| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS000017 (GPS_IBD) |
PGP000006 | Khera AV et al. Nat Genet (2018) |
Inflammatory bowel disease | inflammatory bowel disease | 6,907,112 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000017/ScoringFiles/PGS000017.txt.gz | |
| PGS000114 (GRS-JIA-20) |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Juvenile Idiopathic Arthritis | juvenile idiopathic arthritis | 26 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000114/ScoringFiles/PGS000114.txt.gz |
| PGS000194 (G-PROB_Rapos) |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Rheumatoid arthritis (CCP-negative) | ACPA-positive rheumatoid arthritis | 250 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000194/ScoringFiles/PGS000194.txt.gz |
| PGS000195 (G-PROB_Raneg) |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Rheumatoid arthritis (CCP-negative) | ACPA-negative rheumatoid arthritis | 250 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000195/ScoringFiles/PGS000195.txt.gz |
| PGS000196 (G-PROB_SLE) |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Systemic lupus erythematosus | systemic lupus erythematosus | 250 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000196/ScoringFiles/PGS000196.txt.gz |
| PGS000198 (G-PROB_PsA) |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Psoriatic arthritis | psoriatic arthritis | 250 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000198/ScoringFiles/PGS000198.txt.gz |
| PGS000324 (GRS-JIA-ERA-20) |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Enthesitis-related Juvenile Idiophatic Arthritis | enthesitis-related juvenile idiopathic arthritis | 138 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000324/ScoringFiles/PGS000324.txt.gz |
| PGS000325 (GRS-JIA-Oli-20) |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Oligoarthritis Juvenile Idiophatic Arthritis | oligoarticular juvenile idiopathic arthritis | 21 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000325/ScoringFiles/PGS000325.txt.gz |
| PGS000326 (GRS-JIA-RFN-20) |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Rheumatoid-factor-negative Polyarthritis (Juvenile Idiophatic Arthritis) | polyarticular juvenile idiopathic arthritis, rheumatoid factor negative | 12 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000326/ScoringFiles/PGS000326.txt.gz |
| PGS000328 (GRS_SLE) |
PGP000099 | Reid S et al. Ann Rheum Dis (2019) |
Systemic lupus erythematosus | systemic lupus erythematosus | 57 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000328/ScoringFiles/PGS000328.txt.gz |
| PGS000342 (wGRS_PsA) |
PGP000111 | Smith MP et al. J Psoriasis Psoriatic Arthritis (2020) |
Psoriatic arthritis | psoriatic arthritis | 11 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000342/ScoringFiles/PGS000342.txt.gz |
| PGS000343 (wGRS_PsA_HLA) |
PGP000111 | Smith MP et al. J Psoriasis Psoriatic Arthritis (2020) |
Psoriatic arthritis | psoriatic arthritis | 5 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000343/ScoringFiles/PGS000343.txt.gz |
| PGS000738 (CONFIRMED_PGS) |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Vitiligo | Vitiligo | 48 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000738/ScoringFiles/PGS000738.txt.gz |
| PGS000754 (PRS_SLE) |
PGP000160 | Wang YF et al. Nat Commun (2021) |
Systemic lupus erythematosus | systemic lupus erythematosus | 293,684 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000754/ScoringFiles/PGS000754.txt.gz |
| PGS000760 (VIT) |
PGP000164 | Khan Z et al. Nat Commun (2021) |
Vitiligo | Vitiligo | 42 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000760/ScoringFiles/PGS000760.txt.gz | |
| PGS000771 (GRS95_SLEmain) |
PGP000178 | Chen L et al. Hum Mol Genet (2020) |
Systemic lupus erythematosus | systemic lupus erythematosus | 95 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000771/ScoringFiles/PGS000771.txt.gz | |
| PGS000772 (GRS95_SLEgen) |
PGP000178 | Chen L et al. Hum Mol Genet (2020) |
Systemic lupus erythematosus | systemic lupus erythematosus | 95 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000772/ScoringFiles/PGS000772.txt.gz | |
| PGS000803 (wGRS41_SLE) |
PGP000192 | Kawai VK et al. Lupus (2021) |
Systemic lupus erythematosus | systemic lupus erythematosus | 41 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000803/ScoringFiles/PGS000803.txt.gz |
| PGS000809 (PRS127_MS) |
PGP000194 | Barnes CLK et al. Eur J Hum Genet (2021) |
Multiple sclerosis | multiple sclerosis | 127 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000809/ScoringFiles/PGS000809.txt.gz |
| PGS001042 (GBE_HC645) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Thyrotoxicosis [hyperthyroidism] (time-to-event) | Thyrotoxicosis | 226 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001042/ScoringFiles/PGS001042.txt.gz |
| PGS001043 (GBE_HC55) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Hyperthyroidism, thyrotoxicosis | hyperthyroidism, Thyrotoxicosis |
69 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001043/ScoringFiles/PGS001043.txt.gz |
| PGS001110 (GBE_HC1209) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reactive arthropathies (time-to-event) | reactive arthritis | 6 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001110/ScoringFiles/PGS001110.txt.gz |
| PGS001267 (GBE_HC422) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 10 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001267/ScoringFiles/PGS001267.txt.gz |
| PGS001268 (GBE_HC1242) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ankylosing spondylitis (time-to-event) | ankylosing spondylitis | 10 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001268/ScoringFiles/PGS001268.txt.gz |
| PGS001270 (GBE_HC151) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Multiple sclerosis | multiple sclerosis | 41 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001270/ScoringFiles/PGS001270.txt.gz |
| PGS001271 (GBE_HC810) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Multiple sclerosis (time-to-event) | multiple sclerosis | 36 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001271/ScoringFiles/PGS001271.txt.gz |
| PGS001287 (GBE_HC91) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Psoriatic arthropathy | psoriatic arthritis | 36 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001287/ScoringFiles/PGS001287.txt.gz |
| PGS001288 (GBE_HC95) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Inflammatory bowel disease | inflammatory bowel disease | 195 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001288/ScoringFiles/PGS001288.txt.gz |
| PGS001306 (GBE_HC201) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ulcerative colitis | ulcerative colitis | 179 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001306/ScoringFiles/PGS001306.txt.gz |
| PGS001307 (GBE_HC1102) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ulcerative colitis (time-to-event) | ulcerative colitis | 809 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001307/ScoringFiles/PGS001307.txt.gz |
| PGS001308 (GBE_HC321) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Sjogren's syndrome/sicca syndrome | Sjogren syndrome | 7 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001308/ScoringFiles/PGS001308.txt.gz |
| PGS001309 (GBE_HC1212) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Other rheumatoid arthritis (time-to-event) | rheumatoid arthritis | 323 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001309/ScoringFiles/PGS001309.txt.gz |
| PGS001310 (GBE_HC430) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 175 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001310/ScoringFiles/PGS001310.txt.gz |
| PGS001311 (GBE_HC1211) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Seropositive rheumatoid arthritis (time-to-event) | rheumatoid arthritis | 3 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001311/ScoringFiles/PGS001311.txt.gz |
| PGS001330 (GBE_HC1101) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Crohn's disease [regional enteritis] (time-to-event) | Crohn's disease | 220 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001330/ScoringFiles/PGS001330.txt.gz |
| PGS001331 (GBE_HC322) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Crohn's disease | Crohn's disease | 257 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001331/ScoringFiles/PGS001331.txt.gz |
| PGS001369 (GBE_HC1090) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Acute appendicitis (time-to-event) | appendicitis | 4 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001369/ScoringFiles/PGS001369.txt.gz |
| PGS001536 (GBE_HC1188) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Vitiligo (time-to-event) | Vitiligo | 77 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001536/ScoringFiles/PGS001536.txt.gz |
| PGS001785 (1kgeur_gbmi_leaveUKBBout_AcApp_pst_eff_a1_b0.5_phiauto) |
PGP000262 | Wang Y et al. Cell Genom (2023) |
Acute appendicitis | appendicitis | 911,334 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001785/ScoringFiles/PGS001785.txt.gz |
| PGS001815 (portability-PLR_242) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Thyrotoxicosis with or without goiter | Thyrotoxicosis | 280 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001815/ScoringFiles/PGS001815.txt.gz |
| PGS001831 (portability-PLR_335) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Multiple sclerosis | multiple sclerosis | 491 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001831/ScoringFiles/PGS001831.txt.gz |
| PGS001855 (portability-PLR_555.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ulcerative colitis | ulcerative colitis | 1,505 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001855/ScoringFiles/PGS001855.txt.gz |
| PGS001875 (portability-PLR_714.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 256 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001875/ScoringFiles/PGS001875.txt.gz |
| PGS001876 (portability-PLR_715.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 85 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001876/ScoringFiles/PGS001876.txt.gz |
| PGS002023 (portability-ldpred2_242) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Thyrotoxicosis with or without goiter | Thyrotoxicosis | 279,385 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002023/ScoringFiles/PGS002023.txt.gz |
| PGS002038 (portability-ldpred2_335) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Multiple sclerosis | multiple sclerosis | 129,077 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002038/ScoringFiles/PGS002038.txt.gz |
| PGS002066 (portability-ldpred2_555.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ulcerative colitis | ulcerative colitis | 566,637 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002066/ScoringFiles/PGS002066.txt.gz |
| PGS002088 (portability-ldpred2_714.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 95,083 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002088/ScoringFiles/PGS002088.txt.gz |
| PGS002089 (portability-ldpred2_715.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 22,026 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002089/ScoringFiles/PGS002089.txt.gz |
| PGS002260 (PRS_RA) |
PGP000286 | Honda S et al. Arthritis Rheumatol (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 43,784 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002260/ScoringFiles/PGS002260.txt.gz | |
| PGS002312 (disease_AID_ALL.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Autoimmune disease | autoimmune disease | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002312/ScoringFiles/PGS002312.txt.gz |
| PGS002359 (disease_AID_ALL.BOLT-LMM-BBJ) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Autoimmune disease | autoimmune disease | 920,927 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002359/ScoringFiles/PGS002359.txt.gz |
| PGS002384 (disease_AID_ALL.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Autoimmune disease | autoimmune disease | 2,563 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002384/ScoringFiles/PGS002384.txt.gz |
| PGS002433 (disease_AID_ALL.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Autoimmune disease | autoimmune disease | 13,075 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002433/ScoringFiles/PGS002433.txt.gz |
| PGS002482 (disease_AID_ALL.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Autoimmune disease | autoimmune disease | 88,404 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002482/ScoringFiles/PGS002482.txt.gz |
| PGS002531 (disease_AID_ALL.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Autoimmune disease | autoimmune disease | 382 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002531/ScoringFiles/PGS002531.txt.gz |
| PGS002580 (disease_AID_ALL.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Autoimmune disease | autoimmune disease | 206 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002580/ScoringFiles/PGS002580.txt.gz |
| PGS002629 (disease_AID_ALL.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Autoimmune disease | autoimmune disease | 159,127 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002629/ScoringFiles/PGS002629.txt.gz |
| PGS002678 (disease_AID_ALL.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Autoimmune disease | autoimmune disease | 923,726 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002678/ScoringFiles/PGS002678.txt.gz |
| PGS002726 (PGS_MS_Brain) |
PGP000334 | Shams H et al. Brain (2022) |
Multiple sclerosis | multiple sclerosis | 476,399 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002726/ScoringFiles/PGS002726.txt.gz |
| PGS002745 (metaPGS_RA) |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 2,575 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002745/ScoringFiles/PGS002745.txt.gz |
| PGS002769 (Rheumatoid_arthritis_prscs) |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Seropositive rheumatoid arthritis | rheumatoid arthritis | 1,083,565 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002769/ScoringFiles/PGS002769.txt.gz |
| PGS003420 (PRS100_PRScs) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 100 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003420/ScoringFiles/PGS003420.txt.gz |
| PGS003421 (PRS16_C+T) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 16 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003421/ScoringFiles/PGS003421.txt.gz |
| PGS003422 (PRS16_PRSice2) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 16 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003422/ScoringFiles/PGS003422.txt.gz |
| PGS003423 (PRS100_Lassosum) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 100 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003423/ScoringFiles/PGS003423.txt.gz |
| PGS003424 (PRS100_LDpred2) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 100 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003424/ScoringFiles/PGS003424.txt.gz |
| PGS003755 (wGRS_SLE) |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Systemic lupus erythematosus | systemic lupus erythematosus | 122 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003755/ScoringFiles/PGS003755.txt.gz |
| PGS003756 (wGRS_SLE_non-HLA) |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Systemic lupus erythematosus | systemic lupus erythematosus | 112 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003756/ScoringFiles/PGS003756.txt.gz |
| PGS003757 (wGRS_SLE_HLA) |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Systemic lupus erythematosus | systemic lupus erythematosus | 10 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003757/ScoringFiles/PGS003757.txt.gz |
| PGS003960 (GRS57_SLE) |
PGP000509 | Barnado A et al. Arthritis Rheumatol (2023) |
