Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000853
(T2D_Insulin_Secretion_2)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000853/ScoringFiles/PGS000853.txt.gz
PGS000852
(T2D_Insulin_Secretion_1)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz
PGS000851
(T2D_Insulin_Action_Secretion)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action/secretion) type 2 diabetes mellitus 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000851/ScoringFiles/PGS000851.txt.gz
PGS000850
(T2D_Insulin_Action)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with insulin action) type 2 diabetes mellitus 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000850/ScoringFiles/PGS000850.txt.gz
PGS000849
(T2D_Impaired_Lipids)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with impaired lipids) type 2 diabetes mellitus 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000849/ScoringFiles/PGS000849.txt.gz
PGS000848
(T2D_Adiposity)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (based on SNPs associated with adiposity) type 2 diabetes mellitus 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000848/ScoringFiles/PGS000848.txt.gz
PGS000847
(TG)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Triglycerides (TG) triglyceride measurement 201
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000847/ScoringFiles/PGS000847.txt.gz
PGS000846
(LDL)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 LDL cholesterol low density lipoprotein cholesterol measurement 275
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000846/ScoringFiles/PGS000846.txt.gz
PGS000845
(HDL)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 HDL cholesterol high density lipoprotein cholesterol measurement 303
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000845/ScoringFiles/PGS000845.txt.gz
PGS000844
(VAT_Mass)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Predicted visceral adipose tissue visceral adipose tissue measurement 518
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000844/ScoringFiles/PGS000844.txt.gz
PGS000843
(WHRadjBMI)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 WHR adjusted for BMI BMI-adjusted waist-hip ratio 63
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000843/ScoringFiles/PGS000843.txt.gz
PGS000842
(WHR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Waist-hip ratio waist-hip ratio 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000842/ScoringFiles/PGS000842.txt.gz
PGS000841
(BMI)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Body mass index (BMI) body mass index 122
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000841/ScoringFiles/PGS000841.txt.gz
PGS000840
(Fasting_Proinsulin)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Fasting Proinsulin proinsulin measurement 223
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000840/ScoringFiles/PGS000840.txt.gz
PGS000839
(2H_Glucose)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Two hour glucose during OGTT glucose tolerance test 219
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000839/ScoringFiles/PGS000839.txt.gz
PGS000838
(Fasting_Glucose)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Fasting glucose fasting blood glucose measurement 224
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000838/ScoringFiles/PGS000838.txt.gz
PGS000837
(ISI)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Insulin sensitivity index insulin sensitivity measurement 219
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000837/ScoringFiles/PGS000837.txt.gz
PGS000836
(F-INS)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Fasting insulin fasting blood insulin measurement 223
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000836/ScoringFiles/PGS000836.txt.gz
PGS000835
(ISR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Insulin secretion rate insulin secretion measurement 319
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000835/ScoringFiles/PGS000835.txt.gz
PGS000834
(CIR)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Corrected insulin response (at 30mins during OGTT) insulin response measurement 220
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000834/ScoringFiles/PGS000834.txt.gz
PGS000833
(T1D)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 66
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000833/ScoringFiles/PGS000833.txt.gz
PGS000832
(T2D-GRS)
 PGP000211 |
Aly DM et al. Nat Genet (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 384
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000832/ScoringFiles/PGS000832.txt.gz
PGS000831
(Total_cholesterol_PGS)
 PGP000210 |
Zubair N et al. Sci Rep (2019)
 Total cholesterol total cholesterol measurement 1,032
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000831/ScoringFiles/PGS000831.txt.gz - Check Terms/Licenses
PGS000830
(BMI_PGS_F)
 PGP000210 |
Zubair N et al. Sci Rep (2019)
 Body mass index (BMI) (female) body mass index,
female		 372
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000830/ScoringFiles/PGS000830.txt.gz - Check Terms/Licenses
PGS000829
(BMI_PGS_M)
 PGP000210 |
Zubair N et al. Sci Rep (2019)
 Body mass index (BMI) (male) body mass index,
male		 290
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000829/ScoringFiles/PGS000829.txt.gz - Check Terms/Licenses
PGS000828
(WaistCircumference_PGS_F)
