Trait: skin disease

Experimental Factor Ontology (EFO) Information
Identifier EFO_0000701
Description Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs. [NCIT: C3371]
Trait category
Other disease
Synonyms 14 synonyms
  • Cutaneous Disorder
  • SKIN AND SUBCUTANEOUS TISSUE DISORDERS
  • Skin Diseases and Manifestations
  • Skin Disorder
  • cutaneous disorder
  • disease of zone of skin
  • disease or disorder of zone of skin
  • disorder of skin
  • disorder of zone of skin
  • skin and subcutaneous tissue disease
  • skin diseases and manifestations
  • skin disorder
  • zone of skin disease
  • zone of skin disease or disorder
Mapped terms 15 mapped terms
  • DOID:37
  • ICD10:L08
  • ICD10:L30
  • ICD10:L53
  • ICD10:L91
  • ICD10:L98
  • ICD10:R21
  • ICD9:702
  • ICD9:702.8
  • ICD9:709.8
  • MESH:D012871
  • MONDO:0005093
  • NCIT:C3371
  • NCIt:C3371
  • SCTID:95320005
Child trait(s) 19 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "skin disease" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS000119
(BCC32)
PGP000055 |
Fritsche LG et al. PLoS Genet (2019)
Basal cell carcinoma basal cell carcinoma 32
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000119/ScoringFiles/PGS000119.txt.gz
PGS000339
(PRS22_CM)
PGP000106 |
Law MH et al. Hum Mol Genet (2020)
Cutaneous melanoma cutaneous melanoma 22
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000339/ScoringFiles/PGS000339.txt.gz
PGS000341
(GRS33_SSc)
PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
Systemic sclerosis systemic scleroderma 33
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000341/ScoringFiles/PGS000341.txt.gz
PGS000398
(PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 1,103,220
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000398/ScoringFiles/PGS000398.txt.gz
PGS000399
(PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 6
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000399/ScoringFiles/PGS000399.txt.gz
PGS000400
(PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 95
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000400/ScoringFiles/PGS000400.txt.gz
PGS000401
(PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000401/ScoringFiles/PGS000401.txt.gz
PGS000402
(PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 389
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000402/ScoringFiles/PGS000402.txt.gz
PGS000403
(PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 16,316
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000403/ScoringFiles/PGS000403.txt.gz
PGS000404
(PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 80
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000404/ScoringFiles/PGS000404.txt.gz
PGS000405
(PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 1,119,238
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000405/ScoringFiles/PGS000405.txt.gz
PGS000406
(PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 292
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000406/ScoringFiles/PGS000406.txt.gz
PGS000407
(PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Skin cancer skin carcinoma 3,166
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000407/ScoringFiles/PGS000407.txt.gz
PGS000433
(PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 108
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000433/ScoringFiles/PGS000433.txt.gz
PGS000434
(PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000434/ScoringFiles/PGS000434.txt.gz
PGS000435
(PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 446
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000435/ScoringFiles/PGS000435.txt.gz
PGS000436
(PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 16,626
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000436/ScoringFiles/PGS000436.txt.gz
PGS000437
(PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 63
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000437/ScoringFiles/PGS000437.txt.gz
PGS000438
(PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000438/ScoringFiles/PGS000438.txt.gz
PGS000439
(PRSWEB_PHECODE172.2_C44_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 467
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000439/ScoringFiles/PGS000439.txt.gz
PGS000440
(PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 2,111
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000440/ScoringFiles/PGS000440.txt.gz
PGS000441
(PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 77
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000441/ScoringFiles/PGS000441.txt.gz
PGS000442
(PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 1,119,238
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000442/ScoringFiles/PGS000442.txt.gz
PGS000443
(PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 177
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000443/ScoringFiles/PGS000443.txt.gz
PGS000444
(PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Other non-epithelial cancer of skin skin cancer 7,231
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000444/ScoringFiles/PGS000444.txt.gz
PGS000445
(PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 19
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000445/ScoringFiles/PGS000445.txt.gz
PGS000446
(PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 1,111,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000446/ScoringFiles/PGS000446.txt.gz
PGS000447
(PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 72
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000447/ScoringFiles/PGS000447.txt.gz
PGS000448
(PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 183
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000448/ScoringFiles/PGS000448.txt.gz
PGS000449
(PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 1,073,162
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000449/ScoringFiles/PGS000449.txt.gz
PGS000450
(PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000450/ScoringFiles/PGS000450.txt.gz
PGS000451
(PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 2,231
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000451/ScoringFiles/PGS000451.txt.gz
PGS000452
(PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000452/ScoringFiles/PGS000452.txt.gz
PGS000453
(PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000453/ScoringFiles/PGS000453.txt.gz
PGS000454
(PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000454/ScoringFiles/PGS000454.txt.gz
PGS000455
(PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 28
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000455/ScoringFiles/PGS000455.txt.gz
PGS000456
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 30
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000456/ScoringFiles/PGS000456.txt.gz
PGS000457
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 30
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000457/ScoringFiles/PGS000457.txt.gz
PGS000458
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 23
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000458/ScoringFiles/PGS000458.txt.gz
PGS000459
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Basal cell carcinoma basal cell carcinoma 24
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000459/ScoringFiles/PGS000459.txt.gz
PGS000469
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Carcinoma in situ of skin skin carcinoma in situ 1,119,238
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000469/ScoringFiles/PGS000469.txt.gz
PGS000470
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Carcinoma in situ of skin skin carcinoma in situ 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000470/ScoringFiles/PGS000470.txt.gz
PGS000471
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608)
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Carcinoma in situ of skin skin carcinoma in situ 7
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000471/ScoringFiles/PGS000471.txt.gz
PGS000730
(PRS_BCC)
PGP000138 |
Fontanillas P et al. Nat Commun (2021)
Basal cell carcinoma basal cell carcinoma 47
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000730/ScoringFiles/PGS000730.txt.gz - Check Terms/Licenses
PGS000738
(CONFIRMED_PGS)
PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
Vitiligo Vitiligo 48
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000738/ScoringFiles/PGS000738.txt.gz
PGS000760
(VIT)
PGP000164 |
Khan Z et al. Nat Commun (2021)
Vitiligo Vitiligo 42
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000760/ScoringFiles/PGS000760.txt.gz
PGS000766
(PRS56_CM)
PGP000172 |
Bakshi A et al. J Natl Cancer Inst (2021)
Cutaneous melanoma cutaneous melanoma 56
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000766/ScoringFiles/PGS000766.txt.gz
PGS000927
(GBE_HC1158)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Other dermatitis (time-to-event) dermatitis 242
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000927/ScoringFiles/PGS000927.txt.gz
PGS000944
(GBE_HC261)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Eczema, dermatitis Eczema,
dermatitis
598
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000944/ScoringFiles/PGS000944.txt.gz
PGS000963
(GBE_HC1184)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Follicular cysts of skin and subcutaneous tissue (time-to-event) Follicular Cyst 264
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000963/ScoringFiles/PGS000963.txt.gz
PGS001011
(GBE_HC534)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Viral warts (time-to-event) common wart 5
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001011/ScoringFiles/PGS001011.txt.gz
PGS001040
(GBE_cancer1060)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Non melanoma skin cancer non-melanoma skin carcinoma 1,610
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001040/ScoringFiles/PGS001040.txt.gz
PGS001041
(GBE_cancer1003)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Skin cancer skin carcinoma 1,298
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001041/ScoringFiles/PGS001041.txt.gz
PGS001131
(GBE_HC530)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Zoster [herpes zoster] (time-to-event) Herpes Zoster 82
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001131/ScoringFiles/PGS001131.txt.gz
PGS001140
(GBE_HC1190)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Seborrheic keratosis (time-to-event) seborrheic keratosis 1,368
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001140/ScoringFiles/PGS001140.txt.gz
PGS001257
(GBE_INI1737)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Childhood sunburn sunburn 519
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001257/ScoringFiles/PGS001257.txt.gz
PGS001312
(GBE_HC38)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Psoriasis psoriasis 204
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001312/ScoringFiles/PGS001312.txt.gz
PGS001313
(GBE_HC1159)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Psoriasis (time-to-event) psoriasis 578
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001313/ScoringFiles/PGS001313.txt.gz
PGS001536
(GBE_HC1188)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Vitiligo (time-to-event) Vitiligo 77
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001536/ScoringFiles/PGS001536.txt.gz
PGS001773
(PRS_atopicDermatitis)
PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
Moderate-to-severe atopic dermatitis atopic eczema 25
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001773/ScoringFiles/PGS001773.txt.gz
PGS001803
(portability-PLR_172)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Skin cancer skin carcinoma 4,371
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001803/ScoringFiles/PGS001803.txt.gz
PGS001869
(portability-PLR_681)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Superficial cellulitis and abscess cellulitis 131
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001869/ScoringFiles/PGS001869.txt.gz
PGS001871
(portability-PLR_696.4)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Psoriasis psoriasis 264
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001871/ScoringFiles/PGS001871.txt.gz
PGS001872
(portability-PLR_697)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sarcoidosis skin sarcoidosis 79
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001872/ScoringFiles/PGS001872.txt.gz
PGS001874
(portability-PLR_706.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sebaceous cyst Epidermal Inclusion Cyst 563
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001874/ScoringFiles/PGS001874.txt.gz
PGS002014
(portability-ldpred2_172)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Skin cancer skin carcinoma 534,399
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002014/ScoringFiles/PGS002014.txt.gz
PGS002081
(portability-ldpred2_681)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Superficial cellulitis and abscess cellulitis 640,921
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002081/ScoringFiles/PGS002081.txt.gz
PGS002083
