 — —
[
  • 6 cases
  • , 1,698 controls
]
 — East Asian — UKB —
PSS004175 — —
[
  • 45 cases
  • , 24,860 controls
]
 — European non-white British ancestry UKB —
PSS004176 — —
[
  • 71 cases
  • , 7,760 controls
]
 — South Asian — UKB —
PSS004177 — —
[
  • 131 cases
  • , 67,294 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS008675 — — 6,554 individuals — European Italy (South Europe) UKB —
PSS012093 — — 4,151 individuals — European — BSTOP 4,151 in BSTOP is compared against 9426 UKB
PSS012093 — — 9,426 individuals — European — UKB 4,151 in BSTOP is compared against 9426 UKB
PSS012094 — —
[
  • 1,639 cases
  • , 12,528 controls
]
 — European
(Estonian)		 — EB —
PSS012095 — —
[
  • 5,365 cases
  • , 7,343 controls
]
 — European
(Finnish)		 — FinnGen —
PSS012096 — —
[
  • 1,491 cases
  • , 7,112 controls
]
 — European
(Norwegian)		 — HUNT —
PSS012097 — — 1,461 individuals — European — Novartis 1,461 in Novartis is compared against 9426 UKB
PSS012097 — — 9,426 individuals — European — UKB 1,461 in Novartis is compared against 9426 UKB
PSS012098 — —
[
  • 1,243 cases
  • , 8,183 controls
]
 — European
(British)		 — UKB —
PSS013507 696.1,L40.0, L40.2, L40.3, L40.4, L40.8, L40.9 —
[
  • 275 cases
  • , 17,050 controls
]
,
48.39 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013508 696.1,L40.0, L40.2, L40.3, L40.4, L40.8, L40.9 —
[
  • 275 cases
  • , 17,050 controls
]
,
48.39 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013509 696.1,L40.0, L40.2, L40.3, L40.4, L40.8, L40.9 —
[
  • 275 cases
  • , 17,050 controls
]
,
48.39 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013510 696.1,L40.0, L40.2, L40.3, L40.4, L40.8, L40.9 —
[
  • 275 cases
  • , 17,050 controls
]
,
48.39 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013511 696.1,L40.0, L40.2, L40.3, L40.4, L40.8, L40.9 —
[
  • 275 cases
  • , 17,050 controls
]
,
48.39 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013512 696.1,L40.0, L40.2, L40.3, L40.4, L40.8, L40.9 —
[
  • 275 cases
  • , 17,050 controls
]
,
48.39 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013519 696.0, 696.1, 696.8,L40 —
[
  • 320 cases
  • , 17,050 controls
]
,
48.38 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013520 696.0, 696.1, 696.8,L40 —
[
  • 320 cases
  • , 17,050 controls
]
,
48.38 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013521 696.0, 696.1, 696.8,L40 —
[
  • 320 cases
  • , 17,050 controls
]
,
48.38 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013522 696.0, 696.1, 696.8,L40 —
[
  • 320 cases
  • , 17,050 controls
]
,
48.38 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013523 696.0, 696.1, 696.8,L40 —
[
  • 320 cases
  • , 17,050 controls
]
,
48.38 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013524 696.0, 696.1, 696.8,L40 —
[
  • 320 cases
  • , 17,050 controls
]
,
48.38 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013525 696,L30.5, L40, L41, L42, L44.0, L94.5 —
[
  • 330 cases
  • , 17,050 controls
]
,
48.37 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013526 696,L30.5, L40, L41, L42, L44.0, L94.5 —
[
  • 330 cases
  • , 17,050 controls
]
,
48.37 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013527 696,L30.5, L40, L41, L42, L44.0, L94.5 —
[
  • 330 cases
  • , 17,050 controls
]
,
48.37 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013528 696,L30.5, L40, L41, L42, L44.0, L94.5 —
[
  • 330 cases
  • , 17,050 controls
]
,
48.37 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013529 696,L30.5, L40, L41, L42, L44.0, L94.5 —
[
  • 330 cases
  • , 17,050 controls
]
,
48.37 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013530 696,L30.5, L40, L41, L42, L44.0, L94.5 —
[
  • 330 cases
  • , 17,050 controls
]
,
48.37 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013531 706.0, 706.1,L70, L73.0 —
[
  • 233 cases
  • , 18,909 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013532 706.0, 706.1,L70, L73.0 —
[
  • 233 cases
  • , 18,909 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013533 706.0, 706.1,L70, L73.0 —
