Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS000897
(GLGC_2021_SAS_LDL_PRS_weights_PT)
PGP000230 |
Graham SE et al. Nature (2021)
LDL cholesterol low density lipoprotein cholesterol measurement 13
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000897/ScoringFiles/PGS000897.txt.gz
PGS002925
(ExPRSweb_FPG_FGovertime-corrected_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Fasting plasma glucose fasting blood glucose measurement 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002925/ScoringFiles/PGS002925.txt.gz
PGS002926
(ExPRSweb_FPG_FGovertime-corrected_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Fasting plasma glucose fasting blood glucose measurement 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002926/ScoringFiles/PGS002926.txt.gz
PGS003040
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PT_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Polyunsatturated fatty acids polyunsaturated fatty acid measurement 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003040/ScoringFiles/PGS003040.txt.gz
PGS003041
(ExPRSweb_PUFAs_MAGNETIC-otPUFA_PLINK_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Polyunsatturated fatty acids polyunsaturated fatty acid measurement 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003041/ScoringFiles/PGS003041.txt.gz
PGS003736
(PRS13_BlC)
PGP000470 |
Xin J et al. EBioMedicine (2023)
Bladder cancer urinary bladder cancer 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003736/ScoringFiles/PGS003736.txt.gz
PGS004108
(pt_clump.auto.GCST005838.Stroke)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Stroke stroke 13
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004108/ScoringFiles/PGS004108.txt.gz
PGS004222
(GRS13_gout)
PGP000522 |
Wu Q et al. J Psychosom Res (2023)
Gout gout 13
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004222/ScoringFiles/PGS004222.txt.gz
PGS000081
(CC_Oral)
PGP000050 |
Graff RE et al. Nat Commun (2021)
Oral cavity and pharyngeal cancers oral cavity cancer,
pharynx cancer
14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000081/ScoringFiles/PGS000081.txt.gz
PGS000151
(SC_GRS)
PGP000074 |
Xin J et al. Gene (2018)
Colorectal cancer colorectal cancer 14
-
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000151/ScoringFiles/PGS000151.txt.gz
PGS000353
(PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Any cancer cancer 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000353/ScoringFiles/PGS000353.txt.gz
PGS000391
(PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Lung and bronchus cancer tracheal cancer,
bronchus cancer,
lung cancer
14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000391/ScoringFiles/PGS000391.txt.gz
PGS000464
(PRSWEB_PHECODE172.22_GWAS-Catalog-r2019-05-03-X172.22_PT_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Squamous cell carcinoma squamous cell carcinoma 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000464/ScoringFiles/PGS000464.txt.gz
PGS000522
(PRSWEB_PHECODE174.1_iCOGS-ER-negative-BRCA_PT_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Breast cancer (female) breast carcinoma 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000522/ScoringFiles/PGS000522.txt.gz
PGS000723
(PRS_Bladder)
PGP000135 |
Jia G et al. JNCI Cancer Spectr (2020)
Bladder cancer urinary bladder carcinoma 14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000723/ScoringFiles/PGS000723.txt.gz
PGS000731
(PRS_SCC)
PGP000138 |
Fontanillas P et al. Nat Commun (2021)
Squamous cell carcinoma squamous cell carcinoma 14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000731/ScoringFiles/PGS000731.txt.gz - Check Terms/Licenses
PGS000755
(PRS_SUA)
PGP000161 |
Cho SK et al. Sci Rep (2020)
Serum uric acid levels uric acid measurement 14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000755/ScoringFiles/PGS000755.txt.gz
PGS000767
(GRS14)
PGP000174 |
Guffanti G et al. Transl Psychiatry (2019)
Depression unipolar depression,
depressive symptom measurement
14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000767/ScoringFiles/PGS000767.txt.gz
PGS000792
(CC_Oral_IV)
PGP000186 |
Kachuri L et al. Nat Commun (2020)
Oral cavity and pharyngeal cancers oral cavity cancer,
pharynx cancer
14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000792/ScoringFiles/PGS000792.txt.gz
PGS000871
(IS_14)
PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
Insulin secretion insulin secretion measurement 14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000871/ScoringFiles/PGS000871.txt.gz
PGS002298
(PRS14_esophageal)
PGP000328 |
Choi J et al. Int J Cancer (2020)
Esophageal cancer esophageal carcinoma 14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002298/ScoringFiles/PGS002298.txt.gz
PGS002751
(GRSrare)
PGP000363 |
Sapkota Y et al. Nat Med (2022)
Body mass index (BMI) body mass index 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002751/ScoringFiles/PGS002751.txt.gz
PGS003419
(PRState_Trans)
PGP000430 |
Pagadala MS et al. BMC Cancer (2022)
Prostate cancer prostate cancer 14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003419/ScoringFiles/PGS003419.txt.gz
PGS003447
(PRS14_endo)
PGP000447 |
Kloeve-Mogensen K et al. Front Reprod Health (2021)
Endometriosis endometriosis 14
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003447/ScoringFiles/PGS003447.txt.gz
PGS003744
(PRS14_RC)
PGP000470 |
Xin J et al. EBioMedicine (2023)