(portability-ldpred2_696.4)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Psoriasis psoriasis 71,744
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002083/ScoringFiles/PGS002083.txt.gz
PGS002084
(portability-ldpred2_697)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sarcoidosis skin sarcoidosis 403,417
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002084/ScoringFiles/PGS002084.txt.gz
PGS002085
(portability-ldpred2_702.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Seborrheic keratosis seborrheic keratosis 481,233
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002085/ScoringFiles/PGS002085.txt.gz
PGS002087
(portability-ldpred2_706.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Sebaceous cyst Epidermal Inclusion Cyst 206,669
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002087/ScoringFiles/PGS002087.txt.gz
PGS002293
(PRS62_psoriasis)
PGP000323 |
Shen M et al. J Am Acad Dermatol (2022)
Psoriasis psoriasis 62
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002293/ScoringFiles/PGS002293.txt.gz
PGS002320
(disease_DERMATOLOGY.BOLT-LMM)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Dermatologic diseases skin disease 1,109,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002320/ScoringFiles/PGS002320.txt.gz
PGS002344
(disease_PSORIASIS.BOLT-LMM)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Psoriasis psoriasis 1,109,311
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002344/ScoringFiles/PGS002344.txt.gz
PGS002392
(disease_DERMATOLOGY.P+T.0.0001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Dermatologic diseases skin disease 3,539
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002392/ScoringFiles/PGS002392.txt.gz
PGS002416
(disease_PSORIASIS.P+T.0.0001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Psoriasis psoriasis 6,879
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002416/ScoringFiles/PGS002416.txt.gz
PGS002441
(disease_DERMATOLOGY.P+T.0.001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Dermatologic diseases skin disease 14,624
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002441/ScoringFiles/PGS002441.txt.gz
PGS002465
(disease_PSORIASIS.P+T.0.001)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Psoriasis psoriasis 21,483
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002465/ScoringFiles/PGS002465.txt.gz
PGS002490
(disease_DERMATOLOGY.P+T.0.01)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Dermatologic diseases skin disease 88,324
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002490/ScoringFiles/PGS002490.txt.gz
PGS002514
(disease_PSORIASIS.P+T.0.01)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Psoriasis psoriasis 96,453
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002514/ScoringFiles/PGS002514.txt.gz
PGS002539
(disease_DERMATOLOGY.P+T.1e-06)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Dermatologic diseases skin disease 540
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002539/ScoringFiles/PGS002539.txt.gz
PGS002563
(disease_PSORIASIS.P+T.1e-06)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Psoriasis psoriasis 1,348
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002563/ScoringFiles/PGS002563.txt.gz
PGS002588
(disease_DERMATOLOGY.P+T.5e-08)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Dermatologic diseases skin disease 240
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002588/ScoringFiles/PGS002588.txt.gz
PGS002612
(disease_PSORIASIS.P+T.5e-08)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Psoriasis psoriasis 643
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002612/ScoringFiles/PGS002612.txt.gz
PGS002637
(disease_DERMATOLOGY.PolyFun-pred)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Dermatologic diseases skin disease 164,178
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002637/ScoringFiles/PGS002637.txt.gz
PGS002661
(disease_PSORIASIS.PolyFun-pred)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Psoriasis psoriasis 283,128
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002661/ScoringFiles/PGS002661.txt.gz
PGS002686
(disease_DERMATOLOGY.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Dermatologic diseases skin disease 815,851
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002686/ScoringFiles/PGS002686.txt.gz
PGS002710
(disease_PSORIASIS.SBayesR)
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Psoriasis psoriasis 566,839
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002710/ScoringFiles/PGS002710.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000344 PGS000119
(BCC32)
PSS000207|
European Ancestry|
20,468 individuals
PGP000055 |
Fritsche LG et al. PLoS Genet (2019)
Reported Trait: Skin cancer OR: 1.32 [1.27, 1.36] AUROC: 0.58 [0.56, 0.58] age, sex, batch, PC1-4
PPM000341 PGS000119
(BCC32)
PSS000209|
European Ancestry|
20,468 individuals
PGP000055 |
Fritsche LG et al. PLoS Genet (2019)
Reported Trait: Basal cell carcinoma OR: 1.65 [1.56, 1.75] AUROC: 0.64 [0.62, 0.66] age, sex, batch, PC1-4
PPM000347 PGS000119
(BCC32)
PSS000211|
European Ancestry|
149,857 individuals
PGP000055 |
Fritsche LG et al. PLoS Genet (2019)
Reported Trait: Skin cancer OR: 1.4 [1.42, 1.48] age, sex, genotyping array, first 4 genotype PCs
PPM000922 PGS000339
(PRS22_CM)
PSS000464|
European Ancestry|
1,885 individuals
PGP000106 |
Law MH et al. Hum Mol Genet (2020)
Reported Trait: Cutaneous melanoma in multiplex melanoma families Difference of PRS (deltaPRS; unaffected melanoma family members vs. unrelated controls): 0.347 (0.104) PCs (1-10) *Sample overlap between the controls used in this analysis and score development
PPM000921 PGS000339
(PRS22_CM)
PSS000463|
European Ancestry|
3,066 individuals
PGP000106 |
Law MH et al. Hum Mol Genet (2020)
Reported Trait: Cutaneous melanoma in multiplex melanoma families Difference of PRS (deltaPRS; melanoma family cases vs. unrelated controls): 0.505 (0.036) PCs (1-10) *Sample overlap between the controls used in this analysis and score development
PPM000970 PGS000341
(GRS33_SSc)
PSS000489|
European Ancestry|
339 individuals
PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
Reported Trait: Systemic sclerosis AUROC: 0.787 [0.73, 0.84] Systemic sclerosis status, age and immune cell counts of: memory B cells, resting NK cells, M0 macrophages and activated dendritic cells *Some overlap with score development and testing samples
PPM000969 PGS000341
(GRS33_SSc)
PSS000489|
European Ancestry|
339 individuals
PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
Reported Trait: Systemic sclerosis AUROC: 0.722 Systemic sclerosis status and immune cell counts of: memory B cells, resting NK cells, M0 macrophages and activated dendritic cells *Some overlap with score development and testing samples
PPM000968 PGS000341
(GRS33_SSc)
PSS000489|
European Ancestry|
339 individuals
PGP000110 |
Bossini-Castillo L et al. Ann Rheum Dis (2020)
Reported Trait: Systemic sclerosis AUROC: 0.644 *Some overlap with score development and testing samples
PPM001083 PGS000398
(PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.042 [1.003, 1.082]
β: 0.0407 (0.0195)
AUROC: 0.51 [0.499, 0.521] Nagelkerke's Pseudo-R²: 0.00028
Brier score: 0.148
Odds Ratio (OR, top 1% vs. Rest): 1.7 [1.22, 2.38]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_20001-1003_PRS-CS_MGI_20200608
PPM001084 PGS000399
(PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.158 [1.116, 1.202]
β: 0.147 (0.0189)
AUROC: 0.513 [0.503, 0.523] Nagelkerke's Pseudo-R²: 0.00545
Brier score: 0.148
Odds Ratio (OR, top 1% vs. Rest): 1.56 [1.12, 2.16]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_20001-1003_PT_MGI_20200608
PPM001085 PGS000400
(PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.342 [1.291, 1.395]
β: 0.294 (0.0197)
AUROC: 0.581 [0.57, 0.592] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.2 [1.63, 2.98]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_P_5e-08_MGI_20200608
PPM001086 PGS000401
(PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.342 [1.291, 1.396]
β: 0.294 (0.0199)
AUROC: 0.581 [0.57, 0.591] Nagelkerke's Pseudo-R²: 0.0202
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.25 [1.67, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_PRS-CS_MGI_20200608
PPM001087 PGS000402
(PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.366 [1.314, 1.421]
β: 0.312 (0.0198)
AUROC: 0.586 [0.576, 0.597] Nagelkerke's Pseudo-R²: 0.0224
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.23 [1.64, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_PT_MGI_20200608
PPM001088 PGS000403
(PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.359 [1.307, 1.413]
β: 0.307 (0.0199)
AUROC: 0.584 [0.573, 0.594] Nagelkerke's Pseudo-R²: 0.0219
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 1.65 [1.2, 2.27]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_C3-SKIN_LASSOSUM_MGI_20200608
PPM001089 PGS000404
(PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.369 [1.317, 1.422]
β: 0.314 (0.0196)
AUROC: 0.584 [0.574, 0.594] Nagelkerke's Pseudo-R²: 0.0226
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.3 [1.72, 3.09]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_P_5e-08_MGI_20200608
PPM001090 PGS000405
(PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.338 [1.287, 1.391]
β: 0.291 (0.0199)
AUROC: 0.58 [0.57, 0.591] Nagelkerke's Pseudo-R²: 0.0192
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.42 [1.81, 3.24]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PRS-CS_MGI_20200608
PPM001091 PGS000406
(PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.392 [1.339, 1.447]
β: 0.331 (0.0199)
AUROC: 0.591 [0.581, 0.602] Nagelkerke's Pseudo-R²: 0.0249
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.51 [1.89, 3.34]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_PT_MGI_20200608
PPM001092 PGS000407
(PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608)
PSS000548|
European Ancestry|
17,607 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Skin cancer OR: 1.38 [1.328, 1.434]
β: 0.322 (0.0197)
AUROC: 0.586 [0.575, 0.597] Nagelkerke's Pseudo-R²: 0.0245
Brier score: 0.146
Odds Ratio (OR, top 1% vs. Rest): 2.26 [1.69, 3.03]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172_UKBB-SAIGE-HRC-X172_LASSOSUM_MGI_20200608
PPM001118 PGS000433
(PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.367 [1.31, 1.426]
β: 0.312 (0.0215)
AUROC: 0.584 [0.572, 0.598] Nagelkerke's Pseudo-R²: 0.0215
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.73 [2.01, 3.72]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_P_5e-08_MGI_20200608
PPM001119 PGS000434
(PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.361 [1.304, 1.42]
β: 0.308 (0.0217)
AUROC: 0.586 [0.573, 0.598] Nagelkerke's Pseudo-R²: 0.0208
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 1.99 [1.43, 2.78]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PRS-CS_MGI_20200608
PPM001120 PGS000435
(PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.357 [1.301, 1.415]
β: 0.305 (0.0215)
AUROC: 0.584 [0.572, 0.597] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.7 [1.99, 3.66]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_PT_MGI_20200608
PPM001121 PGS000436
(PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.361 [1.305, 1.42]
β: 0.308 (0.0216)
AUROC: 0.584 [0.571, 0.596] Nagelkerke's Pseudo-R²: 0.021
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.22 [1.61, 3.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C3-OTHER-SKIN_LASSOSUM_MGI_20200608
PPM001122 PGS000437
(PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.352 [1.296, 1.409]
β: 0.301 (0.0213)
AUROC: 0.579 [0.566, 0.592] Nagelkerke's Pseudo-R²: 0.0206
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.21 [1.6, 3.06]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_P_5e-08_MGI_20200608
PPM001123 PGS000438
(PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.31 [1.256, 1.367]
β: 0.27 (0.0216)
AUROC: 0.575 [0.562, 0.587] Nagelkerke's Pseudo-R²: 0.0162
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 1.79 [1.28, 2.51]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_PRS-CS_MGI_20200608
PPM001124 PGS000439
(PRSWEB_PHECODE172.2_C44_PT_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.348 [1.293, 1.407]
β: 0.299 (0.0216)
AUROC: 0.583 [0.57, 0.595] Nagelkerke's Pseudo-R²: 0.0197
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.17 [1.57, 3.01]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_PT_MGI_20200608
PPM001125 PGS000440
(PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.351 [1.296, 1.409]
β: 0.301 (0.0215)
AUROC: 0.581 [0.569, 0.592] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.55 [1.87, 3.46]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_C44_LASSOSUM_MGI_20200608
PPM001126 PGS000441
(PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.39 [1.333, 1.449]
β: 0.329 (0.0214)
AUROC: 0.586 [0.574, 0.599] Nagelkerke's Pseudo-R²: 0.0241
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.65 [1.94, 3.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_P_5e-08_MGI_20200608
PPM001127 PGS000442
(PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.357 [1.301, 1.417]
β: 0.306 (0.0217)
AUROC: 0.584 [0.572, 0.595] Nagelkerke's Pseudo-R²: 0.0201
Brier score: 0.137
Odds Ratio (OR, top 1% vs. Rest): 2.35 [1.71, 3.22]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PRS-CS_MGI_20200608
PPM001128 PGS000443
(PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.41 [1.352, 1.471]
β: 0.344 (0.0216)
AUROC: 0.591 [0.579, 0.603] Nagelkerke's Pseudo-R²: 0.0259
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 2.89 [2.14, 3.92]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608
PPM001129 PGS000444
(PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608)
PSS000546|
European Ancestry|
15,898 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Other non-epithelial cancer of skin OR: 1.399 [1.341, 1.46]
β: 0.336 (0.0216)
AUROC: 0.59 [0.578, 0.601] Nagelkerke's Pseudo-R²: 0.025
Brier score: 0.136
Odds Ratio (OR, top 1% vs. Rest): 3.5 [2.63, 4.65]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_LASSOSUM_MGI_20200608
PPM001130 PGS000445
(PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.334 [1.264, 1.409]
β: 0.289 (0.0278)
AUROC: 0.571 [0.555, 0.587] Nagelkerke's Pseudo-R²: 0.0184
Brier score: 0.108
Odds Ratio (OR, top 1% vs. Rest): 2.54 [1.72, 3.74]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_P_5e-08_MGI_20200608
PPM001131 PGS000446
(PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.291 [1.221, 1.366]
β: 0.256 (0.0286)
AUROC: 0.575 [0.559, 0.591] Nagelkerke's Pseudo-R²: 0.0139
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 1.42 [0.871, 2.33]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_PRS-CS_MGI_20200608
PPM001132 PGS000447
(PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.398 [1.322, 1.477]
β: 0.335 (0.0282)
AUROC: 0.591 [0.575, 0.607] Nagelkerke's Pseudo-R²: 0.0237
Brier score: 0.108
Odds Ratio (OR, top 1% vs. Rest): 2.5 [1.68, 3.71]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_PT_MGI_20200608
PPM001133 PGS000448
(PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.411 [1.335, 1.491]
β: 0.344 (0.0282)
AUROC: 0.587 [0.57, 0.604] Nagelkerke's Pseudo-R²: 0.0254
Brier score: 0.108
Odds Ratio (OR, top 1% vs. Rest): 2.93 [2.03, 4.25]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1061_LASSOSUM_MGI_20200608
PPM001134 PGS000449
(PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.093 [1.034, 1.155]
β: 0.0888 (0.0282)
AUROC: 0.525 [0.509, 0.54] Nagelkerke's Pseudo-R²: 0.00141
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 1.65 [1.04, 2.61]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_PRS-CS_MGI_20200608
PPM001135 PGS000450
(PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.079 [1.022, 1.139]
β: 0.0759 (0.0278)
AUROC: 0.504 [0.489, 0.52] Nagelkerke's Pseudo-R²: 0.00145
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 1.42 [0.882, 2.3]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_PT_MGI_20200608
PPM001136 PGS000451
(PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.144 [1.084, 1.208]
β: 0.135 (0.0278)
AUROC: 0.521 [0.506, 0.536] Nagelkerke's Pseudo-R²: 0.00396
Brier score: 0.109
Odds Ratio (OR, top 1% vs. Rest): 2.44 [1.65, 3.62]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_20001-1073_LASSOSUM_MGI_20200608
PPM001137 PGS000452
(PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.663 [1.57, 1.761]
β: 0.508 (0.0293)
AUROC: 0.632 [0.616, 0.647] Nagelkerke's Pseudo-R²: 0.0487
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 3.61 [2.53, 5.15]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_MGI_20200608
PPM001138 PGS000453
(PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608)
PSS000568|
European Ancestry|
60,018 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.511 [1.47, 1.554]
β: 0.413 (0.0142)
AUROC: 0.611 [0.604, 0.619] Nagelkerke's Pseudo-R²: 0.0301
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.8 [2.33, 3.36]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_P_5e-08_UKB_20200608
PPM001139 PGS000454
(PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.661 [1.568, 1.759]
β: 0.507 (0.0293)
AUROC: 0.632 [0.616, 0.647] Nagelkerke's Pseudo-R²: 0.0489
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 3.79 [2.68, 5.35]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_PT_MGI_20200608
PPM001140 PGS000455
(PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608)
PSS000568|
European Ancestry|
60,018 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.511 [1.47, 1.554]
β: 0.413 (0.0142)
AUROC: 0.611 [0.604, 0.619] Nagelkerke's Pseudo-R²: 0.0301
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 2.8 [2.33, 3.36]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_BCC-Chahal_PT_UKB_20200608
PPM001141 PGS000456
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.633 [1.541, 1.729]
β: 0.49 (0.0293)
AUROC: 0.63 [0.615, 0.646] Nagelkerke's Pseudo-R²: 0.0456
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 3.95 [2.79, 5.58]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_MGI_20200608
PPM001142 PGS000457
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608)
PSS000568|
European Ancestry|
60,018 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.535 [1.493, 1.579]
β: 0.429 (0.0144)
AUROC: 0.617 [0.609, 0.625] Nagelkerke's Pseudo-R²: 0.0322
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.11 [2.6, 3.71]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_P_5e-08_UKB_20200608
PPM001143 PGS000458
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608)
PSS000544|
European Ancestry|
11,322 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.634 [1.542, 1.732]
β: 0.491 (0.0296)
AUROC: 0.628 [0.612, 0.644] Nagelkerke's Pseudo-R²: 0.0457
Brier score: 0.106
Odds Ratio (OR, top 1% vs. Rest): 4.03 [2.86, 5.69]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_MGI_20200608
PPM001144 PGS000459
(PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608)
PSS000568|
European Ancestry|
60,018 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Basal cell carcinoma OR: 1.528 [1.485, 1.572]
β: 0.424 (0.0144)
AUROC: 0.615 [0.608, 0.623] Nagelkerke's Pseudo-R²: 0.0314
Brier score: 0.0813
Odds Ratio (OR, top 1% vs. Rest): 3.05 [2.55, 3.64]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.21_GWAS-Catalog-r2019-05-03-X172.21_PT_UKB_20200608
PPM001154 PGS000469
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608)
PSS000547|
European Ancestry|
5,500 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Carcinoma in situ of skin OR: 1.09 [1.001, 1.188]
β: 0.0865 (0.0437)
AUROC: 0.524 [0.499, 0.549] Nagelkerke's Pseudo-R²: 0.00141
Brier score: 0.0939
Odds Ratio (OR, top 1% vs. Rest): 1.48 [0.703, 3.1]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PRS-CS_MGI_20200608
PPM001155 PGS000470
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608)
PSS000547|
European Ancestry|
5,500 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Carcinoma in situ of skin OR: 1.308 [1.208, 1.417]
β: 0.269 (0.0407)
AUROC: 0.557 [0.531, 0.582] Nagelkerke's Pseudo-R²: 0.0154
Brier score: 0.093
Odds Ratio (OR, top 1% vs. Rest): 2.45 [1.34, 4.45]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_PT_MGI_20200608
PPM001156 PGS000471
(PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608)
PSS000547|
European Ancestry|
5,500 individuals
PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
Reported Trait: Carcinoma in situ of skin OR: 1.401 [1.297, 1.513]
β: 0.337 (0.0393)
AUROC: 0.569 [0.541, 0.595] Nagelkerke's Pseudo-R²: 0.0255
Brier score: 0.0923
Odds Ratio (OR, top 1% vs. Rest): 3.77 [2.24, 6.34]
age, sex, batch PCs 1-4 Cancer PRSweb PheWAS Results: PRSWEB_PHECODE172.3_UKBB-SAIGE-HRC-X172.3_LASSOSUM_MGI_20200608
PPM001670 PGS000730
(PRS_BCC)
PSS000871|
European Ancestry|
88,924 individuals
PGP000138 |
Fontanillas P et al. Nat Commun (2021)
Reported Trait: Basal cell carcinoma OR: 1.57 [1.55, 1.6] AUROC: 0.624
PPM001761 PGS000738
(CONFIRMED_PGS)
PSS000907|
European Ancestry|
4,008 individuals
PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
Reported Trait: Vitiligo Odds Ratio (OR, top 20% vs remaining 80% of score distribution): 4.87 [4.21, 5.64]
PPM001762 PGS000738
(CONFIRMED_PGS)
PSS000907|
European Ancestry|
4,008 individuals
PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
Reported Trait: Vitiligo Odds Ratio (OR, top 10% vs remaining 90% of score distribution): 5.26 [4.42, 6.29]
PPM001763 PGS000738
(CONFIRMED_PGS)
PSS000907|
European Ancestry|
4,008 individuals
PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
Reported Trait: Vitiligo Odds Ratio (OR, top 10% vs remaining 95% of score distribution): 6.2 [4.96, 7.79]
PPM001764 PGS000738
(CONFIRMED_PGS)
PSS000907|
European Ancestry|
4,008 individuals
PGP000145 |
Roberts GHL et al. Am J Hum Genet (2019)
Reported Trait: Vitiligo Odds Ratio (OR, top 1% vs remaining 99% of score distribution): 8.79 [5.85, 13.78]
PPM001935 PGS000760
(VIT)
PSS000970|
European Ancestry|
1,584 individuals
PGP000164 |
Khan Z et al. Nat Commun (2021)
Reported Trait: anti-PD-L1 induced hypothyroidism in cancer patients HR: 1.41 [1.22, 1.61] meta-analysis p-value: 1.10e-06 5 genotype PCs
PPM001963 PGS000766
(PRS56_CM)
PSS000982|
European Ancestry|
12,712 individuals
PGP000172 |
Bakshi A et al. J Natl Cancer Inst (2021)
Reported Trait: Incident cutaneous melanoma Hazard Ratio (HR, top 20% vs bottom 20%): 2.51 [1.28, 4.92] Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control.
PPM001964 PGS000766
(PRS56_CM)
PSS000982|
European Ancestry|
12,712 individuals
PGP000172 |
Bakshi A et al. J Natl Cancer Inst (2021)
Reported Trait: Incident cutaneous melanoma (males) Hazard Ratio (HR, top 20% vs bottom 20%): 3.7 [1.37, 9.98] Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control.
PPM001965 PGS000766
(PRS56_CM)
PSS000982|
European Ancestry|
12,712 individuals
PGP000172 |
Bakshi A et al. J Natl Cancer Inst (2021)
Reported Trait: Incident cutaneous melanoma (males) Hazard Ratio (HR, middle 60% vs bottom 20%): 2.61 [1.03, 6.63] Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control.
PPM001966 PGS000766
(PRS56_CM)
PSS000982|
European Ancestry|
12,712 individuals
PGP000172 |
Bakshi A et al. J Natl Cancer Inst (2021)
Reported Trait: Prevalent cutaneous melanoma OR: 1.55 [1.42, 1.69] AUROC: 0.64 [0.62, 0.66] Odds Ratio (OR, top 20% vs bottom 20%): 3.66 [2.69, 5.05] Sex, family history Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control.
PPM001967 PGS000766
(PRS56_CM)
PSS000982|
European Ancestry|
12,712 individuals
PGP000172 |
Bakshi A et al. J Natl Cancer Inst (2021)
Reported Trait: Prevalent cutaneous melanoma (males) OR: 1.39 [1.23, 1.57] Family history Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control.
PPM001968 PGS000766
(PRS56_CM)
PSS000982|
European Ancestry|
12,712 individuals
PGP000172 |
Bakshi A et al. J Natl Cancer Inst (2021)
Reported Trait: Prevalent cutaneous melanoma (females) OR: 1.72 [1.53, 1.94] Family history Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control.
PPM001962 PGS000766
(PRS56_CM)
PSS000982|
European Ancestry|
12,712 individuals
PGP000172 |
Bakshi A et al. J Natl Cancer Inst (2021)
Reported Trait: Incident cutaneous melanoma HR: 1.46 [1.2, 1.77] C-index: 0.643 [0.584, 0.702] Sex, melanoma family history, treatment (aspirin/placebo), age at enrolment, PRS*treatment Only 55 of the 56 SNPs within the PGS were utilised. Rs16891982 was not included as the SNP did not pass imputation quality control.
PPM007462 PGS000927
(GBE_HC1158)
PSS004153|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other dermatitis AUROC: 0.61027 [0.57953, 0.64101] : 0.02035
Incremental AUROC (full-covars): 0.00207
PGS R2 (no covariates): 0.00268
PGS AUROC (no covariates): 0.5378 [0.50673, 0.56886]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007463 PGS000927
(GBE_HC1158)
PSS004154|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other dermatitis AUROC: 0.57706 [0.52927, 0.62486] : 0.02951
Incremental AUROC (full-covars): 0.01147
PGS R2 (no covariates): 0.00458
PGS AUROC (no covariates): 0.5429 [0.49389, 0.59191]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007464 PGS000927
(GBE_HC1158)
PSS004155|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other dermatitis AUROC: 0.54587 [0.53304, 0.5587] : 0.00506
Incremental AUROC (full-covars): 0.01785
PGS R2 (no covariates): 0.00339
PGS AUROC (no covariates): 0.53939 [0.52639, 0.55239]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007465 PGS000927
(GBE_HC1158)
PSS004156|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other dermatitis AUROC: 0.58261 [0.56273, 0.60248] : 0.01573
Incremental AUROC (full-covars): 0.00482
PGS R2 (no covariates): 0.00187
PGS AUROC (no covariates): 0.52627 [0.50591, 0.54663]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007466 PGS000927
(GBE_HC1158)
PSS004157|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other dermatitis AUROC: 0.56752 [0.56014, 0.57491] : 0.01047
Incremental AUROC (full-covars): 0.01697
PGS R2 (no covariates): 0.00542
PGS AUROC (no covariates): 0.54889 [0.54154, 0.55624]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007546 PGS000944