[
  • 233 cases
  • , 18,909 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS008229 — — 6,161 individuals — South Asian India (South Asia) UKB —
PSS013534 706.0, 706.1,L70, L73.0 —
[
  • 233 cases
  • , 18,909 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013535 706.0, 706.1,L70, L73.0 —
[
  • 233 cases
  • , 18,909 controls
]
,
45.93 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS007794 — — 2,398 individuals — African American or Afro-Caribbean Carribean UKB —
PSS009347 — — 19,615 individuals — European UK (+ Ireland) UKB —
PSS009651 — Median = 10.88 years 345,672 individuals,
48.0 % Male samples
 Mean = 56.53 years
Sd = 8.06 years		 European — UKB —
PSS009939 — — 39,444 individuals — European
(Finnish)		 — FinnGen —
PSS004384 — —
[
  • 157 cases
  • , 6,340 controls
]
 — African unspecified — UKB —
PSS004385 — —
[
  • 66 cases
  • , 1,638 controls
]
 — East Asian — UKB —
PSS004386 — —
[
  • 873 cases
  • , 24,032 controls
]
 — European non-white British ancestry UKB —
PSS004387 — —
[
  • 243 cases
  • , 7,588 controls
]
 — South Asian — UKB —
PSS004388 — —
[
  • 2,514 cases
  • , 64,911 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS013680 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013681 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013682 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013683 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013684 373.32, 691, 692, 693, E866.7,H01.11, L20, L23, L24, L25, L27, L30.0, L30.2, L30.8, L30.9, M04.8 —
[
  • 1,973 cases
  • , 16,590 controls
]
,
46.65 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013685 708,D47.01, D89.4, L50 —
[
  • 671 cases
  • , 16,590 controls
]
,
46.54 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013686 708,D47.01, D89.4, L50 —
[
  • 671 cases
  • , 16,590 controls
]
,
46.54 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013687 708,D47.01, D89.4, L50 —
[
  • 671 cases
  • , 16,590 controls
]
,
46.54 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013688 708,D47.01, D89.4, L50 —
[
  • 671 cases
  • , 16,590 controls
]
,
46.54 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013689 708,D47.01, D89.4, L50 —
[
  • 671 cases
  • , 16,590 controls
]
,
46.54 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS008898 — — 3,834 individuals — African unspecified Nigeria (West Africa) UKB —
PSS000907 Cases are individuals with vitiligo. Diagnoses of vitiligo in multiplex-affected subjects and reportedly unaffected family members were verified by manual review of all available phenotype information for each subject. —
[
  • 1,827 cases
  • , 2,181 controls
]
 — European — NR —
PSS011347 — —
[
  • 1,277 cases
  • , 66,151 controls
]
,
46.0 % Male samples
 — European
(White British)		 — UKB —
PSS011348 — — 345 individuals,
52.0 % Male samples
 Mean = 49.0 years
Sd = 16.0 years		 European — UCSF —
PSS011349 — — 654 individuals,
48.0 % Male samples
 Mean = 41.0 years
Sd = 14.0 years		 European — NR —
PSS004471 — —
[
  • 19 cases
  • , 6,478 controls
]
 — African unspecified — UKB —
PSS004472 — —
[
  • 10 cases
  • , 1,694 controls
]
 — East Asian — UKB —
PSS004473 — —
[
  • 416 cases
  • , 24,489 controls
]
 — European non-white British ancestry UKB —
PSS004474 — —
[
  • 108 cases
  • , 7,723 controls
]
 — South Asian — UKB —
PSS004475 — —
[
  • 1,146 cases
  • , 66,279 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS008449 — — 1,183 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS010968 — —
[
  • 3,750 cases
  • , 952 controls
]
 — European — NR GCAT
PSS010969 — —
[
  • 243 cases
  • , 4,702 controls
]
 — European — NR GCAT
PSS010974 — —
[
  • 34 cases
  • , 4,945 controls
]
 — European — NR GCAT
PSS010977 — — 4,987 individuals — European — NR GCAT
PSS011376 — Median = 12.0 years 337,910 individuals,
45.6 % Male samples
 Mean = 57.1 years
Sd = 8.0 years		 European — UKB —
PSS008010 — — 1,784 individuals — East Asian China (East Asia) UKB —
