Trait: otorhinolaryngologic disease

Trait Information
Identifier MONDO_0024623
Description Pathological processes of the ear, the nose, and the throat, also known as the ENT diseases. [MESH: D010038]
Trait category
Other disease
Synonyms 23 synonyms
  • ENT disease
  • ENT diseases
  • disease, ENT
  • disease, otolaryngologic
  • disease, otolaryngological
  • disease, otorhinolaryngologic
  • disease, otorhinolaryngological
  • diseases, ENT
  • diseases, otolaryngologic
  • diseases, otolaryngological
  • diseases, otorhinolaryngologic
  • diseases, otorhinolaryngological
  • ear, nose and throat disorder
  • ear, nose or throat disorder
  • ear/nose/throat disease
  • otolaryngologic disease
  • otolaryngologic diseases
  • otolaryngologic disorder
  • otolaryngological disease
  • otolaryngological diseases
  • otorhinolaryngologic disease
  • otorhinolaryngological disease
  • otorhinolaryngological diseases
Child trait(s) 14 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows PGS for child terms of "otorhinolaryngologic disease" in the EFO hierarchy.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000081
(CC_Oral)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Oral cavity and pharyngeal cancers oral cavity cancer,
pharynx cancer		 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000081/ScoringFiles/PGS000081.txt.gz
PGS000792
(CC_Oral_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Oral cavity and pharyngeal cancers oral cavity cancer,
pharynx cancer		 14
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000792/ScoringFiles/PGS000792.txt.gz
PGS001109
(GBE_HC1021)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Vasomotor and allergic rhinitis (time-to-event) vasomotor rhinitis,
allergic rhinitis		 1,910
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001109/ScoringFiles/PGS001109.txt.gz
PGS001255
(GBE_HC914)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Otosclerosis (time-to-event) otosclerosis 213
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001255/ScoringFiles/PGS001255.txt.gz
PGS001259
(GBE_HC49)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Hayfever/allergic rhinitis seasonal allergic rhinitis 349
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001259/ScoringFiles/PGS001259.txt.gz
PGS002046
(portability-ldpred2_383)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Otosclerosis otosclerosis 570,308
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002046/ScoringFiles/PGS002046.txt.gz
PGS002291
(PRS12_NPC)
 PGP000320 |
He YQ et al. Nat Commun (2022)
 Nasopharyngeal carcinoma nasopharyngeal neoplasm 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002291/ScoringFiles/PGS002291.txt.gz
PGS004465
(disease.J33.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 J33 (Nasal polyp) nasal cavity polyp 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004465/ScoringFiles/PGS004465.txt.gz
PGS004535
(meta.J33.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 J33 (Nasal polyp) nasal cavity polyp 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004535/ScoringFiles/PGS004535.txt.gz
PGS012588
(PRS_HNC_OPC)
 PGP000822 |
Lee YC et al. BMC Med (2024)
 Oropharynx cancer oropharynx cancer 972,182
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012588/ScoringFiles/PGS012588.txt.gz
PGS018470
(TPMI_149.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cancer of nasopharynx malignant tumor of nasopharynx 211
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018470/ScoringFiles/PGS018470.txt.gz
PGS018471
(TPMI_149.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cancer of nasopharynx malignant tumor of nasopharynx 45,670
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018471/ScoringFiles/PGS018471.txt.gz
PGS018472
(TPMI_149.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cancer of nasopharynx malignant tumor of nasopharynx 10,449
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018472/ScoringFiles/PGS018472.txt.gz
PGS018473
(TPMI_149.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cancer of nasopharynx malignant tumor of nasopharynx 983,776
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018473/ScoringFiles/PGS018473.txt.gz
PGS018474
(TPMI_149.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Cancer of nasopharynx malignant tumor of nasopharynx 1,005,312
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018474/ScoringFiles/PGS018474.txt.gz
PGS019076
(TPMI_381.11_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Suppurative and unspecified otitis media otitis media 46,921
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019076/ScoringFiles/PGS019076.txt.gz
PGS019077
(TPMI_381.11_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Suppurative and unspecified otitis media otitis media 939,893
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019077/ScoringFiles/PGS019077.txt.gz
PGS019078
(TPMI_381.11_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Suppurative and unspecified otitis media otitis media 486,781
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019078/ScoringFiles/PGS019078.txt.gz
PGS019079
(TPMI_381.11_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Suppurative and unspecified otitis media otitis media 983,826
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019079/ScoringFiles/PGS019079.txt.gz
PGS019080
(TPMI_381.11_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Suppurative and unspecified otitis media otitis media 999,521
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019080/ScoringFiles/PGS019080.txt.gz
PGS019081
(TPMI_386_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Vertiginous syndromes and other disorders of vestibular system vestibular disorder 125,242
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019081/ScoringFiles/PGS019081.txt.gz
PGS019082
(TPMI_386_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Vertiginous syndromes and other disorders of vestibular system vestibular disorder 939,898
