Trait: arthropathy

Trait Information
Identifier MONDO_0006816
Description Any disorder of the joints. [NCIT: C35760]
Trait category
Other trait
Synonyms 25 synonyms
  • Joint ankylosis of the ankle and foot
  • Joint ankylosis of the forearm
  • Joint ankylosis of the hand
  • Joint ankylosis of the lower leg
  • Joint ankylosis of the pelvic region and thigh
  • Joint ankylosis of the shoulder region
  • Joint ankylosis of the upper arm
  • Joint disorder
  • ankylosis of ankle and foot joint
  • ankylosis of forearm joint
  • ankylosis of hand joint
  • ankylosis of joint of multiple sites
  • ankylosis of joint of pelvic region and thigh
  • ankylosis of joint of shoulder region
  • ankylosis of lower leg joint
  • ankylosis of multiple joints
  • ankylosis of upper arm joint
  • arthropathy
  • disease of skeletal joint
  • disease or disorder of skeletal joint
  • disorder of skeletal joint
  • disorder, Joint
  • infectious arthropathy
  • skeletal joint disease
  • skeletal joint disease or disorder
Child trait(s) 17 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows all PGS for "arthropathy" and any child terms of this trait in the EFO hierarchy by default.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000114
(GRS-JIA-20)
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Juvenile Idiopathic Arthritis juvenile idiopathic arthritis 26
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000114/ScoringFiles/PGS000114.txt.gz
PGS000194
(G-PROB_Rapos)
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Rheumatoid arthritis (CCP-negative) ACPA-positive rheumatoid arthritis 114
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000194/ScoringFiles/PGS000194.txt.gz
PGS000195
(G-PROB_Raneg)
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Rheumatoid arthritis (CCP-negative) ACPA-negative rheumatoid arthritis 96
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000195/ScoringFiles/PGS000195.txt.gz
PGS000197
(G-PROB_SpA)
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Spondyloarthroparthy spondyloarthropathy 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000197/ScoringFiles/PGS000197.txt.gz
PGS000198
(G-PROB_PsA)
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Psoriatic arthritis psoriatic arthritis 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000198/ScoringFiles/PGS000198.txt.gz
PGS000324
(GRS-JIA-ERA-20)
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Enthesitis-related Juvenile Idiophatic Arthritis enthesitis-related juvenile idiopathic arthritis 138
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000324/ScoringFiles/PGS000324.txt.gz
PGS000325
(GRS-JIA-Oli-20)
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Oligoarthritis Juvenile Idiophatic Arthritis oligoarticular juvenile idiopathic arthritis 21
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000325/ScoringFiles/PGS000325.txt.gz
PGS000326
(GRS-JIA-RFN-20)
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Rheumatoid-factor-negative Polyarthritis (Juvenile Idiophatic Arthritis) rheumatoid factor-negative juvenile idiopathic arthritis 12
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000326/ScoringFiles/PGS000326.txt.gz
PGS000342
(wGRS_PsA)
 PGP000111 |
Smith MP et al. J Psoriasis Psoriatic Arthritis (2020)
 Psoriatic arthritis psoriatic arthritis 11
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000342/ScoringFiles/PGS000342.txt.gz
PGS000343
(wGRS_PsA_HLA)
 PGP000111 |
Smith MP et al. J Psoriasis Psoriatic Arthritis (2020)
 Psoriatic arthritis psoriatic arthritis 5
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000343/ScoringFiles/PGS000343.txt.gz
PGS000967
(GBE_HC1221)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Coxarthrosis [arthrosis of hip] (time-to-event) osteoarthritis, hip 634
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000967/ScoringFiles/PGS000967.txt.gz
PGS001110
(GBE_HC1209)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reactive arthropathies (time-to-event) reactive arthritis 6
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001110/ScoringFiles/PGS001110.txt.gz
PGS001135
(GBE_HC78)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Arthritis (nos) arthritic joint disease 1,028
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001135/ScoringFiles/PGS001135.txt.gz
PGS001192
(GBE_HC1222)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Gonarthrosis [arthrosis of knee] (time-to-event) osteoarthritis, knee 4,525
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001192/ScoringFiles/PGS001192.txt.gz
PGS001267
(GBE_HC422)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ankylosing spondylitis ankylosing spondylitis 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001267/ScoringFiles/PGS001267.txt.gz
PGS001268
(GBE_HC1242)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ankylosing spondylitis (time-to-event) ankylosing spondylitis 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001268/ScoringFiles/PGS001268.txt.gz
PGS001287
(GBE_HC91)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Psoriatic arthropathy psoriatic arthritis 36
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001287/ScoringFiles/PGS001287.txt.gz
PGS001290
(GBE_HC376)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Osteoarthritis osteoarthritis 579
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001290/ScoringFiles/PGS001290.txt.gz
PGS001309
(GBE_HC1212)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Other rheumatoid arthritis (time-to-event) rheumatoid arthritis 323
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001309/ScoringFiles/PGS001309.txt.gz
PGS001310
(GBE_HC430)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Rheumatoid arthritis rheumatoid arthritis 175
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001310/ScoringFiles/PGS001310.txt.gz
PGS001311
(GBE_HC1211)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Seropositive rheumatoid arthritis (time-to-event) rheumatoid arthritis 3
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001311/ScoringFiles/PGS001311.txt.gz
PGS001875
(portability-PLR_714.1)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Rheumatoid arthritis rheumatoid arthritis 256
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001875/ScoringFiles/PGS001875.txt.gz
PGS001876
(portability-PLR_715.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ankylosing spondylitis ankylosing spondylitis 85
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001876/ScoringFiles/PGS001876.txt.gz
PGS001879
(portability-PLR_727.4)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ganglion and cyst of synovium, tendon, and bursa ganglion or cyst of synovium/tendon/bursa 210
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001879/ScoringFiles/PGS001879.txt.gz
PGS001882
(portability-PLR_740)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Osteoarthrosis osteoarthritis 11,451
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001882/ScoringFiles/PGS001882.txt.gz
PGS002088
(portability-ldpred2_714.1)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Rheumatoid arthritis rheumatoid arthritis 95,083
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002088/ScoringFiles/PGS002088.txt.gz
PGS002089
(portability-ldpred2_715.2)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Ankylosing spondylitis ankylosing spondylitis 22,026
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002089/ScoringFiles/PGS002089.txt.gz
PGS002094
(portability-ldpred2_740)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Osteoarthrosis osteoarthritis 827,887
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002094/ScoringFiles/PGS002094.txt.gz
PGS002260
(PRS_RA)
 PGP000286 |
Honda S et al. Arthritis Rheumatol (2022)
 Rheumatoid arthritis rheumatoid arthritis 43,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002260/ScoringFiles/PGS002260.txt.gz
PGS002728
(PRS_hip)
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Hip osteoarthritis osteoarthritis, hip 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002728/ScoringFiles/PGS002728.txt.gz
PGS002729
(PRS_knee)
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Knee osteoarthritis osteoarthritis, knee 24
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002729/ScoringFiles/PGS002729.txt.gz
PGS002745
(metaPGS_RA)
 PGP000357 |
Ishigaki K et al. Nat Genet (2022)
 Rheumatoid arthritis rheumatoid arthritis 2,575
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002745/ScoringFiles/PGS002745.txt.gz
PGS002749
(PRS10_TKR)
 PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
 Total knee replacement total knee arthroplasty,
osteoarthritis, knee		 10
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002749/ScoringFiles/PGS002749.txt.gz
PGS002750
(PRS37_THR)
 PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
 Total hip replacement total hip arthroplasty,
osteoarthritis, hip		 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002750/ScoringFiles/PGS002750.txt.gz
PGS002763
(Hip_osteoarthritis_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Hip osteoarthritis osteoarthritis, hip 1,052,273
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002763/ScoringFiles/PGS002763.txt.gz
PGS002767
(Knee_osteoarthritis_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Knee osteoarthritis osteoarthritis, knee 1,052,275
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002767/ScoringFiles/PGS002767.txt.gz
PGS002769
(Rheumatoid_arthritis_prscs)
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Seropositive rheumatoid arthritis rheumatoid arthritis 1,083,565
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002769/ScoringFiles/PGS002769.txt.gz
PGS003420
(PRS100_PRScs)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 100
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003420/ScoringFiles/PGS003420.txt.gz
PGS003421
(PRS16_C+T)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003421/ScoringFiles/PGS003421.txt.gz
PGS003422
(PRS16_PRSice2)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 16
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003422/ScoringFiles/PGS003422.txt.gz
PGS003423
(PRS100_Lassosum)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 100
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003423/ScoringFiles/PGS003423.txt.gz
PGS003424
(PRS100_LDpred2)
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Ankylosing spondylitis ankylosing spondylitis 100
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003424/ScoringFiles/PGS003424.txt.gz
PGS003994
(dbslmm.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 778,205
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003994/ScoringFiles/PGS003994.txt.gz
PGS004010
(lassosum.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 27,045
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004010/ScoringFiles/PGS004010.txt.gz
PGS004021
(lassosum.CV.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 315,740
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004021/ScoringFiles/PGS004021.txt.gz
PGS004049
(ldpred2.CV.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 373,627
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004049/ScoringFiles/PGS004049.txt.gz
PGS004064
(megaprs.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 402,214
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004064/ScoringFiles/PGS004064.txt.gz
PGS004079
(megaprs.CV.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 402,214
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004079/ScoringFiles/PGS004079.txt.gz
PGS004094
(prscs.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 755,048
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004094/ScoringFiles/PGS004094.txt.gz
PGS004103
(prscs.CV.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 755,048
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004103/ScoringFiles/PGS004103.txt.gz
PGS004118
(pt_clump.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 91
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004118/ScoringFiles/PGS004118.txt.gz
PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 155
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004133/ScoringFiles/PGS004133.txt.gz
PGS004148
(sbayesr.auto.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 671,211
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004148/ScoringFiles/PGS004148.txt.gz
PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 778,275
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004163/ScoringFiles/PGS004163.txt.gz
PGS004255
(GenoBoost_rheumatoid_arthritis_0)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Rheumatoid arthritis rheumatoid arthritis 30
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004255/ScoringFiles/PGS004255.txt.gz
PGS004256
(GenoBoost_rheumatoid_arthritis_1)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Rheumatoid arthritis rheumatoid arthritis 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004256/ScoringFiles/PGS004256.txt.gz
PGS004257
(GenoBoost_rheumatoid_arthritis_2)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Rheumatoid arthritis rheumatoid arthritis 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004257/ScoringFiles/PGS004257.txt.gz
PGS004258
(GenoBoost_rheumatoid_arthritis_3)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Rheumatoid arthritis rheumatoid arthritis 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004258/ScoringFiles/PGS004258.txt.gz
PGS004259
(GenoBoost_rheumatoid_arthritis_4)
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Rheumatoid arthritis rheumatoid arthritis 20
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004259/ScoringFiles/PGS004259.txt.gz