(GBE_HC261)
PSS004384|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Eczema/dermatitis AUROC: 0.62856 [0.58377, 0.67334] : 0.02337
Incremental AUROC (full-covars): 0.00187
PGS R2 (no covariates): 0.00173
PGS AUROC (no covariates): 0.52778 [0.48039, 0.57516]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007547 PGS000944
(GBE_HC261)
PSS004385|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Eczema/dermatitis AUROC: 0.59588 [0.52553, 0.66622] : 0.02855
Incremental AUROC (full-covars): 0.02432
PGS R2 (no covariates): 0.0116
PGS AUROC (no covariates): 0.58664 [0.52213, 0.65115]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007548 PGS000944
(GBE_HC261)
PSS004386|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Eczema/dermatitis AUROC: 0.56459 [0.54541, 0.58377] : 0.00802
Incremental AUROC (full-covars): 0.01208
PGS R2 (no covariates): 0.00353
PGS AUROC (no covariates): 0.54597 [0.52632, 0.56561]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007549 PGS000944
(GBE_HC261)
PSS004387|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Eczema/dermatitis AUROC: 0.56106 [0.52439, 0.59773] : 0.00683
Incremental AUROC (full-covars): -0.0012
PGS R2 (no covariates): 0.00011
PGS AUROC (no covariates): 0.51686 [0.48122, 0.5525]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007550 PGS000944
(GBE_HC261)
PSS004388|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Eczema/dermatitis AUROC: 0.57099 [0.55943, 0.58256] : 0.00884
Incremental AUROC (full-covars): 0.02521
PGS R2 (no covariates): 0.00527
PGS AUROC (no covariates): 0.5556 [0.54396, 0.56724]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007639 PGS000963
(GBE_HC1184)
PSS004168|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue AUROC: 0.56399 [0.51489, 0.61308] : 0.01027
Incremental AUROC (full-covars): -0.00108
PGS R2 (no covariates): 0.00011
PGS AUROC (no covariates): 0.51899 [0.4747, 0.56328]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007640 PGS000963
(GBE_HC1184)
PSS004169|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue AUROC: 0.64299 [0.54406, 0.74191] : 0.02377
Incremental AUROC (full-covars): 0.01591
PGS R2 (no covariates): 0.00898
PGS AUROC (no covariates): 0.60189 [0.51478, 0.689]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007641 PGS000963
(GBE_HC1184)
PSS004170|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue AUROC: 0.61353 [0.59056, 0.63651] : 0.02635
Incremental AUROC (full-covars): 0.0691
PGS R2 (no covariates): 0.02281
PGS AUROC (no covariates): 0.59346 [0.56998, 0.61695]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007642 PGS000963
(GBE_HC1184)
PSS004171|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue AUROC: 0.64204 [0.6008, 0.68328] : 0.03504
Incremental AUROC (full-covars): 0.04562
PGS R2 (no covariates): 0.02125
PGS AUROC (no covariates): 0.56287 [0.51348, 0.61226]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007643 PGS000963
(GBE_HC1184)
PSS004172|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE follicular cysts of skin and subcutaneous tissue AUROC: 0.6146 [0.60131, 0.6279] : 0.02902
Incremental AUROC (full-covars): 0.06632
PGS R2 (no covariates): 0.02439
PGS AUROC (no covariates): 0.58761 [0.57398, 0.60124]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007818 PGS001011
(GBE_HC534)
PSS004521|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE viral warts AUROC: 0.62763 [0.56904, 0.68622] : 0.01913
Incremental AUROC (full-covars): -0.00455
PGS R2 (no covariates): 0.00116
PGS AUROC (no covariates): 0.48242 [0.41987, 0.54497]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007819 PGS001011
(GBE_HC534)
PSS004522|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE viral warts AUROC: 0.65545 [0.57671, 0.73418] : 0.03677
Incremental AUROC (full-covars): -0.00026
PGS R2 (no covariates): 1e-05
PGS AUROC (no covariates): 0.50846 [0.40705, 0.60986]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007820 PGS001011
(GBE_HC534)
PSS004523|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE viral warts AUROC: 0.56023 [0.54032, 0.58015] : 0.0051
Incremental AUROC (full-covars): 0.01103
PGS R2 (no covariates): 0.00154
PGS AUROC (no covariates): 0.53437 [0.51402, 0.55472]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007821 PGS001011
(GBE_HC534)
PSS004524|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE viral warts AUROC: 0.5793 [0.54592, 0.61268] : 0.01114
Incremental AUROC (full-covars): 0.00245
PGS R2 (no covariates): 0.00048
PGS AUROC (no covariates): 0.51036 [0.47743, 0.54328]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007822 PGS001011
(GBE_HC534)
PSS004525|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE viral warts AUROC: 0.56004 [0.54811, 0.57198] : 0.00576
Incremental AUROC (full-covars): 0.00636
PGS R2 (no covariates): 0.00167
PGS AUROC (no covariates): 0.53057 [0.51862, 0.54252]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007958 PGS001040
(GBE_cancer1060)
PSS007651|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Non-melanoma skin cancer AUROC: 0.80478 [0.72556, 0.884] : 0.07029
Incremental AUROC (full-covars): -0.00066
PGS R2 (no covariates): 0.00133
PGS AUROC (no covariates): 0.54127 [0.39017, 0.69237]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007959 PGS001040
(GBE_cancer1060)
PSS007652|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Non-melanoma skin cancer AUROC: 0.86455 [0.80574, 0.92335] : 0.12918
Incremental AUROC (full-covars): -0.00442
PGS R2 (no covariates): 0.00152
PGS AUROC (no covariates): 0.4523 [0.1694, 0.73519]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007960 PGS001040
(GBE_cancer1060)
PSS007653|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Non-melanoma skin cancer AUROC: 0.73342 [0.72065, 0.74619] : 0.10751
Incremental AUROC (full-covars): 0.0378
PGS R2 (no covariates): 0.05185
PGS AUROC (no covariates): 0.66327 [0.64889, 0.67765]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007961 PGS001040
(GBE_cancer1060)
PSS007654|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Non-melanoma skin cancer AUROC: 0.76366 [0.66832, 0.85901] : 0.06447
Incremental AUROC (full-covars): -0.00934
PGS R2 (no covariates): 0.00078
PGS AUROC (no covariates): 0.47181 [0.35611, 0.58752]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007962 PGS001040
(GBE_cancer1060)
PSS007655|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Non-melanoma skin cancer AUROC: 0.70656 [0.69863, 0.7145] : 0.08615
Incremental AUROC (full-covars): 0.04717
PGS R2 (no covariates): 0.03949
PGS AUROC (no covariates): 0.64209 [0.6334, 0.65078]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007963 PGS001041
(GBE_cancer1003)
PSS007621|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Skin cancer AUROC: 0.78777 [0.7126, 0.86293] : 0.06151
Incremental AUROC (full-covars): 0.00386
PGS R2 (no covariates): 0.00103
PGS AUROC (no covariates): 0.5229 [0.37426, 0.67153]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007964 PGS001041
(GBE_cancer1003)
PSS007622|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Skin cancer AUROC: 0.83061 [0.75233, 0.9089] : 0.10839
Incremental AUROC (full-covars): 0.0017
PGS R2 (no covariates): 0.00376
PGS AUROC (no covariates): 0.56985 [0.36492, 0.77477]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007965 PGS001041
(GBE_cancer1003)
PSS007623|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Skin cancer AUROC: 0.71667 [0.70431, 0.72902] : 0.09613
Incremental AUROC (full-covars): 0.03439
PGS R2 (no covariates): 0.04566
PGS AUROC (no covariates): 0.65086 [0.63722, 0.6645]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007966 PGS001041
(GBE_cancer1003)
PSS007624|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Skin cancer AUROC: 0.76232 [0.67332, 0.85131] : 0.07091
Incremental AUROC (full-covars): -0.01012
PGS R2 (no covariates): 6e-05
PGS AUROC (no covariates): 0.49291 [0.37897, 0.60686]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007967 PGS001041
(GBE_cancer1003)
PSS007625|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Skin cancer AUROC: 0.6935 [0.68584, 0.70116] : 0.07834
Incremental AUROC (full-covars): 0.04393
PGS R2 (no covariates): 0.03573
PGS AUROC (no covariates): 0.63289 [0.62459, 0.64118]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008383 PGS001131
(GBE_HC530)
PSS004516|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE zoster [herpes zoster] AUROC: 0.66564 [0.59848, 0.7328] : 0.02855
Incremental AUROC (full-covars): 0.00653
PGS R2 (no covariates): 0.00463
PGS AUROC (no covariates): 0.5717 [0.50786, 0.63553]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008384 PGS001131
(GBE_HC530)
PSS004517|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE zoster [herpes zoster] AUROC: 0.6496 [0.5711, 0.7281] : 0.02884
Incremental AUROC (full-covars): 0.00319
PGS R2 (no covariates): 1e-05
PGS AUROC (no covariates): 0.49296 [0.39896, 0.58695]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008385 PGS001131
(GBE_HC530)
PSS004518|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE zoster [herpes zoster] AUROC: 0.61339 [0.59385, 0.63293] : 0.01934
Incremental AUROC (full-covars): 0.00397
PGS R2 (no covariates): 0.00108
PGS AUROC (no covariates): 0.52734 [0.50543, 0.54926]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008386 PGS001131
(GBE_HC530)
PSS004519|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE zoster [herpes zoster] AUROC: 0.64482 [0.60407, 0.68558] : 0.02792
Incremental AUROC (full-covars): -0.00388
PGS R2 (no covariates): 0.00012
PGS AUROC (no covariates): 0.49268 [0.44738, 0.53799]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008387 PGS001131
(GBE_HC530)
PSS004520|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE zoster [herpes zoster] AUROC: 0.60947 [0.59775, 0.62119] : 0.0198
Incremental AUROC (full-covars): 0.00787
PGS R2 (no covariates): 0.00329
PGS AUROC (no covariates): 0.54558 [0.53361, 0.55755]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008427 PGS001140
(GBE_HC1190)
PSS004178|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE seborrhoeic keratosis AUROC: 0.69791 [0.62772, 0.7681] : 0.0531
Incremental AUROC (full-covars): 0.01676
PGS R2 (no covariates): 0.01004
PGS AUROC (no covariates): 0.5859 [0.50622, 0.66558]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008428 PGS001140
(GBE_HC1190)
PSS004179|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE seborrhoeic keratosis AUROC: 0.74674 [0.66312, 0.83035] : 0.10541
Incremental AUROC (full-covars): -0.00457
PGS R2 (no covariates): 0.01744
PGS AUROC (no covariates): 0.62007 [0.51848, 0.72165]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008429 PGS001140
(GBE_HC1190)
PSS004180|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE seborrhoeic keratosis AUROC: 0.63238 [0.61781, 0.64695] : 0.03162
Incremental AUROC (full-covars): 0.01328
PGS R2 (no covariates): 0.00595
PGS AUROC (no covariates): 0.55636 [0.54088, 0.57185]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008430 PGS001140
(GBE_HC1190)
PSS004181|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE seborrhoeic keratosis AUROC: 0.65125 [0.6056, 0.6969] Incremental AUROC (full-covars): 0.00972
: 0.03155
PGS R2 (no covariates): 0.00354
PGS AUROC (no covariates): 0.54802 [0.49607, 0.59996]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008431 PGS001140
(GBE_HC1190)
PSS004182|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE seborrhoeic keratosis AUROC: 0.62735 [0.61905, 0.63565] : 0.03214
Incremental AUROC (full-covars): 0.01502
PGS R2 (no covariates): 0.00744
PGS AUROC (no covariates): 0.56248 [0.55356, 0.57141]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008790 PGS001257
(GBE_INI1737)
PSS004876|
African Ancestry|
5,650 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Childhood sunburn : 9e-05 [-0.00037, 0.00054]
Incremental R2 (full-covars): -0.00203
PGS R2 (no covariates): 0.0 [-0.00007, 0.00008]
age, sex, UKB array type, Genotype PCs
PPM008791 PGS001257
(GBE_INI1737)
PSS004877|
East Asian Ancestry|
1,297 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Childhood sunburn : 0.01343 [0.0026, 0.02427]
Incremental R2 (full-covars): 0.00126
PGS R2 (no covariates): 0.00125 [-0.0021, 0.0046]
age, sex, UKB array type, Genotype PCs
PPM008792 PGS001257
(GBE_INI1737)
PSS004878|
European Ancestry|
19,358 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Childhood sunburn : 0.03588 [0.03135, 0.04042]
Incremental R2 (full-covars): 0.01262
PGS R2 (no covariates): 0.01397 [0.01107, 0.01686]
age, sex, UKB array type, Genotype PCs
PPM008793 PGS001257
(GBE_INI1737)
PSS004879|
South Asian Ancestry|
6,219 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Childhood sunburn : 0.00339 [0.00082, 0.00595]
Incremental R2 (full-covars): -0.00105
PGS R2 (no covariates): 0.00105 [-0.00038, 0.00249]
age, sex, UKB array type, Genotype PCs
PPM008794 PGS001257
(GBE_INI1737)
PSS004880|
European Ancestry|
50,754 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Childhood sunburn : 0.00954 [0.00808, 0.011]
