Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS000638
(PRSWEB_PHECODE201_GWAS-Catalog-r2019-05-03-X201_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Hodgkin's disease Hodgkins lymphoma 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000638/ScoringFiles/PGS000638.txt.gz
PGS000769
(PRS16_BDR)
PGP000176 |
Sordillo JE et al. J Pers Med (2021)
Response to bronchodilator (albutamol) response to bronchodilator 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000769/ScoringFiles/PGS000769.txt.gz
PGS000850
(T2D_Insulin_Action)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with insulin action) type 2 diabetes mellitus 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000850/ScoringFiles/PGS000850.txt.gz
PGS000959
(GBE_HC136)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Connective tissue disorder connective tissue disease 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000959/ScoringFiles/PGS000959.txt.gz
PGS000976
(GBE_BIN23066)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
JCV seropositivity for Human Polyomavirus JCV polyomavirus 2 seropositivity 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000976/ScoringFiles/PGS000976.txt.gz
PGS002278
(GRS16_snLVEF)
PGP000307 |
Forrest IS et al. Eur J Heart Fail (2022)
Supranormal left ventricular ejection fraction left ventricular ejection fraction measurement 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002278/ScoringFiles/PGS002278.txt.gz
PGS003185
(ExPRSweb_VitD_29343764-GCST005367_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Vitamin D vitamin D measurement 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003185/ScoringFiles/PGS003185.txt.gz
PGS003421
(PRS16_C+T)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitis ankylosing spondylitis 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003421/ScoringFiles/PGS003421.txt.gz
PGS003422
(PRS16_PRSice2)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitis ankylosing spondylitis 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003422/ScoringFiles/PGS003422.txt.gz
PGS003740
(PRS16_CU)
PGP000470 |
Xin J et al. EBioMedicine (2023)
Corpus Uteri uterine corpus cancer 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003740/ScoringFiles/PGS003740.txt.gz
PGS004164
(PRS16_LC)
PGP000518 |
Wei X et al. Int J Cancer (2023)
Lung cancer in never smokers lung carcinoma,
smoking status measurement
16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004164/ScoringFiles/PGS004164.txt.gz
PGS004244
(PRS16_endometrium)
PGP000542 |
Kim ES et al. NPJ Precis Oncol (2023)
Endometrial cancer endometrial carcinoma 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004244/ScoringFiles/PGS004244.txt.gz
PGS004320
(PRS16_UGI)
PGP000551 |
Liu W et al. Nutrients (2023)
Upper gastrointestinal cancer Digestive System Carcinoma 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004320/ScoringFiles/PGS004320.txt.gz
PGS000048
(OCPRS_Overall)
PGP000033 |
Kuchenbaecker KB et al. J Natl Cancer Inst (2017)
Ovarian cancer ovarian carcinoma 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000048/ScoringFiles/PGS000048.txt.gz
PGS000129
(GS-E-EAS)
PGP000064 |
Wheeler E et al. PLoS Med (2017)
HbA1c HbA1c measurement 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000129/ScoringFiles/PGS000129.txt.gz
PGS000157
(cGRS_Melanoma)
PGP000075 |
Shi Z et al. Cancer Med (2019)
Melanoma melanoma 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000157/ScoringFiles/PGS000157.txt.gz
PGS000385
(PRSWEB_PHECODE157_GWAS-Catalog-r2019-05-03-X157_P_5e-08_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Pancreatic cancer pancreatic carcinoma 17
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000385/ScoringFiles/PGS000385.txt.gz
PGS001522
(GBE_HC1213)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Psoriatic and enteropathic arthropathies (time-to-event) Arthropathy 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001522/ScoringFiles/PGS001522.txt.gz
PGS002731
(oA-PRS)
PGP000339 |
Xicota L et al. Neurology (2022)
Alzheimer's disease Alzheimer disease 17
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002731/ScoringFiles/PGS002731.txt.gz
PGS002733
(GRS17_T2D)
PGP000342 |
Pezzilli S et al. Diabetes Metab (2022)
Type 2 diabetes (T2D) type 2 diabetes mellitus 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002733/ScoringFiles/PGS002733.txt.gz
PGS004591
(PRS17_MDD)
PGP000570 |
Li D et al. BMC Med (2023)
Major depressive disorder unipolar depression 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004591/ScoringFiles/PGS004591.txt.gz
PGS004601
(PRS17_Pca)
PGP000579 |
Wu Y et al. Clin Genet (2023)
Prostate cancer prostate carcinoma 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004601/ScoringFiles/PGS004601.txt.gz
PGS000371
(PRSWEB_PHECODE153_GWAS-Catalog-r2019-05-03-X153_P_5e-08_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Colorectal cancer colorectal cancer 18
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000371/ScoringFiles/PGS000371.txt.gz
PGS000421
(PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Melanomas of skin (diagnosis or history) melanoma 18
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000421/ScoringFiles/PGS000421.txt.gz
PGS000422
(PRSWEB_PHECODE172.1_GWAS-Catalog-r2019-05-03-X172.1_P_5e-08_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Melanomas of skin (diagnosis or history) melanoma 18