PGS004326
(PRS154_RA)
 PGP000560 |
Zhang J et al. Environ Health Perspect (2023)
 Rheumatoid arthritis rheumatoid arthritis 154
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004326/ScoringFiles/PGS004326.txt.gz
PGS004477
(disease.M13.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M13 (Other arthritis) arthritic joint disease 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004477/ScoringFiles/PGS004477.txt.gz
PGS004478
(disease.M16.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M16 (Coxarthrosis [arthrosis of hip]) osteoarthritis, hip 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004478/ScoringFiles/PGS004478.txt.gz
PGS004479
(disease.M17.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M17 (Gonarthrosis [arthrosis of knee]) osteoarthritis, knee 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004479/ScoringFiles/PGS004479.txt.gz
PGS004480
(disease.M19.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M19 (Other arthrosis) arthropathy 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004480/ScoringFiles/PGS004480.txt.gz
PGS004483
(disease.M25.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M25 (Other joint disorders, not elsewhere classified) arthropathy 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004483/ScoringFiles/PGS004483.txt.gz
PGS004486
(disease.M51.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M51 (Other intervertebral disk disorders) Intervertebral Disc Displacement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004486/ScoringFiles/PGS004486.txt.gz
PGS004547
(meta.M13.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M13 (Other arthritis) arthritic joint disease 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004547/ScoringFiles/PGS004547.txt.gz
PGS004548
(meta.M16.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M16 (Coxarthrosis [arthrosis of hip]) osteoarthritis, hip 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004548/ScoringFiles/PGS004548.txt.gz
PGS004549
(meta.M17.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M17 (Gonarthrosis [arthrosis of knee]) osteoarthritis, knee 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004549/ScoringFiles/PGS004549.txt.gz
PGS004550
(meta.M19.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M19 (Other arthrosis) arthropathy 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004550/ScoringFiles/PGS004550.txt.gz
PGS004553
(meta.M25.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M25 (Other joint disorders, not elsewhere classified) arthropathy 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004553/ScoringFiles/PGS004553.txt.gz
PGS004556
(meta.M51.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 M51 (Other intervertebral disk disorders) Intervertebral Disc Displacement 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004556/ScoringFiles/PGS004556.txt.gz
PGS004817
(RA_PRSmix_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Rheumatoid Arthritis rheumatoid arthritis 786,048
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004817/ScoringFiles/PGS004817.txt.gz
PGS004818
(RA_PRSmix_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Rheumatoid Arthritis rheumatoid arthritis 6,580,837
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004818/ScoringFiles/PGS004818.txt.gz
PGS004819
(RA_PRSmixPlus_eur)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Rheumatoid Arthritis rheumatoid arthritis 2,624,228
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004819/ScoringFiles/PGS004819.txt.gz
PGS004820
(RA_PRSmixPlus_sas)
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Rheumatoid Arthritis rheumatoid arthritis 6,580,837
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004820/ScoringFiles/PGS004820.txt.gz
PGS004873
(INTERVENE_MegaPRS_RA)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Rheumatoid arthritis rheumatoid arthritis 551,074
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004873/ScoringFiles/PGS004873.txt.gz
PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Hip osteoarthritis osteoarthritis, hip 773,587
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004882/ScoringFiles/PGS004882.txt.gz
PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Knee osteoarthritis osteoarthritis, knee 952,133
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004883/ScoringFiles/PGS004883.txt.gz
PGS018416
(PRS_knee)
 PGP000833 |
Wei Y et al. Clin Nutr (2024)
 Knee osteoarthritis osteoarthritis, knee 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018416/ScoringFiles/PGS018416.txt.gz
PGS018417
(PRS_hip)
 PGP000833 |
Wei Y et al. Clin Nutr (2024)
 Hip osteoarthritis osteoarthritis, hip 70
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018417/ScoringFiles/PGS018417.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000262 PGS000114
(GRS-JIA-20)
 PSS000179|
European Ancestry|
3,513 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Juvenile Idiopathic Arthritis OR: 1.838 [1.686, 2.007] AUROC: 0.735 [0.712, 0.758] — sex, genetic PCs 1-10 —
PPM000263 PGS000114
(GRS-JIA-20)
 PSS000180|
European Ancestry|
940 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Juvenile Idiopathic Arthritis OR: 2.085 [1.773, 2.471] AUROC: 0.738 [0.705, 0.77] — sex, genetic PCs 1-10 —
PPM000260 PGS000114
(GRS-JIA-20)
 PSS000179|
European Ancestry|
3,513 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Juvenile Idiopathic Arthritis OR: 1.831 [1.685, 1.991] AUROC: 0.657 [0.631, 0.683] — — —
PPM000261 PGS000114
(GRS-JIA-20)
 PSS000180|
European Ancestry|
940 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Juvenile Idiopathic Arthritis OR: 2.008 [1.731, 2.345] AUROC: 0.671 [0.635, 0.706] — — —
PPM000577 PGS000194
(G-PROB_Rapos)
 PSS000315|
European Ancestry|
243 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis — AUROC: 0.69 [0.63, 0.76] — RAN_Gprob (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit)
PPM000571 PGS000194
(G-PROB_Rapos)
 PSS000314|
European Ancestry|
245 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis — AUROC: 0.75 [0.68, 0.81] — G-PROB_Raneg (Setting II: Assigning patient diagnoses based on medical records)
PPM000565 PGS000194
(G-PROB_Rapos)
 PSS000322|
Multi-ancestry (including European)|
1,211 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis — AUROC: 0.69 [0.65, 0.72] — G-PROB_Raneg (Setting I: Assigning patient diagnoses based on billing codes)
PPM000578 PGS000195
(G-PROB_Raneg)
 PSS000315|
European Ancestry|
243 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis — AUROC: 0.69 [0.63, 0.76] — G-PROB_Rapos (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit)
PPM000572 PGS000195
(G-PROB_Raneg)
 PSS000314|
European Ancestry|
245 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis — AUROC: 0.75 [0.68, 0.81] — G-PROB_Rapos (Setting II: Assigning patient diagnoses based on medical records)
PPM000566 PGS000195
(G-PROB_Raneg)
 PSS000322|
Multi-ancestry (including European)|
1,211 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis — AUROC: 0.69 [0.65, 0.72] — G-PROB_Rapos (Setting I: Assigning patient diagnoses based on billing codes)
PPM000580 PGS000197
(G-PROB_SpA)
 PSS000317|
European Ancestry|
243 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Spondyloarthropathy diagnosis in patient with arthritis — AUROC: 0.56 [0.33, 0.84] — — (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit)
PPM000574 PGS000197
(G-PROB_SpA)
 PSS000316|
European Ancestry|
245 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Spondyloarthropathy diagnosis in patient with arthritis — AUROC: 0.87 [0.76, 0.96] — — (Setting II: Assigning patient diagnoses based on medical records)
PPM000568 PGS000197
(G-PROB_SpA)
 PSS000323|
Multi-ancestry (including European)|
1,211 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Spondyloarthropathy diagnosis in patient with arthritis — AUROC: 0.58 [0.5, 0.67] — — (Setting I: Assigning patient diagnoses based on billing codes)
PPM000581 PGS000198
(G-PROB_PsA)
 PSS000313|
European Ancestry|
243 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis — AUROC: 0.62 [0.48, 0.8] — — (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit)
PPM000575 PGS000198
(G-PROB_PsA)
 PSS000312|
European Ancestry|
245 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis — AUROC: 0.71 [0.63, 0.82] — — (Setting II: Assigning patient diagnoses based on medical records)
PPM000569 PGS000198
(G-PROB_PsA)
 PSS000321|
Multi-ancestry (including European)|
1,211 individuals
 PGP000081 |
Knevel R et al. Sci Transl Med (2020)
 Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis — AUROC: 0.61 [0.52, 0.69] — — (Setting I: Assigning patient diagnoses based on billing codes)
PPM000874 PGS000324
(GRS-JIA-ERA-20)
 PSS000432|
European Ancestry|
594 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Enthesitis-related Arthritis OR: 3.09 [2.07, 5.04] AUROC: 0.93 [0.86, 0.99] — sex, genetic PCs 1-10 —
PPM000873 PGS000324
(GRS-JIA-ERA-20)
 PSS000429|
European Ancestry|
3,020 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Enthesitis-related Arthritis OR: 1.86 [1.61, 2.14] AUROC: 0.75 [0.68, 0.82] — sex, genetic PCs 1-10 —
PPM000867 PGS000324
(GRS-JIA-ERA-20)
 PSS000429|
European Ancestry|
3,020 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Enthesitis-related Arthritis OR: 1.84 [1.6, 2.17] AUROC: 0.7 [0.63, 0.77] — — —
PPM000868 PGS000324
(GRS-JIA-ERA-20)
 PSS000432|
European Ancestry|
594 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Enthesitis-related Arthritis OR: 2.99 [2.11, 4.54] AUROC: 0.84 [0.71, 0.97] — — —
PPM000875 PGS000325
(GRS-JIA-Oli-20)
 PSS000430|
European Ancestry|
3,157 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis OR: 1.93 [1.75, 2.13] AUROC: 0.8 [0.77, 0.84] — sex, genetic PCs 1-10 —
PPM000876 PGS000325
(GRS-JIA-Oli-20)
 PSS000433|
European Ancestry|
737 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis OR: 2.19 [1.81, 2.71] AUROC: 0.79 [0.76, 0.83] — sex, genetic PCs 1-10 —
PPM000869 PGS000325
(GRS-JIA-Oli-20)
 PSS000430|
European Ancestry|
3,157 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis OR: 1.93 [1.76, 2.11] AUROC: 0.77 [0.73, 0.8] — — —
PPM000870 PGS000325
(GRS-JIA-Oli-20)
 PSS000433|
European Ancestry|
737 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis OR: 2.24 [1.88, 2.71] AUROC: 0.74 [0.7, 0.79] — — —
PPM000878 PGS000326
(GRS-JIA-RFN-20)
 PSS000434|
European Ancestry|
653 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Rheumatoid-factor-negative Polyarthritis OR: 1.71 [1.42, 2.07] AUROC: 0.74 [0.68, 0.8] — sex, genetic PCs 1-10 —
PPM000872 PGS000326
(GRS-JIA-RFN-20)
 PSS000434|
European Ancestry|
653 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Rheumatoid-factor-negative Polyarthritis OR: 1.69 [1.42, 2.02] AUROC: 0.66 [0.59, 0.73] — — —
PPM000877 PGS000326
(GRS-JIA-RFN-20)
 PSS000431|
European Ancestry|
3,089 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Rheumatoid-factor-negative Polyarthritis OR: 1.51 [1.35, 1.68] AUROC: 0.76 [0.72, 0.8] — sex, genetic PCs 1-10 —
PPM000871 PGS000326
(GRS-JIA-RFN-20)
 PSS000431|
European Ancestry|
3,089 individuals
 PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
 Reported Trait: Rheumatoid-factor-negative Polyarthritis OR: 1.48 [1.33, 1.64] AUROC: 0.64 [0.59, 0.69] — — —
PPM000971 PGS000342
(wGRS_PsA)
 PSS000490|
Ancestry Not Reported|
543 individuals
 PGP000111 |
Smith MP et al. J Psoriasis Psoriatic Arthritis (2020)
 Reported Trait: Psoriatic arthritis — AUROC: 0.562 [0.506, 0.618] — — —
PPM000972 PGS000343
(wGRS_PsA_HLA)
 PSS000490|
Ancestry Not Reported|
543 individuals
 PGP000111 |
Smith MP et al. J Psoriasis Psoriatic Arthritis (2020)
 Reported Trait: Psoriatic arthritis — AUROC: 0.569 [0.513, 0.625] — — —
PPM007658 PGS000967
(GBE_HC1221)
 PSS004208|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE coxarthrosis [arthrosis of hip] — AUROC: 0.63448 [0.57611, 0.69284] R²: 0.02258
Incremental AUROC (full-covars): 0.01789
PGS R2 (no covariates): 0.0065
PGS AUROC (no covariates): 0.57452 [0.51022, 0.63883]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007659 PGS000967
(GBE_HC1221)
 PSS004209|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE coxarthrosis [arthrosis of hip] — AUROC: 0.67991 [0.52221, 0.83761] R²: 0.03974
Incremental AUROC (full-covars): 0.00141
PGS R2 (no covariates): 0.00044
PGS AUROC (no covariates): 0.52299 [0.39821, 0.64778]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007660 PGS000967
(GBE_HC1221)
 PSS004210|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE coxarthrosis [arthrosis of hip] — AUROC: 0.71352 [0.69682, 0.73022] R²: 0.07227
Incremental AUROC (full-covars): 0.00368
PGS R2 (no covariates): 0.00258
PGS AUROC (no covariates): 0.54164 [0.52116, 0.56213]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007661 PGS000967
(GBE_HC1221)
 PSS004211|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE coxarthrosis [arthrosis of hip] — AUROC: 0.72467 [0.66733, 0.78201] R²: 0.06598
Incremental AUROC (full-covars): -0.00237
PGS R2 (no covariates): 1e-05
PGS AUROC (no covariates): 0.50363 [0.44232, 0.56493]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007662 PGS000967
(GBE_HC1221)
 PSS004212|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE coxarthrosis [arthrosis of hip] — AUROC: 0.69051 [0.68108, 0.69995] R²: 0.06247
Incremental AUROC (full-covars): 0.00918
PGS R2 (no covariates): 0.00628
PGS AUROC (no covariates): 0.5611 [0.55051, 0.57168]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008289 PGS001110
(GBE_HC1209)
 PSS004183|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE reactive arthropathies — AUROC: 0.9594 [0.92062, 0.99818] R²: 0.17918
Incremental AUROC (full-covars): 0.00395