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019082/ScoringFiles/PGS019082.txt.gz
PGS019083
(TPMI_386_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Vertiginous syndromes and other disorders of vestibular system vestibular disorder 22,265
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019083/ScoringFiles/PGS019083.txt.gz
PGS019084
(TPMI_386_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Vertiginous syndromes and other disorders of vestibular system vestibular disorder 983,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019084/ScoringFiles/PGS019084.txt.gz
PGS019085
(TPMI_386_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Vertiginous syndromes and other disorders of vestibular system vestibular disorder 914,097
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019085/ScoringFiles/PGS019085.txt.gz
PGS019086
(TPMI_386.1_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Menieres disease Meniere disease 802,789
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019086/ScoringFiles/PGS019086.txt.gz
PGS019087
(TPMI_386.1_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Menieres disease Meniere disease 939,888
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019087/ScoringFiles/PGS019087.txt.gz
PGS019088
(TPMI_386.1_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Menieres disease Meniere disease 23,220
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019088/ScoringFiles/PGS019088.txt.gz
PGS019089
(TPMI_386.1_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Menieres disease Meniere disease 983,823
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019089/ScoringFiles/PGS019089.txt.gz
PGS019090
(TPMI_386.1_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Menieres disease Meniere disease 987,552
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019090/ScoringFiles/PGS019090.txt.gz
PGS019096
(TPMI_386.3_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Labyrinthitis labyrinthitis 245
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019096/ScoringFiles/PGS019096.txt.gz
PGS019097
(TPMI_386.3_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Labyrinthitis labyrinthitis 939,831
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019097/ScoringFiles/PGS019097.txt.gz
PGS019098
(TPMI_386.3_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Labyrinthitis labyrinthitis 14,820
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019098/ScoringFiles/PGS019098.txt.gz
PGS019099
(TPMI_386.3_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Labyrinthitis labyrinthitis 983,780
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019099/ScoringFiles/PGS019099.txt.gz
PGS019100
(TPMI_386.3_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Labyrinthitis labyrinthitis 957,643
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019100/ScoringFiles/PGS019100.txt.gz
PGS019270
(TPMI_475_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic sinusitis chronic rhinosinusitis 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019270/ScoringFiles/PGS019270.txt.gz
PGS019271
(TPMI_475_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic sinusitis chronic rhinosinusitis 939,862
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019271/ScoringFiles/PGS019271.txt.gz
PGS019272
(TPMI_475_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic sinusitis chronic rhinosinusitis 15,628
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019272/ScoringFiles/PGS019272.txt.gz
PGS019273
(TPMI_475_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic sinusitis chronic rhinosinusitis 983,804
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019273/ScoringFiles/PGS019273.txt.gz
PGS019274
(TPMI_475_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic sinusitis chronic rhinosinusitis 968,351
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019274/ScoringFiles/PGS019274.txt.gz
PGS019275
(TPMI_476_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Allergic rhinitis allergic rhinitis 243,320
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019275/ScoringFiles/PGS019275.txt.gz
PGS019276
(TPMI_476_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Allergic rhinitis allergic rhinitis 939,881
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019276/ScoringFiles/PGS019276.txt.gz
PGS019277
(TPMI_476_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Allergic rhinitis allergic rhinitis 17,340
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019277/ScoringFiles/PGS019277.txt.gz
PGS019278
(TPMI_476_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Allergic rhinitis allergic rhinitis 983,820
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019278/ScoringFiles/PGS019278.txt.gz
PGS019279
(TPMI_476_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Allergic rhinitis allergic rhinitis 950,545
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019279/ScoringFiles/PGS019279.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000201 PGS000081
(CC_Oral)
 PSS000120|
European Ancestry|
411,577 individuals
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Reported Trait: Oral cavity and pharyngeal cancers OR: 1.08 [1.02, 1.14] — — Genotyping reagent kit (GERA cohort only), genotyping array (UK Biobank only), age, sex, 10 PCs. Results from meta-analysis of GERA and UKB
PPM002047 PGS000081
(CC_Oral)
 PSS001020|
European Ancestry|
391,479 individuals
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
|Ext.		 Reported Trait: Incident oral cavity and pharyngeal cancer HR: 1.11 [1.01, 1.21] AUROC: 0.702
C-index: 0.686 (0.015)		 — Age at assessment, sex, genotyping array, PCs(1-15), weekly alcohol intake, cigarettes per day, years of smoking, smoing status (never vs. former vs. current) C-index calculated as a weighted average between 1 and 5 years and AUC at 5 years.
