Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003585
(SoftImpOnly.LifetimeMDD)
 PGP000461 |
Dahl A et al. bioRxiv (2022)
|Pre		 Major Depressive Disorder (Lifetime) major depressive disorder 5,776,312
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003585/ScoringFiles/PGS003585.txt.gz
PGS004780
(height_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Height body height 5,967,476
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004780/ScoringFiles/PGS004780.txt.gz
PGS002725
(GIGASTROKE_iPGS_EAS)
 PGP000333 |
Mishra A et al. Nature (2022)
 Ischemic stroke stroke,
Ischemic stroke		 6,010,730
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002725/ScoringFiles/PGS002725.txt.gz
PGS004832
(sbp_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Systolic blood pressure systolic blood pressure 6,013,177
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004832/ScoringFiles/PGS004832.txt.gz
PGS004848
(tg_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Triglycerides triglyceride measurement 6,127,766
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004848/ScoringFiles/PGS004848.txt.gz
PGS004728
(Basophils_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Basophil count basophil count 6,132,012
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004728/ScoringFiles/PGS004728.txt.gz
PGS004730
(Basophils_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Basophil count basophil count 6,132,012
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004730/ScoringFiles/PGS004730.txt.gz
PGS004812
(Platelets_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Platelet count platelet count 6,146,883
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004812/ScoringFiles/PGS004812.txt.gz
PGS004814
(Platelets_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Platelet count platelet count 6,146,883
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004814/ScoringFiles/PGS004814.txt.gz
PGS004844
(tc_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Total cholesterol total cholesterol measurement 6,149,012
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004844/ScoringFiles/PGS004844.txt.gz
PGS000331
(PRS_AF)
 PGP000100 |
Mars N et al. Nat Med (2020)
 Atrial fibrillation atrial fibrillation 6,183,494
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000331/ScoringFiles/PGS000331.txt.gz
PGS003327
(ExPRSweb_Insomnia_1200_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Insomnia insomnia 6,214,923
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003327/ScoringFiles/PGS003327.txt.gz
PGS004846
(tg_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Triglycerides triglyceride measurement 6,248,300
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004846/ScoringFiles/PGS004846.txt.gz
PGS003082
(ExPRSweb_SBP_93-irnt_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Systolic blood pressure systolic blood pressure 6,341,932
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003082/ScoringFiles/PGS003082.txt.gz
PGS004690
(kidney_cancer)
 PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
 Kidney cancer renal carcinoma 6,351,669
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004690/ScoringFiles/PGS004690.txt.gz
PGS004693
(pancreatic_cancer)
 PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
 Pancreatic cancer pancreatic carcinoma 6,351,686
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004693/ScoringFiles/PGS004693.txt.gz
PGS004692
(ovarian_cancer)
 PGP000596 |
Hu J et al. JNCI Cancer Spectr (2024)
 Ovarian cancer ovarian carcinoma 6,385,666
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004692/ScoringFiles/PGS004692.txt.gz
PGS000332
(PRS_BC)
 PGP000100 |
Mars N et al. Nat Med (2020)
 Breast cancer breast carcinoma 6,390,808
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000332/ScoringFiles/PGS000332.txt.gz
PGS000329
(PRS_CHD)
 PGP000100 |
Mars N et al. Nat Med (2020)
 Coronary heart disease coronary artery disease 6,423,165
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000329/ScoringFiles/PGS000329.txt.gz
PGS002243
(ldpred_t2d)
 PGP000271 |
Mars N et al. Cell Genom (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,431,973
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002243/ScoringFiles/PGS002243.txt.gz
PGS004794
(ldl_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 6,433,913
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004794/ScoringFiles/PGS004794.txt.gz
PGS000330
(PRS_T2D)
 PGP000100 |
Mars N et al. Nat Med (2020)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,437,380
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000330/ScoringFiles/PGS000330.txt.gz
PGS004842
(tc_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Total cholesterol total cholesterol measurement 6,439,132
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004842/ScoringFiles/PGS004842.txt.gz
PGS004776
(hdl_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 HDL cholesterol high density lipoprotein cholesterol measurement 6,463,324
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004776/ScoringFiles/PGS004776.txt.gz
PGS004778
(hdl_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 HDL cholesterol high density lipoprotein cholesterol measurement 6,463,324