PGS R2 (no covariates): 0.00991
PGS AUROC (no covariates): 0.72061 [0.49213, 0.9491]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008290 PGS001110
(GBE_HC1209)
 PSS004185|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE reactive arthropathies — AUROC: 0.77096 [0.63921, 0.90271] R²: 0.09743
Incremental AUROC (full-covars): 0.03274
PGS R2 (no covariates): 0.03411
PGS AUROC (no covariates): 0.65137 [0.47674, 0.826]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008291 PGS001110
(GBE_HC1209)
 PSS004186|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE reactive arthropathies — AUROC: 0.94552 [0.83969, 1.0] R²: 0.25627
Incremental AUROC (full-covars): 0.00045
PGS R2 (no covariates): 0.00071
PGS AUROC (no covariates): 0.67786 [0.66768, 0.68805]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008292 PGS001110
(GBE_HC1209)
 PSS004187|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE reactive arthropathies — AUROC: 0.6839 [0.58647, 0.78132] R²: 0.03053
Incremental AUROC (full-covars): 0.07922
PGS R2 (no covariates): 0.02879
PGS AUROC (no covariates): 0.66167 [0.54859, 0.77475]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008403 PGS001135
(GBE_HC78)
 PSS004627|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arthritis (nos) — AUROC: 0.7166 [0.69191, 0.7413] R²: 0.0961
Incremental AUROC (full-covars): -0.00204
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.50267 [0.47421, 0.53114]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008404 PGS001135
(GBE_HC78)
 PSS004628|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arthritis (nos) — AUROC: 0.78855 [0.73521, 0.8419] R²: 0.13042
Incremental AUROC (full-covars): -0.00593
PGS R2 (no covariates): 0.00821
PGS AUROC (no covariates): 0.42483 [0.32454, 0.52511]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008405 PGS001135
(GBE_HC78)
 PSS004629|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arthritis (nos) — AUROC: 0.67424 [0.65969, 0.68878] R²: 0.05468
Incremental AUROC (full-covars): 0.00314
PGS R2 (no covariates): 0.00291
PGS AUROC (no covariates): 0.53928 [0.52302, 0.55554]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008406 PGS001135
(GBE_HC78)
 PSS004630|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arthritis (nos) — AUROC: 0.71014 [0.68888, 0.73139] R²: 0.08893
Incremental AUROC (full-covars): 0.00207
PGS R2 (no covariates): 0.00153
PGS AUROC (no covariates): 0.52639 [0.5015, 0.55128]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008407 PGS001135
(GBE_HC78)
 PSS004631|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Arthritis (nos) — AUROC: 0.64961 [0.64135, 0.65786] R²: 0.04342
Incremental AUROC (full-covars): 0.00228
PGS R2 (no covariates): 0.00147
PGS AUROC (no covariates): 0.52671 [0.51771, 0.53571]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008609 PGS001192
(GBE_HC1222)
 PSS004213|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE gonarthrosis [arthrosis of knee] — AUROC: 0.68497 [0.65949, 0.71044] R²: 0.07256
Incremental AUROC (full-covars): -0.01106
PGS R2 (no covariates): 0.00014
PGS AUROC (no covariates): 0.48548 [0.45782, 0.51313]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008610 PGS001192
(GBE_HC1222)
 PSS004214|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE gonarthrosis [arthrosis of knee] — AUROC: 0.6973 [0.62907, 0.76552] R²: 0.05404
Incremental AUROC (full-covars): -0.01876
PGS R2 (no covariates): 0.00104
PGS AUROC (no covariates): 0.48101 [0.40847, 0.55354]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008611 PGS001192
(GBE_HC1222)
 PSS004215|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE gonarthrosis [arthrosis of knee] — AUROC: 0.66024 [0.6461, 0.67438] PGS R2 (no covariates): 0.00516
R²: 0.04745
Incremental AUROC (full-covars): 0.00488
PGS AUROC (no covariates): 0.54777 [0.53172, 0.56382]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008612 PGS001192
(GBE_HC1222)
 PSS004216|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE gonarthrosis [arthrosis of knee] — AUROC: 0.72749 [0.70853, 0.74646] R²: 0.11678
Incremental AUROC (full-covars): 0.00024
PGS R2 (no covariates): 0.00229
PGS AUROC (no covariates): 0.53307 [0.5103, 0.55585]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008613 PGS001192
(GBE_HC1222)
 PSS004217|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE gonarthrosis [arthrosis of knee] — AUROC: 0.64504 [0.63733, 0.65274] R²: 0.04312
Incremental AUROC (full-covars): 0.0104
PGS R2 (no covariates): 0.0068
PGS AUROC (no covariates): 0.55655 [0.54824, 0.56485]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008840 PGS001267
(GBE_HC422)
 PSS004486|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.86744 [0.75569, 0.97918] R²: 0.1463
Incremental AUROC (full-covars): -0.00062
PGS R2 (no covariates): 0.00216
PGS AUROC (no covariates): 0.4722 [0.12421, 0.82018]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008841 PGS001267
(GBE_HC422)
 PSS004487|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.98913 [0.972, 1.0] R²: 0.44316
Incremental AUROC (full-covars): 0.0423
PGS R2 (no covariates): 0.24382
PGS AUROC (no covariates): 0.81698 [0.46329, 1.0]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008842 PGS001267
(GBE_HC422)
 PSS004488|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.73638 [0.67151, 0.80124] R²: 0.10414
Incremental AUROC (full-covars): 0.06004
PGS R2 (no covariates): 0.07222
PGS AUROC (no covariates): 0.67545 [0.60736, 0.74353]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008843 PGS001267
(GBE_HC422)
 PSS004489|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.73535 [0.61203, 0.85867] R²: 0.03713
Incremental AUROC (full-covars): -0.01782
PGS R2 (no covariates): 0.00902
PGS AUROC (no covariates): 0.42181 [0.29024, 0.55338]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008844 PGS001267
(GBE_HC422)
 PSS004490|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.74328 [0.70673, 0.77983] R²: 0.10925
Incremental AUROC (full-covars): 0.12994
PGS R2 (no covariates): 0.09877
PGS AUROC (no covariates): 0.72651 [0.68965, 0.76337]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008845 PGS001268
(GBE_HC1242)
 PSS004228|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ankylosing spondylitis — AUROC: 0.86811 [0.75774, 0.97849] R²: 0.14598
Incremental AUROC (full-covars): 6e-05
PGS R2 (no covariates): 0.00104
PGS AUROC (no covariates): 0.48424 [0.12443, 0.84406]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008846 PGS001268
(GBE_HC1242)
 PSS004229|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ankylosing spondylitis — AUROC: 0.99148 [0.9789, 1.0] R²: 0.44858
Incremental AUROC (full-covars): 0.04465
PGS R2 (no covariates): 0.23755
PGS AUROC (no covariates): 0.81257 [0.45025, 1.0]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008847 PGS001268
(GBE_HC1242)
 PSS004230|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ankylosing spondylitis — AUROC: 0.73336 [0.66901, 0.79772] R²: 0.10217
Incremental AUROC (full-covars): 0.0575
PGS R2 (no covariates): 0.06991
PGS AUROC (no covariates): 0.67405 [0.607, 0.74111]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008848 PGS001268
(GBE_HC1242)
 PSS004231|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ankylosing spondylitis — AUROC: 0.73282 [0.61573, 0.84991] R²: 0.03979
Incremental AUROC (full-covars): -0.01963
PGS R2 (no covariates): 0.00774
PGS AUROC (no covariates): 0.4297 [0.29438, 0.56502]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008849 PGS001268
(GBE_HC1242)
 PSS004232|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE ankylosing spondylitis — AUROC: 0.74878 [0.71314, 0.78442] R²: 0.115
Incremental AUROC (full-covars): 0.12686
PGS R2 (no covariates): 0.10232
PGS AUROC (no covariates): 0.7346 [0.69884, 0.77037]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008933 PGS001287
(GBE_HC91)
 PSS004706|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriatic arthropathy — AUROC: 0.98006 [0.94602, 1.0] Incremental AUROC (full-covars): 0.00516
R²: 0.29301
PGS R2 (no covariates): 0.01017
PGS AUROC (no covariates): 0.72132 [0.63231, 0.81034]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008934 PGS001287
(GBE_HC91)
 PSS004707|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriatic arthropathy — AUROC: 0.99354 [0.98059, 1.0] R²: 0.5357
Incremental AUROC (full-covars): -0.00088
PGS R2 (no covariates): 0.00227
PGS AUROC (no covariates): 0.47826 [0.0, 0.96911]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008935 PGS001287
(GBE_HC91)
 PSS004708|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriatic arthropathy — AUROC: 0.72814 [0.67154, 0.78475] R²: 0.05154
Incremental AUROC (full-covars): 0.08346
PGS R2 (no covariates): 0.0335
PGS AUROC (no covariates): 0.67648 [0.61155, 0.7414]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008936 PGS001287
(GBE_HC91)
 PSS004709|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriatic arthropathy — AUROC: 0.71827 [0.61363, 0.82292] R²: 0.04395
Incremental AUROC (full-covars): 0.00838
PGS R2 (no covariates): 0.00229
PGS AUROC (no covariates): 0.56943 [0.44876, 0.69011]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008937 PGS001287
(GBE_HC91)
 PSS004710|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Psoriatic arthropathy — AUROC: 0.6376 [0.60073, 0.67447] R²: 0.02161
Incremental AUROC (full-covars): 0.0945
PGS R2 (no covariates): 0.02111
PGS AUROC (no covariates): 0.63567 [0.598, 0.67334]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008948 PGS001290
(GBE_HC376)
 PSS004461|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Osteoarthritis — AUROC: 0.75416 [0.72668, 0.78163] R²: 0.12216
Incremental AUROC (full-covars): -3e-05
PGS R2 (no covariates): 0.00052
PGS AUROC (no covariates): 0.51951 [0.48655, 0.55248]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008949 PGS001290
(GBE_HC376)
 PSS004462|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Osteoarthritis — AUROC: 0.74181 [0.68024, 0.80338] R²: 0.09715
Incremental AUROC (full-covars): -0.00139
PGS R2 (no covariates): 0.00189
PGS AUROC (no covariates): 0.54245 [0.47153, 0.61338]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008950 PGS001290
(GBE_HC376)
 PSS004463|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Osteoarthritis — AUROC: 0.70244 [0.69044, 0.71444] R²: 0.08191
Incremental AUROC (full-covars): 0.0007
PGS R2 (no covariates): 0.0006
PGS AUROC (no covariates): 0.51661 [0.5024, 0.53082]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008951 PGS001290
(GBE_HC376)
 PSS004464|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Osteoarthritis — AUROC: 0.72534 [0.70181, 0.74887] R²: 0.09768
Incremental AUROC (full-covars): -0.00173
PGS R2 (no covariates): 1e-05
PGS AUROC (no covariates): 0.49787 [0.47035, 0.52539]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008952 PGS001290
(GBE_HC376)
 PSS004465|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Osteoarthritis — AUROC: 0.67419 [0.66753, 0.68085] R²: 0.0674
Incremental AUROC (full-covars): 0.00134
PGS R2 (no covariates): 0.00109
PGS AUROC (no covariates): 0.52166 [0.51404, 0.52927]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009039 PGS001309
(GBE_HC1212)
 PSS004193|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other rheumatoid arthritis — AUROC: 0.69751 [0.65515, 0.73988] R²: 0.05129
Incremental AUROC (full-covars): -0.00017
PGS R2 (no covariates): 0.00056
PGS AUROC (no covariates): 0.52591 [0.47486, 0.57696]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009040 PGS001309
(GBE_HC1212)
 PSS004194|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other rheumatoid arthritis — AUROC: 0.67331 [0.56418, 0.78244] R²: 0.07058
Incremental AUROC (full-covars): -0.02511
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.50714 [0.3797, 0.63457]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009041 PGS001309
(GBE_HC1212)
 PSS004195|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other rheumatoid arthritis — AUROC: 0.6872 [0.66167, 0.71273] R²: 0.04826
Incremental AUROC (full-covars): 0.02601
PGS R2 (no covariates): 0.01537
PGS AUROC (no covariates): 0.59782 [0.56885, 0.62679]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009042 PGS001309
(GBE_HC1212)
 PSS004196|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other rheumatoid arthritis — AUROC: 0.70239 [0.66722, 0.73755] R²: 0.06164
Incremental AUROC (full-covars): -0.00362
PGS R2 (no covariates): 0.00158
PGS AUROC (no covariates): 0.53481 [0.4923, 0.57731]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009043 PGS001309
(GBE_HC1212)
 PSS004197|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE other rheumatoid arthritis — AUROC: 0.66538 [0.65101, 0.67976] R²: 0.03893
Incremental AUROC (full-covars): 0.03207
PGS R2 (no covariates): 0.01495
PGS AUROC (no covariates): 0.59784 [0.582, 0.61368]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009044 PGS001310
(GBE_HC430)
 PSS004491|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.70522 [0.66309, 0.74736] R²: 0.0544
Incremental AUROC (full-covars): 0.00203
PGS R2 (no covariates): 0.00109
PGS AUROC (no covariates): 0.53147 [0.47999, 0.58294]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009045 PGS001310
(GBE_HC430)
 PSS004492|
East Asian Ancestry|
1,704 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.66116 [0.54578, 0.77655] R²: 0.06929
Incremental AUROC (full-covars): -0.02514
PGS R2 (no covariates): 0.00033
PGS AUROC (no covariates): 0.52178 [0.38366, 0.6599]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009046 PGS001310
(GBE_HC430)
 PSS004493|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.68857 [0.6632, 0.71393] R²: 0.04919