Incremental R2 (full-covars): 0.00533
PGS R2 (no covariates): 0.00558 [0.00446, 0.0067]
age, sex, UKB array type, Genotype PCs
PPM009053 PGS001312
(GBE_HC38)
PSS004471|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriasis AUROC: 0.73107 [0.60624, 0.85591] : 0.06593
Incremental AUROC (full-covars): 0.0282
PGS R2 (no covariates): 0.01927
PGS AUROC (no covariates): 0.62557 [0.48848, 0.76266]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009054 PGS001312
(GBE_HC38)
PSS004472|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriasis AUROC: 0.88867 [0.80531, 0.97202] : 0.24575
Incremental AUROC (full-covars): 0.01187
PGS R2 (no covariates): 0.00399
PGS AUROC (no covariates): 0.57774 [0.40533, 0.75016]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009055 PGS001312
(GBE_HC38)
PSS004473|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriasis AUROC: 0.68424 [0.65757, 0.71091] : 0.05057
Incremental AUROC (full-covars): 0.0981
PGS R2 (no covariates): 0.04137
PGS AUROC (no covariates): 0.66409 [0.63596, 0.69222]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009056 PGS001312
(GBE_HC38)
PSS004474|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriasis AUROC: 0.6849 [0.63397, 0.73584] : 0.0448
Incremental AUROC (full-covars): 0.052
PGS R2 (no covariates): 0.02087
PGS AUROC (no covariates): 0.64825 [0.59861, 0.6979]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009057 PGS001312
(GBE_HC38)
PSS004475|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriasis AUROC: 0.69754 [0.68165, 0.71343] : 0.05574
Incremental AUROC (full-covars): 0.14505
PGS R2 (no covariates): 0.05226
PGS AUROC (no covariates): 0.69158 [0.6754, 0.70775]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009058 PGS001313
(GBE_HC1159)
PSS004158|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE psoriasis AUROC: 0.69906 [0.60273, 0.7954] : 0.04185
Incremental AUROC (full-covars): 0.01899
PGS R2 (no covariates): 0.00732
PGS AUROC (no covariates): 0.62223 [0.54291, 0.70154]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009059 PGS001313
(GBE_HC1159)
PSS004159|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE psoriasis AUROC: 0.72306 [0.61623, 0.82989] : 0.09162
Incremental AUROC (full-covars): 0.00222
PGS R2 (no covariates): 0.00378
PGS AUROC (no covariates): 0.48492 [0.37014, 0.5997]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009060 PGS001313
(GBE_HC1159)
PSS004160|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE psoriasis AUROC: 0.66545 [0.64532, 0.68558] : 0.04468
Incremental AUROC (full-covars): 0.07449
PGS R2 (no covariates): 0.0337
PGS AUROC (no covariates): 0.64565 [0.62471, 0.66658]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009061 PGS001313
(GBE_HC1159)
PSS004161|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE psoriasis AUROC: 0.63418 [0.59417, 0.67419] : 0.0236
Incremental AUROC (full-covars): 0.05154
PGS R2 (no covariates): 0.0123
PGS AUROC (no covariates): 0.60455 [0.56482, 0.64428]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009062 PGS001313
(GBE_HC1159)
PSS004162|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE psoriasis AUROC: 0.67543 [0.66285, 0.68801] : 0.05117
Incremental AUROC (full-covars): 0.13853
PGS R2 (no covariates): 0.04966
PGS AUROC (no covariates): 0.6729 [0.66027, 0.68553]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005215 PGS001536
(GBE_HC1188)
PSS004173|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE vitiligo AUROC: 0.63509 [0.52563, 0.74454] : 0.01654
Incremental AUROC (full-covars): -0.00281
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.51169 [0.39527, 0.62811]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005216 PGS001536
(GBE_HC1188)
PSS004174|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE vitiligo AUROC: 0.82774 [0.75298, 0.90249] : 0.08055
Incremental AUROC (full-covars): 0.01924
PGS R2 (no covariates): 0.00431
PGS AUROC (no covariates): 0.57823 [0.37976, 0.7767]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005217 PGS001536
(GBE_HC1188)
PSS004175|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE vitiligo AUROC: 0.6991 [0.61917, 0.77902] : 0.03993
Incremental AUROC (full-covars): 0.01341
PGS R2 (no covariates): 0.00254
PGS AUROC (no covariates): 0.55625 [0.47549, 0.63701]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005218 PGS001536
(GBE_HC1188)
PSS004176|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE vitiligo AUROC: 0.64566 [0.58746, 0.70386] : 0.02575
Incremental AUROC (full-covars): 0.0309
PGS R2 (no covariates): 0.01048
PGS AUROC (no covariates): 0.60302 [0.5391, 0.66694]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM005219 PGS001536
(GBE_HC1188)
PSS004177|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE vitiligo AUROC: 0.63449 [0.58754, 0.68144] : 0.01686
Incremental AUROC (full-covars): 0.08163
PGS R2 (no covariates): 0.01621
PGS AUROC (no covariates): 0.64193 [0.59907, 0.68478]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009229 PGS001773
(PRS_atopicDermatitis)
PSS007661|
Multi-ancestry (including European)|
676 individuals
PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
Reported Trait: Moderate-to-severe aotpic dermatitis AUROC: 0.93 : 0.49 Age, sex, father's ethnicity, mother ethnicity Nagelkerke's R^2, only unrelated individuals were considered in the analyses
PPM009230 PGS001773
(PRS_atopicDermatitis)
PSS007661|
Multi-ancestry (including European)|
676 individuals
PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
Reported Trait: Food allergy AUROC: 0.75 Age, sex, father's ethnicity, mother ethnicity Only unrelated individuals were considered in the analyses
PPM009231 PGS001773
(PRS_atopicDermatitis)
PSS007661|
Multi-ancestry (including European)|
676 individuals
PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
Reported Trait: Allergic asthma AUROC: 0.75 Age, sex, father's ethnicity, mother ethnicity Only unrelated individuals were considered in the analyses
PPM009232 PGS001773
(PRS_atopicDermatitis)
PSS007661|
Multi-ancestry (including European)|
676 individuals
PGP000253 |
Simard M et al. J Allergy Clin Immunol (2020)
Reported Trait: Allergic rhinitis AUROC: 0.77 Age, sex, father's ethnicity, mother ethnicity Only unrelated individuals were considered in the analyses
PPM009334 PGS001803
(portability-PLR_172)
PSS008155|
South Asian Ancestry|
6,328 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): -0.0135 [-0.0382, 0.0112] sex, age, birth date, deprivation index, 16 PCs
PPM009335 PGS001803
(portability-PLR_172)
PSS007943|
East Asian Ancestry|
1,810 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.0054 [-0.041, 0.0517] sex, age, birth date, deprivation index, 16 PCs
PPM009336 PGS001803
(portability-PLR_172)
PSS007725|
African Ancestry|
2,483 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): -0.0065 [-0.046, 0.033] sex, age, birth date, deprivation index, 16 PCs
PPM009330 PGS001803
(portability-PLR_172)
PSS009273|
European Ancestry|
19,990 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.1136 [0.0999, 0.1272] sex, age, birth date, deprivation index, 16 PCs
PPM009331 PGS001803
(portability-PLR_172)
PSS009047|
European Ancestry|
4,134 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.0962 [0.0659, 0.1264] sex, age, birth date, deprivation index, 16 PCs
PPM009332 PGS001803
(portability-PLR_172)
PSS008601|
European Ancestry|
6,656 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.0762 [0.0522, 0.1001] sex, age, birth date, deprivation index, 16 PCs
PPM009333 PGS001803
(portability-PLR_172)
PSS008379|
Greater Middle Eastern Ancestry|
1,200 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.0694 [0.0123, 0.1259] sex, age, birth date, deprivation index, 16 PCs
PPM009337 PGS001803
(portability-PLR_172)
PSS008827|
African Ancestry|
3,924 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.0165 [-0.0149, 0.0479] sex, age, birth date, deprivation index, 16 PCs
PPM009841 PGS001869
(portability-PLR_681)
PSS009345|
European Ancestry|
19,807 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): 0.0142 sex, age, birth date, deprivation index, 16 PCs
PPM009842 PGS001869
(portability-PLR_681)
PSS009119|
European Ancestry|
4,093 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): -0.0247 [-0.0554, 0.006] sex, age, birth date, deprivation index, 16 PCs
PPM009843 PGS001869
(portability-PLR_681)
PSS008673|
European Ancestry|
6,586 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): -0.004 [-0.0282, 0.0201] sex, age, birth date, deprivation index, 16 PCs
PPM009844 PGS001869
(portability-PLR_681)
PSS008447|
Greater Middle Eastern Ancestry|
1,189 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): 0.0014 [-0.0559, 0.0587] sex, age, birth date, deprivation index, 16 PCs
PPM009845 PGS001869
(portability-PLR_681)
PSS008227|
South Asian Ancestry|
6,213 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): 0.0057 [-0.0192, 0.0306] sex, age, birth date, deprivation index, 16 PCs
PPM009846 PGS001869
(portability-PLR_681)
PSS008008|
East Asian Ancestry|
1,803 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): -0.0207 [-0.0671, 0.0257] sex, age, birth date, deprivation index, 16 PCs
PPM009847 PGS001869
(portability-PLR_681)
PSS007792|
African Ancestry|
2,440 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): -0.0078 [-0.0476, 0.0321] sex, age, birth date, deprivation index, 16 PCs
PPM009848 PGS001869
(portability-PLR_681)
PSS008896|
African Ancestry|
3,853 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): -0.0033 [-0.0349, 0.0284] sex, age, birth date, deprivation index, 16 PCs
PPM009857 PGS001871
(portability-PLR_696.4)
PSS009347|
European Ancestry|
19,615 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0636 [0.0497, 0.0775] sex, age, birth date, deprivation index, 16 PCs
PPM009858 PGS001871
(portability-PLR_696.4)
PSS009121|
European Ancestry|
4,059 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.107 [0.0764, 0.1374] sex, age, birth date, deprivation index, 16 PCs
PPM009859 PGS001871
(portability-PLR_696.4)
PSS008675|
European Ancestry|
6,554 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0404 [0.0162, 0.0646] sex, age, birth date, deprivation index, 16 PCs
PPM009860 PGS001871
(portability-PLR_696.4)
PSS008449|
Greater Middle Eastern Ancestry|
1,183 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0463 [-0.0112, 0.1035] sex, age, birth date, deprivation index, 16 PCs
PPM009861 PGS001871
(portability-PLR_696.4)
PSS008229|
South Asian Ancestry|
6,161 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0327 [0.0077, 0.0577] sex, age, birth date, deprivation index, 16 PCs
PPM009862 PGS001871
(portability-PLR_696.4)
PSS008010|
East Asian Ancestry|
1,784 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0079 [-0.0388, 0.0545] sex, age, birth date, deprivation index, 16 PCs
PPM009863 PGS001871
(portability-PLR_696.4)
PSS007794|
African Ancestry|
2,398 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0357 [-0.0045, 0.0757] sex, age, birth date, deprivation index, 16 PCs
PPM009864 PGS001871
(portability-PLR_696.4)
PSS008898|
African Ancestry|
3,834 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): -0.0065 [-0.0382, 0.0252] sex, age, birth date, deprivation index, 16 PCs
PPM009865 PGS001872
(portability-PLR_697)
PSS009348|
European Ancestry|
19,670 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0199 [0.0059, 0.0338] sex, age, birth date, deprivation index, 16 PCs
PPM009866 PGS001872
(portability-PLR_697)
PSS009122|
European Ancestry|
4,059 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0123 [-0.0186, 0.0431] sex, age, birth date, deprivation index, 16 PCs
PPM009867 PGS001872
(portability-PLR_697)
PSS008676|
European Ancestry|
6,565 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0166 [-0.0076, 0.0408] sex, age, birth date, deprivation index, 16 PCs
PPM009868 PGS001872
(portability-PLR_697)
PSS008450|
Greater Middle Eastern Ancestry|
1,186 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0554 [-0.002, 0.1124] sex, age, birth date, deprivation index, 16 PCs
PPM009869 PGS001872
(portability-PLR_697)
PSS008230|
South Asian Ancestry|
6,194 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.018 [-0.0069, 0.0429] sex, age, birth date, deprivation index, 16 PCs
PPM009871 PGS001872
(portability-PLR_697)
PSS008899|
African Ancestry|
3,882 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0332 [0.0017, 0.0647] sex, age, birth date, deprivation index, 16 PCs
PPM009870 PGS001872
(portability-PLR_697)
PSS007795|
African Ancestry|
2,441 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0157 [-0.0242, 0.0555] sex, age, birth date, deprivation index, 16 PCs
PPM009880 PGS001874
(portability-PLR_706.2)
PSS009351|
European Ancestry|
19,952 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0461 [0.0323, 0.06] sex, age, birth date, deprivation index, 16 PCs
PPM009881 PGS001874
(portability-PLR_706.2)
PSS009125|
European Ancestry|
4,124 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0709 [0.0404, 0.1013] sex, age, birth date, deprivation index, 16 PCs
