Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS002097
(portability-ldpred2_960.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Allergy/adverse effect of penicillin drug allergy 742,904
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002097/ScoringFiles/PGS002097.txt.gz
PGS004253
(uc_ldpred2)
 PGP000545 |
Middha P et al. Nat Commun (2024)
 Ulcerative colitis ulcerative colitis 744,575
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004253/ScoringFiles/PGS004253.txt.gz
PGS004254
(cd_ldpred2)
 PGP000545 |
Middha P et al. Nat Commun (2024)
 Crohn's disease Crohn disease 744,682
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004254/ScoringFiles/PGS004254.txt.gz
PGS002069
(portability-ldpred2_564)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Functional digestive disorders digestive system disorder 747,820
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002069/ScoringFiles/PGS002069.txt.gz
PGS002112
(portability-ldpred2_depression_feelings)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Recent feelings of depression depressive symptom measurement 748,601
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002112/ScoringFiles/PGS002112.txt.gz
PGS003462
(LDPred2_BMI)
 PGP000456 |
Zhang Y et al. EBioMedicine (2022)
 Body mass index (BMI) body mass index 749,106
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003462/ScoringFiles/PGS003462.txt.gz
PGS002894
(ExPRSweb_DBP_4079-raw_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Diastolic blood pressure diastolic blood pressure 749,859
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002894/ScoringFiles/PGS002894.txt.gz
PGS003838
(height_AFR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Height body height 752,195
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003838/ScoringFiles/PGS003838.txt.gz
PGS003845
(bmi_AFR_LDpred2)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Body mass index (BMI) body mass index 752,209
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003845/ScoringFiles/PGS003845.txt.gz
PGS004094
(prscs.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 755,048
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004094/ScoringFiles/PGS004094.txt.gz
PGS004103
(prscs.CV.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 755,048
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004103/ScoringFiles/PGS004103.txt.gz
PGS002889
(ExPRSweb_DBP_4079-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Diastolic blood pressure diastolic blood pressure 755,822
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002889/ScoringFiles/PGS002889.txt.gz
PGS002057
(portability-ldpred2_454)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Varicose veins Varicose veins 760,630
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002057/ScoringFiles/PGS002057.txt.gz
PGS019925
(Short Sleep MVP EUR)
 PGP000836 |
Wyss AB et al. Sleep (2026)
 Short Sleep short sleep 761,060
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019925/ScoringFiles/PGS019925.txt.gz
PGS002222
(portability-ldpred2_self_harm_thoughts)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ever contemplated self-harm / Recent thoughts of suicide or self-harm Self-injurious behavior 761,279
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002222/ScoringFiles/PGS002222.txt.gz
PGS002048
(portability-ldpred2_411.4)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Coronary atherosclerosis coronary atherosclerosis 762,124
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002048/ScoringFiles/PGS002048.txt.gz
PGS003144
(ExPRSweb_TG_30870-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Triglycerides triglyceride measurement 762,608
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003144/ScoringFiles/PGS003144.txt.gz
PGS004871
(INTERVENE_MegaPRS_Gout)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Gout gout 762,621
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004871/ScoringFiles/PGS004871.txt.gz
PGS002140
(portability-ldpred2_glasses)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Wears glasses or contact lenses eye measurement 762,684
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002140/ScoringFiles/PGS002140.txt.gz
PGS002864
(ExPRSweb_CRP_30710-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 C-reactive protein C-reactive protein measurement 763,400
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002864/ScoringFiles/PGS002864.txt.gz
PGS002098
(portability-ldpred2_abnormal_appetite)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Recent poor appetite or overeating eating disorder 764,146
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002098/ScoringFiles/PGS002098.txt.gz
PGS002029
(portability-ldpred2_272)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Disorders of lipoid metabolism Abnormal circulating lipid concentration 764,390
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002029/ScoringFiles/PGS002029.txt.gz
PGS004872
(INTERVENE_MegaPRS_Prostate_cancer)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Prostate cancer prostate carcinoma 765,876
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004872/ScoringFiles/PGS004872.txt.gz
PGS002115
(portability-ldpred2_drink_alcohol)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Alcohol drinker status alcohol drinking 766,714
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002115/ScoringFiles/PGS002115.txt.gz
PGS003860
(PGS_RE)
 PGP000498 |
Clark R et al. EBioMedicine (2023)
 Refractive error refractive error measurement 767,867
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003860/ScoringFiles/PGS003860.txt.gz - Check Terms/Licenses