PPM017173 PGS000081
(CC_Oral)
 PSS010150|
European Ancestry|
415 individuals
 PGP000443 |
Byrne S et al. Int J Epidemiol (2023)
|Ext.		 Reported Trait: Oral cavity and pharyngeal cancers HR: 1.03 [0.94, 1.14] — — age at baseline, sex (where relevant), assessment centre, 40 principal components of ancestries (PCs), Townsend Index, education, birth location, income, lifestyle index, additional cancer-specific covariates —
PPM002063 PGS000792
(CC_Oral_IV)
 PSS001020|
European Ancestry|
391,479 individuals
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Reported Trait: Incident oral cavity and pharyngeal cancer HR: 1.12 [1.02, 1.23] AUROC: 0.702
C-index: 0.687 (0.015)		 R²: 0.356 Age at assessment, sex, genotyping array, PCs(1-15), weekly alcohol intake, cigarettes per day, years of smoking, smoing status (never vs. former vs. current) C-index calculated as a weighted average between 1 and 5 years and AUC at 5 years.
PPM008284 PGS001109
(GBE_HC1021)
 PSS004069|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vasomotor and allergic rhinitis — AUROC: 0.5683 [0.54473, 0.59188] R²: 0.01206
Incremental AUROC (full-covars): 0.00409
PGS R2 (no covariates): 0.00275
PGS AUROC (no covariates): 0.53243 [0.50926, 0.55561]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008285 PGS001109
(GBE_HC1021)
 PSS004070|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vasomotor and allergic rhinitis — AUROC: 0.54528 [0.51116, 0.5794] R²: 0.01457
Incremental AUROC (full-covars): 0.00387
PGS R2 (no covariates): 0.00105
PGS AUROC (no covariates): 0.51375 [0.47834, 0.54917]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008286 PGS001109
(GBE_HC1021)
 PSS004071|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vasomotor and allergic rhinitis — AUROC: 0.6003 [0.58786, 0.61273] R²: 0.0217
Incremental AUROC (full-covars): 0.02658
PGS R2 (no covariates): 0.00981
PGS AUROC (no covariates): 0.56712 [0.55454, 0.57969]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008287 PGS001109
(GBE_HC1021)
 PSS004072|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vasomotor and allergic rhinitis — AUROC: 0.55379 [0.53392, 0.57366] R²: 0.00762
Incremental AUROC (full-covars): 0.0079
PGS R2 (no covariates): 0.00254
PGS AUROC (no covariates): 0.53239 [0.51256, 0.55222]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008288 PGS001109
(GBE_HC1021)
 PSS004073|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE vasomotor and allergic rhinitis — AUROC: 0.59854 [0.59138, 0.6057] R²: 0.02303
Incremental AUROC (full-covars): 0.02878
PGS R2 (no covariates): 0.0118
PGS AUROC (no covariates): 0.56998 [0.56268, 0.57727]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008781 PGS001255
(GBE_HC914)
 PSS004702|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE otosclerosis — AUROC: 0.91156 [0.77281, 1.0] R²: 0.29139
Incremental AUROC (full-covars): 0.03981
PGS R2 (no covariates): 0.06779
PGS AUROC (no covariates): 0.7376 [0.46621, 1.0]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008782 PGS001255
(GBE_HC914)
 PSS004703|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE otosclerosis — AUROC: 0.66807 [0.58985, 0.74629] R²: 0.03365
Incremental AUROC (full-covars): 0.05467
PGS R2 (no covariates): 0.01522
PGS AUROC (no covariates): 0.62631 [0.54794, 0.70468]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008783 PGS001255
(GBE_HC914)
 PSS004704|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE otosclerosis — AUROC: 0.71231 [0.61511, 0.80951] R²: 0.04349
Incremental AUROC (full-covars): 0.03275
PGS R2 (no covariates): 0.00824
PGS AUROC (no covariates): 0.59763 [0.48884, 0.70642]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008784 PGS001255
(GBE_HC914)
 PSS004705|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE otosclerosis — AUROC: 0.6532 [0.60975, 0.69665] R²: 0.02085
Incremental AUROC (full-covars): 0.05946
PGS R2 (no covariates): 0.01341
PGS AUROC (no covariates): 0.6319 [0.58724, 0.67656]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008800 PGS001259