Systemic lupus erythematosus | systemic lupus erythematosus | 57 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003960/ScoringFiles/PGS003960.txt.gz |
| PGS003981 (dbslmm.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,103,311 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003981/ScoringFiles/PGS003981.txt.gz | |
| PGS003994 (dbslmm.auto.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 778,205 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003994/ScoringFiles/PGS003994.txt.gz | |
| PGS003997 (lassosum.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 8,406 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003997/ScoringFiles/PGS003997.txt.gz | |
| PGS004010 (lassosum.auto.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 27,045 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004010/ScoringFiles/PGS004010.txt.gz | |
| PGS004013 (lassosum.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 22,690 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004013/ScoringFiles/PGS004013.txt.gz | |
| PGS004021 (lassosum.CV.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 315,740 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004021/ScoringFiles/PGS004021.txt.gz | |
| PGS004023 (ldpred2.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,018,068 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004023/ScoringFiles/PGS004023.txt.gz | |
| PGS004038 (ldpred2.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,018,068 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004038/ScoringFiles/PGS004038.txt.gz | |
| PGS004049 (ldpred2.CV.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 373,627 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004049/ScoringFiles/PGS004049.txt.gz | |
| PGS004051 (megaprs.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 784,928 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004051/ScoringFiles/PGS004051.txt.gz | |
| PGS004064 (megaprs.auto.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 402,214 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004064/ScoringFiles/PGS004064.txt.gz | |
| PGS004067 (megaprs.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 784,928 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004067/ScoringFiles/PGS004067.txt.gz | |
| PGS004079 (megaprs.CV.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 402,214 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004079/ScoringFiles/PGS004079.txt.gz | |
| PGS004081 (prscs.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,073,268 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004081/ScoringFiles/PGS004081.txt.gz | |
| PGS004094 (prscs.auto.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 755,048 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004094/ScoringFiles/PGS004094.txt.gz | |
| PGS004097 (prscs.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,073,268 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004097/ScoringFiles/PGS004097.txt.gz | |
| PGS004103 (prscs.CV.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 755,048 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004103/ScoringFiles/PGS004103.txt.gz | |
| PGS004105 (pt_clump.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 139 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004105/ScoringFiles/PGS004105.txt.gz | |
| PGS004118 (pt_clump.auto.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 91 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004118/ScoringFiles/PGS004118.txt.gz | |
| PGS004121 (pt_clump_nested.CV.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 774 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004121/ScoringFiles/PGS004121.txt.gz | |
| PGS004133 (pt_clump_nested.CV.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 155 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004133/ScoringFiles/PGS004133.txt.gz | |
| PGS004135 (sbayesr.auto.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 912,746 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004135/ScoringFiles/PGS004135.txt.gz | |
| PGS004148 (sbayesr.auto.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 671,211 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004148/ScoringFiles/PGS004148.txt.gz | |
| PGS004151 (UKBB_EnsPGS.GCST004131.IBD) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Inflammatory bowel disease (IBD) | inflammatory bowel disease | 1,102,205 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004151/ScoringFiles/PGS004151.txt.gz | |
| PGS004163 (UKBB_EnsPGS.GCST90013534.RA) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 778,275 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004163/ScoringFiles/PGS004163.txt.gz | |
| PGS004253 (uc_ldpred2) |
PGP000545 | Middha P et al. Nat Commun (2024) |
Ulcerative colitis | ulcerative colitis | 744,575 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004253/ScoringFiles/PGS004253.txt.gz | |
| PGS004254 (cd_ldpred2) |
PGP000545 | Middha P et al. Nat Commun (2024) |
Crohn's disease | Crohn's disease | 744,682 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004254/ScoringFiles/PGS004254.txt.gz | |
| PGS004255 (GenoBoost_rheumatoid_arthritis_0) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 30 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004255/ScoringFiles/PGS004255.txt.gz |
| PGS004256 (GenoBoost_rheumatoid_arthritis_1) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004256/ScoringFiles/PGS004256.txt.gz |
| PGS004257 (GenoBoost_rheumatoid_arthritis_2) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004257/ScoringFiles/PGS004257.txt.gz |
| PGS004258 (GenoBoost_rheumatoid_arthritis_3) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004258/ScoringFiles/PGS004258.txt.gz |
| PGS004259 (GenoBoost_rheumatoid_arthritis_4) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004259/ScoringFiles/PGS004259.txt.gz |
| PGS004270 (GenoBoost_inflammatory_bowel_disease_0) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004270/ScoringFiles/PGS004270.txt.gz |
| PGS004271 (GenoBoost_inflammatory_bowel_disease_1) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004271/ScoringFiles/PGS004271.txt.gz |
| PGS004272 (GenoBoost_inflammatory_bowel_disease_2) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 100 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004272/ScoringFiles/PGS004272.txt.gz |
| PGS004273 (GenoBoost_inflammatory_bowel_disease_3) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 110 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004273/ScoringFiles/PGS004273.txt.gz |
| PGS004274 (GenoBoost_inflammatory_bowel_disease_4) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Inflammatory bowel disease | inflammatory bowel disease | 40 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004274/ScoringFiles/PGS004274.txt.gz |
| PGS004326 (PRS154_RA) |
PGP000560 | Zhang J et al. Environ Health Perspect (2023) |
Rheumatoid arthritis | rheumatoid arthritis | 154 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004326/ScoringFiles/PGS004326.txt.gz |
| PGS004699 (Non-HLA-GRS) |
PGP000603 | Loginovic P et al. Nat Commun (2024) |
Multiple sclerosis | multiple sclerosis | 307 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004699/ScoringFiles/PGS004699.txt.gz |
| PGS004700 (HLA-GRS) |
PGP000603 | Loginovic P et al. Nat Commun (2024) |
Multiple sclerosis | multiple sclerosis | 12 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004700/ScoringFiles/PGS004700.txt.gz |
| PGS004817 (RA_PRSmix_eur) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Rheumatoid Arthritis | rheumatoid arthritis | 786,048 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004817/ScoringFiles/PGS004817.txt.gz |
| PGS004818 (RA_PRSmix_sas) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Rheumatoid Arthritis | rheumatoid arthritis | 6,580,837 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004818/ScoringFiles/PGS004818.txt.gz |
| PGS004819 (RA_PRSmixPlus_eur) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Rheumatoid Arthritis | rheumatoid arthritis | 2,624,228 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004819/ScoringFiles/PGS004819.txt.gz |
| PGS004820 (RA_PRSmixPlus_sas) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Rheumatoid Arthritis | rheumatoid arthritis | 6,580,837 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004820/ScoringFiles/PGS004820.txt.gz |
| PGS004873 (INTERVENE_MegaPRS_RA) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 551,074 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004873/ScoringFiles/PGS004873.txt.gz | |
| PGS004876 (INTERVENE_MegaPRS_Appendicitis) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Appendicitis | appendicitis | 601,835 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004876/ScoringFiles/PGS004876.txt.gz |
| PGS004917 (wGRS) |
PGP000648 | Cui J et al. Arthritis Rheumatol (2020) |
Systemic lupus erythematosus | systemic lupus erythematosus | 97 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004917/ScoringFiles/PGS004917.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM000026 | PGS000017 (GPS_IBD) |
PSS000016| European Ancestry| 288,978 individuals |
PGP000006 | Khera AV et al. Nat Genet (2018) |
Reported Trait: Inflammatory bowel disease | — | AUROC: 0.63 [0.62, 0.64] | Nagelkerke’s R2 (estimate of variance explained by the PGS after covariate adjustment): 0.021 | age; sex; Ancestry PC 1-4; genotyping chip | — |
| PPM012874 | PGS000017 (GPS_IBD) |
PSS009588| European Ancestry| 1,433 individuals |
PGP000288 | Garcia-Etxebarria K et al. Sci Rep (2022) |Ext. |
Reported Trait: Inflammatory Bowel Disease | — | AUROC: 0.69 [0.66, 0.72] | — | — | — |
| PPM000262 | PGS000114 (GRS-JIA-20) |
PSS000179| European Ancestry| 3,513 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Juvenile Idiopathic Arthritis | OR: 1.838 [1.686, 2.007] | AUROC: 0.735 [0.712, 0.758] | — | sex, genetic PCs 1-10 | — |
| PPM000263 | PGS000114 (GRS-JIA-20) |
PSS000180| European Ancestry| 940 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Juvenile Idiopathic Arthritis | OR: 2.085 [1.773, 2.471] | AUROC: 0.738 [0.705, 0.77] | — | sex, genetic PCs 1-10 | — |
| PPM000260 | PGS000114 (GRS-JIA-20) |
PSS000179| European Ancestry| 3,513 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Juvenile Idiopathic Arthritis | OR: 1.831 [1.685, 1.991] | AUROC: 0.657 [0.631, 0.683] | — | — | — |
| PPM000261 | PGS000114 (GRS-JIA-20) |
PSS000180| European Ancestry| 940 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Juvenile Idiopathic Arthritis | OR: 2.008 [1.731, 2.345] | AUROC: 0.671 [0.635, 0.706] | — | — | — |
| PPM000577 | PGS000194 (G-PROB_Rapos) |
PSS000315| European Ancestry| 243 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.69 [0.63, 0.76] | — | RAN_Gprob | (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit) |
| PPM000571 | PGS000194 (G-PROB_Rapos) |
PSS000314| European Ancestry| 245 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.75 [0.68, 0.81] | — | G-PROB_Raneg | (Setting II: Assigning patient diagnoses based on medical records) |
| PPM000565 | PGS000194 (G-PROB_Rapos) |
PSS000322| Multi-ancestry (including European)| 1,211 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.69 [0.65, 0.72] | — | G-PROB_Raneg | (Setting I: Assigning patient diagnoses based on billing codes) |
| PPM000578 | PGS000195 (G-PROB_Raneg) |
PSS000315| European Ancestry| 243 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.69 [0.63, 0.76] | — | G-PROB_Rapos | (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit) |
| PPM000572 | PGS000195 (G-PROB_Raneg) |
PSS000314| European Ancestry| 245 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.75 [0.68, 0.81] | — | G-PROB_Rapos | (Setting II: Assigning patient diagnoses based on medical records) |
| PPM000566 | PGS000195 (G-PROB_Raneg) |
PSS000322| Multi-ancestry (including European)| 1,211 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.69 [0.65, 0.72] | — | G-PROB_Rapos | (Setting I: Assigning patient diagnoses based on billing codes) |
| PPM000579 | PGS000196 (G-PROB_SLE) |
PSS000319| European Ancestry| 243 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Systemic lupus erythematosus diagnosis in patient with arthritis | — | AUROC: 0.61 [0.27, 0.86] | — | — | (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit) |
| PPM000573 | PGS000196 (G-PROB_SLE) |
PSS000318| European Ancestry| 245 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Systemic lupus erythematosus diagnosis in patient with arthritis | — | AUROC: 0.79 [0.72, 0.85] | — | — | (Setting II: Assigning patient diagnoses based on medical records) |
| PPM000567 | PGS000196 (G-PROB_SLE) |
PSS000324| Multi-ancestry (including European)| 1,211 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Systemic lupus erythematosus diagnosis in patient with arthritis | — | AUROC: 0.74 [0.7, 0.78] | — | — | (Setting I: Assigning patient diagnoses based on billing codes) |
| PPM000581 | PGS000198 (G-PROB_PsA) |
PSS000313| European Ancestry| 243 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis | — | AUROC: 0.62 [0.48, 0.8] | — | — | (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit) |
| PPM000575 | PGS000198 (G-PROB_PsA) |
PSS000312| European Ancestry| 245 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis | — | AUROC: 0.71 [0.63, 0.82] | — | — | (Setting II: Assigning patient diagnoses based on medical records) |
| PPM000569 | PGS000198 (G-PROB_PsA) |
PSS000321| Multi-ancestry (including European)| 1,211 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis | — | AUROC: 0.61 [0.52, 0.69] | — | — | (Setting I: Assigning patient diagnoses based on billing codes) |
| PPM000874 | PGS000324 (GRS-JIA-ERA-20) |
PSS000432| European Ancestry| 594 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Enthesitis-related Arthritis | OR: 3.09 [2.07, 5.04] | AUROC: 0.93 [0.86, 0.99] | — | sex, genetic PCs 1-10 | — |
| PPM000873 | PGS000324 (GRS-JIA-ERA-20) |
PSS000429| European Ancestry| 3,020 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Enthesitis-related Arthritis | OR: 1.86 [1.61, 2.14] | AUROC: 0.75 [0.68, 0.82] | — | sex, genetic PCs 1-10 | — |
| PPM000867 | PGS000324 (GRS-JIA-ERA-20) |
PSS000429| European Ancestry| 3,020 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Enthesitis-related Arthritis | OR: 1.84 [1.6, 2.17] | AUROC: 0.7 [0.63, 0.77] | — | — | — |
| PPM000868 | PGS000324 (GRS-JIA-ERA-20) |
PSS000432| European Ancestry| 594 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Enthesitis-related Arthritis | OR: 2.99 [2.11, 4.54] | AUROC: 0.84 [0.71, 0.97] | — | — | — |
| PPM000875 | PGS000325 (GRS-JIA-Oli-20) |
PSS000430| European Ancestry| 3,157 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis | OR: 1.93 [1.75, 2.13] | AUROC: 0.8 [0.77, 0.84] | — | sex, genetic PCs 1-10 | — |
| PPM000876 | PGS000325 (GRS-JIA-Oli-20) |
PSS000433| European Ancestry| 737 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis | OR: 2.19 [1.81, 2.71] | AUROC: 0.79 [0.76, 0.83] | — | sex, genetic PCs 1-10 | — |
| PPM000869 | PGS000325 (GRS-JIA-Oli-20) |
PSS000430| European Ancestry| 3,157 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis | OR: 1.93 [1.76, 2.11] | AUROC: 0.77 [0.73, 0.8] | — | — | — |
| PPM000870 | PGS000325 (GRS-JIA-Oli-20) |
PSS000433| European Ancestry| 737 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis | OR: 2.24 [1.88, 2.71] | AUROC: 0.74 [0.7, 0.79] | — | — | — |
| PPM000878 | PGS000326 (GRS-JIA-RFN-20) |
PSS000434| European Ancestry| 653 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Rheumatoid-factor-negative Polyarthritis | OR: 1.71 [1.42, 2.07] | AUROC: 0.74 [0.68, 0.8] | — | sex, genetic PCs 1-10 | — |