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004778/ScoringFiles/PGS004778.txt.gz
PGS004746
(cad_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Coronary artery disease coronary artery disease 6,483,064
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004746/ScoringFiles/PGS004746.txt.gz
PGS002242
(ldpred_breastcancer)
 PGP000271 |
Mars N et al. Cell Genom (2022)
 Breast cancer breast carcinoma 6,494,889
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002242/ScoringFiles/PGS002242.txt.gz
PGS002241
(ldpred_prostatecancer)
 PGP000271 |
Mars N et al. Cell Genom (2022)
 Prostate cancer prostate carcinoma 6,497,734
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002241/ScoringFiles/PGS002241.txt.gz
PGS003052
(ExPRSweb_Smoking_20116-2_DBSLMM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Smoking status smoking status measurement 6,575,783
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003052/ScoringFiles/PGS003052.txt.gz
PGS002244
(ldpred_cad)
 PGP000271 |
Mars N et al. Cell Genom (2022)
 Coronary artery disease coronary artery disease 6,576,338
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002244/ScoringFiles/PGS002244.txt.gz
PGS004792
(ldl_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 6,580,710
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004792/ScoringFiles/PGS004792.txt.gz
PGS004868
(T2DPGS)
 PGP000617 |
Yun JS et al. Cardiovasc Diabetol (2022)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,580,804
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004868/ScoringFiles/PGS004868.txt.gz
PGS004818
(RA_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Rheumatoid Arthritis rheumatoid arthritis 6,580,837
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004818/ScoringFiles/PGS004818.txt.gz
PGS004820
(RA_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Rheumatoid Arthritis rheumatoid arthritis 6,580,837
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004820/ScoringFiles/PGS004820.txt.gz
PGS004838
(t2d_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004838/ScoringFiles/PGS004838.txt.gz
PGS004840
(t2d_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 6,586,458
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004840/ScoringFiles/PGS004840.txt.gz
PGS004856
(WBC_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 White blood cell count leukocyte quantity 6,594,323
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004856/ScoringFiles/PGS004856.txt.gz
PGS004858
(WBC_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 White blood cell count leukocyte quantity 6,594,323
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004858/ScoringFiles/PGS004858.txt.gz
PGS000333
(PRS_PC)
 PGP000100 |
Mars N et al. Nat Med (2020)
 Prostate cancer prostate carcinoma 6,606,785
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000333/ScoringFiles/PGS000333.txt.gz
PGS003407
(2_withUKB_sexMale_metaGRS.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm,
male		 6,618,190
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003407/ScoringFiles/PGS003407.txt.gz
PGS003410
(5_withUKB_sexMale_IAonly.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm,
male		 6,618,190
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003410/ScoringFiles/PGS003410.txt.gz
PGS004786
(HTN_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Hypertension hypertension 6,622,611
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004786/ScoringFiles/PGS004786.txt.gz
PGS004788
(HTN_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Hypertension hypertension 6,622,611
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004788/ScoringFiles/PGS004788.txt.gz
PGS000013
(GPS_CAD)
 PGP000006 |
Khera AV et al. Nat Genet (2018)
 Coronary artery disease coronary artery disease 6,630,150
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000013/ScoringFiles/PGS000013.txt.gz - Check Terms/Licenses
PGS000296
(GPS_CAD_SA)
 PGP000090 |
Wang M et al. J Am Coll Cardiol (2020)
 Coronary artery disease coronary artery disease 6,630,150
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000296/ScoringFiles/PGS000296.txt.gz - Check Terms/Licenses
PGS004702
(a1c_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 HbA1c HbA1c measurement 6,652,699
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004702/ScoringFiles/PGS004702.txt.gz
PGS004704
(a1c_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 HbA1c HbA1c measurement 6,652,699
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004704/ScoringFiles/PGS004704.txt.gz
PGS003408
(3_withUKB_sexFemale_metaGRS.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm,
female		 6,671,269
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003408/ScoringFiles/PGS003408.txt.gz
PGS003411
(6_withUKB_sexFemale_IAonly.weights)
 PGP000423 |
Bakker MK et al. Stroke (2023)
 Intracranial aneurysm brain aneurysm,
female		 6,671,269
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003411/ScoringFiles/PGS003411.txt.gz
PGS003723
(cEF)
 PGP000465 |
Hatoum AS et al. Biol Psychiatry (2022)
 Common executive function executive function measurement 6,683,248
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003723/ScoringFiles/PGS003723.txt.gz
Showing 5001 to 5050 of 5134 rows