(GBE_HC49)
 PSS004511|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hayfever/allergic rhinitis — AUROC: 0.58821 [0.55886, 0.61757] R²: 0.01784
Incremental AUROC (full-covars): -0.00253
PGS R2 (no covariates): 0.00082
PGS AUROC (no covariates): 0.51547 [0.48626, 0.54467]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008801 PGS001259
(GBE_HC49)
 PSS004512|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hayfever/allergic rhinitis — AUROC: 0.56313 [0.52505, 0.60122] R²: 0.02281
Incremental AUROC (full-covars): 0.00075
PGS R2 (no covariates): 0.0011
PGS AUROC (no covariates): 0.52627 [0.48539, 0.56716]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008802 PGS001259
(GBE_HC49)
 PSS004513|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hayfever/allergic rhinitis — AUROC: 0.60641 [0.59175, 0.62107] R²: 0.02043
Incremental AUROC (full-covars): 0.01519
PGS R2 (no covariates): 0.00564
PGS AUROC (no covariates): 0.55414 [0.53891, 0.56936]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008803 PGS001259
(GBE_HC49)
 PSS004514|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hayfever/allergic rhinitis — AUROC: 0.60093 [0.57427, 0.6276] R²: 0.02041
Incremental AUROC (full-covars): 0.00631
PGS R2 (no covariates): 0.00266
PGS AUROC (no covariates): 0.54086 [0.51259, 0.56913]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008804 PGS001259
(GBE_HC49)
 PSS004515|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Hayfever/allergic rhinitis — AUROC: 0.60078 [0.59218, 0.60937] R²: 0.02042
Incremental AUROC (full-covars): 0.01922
PGS R2 (no covariates): 0.00737
PGS AUROC (no covariates): 0.5597 [0.55096, 0.56843]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM011232 PGS002046
(portability-ldpred2_383)
 PSS009309|
European Ancestry|
19,770 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Otosclerosis — — Partial Correlation (partial-r): 0.0182 [0.0043, 0.0321] sex, age, birth date, deprivation index, 16 PCs —
PPM011233 PGS002046
(portability-ldpred2_383)
 PSS009083|
European Ancestry|
4,097 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Otosclerosis — — Partial Correlation (partial-r): 0.0328 [0.0021, 0.0634] sex, age, birth date, deprivation index, 16 PCs —
PPM011234 PGS002046
(portability-ldpred2_383)
 PSS008637|
European Ancestry|
6,611 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Otosclerosis — — Partial Correlation (partial-r): -0.0025 [-0.0266, 0.0217] sex, age, birth date, deprivation index, 16 PCs —
PPM011235 PGS002046
(portability-ldpred2_383)
 PSS008411|
Greater Middle Eastern Ancestry|
1,182 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Otosclerosis — — Partial Correlation (partial-r): 0.0315 [-0.026, 0.0889] sex, age, birth date, deprivation index, 16 PCs —
PPM011236 PGS002046
(portability-ldpred2_383)
 PSS008191|
South Asian Ancestry|
6,238 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Otosclerosis — — Partial Correlation (partial-r): 0.0251 sex, age, birth date, deprivation index, 16 PCs —
PPM011237 PGS002046
(portability-ldpred2_383)
 PSS007756|
African Ancestry|
2,469 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Otosclerosis — — Partial Correlation (partial-r): 0.0104 [-0.0293, 0.0499] sex, age, birth date, deprivation index, 16 PCs —
PPM013010 PGS002291
(PRS12_NPC)
 PSS009646|
East Asian Ancestry|
2,893 individuals
 PGP000320 |
He YQ et al. Nat Commun (2022)
 Reported Trait: Nasopharyngeal carcinoma — AUROC: 0.64 — — —
PPM013011 PGS002291
(PRS12_NPC)
 PSS009646|
East Asian Ancestry|
2,893 individuals
 PGP000320 |
He YQ et al. Nat Commun (2022)
 Reported Trait: Nasopharyngeal carcinoma — AUROC: 0.69 — Family history of NPC —
PPM022453 PGS002291
(PRS12_NPC)
 PSS011948|
East Asian Ancestry|
4,804 individuals
 PGP000714 |
Diao H et al. J Med Virol (2023)
|Ext.		 Reported Trait: Nasopharyngeal carcinoma — — Odds ratio (OR, high vs low tertile): 2.57 [2.28, 2.9] — —
PPM022454 PGS002291
(PRS12_NPC)
 PSS011948|