| PPM000872 | PGS000326 (GRS-JIA-RFN-20) |
PSS000434| European Ancestry| 653 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Rheumatoid-factor-negative Polyarthritis | OR: 1.69 [1.42, 2.02] | AUROC: 0.66 [0.59, 0.73] | — | — | — |
| PPM000877 | PGS000326 (GRS-JIA-RFN-20) |
PSS000431| European Ancestry| 3,089 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Rheumatoid-factor-negative Polyarthritis | OR: 1.51 [1.35, 1.68] | AUROC: 0.76 [0.72, 0.8] | — | sex, genetic PCs 1-10 | — |
| PPM000871 | PGS000326 (GRS-JIA-RFN-20) |
PSS000431| European Ancestry| 3,089 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Rheumatoid-factor-negative Polyarthritis | OR: 1.48 [1.33, 1.64] | AUROC: 0.64 [0.59, 0.69] | — | — | — |
| PPM000882 | PGS000328 (GRS_SLE) |
PSS000438| European Ancestry| 15,383 individuals |
PGP000099 | Reid S et al. Ann Rheum Dis (2019) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.71 | Odds Ratio (OR; highest vs. lowest quartile): 7.48 [6.73, 8.32] | — | — |
| PPM000880 | PGS000328 (GRS_SLE) |
PSS000436| European Ancestry| 3,803 individuals |
PGP000099 | Reid S et al. Ann Rheum Dis (2019) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.78 | Odds Ratio (OR; highest vs. lowest quartile): 12.32 [9.53, 15.71] | — | — |
| PPM000883 | PGS000328 (GRS_SLE) |
PSS000436| European Ancestry| 3,803 individuals |
PGP000099 | Reid S et al. Ann Rheum Dis (2019) |
Reported Trait: Systemic Lupus damage score (SDI) | OR: 1.13 [1.03, 1.24] | — | Odds Ratio (OR; highest vs. lowest quartile): 1.47 [1.06, 2.04] | — | — |
| PPM000881 | PGS000328 (GRS_SLE) |
PSS000437| European Ancestry| 1,001 individuals |
PGP000099 | Reid S et al. Ann Rheum Dis (2019) |
Reported Trait: Systemic lupus erythematosus (onset before age 20) | — | AUROC: 0.83 | — | — | — |
| PPM000885 | PGS000328 (GRS_SLE) |
PSS000437| European Ancestry| 1,001 individuals |
PGP000099 | Reid S et al. Ann Rheum Dis (2019) |
Reported Trait: Nephritis in systemic lupus erythematosus patients | — | — | Hazard Ratio (HR; highest vs. lowest quartile): 2.53 [1.72, 3.71] | — | — |
| PPM000884 | PGS000328 (GRS_SLE) |
PSS000436| European Ancestry| 3,803 individuals |
PGP000099 | Reid S et al. Ann Rheum Dis (2019) |
Reported Trait: Systemic lupus erythematosus (age-at-onset) | — | — | Hazard Ratio (HR; highest vs. lowest quartile): 1.47 [1.22, 1.75] | — | — |
| PPM000971 | PGS000342 (wGRS_PsA) |
PSS000490| Ancestry Not Reported| 543 individuals |
PGP000111 | Smith MP et al. J Psoriasis Psoriatic Arthritis (2020) |
Reported Trait: Psoriatic arthritis | — | AUROC: 0.562 [0.506, 0.618] | — | — | — |
| PPM000972 | PGS000343 (wGRS_PsA_HLA) |
PSS000490| Ancestry Not Reported| 543 individuals |
PGP000111 | Smith MP et al. J Psoriasis Psoriatic Arthritis (2020) |
Reported Trait: Psoriatic arthritis | — | AUROC: 0.569 [0.513, 0.625] | — | — | — |
| PPM001761 | PGS000738 (CONFIRMED_PGS) |
PSS000907| European Ancestry| 4,008 individuals |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Reported Trait: Vitiligo | — | — | Odds Ratio (OR, top 20% vs remaining 80% of score distribution): 4.87 [4.21, 5.64] | — | — |
| PPM001762 | PGS000738 (CONFIRMED_PGS) |
PSS000907| European Ancestry| 4,008 individuals |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Reported Trait: Vitiligo | — | — | Odds Ratio (OR, top 10% vs remaining 90% of score distribution): 5.26 [4.42, 6.29] | — | — |
| PPM001763 | PGS000738 (CONFIRMED_PGS) |
PSS000907| European Ancestry| 4,008 individuals |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Reported Trait: Vitiligo | — | — | Odds Ratio (OR, top 10% vs remaining 95% of score distribution): 6.2 [4.96, 7.79] | — | — |
| PPM001764 | PGS000738 (CONFIRMED_PGS) |
PSS000907| European Ancestry| 4,008 individuals |
PGP000145 | Roberts GHL et al. Am J Hum Genet (2019) |
Reported Trait: Vitiligo | — | — | Odds Ratio (OR, top 1% vs remaining 99% of score distribution): 8.79 [5.85, 13.78] | — | — |
| PPM018437 | PGS000738 (CONFIRMED_PGS) |
PSS010969| European Ancestry| 4,945 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Fitzpatrick scale | β: 0.02234 | — | R²: 0.02897 | — | — |
| PPM018438 | PGS000738 (CONFIRMED_PGS) |
PSS010968| European Ancestry| 4,702 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Red hair | β: 0.69478 | — | pseudo R²: 0.03857 | — | — |
| PPM018435 | PGS000738 (CONFIRMED_PGS) |
PSS010977| European Ancestry| 4,987 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Freckles | β: -0.04382 | — | R²: 0.02103 | — | — |
| PPM018436 | PGS000738 (CONFIRMED_PGS) |
PSS010974| European Ancestry| 4,979 individuals |
PGP000467 | Farré X et al. Genes (Basel) (2023) |Ext. |
Reported Trait: Phototype score | β: 0.4039 | — | R²: 0.03252 | — | — |
| PPM001919 | PGS000754 (PRS_SLE) |
PSS000963| East Asian Ancestry| 2,589 individuals |
PGP000160 | Wang YF et al. Nat Commun (2021) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.76 [0.74, 0.78] | — | — | — |
| PPM001920 | PGS000754 (PRS_SLE) |
PSS000960| European Ancestry| 1,340 individuals |
PGP000160 | Wang YF et al. Nat Commun (2021) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.65 | — | — | — |
| PPM001921 | PGS000754 (PRS_SLE) |
PSS000961| European Ancestry| 7,733 individuals |
PGP000160 | Wang YF et al. Nat Commun (2021) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.65 | — | — | — |
| PPM001922 | PGS000754 (PRS_SLE) |
PSS000962| European Ancestry| 1,112 individuals |
PGP000160 | Wang YF et al. Nat Commun (2021) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.62 | — | — | — |
| PPM002076 | PGS000754 (PRS_SLE) |
PSS001027| Additional Asian Ancestries| 3,996 individuals |
PGP000188 | Tangtanatakul P et al. Arthritis Res Ther (2020) |Ext. |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.76 | — | — | — |
| PPM001935 | PGS000760 (VIT) |
PSS000970| European Ancestry| 1,584 individuals |
PGP000164 | Khan Z et al. Nat Commun (2021) |
Reported Trait: anti-PD-L1 induced hypothyroidism in cancer patients | HR: 1.41 [1.22, 1.61] | — | meta-analysis p-value: 1.10e-06 | 5 genotype PCs | — |
| PPM001996 | PGS000771 (GRS95_SLEmain) |
PSS000994| European Ancestry| 524 individuals |
PGP000178 | Chen L et al. Hum Mol Genet (2020) |
Reported Trait: Renal disease age of onset | — | AUROC: 0.576 [0.518, 0.634] | — | — | Renal disease is used as a proxy for systemic lupus erythematosus severity |
| PPM001998 | PGS000771 (GRS95_SLEmain) |
PSS000994| European Ancestry| 524 individuals |
PGP000178 | Chen L et al. Hum Mol Genet (2020) |
Reported Trait: Renal disease age of onset | — | — | Odds Ratio (OR, top 20% vs bottom 20%): 3.155 [1.623, 6.133] | — | Renal disease is used as a proxy for systemic lupus erythematosus severity |
| PPM001997 | PGS000772 (GRS95_SLEgen) |
PSS000993| European Ancestry| 3,101 individuals |
PGP000178 | Chen L et al. Hum Mol Genet (2020) |
Reported Trait: Renal disease | — | — | Odds Ratio (OR, top 20% vs bottom 20%): 1.578 [1.25, 1.991] | — | Renal disease is used as a proxy for systemic lupus erythematosus severity |
| PPM002100 | PGS000803 (wGRS41_SLE) |
PSS001038| European Ancestry| 47,904 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Lupus (localised and systemic) | OR: 1.73 [1.62, 1.85] β: 0.546 (0.034) |
— | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002101 | PGS000803 (wGRS41_SLE) |
PSS001043| European Ancestry| 18,722 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Lupus (localised and systemic) | OR: 1.82 [1.66, 2.0] | — | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002102 | PGS000803 (wGRS41_SLE) |
PSS001035| European Ancestry| 47,917 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Systemic lupus erythematosus | OR: 1.71 [1.6, 1.82] β: 0.534 (0.034) |
— | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002103 | PGS000803 (wGRS41_SLE) |
PSS001040| European Ancestry| 18,698 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Systemic lupus erythematosus | OR: 1.86 [1.69, 2.04] | — | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002104 | PGS000803 (wGRS41_SLE) |
PSS001037| European Ancestry| 50,429 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Erythematous conditions | OR: 1.28 [1.22, 1.34] β: 0.246 (0.024) |
— | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002105 | PGS000803 (wGRS41_SLE) |
PSS001042| European Ancestry| 21,474 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Erythematous conditions | OR: 1.08 [1.04, 1.13] | — | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002106 | PGS000803 (wGRS41_SLE) |
PSS001034| European Ancestry| 47,321 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Cutaneous lupus erythematosus | OR: 1.79 [1.54, 2.08] β: 0.582 (0.078) |
— | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002107 | PGS000803 (wGRS41_SLE) |
PSS001039| European Ancestry| 18,422 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Cutaneous lupus erythematosus | OR: 2.02 [1.71, 2.4] | — | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002108 | PGS000803 (wGRS41_SLE) |
PSS001036| European Ancestry| 40,528 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Type 1 diabetes | OR: 1.11 [1.06, 1.17] β: 0.108 (0.024) |
— | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002109 | PGS000803 (wGRS41_SLE) |
PSS001041| European Ancestry| 19,191 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Type 1 diabetes | OR: 1.11 [1.05, 1.18] | — | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002110 | PGS000803 (wGRS41_SLE) |
PSS001036| European Ancestry| 40,528 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Type 1 diabetes with renal manifestations | OR: 1.41 [1.26, 1.59] β: 0.346 (0.06) |
— | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002111 | PGS000803 (wGRS41_SLE) |
PSS001041| European Ancestry| 19,191 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Type 1 diabetes with renal manifestations | OR: 1.38 [1.19, 1.6] | — | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002112 | PGS000803 (wGRS41_SLE) |
PSS001036| European Ancestry| 40,528 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Type 1 diabetes with opthalmic manifestations | OR: 1.32 [1.16, 1.5] β: 0.275 (0.065) |
— | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002113 | PGS000803 (wGRS41_SLE) |
PSS001041| European Ancestry| 19,191 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Type 1 diabetes with opthalmic manifestations | OR: 1.34 [1.18, 1.52] | — | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002114 | PGS000803 (wGRS41_SLE) |
PSS001036| European Ancestry| 40,528 individuals |
PGP000192 | Kawai VK et al. Lupus (2021) |
Reported Trait: Type 1 diabetes with neurological manifestations | OR: 1.16 [1.06, 1.28] β: 0.151 (0.047) |
— | — | PCs(1-5), median age in the electronic health record, sex | — |
| PPM002137 | PGS000809 (PRS127_MS) |
PSS001050| European Ancestry| 725 individuals |
PGP000194 | Barnes CLK et al. Eur J Hum Genet (2021) |
Reported Trait: Multiple sclerosis | β: 0.6 | AUROC: 0.705 (0.029) | R²: 0.07 | Age, sex, PCs(1-2) | — |
| PPM002138 | PGS000809 (PRS127_MS) |
PSS001051| European Ancestry| 656 individuals |
PGP000194 | Barnes CLK et al. Eur J Hum Genet (2021) |
Reported Trait: Multiple sclerosis | β: 0.59 | AUROC: 0.762 (0.055) | R²: 0.075 | Age, sex, PCs(1-2) | — |
| PPM002139 | PGS000809 (PRS127_MS) |
PSS001049| European Ancestry| 8,370 individuals |
PGP000194 | Barnes CLK et al. Eur J Hum Genet (2021) |
Reported Trait: Multiple Sclerosis | β: 0.63 | AUROC: 0.765 (0.042) | R²: 0.069 | Age, sex, PCs(1-2) | — |
| PPM007968 | PGS001042 (GBE_HC645) |
PSS004565| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE thyrotoxicosis [hyperthyroidism] | — | AUROC: 0.74292 [0.70274, 0.7831] | R²: 0.0808 Incremental AUROC (full-covars): -0.001 PGS R2 (no covariates): 0.00441 PGS AUROC (no covariates): 0.55406 [0.50519, 0.60292] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007969 | PGS001042 (GBE_HC645) |
PSS004566| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE thyrotoxicosis [hyperthyroidism] | — | AUROC: 0.64568 [0.56662, 0.72474] | R²: 0.04341 Incremental AUROC (full-covars): 0.0279 PGS R2 (no covariates): 0.02341 PGS AUROC (no covariates): 0.6179 [0.53755, 0.69825] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007970 | PGS001042 (GBE_HC645) |
PSS004567| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE thyrotoxicosis [hyperthyroidism] | — | AUROC: 0.69253 [0.66505, 0.72] | R²: 0.0468 Incremental AUROC (full-covars): 0.03643 PGS R2 (no covariates): 0.01594 PGS AUROC (no covariates): 0.61209 [0.58178, 0.6424] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007971 | PGS001042 (GBE_HC645) |
PSS004568| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE thyrotoxicosis [hyperthyroidism] | — | AUROC: 0.68899 [0.63846, 0.73951] | R²: 0.04589 Incremental AUROC (full-covars): 0.03955 PGS R2 (no covariates): 0.01668 PGS AUROC (no covariates): 0.60594 [0.54869, 0.66319] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007972 | PGS001042 (GBE_HC645) |
PSS004569| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE thyrotoxicosis [hyperthyroidism] | — | AUROC: 0.71296 [0.69708, 0.72884] | R²: 0.05914 Incremental AUROC (full-covars): 0.04673 PGS R2 (no covariates): 0.02359 PGS AUROC (no covariates): 0.63392 [0.61562, 0.65223] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007973 | PGS001043 (GBE_HC55) |
PSS004526| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Hyperthyroidism/thyrotoxicosis | — | AUROC: 0.73999 [0.69812, 0.78186] | R²: 0.07663 Incremental AUROC (full-covars): -0.00598 PGS R2 (no covariates): 0.00164 PGS AUROC (no covariates): 0.53513 [0.48316, 0.5871] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007974 | PGS001043 (GBE_HC55) |
PSS004527| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Hyperthyroidism/thyrotoxicosis | — | AUROC: 0.62359 [0.53601, 0.71117] | R²: 0.03132 Incremental AUROC (full-covars): 0.0205 PGS R2 (no covariates): 0.01311 PGS AUROC (no covariates): 0.58858 [0.50442, 0.67274] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007975 | PGS001043 (GBE_HC55) |
PSS004528| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Hyperthyroidism/thyrotoxicosis | — | AUROC: 0.69729 [0.66674, 0.72784] | R²: 0.04646 Incremental AUROC (full-covars): 0.03676 PGS R2 (no covariates): 0.01638 PGS AUROC (no covariates): 0.61845 [0.58525, 0.65166] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007976 | PGS001043 (GBE_HC55) |
PSS004529| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Hyperthyroidism/thyrotoxicosis | — | AUROC: 0.68797 [0.63675, 0.7392] | R²: 0.04145 Incremental AUROC (full-covars): 0.04372 PGS R2 (no covariates): 0.01807 PGS AUROC (no covariates): 0.60983 [0.54762, 0.67204] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007977 | PGS001043 (GBE_HC55) |
PSS004530| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Hyperthyroidism/thyrotoxicosis | — | AUROC: 0.71366 [0.6965, 0.73082] | R²: 0.0566 Incremental AUROC (full-covars): 0.04641 PGS R2 (no covariates): 0.02158 PGS AUROC (no covariates): 0.6323 [0.61251, 0.6521] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008289 | PGS001110 (GBE_HC1209) |
PSS004183| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE reactive arthropathies | — | AUROC: 0.9594 [0.92062, 0.99818] | R²: 0.17918 Incremental AUROC (full-covars): 0.00395 PGS R2 (no covariates): 0.00991 PGS AUROC (no covariates): 0.72061 [0.49213, 0.9491] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008290 | PGS001110 (GBE_HC1209) |
PSS004185| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE reactive arthropathies | — | AUROC: 0.77096 [0.63921, 0.90271] | R²: 0.09743 Incremental AUROC (full-covars): 0.03274 PGS R2 (no covariates): 0.03411 PGS AUROC (no covariates): 0.65137 [0.47674, 0.826] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008291 | PGS001110 (GBE_HC1209) |
