Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003347
(ALLGRS_HDL)
 PGP000405 |
Kim YJ et al. Nat Commun (2022)
 HDL cholesterol high density lipoprotein cholesterol measurement 92
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003347/ScoringFiles/PGS003347.txt.gz
PGS003341
(CVGRS_TC)
 PGP000405 |
Kim YJ et al. Nat Commun (2022)
 Total cholesterol total cholesterol measurement 91
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003341/ScoringFiles/PGS003341.txt.gz
PGS004118
(pt_clump.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 91
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004118/ScoringFiles/PGS004118.txt.gz
PGS004323
(PRS91_T2D)
 PGP000557 |
Tan Q et al. J Hazard Mater (2023)
 Type 2 diabetes type 2 diabetes mellitus 91
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004323/ScoringFiles/PGS004323.txt.gz
PGS000038
(PRS90)
 PGP000026 |
Rutten-Jacobs LC et al. BMJ (2018)
 Stroke stroke 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000038/ScoringFiles/PGS000038.txt.gz
PGS000902
(PRS90_PD)
 PGP000235 |
Nalls MA et al. Lancet Neurol (2019)
 Parkinson's disease Parkinson disease 90
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000902/ScoringFiles/PGS000902.txt.gz
PGS001516
(GBE_HC1112)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Other diseases of intestine (time-to-event) intestinal disease 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001516/ScoringFiles/PGS001516.txt.gz
PGS003392
(best_LUSC)
 PGP000413 |
Namba S et al. Cancer Res (2022)
 Lung squamous cell carcinoma squamous cell lung carcinoma 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003392/ScoringFiles/PGS003392.txt.gz
PGS004283
(GenoBoost_all-cause_dementia_3)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 All-cause dementia dementia 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004283/ScoringFiles/PGS004283.txt.gz
PGS004297
(GenoBoost_breast_cancer_2)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Breast cancer breast carcinoma 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004297/ScoringFiles/PGS004297.txt.gz
PGS004924
(PRS90_PD)
 PGP000657 |
Cao Z et al. Parkinsonism Relat Disord (2023)
 Parkinson's disease Parkinson disease 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004924/ScoringFiles/PGS004924.txt.gz
PGS002267
(PRS89_AA)
 PGP000296 |
Pirruccello JP et al. Nat Genet (2021)
 Ascending thoracic aortic diameter cardiovascular disease biomarker measurement,
aortic measurement		 89
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002267/ScoringFiles/PGS002267.txt.gz
PGS004240
(PRS89_CRC)
 PGP000541 |
Fan L et al. Int J Cancer (2023)
 Colorectal cancer colorectal carcinoma 89
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004240/ScoringFiles/PGS004240.txt.gz
PGS005104
(PRSAFR)
 PGP000694 |
Jia G et al. Nat Genet (2024)
 Breast cancer breast carcinoma 89
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005104/ScoringFiles/PGS005104.txt.gz
PGS000045
(BCPRS_Overall)
 PGP000033 |
Kuchenbaecker KB et al. J Natl Cancer Inst (2017)
 Breast cancer breast carcinoma 88
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000045/ScoringFiles/PGS000045.txt.gz
PGS001280
(GBE_HC943)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 PE (time-to-event) pulmonary embolism 88
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001280/ScoringFiles/PGS001280.txt.gz
PGS004315
(GRS-ALL)
 PGP000547 |
Bui A et al. Front Genet (2023)
 Psoriasis psoriasis 88
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004315/ScoringFiles/PGS004315.txt.gz
PGS000046
(BCPRS_ER+)
 PGP000033 |
Kuchenbaecker KB et al. J Natl Cancer Inst (2017)
 Estrogen receptor [ER]-positive breast cancer estrogen-receptor positive breast cancer 87
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000046/ScoringFiles/PGS000046.txt.gz
PGS000370
(PRSWEB_PHECODE153_CRC-Huyghe_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colorectal cancer colorectal cancer 87
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000370/ScoringFiles/PGS000370.txt.gz
PGS001870
(portability-PLR_695.4)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Lupus (localized and systemic) lupus erythematosus 87
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001870/ScoringFiles/PGS001870.txt.gz
PGS003296
(ExPRSweb_CysC_eGFRcys-overall-EA_PLINK_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Cystatin C) cystatin C measurement,
glomerular filtration rate		 87
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003296/ScoringFiles/PGS003296.txt.gz
PGS003844
(bmi_AFR_CT)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Body mass index (BMI) body mass index 87
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003844/ScoringFiles/PGS003844.txt.gz
PGS004945
(PRS87_CRC)
 PGP000671 |
Gao P et al. Int J Cancer (2023)
 Colorectal cancer colorectal cancer 87
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004945/ScoringFiles/PGS004945.txt.gz
PGS000486
(PRSWEB_PHECODE174.1_GWAS-Catalog-r2019-05-03-X174.1_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 86
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000486/ScoringFiles/PGS000486.txt.gz
PGS000525
(PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 86
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000525/ScoringFiles/PGS000525.txt.gz