East Asian Ancestry|
4,804 individuals
 PGP000714 |
Diao H et al. J Med Virol (2023)
|Ext.		 Reported Trait: Nasopharyngeal carcinoma x VCA-IgA interaction — — Odds ratio (OR, positive VCA-IgA and high PRS vs. negative VCA-IgA and low PRS): 257.96 [178.2, 386.23]
Synergy index (SI): 3.1 [2.17, 4.44]		 — —
PPM020580 PGS004465
(disease.J33.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: J33 (Nasal polyp) OR: 1.3496 — — — —
PPM020650 PGS004535
(meta.J33.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: J33 (Nasal polyp) OR: 1.60067 — — — —
PPM030761 PGS012588
(PRS_HNC_OPC)
 PSS012283|
Multi-ancestry (including European)|
37,901 individuals
 PGP000822 |
Lee YC et al. BMC Med (2024)
 Reported Trait: Oropharynx cancer OR: 1.24 [1.08, 1.42] — — age, sex, ethnicity, and PC 1 to 10 —
PPM030757 PGS012588
(PRS_HNC_OPC)
 PSS012284|
European Ancestry|
307,295 individuals
 PGP000822 |
Lee YC et al. BMC Med (2024)
 Reported Trait: Oropharynx cancer OR: 1.09 [1.02, 1.17] — — age, sex, genotype array, and PC 1 to 10 —
PPM036652 PGS018470
(TPMI_149.2_Lassosum2)
 PSS012368|
East Asian Ancestry|
19,070 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cancer of nasopharynx — AUROC: 0.7073 R²: 0.01637 sex, age, array, PCs 1-10 —
PPM036653 PGS018471
(TPMI_149.2_LDpred2)
 PSS012367|
East Asian Ancestry|
19,070 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cancer of nasopharynx — AUROC: 0.71186 R²: 0.01717 sex, age, array, PCs 1-10 —
PPM036654 PGS018472
(TPMI_149.2_MegaPRS)
 PSS012369|
East Asian Ancestry|
19,070 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cancer of nasopharynx — AUROC: 0.69527 R²: 0.01463 sex, age, array, PCs 1-10 —
PPM036655 PGS018473
(TPMI_149.2_PRS-CS)
 PSS012370|
East Asian Ancestry|
19,070 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cancer of nasopharynx — AUROC: 0.70955 R²: 0.0161 sex, age, array, PCs 1-10 —
PPM036656 PGS018474
(TPMI_149.2_SBayesR)
 PSS012371|
East Asian Ancestry|
19,070 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Cancer of nasopharynx — AUROC: 0.69866 R²: 0.01489 sex, age, array, PCs 1-10 —
PPM037258 PGS019076
(TPMI_381.11_Lassosum2)
 PSS012979|
East Asian Ancestry|
19,521 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Suppurative and unspecified otitis media — AUROC: 0.63418 R²: 0.01229 sex, age, array, PCs 1-10 —
PPM037259 PGS019077
(TPMI_381.11_LDpred2)
 PSS012978|
East Asian Ancestry|
19,521 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Suppurative and unspecified otitis media — AUROC: 0.63992 R²: 0.01294 sex, age, array, PCs 1-10 —
PPM037260 PGS019078
(TPMI_381.11_MegaPRS)
 PSS012980|
East Asian Ancestry|
19,521 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Suppurative and unspecified otitis media — AUROC: 0.63614 R²: 0.01221 sex, age, array, PCs 1-10 —
PPM037261 PGS019079
(TPMI_381.11_PRS-CS)
 PSS012981|
East Asian Ancestry|
19,521 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Suppurative and unspecified otitis media — AUROC: 0.63258 R²: 0.01178 sex, age, array, PCs 1-10 —
PPM037262 PGS019080
(TPMI_381.11_SBayesR)
 PSS012982|
East Asian Ancestry|
19,521 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Suppurative and unspecified otitis media — AUROC: 0.63187 R²: 0.0115 sex, age, array, PCs 1-10 —
PPM037263 PGS019081
(TPMI_386_Lassosum2)
 PSS013009|
East Asian Ancestry|
19,232 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Vertiginous syndromes and other disorders of vestibular system — AUROC: 0.59319 R²: 0.03898 sex, age, array, PCs 1-10 —
PPM037264 PGS019082
(TPMI_386_LDpred2)
 PSS013008|
East Asian Ancestry|
19,232 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Vertiginous syndromes and other disorders of vestibular system — AUROC: 0.59425 R²: 0.04012 sex, age, array, PCs 1-10 —
PPM037265 PGS019083
(TPMI_386_MegaPRS)
 PSS013010|
East Asian Ancestry|
19,232 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Vertiginous syndromes and other disorders of vestibular system — AUROC: 0.59217 R²: 0.03816 sex, age, array, PCs 1-10 —