PSS004186| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE reactive arthropathies | — | AUROC: 0.94552 [0.83969, 1.0] | R²: 0.25627 Incremental AUROC (full-covars): 0.00045 PGS R2 (no covariates): 0.00071 PGS AUROC (no covariates): 0.67786 [0.66768, 0.68805] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008292 | PGS001110 (GBE_HC1209) |
PSS004187| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE reactive arthropathies | — | AUROC: 0.6839 [0.58647, 0.78132] | R²: 0.03053 Incremental AUROC (full-covars): 0.07922 PGS R2 (no covariates): 0.02879 PGS AUROC (no covariates): 0.66167 [0.54859, 0.77475] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008840 | PGS001267 (GBE_HC422) |
PSS004486| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.86744 [0.75569, 0.97918] | R²: 0.1463 Incremental AUROC (full-covars): -0.00062 PGS R2 (no covariates): 0.00216 PGS AUROC (no covariates): 0.4722 [0.12421, 0.82018] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008841 | PGS001267 (GBE_HC422) |
PSS004487| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.98913 [0.972, 1.0] | R²: 0.44316 Incremental AUROC (full-covars): 0.0423 PGS R2 (no covariates): 0.24382 PGS AUROC (no covariates): 0.81698 [0.46329, 1.0] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008842 | PGS001267 (GBE_HC422) |
PSS004488| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.73638 [0.67151, 0.80124] | R²: 0.10414 Incremental AUROC (full-covars): 0.06004 PGS R2 (no covariates): 0.07222 PGS AUROC (no covariates): 0.67545 [0.60736, 0.74353] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008843 | PGS001267 (GBE_HC422) |
PSS004489| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.73535 [0.61203, 0.85867] | R²: 0.03713 Incremental AUROC (full-covars): -0.01782 PGS R2 (no covariates): 0.00902 PGS AUROC (no covariates): 0.42181 [0.29024, 0.55338] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008844 | PGS001267 (GBE_HC422) |
PSS004490| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.74328 [0.70673, 0.77983] | R²: 0.10925 Incremental AUROC (full-covars): 0.12994 PGS R2 (no covariates): 0.09877 PGS AUROC (no covariates): 0.72651 [0.68965, 0.76337] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008845 | PGS001268 (GBE_HC1242) |
PSS004228| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.86811 [0.75774, 0.97849] | R²: 0.14598 Incremental AUROC (full-covars): 6e-05 PGS R2 (no covariates): 0.00104 PGS AUROC (no covariates): 0.48424 [0.12443, 0.84406] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008846 | PGS001268 (GBE_HC1242) |
PSS004229| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.99148 [0.9789, 1.0] | R²: 0.44858 Incremental AUROC (full-covars): 0.04465 PGS R2 (no covariates): 0.23755 PGS AUROC (no covariates): 0.81257 [0.45025, 1.0] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008847 | PGS001268 (GBE_HC1242) |
PSS004230| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.73336 [0.66901, 0.79772] | R²: 0.10217 Incremental AUROC (full-covars): 0.0575 PGS R2 (no covariates): 0.06991 PGS AUROC (no covariates): 0.67405 [0.607, 0.74111] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008848 | PGS001268 (GBE_HC1242) |
PSS004231| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.73282 [0.61573, 0.84991] | R²: 0.03979 Incremental AUROC (full-covars): -0.01963 PGS R2 (no covariates): 0.00774 PGS AUROC (no covariates): 0.4297 [0.29438, 0.56502] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008849 | PGS001268 (GBE_HC1242) |
PSS004232| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.74878 [0.71314, 0.78442] | R²: 0.115 Incremental AUROC (full-covars): 0.12686 PGS R2 (no covariates): 0.10232 PGS AUROC (no covariates): 0.7346 [0.69884, 0.77037] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008850 | PGS001270 (GBE_HC151) |
PSS004273| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Multiple sclerosis | — | AUROC: 0.78603 [0.68344, 0.88862] | R²: 0.07124 Incremental AUROC (full-covars): -0.04449 PGS R2 (no covariates): 0.02639 PGS AUROC (no covariates): 0.35945 [0.2174, 0.5015] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008851 | PGS001270 (GBE_HC151) |
PSS004274| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Multiple sclerosis | — | AUROC: 0.65766 [0.60651, 0.7088] | R²: 0.02306 Incremental AUROC (full-covars): 0.0559 PGS R2 (no covariates): 0.01225 PGS AUROC (no covariates): 0.61627 [0.56233, 0.67022] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008852 | PGS001270 (GBE_HC151) |
PSS004275| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Multiple sclerosis | — | AUROC: 0.9739 [0.9358, 1.0] | R²: 0.3229 Incremental AUROC (full-covars): 0.01955 PGS R2 (no covariates): 0.02901 PGS AUROC (no covariates): 0.64875 [0.24603, 1.0] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008853 | PGS001270 (GBE_HC151) |
PSS004276| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Multiple sclerosis | — | AUROC: 0.69658 [0.66502, 0.72814] | R²: 0.04105 Incremental AUROC (full-covars): 0.08355 PGS R2 (no covariates): 0.02904 PGS AUROC (no covariates): 0.65856 [0.62428, 0.69284] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008854 | PGS001271 (GBE_HC810) |
PSS004637| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE multiple sclerosis | — | AUROC: 0.8033 [0.6935, 0.91311] | PGS R2 (no covariates): 0.01095 R²: 0.10788 Incremental AUROC (full-covars): -0.03509 PGS AUROC (no covariates): 0.39974 [0.23738, 0.56211] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008855 | PGS001271 (GBE_HC810) |
PSS004639| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE multiple sclerosis | — | AUROC: 0.65561 [0.60622, 0.705] | R²: 0.02347 Incremental AUROC (full-covars): 0.05454 PGS R2 (no covariates): 0.01258 PGS AUROC (no covariates): 0.61601 [0.56326, 0.66875] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008856 | PGS001271 (GBE_HC810) |
PSS004640| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE multiple sclerosis | — | AUROC: 0.97595 [0.94159, 1.0] | R²: 0.33555 Incremental AUROC (full-covars): 0.01648 PGS R2 (no covariates): 0.01091 PGS AUROC (no covariates): 0.55629 [0.19512, 0.91745] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008857 | PGS001271 (GBE_HC810) |
PSS004641| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE multiple sclerosis | — | AUROC: 0.6895 [0.65926, 0.71974] | R²: 0.03906 Incremental AUROC (full-covars): 0.07145 PGS R2 (no covariates): 0.02562 PGS AUROC (no covariates): 0.64688 [0.61364, 0.68013] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008933 | PGS001287 (GBE_HC91) |
PSS004706| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.98006 [0.94602, 1.0] | Incremental AUROC (full-covars): 0.00516 R²: 0.29301 PGS R2 (no covariates): 0.01017 PGS AUROC (no covariates): 0.72132 [0.63231, 0.81034] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008934 | PGS001287 (GBE_HC91) |
PSS004707| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.99354 [0.98059, 1.0] | R²: 0.5357 Incremental AUROC (full-covars): -0.00088 PGS R2 (no covariates): 0.00227 PGS AUROC (no covariates): 0.47826 [0.0, 0.96911] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008935 | PGS001287 (GBE_HC91) |
PSS004708| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.72814 [0.67154, 0.78475] | R²: 0.05154 Incremental AUROC (full-covars): 0.08346 PGS R2 (no covariates): 0.0335 PGS AUROC (no covariates): 0.67648 [0.61155, 0.7414] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008936 | PGS001287 (GBE_HC91) |
PSS004709| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.71827 [0.61363, 0.82292] | R²: 0.04395 Incremental AUROC (full-covars): 0.00838 PGS R2 (no covariates): 0.00229 PGS AUROC (no covariates): 0.56943 [0.44876, 0.69011] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008937 | PGS001287 (GBE_HC91) |
PSS004710| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.6376 [0.60073, 0.67447] | R²: 0.02161 Incremental AUROC (full-covars): 0.0945 PGS R2 (no covariates): 0.02111 PGS AUROC (no covariates): 0.63567 [0.598, 0.67334] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008938 | PGS001288 (GBE_HC95) |
PSS004741| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Inflammatory bowel disease | — | AUROC: 0.64251 [0.54711, 0.73791] | R²: 0.05914 Incremental AUROC (full-covars): 0.00245 PGS R2 (no covariates): 0.00027 PGS AUROC (no covariates): 0.52101 [0.42335, 0.61867] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008939 | PGS001288 (GBE_HC95) |
PSS004742| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Inflammatory bowel disease | — | AUROC: 0.89429 [0.79091, 0.99767] | R²: 0.2051 Incremental AUROC (full-covars): -0.0033 PGS R2 (no covariates): 0.0 PGS AUROC (no covariates): 0.48687 [0.28135, 0.6924] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008940 | PGS001288 (GBE_HC95) |
PSS004743| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Inflammatory bowel disease | — | AUROC: 0.63478 [0.60168, 0.66787] | R²: 0.02287 Incremental AUROC (full-covars): 0.02492 PGS R2 (no covariates): 0.0102 PGS AUROC (no covariates): 0.58475 [0.55242, 0.61708] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008941 | PGS001288 (GBE_HC95) |
PSS004744| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Inflammatory bowel disease | — | AUROC: 0.66934 [0.62525, 0.71343] | R²: 0.03759 Incremental AUROC (full-covars): 0.004 PGS R2 (no covariates): 0.00311 PGS AUROC (no covariates): 0.55448 [0.50125, 0.6077] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008942 | PGS001288 (GBE_HC95) |
PSS004745| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Inflammatory bowel disease | — | AUROC: 0.59461 [0.57544, 0.61378] | R²: 0.01221 Incremental AUROC (full-covars): 0.06405 PGS R2 (no covariates): 0.01191 PGS AUROC (no covariates): 0.59586 [0.5768, 0.61492] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009024 | PGS001306 (GBE_HC201) |
PSS004339| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ulcerative colitis | — | AUROC: 0.62904 [0.5093, 0.74878] | R²: 0.04535 Incremental AUROC (full-covars): -0.00864 PGS R2 (no covariates): 0.00044 PGS AUROC (no covariates): 0.51081 [0.37987, 0.64174] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009025 | PGS001306 (GBE_HC201) |
PSS004340| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ulcerative colitis | — | AUROC: 0.89429 [0.79357, 0.99502] | R²: 0.20499 Incremental AUROC (full-covars): -0.0033 PGS R2 (no covariates): 2e-05 PGS AUROC (no covariates): 0.49111 [0.35854, 0.62368] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009026 | PGS001306 (GBE_HC201) |
PSS004341| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ulcerative colitis | — | AUROC: 0.66162 [0.6277, 0.69554] | R²: 0.03336 Incremental AUROC (full-covars): 0.04247 PGS R2 (no covariates): 0.02036 PGS AUROC (no covariates): 0.63006 [0.5958, 0.66432] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009027 | PGS001306 (GBE_HC201) |
PSS004342| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ulcerative colitis | — | AUROC: 0.67522 [0.62537, 0.72506] | R²: 0.03696 Incremental AUROC (full-covars): 0.01011 PGS R2 (no covariates): 0.00545 PGS AUROC (no covariates): 0.56552 [0.50815, 0.62289] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009028 | PGS001306 (GBE_HC201) |
PSS004343| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ulcerative colitis | — | AUROC: 0.6157 [0.59481, 0.63659] | PGS R2 (no covariates): 0.0193 R²: 0.01676 Incremental AUROC (full-covars): 0.08728 PGS AUROC (no covariates): 0.62452 [0.60374, 0.6453] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009029 | PGS001307 (GBE_HC1102) |
PSS004119| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ulcerative colitis | — | AUROC: 0.62873 [0.51002, 0.74744] | R²: 0.04344 Incremental AUROC (full-covars): -0.00895 PGS R2 (no covariates): 0.00027 PGS AUROC (no covariates): 0.50641 [0.39121, 0.62161] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009030 | PGS001307 (GBE_HC1102) |
PSS004120| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ulcerative colitis | — | AUROC: 0.89582 [0.79576, 0.99588] | R²: 0.20607 Incremental AUROC (full-covars): -0.00177 PGS R2 (no covariates): 0.00203 PGS AUROC (no covariates): 0.55433 [0.4473, 0.66136] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009031 | PGS001307 (GBE_HC1102) |
PSS004121| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ulcerative colitis | — | AUROC: 0.65578 [0.62353, 0.68804] | R²: 0.03272 Incremental AUROC (full-covars): 0.04212 PGS R2 (no covariates): 0.0169 PGS AUROC (no covariates): 0.6106 [0.57717, 0.64402] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009032 | PGS001307 (GBE_HC1102) |
PSS004122| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ulcerative colitis | — | AUROC: 0.66008 [0.61042, 0.70974] | R²: 0.03192 Incremental AUROC (full-covars): 0.00203 PGS R2 (no covariates): 0.0036 PGS AUROC (no covariates): 0.55808 [0.506, 0.61016] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009033 | PGS001307 (GBE_HC1102) |
PSS004123| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ulcerative colitis | — | AUROC: 0.63965 [0.62036, 0.65895] | R²: 0.02376 Incremental AUROC (full-covars): 0.1085 PGS R2 (no covariates): 0.02383 PGS AUROC (no covariates): 0.63847 [0.61861, 0.65833] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009034 | PGS001308 (GBE_HC321) |
PSS004437| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Sjogren's syndrome/sicca syndrome | — | AUROC: 0.79846 [0.71474, 0.88218] | R²: 0.07345 Incremental AUROC (full-covars): 0.0079 PGS R2 (no covariates): 0.01471 PGS AUROC (no covariates): 0.59027 [0.45551, 0.72504] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009035 | PGS001308 (GBE_HC321) |
PSS004438| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Sjogren's syndrome/sicca syndrome | — | AUROC: 0.75824 [0.55089, 0.96558] | R²: 0.05686 Incremental AUROC (full-covars): 0.00691 PGS R2 (no covariates): 0.0091 PGS AUROC (no covariates): 0.69794 [0.63241, 0.76347] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009036 | PGS001308 (GBE_HC321) |
PSS004439| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Sjogren's syndrome/sicca syndrome | — | AUROC: 0.77174 [0.71988, 0.82361] | R²: 0.07435 Incremental AUROC (full-covars): 0.01461 PGS R2 (no covariates): 0.01453 PGS AUROC (no covariates): 0.65693 [0.58901, 0.72485] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009037 | PGS001308 (GBE_HC321) |
PSS004440| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Sjogren's syndrome/sicca syndrome | — | AUROC: 0.8014 [0.74455, 0.85826] | R²: 0.08893 Incremental AUROC (full-covars): 0.00953 PGS R2 (no covariates): 0.03189 PGS AUROC (no covariates): 0.61034 [0.48809, 0.73259] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009038 | PGS001308 (GBE_HC321) |
PSS004441| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Sjogren's syndrome/sicca syndrome | — | AUROC: 0.73313 [0.69647, 0.76978] | R²: 0.04771 Incremental AUROC (full-covars): 0.01551 PGS R2 (no covariates): 0.01074 PGS AUROC (no covariates): 0.60303 [0.55292, 0.65315] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009039 | PGS001309 (GBE_HC1212) |
PSS004193| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.69751 [0.65515, 0.73988] | R²: 0.05129 Incremental AUROC (full-covars): -0.00017 PGS R2 (no covariates): 0.00056 PGS AUROC (no covariates): 0.52591 [0.47486, 0.57696] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009040 | PGS001309 (GBE_HC1212) |
PSS004194| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.67331 [0.56418, 0.78244] | R²: 0.07058 Incremental AUROC (full-covars): -0.02511 PGS R2 (no covariates): 0.0 PGS AUROC (no covariates): 0.50714 [0.3797, 0.63457] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009041 | PGS001309 (GBE_HC1212) |