PSS007661 For the CHILD Cohort Study, atopic dermatitis (AD) was from physician diagnosis at the one year follow-up. AD severity was defined as mild if there is a single site or no more than 2 sites, minor symptoms (little itching/rubbing), minor crusting and papules, not excoriated or oozing, not needing frequent medical attention; was defined as moderate if symptoms are neither mild nor severe or; was defined as severe if there are multiple sites, with extensive crusting or papules or excoriations or oozing or lichenification, sleep loss, needing frequent medical attention, and is a major concern to parents. In the SLSJ Cohort, atopic dermatitis was self-reported and considered as positive if past or present occurrence was reported. For children, cross validation was done using questionnaires filled by their parents. Moreover, validation in medical records of these self-reported phenotypes were done for a subset of the SLSJ Cohort (n = 217), giving 89% concordance. —
[
  • 61 cases
  • , 615 controls
]
,
42.0 % Male samples
 Mean = 9.0 years
Range = [0.0, 87.0] years		 European, South East Asian, East Asian, South Asian, African American or Afro-Caribbean, Native American, Greater Middle Eastern (Middle Eastern, North African or Persian), Hispanic or Latin American, Not reported — CHILD, SLSJ Also used to evaluate the PRS_atopicDermatitis for other diseases of the atopic march: food allergy, allergic asthma and rhinitis. Only unrelated individuals were selected for analyses.
PSS012347 110.1,B35.1 —
[
  • 519 cases
  • , 18,156 controls
]
,
45.96 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012348 110.1,B35.1 —
[
  • 519 cases
  • , 18,156 controls
]
,
45.96 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012349 110.1,B35.1 —
[
  • 519 cases
  • , 18,156 controls
]
,
45.96 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012350 110.1,B35.1 —
[
  • 519 cases
  • , 18,156 controls
]
,
45.96 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012351 110.1,B35.1 —
[
  • 519 cases
  • , 18,156 controls
]
,
45.96 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012352 110.3, 110.5,B35.4, B35.5, B35.6 —
[
  • 224 cases
  • , 18,156 controls
]
,
45.83 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012353 110.3, 110.5,B35.4, B35.5, B35.6 —
[
  • 224 cases
  • , 18,156 controls
]
,
45.83 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012354 110.3, 110.5,B35.4, B35.5, B35.6 —
[
  • 224 cases
  • , 18,156 controls
]
,
45.83 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS000970 — Median = 400.0 days 1,584 individuals — European — GNEHGI2020Q2 —
PSS012355 110.3, 110.5,B35.4, B35.5, B35.6 —
[
  • 224 cases
  • , 18,156 controls
]
,
45.83 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012356 110.3, 110.5,B35.4, B35.5, B35.6 —
[
  • 224 cases
  • , 18,156 controls
]
,
45.83 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS009819 — — 6,503 individuals — African unspecified — UKB —
PSS009820 — — 922 individuals — East Asian — UKB —
PSS009821 — — 43,505 individuals — European Non-British European UKB —
PSS009822 — — 8,098 individuals — South Asian — UKB —
PSS010186 Plaque psoriasis patients with at least one exposure to biologic therapy. Cases developed one or more paradoxical eczema adverse events during treatment with one of the following biologics: TNF-alpha inhibitors (adalimumab; etanercept; certolizumab; infliximab), IL-17 inhibitors (brodalumab; secukinumab; ixekizumab), IL-12/23 inhibitors (ustekinumab) and IL-23p19 inhibitors (guselkumab; risankizumab; tildrakizumab). Controls has no recorded eczema events during biologic therapy. Participants may have been exposed to more than one biologic. —
[
  • 88 cases
  • , 3,124 controls
]
 — European — BSTOP —
PSS009121 — — 4,059 individuals — European Poland (NE Europe) UKB —
PSS004153 — —
[
  • 343 cases
  • , 6,154 controls
]
 — African unspecified — UKB —
PSS004154 — —
[
  • 143 cases
  • , 1,561 controls
]
 — East Asian — UKB —
PSS004155 — —
[
  • 2,053 cases
  • , 22,852 controls
]
 — European non-white British ancestry UKB —