PPM037266 PGS019084
(TPMI_386_PRS-CS)
 PSS013011|
East Asian Ancestry|
19,232 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Vertiginous syndromes and other disorders of vestibular system — AUROC: 0.5934 R²: 0.0392 sex, age, array, PCs 1-10 —
PPM037267 PGS019085
(TPMI_386_SBayesR)
 PSS013012|
East Asian Ancestry|
19,232 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Vertiginous syndromes and other disorders of vestibular system — AUROC: 0.59204 R²: 0.03809 sex, age, array, PCs 1-10 —
PPM037268 PGS019086
(TPMI_386.1_Lassosum2)
 PSS012984|
East Asian Ancestry|
17,579 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Menieres disease — AUROC: 0.61707 R²: 0.01248 sex, age, array, PCs 1-10 —
PPM037269 PGS019087
(TPMI_386.1_LDpred2)
 PSS012983|
East Asian Ancestry|
17,579 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Menieres disease — AUROC: 0.61731 R²: 0.01262 sex, age, array, PCs 1-10 —
PPM037270 PGS019088
(TPMI_386.1_MegaPRS)
 PSS012985|
East Asian Ancestry|
17,579 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Menieres disease — AUROC: 0.61749 R²: 0.01255 sex, age, array, PCs 1-10 —
PPM037271 PGS019089
(TPMI_386.1_PRS-CS)
 PSS012986|
East Asian Ancestry|
17,579 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Menieres disease — AUROC: 0.61682 R²: 0.01254 sex, age, array, PCs 1-10 —
PPM037272 PGS019090
(TPMI_386.1_SBayesR)
 PSS012987|
East Asian Ancestry|
17,579 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Menieres disease — AUROC: 0.61747 R²: 0.01243 sex, age, array, PCs 1-10 —
PPM037278 PGS019096
(TPMI_386.3_Lassosum2)
 PSS012999|
East Asian Ancestry|
17,995 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Labyrinthitis — AUROC: 0.57817 R²: 0.00841 sex, age, array, PCs 1-10 —
PPM037279 PGS019097
(TPMI_386.3_LDpred2)
 PSS012998|
East Asian Ancestry|
17,995 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Labyrinthitis — AUROC: 0.58246 R²: 0.00937 sex, age, array, PCs 1-10 —
PPM037280 PGS019098
(TPMI_386.3_MegaPRS)
 PSS013000|
East Asian Ancestry|
17,995 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Labyrinthitis — AUROC: 0.58134 R²: 0.0089 sex, age, array, PCs 1-10 —
PPM037281 PGS019099
(TPMI_386.3_PRS-CS)
 PSS013001|
East Asian Ancestry|
17,995 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Labyrinthitis — AUROC: 0.58388 R²: 0.00948 sex, age, array, PCs 1-10 —
PPM037282 PGS019100
(TPMI_386.3_SBayesR)
 PSS013002|
East Asian Ancestry|
17,995 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Labyrinthitis — AUROC: 0.57912 R²: 0.0088 sex, age, array, PCs 1-10 —
PPM037452 PGS019270
(TPMI_475_Lassosum2)
 PSS013173|
East Asian Ancestry|
16,060 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Chronic sinusitis — AUROC: 0.64256 R²: 0.04727 sex, age, array, PCs 1-10 —
PPM037453 PGS019271
(TPMI_475_LDpred2)
 PSS013172|
East Asian Ancestry|
16,060 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Chronic sinusitis — AUROC: 0.6436 R²: 0.04727 sex, age, array, PCs 1-10 —
PPM037454 PGS019272
(TPMI_475_MegaPRS)
 PSS013174|
East Asian Ancestry|
16,060 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Chronic sinusitis — AUROC: 0.63977 R²: 0.0454 sex, age, array, PCs 1-10 —
PPM037455 PGS019273
(TPMI_475_PRS-CS)
 PSS013175|
East Asian Ancestry|
16,060 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Chronic sinusitis — AUROC: 0.64175 R²: 0.04626 sex, age, array, PCs 1-10 —
PPM037456 PGS019274
(TPMI_475_SBayesR)
 PSS013176|
East Asian Ancestry|
16,060 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Chronic sinusitis — AUROC: 0.64071 R²: 0.0455 sex, age, array, PCs 1-10 —
PPM037457 PGS019275
(TPMI_476_Lassosum2)
 PSS013178|
East Asian Ancestry|
17,583 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Allergic rhinitis — AUROC: 0.66159 R²: 0.1223 sex, age, array, PCs 1-10 —
PPM037458 PGS019276
(TPMI_476_LDpred2)
 PSS013177|
East Asian Ancestry|
17,583 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Allergic rhinitis — AUROC: 0.66228 R²: 0.12353 sex, age, array, PCs 1-10 —