PSS004195| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.6872 [0.66167, 0.71273] | R²: 0.04826 Incremental AUROC (full-covars): 0.02601 PGS R2 (no covariates): 0.01537 PGS AUROC (no covariates): 0.59782 [0.56885, 0.62679] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009042 | PGS001309 (GBE_HC1212) |
PSS004196| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.70239 [0.66722, 0.73755] | R²: 0.06164 Incremental AUROC (full-covars): -0.00362 PGS R2 (no covariates): 0.00158 PGS AUROC (no covariates): 0.53481 [0.4923, 0.57731] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009043 | PGS001309 (GBE_HC1212) |
PSS004197| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.66538 [0.65101, 0.67976] | R²: 0.03893 Incremental AUROC (full-covars): 0.03207 PGS R2 (no covariates): 0.01495 PGS AUROC (no covariates): 0.59784 [0.582, 0.61368] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009044 | PGS001310 (GBE_HC430) |
PSS004491| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.70522 [0.66309, 0.74736] | R²: 0.0544 Incremental AUROC (full-covars): 0.00203 PGS R2 (no covariates): 0.00109 PGS AUROC (no covariates): 0.53147 [0.47999, 0.58294] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009045 | PGS001310 (GBE_HC430) |
PSS004492| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.66116 [0.54578, 0.77655] | R²: 0.06929 Incremental AUROC (full-covars): -0.02514 PGS R2 (no covariates): 0.00033 PGS AUROC (no covariates): 0.52178 [0.38366, 0.6599] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009046 | PGS001310 (GBE_HC430) |
PSS004493| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.68857 [0.6632, 0.71393] | R²: 0.04919 Incremental AUROC (full-covars): 0.02092 PGS R2 (no covariates): 0.01316 PGS AUROC (no covariates): 0.58714 [0.55751, 0.61676] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009047 | PGS001310 (GBE_HC430) |
PSS004494| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.70402 [0.66905, 0.73899] | R²: 0.06207 Incremental AUROC (full-covars): -0.0019 PGS R2 (no covariates): 0.00142 PGS AUROC (no covariates): 0.53137 [0.48984, 0.57291] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009048 | PGS001310 (GBE_HC430) |
PSS004495| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.66508 [0.65049, 0.67967] | R²: 0.03894 Incremental AUROC (full-covars): 0.03077 PGS R2 (no covariates): 0.01509 PGS AUROC (no covariates): 0.60018 [0.58428, 0.61607] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009049 | PGS001311 (GBE_HC1211) |
PSS004188| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seropositive rheumatoid arthritis | — | AUROC: 0.90345 [0.82233, 0.98457] | R²: 0.16794 Incremental AUROC (full-covars): -0.00669 PGS R2 (no covariates): 0.01613 PGS AUROC (no covariates): 0.39273 [0.11505, 0.67041] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009050 | PGS001311 (GBE_HC1211) |
PSS004190| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seropositive rheumatoid arthritis | — | AUROC: 0.76787 [0.6839, 0.85184] | R²: 0.08412 Incremental AUROC (full-covars): 0.0418 PGS R2 (no covariates): 0.05847 PGS AUROC (no covariates): 0.73164 [0.63667, 0.82662] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009051 | PGS001311 (GBE_HC1211) |
PSS004191| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seropositive rheumatoid arthritis | — | AUROC: 0.76865 [0.6608, 0.87651] | R²: 0.08089 Incremental AUROC (full-covars): -0.00731 PGS R2 (no covariates): 0.00567 PGS AUROC (no covariates): 0.50626 [0.35145, 0.66107] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009052 | PGS001311 (GBE_HC1211) |
PSS004192| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seropositive rheumatoid arthritis | — | AUROC: 0.73785 [0.69634, 0.77936] | R²: 0.05309 Incremental AUROC (full-covars): 0.09202 PGS R2 (no covariates): 0.04612 PGS AUROC (no covariates): 0.7072 [0.65945, 0.75495] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009137 | PGS001330 (GBE_HC1101) |
PSS004114| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE crohn's disease [regional enteritis] | — | AUROC: 0.66243 [0.55234, 0.77252] | R²: 0.05286 Incremental AUROC (full-covars): -0.02175 PGS R2 (no covariates): 0.00138 PGS AUROC (no covariates): 0.46272 [0.36718, 0.55826] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009138 | PGS001330 (GBE_HC1101) |
PSS004115| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE crohn's disease [regional enteritis] | — | AUROC: 0.86369 [0.7806, 0.94678] | R²: 0.13339 Incremental AUROC (full-covars): 0.0 PGS R2 (no covariates): 0.14319 PGS AUROC (no covariates): 0.10664 [0.0, 0.28372] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009139 | PGS001330 (GBE_HC1101) |
PSS004116| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE crohn's disease [regional enteritis] | — | AUROC: 0.60269 [0.55209, 0.65328] | R²: 0.01102 Incremental AUROC (full-covars): 0.02413 PGS R2 (no covariates): 0.00621 PGS AUROC (no covariates): 0.57593 [0.52318, 0.62867] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009140 | PGS001330 (GBE_HC1101) |
PSS004117| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE crohn's disease [regional enteritis] | — | AUROC: 0.69933 [0.63548, 0.76318] | R²: 0.0344 Incremental AUROC (full-covars): 0.00201 PGS R2 (no covariates): 0.00147 PGS AUROC (no covariates): 0.53846 [0.46042, 0.6165] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009141 | PGS001330 (GBE_HC1101) |
PSS004118| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE crohn's disease [regional enteritis] | — | AUROC: 0.55852 [0.52842, 0.58862] | R²: 0.00474 Incremental AUROC (full-covars): 0.07412 PGS R2 (no covariates): 0.00669 PGS AUROC (no covariates): 0.5714 [0.54073, 0.60207] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009142 | PGS001331 (GBE_HC322) |
PSS004442| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Crohns disease | — | AUROC: 0.65892 [0.54485, 0.77299] | R²: 0.05502 Incremental AUROC (full-covars): -0.02526 PGS R2 (no covariates): 4e-05 PGS AUROC (no covariates): 0.49152 [0.37858, 0.60446] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009143 | PGS001331 (GBE_HC322) |
PSS004444| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Crohns disease | — | AUROC: 0.61269 [0.55802, 0.66736] | R²: 0.01161 Incremental AUROC (full-covars): 0.02705 PGS R2 (no covariates): 0.00677 PGS AUROC (no covariates): 0.57919 [0.52051, 0.63786] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009144 | PGS001331 (GBE_HC322) |
PSS004445| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Crohns disease | — | AUROC: 0.71 [0.64649, 0.7735] | R²: 0.03928 Incremental AUROC (full-covars): 0.01378 PGS R2 (no covariates): 0.00366 PGS AUROC (no covariates): 0.56349 [0.47905, 0.64793] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009145 | PGS001331 (GBE_HC322) |
PSS004446| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Crohns disease | — | AUROC: 0.56362 [0.53297, 0.59427] | R²: 0.00529 Incremental AUROC (full-covars): 0.06267 PGS R2 (no covariates): 0.0063 PGS AUROC (no covariates): 0.57326 [0.54246, 0.60406] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005205 | PGS001369 (GBE_HC1090) |
PSS004099| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE acute appendicitis | — | AUROC: 0.62041 [0.53518, 0.70564] | R²: 0.03016 Incremental AUROC (full-covars): -0.00198 PGS R2 (no covariates): 0.00105 PGS AUROC (no covariates): 0.47489 [0.37525, 0.57453] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005206 | PGS001369 (GBE_HC1090) |
PSS004100| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE acute appendicitis | — | AUROC: 0.8493 [0.77779, 0.9208] | R²: 0.14577 Incremental AUROC (full-covars): 0.00105 PGS R2 (no covariates): 0.00332 PGS AUROC (no covariates): 0.51032 [0.33889, 0.68176] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005207 | PGS001369 (GBE_HC1090) |
PSS004101| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE acute appendicitis | — | AUROC: 0.56849 [0.52835, 0.60862] | R²: 0.00702 Incremental AUROC (full-covars): -0.00219 PGS R2 (no covariates): 0.0 PGS AUROC (no covariates): 0.49616 [0.45378, 0.53854] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005208 | PGS001369 (GBE_HC1090) |
PSS004102| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE acute appendicitis | — | AUROC: 0.72977 [0.65912, 0.80042] | Incremental AUROC (full-covars): 0.00039 PGS R2 (no covariates): 0.00096 R²: 0.05613 PGS AUROC (no covariates): 0.5334 [0.44427, 0.62254] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005209 | PGS001369 (GBE_HC1090) |
PSS004103| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE acute appendicitis | — | AUROC: 0.57413 [0.55138, 0.59688] | R²: 0.00617 Incremental AUROC (full-covars): 0.00987 PGS R2 (no covariates): 0.00332 PGS AUROC (no covariates): 0.55036 [0.52746, 0.57326] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005215 | PGS001536 (GBE_HC1188) |
PSS004173| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.63509 [0.52563, 0.74454] | R²: 0.01654 Incremental AUROC (full-covars): -0.00281 PGS R2 (no covariates): 0.0 PGS AUROC (no covariates): 0.51169 [0.39527, 0.62811] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005216 | PGS001536 (GBE_HC1188) |
PSS004174| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.82774 [0.75298, 0.90249] | R²: 0.08055 Incremental AUROC (full-covars): 0.01924 PGS R2 (no covariates): 0.00431 PGS AUROC (no covariates): 0.57823 [0.37976, 0.7767] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005217 | PGS001536 (GBE_HC1188) |
PSS004175| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.6991 [0.61917, 0.77902] | R²: 0.03993 Incremental AUROC (full-covars): 0.01341 PGS R2 (no covariates): 0.00254 PGS AUROC (no covariates): 0.55625 [0.47549, 0.63701] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005218 | PGS001536 (GBE_HC1188) |
PSS004176| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.64566 [0.58746, 0.70386] | R²: 0.02575 Incremental AUROC (full-covars): 0.0309 PGS R2 (no covariates): 0.01048 PGS AUROC (no covariates): 0.60302 [0.5391, 0.66694] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM005219 | PGS001536 (GBE_HC1188) |
PSS004177| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE vitiligo | — | AUROC: 0.63449 [0.58754, 0.68144] | R²: 0.01686 Incremental AUROC (full-covars): 0.08163 PGS R2 (no covariates): 0.01621 PGS AUROC (no covariates): 0.64193 [0.59907, 0.68478] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009289 | PGS001785 (1kgeur_gbmi_leaveUKBBout_AcApp_pst_eff_a1_b0.5_phiauto) |
PSS007708| European Ancestry| 359,031 individuals |
PGP000262 | Wang Y et al. Cell Genom (2023) |
Reported Trait: Acute appendicitis | — | AUROC: 0.584 | Nagelkerke's R2 (covariates regressed out): 0.00406 | sex,age,age2,age*sex,age^2*sex, 20PCs | — |
| PPM009420 | PGS001815 (portability-PLR_242) |
PSS009285| European Ancestry| 19,108 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0191 [0.0049, 0.0332] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009421 | PGS001815 (portability-PLR_242) |
PSS009059| European Ancestry| 3,938 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0288 [-0.0025, 0.06] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009422 | PGS001815 (portability-PLR_242) |
PSS008613| European Ancestry| 6,381 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0232 [-0.0014, 0.0477] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009423 | PGS001815 (portability-PLR_242) |
PSS008389| Greater Middle Eastern Ancestry| 1,143 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): -0.0026 [-0.0611, 0.0559] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009424 | PGS001815 (portability-PLR_242) |
PSS008167| South Asian Ancestry| 5,954 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0473 [0.0219, 0.0726] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009425 | PGS001815 (portability-PLR_242) |
PSS007954| East Asian Ancestry| 1,754 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0177 [-0.0294, 0.0647] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009426 | PGS001815 (portability-PLR_242) |
PSS007735| African Ancestry| 2,410 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): -0.0007 [-0.0408, 0.0394] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009427 | PGS001815 (portability-PLR_242) |
PSS008838| African Ancestry| 3,836 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0182 [-0.0135, 0.0499] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009541 | PGS001831 (portability-PLR_335) |
PSS009301| European Ancestry| 19,299 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0367 [0.0226, 0.0508] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009542 | PGS001831 (portability-PLR_335) |
PSS009075| European Ancestry| 4,011 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0122 [-0.0188, 0.0432] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009543 | PGS001831 (portability-PLR_335) |
PSS008629| European Ancestry| 6,463 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0578 [0.0334, 0.0821] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009544 | PGS001831 (portability-PLR_335) |
PSS008403| Greater Middle Eastern Ancestry| 1,164 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0242 [-0.0338, 0.082] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009545 | PGS001831 (portability-PLR_335) |
PSS008183| South Asian Ancestry| 6,094 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0064 [-0.0188, 0.0315] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009546 | PGS001831 (portability-PLR_335) |
PSS007749| African Ancestry| 2,390 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0032 [-0.037, 0.0435] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009547 | PGS001831 (portability-PLR_335) |
PSS008853| African Ancestry| 3,790 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): -0.0104 [-0.0423, 0.0216] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009730 | PGS001855 (portability-PLR_555.2) |
PSS009330| European Ancestry| 16,188 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0625 [0.0471, 0.0778] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009732 | PGS001855 (portability-PLR_555.2) |
PSS008658| European Ancestry| 5,477 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0453 [0.0188, 0.0717] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009733 | PGS001855 (portability-PLR_555.2) |
PSS008432| Greater Middle Eastern Ancestry| 1,007 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0175 [-0.0449, 0.0799] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009734 | PGS001855 (portability-PLR_555.2) |
PSS008212| South Asian Ancestry| 5,337 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0407 [0.0139, 0.0676] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009735 | PGS001855 (portability-PLR_555.2) |
PSS007994| East Asian Ancestry| 1,630 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0382 [-0.0107, 0.0868] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009736 | PGS001855 (portability-PLR_555.2) |
PSS007777| African Ancestry| 2,105 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.031 [-0.0119, 0.0738] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009737 | PGS001855 (portability-PLR_555.2) |
PSS008881| African Ancestry| 3,465 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): -0.0003 [-0.0337, 0.0331] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009731 | PGS001855 (portability-PLR_555.2) |
PSS009104| European Ancestry| 3,520 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0367 [0.0036, 0.0698] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009888 | PGS001875 (portability-PLR_714.1) |