Incremental AUROC (full-covars): 0.02092
PGS R2 (no covariates): 0.01316
PGS AUROC (no covariates): 0.58714 [0.55751, 0.61676]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009047 PGS001310
(GBE_HC430)
 PSS004494|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.70402 [0.66905, 0.73899] R²: 0.06207
Incremental AUROC (full-covars): -0.0019
PGS R2 (no covariates): 0.00142
PGS AUROC (no covariates): 0.53137 [0.48984, 0.57291]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009048 PGS001310
(GBE_HC430)
 PSS004495|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.66508 [0.65049, 0.67967] R²: 0.03894
Incremental AUROC (full-covars): 0.03077
PGS R2 (no covariates): 0.01509
PGS AUROC (no covariates): 0.60018 [0.58428, 0.61607]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009049 PGS001311
(GBE_HC1211)
 PSS004188|
African Ancestry|
6,497 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE seropositive rheumatoid arthritis — AUROC: 0.90345 [0.82233, 0.98457] R²: 0.16794
Incremental AUROC (full-covars): -0.00669
PGS R2 (no covariates): 0.01613
PGS AUROC (no covariates): 0.39273 [0.11505, 0.67041]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009050 PGS001311
(GBE_HC1211)
 PSS004190|
European Ancestry|
24,905 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE seropositive rheumatoid arthritis — AUROC: 0.76787 [0.6839, 0.85184] R²: 0.08412
Incremental AUROC (full-covars): 0.0418
PGS R2 (no covariates): 0.05847
PGS AUROC (no covariates): 0.73164 [0.63667, 0.82662]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009051 PGS001311
(GBE_HC1211)
 PSS004191|
South Asian Ancestry|
7,831 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE seropositive rheumatoid arthritis — AUROC: 0.76865 [0.6608, 0.87651] R²: 0.08089
Incremental AUROC (full-covars): -0.00731
PGS R2 (no covariates): 0.00567
PGS AUROC (no covariates): 0.50626 [0.35145, 0.66107]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009052 PGS001311
(GBE_HC1211)
 PSS004192|
European Ancestry|
67,425 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: TTE seropositive rheumatoid arthritis — AUROC: 0.73785 [0.69634, 0.77936] R²: 0.05309
Incremental AUROC (full-covars): 0.09202
PGS R2 (no covariates): 0.04612
PGS AUROC (no covariates): 0.7072 [0.65945, 0.75495]		 age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009888 PGS001875
(portability-PLR_714.1)
 PSS009352|
European Ancestry|
18,393 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0416 [0.0272, 0.056] sex, age, birth date, deprivation index, 16 PCs —
PPM009889 PGS001875
(portability-PLR_714.1)
 PSS009126|
European Ancestry|
3,878 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0554 [0.0239, 0.0868] sex, age, birth date, deprivation index, 16 PCs —
PPM009890 PGS001875
(portability-PLR_714.1)
 PSS008680|
European Ancestry|
6,241 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0322 [0.0073, 0.057] sex, age, birth date, deprivation index, 16 PCs —
PPM009891 PGS001875
(portability-PLR_714.1)
 PSS008454|
Greater Middle Eastern Ancestry|
1,128 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0363 [-0.0226, 0.095] sex, age, birth date, deprivation index, 16 PCs —
PPM009892 PGS001875
(portability-PLR_714.1)
 PSS008234|
South Asian Ancestry|
5,728 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0097 [-0.0163, 0.0356] sex, age, birth date, deprivation index, 16 PCs —
PPM009893 PGS001875
(portability-PLR_714.1)
 PSS008014|
East Asian Ancestry|
1,754 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0277 [-0.0194, 0.0746] sex, age, birth date, deprivation index, 16 PCs —
PPM009894 PGS001875
(portability-PLR_714.1)
 PSS007799|
African Ancestry|
2,277 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): -0.0138 [-0.055, 0.0275] sex, age, birth date, deprivation index, 16 PCs —
PPM009895 PGS001875
(portability-PLR_714.1)
 PSS008903|
African Ancestry|
3,634 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): -0.0251 [-0.0577, 0.0075] sex, age, birth date, deprivation index, 16 PCs —
PPM009896 PGS001876
(portability-PLR_715.2)
 PSS009353|
European Ancestry|
18,262 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.0797 [0.0653, 0.0941] sex, age, birth date, deprivation index, 16 PCs —
PPM009897 PGS001876
(portability-PLR_715.2)
 PSS009127|
European Ancestry|
3,854 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.0453 [0.0137, 0.0769] sex, age, birth date, deprivation index, 16 PCs —
PPM009898 PGS001876
(portability-PLR_715.2)
 PSS008681|
European Ancestry|
6,216 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.0521 [0.0272, 0.0769] sex, age, birth date, deprivation index, 16 PCs —
PPM009899 PGS001876
(portability-PLR_715.2)
 PSS008455|
Greater Middle Eastern Ancestry|
1,124 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.1472 [0.0889, 0.2044] sex, age, birth date, deprivation index, 16 PCs —
PPM009900 PGS001876
(portability-PLR_715.2)
 PSS008235|
South Asian Ancestry|
5,671 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.0279 [0.0019, 0.054] sex, age, birth date, deprivation index, 16 PCs —
PPM009917 PGS001879
(portability-PLR_727.4)
 PSS009356|
European Ancestry|
18,953 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ganglion and cyst of synovium, tendon, and bursa — — Partial Correlation (partial-r): 0.0188 [0.0046, 0.033] sex, age, birth date, deprivation index, 16 PCs —
PPM009918 PGS001879
(portability-PLR_727.4)
 PSS009130|
European Ancestry|
3,909 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ganglion and cyst of synovium, tendon, and bursa — — Partial Correlation (partial-r): -0.0022 [-0.0337, 0.0292] sex, age, birth date, deprivation index, 16 PCs —
PPM009919 PGS001879
(portability-PLR_727.4)
 PSS008684|
European Ancestry|
6,366 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ganglion and cyst of synovium, tendon, and bursa — — Partial Correlation (partial-r): -0.0003 [-0.0249, 0.0243] sex, age, birth date, deprivation index, 16 PCs —
PPM009920 PGS001879
(portability-PLR_727.4)
 PSS008458|
Greater Middle Eastern Ancestry|
1,137 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ganglion and cyst of synovium, tendon, and bursa — — Partial Correlation (partial-r): -0.0036 [-0.0623, 0.0551] sex, age, birth date, deprivation index, 16 PCs —
PPM009921 PGS001879
(portability-PLR_727.4)
 PSS008238|
South Asian Ancestry|
5,964 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ganglion and cyst of synovium, tendon, and bursa — — Partial Correlation (partial-r): 0.0056 [-0.0198, 0.031] sex, age, birth date, deprivation index, 16 PCs —
PPM009922 PGS001879
(portability-PLR_727.4)
 PSS008017|
East Asian Ancestry|
1,759 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ganglion and cyst of synovium, tendon, and bursa — — Partial Correlation (partial-r): -0.0128 [-0.0598, 0.0342] sex, age, birth date, deprivation index, 16 PCs —
PPM009923 PGS001879
(portability-PLR_727.4)
 PSS007802|
African Ancestry|
2,358 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ganglion and cyst of synovium, tendon, and bursa — — Partial Correlation (partial-r): -0.0261 [-0.0666, 0.0144] sex, age, birth date, deprivation index, 16 PCs —
PPM009924 PGS001879
(portability-PLR_727.4)
 PSS008906|
African Ancestry|
3,779 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ganglion and cyst of synovium, tendon, and bursa — — Partial Correlation (partial-r): 0.0184 [-0.0135, 0.0504] sex, age, birth date, deprivation index, 16 PCs —
PPM009940 PGS001882
(portability-PLR_740)
 PSS009359|
European Ancestry|
20,000 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0409 [0.027, 0.0547] sex, age, birth date, deprivation index, 16 PCs —
PPM009941 PGS001882
(portability-PLR_740)
 PSS009133|
European Ancestry|
4,136 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0415 [0.0109, 0.0719] sex, age, birth date, deprivation index, 16 PCs —
PPM009942 PGS001882
(portability-PLR_740)
 PSS008687|
European Ancestry|
6,660 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0357 [0.0117, 0.0597] sex, age, birth date, deprivation index, 16 PCs —
PPM009943 PGS001882
(portability-PLR_740)
 PSS008461|
Greater Middle Eastern Ancestry|
1,200 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0326 [-0.0246, 0.0895] sex, age, birth date, deprivation index, 16 PCs —
PPM009944 PGS001882
(portability-PLR_740)
 PSS008241|
South Asian Ancestry|
6,331 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0211 [-0.0036, 0.0457] sex, age, birth date, deprivation index, 16 PCs —
PPM009945 PGS001882
(portability-PLR_740)
 PSS008019|
East Asian Ancestry|
1,810 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0051 [-0.0412, 0.0514] sex, age, birth date, deprivation index, 16 PCs —
PPM009946 PGS001882
(portability-PLR_740)
 PSS007805|
African Ancestry|
2,484 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0312 [-0.0083, 0.0706] sex, age, birth date, deprivation index, 16 PCs —
PPM009947 PGS001882
(portability-PLR_740)
 PSS008909|
African Ancestry|
3,924 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0103 [-0.0211, 0.0417] sex, age, birth date, deprivation index, 16 PCs —
PPM011564 PGS002088
(portability-ldpred2_714.1)
 PSS009352|
European Ancestry|
18,393 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0434 [0.029, 0.0578] sex, age, birth date, deprivation index, 16 PCs —
PPM011565 PGS002088
(portability-ldpred2_714.1)
 PSS009126|
European Ancestry|
3,878 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0532 [0.0217, 0.0846] sex, age, birth date, deprivation index, 16 PCs —
PPM011566 PGS002088
(portability-ldpred2_714.1)
 PSS008680|
European Ancestry|
6,241 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0284 [0.0036, 0.0532] sex, age, birth date, deprivation index, 16 PCs —
PPM011568 PGS002088
(portability-ldpred2_714.1)
 PSS008234|
South Asian Ancestry|
5,728 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0135 [-0.0125, 0.0394] sex, age, birth date, deprivation index, 16 PCs —
PPM011569 PGS002088
(portability-ldpred2_714.1)
 PSS008014|
East Asian Ancestry|
1,754 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0226 [-0.0245, 0.0696] sex, age, birth date, deprivation index, 16 PCs —
PPM011570 PGS002088
(portability-ldpred2_714.1)
 PSS007799|
African Ancestry|
2,277 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): -0.0007 [-0.0419, 0.0406] sex, age, birth date, deprivation index, 16 PCs —
PPM011571 PGS002088
(portability-ldpred2_714.1)
 PSS008903|
African Ancestry|
3,634 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): -0.0214 [-0.054, 0.0112] sex, age, birth date, deprivation index, 16 PCs —
PPM011567 PGS002088
(portability-ldpred2_714.1)
 PSS008454|
Greater Middle Eastern Ancestry|
1,128 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Rheumatoid arthritis — — Partial Correlation (partial-r): 0.0403 [-0.0186, 0.099] sex, age, birth date, deprivation index, 16 PCs —
PPM011572 PGS002089
(portability-ldpred2_715.2)
 PSS009353|
European Ancestry|
18,262 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.0919 [0.0775, 0.1063] sex, age, birth date, deprivation index, 16 PCs —
PPM011573 PGS002089
(portability-ldpred2_715.2)
 PSS009127|
European Ancestry|
3,854 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.0476 [0.016, 0.0791] sex, age, birth date, deprivation index, 16 PCs —
PPM011574 PGS002089
(portability-ldpred2_715.2)
 PSS008681|
European Ancestry|
6,216 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.0596 [0.0348, 0.0844] sex, age, birth date, deprivation index, 16 PCs —
PPM011576 PGS002089
(portability-ldpred2_715.2)
 PSS008235|
South Asian Ancestry|
5,671 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.0424 [0.0163, 0.0684] sex, age, birth date, deprivation index, 16 PCs —
PPM011575 PGS002089
(portability-ldpred2_715.2)
 PSS008455|
Greater Middle Eastern Ancestry|
1,124 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Ankylosing spondylitis — — Partial Correlation (partial-r): 0.1631 [0.1051, 0.22] sex, age, birth date, deprivation index, 16 PCs —
PPM011608 PGS002094
(portability-ldpred2_740)
 PSS009359|
European Ancestry|
20,000 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0535 [0.0397, 0.0673] sex, age, birth date, deprivation index, 16 PCs —
PPM011609 PGS002094
(portability-ldpred2_740)
 PSS009133|
European Ancestry|
4,136 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0612 [0.0307, 0.0916] sex, age, birth date, deprivation index, 16 PCs —
PPM011610 PGS002094
(portability-ldpred2_740)
 PSS008687|
European Ancestry|
6,660 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0544 [0.0304, 0.0783] sex, age, birth date, deprivation index, 16 PCs —
PPM011611 PGS002094
(portability-ldpred2_740)
 PSS008461|
Greater Middle Eastern Ancestry|
1,200 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.025 [-0.0321, 0.082] sex, age, birth date, deprivation index, 16 PCs —
PPM011612 PGS002094
(portability-ldpred2_740)
 PSS008241|
South Asian Ancestry|
6,331 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0394 [0.0148, 0.064] sex, age, birth date, deprivation index, 16 PCs —
PPM011613 PGS002094
(portability-ldpred2_740)
 PSS008019|
East Asian Ancestry|
1,810 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): -0.0056 [-0.052, 0.0407] sex, age, birth date, deprivation index, 16 PCs —
PPM011614 PGS002094
(portability-ldpred2_740)
 PSS007805|
African Ancestry|
2,484 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.0412 [0.0017, 0.0806] sex, age, birth date, deprivation index, 16 PCs —
PPM011615 PGS002094
(portability-ldpred2_740)
 PSS008909|
African Ancestry|
3,924 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Osteoarthrosis — — Partial Correlation (partial-r): 0.022 [-0.0094, 0.0534] sex, age, birth date, deprivation index, 16 PCs —