PPM037459 PGS019277
(TPMI_476_MegaPRS)
 PSS013179|
East Asian Ancestry|
17,583 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Allergic rhinitis — AUROC: 0.66233 R²: 0.12293 sex, age, array, PCs 1-10 —
PPM037460 PGS019278
(TPMI_476_PRS-CS)
 PSS013180|
East Asian Ancestry|
17,583 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Allergic rhinitis — AUROC: 0.66181 R²: 0.12306 sex, age, array, PCs 1-10 —
PPM037461 PGS019279
(TPMI_476_SBayesR)
 PSS013181|
East Asian Ancestry|
17,583 individuals
 PGP000835 |
Chen HH et al. Nature (2025)
 Reported Trait: Allergic rhinitis — AUROC: 0.66246 R²: 0.12377 sex, age, array, PCs 1-10 —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000120 Cancer diagnoses were obtained from reigstry data in GERA, and ICD-9/10 codes mapped to ICD-O-3 codes in UK Biobank. Cancers for this phenotype were classified using the following SEER site recode(s): 20010, 20020, 20030, 20040, 20050, 20060, 20070, 20080, 20090, and 20100 —
[
  • 1,223 cases
  • , 410,354 controls
]
,
46.0 % Male samples
 Mean = 58.0 years European — GERA, UKB —
PSS013181 477,J30 —
[
  • 2,157 cases
  • , 15,426 controls
]
,
45.95 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013174 473, 784.91,J32, R09.82 —
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS007756 — — 2,469 individuals — African American or Afro-Caribbean Carribean UKB —
PSS008637 — — 6,611 individuals — European Italy (South Europe) UKB —
PSS008411 — — 1,182 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009309 — — 19,770 individuals — European UK (+ Ireland) UKB —
PSS004702 — —
[
  • 4 cases
  • , 6,493 controls
]
 — African unspecified — UKB —
PSS004703 — —
[
  • 53 cases
  • , 24,852 controls
]
 — European non-white British ancestry UKB —
PSS004704 — —
[
  • 20 cases
  • , 7,811 controls
]
 — South Asian — UKB —
PSS004705 — —
[
  • 156 cases
  • , 67,269 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004069 — —
[
  • 648 cases
  • , 5,849 controls
]
 — African unspecified — UKB —
PSS004070 — —
[
  • 330 cases
  • , 1,374 controls
]
 — East Asian — UKB —
PSS004071 — —
[
  • 2,149 cases
  • , 22,756 controls
]
 — European non-white British ancestry UKB —
PSS004072 — —
[
  • 893 cases
  • , 6,938 controls
]
 — South Asian — UKB —
PSS004073 — —
[
  • 6,545 cases
  • , 60,880 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS011948 — —
[
  • 2,393 cases
  • , 2,411 controls
]
 — East Asian — EPI-NPC-2005, NPCGEE —
PSS012283 — —
[
  • 231 cases
  • , 37,670 controls
]
 — European, African American or Afro-Caribbean — PMB —
PSS012284 — —
[
  • 556 cases
  • , 306,739 controls
]
 — European — UKB —
PSS012978 382,H66, H67 —
[
  • 175 cases
  • , 19,346 controls
]
,
46.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012979 382,H66, H67 —
[
  • 175 cases
  • , 19,346 controls
]
,
46.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS009083 — — 4,097 individuals — European Poland (NE Europe) UKB —
PSS012980 382,H66, H67 —
[
  • 175 cases
  • , 19,346 controls
]
,
46.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012981 382,H66, H67 —
[
  • 175 cases
  • , 19,346 controls
]
,
46.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012982 382,H66, H67 —
[
  • 175 cases
  • , 19,346 controls
]
,
46.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS008191 — — 6,238 individuals — South Asian India (South Asia) UKB —
PSS012984 386.0,H81.0, H81.31, H81.39 —
[
  • 398 cases
  • , 17,181 controls
]
,
47.0 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012983 386.0,H81.0, H81.31, H81.39 —
[
  • 398 cases
  • , 17,181 controls
]
,
47.0 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012985 386.0,H81.0, H81.31, H81.39 —
[
  • 398 cases
  • , 17,181 controls
]
,
47.0 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012986 386.0,H81.0, H81.31, H81.39 —
[
  • 398 cases
  • , 17,181 controls
]
,
47.0 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012987 386.0,H81.0, H81.31, H81.39 —
[
