Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004238
(wGRS35)
 PGP000535 |
Cheng CF et al. J Gene Med (2021)
 Cardiovascular disease cardiovascular disease 35
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004238/ScoringFiles/PGS004238.txt.gz
PGS000082
(CC_Ovary)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Ovarian cancer ovarian carcinoma 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000082/ScoringFiles/PGS000082.txt.gz
PGS000793
(CC_Ovary_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Ovarian cancer ovarian carcinoma 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000793/ScoringFiles/PGS000793.txt.gz
PGS000875
(PGS36_LDLc)
 PGP000221 |
Leal LG et al. Mol Genet Genomic Med (2020)
 LDL cholesterol low density lipoprotein cholesterol measurement 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000875/ScoringFiles/PGS000875.txt.gz
PGS001025
(GBE_HC951)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Nonrheumatic aortic valve disorders (time-to-event) aortic valve disease 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001025/ScoringFiles/PGS001025.txt.gz
PGS001271
(GBE_HC810)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Multiple sclerosis (time-to-event) multiple sclerosis 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001271/ScoringFiles/PGS001271.txt.gz
PGS001287
(GBE_HC91)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Psoriatic arthropathy psoriatic arthritis 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001287/ScoringFiles/PGS001287.txt.gz
PGS002235
(elasticnet_VTE)
 PGP000267 |
Kolin DA et al. Sci Rep (2021)
 Venous thromboembolism venous thromboembolism 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002235/ScoringFiles/PGS002235.txt.gz
PGS002292
(PRS36_KC)
 PGP000321 |
He W et al. JAMA Ophthalmol (2022)
 Keratoconus keratoconus 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002292/ScoringFiles/PGS002292.txt.gz
PGS003394
(PRS_Stepwise)
 PGP000277 |
Dareng EO et al. Eur J Hum Genet (2022)
 Epithelial ovarian cancer ovarian carcinoma 36
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003394/ScoringFiles/PGS003394.txt.gz
PGS000022
(T1D_GRS)
 PGP000012 |
Perry DJ et al. Sci Rep (2018)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 37
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000022/ScoringFiles/PGS000022.txt.gz
PGS000061
(GRS_LDL)
 PGP000045 |
Johnson L et al. PLoS One (2015)
 Low-density lipoprotein (LDL) cholesterol low density lipoprotein cholesterol measurement 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000061/ScoringFiles/PGS000061.txt.gz
PGS000851
(T2D_Insulin_Action_Secretion)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action/secretion) type 2 diabetes mellitus 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000851/ScoringFiles/PGS000851.txt.gz
PGS002750
(PRS37_THR)
 PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
 Total hip replacement total hip arthroplasty,
osteoarthritis, hip		 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002750/ScoringFiles/PGS002750.txt.gz
PGS001036
(GBE_INI23004)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Epstein Barr virus nuclear antigen 1 IgG seropositivity Epstein Barr virus nuclear antigen-1 seropositivity 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001036/ScoringFiles/PGS001036.txt.gz
PGS001828
(portability-PLR_290.11)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Alzheimer's disease Alzheimer disease 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001828/ScoringFiles/PGS001828.txt.gz
PGS001835
(portability-PLR_364.5)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Corneal dystrophy corneal dystrophy 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001835/ScoringFiles/PGS001835.txt.gz
PGS002950
(ExPRSweb_Glucose_MAGIC-FastingGlucose_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Glucose blood glucose amount 38
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002950/ScoringFiles/PGS002950.txt.gz
PGS002951
(ExPRSweb_Glucose_MAGIC-FastingGlucose_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Glucose blood glucose amount 38
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002951/ScoringFiles/PGS002951.txt.gz
PGS004903
(PRS_ALL)
 PGP000633 |
Al-Janabi A et al. J Allergy Clin Immunol (2023)
 Atopic dermatitis atopic eczema 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004903/ScoringFiles/PGS004903.txt.gz
PGS000811
(AD-PRS_39)
 PGP000196 |
Najar J et al. Alzheimers Dement (Amst) (2021)
 Alzheimer's disease Alzheimer disease 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000811/ScoringFiles/PGS000811.txt.gz
PGS000842
(WHR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Waist-hip ratio waist-hip ratio 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000842/ScoringFiles/PGS000842.txt.gz
PGS001072
(GBE_BIN_FC20001757)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Facial aging, looking 'older than you are' aging rate 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001072/ScoringFiles/PGS001072.txt.gz
PGS001775
(PRS39_AD)
 PGP000255 |
Ebenau JL et al. Alzheimers Dement (Amst) (2021)
 Alzheimer's disease Alzheimer disease 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001775/ScoringFiles/PGS001775.txt.gz
PGS003969
(PRS39_HF)
 PGP000511 |