 PGP000210 |
Zubair N et al. Sci Rep (2019)
 Waist circumference (female) waist circumference,
female		 149
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000828/ScoringFiles/PGS000828.txt.gz - Check Terms/Licenses
PGS000827
(WaistCircumference_PGS_M)
 PGP000210 |
Zubair N et al. Sci Rep (2019)
 Waist circumference (male) waist circumference,
male		 113
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000827/ScoringFiles/PGS000827.txt.gz - Check Terms/Licenses
PGS000826
(Triglycerides_PGS)
 PGP000210 |
Zubair N et al. Sci Rep (2019)
 Triglycerides triglyceride measurement 769
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000826/ScoringFiles/PGS000826.txt.gz - Check Terms/Licenses
PGS000825
(HDL-C_PGS)
 PGP000210 |
Zubair N et al. Sci Rep (2019)
 HDL cholesterol high density lipoprotein cholesterol measurement 883
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000825/ScoringFiles/PGS000825.txt.gz - Check Terms/Licenses
PGS000824
(LDL-C_PGS)
 PGP000210 |
Zubair N et al. Sci Rep (2019)
 LDL cholesterol low density lipoprotein cholesterol measurement 809
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000824/ScoringFiles/PGS000824.txt.gz - Check Terms/Licenses
PGS000823
(GRS23_AD)
 PGP000207 |
van der Lee SJ et al. Lancet Neurol (2018)
 Alzheimer's disease Alzheimer disease 23
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000823/ScoringFiles/PGS000823.txt.gz
PGS000822
(GRS_UACR)
 PGP000206 |
Teumer A et al. Nat Commun (2019)
 Urinary albumin to creatinine ratio urinary albumin to creatinine ratio 59
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000822/ScoringFiles/PGS000822.txt.gz
PGS000821
(PRS_hypomed)
 PGP000204 |
Luo J et al. Clin Cancer Res (2021)
 Thyroid medication use Thyroid preparation use measurement 872,391
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000821/ScoringFiles/PGS000821.txt.gz
PGS000820
(PRS_hypothyroidism)
 PGP000204 |
Luo J et al. Clin Cancer Res (2021)
 Hypothyroidism (self-reported) hypothyroidism 890,908
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000820/ScoringFiles/PGS000820.txt.gz
PGS000819
(PRS_DR)
 PGP000203 |
Forrest IS et al. Hum Mol Genet (2021)
 Diabetic retinopathy diabetic retinopathy 3,537,914
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000819/ScoringFiles/PGS000819.txt.gz
PGS000818
(GRS_Metabo)
 PGP000202 |
Bauer A et al. Genet Epidemiol (2021)
 Coronary heart disease coronary artery disease 138
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000818/ScoringFiles/PGS000818.txt.gz
PGS000817
(GRS200_GGT)
 PGP000201 |
Pazoki R et al. Nat Commun (2021)
 Gamma-glutamyl transferase serum gamma-glutamyl transferase measurement 200
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000817/ScoringFiles/PGS000817.txt.gz
PGS000816
(GRS150_ALT)
 PGP000201 |
Pazoki R et al. Nat Commun (2021)
 Alanine transaminase serum alanine aminotransferase measurement 150
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000816/ScoringFiles/PGS000816.txt.gz
PGS000815
(GRS290_ALP)
 PGP000201 |
Pazoki R et al. Nat Commun (2021)
 Alkaline phosphatase alkaline phosphatase measurement 290
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000815/ScoringFiles/PGS000815.txt.gz
PGS000814
(GRS12_LDLc)
 PGP000200 |
Talmud PJ et al. Lancet (2013)
 LDL cholesterol low density lipoprotein cholesterol measurement 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000814/ScoringFiles/PGS000814.txt.gz
PGS000813
(PRS46_melanoma)
 PGP000197 |
Potjer TP et al. J Med Genet (2020)
 Melanoma melanoma 46
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000813/ScoringFiles/PGS000813.txt.gz
PGS000812
(AD-PRS_57)
 PGP000196 |
Najar J et al. Alzheimers Dement (Amst) (2021)
 Alzheimer's disease Alzheimer disease 57
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000812/ScoringFiles/PGS000812.txt.gz
PGS000811
(AD-PRS_39)
 PGP000196 |
Najar J et al. Alzheimers Dement (Amst) (2021)
 Alzheimer's disease Alzheimer disease 39
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000811/ScoringFiles/PGS000811.txt.gz
PGS000810
(wGRS136_Allergy)
 PGP000195 |
Ferreira MA et al. Nat Genet (2017)
 Allergic disease (asthma, hay fever or eczema) allergic disease 136
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000810/ScoringFiles/PGS000810.txt.gz
PGS000809
(PRS127_MS)
 PGP000194 |
Barnes CLK et al. Eur J Hum Genet (2021)
 Multiple sclerosis multiple sclerosis 127
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000809/ScoringFiles/PGS000809.txt.gz
PGS000808
(GRS582_T2Dhis)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000808/ScoringFiles/PGS000808.txt.gz - Check Terms/Licenses
PGS000807
(GRS582_T2Dasn)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000807/ScoringFiles/PGS000807.txt.gz - Check Terms/Licenses
PGS000806
(GRS582_T2Dafr)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000806/ScoringFiles/PGS000806.txt.gz - Check Terms/Licenses
PGS000805
(GRS582_T2Deur)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000805/ScoringFiles/PGS000805.txt.gz - Check Terms/Licenses
PGS000804
(GRS582_T2Dmulti)
 PGP000193 |
Polfus LM et al. HGG Adv (2021)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 582
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000804/ScoringFiles/PGS000804.txt.gz - Check Terms/Licenses
Showing 4151 to 4200 of 5001 rows