PSS009352| European Ancestry| 18,393 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0416 [0.0272, 0.056] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009889 | PGS001875 (portability-PLR_714.1) |
PSS009126| European Ancestry| 3,878 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0554 [0.0239, 0.0868] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009890 | PGS001875 (portability-PLR_714.1) |
PSS008680| European Ancestry| 6,241 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0322 [0.0073, 0.057] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009891 | PGS001875 (portability-PLR_714.1) |
PSS008454| Greater Middle Eastern Ancestry| 1,128 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0363 [-0.0226, 0.095] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009892 | PGS001875 (portability-PLR_714.1) |
PSS008234| South Asian Ancestry| 5,728 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0097 [-0.0163, 0.0356] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009893 | PGS001875 (portability-PLR_714.1) |
PSS008014| East Asian Ancestry| 1,754 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0277 [-0.0194, 0.0746] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009894 | PGS001875 (portability-PLR_714.1) |
PSS007799| African Ancestry| 2,277 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): -0.0138 [-0.055, 0.0275] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009895 | PGS001875 (portability-PLR_714.1) |
PSS008903| African Ancestry| 3,634 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): -0.0251 [-0.0577, 0.0075] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009896 | PGS001876 (portability-PLR_715.2) |
PSS009353| European Ancestry| 18,262 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0797 [0.0653, 0.0941] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009897 | PGS001876 (portability-PLR_715.2) |
PSS009127| European Ancestry| 3,854 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0453 [0.0137, 0.0769] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009898 | PGS001876 (portability-PLR_715.2) |
PSS008681| European Ancestry| 6,216 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0521 [0.0272, 0.0769] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009899 | PGS001876 (portability-PLR_715.2) |
PSS008455| Greater Middle Eastern Ancestry| 1,124 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.1472 [0.0889, 0.2044] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009900 | PGS001876 (portability-PLR_715.2) |
PSS008235| South Asian Ancestry| 5,671 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0279 [0.0019, 0.054] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011058 | PGS002023 (portability-ldpred2_242) |
PSS009285| European Ancestry| 19,108 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0199 [0.0057, 0.034] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011059 | PGS002023 (portability-ldpred2_242) |
PSS009059| European Ancestry| 3,938 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0345 [0.0032, 0.0658] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011060 | PGS002023 (portability-ldpred2_242) |
PSS008613| European Ancestry| 6,381 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0195 [-0.0051, 0.044] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011061 | PGS002023 (portability-ldpred2_242) |
PSS008389| Greater Middle Eastern Ancestry| 1,143 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): -0.0281 [-0.0864, 0.0305] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011062 | PGS002023 (portability-ldpred2_242) |
PSS008167| South Asian Ancestry| 5,954 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0457 [0.0203, 0.0711] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011063 | PGS002023 (portability-ldpred2_242) |
PSS007954| East Asian Ancestry| 1,754 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.039 [-0.0081, 0.0859] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011064 | PGS002023 (portability-ldpred2_242) |
PSS007735| African Ancestry| 2,410 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0027 [-0.0374, 0.0428] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011065 | PGS002023 (portability-ldpred2_242) |
PSS008838| African Ancestry| 3,836 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Thyrotoxicosis with or without goiter | — | — | Partial Correlation (partial-r): 0.0172 [-0.0146, 0.0489] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011172 | PGS002038 (portability-ldpred2_335) |
PSS009075| European Ancestry| 4,011 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0083 [-0.0228, 0.0393] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011173 | PGS002038 (portability-ldpred2_335) |
PSS008629| European Ancestry| 6,463 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0447 [0.0203, 0.069] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011174 | PGS002038 (portability-ldpred2_335) |
PSS008403| Greater Middle Eastern Ancestry| 1,164 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0296 [-0.0284, 0.0874] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011175 | PGS002038 (portability-ldpred2_335) |
PSS008183| South Asian Ancestry| 6,094 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0149 [-0.0103, 0.04] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011176 | PGS002038 (portability-ldpred2_335) |
PSS007749| African Ancestry| 2,390 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.006 [-0.0343, 0.0463] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011177 | PGS002038 (portability-ldpred2_335) |
PSS008853| African Ancestry| 3,790 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): -0.0243 [-0.0561, 0.0077] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011171 | PGS002038 (portability-ldpred2_335) |
PSS009301| European Ancestry| 19,299 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Multiple sclerosis | — | — | Partial Correlation (partial-r): 0.0396 [0.0255, 0.0536] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011390 | PGS002066 (portability-ldpred2_555.2) |
PSS009330| European Ancestry| 16,188 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0641 [0.0487, 0.0794] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011391 | PGS002066 (portability-ldpred2_555.2) |
PSS009104| European Ancestry| 3,520 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0466 [0.0135, 0.0796] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011392 | PGS002066 (portability-ldpred2_555.2) |
PSS008658| European Ancestry| 5,477 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0426 [0.0161, 0.0691] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011393 | PGS002066 (portability-ldpred2_555.2) |
PSS008432| Greater Middle Eastern Ancestry| 1,007 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0056 [-0.0568, 0.068] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011395 | PGS002066 (portability-ldpred2_555.2) |
PSS007994| East Asian Ancestry| 1,630 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0398 [-0.009, 0.0885] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011396 | PGS002066 (portability-ldpred2_555.2) |
PSS007777| African Ancestry| 2,105 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0272 [-0.0157, 0.0701] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011397 | PGS002066 (portability-ldpred2_555.2) |
PSS008881| African Ancestry| 3,465 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0058 [-0.0276, 0.0392] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011394 | PGS002066 (portability-ldpred2_555.2) |
PSS008212| South Asian Ancestry| 5,337 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ulcerative colitis | — | — | Partial Correlation (partial-r): 0.0388 [0.0119, 0.0656] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011564 | PGS002088 (portability-ldpred2_714.1) |
PSS009352| European Ancestry| 18,393 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0434 [0.029, 0.0578] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011565 | PGS002088 (portability-ldpred2_714.1) |
PSS009126| European Ancestry| 3,878 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0532 [0.0217, 0.0846] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011566 | PGS002088 (portability-ldpred2_714.1) |
PSS008680| European Ancestry| 6,241 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0284 [0.0036, 0.0532] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011568 | PGS002088 (portability-ldpred2_714.1) |
PSS008234| South Asian Ancestry| 5,728 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0135 [-0.0125, 0.0394] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011569 | PGS002088 (portability-ldpred2_714.1) |
PSS008014| East Asian Ancestry| 1,754 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0226 [-0.0245, 0.0696] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011570 | PGS002088 (portability-ldpred2_714.1) |
PSS007799| African Ancestry| 2,277 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): -0.0007 [-0.0419, 0.0406] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011571 | PGS002088 (portability-ldpred2_714.1) |
PSS008903| African Ancestry| 3,634 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): -0.0214 [-0.054, 0.0112] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011567 | PGS002088 (portability-ldpred2_714.1) |
PSS008454| Greater Middle Eastern Ancestry| 1,128 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0403 [-0.0186, 0.099] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011572 | PGS002089 (portability-ldpred2_715.2) |
PSS009353| European Ancestry| 18,262 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0919 [0.0775, 0.1063] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011573 | PGS002089 (portability-ldpred2_715.2) |
PSS009127| European Ancestry| 3,854 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0476 [0.016, 0.0791] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011574 | PGS002089 (portability-ldpred2_715.2) |
PSS008681| European Ancestry| 6,216 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0596 [0.0348, 0.0844] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011576 | PGS002089 (portability-ldpred2_715.2) |
PSS008235| South Asian Ancestry| 5,671 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0424 [0.0163, 0.0684] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011575 | PGS002089 (portability-ldpred2_715.2) |
PSS008455| Greater Middle Eastern Ancestry| 1,124 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.1631 [0.1051, 0.22] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012870 | PGS002260 (PRS_RA) |
PSS009586| East Asian Ancestry| 740 individuals |
PGP000286 | Honda S et al. Arthritis Rheumatol (2022) |
Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis | — | — | OR (top vs 2nd quintile): 1.87 [1.11, 3.15] | — | — |
| PPM012871 | PGS002260 (PRS_RA) |
PSS009586| East Asian Ancestry| 740 individuals |
PGP000286 | Honda S et al. Arthritis Rheumatol (2022) |
Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis (age of onset <40 years) | — | — | OR (top vs 2nd quintile): 6.29 [1.85, 21.4] | — | — |
| PPM012872 | PGS002260 (PRS_RA) |
PSS009586| East Asian Ancestry| 740 individuals |
PGP000286 | Honda S et al. Arthritis Rheumatol (2022) |
Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis | OR: 1.3 [1.13, 1.5] | — | — | Age of onset, sex, ever-smoker, ACPAs positivity, rheumatoid factor positivity, BMI, periodontitis, use of methotrexate, use of bDMARD, HLA-DRB1 (Ser11) | — |
| PPM013077 | PGS002312 (disease_AID_ALL.BOLT-LMM) |
PSS009691| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0011 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013126 | PGS002312 (disease_AID_ALL.BOLT-LMM) |
PSS009692| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0015 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013175 | PGS002312 (disease_AID_ALL.BOLT-LMM) |
PSS009693| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0124 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013224 | PGS002312 (disease_AID_ALL.BOLT-LMM) |
PSS009694| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0073 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013271 | PGS002359 (disease_AID_ALL.BOLT-LMM-BBJ) |
PSS009691| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013294 | PGS002359 (disease_AID_ALL.BOLT-LMM-BBJ) |
PSS009692| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013317 | PGS002359 (disease_AID_ALL.BOLT-LMM-BBJ) |
PSS009693| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013340 | PGS002359 (disease_AID_ALL.BOLT-LMM-BBJ) |
PSS009694| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013365 | PGS002384 (disease_AID_ALL.P+T.0.0001) |
PSS009691| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013463 | PGS002384 (disease_AID_ALL.P+T.0.0001) |
PSS009693| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0013 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013512 | PGS002384 (disease_AID_ALL.P+T.0.0001) |
PSS009694| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013414 | PGS002384 (disease_AID_ALL.P+T.0.0001) |
PSS009692| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0016 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013561 | PGS002433 (disease_AID_ALL.P+T.0.001) |
PSS009691| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013610 | PGS002433 (disease_AID_ALL.P+T.0.001) |
PSS009692| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0009 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013708 | PGS002433 (disease_AID_ALL.P+T.0.001) |
PSS009694| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013659 | PGS002433 (disease_AID_ALL.P+T.0.001) |
PSS009693| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013757 | PGS002482 (disease_AID_ALL.P+T.0.01) |
PSS009691| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013806 | PGS002482 (disease_AID_ALL.P+T.0.01) |
PSS009692| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0008 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013904 | PGS002482 (disease_AID_ALL.P+T.0.01) |
PSS009694| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0002 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013855 | PGS002482 (disease_AID_ALL.P+T.0.01) |
PSS009693| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM013953 | PGS002531 (disease_AID_ALL.P+T.1e-06) |
PSS009691| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014002 | PGS002531 (disease_AID_ALL.P+T.1e-06) |
PSS009692| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0025 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014100 | PGS002531 (disease_AID_ALL.P+T.1e-06) |
PSS009694| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0025 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014051 | PGS002531 (disease_AID_ALL.P+T.1e-06) |
PSS009693| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0039 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014149 | PGS002580 (disease_AID_ALL.P+T.5e-08) |
PSS009691| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0005 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014247 | PGS002580 (disease_AID_ALL.P+T.5e-08) |
PSS009693| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0034 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014296 | PGS002580 (disease_AID_ALL.P+T.5e-08) |
PSS009694| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0017 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014198 | PGS002580 (disease_AID_ALL.P+T.5e-08) |
PSS009692| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0015 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014345 | PGS002629 (disease_AID_ALL.PolyFun-pred) |