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000422/ScoringFiles/PGS000422.txt.gz
PGS000541
(PRSWEB_PHECODE182_GWAS-Catalog-r2019-05-03-X182_P_5e-08_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Malignant neoplasm of uterus uterine cancer 18
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000541/ScoringFiles/PGS000541.txt.gz
PGS000732
(PRS_Melanoma)
PGP000138 |
Fontanillas P et al. Nat Commun (2021)
Melanoma melanoma 18
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000732/ScoringFiles/PGS000732.txt.gz - Check Terms/Licenses
PGS000855
(T2D_Lipodystrophy)
PGP000211 |
Aly DM et al. Nat Genet (2021)
Type 2 diabetes (based on SNPs associated with lipodystrophy) type 2 diabetes mellitus 18
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000855/ScoringFiles/PGS000855.txt.gz
PGS000870
(CFRD_18)
PGP000214 |
Aksit MA et al. J Clin Endocrinol Metab (2020)
Cystic fibrosis related diabetes complication 18
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000870/ScoringFiles/PGS000870.txt.gz
PGS000880
(PRS18_LC)
PGP000226 |
Xie J et al. Sleep (2021)
Lung cancer lung carcinoma 18
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000880/ScoringFiles/PGS000880.txt.gz
PGS003335
(GRS18_BC)
PGP000404 |
Teleka S et al. Sci Rep (2022)
Bladder cancer urinary bladder carcinoma 18
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003335/ScoringFiles/PGS003335.txt.gz
PGS003489
(PRS_IL17)
PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
General atopic disease (IL-17 related variants) allergic disease 18
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003489/ScoringFiles/PGS003489.txt.gz
PGS003857
(GRS18_BMIunadj)
PGP000496 |
Sofer T et al. EBioMedicine (2023)
Obstructive sleep apnea obstructive sleep apnea 18
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003857/ScoringFiles/PGS003857.txt.gz
PGS000025
(GRS)
PGP000015 |
Chouraki V et al. J Alzheimers Dis (2016)
Alzheimer's disease Alzheimer disease 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000025/ScoringFiles/PGS000025.txt.gz
PGS000070
(PRS_LC_C)
PGP000049 |
Dai J et al. Lancet Respir Med (2019)
Lung cancer lung adenocarcinoma 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000070/ScoringFiles/PGS000070.txt.gz
PGS000076
(CC_Kidney)
PGP000050 |
Graff RE et al. Nat Commun (2021)
Kidney cancer renal cell carcinoma 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000076/ScoringFiles/PGS000076.txt.gz
PGS000080
(CC_NHL)
PGP000050 |
Graff RE et al. Nat Commun (2021)
Non-Hodgkin's lymphoma non-Hodgkins lymphoma 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000080/ScoringFiles/PGS000080.txt.gz
PGS000130
(GS-G-EUR)
PGP000064 |
Wheeler E et al. PLoS Med (2017)
HbA1c HbA1c measurement 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000130/ScoringFiles/PGS000130.txt.gz
PGS000131
(GS-G-AFR)
PGP000064 |
Wheeler E et al. PLoS Med (2017)
HbA1c HbA1c measurement 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000131/ScoringFiles/PGS000131.txt.gz
PGS000132
(GS-G-EAS)
PGP000064 |
Wheeler E et al. PLoS Med (2017)
HbA1c HbA1c measurement 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000132/ScoringFiles/PGS000132.txt.gz
PGS000155
(cGRS_Glioma)
PGP000075 |
Shi Z et al. Cancer Med (2019)
Glioma glioma 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000155/ScoringFiles/PGS000155.txt.gz
PGS000211
(PD19)
PGP000087 |
Pihlstrøm L et al. Mov Disord (2016)
Parkinson's disease Parkinson disease 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000211/ScoringFiles/PGS000211.txt.gz
PGS000306
(GRS19_FGadjBMI)
PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
Fasting glucose (body mass index adjusted) BMI-adjusted fasting blood glucose measurement 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000306/ScoringFiles/PGS000306.txt.gz
PGS000392
(PRSWEB_PHECODE165.1_GWAS-Catalog-r2019-05-03-X165.1_PT_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Lung and bronchus cancer tracheal cancer,
bronchus cancer,
lung cancer
19
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000392/ScoringFiles/PGS000392.txt.gz
PGS000445
(PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 19
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000445/ScoringFiles/PGS000445.txt.gz
PGS000619
(PRSWEB_PHECODE191.1_GWAS-Catalog-r2019-05-03-X191.1_PT_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Brain and nervous system cancer central nervous system cancer 19
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000619/ScoringFiles/PGS000619.txt.gz
PGS000721
(PRS_Lung)
PGP000135 |
Jia G et al. JNCI Cancer Spectr (2020)
Lung cancer lung carcinoma 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000721/ScoringFiles/PGS000721.txt.gz
PGS000787
(CC_Kidney_IV)
PGP000186 |
Kachuri L et al. Nat Commun (2020)
Kidney cancer renal cell carcinoma 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000787/ScoringFiles/PGS000787.txt.gz
PGS000791
(CC_NHL_IV)
PGP000186 |
Kachuri L et al. Nat Commun (2020)
Non-Hodgkin's lymphoma non-Hodgkins lymphoma 19
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000791/ScoringFiles/PGS000791.txt.gz
PGS000802
(CRC_19)
PGP000191 |
He CY et al. Genomics (2021)
Colorectal cancer colorectal cancer 19
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000802/ScoringFiles/PGS000802.txt.gz