PPM009882 PGS001874
(portability-PLR_706.2)
PSS008679|
European Ancestry|
6,646 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0466 [0.0225, 0.0706] sex, age, birth date, deprivation index, 16 PCs
PPM009883 PGS001874
(portability-PLR_706.2)
PSS008453|
Greater Middle Eastern Ancestry|
1,194 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0522 [-0.005, 0.1091] sex, age, birth date, deprivation index, 16 PCs
PPM009884 PGS001874
(portability-PLR_706.2)
PSS008233|
South Asian Ancestry|
6,311 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.049 [0.0243, 0.0736] sex, age, birth date, deprivation index, 16 PCs
PPM009885 PGS001874
(portability-PLR_706.2)
PSS008013|
East Asian Ancestry|
1,807 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): -0.0163 [-0.0627, 0.0301] sex, age, birth date, deprivation index, 16 PCs
PPM009886 PGS001874
(portability-PLR_706.2)
PSS007798|
African Ancestry|
2,471 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): -0.0263 [-0.0659, 0.0133] sex, age, birth date, deprivation index, 16 PCs
PPM009887 PGS001874
(portability-PLR_706.2)
PSS008902|
African Ancestry|
3,913 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): -0.01 [-0.0414, 0.0214] sex, age, birth date, deprivation index, 16 PCs
PPM010986 PGS002014
(portability-ldpred2_172)
PSS009273|
European Ancestry|
19,990 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.1242 [0.1105, 0.1378] sex, age, birth date, deprivation index, 16 PCs
PPM010990 PGS002014
(portability-ldpred2_172)
PSS008155|
South Asian Ancestry|
6,328 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): -0.0147 [-0.0394, 0.01] sex, age, birth date, deprivation index, 16 PCs
PPM010991 PGS002014
(portability-ldpred2_172)
PSS007943|
East Asian Ancestry|
1,810 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): -0.0041 [-0.0504, 0.0423] sex, age, birth date, deprivation index, 16 PCs
PPM010992 PGS002014
(portability-ldpred2_172)
PSS007725|
African Ancestry|
2,483 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): -0.0062 [-0.0457, 0.0333] sex, age, birth date, deprivation index, 16 PCs
PPM010993 PGS002014
(portability-ldpred2_172)
PSS008827|
African Ancestry|
3,924 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.0146 [-0.0168, 0.0459] sex, age, birth date, deprivation index, 16 PCs
PPM010987 PGS002014
(portability-ldpred2_172)
PSS009047|
European Ancestry|
4,134 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.0876 [0.0572, 0.1178] sex, age, birth date, deprivation index, 16 PCs
PPM010988 PGS002014
(portability-ldpred2_172)
PSS008601|
European Ancestry|
6,656 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.076 [0.0521, 0.0999] sex, age, birth date, deprivation index, 16 PCs
PPM010989 PGS002014
(portability-ldpred2_172)
PSS008379|
Greater Middle Eastern Ancestry|
1,200 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Skin cancer Partial Correlation (partial-r): 0.0717 [0.0147, 0.1282] sex, age, birth date, deprivation index, 16 PCs
PPM011509 PGS002081
(portability-ldpred2_681)
PSS009345|
European Ancestry|
19,807 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): 0.0247 [0.0108, 0.0386] sex, age, birth date, deprivation index, 16 PCs
PPM011510 PGS002081
(portability-ldpred2_681)
PSS009119|
European Ancestry|
4,093 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): 0.0189 [-0.0118, 0.0496] sex, age, birth date, deprivation index, 16 PCs
PPM011511 PGS002081
(portability-ldpred2_681)
PSS008673|
European Ancestry|
6,586 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): 0.009 [-0.0152, 0.0332] sex, age, birth date, deprivation index, 16 PCs
PPM011512 PGS002081
(portability-ldpred2_681)
PSS008447|
Greater Middle Eastern Ancestry|
1,189 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): 0.021 [-0.0364, 0.0782] sex, age, birth date, deprivation index, 16 PCs
PPM011513 PGS002081
(portability-ldpred2_681)
PSS008227|
South Asian Ancestry|
6,213 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): 0.0082 [-0.0167, 0.0331] sex, age, birth date, deprivation index, 16 PCs
PPM011514 PGS002081
(portability-ldpred2_681)
PSS008008|
East Asian Ancestry|
1,803 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): -0.0251 [-0.0715, 0.0213] sex, age, birth date, deprivation index, 16 PCs
PPM011516 PGS002081
(portability-ldpred2_681)
PSS008896|
African Ancestry|
3,853 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): -0.0005 [-0.0321, 0.0312] sex, age, birth date, deprivation index, 16 PCs
PPM011515 PGS002081
(portability-ldpred2_681)
PSS007792|
African Ancestry|
2,440 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Superficial cellulitis and abscess Partial Correlation (partial-r): -0.0119 [-0.0518, 0.0279] sex, age, birth date, deprivation index, 16 PCs
PPM011525 PGS002083
(portability-ldpred2_696.4)
PSS009347|
European Ancestry|
19,615 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0632 [0.0493, 0.0771] sex, age, birth date, deprivation index, 16 PCs
PPM011526 PGS002083
(portability-ldpred2_696.4)
PSS009121|
European Ancestry|
4,059 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.1153 [0.0847, 0.1456] sex, age, birth date, deprivation index, 16 PCs
PPM011527 PGS002083
(portability-ldpred2_696.4)
PSS008675|
European Ancestry|
6,554 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.041 [0.0168, 0.0652] sex, age, birth date, deprivation index, 16 PCs
PPM011529 PGS002083
(portability-ldpred2_696.4)
PSS008229|
South Asian Ancestry|
6,161 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.03 [0.005, 0.055] sex, age, birth date, deprivation index, 16 PCs
PPM011530 PGS002083
(portability-ldpred2_696.4)
PSS008010|
East Asian Ancestry|
1,784 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0119 [-0.0348, 0.0585] sex, age, birth date, deprivation index, 16 PCs
PPM011531 PGS002083
(portability-ldpred2_696.4)
PSS007794|
African Ancestry|
2,398 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0375 [-0.0027, 0.0776] sex, age, birth date, deprivation index, 16 PCs
PPM011532 PGS002083
(portability-ldpred2_696.4)
PSS008898|
African Ancestry|
3,834 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): -0.0166 [-0.0483, 0.0152] sex, age, birth date, deprivation index, 16 PCs
PPM011528 PGS002083
(portability-ldpred2_696.4)
PSS008449|
Greater Middle Eastern Ancestry|
1,183 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Psoriasis Partial Correlation (partial-r): 0.0458 [-0.0117, 0.1031] sex, age, birth date, deprivation index, 16 PCs
PPM011533 PGS002084
(portability-ldpred2_697)
PSS009348|
European Ancestry|
19,670 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0184 [0.0044, 0.0324] sex, age, birth date, deprivation index, 16 PCs
PPM011534 PGS002084
(portability-ldpred2_697)
PSS009122|
European Ancestry|
4,059 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0038 [-0.0271, 0.0346] sex, age, birth date, deprivation index, 16 PCs
PPM011535 PGS002084
(portability-ldpred2_697)
PSS008676|
European Ancestry|
6,565 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0103 [-0.0139, 0.0345] sex, age, birth date, deprivation index, 16 PCs
PPM011536 PGS002084
(portability-ldpred2_697)
PSS008450|
Greater Middle Eastern Ancestry|
1,186 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0603 [0.0029, 0.1173] sex, age, birth date, deprivation index, 16 PCs
PPM011537 PGS002084
(portability-ldpred2_697)
PSS008230|
South Asian Ancestry|
6,194 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0182 [-0.0067, 0.0432] sex, age, birth date, deprivation index, 16 PCs
PPM011538 PGS002084
(portability-ldpred2_697)
PSS007795|
African Ancestry|
2,441 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0131 [-0.0268, 0.0529] sex, age, birth date, deprivation index, 16 PCs
PPM011539 PGS002084
(portability-ldpred2_697)
PSS008899|
African Ancestry|
3,882 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sarcoidosis Partial Correlation (partial-r): 0.0187 [-0.0128, 0.0502] sex, age, birth date, deprivation index, 16 PCs
PPM011540 PGS002085
(portability-ldpred2_702.2)
PSS009349|
European Ancestry|
19,837 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Seborrheic keratosis Partial Correlation (partial-r): 0.0237 [0.0098, 0.0376] sex, age, birth date, deprivation index, 16 PCs
PPM011541 PGS002085
(portability-ldpred2_702.2)
PSS009123|
European Ancestry|
4,111 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Seborrheic keratosis Partial Correlation (partial-r): 0.03 sex, age, birth date, deprivation index, 16 PCs
PPM011542 PGS002085
(portability-ldpred2_702.2)
PSS008677|
European Ancestry|
6,626 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Seborrheic keratosis Partial Correlation (partial-r): 0.0128 [-0.0113, 0.0369] sex, age, birth date, deprivation index, 16 PCs
PPM011543 PGS002085
(portability-ldpred2_702.2)
PSS008451|
Greater Middle Eastern Ancestry|
1,197 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Seborrheic keratosis Partial Correlation (partial-r): 0.0512 [-0.006, 0.108] sex, age, birth date, deprivation index, 16 PCs
PPM011544 PGS002085
(portability-ldpred2_702.2)
PSS008231|
South Asian Ancestry|
6,321 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Seborrheic keratosis Partial Correlation (partial-r): -0.0097 [-0.0344, 0.015] sex, age, birth date, deprivation index, 16 PCs
PPM011545 PGS002085
(portability-ldpred2_702.2)
PSS008011|
East Asian Ancestry|
1,807 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Seborrheic keratosis Partial Correlation (partial-r): -0.0149 [-0.0612, 0.0315] sex, age, birth date, deprivation index, 16 PCs
PPM011546 PGS002085
(portability-ldpred2_702.2)
PSS007796|
African Ancestry|
2,483 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Seborrheic keratosis Partial Correlation (partial-r): 0.0158 [-0.0237, 0.0553] sex, age, birth date, deprivation index, 16 PCs
PPM011547 PGS002085
(portability-ldpred2_702.2)
PSS008900|
African Ancestry|
3,922 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Seborrheic keratosis Partial Correlation (partial-r): -0.0283 [-0.0596, 0.0031] sex, age, birth date, deprivation index, 16 PCs
PPM011556 PGS002087
(portability-ldpred2_706.2)
PSS009351|
European Ancestry|
19,952 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0513 [0.0374, 0.0651] sex, age, birth date, deprivation index, 16 PCs
PPM011557 PGS002087
(portability-ldpred2_706.2)
PSS009125|
European Ancestry|
4,124 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0734 [0.0429, 0.1037] sex, age, birth date, deprivation index, 16 PCs
PPM011558 PGS002087
(portability-ldpred2_706.2)
PSS008679|
European Ancestry|
6,646 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0454 [0.0214, 0.0694] sex, age, birth date, deprivation index, 16 PCs
PPM011559 PGS002087
(portability-ldpred2_706.2)
PSS008453|
Greater Middle Eastern Ancestry|
1,194 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0444 [-0.0128, 0.1014] sex, age, birth date, deprivation index, 16 PCs
PPM011560 PGS002087
(portability-ldpred2_706.2)
PSS008233|
South Asian Ancestry|
6,311 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0351 [0.0103, 0.0597] sex, age, birth date, deprivation index, 16 PCs
PPM011561 PGS002087
(portability-ldpred2_706.2)
PSS008013|
East Asian Ancestry|
1,807 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): -0.0299 [-0.0762, 0.0165] sex, age, birth date, deprivation index, 16 PCs
PPM011562 PGS002087
(portability-ldpred2_706.2)
PSS007798|
African Ancestry|
2,471 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): -0.0274 [-0.067, 0.0122] sex, age, birth date, deprivation index, 16 PCs
PPM011563 PGS002087
(portability-ldpred2_706.2)
PSS008902|
African Ancestry|
3,913 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Sebaceous cyst Partial Correlation (partial-r): 0.0023 [-0.0291, 0.0338] sex, age, birth date, deprivation index, 16 PCs
PPM013020 PGS002293
(PRS62_psoriasis)
PSS009651|
European Ancestry|
345,672 individuals
PGP000323 |
Shen M et al. J Am Acad Dermatol (2022)
Reported Trait: Incident psoriasis HR: 4.625 [2.92, 7.348] Odds Ratio (OR, poor lifestyle and high genetic risk): 4.625 [2.92, 7.348]
Population-attributable fraction of genetic risk: 0.13 [0.032, 0.218]
Age, sex, education, Townsend Index, and region, relatedness, number of alleles included in the polygenic risk score, and first 20 principal components of ancestry
PPM013085 PGS002320
(disease_DERMATOLOGY.BOLT-LMM)
PSS009723|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0005 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013134 PGS002320
(disease_DERMATOLOGY.BOLT-LMM)
PSS009724|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013183 PGS002320
(disease_DERMATOLOGY.BOLT-LMM)
PSS009725|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0032 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013232 PGS002320
(disease_DERMATOLOGY.BOLT-LMM)
PSS009726|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013109 PGS002344
(disease_PSORIASIS.BOLT-LMM)
PSS009819|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013158 PGS002344
(disease_PSORIASIS.BOLT-LMM)