PSS009691| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0011 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_AID_ALL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014394 | PGS002629 (disease_AID_ALL.PolyFun-pred) |
PSS009692| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0013 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_AID_ALL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014443 | PGS002629 (disease_AID_ALL.PolyFun-pred) |
PSS009693| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0126 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_AID_ALL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014492 | PGS002629 (disease_AID_ALL.PolyFun-pred) |
PSS009694| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0084 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See disease_AID_ALL.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
| PPM014541 | PGS002678 (disease_AID_ALL.SBayesR) |
PSS009691| African Ancestry| 6,503 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014590 | PGS002678 (disease_AID_ALL.SBayesR) |
PSS009692| East Asian Ancestry| 922 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0035 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014639 | PGS002678 (disease_AID_ALL.SBayesR) |
PSS009693| European Ancestry| 43,505 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0087 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014688 | PGS002678 (disease_AID_ALL.SBayesR) |
PSS009694| South Asian Ancestry| 8,098 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Autoimmune disease | — | — | Incremental R2 (full model vs. covariates alone): 0.0069 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
| PPM014749 | PGS002726 (PGS_MS_Brain) |
PSS009883| European Ancestry| 253,419 individuals |
PGP000334 | Shams H et al. Brain (2022) |
Reported Trait: Multiple sclerosis | — | AUROC: 0.73 [0.72, 0.74] | Odds ratio (OR, top 10% vs median): 5.3 [4.7, 6.0] | — | — |
| PPM014750 | PGS002726 (PGS_MS_Brain) |
PSS009882| European Ancestry| 938 individuals |
PGP000334 | Shams H et al. Brain (2022) |
Reported Trait: Multiple sclerosis | — | AUROC: 0.8 [0.76, 0.82] | Odds ratio (OR, top 10% vs median): 15.0 [10.4, 24.0] | — | — |
| PPM014915 | PGS002745 (metaPGS_RA) |
PSS009927| Multi-ancestry (including European)| 7,460 individuals |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.65 | Liability R2: 0.054 | Sex, Genotype PCs | Performance metrics are the mean values across eave-one-cohort-out cross-validation folds |
| PPM014916 | PGS002745 (metaPGS_RA) |
PSS009930| European Ancestry| 3,887 individuals |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.66 | Liability R2: 0.059 | Sex, Genotype PCs | Performance metrics are the mean values across eave-one-cohort-out cross-validation folds |
| PPM014917 | PGS002745 (metaPGS_RA) |
PSS009929| East Asian Ancestry| 21,704 individuals |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.66 | Liability R2: 0.057 | Sex, Genotype PCs | Performance metrics are the mean values across eave-one-cohort-out cross-validation folds |
| PPM014918 | PGS002745 (metaPGS_RA) |
PSS009928| Multi-ancestry (excluding European)| 1,304 individuals |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.59 | Liability R2: 0.018 | Sex, Genotype PCs | Performance metrics are the mean values across eave-one-cohort-out cross-validation folds |
| PPM014969 | PGS002769 (Rheumatoid_arthritis_prscs) |
PSS009939| European Ancestry| 39,444 individuals |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Reported Trait: Seropositive rheumatoid arthritis | OR: 1.72 [1.61, 1.83] | — | — | age, sex, 10 PCs, technical covariates | — |
| PPM017073 | PGS003420 (PRS100_PRScs) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7886 | — | — | — |
| PPM017074 | PGS003421 (PRS16_C+T) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7876 | — | — | — |
| PPM017075 | PGS003422 (PRS16_PRSice2) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7876 | — | — | — |
| PPM017076 | PGS003423 (PRS100_Lassosum) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7754 | — | — | — |
| PPM017077 | PGS003424 (PRS100_LDpred2) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7605 | — | — | — |
| PPM018525 | PGS003755 (wGRS_SLE) |
PSS011006| East Asian Ancestry| 1,655 individuals |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Reported Trait: Class III/IV lupus nephritis in anti-sm positive systemic lupus erythematosus | — | AUROC: 0.582 [0.496, 0.668] | — | — | — |
| PPM018519 | PGS003755 (wGRS_SLE) |
PSS011006| East Asian Ancestry| 1,655 individuals |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Reported Trait: Childhood-onset systemic lupus erythematosus (onset at age <16 years) | — | — | p: 6.80e-08 | — | — |
| PPM018520 | PGS003755 (wGRS_SLE) |
PSS011006| East Asian Ancestry| 1,655 individuals |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Reported Trait: Number of American College of Rheumatology (ACR) criteria for systemic lupus erythematosus | β: 0.143 [0.078, 0.208] | — | — | Onset age, sex, disease duration, and top 4 principal components | — |
| PPM018523 | PGS003755 (wGRS_SLE) |
PSS011006| East Asian Ancestry| 1,655 individuals |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Reported Trait: Renal disorder | β: 1.22 [1.12, 1.33] | — | — | Onset age, sex, disease duration, and top 4 principal components | — |
| PPM018524 | PGS003755 (wGRS_SLE) |
PSS011006| East Asian Ancestry| 1,655 individuals |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Reported Trait: Production of anti-Sm antibody | β: 1.23 [1.11, 1.36] | — | — | Onset age, sex, disease duration, and top 4 principal components | — |
| PPM018526 | PGS003755 (wGRS_SLE) |
PSS011006| East Asian Ancestry| 1,655 individuals |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Reported Trait: Class V lupus nephritis in anti-sm positive systemic lupus erythematosus | — | AUROC: 0.681 [0.602, 0.76] | — | — | — |
| PPM018521 | PGS003756 (wGRS_SLE_non-HLA) |
PSS011006| East Asian Ancestry| 1,655 individuals |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Reported Trait: Number of American College of Rheumatology (ACR) criteria for systemic lupus erythematosus | β: 0.133 [0.071, 0.194] | — | — | Onset age, sex, disease duration, and top 4 principal components | — |
| PPM018522 | PGS003757 (wGRS_SLE_HLA) |
PSS011006| East Asian Ancestry| 1,655 individuals |
PGP000475 | Kwon YC et al. Arthritis Rheumatol (2023) |
Reported Trait: Number of American College of Rheumatology (ACR) criteria for systemic lupus erythematosus | β: 0.213 [0.079, 0.347] | — | — | Onset age, sex, disease duration, and top 4 principal components | — |
| PPM019115 | PGS003960 (GRS57_SLE) |
PSS011186| Multi-ancestry (including European)| 3,048 individuals |
PGP000509 | Barnado A et al. Arthritis Rheumatol (2023) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.65 [0.63, 0.67] | — | — | — |
| PPM019116 | PGS003960 (GRS57_SLE) |
PSS011188| European Ancestry| 1,994 individuals |
PGP000509 | Barnado A et al. Arthritis Rheumatol (2023) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.63 [0.6, 0.66] | — | — | — |
| PPM019117 | PGS003960 (GRS57_SLE) |
PSS011187| African Ancestry| 902 individuals |
PGP000509 | Barnado A et al. Arthritis Rheumatol (2023) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.5 [0.44, 0.56] | — | — | — |
| PPM019118 | PGS003960 (GRS57_SLE) |
PSS011186| Multi-ancestry (including European)| 3,048 individuals |
PGP000509 | Barnado A et al. Arthritis Rheumatol (2023) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.89 [0.87, 0.9] | — | phenotype risk score | — |
| PPM019119 | PGS003960 (GRS57_SLE) |
PSS011188| European Ancestry| 1,994 individuals |
PGP000509 | Barnado A et al. Arthritis Rheumatol (2023) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.87 [0.85, 0.89] | — | phenotype risk score | — |
| PPM019120 | PGS003960 (GRS57_SLE) |
PSS011187| African Ancestry| 902 individuals |
PGP000509 | Barnado A et al. Arthritis Rheumatol (2023) |
Reported Trait: Systemic lupus erythematosus | — | AUROC: 0.89 [0.86, 0.93] | — | phenotype risk score | — |
| PPM019233 | PGS003981 (dbslmm.auto.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.33244 β: 0.28701 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019234 | PGS003981 (dbslmm.auto.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.89729 β: 0.64043 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM019235 | PGS003981 (dbslmm.auto.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.82983 β: 0.60422 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019236 | PGS003981 (dbslmm.auto.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.51174 β: 0.41326 |
AUROC: 0.61 | — | 0 | beta = log(or)/sd_pgs |
| PPM019237 | PGS003981 (dbslmm.auto.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.62008 β: 0.48247 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM019238 | PGS003981 (dbslmm.auto.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.8704 β: 0.62615 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM020015 | PGS003994 (dbslmm.auto.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.33393 β: 0.28813 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM020017 | PGS003994 (dbslmm.auto.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.37351 β: 0.31737 |
AUROC: 0.57 | — | 0 | beta = log(or)/sd_pgs |
| PPM020018 | PGS003994 (dbslmm.auto.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.1176 β: 0.11118 |
AUROC: 0.53 | — | 0 | beta = log(or)/sd_pgs |
| PPM020019 | PGS003994 (dbslmm.auto.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.82399 β: 0.60103 |
AUROC: 0.66 | — | 0 | beta = log(or)/sd_pgs |
| PPM020016 | PGS003994 (dbslmm.auto.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.50841 β: 0.41106 |
AUROC: 0.61 | — | 0 | beta = log(or)/sd_pgs |
| PPM019287 | PGS003997 (lassosum.auto.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.35075 β: 0.30066 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019288 | PGS003997 (lassosum.auto.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.94603 β: 0.66579 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019289 | PGS003997 (lassosum.auto.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.83801 β: 0.60869 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM019290 | PGS003997 (lassosum.auto.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.53922 β: 0.43128 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019291 | PGS003997 (lassosum.auto.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.73594 β: 0.55155 |
AUROC: 0.65 | — | 0 | beta = log(or)/sd_pgs |
| PPM019292 | PGS003997 (lassosum.auto.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.84612 β: 0.61309 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM020050 | PGS004010 (lassosum.auto.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.32987 β: 0.28508 |
AUROC: 0.59 | — | 0 | beta = log(or)/sd_pgs |
| PPM020051 | PGS004010 (lassosum.auto.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.49732 β: 0.40368 |
AUROC: 0.61 | — | 0 | beta = log(or)/sd_pgs |
| PPM020052 | PGS004010 (lassosum.auto.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.28607 β: 0.25159 |
AUROC: 0.6 | — | 0 | beta = log(or)/sd_pgs |
| PPM020053 | PGS004010 (lassosum.auto.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.18691 β: 0.17135 |
AUROC: 0.56 | — | 0 | beta = log(or)/sd_pgs |
| PPM020054 | PGS004010 (lassosum.auto.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.59047 β: 0.46403 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM019281 | PGS004013 (lassosum.CV.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.37266 β: 0.31675 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019282 | PGS004013 (lassosum.CV.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.95504 β: 0.67041 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019283 | PGS004013 (lassosum.CV.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.88804 β: 0.63554 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019284 | PGS004013 (lassosum.CV.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.53614 β: 0.42927 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019285 | PGS004013 (lassosum.CV.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.72939 β: 0.54777 |
AUROC: 0.65 | — | 0 | beta = log(or)/sd_pgs |
| PPM019286 | PGS004013 (lassosum.CV.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.8643 β: 0.62289 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM020055 | PGS004021 (lassosum.CV.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.46364 β: 0.38093 |
AUROC: 0.6 | — | 0 | beta = log(or)/sd_pgs |
| PPM020056 | PGS004021 (lassosum.CV.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.61006 β: 0.47627 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM020057 | PGS004021 (lassosum.CV.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.91213 β: 0.64822 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM020058 | PGS004021 (lassosum.CV.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.4387 β: 0.36374 |
AUROC: 0.6 | — | 0 | beta = log(or)/sd_pgs |
| PPM020059 | PGS004021 (lassosum.CV.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 2.11267 β: 0.74795 |
AUROC: 0.71 | — | 0 | beta = log(or)/sd_pgs |
| PPM019252 | PGS004023 (ldpred2.auto.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.98269 β: 0.68445 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019253 | PGS004023 (ldpred2.auto.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.96487 β: 0.67543 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM019254 | PGS004023 (ldpred2.auto.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.53961 β: 0.43153 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019255 | PGS004023 (ldpred2.auto.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.7204 β: 0.54256 |
AUROC: 0.64 | — | 0 | beta = log(or)/sd_pgs |
| PPM019256 | PGS004023 (ldpred2.auto.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.95616 β: 0.67098 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019251 | PGS004023 (ldpred2.auto.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.37223 β: 0.31644 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019215 | PGS004038 (ldpred2.CV.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.3661 β: 0.31196 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019216 | PGS004038 (ldpred2.CV.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 2.00709 β: 0.69669 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM019217 | PGS004038 (ldpred2.CV.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.946 β: 0.66578 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM019218 | PGS004038 (ldpred2.CV.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.55477 β: 0.44133 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019219 | PGS004038 (ldpred2.CV.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.71999 β: 0.54232 |
AUROC: 0.64 | — | 0 | beta = log(or)/sd_pgs |
| PPM019220 | PGS004038 (ldpred2.CV.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.96885 β: 0.67745 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM020001 | PGS004049 (ldpred2.CV.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.63972 β: 0.49453 |
AUROC: 0.64 | — | 0 | beta = log(or)/sd_pgs |
| PPM020002 | PGS004049 (ldpred2.CV.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.9896 β: 0.68793 |
AUROC: 0.71 | — | 0 | beta = log(or)/sd_pgs |
| PPM020003 | PGS004049 (ldpred2.CV.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.54092 β: 0.43238 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM020004 | PGS004049 (ldpred2.CV.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 2.36914 β: 0.86253 |
AUROC: 0.73 | — | 0 | beta = log(or)/sd_pgs |
