Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS004318
(PRS29_dementia)
PGP000548 |
Feng J et al. BMC Geriatr (2023)
Dementia dementia 29
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004318/ScoringFiles/PGS004318.txt.gz
PGS004896
(mAlb)
PGP000623 |
Cañadas-Garre M et al. Int J Mol Sci (2023)
Microalbuminuria Moderate albuminuria 29
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004896/ScoringFiles/PGS004896.txt.gz
PGS000154
(cGRS_Colorectal)
PGP000075 |
Shi Z et al. Cancer Med (2019)
Colorectal cancer colorectal cancer 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000154/ScoringFiles/PGS000154.txt.gz
PGS000351
(PRS_EOC)
PGP000117 |
Barnes DR et al. Genet Med (2020)
Invasive epithelial ovarian cancer ovarian carcinoma 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000351/ScoringFiles/PGS000351.txt.gz
PGS000456
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 30
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000456/ScoringFiles/PGS000456.txt.gz
PGS000457
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 30
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000457/ScoringFiles/PGS000457.txt.gz
PGS000862
(DR)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Diabetic Retinopathy diabetic retinopathy 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000862/ScoringFiles/PGS000862.txt.gz
PGS001136
(GBE_HC413)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Hematologic disease, genetic hematologic disease 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001136/ScoringFiles/PGS001136.txt.gz
PGS001868
(portability-PLR_654.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Rhesus isoimmunization in pregnancy Rh isoimmunization 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001868/ScoringFiles/PGS001868.txt.gz
PGS004255
(GenoBoost_rheumatoid_arthritis_0)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Rheumatoid arthritis rheumatoid arthritis 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004255/ScoringFiles/PGS004255.txt.gz
PGS004280
(GenoBoost_all-cause_dementia_0)
PGP000546 |
Ohta R et al. Nat Commun (2024)
All-cause dementia dementia 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004280/ScoringFiles/PGS004280.txt.gz
PGS004287
(GenoBoost_alzheimer_s_disease_2)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Alzheimer's disease Alzheimer disease 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004287/ScoringFiles/PGS004287.txt.gz
PGS004322
(GRS30_IS)
PGP000555 |
McElligott B et al. Front Cardiovasc Med (2023)
Ischemic stroke stroke,
Ischemic stroke
30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004322/ScoringFiles/PGS004322.txt.gz
PGS005115
(PGS_T2D_beta_cell)
PGP000701 |
Loesch DP et al. medRxiv (2024)
|Pre
Type 2 diabetes (T2D) type 2 diabetes mellitus 30
-
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005115/ScoringFiles/PGS005115.txt.gz
PGS000197
(G-PROB_SpA)
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Spondyloarthroparthy spondyloarthropathy 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000197/ScoringFiles/PGS000197.txt.gz
PGS000198
(G-PROB_PsA)
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Psoriatic arthritis psoriatic arthritis 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000198/ScoringFiles/PGS000198.txt.gz
PGS000305
(GRS31_FG)
PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
Fasting glucose fasting blood glucose measurement 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000305/ScoringFiles/PGS000305.txt.gz
PGS000573
(PRSWEB_PHECODE185_C61_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Prostate cancer prostate carcinoma 31
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000573/ScoringFiles/PGS000573.txt.gz
PGS000599
(PRSWEB_PHECODE187.2_C3-TESTIS_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of testis testicular carcinoma 31
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000599/ScoringFiles/PGS000599.txt.gz
PGS000724
(PRS_Ovary)
PGP000135 |
Jia G et al. JNCI Cancer Spectr (2020)
Epithelial ovarian cancer ovarian carcinoma 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000724/ScoringFiles/PGS000724.txt.gz
PGS000744
(PRS_melanoma_pigment.pathway)
PGP000151 |
Cust AE et al. J Invest Dermatol (2018)
Melanoma melanoma 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000744/ScoringFiles/PGS000744.txt.gz
PGS000876
(PRS31_AD)
PGP000222 |
Leonenko G et al. Ann Clin Transl Neurol (2019)
Alzheimer's disease Alzheimer disease 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000876/ScoringFiles/PGS000876.txt.gz
PGS004907
(PRS31_FT4)
PGP000639 |
Mulder TA et al. Eur J Endocrinol (2023)
Free thyroxine concentration thyroxine measurement 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004907/ScoringFiles/PGS004907.txt.gz
PGS000063
(GRS_TG)
PGP000045 |
Johnson L et al. PLoS One (2015)
Triglycerides triglyceride measurement 32
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000063/ScoringFiles/PGS000063.txt.gz
PGS000119
(BCC32)
PGP000055 |
Fritsche LG et al. PLoS Genet (2019)
Basal cell carcinoma basal cell carcinoma 32
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000119/ScoringFiles/PGS000119.txt.gz
PGS000476