PPM012870 PGS002260
(PRS_RA)
 PSS009586|
East Asian Ancestry|
740 individuals
 PGP000286 |
Honda S et al. Arthritis Rheumatol (2022)
 Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis — — OR (top vs 2nd quintile): 1.87 [1.11, 3.15] — —
PPM012871 PGS002260
(PRS_RA)
 PSS009586|
East Asian Ancestry|
740 individuals
 PGP000286 |
Honda S et al. Arthritis Rheumatol (2022)
 Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis (age of onset <40 years) — — OR (top vs 2nd quintile): 6.29 [1.85, 21.4] — —
PPM012872 PGS002260
(PRS_RA)
 PSS009586|
East Asian Ancestry|
740 individuals
 PGP000286 |
Honda S et al. Arthritis Rheumatol (2022)
 Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis OR: 1.3 [1.13, 1.5] — — Age of onset, sex, ever-smoker, ACPAs positivity, rheumatoid factor positivity, BMI, periodontitis, use of methotrexate, use of bDMARD, HLA-DRB1 (Ser11) —
PPM014781 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident severe radiographic osteoarthritis OR: 1.33 [1.12, 1.59] — — — —
PPM014756 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Prevalent radiographic osteoarthritis OR: 1.19 [1.1, 1.28] — — — —
PPM014757 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident radiographic osteoarthritis OR: 1.15 [1.05, 1.26] — — — —
PPM014758 PGS002728
(PRS_hip)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Prevalent radiographic osteoarthritis OR: 1.28 [0.98, 1.65] — — — —
PPM014759 PGS002728
(PRS_hip)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident radiographic osteoarthritis OR: 0.95 [0.82, 1.11] — — — —
PPM014766 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Prevalent clinical osteoarthritis OR: 1.3 [1.15, 1.46] — — — —
PPM014767 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident clinical osteoarthritis OR: 1.22 [0.98, 1.51] — — — —
PPM014768 PGS002728
(PRS_hip)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident clinical osteoarthritis OR: 0.92 [0.74, 1.14] — — — —
PPM014773 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Prevalent total hip replacement OR: 1.26 [1.12, 1.41] — — — —
PPM014774 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident total hip replacement OR: 1.28 [1.11, 1.48] — — — —
PPM014775 PGS002728
(PRS_hip)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident total hip replacement OR: 1.09 [0.79, 1.47] — — — —
PPM014779 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Radiographic osteoarthritis progression OR: 1.18 [1.09, 1.28] — — — —
PPM014783 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Radiographic osteoarthritis — AUROC: 0.59 [0.56, 0.61] — Age, sex —
PPM014784 PGS002728
(PRS_hip)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Radiographic osteoarthritis — AUROC: 0.62 [0.58, 0.65] — Age, sex —
PPM014785 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Clinical osteoarthritis — AUROC: 0.62 [0.56, 0.68] — Age, sex —
PPM014786 PGS002728
(PRS_hip)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Clinical osteoarthritis — AUROC: 0.53 [0.47, 0.59] — Age, sex —
PPM014787 PGS002728
(PRS_hip)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Total hip replacement — AUROC: 0.66 [0.62, 0.70] — Age, sex —
PPM014788 PGS002728
(PRS_hip)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Total hip replacement — AUROC: 0.64 [0.55, 0.73] — Age, sex —
PPM014760 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Prevalent radiographic osteoarthritis OR: 1.17 [1.1, 1.24] — — — —
PPM014771 PGS002729
(PRS_knee)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident clinical osteoarthritis OR: 1.26 [1.05, 1.52] — — — —
PPM014793 PGS002729
(PRS_knee)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Clinical osteoarthritis — AUROC: 0.6 [0.55, 0.65] — Age, sex, BMI —
PPM014761 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident radiographic osteoarthritis OR: 1.15 [1.06, 1.24] — — — —
PPM014762 PGS002729
(PRS_knee)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Prevalent radiographic osteoarthritis OR: 1.27 [0.96, 1.68] — — — —
PPM014763 PGS002729
(PRS_knee)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident radiographic osteoarthritis OR: 1.09 [0.93, 1.29] — — — —
PPM014764 PGS002729
(PRS_knee)
 PSS009890|
European Ancestry|
407 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Prevalent radiographic osteoarthritis OR: 1.02 [0.69, 1.53] — — — —
PPM014765 PGS002729
(PRS_knee)
 PSS009890|
European Ancestry|
407 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident radiographic osteoarthritis OR: 1.04 [0.75, 1.45] — — — —
PPM014769 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Prevalent clinical osteoarthritis OR: 1.23 [1.12, 1.34] — — — —
PPM014770 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident clinical osteoarthritis OR: 1.13 [0.94, 1.37] — — — —
PPM014772 PGS002729
(PRS_knee)
 PSS009890|
European Ancestry|
407 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident clinical osteoarthritis OR: 1.17 [0.8, 1.73] — — — —
PPM014776 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Prevalent total knee replacement OR: 1.3 [0.99, 1.71] — — — —
PPM014777 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident total knee replacement OR: 1.56 [1.27, 1.91] — — — —
PPM014778 PGS002729
(PRS_knee)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident total knee replacement OR: 1.16 [0.65, 2.17] — — — —
PPM014780 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Radiographic osteoarthritis progression OR: 1.18 [1.11, 1.25] — — — —
PPM014782 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Incident severe radiographic osteoarthritis OR: 1.3 [1.04, 1.63] — — — —
PPM014789 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Radiographic osteoarthritis — AUROC: 0.6 [0.58, 0.63] — Age, sex, BMI —
PPM014790 PGS002729
(PRS_knee)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Radiographic osteoarthritis — AUROC: 0.57 [0.53, 0.62] — Age, sex, BMI —
PPM014791 PGS002729
(PRS_knee)
 PSS009890|
European Ancestry|
407 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Radiographic osteoarthritis — AUROC: 0.53 [0.44, 0.63] — Age, BMI —
PPM014792 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Clinical osteoarthritis — AUROC: 0.66 [0.61, 0.71] — Age, sex, BMI —
PPM014794 PGS002729
(PRS_knee)
 PSS009890|
European Ancestry|
407 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Clinical osteoarthritis — AUROC: 0.52 [0.41, 0.63] — Age, BMI —
PPM014795 PGS002729
(PRS_knee)
 PSS009891|
European Ancestry|
14,926 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Total hip replacement — AUROC: 0.66 [0.61, 0.71] — Age, sex, BMI —
PPM014796 PGS002729
(PRS_knee)
 PSS009889|
European Ancestry|
1,002 individuals
 PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
 Reported Trait: Total hip replacement — AUROC: 0.65 [0.49, 0.82] — Age, sex, BMI —
PPM014915 PGS002745
(metaPGS_RA)
 PSS009927|
Multi-ancestry (including European)|
7,460 individuals
 PGP000357 |
Ishigaki K et al. Nat Genet (2022)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.65 Liability R2: 0.054 Sex, Genotype PCs Performance metrics are the mean values across eave-one-cohort-out cross-validation folds
PPM014916 PGS002745
(metaPGS_RA)
 PSS009930|
European Ancestry|
3,887 individuals
 PGP000357 |
Ishigaki K et al. Nat Genet (2022)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.66 Liability R2: 0.059 Sex, Genotype PCs Performance metrics are the mean values across eave-one-cohort-out cross-validation folds
PPM014917 PGS002745
(metaPGS_RA)
 PSS009929|
East Asian Ancestry|
21,704 individuals
 PGP000357 |
Ishigaki K et al. Nat Genet (2022)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.66 Liability R2: 0.057 Sex, Genotype PCs Performance metrics are the mean values across eave-one-cohort-out cross-validation folds
PPM014918 PGS002745
(metaPGS_RA)
 PSS009928|
Multi-ancestry (excluding European)|
1,304 individuals
 PGP000357 |
Ishigaki K et al. Nat Genet (2022)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.59 Liability R2: 0.018 Sex, Genotype PCs Performance metrics are the mean values across eave-one-cohort-out cross-validation folds
PPM014939 PGS002749
(PRS10_TKR)
 PSS009936|
European Ancestry|
1,422 individuals
 PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
 Reported Trait: Knee replacement OR: 1.13 [1.07, 1.2] — — Age, sex, body mass index, education, and index of relative socioeconomic advantage and disadvantage —
PPM014940 PGS002750
(PRS37_THR)
 PSS009935|
European Ancestry|
1,257 individuals
 PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
 Reported Trait: Hip replacement OR: 1.23 [1.16, 1.3] — — Age, sex, body mass index, education, and index of relative socioeconomic advantage and disadvantage —
PPM014941 PGS002750
(PRS37_THR)
 PSS009935|
European Ancestry|
1,257 individuals
 PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
 Reported Trait: Hip replacement in men OR: 1.15 [1.06, 1.26] — — Age, body mass index, education, and index of relative socioeconomic advantage and disadvantage —
PPM014942 PGS002750
(PRS37_THR)
 PSS009935|
European Ancestry|
1,257 individuals
 PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
 Reported Trait: Hip replacement in women OR: 1.3 [1.2, 1.4] — — Age, body mass index, education, and index of relative socioeconomic advantage and disadvantage —
PPM014963 PGS002763
(Hip_osteoarthritis_prscs)
 PSS009939|
European Ancestry|
39,444 individuals
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Reported Trait: Hip osteoarthritis OR: 1.38 [1.31, 1.46] — — age, sex, 10 PCs, technical covariates —
PPM014967 PGS002767
(Knee_osteoarthritis_prscs)
 PSS009939|
European Ancestry|
39,444 individuals
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Reported Trait: Knee osteoarthritis OR: 1.35 [1.3, 1.4] — — age, sex, 10 PCs, technical covariates —
PPM014969 PGS002769
(Rheumatoid_arthritis_prscs)
 PSS009939|
European Ancestry|
39,444 individuals
 PGP000364 |
Mars N et al. Am J Hum Genet (2022)
 Reported Trait: Seropositive rheumatoid arthritis OR: 1.72 [1.61, 1.83] — — age, sex, 10 PCs, technical covariates —
PPM017073 PGS003420
(PRS100_PRScs)
 PSS010115|
East Asian Ancestry|
1,298 individuals
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.7886 — — —
PPM017074 PGS003421
(PRS16_C+T)
 PSS010115|
East Asian Ancestry|
1,298 individuals
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.7876 — — —
PPM017075 PGS003422
(PRS16_PRSice2)
 PSS010115|
East Asian Ancestry|
1,298 individuals
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.7876 — — —
PPM017076 PGS003423
(PRS100_Lassosum)
 PSS010115|
East Asian Ancestry|
1,298 individuals
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.7754 — — —
PPM017077 PGS003424
(PRS100_LDpred2)
 PSS010115|
East Asian Ancestry|
1,298 individuals
 PGP000431 |
Ko CL et al. J Transl Med (2022)
 Reported Trait: Ankylosing spondylitis — AUROC: 0.7605 — — —
PPM020015 PGS003994
(dbslmm.auto.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.33393 [1.28094638, 1.3890998]
β: 0.28813 [0.24759916, 0.32865591]		 AUROC: 0.58064 [0.56883718, 0.59243732] R²: 0.01224 [0.00905012, 0.0158579] 0 beta = log(or)/sd_pgs
PPM020017 PGS003994
(dbslmm.auto.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.37351 [1.09734382, 1.71919027]
β: 0.31737 [0.09289255, 0.54185341]		 AUROC: 0.57062 [0.49087135, 0.65037199] R²: 0.01113 [0.000312, 0.040902] 0 beta = log(or)/sd_pgs
PPM020018 PGS003994
(dbslmm.auto.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.1176 [1.05475987, 1.18418315]
β: 0.11118 [0.05331313, 0.16905321]		 AUROC: 0.52923 [0.5116339, 0.54683125] R²: 0.0019 [0.000371, 0.00466991] 0 beta = log(or)/sd_pgs
PPM020019 PGS003994
(dbslmm.auto.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.82399 [1.59169421, 2.09018269]
β: 0.60103 [0.46479899, 0.73725147]		 AUROC: 0.65883 [0.61913538, 0.6985174] R²: 0.05369 [0.03020613, 0.08591409] 0 beta = log(or)/sd_pgs
PPM020016 PGS003994
(dbslmm.auto.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.50841 [1.47749798, 1.53996605]
β: 0.41106 [0.3903501, 0.43176037]		 AUROC: 0.61202 [0.60619063, 0.61785875] R²: 0.02501 [0.02245787, 0.02749797] 0 beta = log(or)/sd_pgs
PPM020050 PGS004010
(lassosum.auto.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.32987 [1.28121824, 1.38036919]
β: 0.28508 [0.24781138, 0.32235099]		 AUROC: 0.58517 [0.5735, 0.59683621] R²: 0.01384 [0.01026836, 0.01752212] 0 beta = log(or)/sd_pgs
PPM020051 PGS004010
(lassosum.auto.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.49732 [1.46602685, 1.52927706]
β: 0.40368 [0.38255592, 0.42479511]		 AUROC: 0.60802 [0.60210105, 0.6139434] R²: 0.02326 [0.02088065, 0.0257906] 0 beta = log(or)/sd_pgs
PPM020052 PGS004010
(lassosum.auto.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.28607 [1.08009867, 1.53131211]
β: 0.25159 [0.0770524, 0.42612496]		 AUROC: 0.59832 [0.52394235, 0.67270553] R²: 0.01158 [0.00106957, 0.04053787] 0 beta = log(or)/sd_pgs
PPM020053 PGS004010
(lassosum.auto.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.18691 [1.12316952, 1.25426353]
β: 0.17135 [0.11615461, 0.22654857]		 AUROC: 0.55861 [0.54216624, 0.57505125] R²: 0.00494 [0.00224141, 0.008649] 0 beta = log(or)/sd_pgs
PPM020054 PGS004010
(lassosum.auto.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.59047 [1.42931885, 1.76979456]
β: 0.46403 [0.357198, 0.57086347]		 AUROC: 0.6696 [0.63218416, 0.70702386] R²: 0.05578 [0.03219308, 0.08912121] 0 beta = log(or)/sd_pgs
PPM020055 PGS004021
(lassosum.CV.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.46364 [1.40722648, 1.52232499]