| PPM020000 | PGS004049 (ldpred2.CV.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.55377 β: 0.44069 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019257 | PGS004051 (megaprs.auto.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.36888 β: 0.314 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019258 | PGS004051 (megaprs.auto.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 2.00653 β: 0.69641 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM019259 | PGS004051 (megaprs.auto.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.90388 β: 0.64389 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019260 | PGS004051 (megaprs.auto.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.53763 β: 0.43024 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019261 | PGS004051 (megaprs.auto.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.63845 β: 0.49375 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM019262 | PGS004051 (megaprs.auto.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.9624 β: 0.67417 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM020035 | PGS004064 (megaprs.auto.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.52285 β: 0.42059 |
AUROC: 0.61 | — | 0 | beta = log(or)/sd_pgs |
| PPM020036 | PGS004064 (megaprs.auto.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.6765 β: 0.51671 |
AUROC: 0.64 | — | 0 | beta = log(or)/sd_pgs |
| PPM020037 | PGS004064 (megaprs.auto.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 2.16519 β: 0.77251 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM020038 | PGS004064 (megaprs.auto.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.52777 β: 0.42381 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM020039 | PGS004064 (megaprs.auto.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 2.12896 β: 0.75563 |
AUROC: 0.71 | — | 0 | beta = log(or)/sd_pgs |
| PPM019263 | PGS004067 (megaprs.CV.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.38476 β: 0.32553 |
AUROC: 0.59 | — | 0 | beta = log(or)/sd_pgs |
| PPM019264 | PGS004067 (megaprs.CV.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 2.01137 β: 0.69881 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM019265 | PGS004067 (megaprs.CV.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.90373 β: 0.64382 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019266 | PGS004067 (megaprs.CV.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.53272 β: 0.42704 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019267 | PGS004067 (megaprs.CV.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.64423 β: 0.49727 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM019268 | PGS004067 (megaprs.CV.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.9918 β: 0.68904 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM020030 | PGS004079 (megaprs.CV.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.50199 β: 0.40679 |
AUROC: 0.61 | — | 0 | beta = log(or)/sd_pgs |
| PPM020031 | PGS004079 (megaprs.CV.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.61696 β: 0.48055 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM020032 | PGS004079 (megaprs.CV.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 2.0218 β: 0.70399 |
AUROC: 0.71 | — | 0 | beta = log(or)/sd_pgs |
| PPM020033 | PGS004079 (megaprs.CV.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.60515 β: 0.47322 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM020034 | PGS004079 (megaprs.CV.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 2.22137 β: 0.79813 |
AUROC: 0.72 | — | 0 | beta = log(or)/sd_pgs |
| PPM019275 | PGS004081 (prscs.auto.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.33947 β: 0.29227 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019276 | PGS004081 (prscs.auto.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.93798 β: 0.66165 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019277 | PGS004081 (prscs.auto.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.81701 β: 0.59719 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM019278 | PGS004081 (prscs.auto.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.52897 β: 0.4246 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019279 | PGS004081 (prscs.auto.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.64491 β: 0.49768 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM019280 | PGS004081 (prscs.auto.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.87137 β: 0.62667 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM020045 | PGS004094 (prscs.auto.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.43309 β: 0.35983 |
AUROC: 0.6 | — | 0 | beta = log(or)/sd_pgs |
| PPM020046 | PGS004094 (prscs.auto.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.64768 β: 0.49937 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM020047 | PGS004094 (prscs.auto.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.45841 β: 0.37734 |
AUROC: 0.61 | — | 0 | beta = log(or)/sd_pgs |
| PPM020048 | PGS004094 (prscs.auto.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.30074 β: 0.26293 |
AUROC: 0.59 | — | 0 | beta = log(or)/sd_pgs |
| PPM020049 | PGS004094 (prscs.auto.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.88898 β: 0.63604 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM019269 | PGS004097 (prscs.CV.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.33762 β: 0.29089 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019270 | PGS004097 (prscs.CV.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.9368 β: 0.66104 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019271 | PGS004097 (prscs.CV.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.81277 β: 0.59485 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM019272 | PGS004097 (prscs.CV.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.53892 β: 0.43108 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019273 | PGS004097 (prscs.CV.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.64559 β: 0.4981 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM019274 | PGS004097 (prscs.CV.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.86814 β: 0.62494 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM020040 | PGS004103 (prscs.CV.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.39977 β: 0.33631 |
AUROC: 0.59 | — | 0 | beta = log(or)/sd_pgs |
| PPM020041 | PGS004103 (prscs.CV.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.43354 β: 0.36015 |
AUROC: 0.6 | — | 0 | beta = log(or)/sd_pgs |
| PPM020042 | PGS004103 (prscs.CV.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.62378 β: 0.48476 |
AUROC: 0.65 | — | 0 | beta = log(or)/sd_pgs |
| PPM020043 | PGS004103 (prscs.CV.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.24983 β: 0.22301 |
AUROC: 0.56 | — | 0 | beta = log(or)/sd_pgs |
| PPM020044 | PGS004103 (prscs.CV.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.9189 β: 0.65175 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019221 | PGS004105 (pt_clump.auto.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.24143 β: 0.21627 |
AUROC: 0.56 | — | 0 | beta = log(or)/sd_pgs |
| PPM019222 | PGS004105 (pt_clump.auto.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.63002 β: 0.48859 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM019223 | PGS004105 (pt_clump.auto.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.40101 β: 0.33719 |
AUROC: 0.6 | — | 0 | beta = log(or)/sd_pgs |
| PPM019224 | PGS004105 (pt_clump.auto.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.35946 β: 0.30709 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019225 | PGS004105 (pt_clump.auto.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.34635 β: 0.29739 |
AUROC: 0.59 | — | 0 | beta = log(or)/sd_pgs |
| PPM019226 | PGS004105 (pt_clump.auto.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.59062 β: 0.46412 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM020005 | PGS004118 (pt_clump.auto.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.33056 β: 0.2856 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM020006 | PGS004118 (pt_clump.auto.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.40296 β: 0.33858 |
AUROC: 0.59 | — | 0 | beta = log(or)/sd_pgs |
| PPM020007 | PGS004118 (pt_clump.auto.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.70576 β: 0.53401 |
AUROC: 0.65 | — | 0 | beta = log(or)/sd_pgs |
| PPM020008 | PGS004118 (pt_clump.auto.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.30274 β: 0.26447 |
AUROC: 0.57 | — | 0 | beta = log(or)/sd_pgs |
| PPM020009 | PGS004118 (pt_clump.auto.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.56663 β: 0.44893 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019227 | PGS004121 (pt_clump_nested.CV.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.27323 β: 0.24156 |
AUROC: 0.56 | — | 0 | beta = log(or)/sd_pgs |
| PPM019228 | PGS004121 (pt_clump_nested.CV.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.74769 β: 0.55829 |
AUROC: 0.65 | — | 0 | beta = log(or)/sd_pgs |
| PPM019229 | PGS004121 (pt_clump_nested.CV.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.51461 β: 0.41516 |
AUROC: 0.61 | — | 0 | beta = log(or)/sd_pgs |
| PPM019230 | PGS004121 (pt_clump_nested.CV.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.38976 β: 0.32913 |
AUROC: 0.59 | — | 0 | beta = log(or)/sd_pgs |
| PPM019231 | PGS004121 (pt_clump_nested.CV.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.49325 β: 0.40096 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019232 | PGS004121 (pt_clump_nested.CV.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.68525 β: 0.52191 |
AUROC: 0.65 | — | 0 | beta = log(or)/sd_pgs |
| PPM020010 | PGS004133 (pt_clump_nested.CV.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.34749 β: 0.29824 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM020011 | PGS004133 (pt_clump_nested.CV.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.43562 β: 0.3616 |
AUROC: 0.6 | — | 0 | beta = log(or)/sd_pgs |
| PPM020012 | PGS004133 (pt_clump_nested.CV.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.54617 β: 0.43578 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM020013 | PGS004133 (pt_clump_nested.CV.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.33067 β: 0.28568 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM020014 | PGS004133 (pt_clump_nested.CV.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.49068 β: 0.39923 |
AUROC: 0.61 | — | 0 | beta = log(or)/sd_pgs |
| PPM019245 | PGS004135 (sbayesr.auto.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.33765 β: 0.29091 |
AUROC: 0.58 | — | 0 | beta = log(or)/sd_pgs |
| PPM019247 | PGS004135 (sbayesr.auto.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.8584 β: 0.61972 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM019248 | PGS004135 (sbayesr.auto.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.53371 β: 0.42769 |
AUROC: 0.61 | — | 0 | beta = log(or)/sd_pgs |
| PPM019249 | PGS004135 (sbayesr.auto.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.68556 β: 0.5221 |
AUROC: 0.65 | — | 0 | beta = log(or)/sd_pgs |
| PPM019250 | PGS004135 (sbayesr.auto.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.91118 β: 0.64772 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM019246 | PGS004135 (sbayesr.auto.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.982 β: 0.68411 |
AUROC: 0.68 | — | 0 | beta = log(or)/sd_pgs |
| PPM020020 | PGS004148 (sbayesr.auto.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.39911 β: 0.33583 |
AUROC: 0.59 | — | 0 | beta = log(or)/sd_pgs |
| PPM020021 | PGS004148 (sbayesr.auto.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.62873 β: 0.4878 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM020022 | PGS004148 (sbayesr.auto.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.86907 β: 0.62544 |
AUROC: 0.67 | — | 0 | beta = log(or)/sd_pgs |
| PPM020023 | PGS004148 (sbayesr.auto.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.46527 β: 0.38204 |
AUROC: 0.6 | — | 0 | beta = log(or)/sd_pgs |
| PPM020024 | PGS004148 (sbayesr.auto.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.74045 β: 0.55414 |
AUROC: 0.66 | — | 0 | beta = log(or)/sd_pgs |
| PPM019239 | PGS004151 (UKBB_EnsPGS.GCST004131.IBD) |
PSS011220| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.39728 β: 0.33453 |
AUROC: 0.59 | — | 0 | beta = log(or)/sd_pgs |
| PPM019240 | PGS004151 (UKBB_EnsPGS.GCST004131.IBD) |
PSS011231| European Ancestry| 396,819 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 2.06398 β: 0.72464 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM019241 | PGS004151 (UKBB_EnsPGS.GCST004131.IBD) |
PSS011244| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.99477 β: 0.69053 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM019242 | PGS004151 (UKBB_EnsPGS.GCST004131.IBD) |
PSS011260| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.58122 β: 0.4582 |
AUROC: 0.62 | — | 0 | beta = log(or)/sd_pgs |
| PPM019243 | PGS004151 (UKBB_EnsPGS.GCST004131.IBD) |
PSS011288| South Asian Ancestry| 9,326 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 1.76291 β: 0.56697 |
AUROC: 0.65 | — | 0 | beta = log(or)/sd_pgs |
| PPM019244 | PGS004151 (UKBB_EnsPGS.GCST004131.IBD) |
PSS011273| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Inflammatory bowel disease | OR: 2.04212 β: 0.71399 |
AUROC: 0.69 | — | 0 | beta = log(or)/sd_pgs |
| PPM020025 | PGS004163 (UKBB_EnsPGS.GCST90013534.RA) |
PSS011222| European Ancestry| 199,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.64114 β: 0.49539 |
AUROC: 0.63 | — | 0 | beta = log(or)/sd_pgs |
| PPM020026 | PGS004163 (UKBB_EnsPGS.GCST90013534.RA) |
PSS011233| European Ancestry| 388,890 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.75402 β: 0.56191 |
AUROC: 0.65 | — | 0 | beta = log(or)/sd_pgs |
| PPM020027 | PGS004163 (UKBB_EnsPGS.GCST90013534.RA) |
PSS011246| South Asian Ancestry| 44,057 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 2.39078 β: 0.87162 |
AUROC: 0.74 | — | 0 | beta = log(or)/sd_pgs |
| PPM020028 | PGS004163 (UKBB_EnsPGS.GCST90013534.RA) |
PSS011262| European Ancestry| 66,865 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 1.6676 β: 0.51138 |
AUROC: 0.64 | — | 0 | beta = log(or)/sd_pgs |
| PPM020029 | PGS004163 (UKBB_EnsPGS.GCST90013534.RA) |
PSS011275| European Ancestry| 90,274 individuals |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Reported Trait: Seropositive RA | OR: 2.46183 β: 0.90091 |
AUROC: 0.75 | — | 0 | beta = log(or)/sd_pgs |
| PPM020320 | PGS004253 (uc_ldpred2) |
PSS011334| European Ancestry| 21,335 individuals |
PGP000545 | Middha P et al. Nat Commun (2024) |
Reported Trait: Ulcerative colitis | OR: 1.75 [1.59, 1.92] | AUROC: 0.65 [0.62, 0.68] | — | age, sex, 10 PCs | — |
| PPM020319 | PGS004253 (uc_ldpred2) |
PSS011335| European Ancestry| 5,735 individuals |
PGP000545 | Middha P et al. Nat Commun (2024) |
Reported Trait: Ulcerative colitis | OR: 1.84 [1.76, 1.93] | AUROC: 0.66 [0.64, 0.68] | — | age at diagnosis/enrollment, sex, genotyping array, 10 PCs | — |
| PPM020321 | PGS004254 (cd_ldpred2) |
PSS011333| European Ancestry| 5,285 individuals |
PGP000545 | Middha P et al. Nat Commun (2024) |
Reported Trait: Crohn's disease | OR: 1.83 [1.72, 1.95] | AUROC: 0.72 [0.69, 0.74] | — | age at diagnosis/enrollment, sex, genotyping array, 10 PCs | — |
| PPM020322 | PGS004254 (cd_ldpred2) |
PSS011332| European Ancestry| 22,296 individuals |
PGP000545 | Middha P et al. Nat Commun (2024) |
Reported Trait: Crohn's disease | OR: 2.18 [2.05, 2.32] | AUROC: 0.72 [0.7, 0.73] | — | age, sex, 10 PCs | — |
| PPM020323 | PGS004255 (GenoBoost_rheumatoid_arthritis_0) |
PSS011342| European Ancestry| 67,428 indiv |