(PRSWEB_PHECODE174.1_C3-BREAST-3_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000476/ScoringFiles/PGS000476.txt.gz
PGS000646
(PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Chronic lymphocytic leukemia chronic lymphocytic leukemia 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000646/ScoringFiles/PGS000646.txt.gz
PGS000647
(PRSWEB_PHECODE204.12_GWAS-Catalog-r2019-05-03-X204.12_P_5e-08_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Chronic lymphocytic leukemia chronic lymphocytic leukemia 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000647/ScoringFiles/PGS000647.txt.gz
PGS000665
(GRS_32)
PGP000125 |
Marston NA et al. Circulation (2020)
Ischemic stroke stroke,
Ischemic stroke
32
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000665/ScoringFiles/PGS000665.txt.gz
PGS000756
(GRS3_Nar)
PGP000162 |
Ouyang H et al. Ann Transl Med (2020)
Narcolepsy narcolepsy-cataplexy syndrome 32
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000756/ScoringFiles/PGS000756.txt.gz
PGS003830
(TC_SAS_CT)
PGP000489 |
Zhang H et al. Nat Genet (2023)
Total cholesterol total cholesterol measurement 32
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003830/ScoringFiles/PGS003830.txt.gz
PGS004597
(PRS32_IS)
PGP000576 |
Peng H et al. Nutrients (2023)
Ischemic stroke stroke,
Ischemic stroke
32
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004597/ScoringFiles/PGS004597.txt.gz
PGS000021
(GRS1)
PGP000011 |
Oram RA et al. Diabetes Care (2015)
Type 1 diabetes (T1D) type 1 diabetes mellitus 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000021/ScoringFiles/PGS000021.txt.gz
PGS000026
(PHS)
PGP000016 |
Desikan RS et al. PLoS Med (2017)
Alzheimer's disease Alzheimer disease 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000026/ScoringFiles/PGS000026.txt.gz
PGS000122
(2018_BMD33_GRS.FN)
PGP000056 |
Ho-Le TP et al. J Bone Miner Res (2016)
Bone mineral density (BMD) bone density 33
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000122/ScoringFiles/PGS000122.txt.gz
PGS000341
(GRS33_SSc)
PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
Systemic sclerosis systemic scleroderma 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000341/ScoringFiles/PGS000341.txt.gz
PGS001827
(portability-PLR_290.1)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Dementia dementia 33
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001827/ScoringFiles/PGS001827.txt.gz
PGS002270
(PRS33_LC)
PGP000300 |
Zhang P et al. Br J Cancer (2022)
Lung cancer lung carcinoma 33
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002270/ScoringFiles/PGS002270.txt.gz
PGS002307
(PRS33_gout)
PGP000329 |
Zhang Y et al. BMC Med (2022)
Gout gout 33
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002307/ScoringFiles/PGS002307.txt.gz
PGS000859
(CKD)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Chronic kidney disease chronic kidney disease 34
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000859/ScoringFiles/PGS000859.txt.gz
PGS002730
(GRSlipid_35)
PGP000337 |
Mayerhofer E et al. Brain (2022)
LDL lowering in response to statin low density lipoprotein cholesterol measurement,
response to statin
35
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002730/ScoringFiles/PGS002730.txt.gz
PGS004106
(pt_clump.auto.GCST004773.T2D)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Type 2 diabetes (T2D) type 2 diabetes mellitus 35
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004106/ScoringFiles/PGS004106.txt.gz
PGS004238
(wGRS35)
PGP000535 |
Cheng CF et al. J Gene Med (2021)
Cardiovascular disease cardiovascular disease 35
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004238/ScoringFiles/PGS004238.txt.gz
PGS000082
(CC_Ovary)
PGP000050 |
Graff RE et al. Nat Commun (2021)
Ovarian cancer ovarian carcinoma 36
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000082/ScoringFiles/PGS000082.txt.gz
PGS000793
(CC_Ovary_IV)
PGP000186 |
Kachuri L et al. Nat Commun (2020)
Ovarian cancer ovarian carcinoma 36
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000793/ScoringFiles/PGS000793.txt.gz
PGS000875
(PGS36_LDLc)
PGP000221 |
Leal LG et al. Mol Genet Genomic Med (2020)
LDL cholesterol low density lipoprotein cholesterol measurement 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000875/ScoringFiles/PGS000875.txt.gz
PGS001025
(GBE_HC951)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Nonrheumatic aortic valve disorders (time-to-event) aortic valve disease 36
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001025/ScoringFiles/PGS001025.txt.gz
PGS001271
(GBE_HC810)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Multiple sclerosis (time-to-event) multiple sclerosis 36
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001271/ScoringFiles/PGS001271.txt.gz
PGS001287
(GBE_HC91)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Psoriatic arthropathy psoriatic arthritis 36
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001287/ScoringFiles/PGS001287.txt.gz
PGS002235
(elasticnet_VTE)
PGP000267 |
Kolin DA et al. Sci Rep (2021)
Venous thromboembolism venous thromboembolism 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002235/ScoringFiles/PGS002235.txt.gz