Renal cancer renal carcinoma 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003744/ScoringFiles/PGS003744.txt.gz
PGS004239
(PRS14AAD)
PGP000538 |
Aranda-Guillén M et al. J Intern Med (2023)
Autoimmune Addison's disease chronic primary adrenal insufficiency 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004239/ScoringFiles/PGS004239.txt.gz
PGS004922
(wGRS_AFR)
PGP000655 |
El-Boraie A et al. Clin Pharmacol Ther (2021)
Nicotine metabolite ratio nicotine metabolite ratio 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004922/ScoringFiles/PGS004922.txt.gz
PGS000037
(PGS_AST)
PGP000025 |
Belsky DW et al. Lancet Respir Med (2013)
Asthma asthma 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000037/ScoringFiles/PGS000037.txt.gz
PGS000068
(PRS_EOC)
PGP000048 |
Yang X et al. J Med Genet (2018)
Epithelial ovarian cancer ovarian carcinoma 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000068/ScoringFiles/PGS000068.txt.gz
PGS000069
(PRS_sEOC)
PGP000048 |
Yang X et al. J Med Genet (2018)
Serous epithelial ovarian cancer ovarian serous carcinoma 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000069/ScoringFiles/PGS000069.txt.gz
PGS000071
(CC_Bladder)
PGP000050 |
Graff RE et al. Nat Commun (2021)
Bladder cancer urinary bladder carcinoma 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000071/ScoringFiles/PGS000071.txt.gz
PGS000355
(PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Any cancer cancer 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000355/ScoringFiles/PGS000355.txt.gz
PGS000431
(PRSWEB_PHECODE172.1_UKBB-SAIGE-HRC-X172.1_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Melanomas of skin (diagnosis or history) melanoma 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000431/ScoringFiles/PGS000431.txt.gz
PGS000555
(PRSWEB_PHECODE184.11_Phelan-LSASBOC_PT_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of ovary ovarian neoplasm 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000555/ScoringFiles/PGS000555.txt.gz
PGS000613
(PRSWEB_PHECODE189.2_GWAS-Catalog-r2019-05-03-X189.2_PT_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Bladder cancer urinary bladder carcinoma 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000613/ScoringFiles/PGS000613.txt.gz
PGS000722
(PRS_Kidney)
PGP000135 |
Jia G et al. JNCI Cancer Spectr (2020)
Kidney cancer renal carcinoma 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000722/ScoringFiles/PGS000722.txt.gz
PGS000782
(CC_Bladder_IV)
PGP000186 |
Kachuri L et al. Nat Commun (2020)
Bladder cancer urinary bladder carcinoma 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000782/ScoringFiles/PGS000782.txt.gz
PGS001348
(GBE_HC1584)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Alzheimer's disease (algorithmically-defined) Alzheimer disease 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001348/ScoringFiles/PGS001348.txt.gz
PGS001778
(PRS15_BC)
PGP000259 |
Yiangou K et al. Cancers (Basel) (2021)
Breast cancer breast carcinoma 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001778/ScoringFiles/PGS001778.txt.gz
PGS002283
(GRS15_NAFLD)
PGP000312 |
Schnurr TM et al. Hepatol Commun (2022)
Nonalcoholic fatty liver disease non-alcoholic fatty liver disease 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002283/ScoringFiles/PGS002283.txt.gz
PGS003181
(ExPRSweb_VitD_100021-raw_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Vitamin D vitamin D measurement 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003181/ScoringFiles/PGS003181.txt.gz
PGS003186
(ExPRSweb_VitD_29343764-GCST005367_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Vitamin D vitamin D measurement 15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003186/ScoringFiles/PGS003186.txt.gz
PGS003305
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PT_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003305/ScoringFiles/PGS003305.txt.gz
PGS003306
(ExPRSweb_CysC_CKDGen-1000Genomes-DiscoveryMeta-eGFRcys_PLINK_UKB_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate
15
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003306/ScoringFiles/PGS003306.txt.gz
PGS003448
(PRS15_ALL)
PGP000448 |
Berndt SI et al. Leukemia (2022)
Acute lymphoblastic leukemia acute lymphoblastic leukemia 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003448/ScoringFiles/PGS003448.txt.gz
PGS003717
(R_subiculum_body_UKBB_EUR_GWAS)
PGP000464 |
Liu N et al. Nat Genet (2023)
Right subiculum body volume subiculum volume 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003717/ScoringFiles/PGS003717.txt.gz
PGS004227
(ad_apoe_gw_pgs)
PGP000527 |
Green RE et al. Alzheimers Res Ther (2023)
Alzheimer's disease Alzheimer disease 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004227/ScoringFiles/PGS004227.txt.gz
PGS000123
(2017_PD16)
PGP000059 |
Ibanez L et al. BMC Neurol (2017)
Parkinson's disease Parkinson disease 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000123/ScoringFiles/PGS000123.txt.gz
PGS000412
(PRSWEB_PHECODE172.1_C3-MELANOMA-SKIN_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Melanomas of skin (diagnosis or history) melanoma 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000412/ScoringFiles/PGS000412.txt.gz
PGS000549
(PRSWEB_PHECODE184.11_Phelan-IEOC_P_5e-08_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of ovary ovarian neoplasm 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000549/ScoringFiles/PGS000549.txt.gz