Rasooly D et al. Nat Commun (2023)
 Heart failure heart failure 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003969/ScoringFiles/PGS003969.txt.gz
PGS004588
(PRS39_Eur)
 PGP000567 |
Jung SH et al. JAMA Netw Open (2022)
 Alzheimer's disease Alzheimer disease 39
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004588/ScoringFiles/PGS004588.txt.gz
PGS000601
(PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of testis testicular carcinoma 40
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000601/ScoringFiles/PGS000601.txt.gz
PGS000602
(PRSWEB_PHECODE187.2_GWAS-Catalog-r2019-05-03-X187.2_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Malignant neoplasm of testis testicular carcinoma 40
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000602/ScoringFiles/PGS000602.txt.gz
PGS000801
(GRS40_CRC)
 PGP000190 |
Hang D et al. Int J Epidemiol (2020)
 Colorectal cancer colorectal cancer 40
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000801/ScoringFiles/PGS000801.txt.gz
PGS000898
(PRS39_AD)
 PGP000231 |
de Rojas I et al. Nat Commun (2021)
 Alzheimer's disease Alzheimer disease 40
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000898/ScoringFiles/PGS000898.txt.gz
PGS003813
(logTG_SAS_CT)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Log triglycerides triglyceride measurement 40
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003813/ScoringFiles/PGS003813.txt.gz
PGS003854
(PRS40_TG)
 PGP000493 |
Li J et al. JAMA Netw Open (2023)
 Triglycerides triglyceride measurement 40
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003854/ScoringFiles/PGS003854.txt.gz
PGS004274
(GenoBoost_inflammatory_bowel_disease_4)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Inflammatory bowel disease inflammatory bowel disease 40
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004274/ScoringFiles/PGS004274.txt.gz
PGS004282
(GenoBoost_all-cause_dementia_2)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 All-cause dementia dementia 40
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004282/ScoringFiles/PGS004282.txt.gz
PGS004289
(GenoBoost_alzheimer_s_disease_4)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Alzheimer's disease Alzheimer disease 40
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004289/ScoringFiles/PGS004289.txt.gz
PGS000149
(CRC41)
 PGP000072 |
Smith T et al. Br J Cancer (2018)
 Colorectal cancer colorectal cancer 41
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000149/ScoringFiles/PGS000149.txt.gz
PGS000374
(PRSWEB_PHECODE153_UKBB-SAIGE-HRC-X153_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colorectal cancer colorectal cancer 41
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000374/ScoringFiles/PGS000374.txt.gz
PGS000513
(PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 41
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000513/ScoringFiles/PGS000513.txt.gz
PGS000803
(wGRS41_SLE)
 PGP000192 |
Kawai VK et al. Lupus (2021)
 Systemic lupus erythematosus systemic lupus erythematosus 41
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000803/ScoringFiles/PGS000803.txt.gz
PGS000874
(PRS41_CLL)
 PGP000220 |
Kleinstern G et al. Blood (2018)
 Chronic lymphocytic leukemia chronic lymphocytic leukemia 41
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000874/ScoringFiles/PGS000874.txt.gz
PGS001270
(GBE_HC151)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Multiple sclerosis multiple sclerosis 41
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001270/ScoringFiles/PGS001270.txt.gz
PGS004892
(TNBC_PRS41)
 PGP000620 |
Sun X et al. Cancer Res (2024)
 Triple negative breast cancer triple-negative breast cancer 41
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004892/ScoringFiles/PGS004892.txt.gz
PGS000482
(PRSWEB_PHECODE174.1_C50_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 42
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000482/ScoringFiles/PGS000482.txt.gz
PGS000589
(PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Prostate cancer prostate carcinoma 42
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000589/ScoringFiles/PGS000589.txt.gz
PGS000760
(VIT)
 PGP000164 |
Khan Z et al. Nat Commun (2021)
 Vitiligo Vitiligo 42
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000760/ScoringFiles/PGS000760.txt.gz
PGS001326
(GBE_HC431)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Emphysema emphysema 42
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001326/ScoringFiles/PGS001326.txt.gz
PGS003295
(ExPRSweb_CysC_eGFRcys-overall-EA_PT_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 42
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003295/ScoringFiles/PGS003295.txt.gz
PGS003397
(PRS-42ASN)
 PGP000415 |
Jee YH et al. Int J Epidemiol (2022)
 Breast cancer breast carcinoma 42
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003397/ScoringFiles/PGS003397.txt.gz
PGS005163
(PRS-LC)
 PGP000711 |
Zhu M et al. PLoS Med (2025)
 Lung cancer lung carcinoma 42
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005163/ScoringFiles/PGS005163.txt.gz
PGS000304
(GRS43_HbA1c)
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 HbA1c HbA1c measurement 43
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000304/ScoringFiles/PGS000304.txt.gz
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