PGS019921
(Long Sleep MVP EUR)
 PGP000836 |
Wyss AB et al. Sleep (2026)
 Long Sleep sleep duration trait 769,142
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019921/ScoringFiles/PGS019921.txt.gz
PGS002214
(portability-ldpred2_neutrophil_perc)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Neutrophil percentage neutrophil percentage of leukocytes 769,542
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002214/ScoringFiles/PGS002214.txt.gz
PGS003834
(TC_SAS_CTSLEB)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 Total cholesterol total cholesterol measurement 770,490
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003834/ScoringFiles/PGS003834.txt.gz
PGS003783
(HDL_SAS_CTSLEB)
 PGP000489 |
Zhang H et al. Nat Genet (2023)
 HDL cholesterol high density lipoprotein cholesterol measurement 771,693
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003783/ScoringFiles/PGS003783.txt.gz
PGS002194
(portability-ldpred2_log_reticulocyte)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reticulocyte count reticulocyte count 773,305
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002194/ScoringFiles/PGS002194.txt.gz
PGS002093
(portability-ldpred2_735.3)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hallux valgus (Bunion) Hallux valgus 773,461
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002093/ScoringFiles/PGS002093.txt.gz
PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Hip osteoarthritis osteoarthritis, hip 773,587
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004882/ScoringFiles/PGS004882.txt.gz
PGS002158
(portability-ldpred2_log_ALT)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Alanine aminotransferase serum alanine aminotransferase amount 774,274
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002158/ScoringFiles/PGS002158.txt.gz
PGS002078
(portability-ldpred2_618)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Genital prolapse prolapse of female genital organ 774,553
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002078/ScoringFiles/PGS002078.txt.gz
PGS004683
(height_AFR_ldpred2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 Height body height 774,968
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004683/ScoringFiles/PGS004683.txt.gz
PGS003069
(ExPRSweb_SBP_4080-irnt_LASSOSUM_MGI_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Systolic blood pressure systolic blood pressure 775,138
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003069/ScoringFiles/PGS003069.txt.gz
PGS002203
(portability-ldpred2_lymphocyte_perc)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Lymphocyte percentage lymphocyte percentage of leukocytes 775,312
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002203/ScoringFiles/PGS002203.txt.gz
PGS003469
(LDPred2_HOMA_B)
 PGP000456 |
Zhang Y et al. EBioMedicine (2022)
 HOMA-B HOMA-B 775,825
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003469/ScoringFiles/PGS003469.txt.gz
PGS003470
(LDPred2_HOMA_IR)
 PGP000456 |
Zhang Y et al. EBioMedicine (2022)
 HOMA-IR HOMA-IR 775,999
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003470/ScoringFiles/PGS003470.txt.gz
PGS003472
(LDPred2_HrRt)
 PGP000456 |
Zhang Y et al. EBioMedicine (2022)
 Heart rate heart rate 776,860
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003472/ScoringFiles/PGS003472.txt.gz
PGS004055
(megaprs.auto.GCST006085.Prostate_cancer)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Prostate cancer prostate carcinoma 777,255
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004055/ScoringFiles/PGS004055.txt.gz
PGS004071
(megaprs.CV.GCST006085.Prostate_cancer)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Prostate cancer prostate carcinoma 777,255
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004071/ScoringFiles/PGS004071.txt.gz
PGS003994
(dbslmm.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 778,205
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003994/ScoringFiles/PGS003994.txt.gz
PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 778,275
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004163/ScoringFiles/PGS004163.txt.gz
PGS002177
(portability-ldpred2_log_HLR_reticulocyte)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 High light scatter reticulocyte count reticulocyte amount 780,048
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002177/ScoringFiles/PGS002177.txt.gz
PGS002058
(portability-ldpred2_455)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Hemorrhoids hemorrhoid 780,418
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002058/ScoringFiles/PGS002058.txt.gz
PGS002165
(portability-ldpred2_log_cystatinC)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Cystatin C cystatin C measurement 781,302
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002165/ScoringFiles/PGS002165.txt.gz
PGS004134
(sbayesr.auto.GCST002783.BMI)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Body mass index (BMI) body mass index 782,021
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004134/ScoringFiles/PGS004134.txt.gz
PGS012556
(BMI_EAS_MIXPRSplus)
 PGP000799 |
Xu L et al. Nat Genet (2026)
 Body mass index (BMI) body mass index 782,322
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS012556/ScoringFiles/PGS012556.txt.gz
PGS004051
(megaprs.auto.GCST004131.IBD)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Inflammatory bowel disease (IBD) inflammatory bowel disease 784,928
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004051/ScoringFiles/PGS004051.txt.gz
Showing 4301 to 4350 of 6991 rows