| PGS Publication/Study ID (PGP) | PGS Developed | PGS Evaluated | First Author | Title | Journal Name | Publication Date | Digital object identifier (doi) | PubMed ID (PMID) |
|---|---|---|---|---|---|---|---|---|
| PGP000305 | 1 | 1 | Siddiqui MK | Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function. | Diabetologia | 05/03/2022 | 10.1007/s00125-022-05671-z | 35247066 |
| PGP000306 | 0 | 1 | Thompson PL | Common genetic variants do not predict recurrent events in coronary heart disease patients. | BMC Cardiovasc Disord | 09/03/2022 | 10.1186/s12872-022-02520-0 | 35264114 |
| PGP000311 | 0 | 1 | Olmastroni E | Twelve Variants Polygenic Score for Low-Density Lipoprotein Cholesterol Distribution in a Large Cohort of Patients With Clinically Diagnosed Familial Hypercholesterolemia With or Without Causative Mutations. | J Am Heart Assoc | 24/03/2022 | 10.1161/jaha.121.023668 | 35322671 |
| PGP000308 | 0 | 1 | Schaid DJ | Polygenic risk for prostate cancer: Decreasing relative risk with age but little impact on absolute risk. | Am J Hum Genet | 23/03/2022 | 10.1016/j.ajhg.2022.03.008 | 35353984 |
| PGP000309 | 1 | 1 | Bellenguez C | New insights into the genetic etiology of Alzheimer's disease and related dementias. | Nat Genet | 04/04/2022 | 10.1038/s41588-022-01024-z | 35379992 |
| PGP000310 | 1 | 1 | Canzian F | A polygenic risk score for multiple myeloma risk prediction. | Eur J Hum Genet | 30/11/2021 | 10.1038/s41431-021-00986-8 | 34845334 |
| PGP000312 | 2 | 2 | Schnurr TM | Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD. | Hepatol Commun | 15/03/2022 | 10.1002/hep4.1932 | 35293152 |
| PGP000304 | 1 | 1 | Nauffal V | Monogenic and Polygenic Contributions to QTc Prolongation in the Population. | Circulation | 07/04/2022 | 10.1161/circulationaha.121.057261 | 35389749 |
| PGP000307 | 2 | 2 | Forrest IS | Genetic and phenotypic profiling of supranormal ejection fraction reveals decreased survival and underdiagnosed heart failure. | Eur J Heart Fail | 12/03/2022 | 10.1002/ejhf.2482 | 35278270 |
| PGP000271 | 5 | 5 | Mars N | Genome-wide risk prediction of common diseases across ancestries in one million people. | Cell Genom | 13/04/2022 | 10.1016/j.xgen.2022.100118 | — |
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants | Ancestry distribution | Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS002240 (prscs_prostatecancer) |
PGP000271 | Mars N et al. Cell Genom (2022) |
Prostate cancer | prostate carcinoma | 1,092,093 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002240/ScoringFiles/PGS002240.txt.gz | |
| PGS002241 (ldpred_prostatecancer) |
PGP000271 | Mars N et al. Cell Genom (2022) |
Prostate cancer | prostate carcinoma | 6,497,734 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002241/ScoringFiles/PGS002241.txt.gz | |
| PGS002242 (ldpred_breastcancer) |
PGP000271 | Mars N et al. Cell Genom (2022) |
Breast cancer | breast carcinoma | 6,494,889 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002242/ScoringFiles/PGS002242.txt.gz | |
| PGS002243 (ldpred_t2d) |
PGP000271 | Mars N et al. Cell Genom (2022) |
Type 2 diabetes | type 2 diabetes mellitus | 6,431,973 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002243/ScoringFiles/PGS002243.txt.gz | |
| PGS002244 (ldpred_cad) |
PGP000271 | Mars N et al. Cell Genom (2022) |
Coronary artery disease | coronary artery disease | 6,576,338 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002244/ScoringFiles/PGS002244.txt.gz | |
| PGS002276 (QTc_PRS-CS) |
PGP000304 | Nauffal V et al. Circulation (2022) |
QTc duration | QT interval | 1,110,494 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002276/ScoringFiles/PGS002276.txt.gz | |
| PGS002277 (pPS_Insulin_secretion_1) |
PGP000305 | Siddiqui MK et al. Diabetologia (2022) |
Type 2 diabetes (based on SNPs associated with insulin secretion) | type 2 diabetes mellitus | 8 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002277/ScoringFiles/PGS002277.txt.gz |
| PGS002278 (GRS16_snLVEF) |
PGP000307 | Forrest IS et al. Eur J Heart Fail (2022) |
Supranormal left ventricular ejection fraction | left ventricular ejection fraction measurement | 16 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002278/ScoringFiles/PGS002278.txt.gz |
| PGS002279 (GRS22_rLVEF) |
PGP000307 | Forrest IS et al. Eur J Heart Fail (2022) |
Reduced left ventricular ejection fraction | left ventricular ejection fraction measurement | 22 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002279/ScoringFiles/PGS002279.txt.gz |
| PGS002280 (GRS83_AD) |
PGP000309 | Bellenguez C et al. Nat Genet (2022) |
Alzheimer’s disease | Alzheimer disease | 83 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002280/ScoringFiles/PGS002280.txt.gz |
| PGS002281 (PRS23_MM) |
PGP000310 | Canzian F et al. Eur J Hum Genet (2021) |
Multiple myeloma | multiple myeloma | 23 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002281/ScoringFiles/PGS002281.txt.gz |
| PGS002282 (GRS68_NAFLD) |
PGP000312 | Schnurr TM et al. Hepatol Commun (2022) |
Nonalcoholic fatty liver disease | non-alcoholic fatty liver disease | 68 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002282/ScoringFiles/PGS002282.txt.gz |
| PGS002283 (GRS15_NAFLD) |
PGP000312 | Schnurr TM et al. Hepatol Commun (2022) |
Nonalcoholic fatty liver disease | non-alcoholic fatty liver disease | 15 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002283/ScoringFiles/PGS002283.txt.gz |