Latest Release - Feb. 20, 2024

New Publications (12)

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000588 0 1 Marshall HN High Polygenic Risk Is Associated with Earlier Trabeculectomy in Patients with Primary Open-Angle Glaucoma. Ophthalmol Glaucoma 13/07/2022 10.1016/j.ogla.2022.06.009 35842105
PGP000591 2 2 Wang X Genetic Susceptibility to Atrial Fibrillation Identified via Deep Learning of 12-Lead Electrocardiograms. Circ Genom Precis Med 06/06/2023 10.1161/circgen.122.003808 37278238
PGP000592 1 1 Wu Y 150 risk variants for diverticular disease of intestine prioritize cell types and enable polygenic prediction of disease susceptibility. Cell Genom 05/06/2023 10.1016/j.xgen.2023.100326 37492107
PGP000590 1 1 Shieh Y Development and testing of a polygenic risk score for breast cancer aggressiveness. NPJ Precis Oncol 15/05/2023 10.1038/s41698-023-00382-z 37188791
PGP000583 0 1 Dueñas N Ability of a polygenic risk score to refine colorectal cancer risk in Lynch syndrome. J Med Genet 15/06/2023 10.1136/jmg-2023-109344 37321833
PGP000586 0 1 Khurshid S Predictive Accuracy of a Clinical and Genetic Risk Model for Atrial Fibrillation. Circ Genom Precis Med 31/08/2021 10.1161/circgen.121.003355 34463125
PGP000587 0 1 Luo M Accelerometer-measured intensity-specific physical activity, genetic risk and incident type 2 diabetes: a prospective cohort study. Br J Sports Med 05/06/2023 10.1136/bjsports-2022-106653 37277158
PGP000589 0 1 Mur P Non-Lynch Familial and Early-Onset Colorectal Cancer Explained by Accumulation of Low-Risk Genetic Variants. Cancers (Basel) 31/07/2021 10.3390/cancers13153857 34359758
PGP000584 1 1 Forthman KL Transdiagnostic behavioral and genetic contributors to repetitive negative thinking: A machine learning approach. J Psychiatr Res 05/05/2023 10.1016/j.jpsychires.2023.05.039 37178517
PGP000562 3 3 Youssef Y O High-Resolution Genotyping of Formalin-Fixed Tissue Accurately Estimates Polygenic Risk Scores in Human Diseases. Lab Invest 15/01/2024 10.1016/j.labinv.2024.100325 38220043
PGP000585 2 2 Hawkes G Genetic evidence that high BMI in childhood has a protective effect on intermediate diabetes traits, including measures of insulin sensitivity and secretion, after accounting for BMI in adulthood. Diabetologia 06/06/2023 10.1007/s00125-023-05923-6 37280435
PGP000582 2 2 Gorman BR Distinctive cross-ancestry genetic architecture for age-related macular degeneration medRxivPre 21/08/2022 10.1101/2022.08.16.22278855

New Polygenic Scores (12)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS004579
(BRCA_PRSCS)
PGP000562 |
Youssef Y O et al. Lab Invest (2024)
Breast cancer breast carcinoma 1,088,163
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004579/ScoringFiles/PGS004579.txt.gz
PGS004580
(CRC_PRSCS)
PGP000562 |
Youssef Y O et al. Lab Invest (2024)
Colorectal cancer colorectal carcinoma 1,099,906
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004580/ScoringFiles/PGS004580.txt.gz
PGS004581
(PRCA_PRSCS)
PGP000562 |
Youssef Y O et al. Lab Invest (2024)
Prostate cancer prostate carcinoma 1,102,292
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004581/ScoringFiles/PGS004581.txt.gz
PGS004606
(AMD-IAMDGC-EUR)
PGP000582 |
Gorman BR et al. medRxiv (2022)
|Pre
Age-related macular degeneration age-related macular degeneration 1,000,946
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004606/ScoringFiles/PGS004606.txt.gz
PGS004607
(AMD-MVP-AFR)
PGP000582 |
Gorman BR et al. medRxiv (2022)
|Pre
Age-related macular degeneration age-related macular degeneration 1,067,520
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004607/ScoringFiles/PGS004607.txt.gz
PGS004608
(neuroticism)
PGP000584 |
Forthman KL et al. J Psychiatr Res (2023)
Neuroticism neuroticism measurement 1,000,537
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004608/ScoringFiles/PGS004608.txt.gz
PGS004609
(adult_BMI)
PGP000585 |
Hawkes G et al. Diabetologia (2023)
Body mass index (BMI) body mass index 1,127
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004609/ScoringFiles/PGS004609.txt.gz
PGS004610
(child_BMI)
PGP000585 |
Hawkes G et al. Diabetologia (2023)
Body mass index (BMI) body mass index 306
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004610/ScoringFiles/PGS004610.txt.gz
PGS004611
(RORP_PRS)
PGP000590 |
Shieh Y et al. NPJ Precis Oncol (2023)
Breast cancer breast carcinoma 76
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004611/ScoringFiles/PGS004611.txt.gz
PGS004612
(PRSECG_AI)
PGP000591 |
Wang X et al. Circ Genom Precis Med (2023)
ECG-AI predicted 5-year risk of atrial fibrillation atrial fibrillation 1,117,399
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004612/ScoringFiles/PGS004612.txt.gz
PGS004613
(PRSCHARGE_AF)
PGP000591 |
Wang X et al. Circ Genom Precis Med (2023)
CHARGE-AF predicted 5-year risk of atrial fibrillation atrial fibrillation 1,117,400
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004613/ScoringFiles/PGS004613.txt.gz
PGS004614
(DivD_SNPWeights)
PGP000592 |
Wu Y et al. Cell Genom (2023)
Diverticular disease diverticular disease 1,082,282
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004614/ScoringFiles/PGS004614.txt.gz