PSS009820|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013207 PGS002344
(disease_PSORIASIS.BOLT-LMM)
PSS009821|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.007 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013256 PGS002344
(disease_PSORIASIS.BOLT-LMM)
PSS009822|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0035 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013373 PGS002392
(disease_DERMATOLOGY.P+T.0.0001)
PSS009723|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013422 PGS002392
(disease_DERMATOLOGY.P+T.0.0001)
PSS009724|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013471 PGS002392
(disease_DERMATOLOGY.P+T.0.0001)
PSS009725|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013520 PGS002392
(disease_DERMATOLOGY.P+T.0.0001)
PSS009726|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013397 PGS002416
(disease_PSORIASIS.P+T.0.0001)
PSS009819|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0005 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013446 PGS002416
(disease_PSORIASIS.P+T.0.0001)
PSS009820|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013495 PGS002416
(disease_PSORIASIS.P+T.0.0001)
PSS009821|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013544 PGS002416
(disease_PSORIASIS.P+T.0.0001)
PSS009822|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013569 PGS002441
(disease_DERMATOLOGY.P+T.0.001)
PSS009723|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013618 PGS002441
(disease_DERMATOLOGY.P+T.0.001)
PSS009724|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013667 PGS002441
(disease_DERMATOLOGY.P+T.0.001)
PSS009725|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013716 PGS002441
(disease_DERMATOLOGY.P+T.0.001)
PSS009726|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013593 PGS002465
(disease_PSORIASIS.P+T.0.001)
PSS009819|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0003 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013642 PGS002465
(disease_PSORIASIS.P+T.0.001)
PSS009820|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013691 PGS002465
(disease_PSORIASIS.P+T.0.001)
PSS009821|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013740 PGS002465
(disease_PSORIASIS.P+T.0.001)
PSS009822|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013765 PGS002490
(disease_DERMATOLOGY.P+T.0.01)
PSS009723|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013814 PGS002490
(disease_DERMATOLOGY.P+T.0.01)
PSS009724|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013863 PGS002490
(disease_DERMATOLOGY.P+T.0.01)
PSS009725|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013912 PGS002490
(disease_DERMATOLOGY.P+T.0.01)
PSS009726|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013789 PGS002514
(disease_PSORIASIS.P+T.0.01)
PSS009819|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0003 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013838 PGS002514
(disease_PSORIASIS.P+T.0.01)
PSS009820|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013887 PGS002514
(disease_PSORIASIS.P+T.0.01)
PSS009821|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013936 PGS002514
(disease_PSORIASIS.P+T.0.01)
PSS009822|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013961 PGS002539
(disease_DERMATOLOGY.P+T.1e-06)
PSS009723|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014010 PGS002539
(disease_DERMATOLOGY.P+T.1e-06)
PSS009724|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0037 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014059 PGS002539
(disease_DERMATOLOGY.P+T.1e-06)
PSS009725|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014108 PGS002539
(disease_DERMATOLOGY.P+T.1e-06)
PSS009726|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM013985 PGS002563
(disease_PSORIASIS.P+T.1e-06)
PSS009819|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0004 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014034 PGS002563
(disease_PSORIASIS.P+T.1e-06)
PSS009820|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014083 PGS002563
(disease_PSORIASIS.P+T.1e-06)
PSS009821|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014132 PGS002563
(disease_PSORIASIS.P+T.1e-06)
PSS009822|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014157 PGS002588
(disease_DERMATOLOGY.P+T.5e-08)
PSS009723|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014206 PGS002588
(disease_DERMATOLOGY.P+T.5e-08)
PSS009724|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0022 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014255 PGS002588
(disease_DERMATOLOGY.P+T.5e-08)
PSS009725|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014304 PGS002588
(disease_DERMATOLOGY.P+T.5e-08)
PSS009726|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014181 PGS002612
(disease_PSORIASIS.P+T.5e-08)
PSS009819|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0007 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014230 PGS002612
(disease_PSORIASIS.P+T.5e-08)
PSS009820|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014279 PGS002612
(disease_PSORIASIS.P+T.5e-08)
PSS009821|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014328 PGS002612
(disease_PSORIASIS.P+T.5e-08)
PSS009822|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014353 PGS002637
(disease_DERMATOLOGY.PolyFun-pred)
PSS009723|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0005 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs See disease_DERMATOLOGY.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014402 PGS002637
(disease_DERMATOLOGY.PolyFun-pred)
PSS009724|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0009 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs See disease_DERMATOLOGY.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014451 PGS002637
(disease_DERMATOLOGY.PolyFun-pred)
PSS009725|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0032 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs See disease_DERMATOLOGY.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014500 PGS002637
(disease_DERMATOLOGY.PolyFun-pred)
PSS009726|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0011 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs See disease_DERMATOLOGY.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014377 PGS002661
(disease_PSORIASIS.PolyFun-pred)
PSS009819|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014426 PGS002661
(disease_PSORIASIS.PolyFun-pred)
PSS009820|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014475 PGS002661
(disease_PSORIASIS.PolyFun-pred)
PSS009821|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.007 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014524 PGS002661
(disease_PSORIASIS.PolyFun-pred)
PSS009822|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0034 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs See disease_PSORIASIS.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights
PPM014549 PGS002686
(disease_DERMATOLOGY.SBayesR)
PSS009723|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0011 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014598 PGS002686
(disease_DERMATOLOGY.SBayesR)
PSS009724|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014647 PGS002686
(disease_DERMATOLOGY.SBayesR)
PSS009725|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0016 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014696 PGS002686
(disease_DERMATOLOGY.SBayesR)
PSS009726|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Dermatologic diseases Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014622 PGS002710
(disease_PSORIASIS.SBayesR)
PSS009820|
East Asian Ancestry|
922 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0002 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014671 PGS002710
(disease_PSORIASIS.SBayesR)
PSS009821|
European Ancestry|
43,505 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0014 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014720 PGS002710
(disease_PSORIASIS.SBayesR)
PSS009822|
South Asian Ancestry|
8,098 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.002 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs
PPM014573 PGS002710
(disease_PSORIASIS.SBayesR)
PSS009819|
African Ancestry|
6,503 individuals
PGP000332 |
Weissbrod O et al. Nat Genet (2022)
Reported Trait: Psoriasis Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age‚age*sex, assessment center, genotyping array, 10 PCs

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS004156
[
  • 850 cases
  • , 6,981 controls
]
South Asian UKB
PSS004157
[
  • 6,461 cases
  • , 60,964 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004158
[
  • 32 cases
  • , 6,465 controls
]
African unspecified UKB
PSS004159
[
  • 22 cases
  • , 1,682 controls
]
East Asian UKB
PSS004160
[
  • 723 cases
  • , 24,182 controls
]
European non-white British ancestry UKB
PSS004161
[
  • 186 cases
  • , 7,645 controls
]
South Asian UKB
PSS004162
[
  • 1,956 cases
  • , 65,469 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004168
[
  • 141 cases
  • , 6,356 controls
]
African unspecified UKB
PSS004169
[
  • 29 cases
  • , 1,675 controls
]
East Asian UKB
PSS004170
[
  • 668 cases
  • , 24,237 controls
]
European non-white British ancestry UKB
PSS004171
[
  • 180 cases
  • , 7,651 controls
]
South Asian UKB
PSS004172
[
  • 1,995 cases
  • , 65,430 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004173
[
  • 17 cases
  • , 6,480 controls
]
African unspecified UKB
PSS004174
[
  • 6 cases
  • , 1,698 controls
]
East Asian UKB
PSS004175
[
  • 45 cases
  • , 24,860 controls
]
European non-white British ancestry UKB
PSS004176
[
  • 71 cases
  • , 7,760 controls
]
South Asian UKB
PSS004177
[
  • 131 cases
  • , 67,294 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004178
[
  • 54 cases
  • , 6,443 controls
]
African unspecified UKB
PSS004179
[
  • 37 cases
  • , 1,667 controls
]
East Asian UKB
PSS004180
[
  • 1,295 cases
  • , 23,610 controls
]
European non-white British ancestry UKB
PSS004181
[
  • 113 cases
  • , 7,718 controls
]
South Asian UKB
PSS004182
[
  • 4,266 cases
  • , 63,159 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS008155 6,328 individuals South Asian India (South Asia) UKB
PSS008673 6,586 individuals European Italy (South Europe) UKB
PSS008675 6,554 individuals European Italy (South Europe) UKB
PSS008676 6,565 individuals European Italy (South Europe) UKB
PSS008677 6,626 individuals European Italy (South Europe) UKB
PSS008679 6,646 individuals European Italy (South Europe) UKB
PSS008227 6,213 individuals South Asian India (South Asia) UKB
PSS008229 6,161 individuals South Asian India (South Asia) UKB
PSS008230 6,194 individuals South Asian India (South Asia) UKB
PSS008231 6,321 individuals South Asian India (South Asia) UKB
PSS008233 6,311 individuals South Asian India (South Asia) UKB
PSS007725 2,483 individuals African American or Afro-Caribbean Carribean UKB
PSS009273 19,990 individuals European UK (+ Ireland) UKB
PSS000463 Unaffected family members from families with increased melaona risk. Recruited families were ranked as low-, medium- or high-risk using a risk index (T) that factored in the number of confirmed cases of melanoma versus number of unaffected family members, ages and year of birth
[
  • 1,292 cases
  • , 1,774 controls
]
,
46.28 % Male samples
European Australia BATS, QFMP
PSS000464 Unaffected family members from families with increased melaona risk. Recruited families were ranked as low-, medium- or high-risk using a risk index (T) that factored in the number of confirmed cases of melanoma versus number of unaffected family members, ages and year of birth
[
  • 111 cases
  • , 1,774 controls
]
,
46.37 % Male samples
European Australia BATS, QFMP
PSS000207 PheCode 172
[
  • 3,002 cases
  • , 17,466 controls
]
,
46.9 % Male samples
Mean = 54.2 years
Sd = 15.9 years
European MGI
PSS000209 Basal cell carcinoma: ICD9-173.01,173.11,173.21,173.31,173.41,173.51,173.61,173.71,173.81,173.91
[
  • 884 cases
  • , 19,584 controls
]
,
46.9 % Male samples
Mean = 54.2 years
Sd = 15.9 years
European MGI
PSS000211 PheCode 172
[
  • 13,624 cases
  • , 136,233 controls
]
,
45.9 % Male samples
Mean = 57.7 years
Sd = 8.1 years
European White British Subset UKB
PSS007792 2,440 individuals African American or Afro-Caribbean Carribean UKB
PSS007794 2,398 individuals African American or Afro-Caribbean Carribean UKB
PSS007795 2,441 individuals African American or Afro-Caribbean Carribean UKB
PSS007796 2,483 individuals African American or Afro-Caribbean Carribean UKB
PSS007798 2,471 individuals African American or Afro-Caribbean Carribean UKB
PSS008827 3,924 individuals African unspecified Nigeria (West Africa) UKB
PSS009345 19,807 individuals European UK (+ Ireland) UKB
PSS009347 19,615 individuals European UK (+ Ireland) UKB
PSS009348 19,670 individuals European UK (+ Ireland) UKB
PSS009349 19,837 individuals European UK (+ Ireland) UKB
PSS009351 19,952 individuals European UK (+ Ireland) UKB
PSS009651 Median = 10.88 years 345,672 individuals,
48.0 % Male samples
Mean = 56.53 years
Sd = 8.06 years
European UKB