β: 0.38093 [0.34162073, 0.42023876]		 AUROC: 0.60294 [0.59126234, 0.6146234] R²: 0.02295 [0.01792423, 0.02800557] 0 beta = log(or)/sd_pgs
PPM020056 PGS004021
(lassosum.CV.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.61006 [1.57707721, 1.6437293]
β: 0.47627 [0.45557327, 0.49696762]		 AUROC: 0.63039 [0.62463626, 0.63613412] R²: 0.03371 [0.03082787, 0.03667513] 0 beta = log(or)/sd_pgs
PPM020057 PGS004021
(lassosum.CV.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.91213 [1.49624529, 2.4436175]
β: 0.64822 [0.40295883, 0.89347952]		 AUROC: 0.69067 [0.62429924, 0.75703169] R²: 0.03819 [0.01668401, 0.0690534] 0 beta = log(or)/sd_pgs
PPM020058 PGS004021
(lassosum.CV.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.4387 [1.3566017, 1.52577159]
β: 0.36374 [0.30498282, 0.42250024]		 AUROC: 0.60312 [0.58631707, 0.61991468] R²: 0.01973 [0.01358075, 0.02702473] 0 beta = log(or)/sd_pgs
PPM020059 PGS004021
(lassosum.CV.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 2.11267 [1.86259241, 2.39632917]
β: 0.74795 [0.62196928, 0.87393805]		 AUROC: 0.71102 [0.67560891, 0.74643625] R²: 0.09939 [0.0673612, 0.13982338] 0 beta = log(or)/sd_pgs
PPM020001 PGS004049
(ldpred2.CV.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.63972 [1.60628474, 1.67385776]
β: 0.49453 [0.47392389, 0.515131]		 AUROC: 0.6351 [0.62933904, 0.64086446] R²: 0.0367 [0.03357391, 0.04012387] 0 beta = log(or)/sd_pgs
PPM020002 PGS004049
(ldpred2.CV.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.9896 [1.59472086, 2.48224985]
β: 0.68793 [0.46669871, 0.90916534]		 AUROC: 0.70565 [0.63333493, 0.77796963] R²: 0.05367 [0.02290313, 0.09716264] 0 beta = log(or)/sd_pgs
PPM020003 PGS004049
(ldpred2.CV.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.54092 [1.45306104, 1.63408316]
β: 0.43238 [0.37367239, 0.49108189]		 AUROC: 0.61952 [0.60270134, 0.636339] R²: 0.02797 [0.0211408, 0.03646128] 0 beta = log(or)/sd_pgs
PPM020004 PGS004049
(ldpred2.CV.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 2.36914 [2.07577111, 2.70396438]
β: 0.86253 [0.73033271, 0.99471898]		 AUROC: 0.72826 [0.69173398, 0.76478209] R²: 0.122 [0.08216417, 0.16529108] 0 beta = log(or)/sd_pgs
PPM020000 PGS004049
(ldpred2.CV.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.55377 [1.4943584, 1.61555387]
β: 0.44069 [0.40169695, 0.47967785]		 AUROC: 0.62089 [0.60918562, 0.63258519] R²: 0.03138 [0.02545406, 0.03718143] 0 beta = log(or)/sd_pgs
PPM020035 PGS004064
(megaprs.auto.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.52285 [1.46263457, 1.58555171]
β: 0.42059 [0.38023931, 0.46093243]		 AUROC: 0.61325 [0.60161044, 0.62487979] R²: 0.02644 [0.02106118, 0.03159975] 0 beta = log(or)/sd_pgs
PPM020036 PGS004064
(megaprs.auto.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.6765 [1.64253856, 1.71116433]
β: 0.51671 [0.49624295, 0.53717403]		 AUROC: 0.64169 [0.63597003, 0.64740127] R²: 0.04068 [0.03737711, 0.04388012] 0 beta = log(or)/sd_pgs
PPM020037 PGS004064
(megaprs.auto.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 2.16519 [1.63058972, 2.87505923]
β: 0.77251 [0.48894174, 1.05607327]		 AUROC: 0.68659 [0.62306752, 0.75011928] R²: 0.04033 [0.01968338, 0.06955001] 0 beta = log(or)/sd_pgs
PPM020038 PGS004064
(megaprs.auto.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.52777 [1.44093306, 1.6198353]
β: 0.42381 [0.36529086, 0.48232448]		 AUROC: 0.615 [0.59804531, 0.63195557] R²: 0.02702 [0.01945086, 0.03541182] 0 beta = log(or)/sd_pgs
PPM020039 PGS004064
(megaprs.auto.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 2.12896 [1.86473669, 2.4306247]
β: 0.75563 [0.62311986, 0.8881483]		 AUROC: 0.71237 [0.67693105, 0.74780668] R²: 0.09048 [0.06089994, 0.12628899] 0 beta = log(or)/sd_pgs
PPM020030 PGS004079
(megaprs.CV.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.50199 [1.44431953, 1.56196832]
β: 0.40679 [0.36763829, 0.44594677]		 AUROC: 0.60873 [0.59700811, 0.62044991] R²: 0.02641 [0.02099026, 0.03200156] 0 beta = log(or)/sd_pgs
PPM020031 PGS004079
(megaprs.CV.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.61696 [1.5839576, 1.65065666]
β: 0.48055 [0.45992653, 0.50117319]		 AUROC: 0.63145 [0.62565031, 0.63723984] R²: 0.03458 [0.03148347, 0.03790002] 0 beta = log(or)/sd_pgs
PPM020032 PGS004079
(megaprs.CV.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 2.0218 [1.62249081, 2.51937283]
β: 0.70399 [0.48396251, 0.92400999]		 AUROC: 0.71409 [0.65011341, 0.77806995] R²: 0.05539 [0.02757678, 0.09737164] 0 beta = log(or)/sd_pgs
PPM020033 PGS004079
(megaprs.CV.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.60515 [1.51334744, 1.70252754]
β: 0.47322 [0.41432404, 0.53211394]		 AUROC: 0.63076 [0.61433544, 0.64719353] R²: 0.03332 [0.02538049, 0.04297958] 0 beta = log(or)/sd_pgs
PPM020034 PGS004079
(megaprs.CV.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 2.22137 [1.95736288, 2.5209968]
β: 0.79813 [0.6715981, 0.92465438]		 AUROC: 0.71931 [0.68214811, 0.75647815] R²: 0.11294 [0.0751487, 0.15730633] 0 beta = log(or)/sd_pgs
PPM020045 PGS004094
(prscs.auto.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.43309 [1.37789918, 1.49048299]
β: 0.35983 [0.32056001, 0.39910022]		 AUROC: 0.60175 [0.58999494, 0.61350437] R²: 0.01993 [0.01570594, 0.02462764] 0 beta = log(or)/sd_pgs
PPM020046 PGS004094
(prscs.auto.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.64768 [1.61352054, 1.68256451]
β: 0.49937 [0.47841846, 0.52031912]		 AUROC: 0.63372 [0.62788781, 0.63955506] R²: 0.03632 [0.03309896, 0.03953108] 0 beta = log(or)/sd_pgs
PPM020047 PGS004094
(prscs.auto.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.45841 [1.19873228, 1.77432944]
β: 0.37734 [0.18126456, 0.57342257]		 AUROC: 0.60742 [0.53398957, 0.68084175] R²: 0.01948 [0.00432876, 0.05204534] 0 beta = log(or)/sd_pgs
PPM020048 PGS004094
(prscs.auto.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.30074 [1.2314019, 1.37398385]
β: 0.26293 [0.20815328, 0.31771444]		 AUROC: 0.58564 [0.56934416, 0.60192786] R²: 0.01181 [0.00719488, 0.01742899] 0 beta = log(or)/sd_pgs
PPM020049 PGS004094
(prscs.auto.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.88898 [1.67167849, 2.13453009]
β: 0.63604 [0.5138282, 0.75824653]		 AUROC: 0.69466 [0.65809177, 0.73122596] R²: 0.07313 [0.04487877, 0.10829372] 0 beta = log(or)/sd_pgs
PPM020040 PGS004103
(prscs.CV.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.39977 [1.34410643, 1.45773885]
β: 0.33631 [0.29572943, 0.3768865]		 AUROC: 0.5924 [0.58070208, 0.60409508] R²: 0.01668 [0.01284464, 0.02085219] 0 beta = log(or)/sd_pgs
PPM020041 PGS004103
(prscs.CV.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.43354 [1.40427497, 1.46341096]
β: 0.36015 [0.33952114, 0.38076998]		 AUROC: 0.60119 [0.59539073, 0.60698337] R²: 0.01933 [0.01709073, 0.021498] 0 beta = log(or)/sd_pgs
PPM020042 PGS004103
(prscs.CV.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.62378 [1.29975822, 2.02858217]
β: 0.48476 [0.26217827, 0.70733711]		 AUROC: 0.64719 [0.57521551, 0.71916706] R²: 0.0251 [0.00821845, 0.05577828] 0 beta = log(or)/sd_pgs
PPM020043 PGS004103
(prscs.CV.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.24983 [1.17898128, 1.32493323]
β: 0.22301 [0.16465075, 0.28136206]		 AUROC: 0.56468 [0.54783481, 0.58151937] R²: 0.0075 [0.00402557, 0.01180133] 0 beta = log(or)/sd_pgs
PPM020044 PGS004103
(prscs.CV.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.9189 [1.67929657, 2.19269289]
β: 0.65175 [0.51837499, 0.78513042]		 AUROC: 0.67899 [0.6419829, 0.71598959] R²: 0.06493 [0.04215202, 0.09455987] 0 beta = log(or)/sd_pgs
PPM020005 PGS004118
(pt_clump.auto.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.33056 [1.27927587, 1.3839026]
β: 0.2856 [0.24629419, 0.32490748]		 AUROC: 0.57951 [0.56779004, 0.5912348] R²: 0.01289 [0.00942678, 0.01683411] 0 beta = log(or)/sd_pgs
PPM020006 PGS004118
(pt_clump.auto.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.40296 [1.37512281, 1.43135987]
β: 0.33858 [0.31854304, 0.35862495]		 AUROC: 0.59425 [0.58836034, 0.60013257] R²: 0.01808 [0.01603989, 0.02043251] 0 beta = log(or)/sd_pgs
PPM020007 PGS004118
(pt_clump.auto.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.70576 [1.31671088, 2.20977427]
β: 0.53401 [0.27513687, 0.79289037]		 AUROC: 0.65379 [0.59209129, 0.71549218] R²: 0.02382 [0.00843075, 0.05003813] 0 beta = log(or)/sd_pgs
PPM020008 PGS004118
(pt_clump.auto.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.30274 [1.23029942, 1.37944872]
β: 0.26447 [0.20725757, 0.32168394]		 AUROC: 0.57047 [0.55330355, 0.58764034] R²: 0.01098 [0.00635806, 0.01667243] 0 beta = log(or)/sd_pgs
PPM020009 PGS004118
(pt_clump.auto.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.56663 [1.37347647, 1.78694216]
β: 0.44893 [0.31734509, 0.58050587]		 AUROC: 0.62337 [0.58200096, 0.66473232] R²: 0.03261 [0.0140955, 0.05548662] 0 beta = log(or)/sd_pgs
PPM020010 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.34749 [1.29508225, 1.40201468]
β: 0.29824 [0.25857421, 0.33791026]		 AUROC: 0.58105 [0.56930556, 0.59279972] R²: 0.0138 [0.01033525, 0.01782333] 0 beta = log(or)/sd_pgs
PPM020011 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.43562 [1.40681814, 1.46501743]
β: 0.3616 [0.34133052, 0.38186714]		 AUROC: 0.59988 [0.59403334, 0.60572738] R²: 0.02017 [0.01796729, 0.0226397] 0 beta = log(or)/sd_pgs
PPM020012 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.54617 [1.19528898, 2.00006106]
β: 0.43578 [0.17838798, 0.69317771]		 AUROC: 0.6263 [0.55995128, 0.69265647] R²: 0.01611 [0.00346998, 0.03792919] 0 beta = log(or)/sd_pgs
PPM020013 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.33067 [1.25591817, 1.40986302]
β: 0.28568 [0.22786692, 0.34349255]		 AUROC: 0.57616 [0.55915512, 0.59316854] R²: 0.01255 [0.00747678, 0.01866845] 0 beta = log(or)/sd_pgs
PPM020014 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.49068 [1.30391606, 1.70419754]
β: 0.39923 [0.26537209, 0.53309435]		 AUROC: 0.60812 [0.56762836, 0.64860873] R²: 0.02494 [0.01039785, 0.04545545] 0 beta = log(or)/sd_pgs
PPM020020 PGS004148
(sbayesr.auto.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.39911 [1.3453147, 1.45504863]
β: 0.33583 [0.29662796, 0.37503932]		 AUROC: 0.5916 [0.57985369, 0.6033368] R²: 0.01793 [0.01361181, 0.02247244] 0 beta = log(or)/sd_pgs
PPM020021 PGS004148
(sbayesr.auto.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.62873 [1.5962079, 1.66190947]
β: 0.4878 [0.46763075, 0.50796722]		 AUROC: 0.63399 [0.62818932, 0.6397817] R²: 0.03731 [0.0341354, 0.04065053] 0 beta = log(or)/sd_pgs
PPM020022 PGS004148
(sbayesr.auto.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.86907 [1.45549233, 2.40017231]
β: 0.62544 [0.37534421, 0.87554053]		 AUROC: 0.67317 [0.61055743, 0.73578134] R²: 0.03526 [0.01406596, 0.06823395] 0 beta = log(or)/sd_pgs
PPM020023 PGS004148
(sbayesr.auto.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.46527 [1.38341272, 1.55196664]
β: 0.38204 [0.32455343, 0.43952293]		 AUROC: 0.60487 [0.58809209, 0.62164016] R²: 0.02273 [0.01613462, 0.03055882] 0 beta = log(or)/sd_pgs
PPM020024 PGS004148
(sbayesr.auto.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.74045 [1.52359433, 1.98817059]
β: 0.55414 [0.42107223, 0.68721491]		 AUROC: 0.66211 [0.62585476, 0.69836134] R²: 0.04857 [0.02861608, 0.07522105] 0 beta = log(or)/sd_pgs
PPM020025 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
 PSS011222|
European Ancestry|
199,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.64114 [1.57821035, 1.70658848]
β: 0.49539 [0.45629151, 0.53449634]		 AUROC: 0.63353 [0.62188573, 0.645168] R²: 0.03944 [0.03314538, 0.04625298] 0 beta = log(or)/sd_pgs
PPM020026 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
 PSS011233|
European Ancestry|
388,890 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.75402 [1.71840512, 1.79036854]
β: 0.56191 [0.5413966, 0.58242149]		 AUROC: 0.65279 [0.64709296, 0.6584935] R²: 0.04802 [0.0444714, 0.05161881] 0 beta = log(or)/sd_pgs
PPM020027 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
 PSS011246|
South Asian Ancestry|
44,057 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 2.39078 [1.89563819, 3.0152594]
β: 0.87162 [0.63955556, 1.10368586]		 AUROC: 0.74329 [0.67891271, 0.80767425] R²: 0.07939 [0.04017912, 0.13128156] 0 beta = log(or)/sd_pgs
PPM020028 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
 PSS011262|
European Ancestry|
66,865 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 1.6676 [1.57316173, 1.76770414]
β: 0.51138 [0.45308744, 0.56968161]		 AUROC: 0.64052 [0.62389168, 0.65713902] R²: 0.03977 [0.03083288, 0.04944259] 0 beta = log(or)/sd_pgs
PPM020029 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
 PSS011275|
European Ancestry|
90,274 individuals
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Reported Trait: Seropositive RA OR: 2.46183 [2.16199209, 2.8032592]
β: 0.90091 [0.77103006, 1.03078274]		 AUROC: 0.74695 [0.71319269, 0.78070209] R²: 0.13759 [0.09865689, 0.18374268] 0 beta = log(or)/sd_pgs
PPM020323 PGS004255
(GenoBoost_rheumatoid_arthritis_0)
 PSS011342|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.66209 Covariate-adjusted pseudo-R2: 0.01285
AUPRC: 0.04621		 age, sex, PC1-10 —
PPM020324 PGS004256
(GenoBoost_rheumatoid_arthritis_1)
 PSS011342|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.66212 Covariate-adjusted pseudo-R2: 0.01305
AUPRC: 0.04649		 age, sex, PC1-10 —
PPM020325 PGS004257
(GenoBoost_rheumatoid_arthritis_2)
 PSS011342|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.66087 AUPRC: 0.04561
Covariate-adjusted pseudo-R2: 0.01191		 age, sex, PC1-10 —
PPM020326 PGS004258
(GenoBoost_rheumatoid_arthritis_3)
 PSS011342|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.6639 Covariate-adjusted pseudo-R2: 0.01382
AUPRC: 0.04737		 age, sex, PC1-10 —
