Latest Release - April 13, 2022

New Publications (10)

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000305 1 1 Siddiqui MK Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function. Diabetologia 05/03/2022 10.1007/s00125-022-05671-z 35247066
PGP000306 0 1 Thompson PL Common genetic variants do not predict recurrent events in coronary heart disease patients. BMC Cardiovasc Disord 09/03/2022 10.1186/s12872-022-02520-0 35264114
PGP000311 0 1 Olmastroni E Twelve Variants Polygenic Score for Low-Density Lipoprotein Cholesterol Distribution in a Large Cohort of Patients With Clinically Diagnosed Familial Hypercholesterolemia With or Without Causative Mutations. J Am Heart Assoc 24/03/2022 10.1161/jaha.121.023668 35322671
PGP000308 0 1 Schaid DJ Polygenic risk for prostate cancer: Decreasing relative risk with age but little impact on absolute risk. Am J Hum Genet 23/03/2022 10.1016/j.ajhg.2022.03.008 35353984
PGP000309 1 1 Bellenguez C New insights into the genetic etiology of Alzheimer's disease and related dementias. Nat Genet 04/04/2022 10.1038/s41588-022-01024-z 35379992
PGP000310 1 1 Canzian F A polygenic risk score for multiple myeloma risk prediction. Eur J Hum Genet 30/11/2021 10.1038/s41431-021-00986-8 34845334
PGP000312 2 2 Schnurr TM Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD. Hepatol Commun 15/03/2022 10.1002/hep4.1932 35293152
PGP000304 1 1 Nauffal V Monogenic and Polygenic Contributions to QTc Prolongation in the Population. Circulation 07/04/2022 10.1161/circulationaha.121.057261 35389749
PGP000307 2 2 Forrest IS Genetic and phenotypic profiling of supranormal ejection fraction reveals decreased survival and underdiagnosed heart failure. Eur J Heart Fail 12/03/2022 10.1002/ejhf.2482 35278270
PGP000271 5 5 Mars N Genome-wide risk prediction of common diseases across ancestries in one million people. Cell Genom 13/04/2022 10.1016/j.xgen.2022.100118

New Polygenic Scores (13)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
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Additional Asian Ancestries
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Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution Scoring File (FTP Link)
PGS002240
(prscs_prostatecancer)
PGP000271 |
Mars N et al. Cell Genom (2022)
Prostate cancer prostate carcinoma 1,092,093
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002240/ScoringFiles/PGS002240.txt.gz
PGS002241
(ldpred_prostatecancer)
PGP000271 |
Mars N et al. Cell Genom (2022)
Prostate cancer prostate carcinoma 6,497,734
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002241/ScoringFiles/PGS002241.txt.gz
PGS002242
(ldpred_breastcancer)
PGP000271 |
Mars N et al. Cell Genom (2022)
Breast cancer breast carcinoma 6,494,889
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002242/ScoringFiles/PGS002242.txt.gz
PGS002243
(ldpred_t2d)
PGP000271 |
Mars N et al. Cell Genom (2022)
Type 2 diabetes type 2 diabetes mellitus 6,431,973
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002243/ScoringFiles/PGS002243.txt.gz
PGS002244
(ldpred_cad)
PGP000271 |
Mars N et al. Cell Genom (2022)
Coronary artery disease coronary artery disease 6,576,338
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002244/ScoringFiles/PGS002244.txt.gz
PGS002276
(QTc_PRS-CS)
PGP000304 |
Nauffal V et al. Circulation (2022)
QTc duration QT interval 1,110,494
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002276/ScoringFiles/PGS002276.txt.gz
PGS002277
(pPS_Insulin_secretion_1)
PGP000305 |
Siddiqui MK et al. Diabetologia (2022)
Type 2 diabetes (based on SNPs associated with insulin secretion) type 2 diabetes mellitus 8
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002277/ScoringFiles/PGS002277.txt.gz
PGS002278
(GRS16_snLVEF)
PGP000307 |
Forrest IS et al. Eur J Heart Fail (2022)
Supranormal left ventricular ejection fraction left ventricular ejection fraction measurement 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002278/ScoringFiles/PGS002278.txt.gz
PGS002279
(GRS22_rLVEF)
PGP000307 |
Forrest IS et al. Eur J Heart Fail (2022)
Reduced left ventricular ejection fraction left ventricular ejection fraction measurement 22
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002279/ScoringFiles/PGS002279.txt.gz
PGS002280
(GRS83_AD)
PGP000309 |
Bellenguez C et al. Nat Genet (2022)
Alzheimer’s disease Alzheimer disease 83
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002280/ScoringFiles/PGS002280.txt.gz
PGS002281
(PRS23_MM)
PGP000310 |
Canzian F et al. Eur J Hum Genet (2021)
Multiple myeloma multiple myeloma 23
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002281/ScoringFiles/PGS002281.txt.gz
PGS002282
(GRS68_NAFLD)
PGP000312 |
Schnurr TM et al. Hepatol Commun (2022)
Nonalcoholic fatty liver disease non-alcoholic fatty liver disease 68
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002282/ScoringFiles/PGS002282.txt.gz
PGS002283
(GRS15_NAFLD)
PGP000312 |
Schnurr TM et al. Hepatol Commun (2022)
Nonalcoholic fatty liver disease non-alcoholic fatty liver disease 15
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002283/ScoringFiles/PGS002283.txt.gz