PGS000526
(PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_P_5e-08_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 86
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000526/ScoringFiles/PGS000526.txt.gz
PGS001532
(GBE_QT_FC10003466)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Time from waking to first cigarette smoking behavior trait 86
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001532/ScoringFiles/PGS001532.txt.gz
PGS000024
(GRS2)
 PGP000014 |
Sharp SA et al. Diabetes Care (2019)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 85
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000024/ScoringFiles/PGS000024.txt.gz
PGS000538
(PRSWEB_PHECODE174.1_iCOGS-Overall-BRCA_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 85
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000538/ScoringFiles/PGS000538.txt.gz
PGS001876
(portability-PLR_715.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ankylosing spondylitis ankylosing spondylitis 85
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001876/ScoringFiles/PGS001876.txt.gz
PGS003955
(AD_Jun)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 85
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003955/ScoringFiles/PGS003955.txt.gz
PGS000515
(PRSWEB_PHECODE174.1_UKBB-SAIGE-HRC-X174.1_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 84
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000515/ScoringFiles/PGS000515.txt.gz
PGS000661
(PRS-LDL)
 PGP000121 |
Tam CHT et al. Genome Med (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 84
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000661/ScoringFiles/PGS000661.txt.gz
PGS000028
(PRS)
 PGP000018 |
Shieh Y et al. Breast Cancer Res Treat (2016)
 Breast cancer breast carcinoma 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000028/ScoringFiles/PGS000028.txt.gz
PGS001703
(GBE_INI25730)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA ISOVF in tract uncinate fasciculus (R) neuroimaging measurement,
brain volume		 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001703/ScoringFiles/PGS001703.txt.gz
PGS002280
(GRS83_AD)
 PGP000309 |
Bellenguez C et al. Nat Genet (2022)
 Alzheimer's disease Alzheimer disease 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002280/ScoringFiles/PGS002280.txt.gz
PGS004104
(pt_clump.auto.GCST002783.BMI)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Body mass index (BMI) body mass index 83
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004104/ScoringFiles/PGS004104.txt.gz
PGS004600
(PRS_AD83)
 PGP000578 |
Tomassen J et al. BMC Neurol (2022)
 Alzheimer's disease Alzheimer disease 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004600/ScoringFiles/PGS004600.txt.gz
PGS001131
(GBE_HC530)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Zoster [herpes zoster] (time-to-event) Herpes Zoster 82
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001131/ScoringFiles/PGS001131.txt.gz
PGS001717
(GBE_INI25600)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA L2 in tract cingulate gyrus part of cingulum (L) neuroimaging measurement,
brain volume		 82
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001717/ScoringFiles/PGS001717.txt.gz
PGS002793
(PRS84_Pca)
 PGP000371 |
Ruan X et al. Prostate (2022)
 Prostate cancer prostate carcinoma 82
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002793/ScoringFiles/PGS002793.txt.gz
PGS003344
(CVGRS_GGT)
 PGP000405 |
Kim YJ et al. Nat Commun (2022)
 Gamma-glutamyl transferase serum gamma-glutamyl transferase measurement 82
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003344/ScoringFiles/PGS003344.txt.gz
PGS000369
(PRSWEB_PHECODE153_CRC-Huyghe_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colorectal cancer colorectal cancer 81
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000369/ScoringFiles/PGS000369.txt.gz
PGS003739
(PRS81_CoC)
 PGP000470 |
Xin J et al. EBioMedicine (2023)
 Colorectal cancer colorectal carcinoma 81
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003739/ScoringFiles/PGS003739.txt.gz
PGS003954
(AD_FINNGEN)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 81
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003954/ScoringFiles/PGS003954.txt.gz
PGS005206
(BMD_PRS)
 PGP000728 |
Prijatelj V et al. Bone (2024)
 Bone mineral density bone tissue density 81
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005206/ScoringFiles/PGS005206.txt.gz
PGS000125
(Qi_T2D_2017)
 PGP000062 |
Qi Q et al. Diabetes (2017)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 80
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000125/ScoringFiles/PGS000125.txt.gz
PGS000300
(GRS80_HR)
 PGP000092 |
Xie T et al. Circ Genom Precis Med (2020)
 Heart rate heart rate 80
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000300/ScoringFiles/PGS000300.txt.gz
PGS000404
(PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Skin cancer skin carcinoma 80
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000404/ScoringFiles/PGS000404.txt.gz
PGS000591
(PRSWEB_PHECODE185_UKBB-SAIGE-HRC-X185_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Prostate cancer prostate carcinoma 80
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000591/ScoringFiles/PGS000591.txt.gz
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