PPM020327 PGS004259
(GenoBoost_rheumatoid_arthritis_4)
 PSS011342|
European Ancestry|
67,428 individuals
 PGP000546 |
Ohta R et al. Nat Commun (2024)
 Reported Trait: Rheumatoid arthritis — AUROC: 0.66128 Covariate-adjusted pseudo-R2: 0.01258
AUPRC: 0.04632		 age, sex, PC1-10 —
PPM020440 PGS004326
(PRS154_RA)
 PSS011363|
European Ancestry|
342,973 individuals
 PGP000560 |
Zhang J et al. Environ Health Perspect (2023)
 Reported Trait: Incident rheumatoid arthritis HR: 1.22 [1.17, 1.27] — — age, sex, UK Biobank assessment center, household income, education level, smoking status, body mass index, alcohol consumption, sedentary time, physical activity duration, healthy diet score, first 10 genetic principal components, and genotyping batch. —
PPM020441 PGS004326
(PRS154_RA)
 PSS011363|
European Ancestry|
342,973 individuals
 PGP000560 |
Zhang J et al. Environ Health Perspect (2023)
 Reported Trait: Incident rheumatoid arthritis with air pollution — — Hazard ratio (HR, high air pollution and PRS in top tertile vs low air pollution and PRS in bottom tertile): 1.73 [1.39, 2.17] age, sex, UK Biobank assessment center, household income, education level, smoking status, body mass index, alcohol consumption, sedentary time, physical activity duration, healthy diet score, first 10 genetic principal components, and genotyping batch. —
PPM020592 PGS004477
(disease.M13.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M13 (Other arthritis) OR: 1.1956 — — — —
PPM020593 PGS004478
(disease.M16.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M16 (Coxarthrosis [arthrosis of hip]) OR: 1.29595 — — — —
PPM020594 PGS004479
(disease.M17.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M17 (Gonarthrosis [arthrosis of knee]) OR: 1.32326 — — — —
PPM020595 PGS004480
(disease.M19.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M19 (Other arthrosis) OR: 1.21103 — — — —
PPM020598 PGS004483
(disease.M25.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M25 (Other joint disorders, not elsewhere classified) OR: 1.07361 — — — —
PPM020601 PGS004486
(disease.M51.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M51 (Other intervertebral disk disorders) OR: 1.18281 — — — —
PPM020662 PGS004547
(meta.M13.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M13 (Other arthritis) OR: 1.2622 — — — —
PPM020663 PGS004548
(meta.M16.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M16 (Coxarthrosis [arthrosis of hip]) OR: 1.21626 — — — —
PPM020664 PGS004549
(meta.M17.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M17 (Gonarthrosis [arthrosis of knee]) OR: 1.36669 — — — —
PPM020665 PGS004550
(meta.M19.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M19 (Other arthrosis) OR: 1.24824 — — — —
PPM020668 PGS004553
(meta.M25.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M25 (Other joint disorders, not elsewhere classified) OR: 1.11501 — — — —
PPM020671 PGS004556
(meta.M51.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: M51 (Other intervertebral disk disorders) OR: 1.1419 — — — —
PPM021042 PGS004817
(RA_PRSmix_eur)
 PSS011465|
European Ancestry|
9,462 individuals
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Reported Trait: Rheumatoid Arthritis — — Incremental R2 (Full model versus model with only covariates): 0.008 [0.004, 0.012] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021043 PGS004818
(RA_PRSmix_sas)
 PSS011474|
South Asian Ancestry|
8,837 individuals
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Reported Trait: Rheumatoid Arthritis — — Incremental R2 (Full model versus model with only covariates): 0.008 [0.005, 0.012] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021044 PGS004819
(RA_PRSmixPlus_eur)
 PSS011465|
European Ancestry|
9,462 individuals
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Reported Trait: Rheumatoid Arthritis — — Incremental R2 (Full model versus model with only covariates): 0.011 [0.007, 0.015] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021045 PGS004820
(RA_PRSmixPlus_sas)
 PSS011474|
South Asian Ancestry|
8,837 individuals
 PGP000604 |
Truong B et al. Cell Genom (2024)
 Reported Trait: Rheumatoid Arthritis — — Incremental R2 (Full model versus model with only covariates): 0.009 [0.005, 0.013] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021165 PGS004873
(INTERVENE_MegaPRS_RA)
 PSS011635|
European Ancestry|
447,332 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident RA HR: 1.87 [1.76, 1.99] — — PCs 1-10 —
PPM021166 PGS004873
(INTERVENE_MegaPRS_RA)
 PSS011634|
European Ancestry|
37,986 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident RA HR: 2.16 [1.96, 2.37] C-index: 0.71 [0.68, 0.74] — PCs 1-10 —
PPM021167 PGS004873
(INTERVENE_MegaPRS_RA)
 PSS011633|
European Ancestry|
69,715 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident RA HR: 1.59 [1.49, 1.68] C-index: 0.64 [0.62, 0.66] — PCs 1-10 —
PPM021168 PGS004873
(INTERVENE_MegaPRS_RA)
 PSS011632|
European Ancestry|
29,427 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident RA HR: 2.27 [1.81, 2.84] C-index: 0.73 [0.66, 0.8] — PCs 1-10 —
PPM021169 PGS004873
(INTERVENE_MegaPRS_RA)
 PSS011630|
European Ancestry|
44,188 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident RA HR: 2.13 [1.65, 2.75] — — PCs 1-10 —
PPM021170 PGS004873
(INTERVENE_MegaPRS_RA)
 PSS011631|
European Ancestry|
7,018 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident RA HR: 1.83 [1.14, 2.93] C-index: 0.85 [0.77, 0.92] — PCs 1-10 —
PPM021171 PGS004873
(INTERVENE_MegaPRS_RA)
 PSS011629|
European Ancestry|
412,090 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident RA HR: 1.65 [1.62, 1.69] C-index: 0.65 [0.65, 0.66] — PCs 1-10 —
PPM021172 PGS004873
(INTERVENE_MegaPRS_RA)
 PSS011628|
European Ancestry|
199,868 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident RA HR: 1.43 [1.38, 1.49] C-index: 0.61 [0.6, 0.62] — PCs 1-10 —
PPM021231 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PSS011593|
European Ancestry|
37,024 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident hip osteoarthritis HR: 1.16 [1.13, 1.2] C-index: 0.55 [0.54, 0.56] — PCs 1-10 —
PPM021232 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PSS011592|
European Ancestry|
69,715 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident hip osteoarthritis HR: 1.33 [1.29, 1.37] C-index: 0.58 [0.57, 0.59] — PCs 1-10 —
PPM021233 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PSS011591|
European Ancestry|
29,427 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident hip osteoarthritis HR: 1.46 [1.36, 1.56] C-index: 0.6 [0.58, 0.63] — PCs 1-10 —
PPM021234 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PSS011589|
European Ancestry|
44,188 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident hip osteoarthritis HR: 1.07 [0.88, 1.31] — — PCs 1-10 —
PPM021235 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PSS011590|
European Ancestry|
7,018 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident hip osteoarthritis HR: 1.35 [1.24, 1.48] C-index: 0.6 [0.57, 0.63] — PCs 1-10 —
PPM021236 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PSS011588|
European Ancestry|
412,090 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident hip osteoarthritis HR: 1.4 [1.38, 1.42] C-index: 0.6 [0.6, 0.6] — PCs 1-10 —
PPM021237 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PSS011587|
European Ancestry|
199,868 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident hip osteoarthritis HR: 1.15 [1.13, 1.16] C-index: 0.57 [0.56, 0.57] — PCs 1-10 —
PPM021238 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PSS011600|
European Ancestry|
37,245 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident knee osteoarthritis HR: 1.19 [1.17, 1.22] C-index: 0.56 [0.55, 0.57] — PCs 1-10 —
PPM021239 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PSS011599|
European Ancestry|
69,715 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident knee osteoarthritis HR: 1.32 [1.28, 1.35] C-index: 0.58 [0.57, 0.59] — PCs 1-10 —
PPM021240 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PSS011598|
European Ancestry|
29,427 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident knee osteoarthritis HR: 1.37 [1.3, 1.44] C-index: 0.6 [0.58, 0.61] — PCs 1-10 —
PPM021241 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PSS011596|
European Ancestry|
44,188 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident knee osteoarthritis HR: 1.17 [1.1, 1.24] — — PCs 1-10 —
PPM021242 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PSS011597|
European Ancestry|
7,018 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident knee osteoarthritis HR: 1.28 [1.17, 1.39] C-index: 0.6 [0.57, 0.62] — PCs 1-10 —
PPM021243 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PSS011595|
European Ancestry|
412,090 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident knee osteoarthritis HR: 1.32 [1.31, 1.34] C-index: 0.59 [0.58, 0.59] — PCs 1-10 —
PPM021244 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PSS011594|
European Ancestry|
199,868 individuals
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Reported Trait: Incident knee osteoarthritis HR: 1.17 [1.16, 1.18] C-index: 0.56 [0.56, 0.56] — PCs 1-10 —
PPM036596 PGS018416
(PRS_knee)
 PSS012319|
European Ancestry|
163,987 individuals
 PGP000833 |
Wei Y et al. Clin Nutr (2024)
 Reported Trait: Knee osteoarthritis — — Hazard ratio (HR, high vs low tertile): 1.43 [1.34, 1.53] age, sex, BMI, education levels, Townsend deprivation index, physical activity, ethnic background, smoking status, drinking status, family history of diseases (hypertension, cardiovascular disease, and diabetes), depression, chondroitin product intake, 10 genetic principal components, genotype measurement batch, healthy dietary score and total energy intake —
PPM036598 PGS018416
(PRS_knee)
 PSS012319|
European Ancestry|
163,987 individuals
 PGP000833 |
Wei Y et al. Clin Nutr (2024)
 Reported Trait: Knee osteoarthritis x ultra-processed food (UPF) consumption interaction — — Hazard ratio (HR, high UPF consumption and high PRS vs. low UPF consumption and low PRS): 1.56 [1.37, 1.79] age, sex, BMI, education levels, Townsend deprivation index, physical activity, ethnic background, smoking status, drinking status, family history of diseases (hypertension, cardiovascular disease, and diabetes), depression, chondroitin product intake, 10 genetic principal components, genotype measurement batch, healthy dietary score and total energy intake —
PPM036595 PGS018417
(PRS_hip)
 PSS012319|
European Ancestry|
163,987 individuals
 PGP000833 |
Wei Y et al. Clin Nutr (2024)
 Reported Trait: Hip osteoarthritis — — Hazard ratio (HR, high vs low tertile): 1.76 [1.62, 1.9] age, sex, BMI, education levels, Townsend deprivation index, physical activity, ethnic background, smoking status, drinking status, family history of diseases (hypertension, cardiovascular disease, and diabetes), depression, chondroitin product intake, 10 genetic principal components, genotype measurement batch, healthy dietary score and total energy intake —
PPM036597 PGS018417
(PRS_hip)
 PSS012319|
European Ancestry|
163,987 individuals
 PGP000833 |
Wei Y et al. Clin Nutr (2024)
 Reported Trait: Hip osteoarthritis x ultra-processed food (UPF) consumption interaction — — Hazard ratio (HR, high UPF consumption and high PRS vs. low UPF consumption and low PRS): 1.82 [1.54, 2.15] age, sex, BMI, education levels, Townsend deprivation index, physical activity, ethnic background, smoking status, drinking status, family history of diseases (hypertension, cardiovascular disease, and diabetes), depression, chondroitin product intake, 10 genetic principal components, genotype measurement batch, healthy dietary score and total energy intake —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS004183 — —
[
  • 3 cases
  • , 6,494 controls
]
 — African unspecified — UKB —
PSS004185 — —
[
  • 12 cases
  • , 24,893 controls
]
 — European non-white British ancestry UKB —
PSS004186 — —
[
  • 2 cases
  • , 7,829 controls
]
 — South Asian — UKB —
PSS004187 — —
[
  • 30 cases
  • , 67,395 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004188 — —
[
  • 5 cases
  • , 6,492 controls
]
 — African unspecified — UKB —
PSS009586 Severe progressive group as patients with the top quartile of SHS (more than 35 points) and the non-severe progressive group as the remaining patients. — 740 individuals,
14.4 % Male samples
 Mean = 48.5 years
Sd = 12.4 years		 East Asian
(Japanese)		 — IORRA —
PSS004190 — —
[
  • 32 cases
  • , 24,873 controls
]
 — European non-white British ancestry UKB —
PSS004191 — —
[
  • 18 cases
  • , 7,813 controls
]
 — South Asian — UKB —
PSS004192 — —
[
  • 127 cases
  • , 67,298 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004193 — —
[
  • 122 cases
  • , 6,375 controls
]
 — African unspecified — UKB —
PSS004706 — —
[
  • 2 cases
  • , 6,495 controls
]
 — African unspecified — UKB —
PSS004707 — —
[
  • 2 cases
  • , 1,702 controls
]
 — East Asian — UKB —
PSS004708 — —
[
  • 81 cases
  • , 24,824 controls
]
 — European non-white British ancestry UKB —
PSS004709 — —
[
  • 21 cases
  • , 7,810 controls
]
 — South Asian — UKB —
PSS004710 — —
[
  • 231 cases
  • , 67,194 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004194 — —
[
  • 19 cases
  • , 1,685 controls
]
 — East Asian — UKB —
PSS004195 — —
[
  • 409 cases
  • , 24,496 controls
]
 — European non-white British ancestry UKB —
PSS008680 — — 6,241 individuals — European Italy (South Europe) UKB —
PSS004196 — —
[
  • 197 cases
  • , 7,634 controls
]
 — South Asian — UKB —
PSS004197 — —
[
  • 1,343 cases