PSS000489 The diagnosttic criteria for each disease was based on gold-standard clinical guidelines. 339 individuals European
(Spanish)
PRECISESADS
PSS004876 5,650 individuals African unspecified UKB
PSS004877 1,297 individuals East Asian UKB
PSS004878 19,358 individuals European non-white British ancestry UKB
PSS004879 6,219 individuals South Asian UKB
PSS004880 50,754 individuals European white British ancestry UKB Testing cohort (heldout set)
PSS004384
[
  • 157 cases
  • , 6,340 controls
]
African unspecified UKB
PSS004385
[
  • 66 cases
  • , 1,638 controls
]
East Asian UKB
PSS004386
[
  • 873 cases
  • , 24,032 controls
]
European non-white British ancestry UKB
PSS004387
[
  • 243 cases
  • , 7,588 controls
]
South Asian UKB
PSS004388
[
  • 2,514 cases
  • , 64,911 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS000871 Basal cell carcinoma cases were determined by a baseline survey containing 34 questions regarding personal history of skin cancer(including skin cancer type, age at diagnosis, body location, prescribed treatments and information regarding cancer recurrence)
[
  • 16,184 cases
  • , 72,740 controls
]
,
38.9 % Male samples
European 23andMe
PSS000544 PheCode:172.21; ICD9CM:173.01, 173.11, 173.21, 173.31, 173.41, 173.51, 173.61, 173.71, 173.81, 173.91; ICD10CM:C44.01, C44.111, C44.112, C44.119, C44.211, C44.212, C44.219, C44.310, C44.311, C44.319, C44.41, C44.510, C44.511, C44.519, C44.611, C44.612, C44.619, C44.711, C44.712, C44.719, C44.81, C44.91
[
  • 1,481 cases
  • , 9,841 controls
]
European MGI
PSS008379 1,200 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS000546 PheCode:172.2; ICD9CM:173.00, 173.01, 173.02, 173.09, 173.10, 173.11, 173.12, 173.19, 173.20, 173.21, 173.22, 173.29, 173.30, 173.31, 173.32, 173.39, 173.40, 173.41, 173.42, 173.49, 173.50, 173.51, 173.52, 173.59, 173.60, 173.61, 173.62, 173.69, 173.70, 173.71, 173.72, 173.79, 173.80, 173.81, 173.82, 173.89, 173.90, 173.91, 173.92, 173.99, 209.31, 209.32, 209.33, 209.34, 209.35, 209.36, V10.83; ICD10CM:C44.0, C44.00, C44.01, C44.02, C44.09, C44.1, C44.10, C44.101, C44.102, C44.109, C44.11, C44.111, C44.112, C44.119, C44.12, C44.121, C44.122, C44.129, C44.19, C44.191, C44.192, C44.199, C44.2, C44.20, C44.201, C44.202, C44.209, C44.21, C44.211, C44.212, C44.219, C44.22, C44.221, C44.222, C44.229, C44.29, C44.291, C44.292, C44.299, C44.30, C44.300, C44.301, C44.309, C44.31, C44.310, C44.311, C44.319, C44.320, C44.321, C44.329, C44.39, C44.390, C44.391, C44.399, C44.4, C44.40, C44.41, C44.42, C44.49, C44.500, C44.501, C44.509, C44.51, C44.510, C44.511, C44.519, C44.52, C44.520, C44.521, C44.529, C44.59, C44.590, C44.591, C44.599, C44.6, C44.60, C44.601, C44.602, C44.609, C44.61, C44.611, C44.612, C44.619, C44.62, C44.621, C44.622, C44.629, C44.69, C44.691, C44.692, C44.699, C44.7, C44.70, C44.701, C44.702, C44.709, C44.71, C44.711, C44.712, C44.719, C44.72, C44.721, C44.722, C44.729, C44.79, C44.791, C44.792, C44.799, C44.8, C44.80, C44.81, C44.82, C44.89, C44.9, C44.90, C44.91, C44.92, C44.99, C4A, C4A.0, C4A.1, C4A.10, C4A.11, C4A.12, C4A.2, C4A.20, C4A.21, C4A.22, C4A.3, C4A.30, C4A.31, C4A.39, C4A.4, C4A.5, C4A.51, C4A.52, C4A.59, C4A.6, C4A.60, C4A.61, C4A.62, C4A.7, C4A.70, C4A.71, C4A.72, C4A.8, C4A.9
[
  • 2,954 cases
  • , 12,944 controls
]
European MGI
PSS000547 PheCode:172.3; ICD9CM:232.0, 232.1, 232.2, 232.3, 232.4, 232.5, 232.6, 232.7, 232.8, 232.9; ICD10CM:D04, D04.0, D04.1, D04.10, D04.11, D04.12, D04.2, D04.20, D04.21, D04.22, D04.3, D04.30, D04.39, D04.4, D04.5, D04.6, D04.60, D04.61, D04.62, D04.7, D04.70, D04.71, D04.72, D04.8, D04.9
[
  • 585 cases
  • , 4,915 controls
]
European MGI
PSS000548 PheCode:172; ICD9CM:172.0, 172.1, 172.2, 172.3, 172.4, 172.5, 172.6, 172.7, 172.8, 172.9, 173.00, 173.01, 173.02, 173.09, 173.10, 173.11, 173.12, 173.19, 173.20, 173.21, 173.22, 173.29, 173.30, 173.31, 173.32, 173.39, 173.40, 173.41, 173.42, 173.49, 173.50, 173.51, 173.52, 173.59, 173.60, 173.61, 173.62, 173.69, 173.70, 173.71, 173.72, 173.79, 173.80, 173.81, 173.82, 173.89, 173.90, 173.91, 173.92, 173.99, 209.31, 209.32, 209.33, 209.34, 209.35, 209.36, 232.0, 232.1, 232.2, 232.3, 232.4, 232.5, 232.6, 232.7, 232.8, 232.9, V10.82, V10.83; ICD10CM:C43, C43.0, C43.1, C43.10, C43.11, C43.12, C43.2, C43.20, C43.21, C43.22, C43.3, C43.30, C43.31, C43.39, C43.4, C43.5, C43.51, C43.52, C43.59, C43.6, C43.60, C43.61, C43.62, C43.7, C43.70, C43.71, C43.72, C43.8, C43.9, C44.0, C44.00, C44.01, C44.02, C44.09, C44.1, C44.10, C44.101, C44.102, C44.109, C44.11, C44.111, C44.112, C44.119, C44.12, C44.121, C44.122, C44.129, C44.19, C44.191, C44.192, C44.199, C44.2, C44.20, C44.201, C44.202, C44.209, C44.21, C44.211, C44.212, C44.219, C44.22, C44.221, C44.222, C44.229, C44.29, C44.291, C44.292, C44.299, C44.30, C44.300, C44.301, C44.309, C44.31, C44.310, C44.311, C44.319, C44.320, C44.321, C44.329, C44.39, C44.390, C44.391, C44.399, C44.4, C44.40, C44.41, C44.42, C44.49, C44.500, C44.501, C44.509, C44.51, C44.510, C44.511, C44.519, C44.52, C44.520, C44.521, C44.529, C44.59, C44.590, C44.591, C44.599, C44.6, C44.60, C44.601, C44.602, C44.609, C44.61, C44.611, C44.612, C44.619, C44.62, C44.621, C44.622, C44.629, C44.69, C44.691, C44.692, C44.699, C44.7, C44.70, C44.701, C44.702, C44.709, C44.71, C44.711, C44.712, C44.719, C44.72, C44.721, C44.722, C44.729, C44.79, C44.791, C44.792, C44.799, C44.8, C44.80, C44.81, C44.82, C44.89, C44.9, C44.90, C44.91, C44.92, C44.99, C4A, C4A.0, C4A.1, C4A.10, C4A.11, C4A.12, C4A.2, C4A.20, C4A.21, C4A.22, C4A.3, C4A.30, C4A.31, C4A.39, C4A.4, C4A.5, C4A.51, C4A.52, C4A.59, C4A.6, C4A.60, C4A.61, C4A.62, C4A.7, C4A.70, C4A.71, C4A.72, C4A.8, C4A.9, D03, D03.0, D03.1, D03.10, D03.11, D03.12, D03.2, D03.20, D03.21, D03.22, D03.3, D03.30, D03.39, D03.4, D03.5, D03.51, D03.52, D03.59, D03.6, D03.60, D03.61, D03.62, D03.7, D03.70, D03.71, D03.72, D03.8, D03.9, D04, D04.0, D04.1, D04.10, D04.11, D04.12, D04.2, D04.20, D04.21, D04.22, D04.3, D04.30, D04.39, D04.4, D04.5, D04.6, D04.60, D04.61, D04.62, D04.7, D04.70, D04.71, D04.72, D04.8, D04.9
[
  • 3,557 cases
  • , 14,050 controls
]
European MGI
PSS008896 3,853 individuals African unspecified Nigeria (West Africa) UKB
PSS008898 3,834 individuals African unspecified Nigeria (West Africa) UKB
PSS008899 3,882 individuals African unspecified Nigeria (West Africa) UKB
PSS008900 3,922 individuals African unspecified Nigeria (West Africa) UKB
PSS008902 3,913 individuals African unspecified Nigeria (West Africa) UKB
PSS000568 PheCode:172.21; ICD9:173, 173.0, 173.1, 173.2, 173.3, 173.4, 173.5, 173.6, 173.7, 173.8, 173.9; ICD10:C44.0, C44.1, C44.2, C44.3, C44.4, C44.5, C44.6, C44.7, C44.8, C44.9
[
  • 5,450 cases
  • , 54,568 controls
]
European UKB
PSS000907 Cases are individuals with vitiligo. Diagnoses of vitiligo in multiplex-affected subjects and reportedly unaffected family members were verified by manual review of all available phenotype information for each subject.
[
  • 1,827 cases
  • , 2,181 controls
]
European NR
PSS004471
[
  • 19 cases
  • , 6,478 controls
]
African unspecified UKB
PSS004472
[
  • 10 cases
  • , 1,694 controls
]
East Asian UKB
PSS004473
[
  • 416 cases
  • , 24,489 controls
]
European non-white British ancestry UKB
PSS004474
[
  • 108 cases
  • , 7,723 controls
]
South Asian UKB
PSS004475
[
  • 1,146 cases
  • , 66,279 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS008447 1,189 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008449 1,183 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008450 1,186 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS007943 1,810 individuals East Asian China (East Asia) UKB
PSS008453 1,194 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008451 1,197 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS004516
[
  • 63 cases
  • , 6,434 controls
]
African unspecified UKB
PSS004517
[
  • 38 cases
  • , 1,666 controls
]
East Asian UKB
PSS004518
[
  • 690 cases
  • , 24,215 controls
]
European non-white British ancestry UKB
PSS004519
[
  • 148 cases
  • , 7,683 controls
]
South Asian UKB
PSS004520
[
  • 2,222 cases
  • , 65,203 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004521
[
  • 81 cases
  • , 6,416 controls
]
African unspecified UKB
PSS004522
[
  • 32 cases
  • , 1,672 controls
]
East Asian UKB
PSS004523
[
  • 781 cases
  • , 24,124 controls
]
European non-white British ancestry UKB
PSS004524
[
  • 307 cases
  • , 7,524 controls
]
South Asian UKB
PSS004525
[
  • 2,358 cases
  • , 65,067 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS009723 6,503 individuals African unspecified UKB
PSS009724 922 individuals East Asian UKB
PSS009725 43,505 individuals European Non-British European UKB
PSS009726 8,098 individuals South Asian UKB
PSS008008 1,803 individuals East Asian China (East Asia) UKB
PSS008010 1,784 individuals East Asian China (East Asia) UKB
PSS008011 1,807 individuals East Asian China (East Asia) UKB
PSS007621
[
  • 12 cases
  • , 6,485 controls
]
African unspecified UKB
PSS007622
[
  • 9 cases
  • , 1,695 controls
]
East Asian UKB
PSS007623
[
  • 1,649 cases
  • , 23,256 controls
]
European non-white British ancestry UKB
PSS007624
[
  • 20 cases
  • , 7,811 controls
]
South Asian UKB
PSS007625
[
  • 4,637 cases
  • , 62,788 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS008013 1,807 individuals East Asian China (East Asia) UKB
PSS009047 4,134 individuals European Poland (NE Europe) UKB
PSS007651
[
  • 11 cases
  • , 6,486 controls
]
African unspecified UKB
PSS007652
[
  • 6 cases
  • , 1,698 controls
]
East Asian UKB
PSS007653
[
  • 1,442 cases
  • , 23,463 controls
]
European non-white British ancestry UKB
PSS007654
[
  • 18 cases
  • , 7,813 controls
]
South Asian UKB
PSS007655
[
  • 4,141 cases
  • , 63,284 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007661 For the CHILD Cohort Study, atopic dermatitis (AD) was from physician diagnosis at the one year follow-up. AD severity was defined as mild if there is a single site or no more than 2 sites, minor symptoms (little itching/rubbing), minor crusting and papules, not excoriated or oozing, not needing frequent medical attention; was defined as moderate if symptoms are neither mild nor severe or; was defined as severe if there are multiple sites, with extensive crusting or papules or excoriations or oozing or lichenification, sleep loss, needing frequent medical attention, and is a major concern to parents. In the SLSJ Cohort, atopic dermatitis was self-reported and considered as positive if past or present occurrence was reported. For children, cross validation was done using questionnaires filled by their parents. Moreover, validation in medical records of these self-reported phenotypes were done for a subset of the SLSJ Cohort (n = 217), giving 89% concordance.
[
  • 61 cases
  • , 615 controls
]
,
42.0 % Male samples
Mean = 9.0 years
Range = [0.0, 87.0] years
European, South East Asian, East Asian, South Asian, African American or Afro-Caribbean, Native American, Greater Middle Eastern (Middle Eastern, North African or Persian), Hispanic or Latin American, Not reported CHILD, SLSJ Also used to evaluate the PRS_atopicDermatitis for other diseases of the atopic march: food allergy, allergic asthma and rhinitis. Only unrelated individuals were selected for analyses.
PSS000970 Median = 400.0 days 1,584 individuals European GNEHGI2020Q2
PSS009819 6,503 individuals African unspecified UKB
PSS009820 922 individuals East Asian UKB
PSS009821 43,505 individuals European Non-British European UKB
PSS009822 8,098 individuals South Asian UKB
PSS008601 6,656 individuals European Italy (South Europe) UKB
PSS009119 4,093 individuals European Poland (NE Europe) UKB
PSS009121 4,059 individuals European Poland (NE Europe) UKB
PSS009122 4,059 individuals European Poland (NE Europe) UKB
PSS009123 4,111 individuals European Poland (NE Europe) UKB
PSS000982 Cases were individuals with cutaneous melanoma. Of the 628 cases, 528 were prevalent melanoma, whilst 98 were incident melanoma cases. Endpoints used were primary invasive cutaneous melanoma and metastatic melanoma with unknown primary location occurring during the trial (incident). Metastatic recurrence was excluded. Incident melanomas were confirmed by expert panel using histopathology, imaging of metastasis or other clinical evidence. If a participant had two events during the trial, the time of the first event was used. Prevalent melanomas occurring pre-trial were self-reported by participants but not confirmed by review of medical records and assumed to be invasive. Age at diagnosis for self-reported melanomas was reported as either before or after 50 years. Median = 4.7 years
[
  • 626 cases
  • , 12,086 controls
]
,
45.0 % Male samples
Mean = 75.0 years
Sd = 4.23 years
European ASPREE
PSS009125 4,124 individuals European Poland (NE Europe) UKB
PSS004153
[
  • 343 cases
  • , 6,154 controls
]
African unspecified UKB
PSS004154
[
  • 143 cases
  • , 1,561 controls
]
East Asian UKB
PSS004155
[
  • 2,053 cases
  • , 22,852 controls
]
European non-white British ancestry UKB