|
PGS Publication/Study ID (PGP) |
PGS Developed |
PGS Evaluated |
First Author | Title | Journal Name |
Publication Date |
Digital object identifier (doi) |
PubMed ID (PMID) |
|---|---|---|---|---|---|---|---|---|
| PGP000564 | 1 | 1 | Xin J | Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment. | Nat Commun | 08/04/2024 | 10.1038/s41467-024-47204-9 | 38589358 |
| PGP000643 | 1 | 1 | Tian J | Developing an optimal stratification model for colorectal cancer screening and reducing racial disparities in multi-center population-based studies. | Genome Med | 13/06/2024 | 10.1186/s13073-024-01355-y | 38872215 |
| PGP000653 | 0 | 1 | Tynkkynen NP | Associations of polygenic inheritance of physical activity with aerobic fitness, cardiometabolic risk factors and diseases: the HUNT study. | Eur J Epidemiol | 21/08/2023 | 10.1007/s10654-023-01029-w | 37603226 |
| PGP000618 | 18 | 18 | Jermy B | A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk. | Nat Commun | 12/06/2024 | 10.1038/s41467-024-48938-2 | 38866767 |
| PGP000651 | 0 | 1 | Liang H | Association of genetic risk and lifestyle with incident adult-onset asthma in the UK Biobank cohort. | ERJ Open Res | 01/03/2023 | 10.1183/23120541.00499-2022 | 37057096 |
| PGP000654 | 1 | 1 | Huang Y | Sexual Differences in Genetic Predisposition of Coronary Artery Disease. | Circ Genom Precis Med | 17/12/2020 | 10.1161/circgen.120.003147 | 33332181 |
| PGP000652 | 1 | 1 | Wang N | Long-term night shift work is associated with the risk of atrial fibrillation and coronary heart disease. | Eur Heart J | 01/10/2021 | 10.1093/eurheartj/ehab505 | 34374755 |
| PGP000655 | 1 | 2 | El-Boraie A | Transferability of Ancestry-Specific and Cross-Ancestry CYP2A6 Activity Genetic Risk Scores in African and European Populations. | Clin Pharmacol Ther | 01/01/2021 | 10.1002/cpt.2135 | 33300144 |
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS004586 (PPS_CRC) |
PGP000564 | Xin J et al. Nat Commun (2024) |
Colorectal cancer | colorectal carcinoma | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004586/ScoringFiles/PGS004586.txt.gz |
| PGS004869 (INTERVENE_MegaPRS_breast_cancer) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Breast cancer | breast carcinoma | 872,060 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004869/ScoringFiles/PGS004869.txt.gz | |
| PGS004870 (INTERVENE_MegaPRS_T2D) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 930,506 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004870/ScoringFiles/PGS004870.txt.gz | |
| PGS004871 (INTERVENE_MegaPRS_Gout) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Gout | gout | 762,621 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004871/ScoringFiles/PGS004871.txt.gz | |
| PGS004872 (INTERVENE_MegaPRS_Prostate_cancer) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Prostate cancer | prostate carcinoma | 765,876 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004872/ScoringFiles/PGS004872.txt.gz | |
| PGS004873 (INTERVENE_MegaPRS_RA) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Rheumatoid arthritis | rheumatoid arthritis | 551,074 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004873/ScoringFiles/PGS004873.txt.gz | |
| PGS004874 (INTERVENE_MegaPRS_T1D) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Type 1 diabetes (T1D) | type 1 diabetes mellitus | 56,916 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004874/ScoringFiles/PGS004874.txt.gz | |
| PGS004875 (INTERVENE_MegaPRS_AllCancers) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
All Cancers | cancer | 818,872 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004875/ScoringFiles/PGS004875.txt.gz |
| PGS004876 (INTERVENE_MegaPRS_Appendicitis) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Appendicitis | appendicitis | 601,835 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004876/ScoringFiles/PGS004876.txt.gz |
| PGS004877 (INTERVENE_MegaPRS_Asthma) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Asthma | asthma | 870,454 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004877/ScoringFiles/PGS004877.txt.gz | |
| PGS004878 (INTERVENE_MegaPRS_Atrial_fibrillation) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Atrial fibrillation | atrial fibrillation | 785,779 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004878/ScoringFiles/PGS004878.txt.gz | |
| PGS004879 (INTERVENE_MegaPRS_CHD) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Coronary heart disease | coronary artery disease | 610,677 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004879/ScoringFiles/PGS004879.txt.gz | |
| PGS004880 (INTERVENE_MegaPRS_Colorectal_cancer) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Colorectal cancer | colorectal carcinoma | 843,248 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004880/ScoringFiles/PGS004880.txt.gz | |
| PGS004881 (INTERVENE_MegaPRS_Epilepsy) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Epilepsy | epilepsy | 605,432 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004881/ScoringFiles/PGS004881.txt.gz | |
| PGS004882 (INTERVENE_MegaPRS_Hip_osteoarthritis) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Hip osteoarthritis | osteoarthritis, hip | 773,587 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004882/ScoringFiles/PGS004882.txt.gz | |
| PGS004883 (INTERVENE_MegaPRS_Knee_osteoarthritis) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Knee osteoarthritis | osteoarthritis, knee | 952,133 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004883/ScoringFiles/PGS004883.txt.gz | |
| PGS004884 (INTERVENE_MegaPRS_Lung_cancer) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Lung cancer | lung carcinoma | 655,479 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004884/ScoringFiles/PGS004884.txt.gz | |
| PGS004885 (INTERVENE_MegaPRS_MDD) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Major depressive disorder | major depressive disorder | 801,544 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004885/ScoringFiles/PGS004885.txt.gz | |
| PGS004886 (INTERVENE_MegaPRS_Melanoma) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Melanoma | melanoma | 692,834 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004886/ScoringFiles/PGS004886.txt.gz | |
| PGS004912 (PRS183) |
PGP000643 | Tian J et al. Genome Med (2024) |
Colorectal neoplasm | colorectal carcinoma | 183 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004912/ScoringFiles/PGS004912.txt.gz | |
| PGS004920 (GRS166_AF) |
PGP000652 | Wang N et al. Eur Heart J (2021) |
Atrial fibrillation | atrial fibrillation | 166 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004920/ScoringFiles/PGS004920.txt.gz |
| PGS004921 (CAD-GRS) |
PGP000654 | Huang Y et al. Circ Genom Precis Med (2020) |
Coronary artery disease | coronary artery disease | 161 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004921/ScoringFiles/PGS004921.txt.gz | |
| PGS004922 (wGRS_AFR) |
PGP000655 | El-Boraie A et al. Clin Pharmacol Ther (2021) |
Nicotine metabolite ratio | nicotine metabolite ratio | 14 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004922/ScoringFiles/PGS004922.txt.gz |