  • , 66,082 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS008684 — — 6,366 individuals — European Italy (South Europe) UKB —
PSS008687 — — 6,660 individuals — European Italy (South Europe) UKB —
PSS004208 — —
[
  • 85 cases
  • , 6,412 controls
]
 — African unspecified — UKB —
PSS004209 — —
[
  • 16 cases
  • , 1,688 controls
]
 — East Asian — UKB —
PSS004210 — —
[
  • 779 cases
  • , 24,126 controls
]
 — European non-white British ancestry UKB —
PSS004211 — —
[
  • 74 cases
  • , 7,757 controls
]
 — South Asian — UKB —
PSS004212 — —
[
  • 2,783 cases
  • , 64,642 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004213 — —
[
  • 443 cases
  • , 6,054 controls
]
 — African unspecified — UKB —
PSS004214 — —
[
  • 56 cases
  • , 1,648 controls
]
 — East Asian — UKB —
PSS004215 — —
[
  • 1,333 cases
  • , 23,572 controls
]
 — European non-white British ancestry UKB —
PSS004216 — —
[
  • 684 cases
  • , 7,147 controls
]
 — South Asian — UKB —
PSS004217 — —
[
  • 4,861 cases
  • , 62,564 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004228 — —
[
  • 5 cases
  • , 6,492 controls
]
 — African unspecified — UKB —
PSS004229 — —
[
  • 2 cases
  • , 1,702 controls
]
 — East Asian — UKB —
PSS004230 — —
[
  • 80 cases
  • , 24,825 controls
]
 — European non-white British ancestry UKB —
PSS004231 — —
[
  • 15 cases
  • , 7,816 controls
]
 — South Asian — UKB —
PSS004232 — —
[
  • 278 cases
  • , 67,147 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS011222 — —
[
  • 2,384 cases
  • , 196,890 controls
]
 — European — EB —
PSS009889 Radiographic hip and/or knee-OA was defined in all five cohorts by a KL score ≥ 2 for one or both joints.In the CHECK cohort, clinical OA was defined as clinically relevant hip or knee osteoarthritis by a group of 36 GPs and secondary care physicians by manually evaluating the study records over the 5-10 years of follow-up — 1,002 individuals,
21.0 % Male samples
 Mean = 55.9 years
Sd = 5.2 years		 European — NR CHECK
PSS009890 Radiographic hip and/or knee-OA was defined in all five cohorts by a KL score ≥ 2 for one or both joints.Clinical OA in the PROOF cohort was defined based on the American College of Rheumatology (ACR) definition [26], which is defined based on knee pain on most days of the last month plus at least 3 of the following clinical findings: age > 50 years, stiffness < 30 minutes, crepitus, bony tenderness, bony enlargement, and no palpable warmth. Prevalent cases were defined at baseline. — 407 individuals,
0.0 % Male samples
 Mean = 55.8 years
Sd = 3.2 years		 European — NR PROOF
PSS009891 Radiographic hip and/or knee-OA was defined in all five cohorts by a KL score ≥ 2 for one or both joints.Clinical OA in Rotterdam Study was defined as reported pain in the last month and a KL score ≥ 2 in that hip or knee joint and the control group was defined as containing all participants who had not been diagnosed with radiographic OA by the end of follow-up time. — 14,926 individuals — European — RS —
PSS000429 JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children. —
[
  • 66 cases
  • , 2,954 controls
]
,
51.46 % Male samples
 — European — CHOP —
PSS000430 JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children. —
[
  • 203 cases
  • , 2,954 controls
]
,
49.19 % Male samples
 — European — CHOP —
PSS000431 JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children. —
[
  • 135 cases
  • , 2,954 controls
]
,
50.11 % Male samples
 — European — CHOP —
PSS000432 Diagnosis of JIA by a paediatric rheumatologist. —
[
  • 16 cases
  • , 578 controls
]
,
58.59 % Male samples
 — European — CLARITY Cohort description (PMID): 23153063
PSS000433 Diagnosis of JIA by a paediatric rheumatologist. —
[
  • 159 cases
  • , 578 controls
]
,
51.15 % Male samples
 — European — CLARITY Cohort description (PMID): 23153063
PSS000434 Diagnosis of JIA by a paediatric rheumatologist. —
[
  • 75 cases
  • , 578 controls
]
,
54.82 % Male samples
 — European — CLARITY Cohort description (PMID): 23153063
PSS011233 RHEUMA_SEROPOS_OTH, ICD10: M05[8-9], ICD9: 7140A —
[
  • 9,332 cases
  • , 379,558 controls
]
 — European — FinnGen —
PSS008234 — — 5,728 individuals — South Asian India (South Asia) UKB —
PSS008235 — — 5,671 individuals — South Asian India (South Asia) UKB —
PSS011246 — —
[
  • 60 cases
  • , 43,997 controls
]
 — South Asian — G&H —
PSS008238 — — 5,964 individuals — South Asian India (South Asia) UKB —
PSS008681 — — 6,216 individuals — European Italy (South Europe) UKB —
PSS008241 — — 6,331 individuals — South Asian India (South Asia) UKB —
PSS000179 JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children. —
[
  • 559 cases
  • , 2,954 controls
]
,
47.5 % Male samples
 — European — CHOP —
PSS000180 Diagnosis of JIA by a paediatric rheumatologist. —
[
  • 362 cases
  • , 578 controls
]
,
48.9 % Male samples
 — European — CLARITY Cohort description (PMID): 23153063
PSS011262 — —
[
  • 1,139 cases
  • , 65,726 controls
]
 — European — HUNT —
PSS011275 — —
[
  • 205 cases
  • , 90,069 controls
]
 — European — UKB —
PSS011465 — — 9,462 individuals — European — AllofUs —
PSS011474 — — 8,837 individuals — South Asian — G&H —
PSS009927 — —
[
  • 969 cases
  • , 6,491 controls
]
 — European, East Asian, African unspecified, South Asian, Greater Middle Eastern (Middle Eastern, North African or Persian) — BBJ Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap
PSS000312 Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 8.0 years
[
  • 30 cases
  • , 215 controls
]
,
32.0 % Male samples
 — European — PHB —
PSS000313 Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 7.0 years
[
  • 22 cases
  • , 221 controls
]
,
32.0 % Male samples
 — European — PHB —
PSS000314 Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 8.0 years
[
  • 90 cases
  • , 155 controls
]
,
32.0 % Male samples
 — European — PHB —
PSS000315 Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 7.0 years
[
  • 115 cases
  • , 128 controls
]
,
32.0 % Male samples
 — European — PHB —
PSS000316 Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 8.0 years
[
  • 31 cases
  • , 214 controls
]
,
32.0 % Male samples
 — European — PHB —
PSS000317 Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 7.0 years
[
  • 8 cases
  • , 235 controls
]
,
32.0 % Male samples
 — European — PHB —
PSS009930 — —
[
  • 894 cases
  • , 2,993 controls
]
 — European — NR Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap
PSS009929 — —
[
  • 1,378 cases
  • , 20,326 controls
]
 — East Asian — BBJ Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap
PSS009928 — —
[
  • 624 cases
  • , 680 controls
]
 — African unspecified, South Asian, Greater Middle Eastern (Middle Eastern, North African or Persian) — NR Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap
PSS000321 Setting I: Based on ICD codes and expert opinion (ACR2010 criteria), in eMERGE network EMR database from Stanaway 2018; controls = other non-matching arthritis diseases Median = 16.0 years
[
  • 52 cases
  • , 1,159 controls
]
,
43.0 % Male samples
 — European, African unspecified, Asian unspecified, NR Primarily European, African and Asian ancestry eMERGE —
PSS000322 Setting I: Based on ICD codes and expert opinion (ACR2010 criteria), in eMERGE network EMR database from Stanaway 2018; controls = other non-matching arthritis diseases Median = 16.0 years
[
  • 574 cases
  • , 637 controls
]
,
43.0 % Male samples
 — European, African unspecified, Asian unspecified, NR Primarily European, African and Asian ancestry eMERGE —
PSS000323 Setting I: Based on ICD codes and expert opinion (ACR2010 criteria), in eMERGE network EMR database from Stanaway 2018; controls = other non-matching arthritis diseases Median = 16.0 years
[
  • 65 cases
  • , 1,146 controls
]
,
43.0 % Male samples
 — European, African unspecified, Asian unspecified, NR Primarily European, African and Asian ancestry eMERGE —
PSS007799 — — 2,277 individuals — African American or Afro-Caribbean Carribean UKB —
PSS007802 — — 2,358 individuals — African American or Afro-Caribbean Carribean UKB —
PSS009935 — — 1,257 individuals — European — ASPREE —
PSS007805 — — 2,484 individuals — African American or Afro-Caribbean Carribean UKB —
PSS009936 — — 1,422 individuals — European — ASPREE —
PSS009352 — — 18,393 individuals — European UK (+ Ireland) UKB —
PSS009353 — — 18,262 individuals — European UK (+ Ireland) UKB —
PSS009356 — — 18,953 individuals — European UK (+ Ireland) UKB —
PSS009359 — — 20,000 individuals — European UK (+ Ireland) UKB —
PSS000490 Cases included physician-confirmed psoriatic arthritis (PsA). Controls inclded individuals with psoriasis with no history of joint symptoms (psoriasis only - PsO). —
[
  • 140 cases
  • , 403 controls
]
 — NR — NR —
PSS009939 — — 39,444 individuals — European
(Finnish)		 — FinnGen —
PSS008903 — — 3,634 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008906 — — 3,779 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008909 — — 3,924 individuals — African unspecified Nigeria (West Africa) UKB —
PSS010115 — —
[
  • 185 cases
  • , 1,112 controls
]
 — East Asian
(Taiwanese)		 — NR TPMI
PSS011342 — —
[
  • 1,563 cases
  • , 65,865 controls
]
,
46.0 % Male samples
 — European
(White British)		 — UKB —
PSS004461 — —
[
  • 305 cases
  • , 6,192 controls
]
 — African unspecified — UKB —
PSS004462 — —
[
  • 56 cases
  • , 1,648 controls
]
 — East Asian — UKB —
PSS004463 — —
[
  • 1,688 cases
  • , 23,217 controls
]
 — European non-white British ancestry UKB —
PSS004464 — —
[
  • 425 cases
  • , 7,406 controls
]
 — South Asian — UKB —
PSS004465 — —
[
  • 6,097 cases
  • , 61,328 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS008454 — — 1,128 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS008455 — — 1,124 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS008458 — — 1,137 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS008461 — — 1,200 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS004486 — —
[
  • 5 cases
  • , 6,492 controls
]
 — African unspecified — UKB —
PSS004487 — —
[
  • 2 cases
  • , 1,702 controls
]
 — East Asian — UKB —
PSS004488 — —
[
  • 79 cases
  • , 24,826 controls
]
 — European non-white British ancestry UKB —
PSS004489 — —
[
  • 14 cases
  • , 7,817 controls
]
 — South Asian — UKB —
PSS004490 — —
[
  • 268 cases
  • , 67,157 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS004491 — —
[
  • 118 cases
  • , 6,379 controls
]
 — African unspecified — UKB —
PSS004492 — —
[
  • 18 cases
  • , 1,686 controls
]
 — East Asian — UKB —
PSS004493 — —
[
  • 399 cases
  • , 24,506 controls
]
 — European non-white British ancestry UKB —
PSS004494 — —
[
  • 194 cases
  • , 7,637 controls
]
 — South Asian — UKB —
PSS004495 — —
[
  • 1,301 cases
  • , 66,124 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS011363 ICD10: M05, M06 Median = 8.1 years
[
  • 2,034 cases
  • , 340,939 controls
]
,
46.58 % Male samples
 Mean = 57.0 years
Sd = 7.9 years		 European — UKB —
PSS011364 — — 56,192 individuals — European — UKB —
PSS012319 — — 163,987 individuals,
45.1 % Male samples
 Mean = 55.5 years
Sd = 7.9 years		 European — UKB —
PSS011587 — —
[
  • 21,639 cases
  • , 178,229 controls
]
 — European — EB —
PSS011588 — —
[
  • 22,634 cases
  • , 389,456 controls
]
 — European — FinnGen —
PSS011589 — —
[
  • 96 cases
  • , 44,092 controls
]
 — European — G&H —
PSS011590 — —
[
  • 516 cases
  • , 6,502 controls
]
 — European — GS:SFHS —
PSS011591 — —
[
  • 839 cases
  • , 28,588 controls
]
 — European — GEL —
PSS011592 — —
[
  • 4,219 cases
  • , 65,496 controls
]
 — European — HUNT —
PSS011593 — —
[
  • 5,536 cases
  • , 31,488 controls
]
 — European — MGBB —
PSS011594 — —
[
  • 38,047 cases
  • , 161,821 controls
]
 — European — EB —
PSS011595 — —
[
  • 46,914 cases
  • , 365,176 controls
]
 — European — FinnGen —
PSS011596 — —
[
  • 1,053 cases
  • , 43,135 controls
]
 — European — G&H —
PSS011597 — —
[
  • 538 cases
  • , 6,480 controls
]
 — European — GS:SFHS —
PSS011598 — —
[
  • 1,600 cases
  • , 27,827 controls
]
 — European — GEL —
PSS011599 — —
[
  • 5,041 cases
  • , 64,674 controls
]
 — European — HUNT —
PSS011600 — —
[
  • 8,184 cases
  • , 29,061 controls
]
 — European — MGBB —
PSS008014 — — 1,754 individuals — East Asian China (East Asia) UKB —
PSS008017 — — 1,759 individuals — East Asian China (East Asia) UKB —
PSS008019 — — 1,810 individuals — East Asian China (East Asia) UKB —
PSS011629 — —
[
  • 9,610 cases
  • , 402,480 controls
]
 — European — FinnGen —
PSS011630 — —
[
  • 58 cases
  • , 44,130 controls
]
 — European — G&H —
PSS011631 — —
[
  • 18 cases
  • , 7,000 controls
]
 — European — GS:SFHS —
PSS011632 — —
[
  • 71 cases
  • , 29,356 controls
]
 — European — GEL —
PSS011633 — —
[
  • 1,072 cases
  • , 68,643 controls
]
 — European — HUNT —
PSS011634 — —
[
  • 384 cases
  • , 37,602 controls
]
 — European — MGBB —
PSS011635 — —
[
  • 994 cases
  • , 446,338 controls
]
 — European — UKB —
PSS011628 — —
[
  • 2,348 cases
  • , 197,520 controls
]
 — European — EB —
PSS004627 — —
[
  • 407 cases
  • , 6,090 controls
]
 — African unspecified — UKB —
PSS004628 — —
[
  • 36 cases
  • , 1,668 controls
]
 — East Asian — UKB —
PSS004629 — —
[
  • 1,244 cases
  • , 23,661 controls
]
 — European non-white British ancestry UKB —
PSS004630 — —
[
  • 538 cases
  • , 7,293 controls
]
 — South Asian — UKB —
PSS004631 — —
[
  • 4,088 cases
  • , 63,337 controls
]
 — European white British ancestry UKB Testing cohort (heldout set)
PSS009126 — — 3,878 individuals — European Poland (NE Europe) UKB —
PSS009127 — — 3,854 individuals — European Poland (NE Europe) UKB —
PSS009130 — — 3,909 individuals — European Poland (NE Europe) UKB —
PSS009133 — — 4,136 individuals — European Poland (NE Europe) UKB —