  • 398 cases
  • , 17,181 controls
]
,
47.0 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS009646 — —
[
  • 1,304 cases
  • , 1,589 controls
]
 — East Asian — NR —
PSS012998 386.3, 386.4, 386.5, 386.8,H81, H82, H83.0, H83.1, H83.2 —
[
  • 814 cases
  • , 17,181 controls
]
,
46.79 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012999 386.3, 386.4, 386.5, 386.8,H81, H82, H83.0, H83.1, H83.2 —
[
  • 814 cases
  • , 17,181 controls
]
,
46.79 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013000 386.3, 386.4, 386.5, 386.8,H81, H82, H83.0, H83.1, H83.2 —
[
  • 814 cases
  • , 17,181 controls
]
,
46.79 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013001 386.3, 386.4, 386.5, 386.8,H81, H82, H83.0, H83.1, H83.2 —
[
  • 814 cases
  • , 17,181 controls
]
,
46.79 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013002 386.3, 386.4, 386.5, 386.8,H81, H82, H83.0, H83.1, H83.2 —
[
  • 814 cases
  • , 17,181 controls
]
,
46.79 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012367 147,C11 —
[
  • 211 cases
  • , 18,859 controls
]
,
45.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012368 147,C11 —
[
  • 211 cases
  • , 18,859 controls
]
,
45.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012369 147,C11 —
[
  • 211 cases
  • , 18,859 controls
]
,
45.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012370 147,C11 —
[
  • 211 cases
  • , 18,859 controls
]
,
45.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS012371 147,C11 —
[
  • 211 cases
  • , 18,859 controls
]
,
45.15 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013009 386, 780.4,H81, H82, H83.0, H83.1, H83.2, H83.9, R42 —
[
  • 2,051 cases
  • , 17,181 controls
]
,
46.3 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS010150 — —
[
  • 26 cases
  • , 389 controls
]
 — European — UKB —
PSS013008 386, 780.4,H81, H82, H83.0, H83.1, H83.2, H83.9, R42 —
[
  • 2,051 cases
  • , 17,181 controls
]
,
46.3 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013010 386, 780.4,H81, H82, H83.0, H83.1, H83.2, H83.9, R42 —
[
  • 2,051 cases
  • , 17,181 controls
]
,
46.3 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS011364 — — 56,192 individuals — European — UKB —
PSS013011 386, 780.4,H81, H82, H83.0, H83.1, H83.2, H83.9, R42 —
[
  • 2,051 cases
  • , 17,181 controls
]
,
46.3 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013012 386, 780.4,H81, H82, H83.0, H83.1, H83.2, H83.9, R42 —
[
  • 2,051 cases
  • , 17,181 controls
]
,
46.3 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS004511 — —
[
  • 393 cases
  • , 6,104 controls
]
 — African unspecified — UKB —
PSS004512 — —
[
  • 215 cases
  • , 1,489 controls
]
 — East Asian — UKB —
PSS004513 — —
[
  • 1,438 cases
  • , 23,467 controls
]
 — European non-white British ancestry UKB —
PSS004514 — —
[
  • 435 cases
  • , 7,396 controls
]
 — South Asian — UKB —
PSS004515 — —
[
  • 4,398 cases
  • , 63,027 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS013172 473, 784.91,J32, R09.82 —
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013173 473, 784.91,J32, R09.82 —
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS001020 Individuals with at least one recorded incident diagnosis of a borderline, in situ, or malignant primary cancer were defined as cases. —
[
  • 481 cases
  • , 390,998 controls
]
 — European — UKB —
PSS013175 473, 784.91,J32, R09.82 —
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013176 473, 784.91,J32, R09.82 —
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013177 477,J30 —
[
  • 2,157 cases
  • , 15,426 controls
]
,
45.95 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013178 477,J30 —
[
  • 2,157 cases
  • , 15,426 controls
]
,
45.95 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013179 477,J30 —
[
  • 2,157 cases
  • , 15,426 controls
]
,
45.95 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —
PSS013180 477,J30 —
[
  • 2,157 cases
  • , 15,426 controls
]
,
45.95 % Male samples
 — East Asian
(Han Chinese)		 — TPMI —