Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS000356
(PRSWEB_PHECODE10001_UKBB-SAIGE-HRC-X10001_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Any cancer cancer 179
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000356/ScoringFiles/PGS000356.txt.gz
PGS000773
(PRS179_BC)
 PGP000179 |
Du Z et al. J Natl Cancer Inst (2021)
 Breast cancer breast carcinoma 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000773/ScoringFiles/PGS000773.txt.gz
PGS000774
(PRS179_ERpos)
 PGP000179 |
Du Z et al. J Natl Cancer Inst (2021)
 Estrogen receptor positive breast cancer estrogen-receptor positive breast cancer 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000774/ScoringFiles/PGS000774.txt.gz
PGS000775
(PRS179_ERneg)
 PGP000179 |
Du Z et al. J Natl Cancer Inst (2021)
 Estrogen receptor negative breast cancer estrogen-receptor negative breast cancer 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000775/ScoringFiles/PGS000775.txt.gz
PGS001306
(GBE_HC201)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ulcerative colitis ulcerative colitis 179
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001306/ScoringFiles/PGS001306.txt.gz
PGS000751
(PRS_PrCa_EuropeanWeighted)
 PGP000156 |
Du Z et al. Int J Cancer (2019)
 Prostate cancer prostate carcinoma 178
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000751/ScoringFiles/PGS000751.txt.gz
PGS000443
(PRSWEB_PHECODE172.2_UKBB-SAIGE-HRC-X172.2_PT_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Other non-epithelial skin cancer skin cancer 177
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000443/ScoringFiles/PGS000443.txt.gz
PGS000899
(PRS176_CHD)
 PGP000232 |
Feitosa MF et al. Circ Genom Precis Med (2021)
 Coronary heart disease coronary artery disease 176
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000899/ScoringFiles/PGS000899.txt.gz
PGS003265
(ExPRSweb_Creatine_CKDGen-1000Genomes-DiscoveryMeta-eGFRcrea_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Creatine) glomerular filtration rate,
creatine amount		 176
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003265/ScoringFiles/PGS003265.txt.gz
PGS003266
(ExPRSweb_Creatine_CKDGen-1000Genomes-DiscoveryMeta-eGFRcrea_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Estimated glomerular filtration rate (Creatine) glomerular filtration rate,
creatine amount		 176
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003266/ScoringFiles/PGS003266.txt.gz
PGS001310
(GBE_HC430)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Rheumatoid arthritis rheumatoid arthritis 175
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001310/ScoringFiles/PGS001310.txt.gz
PGS000530
(PRSWEB_PHECODE174.1_iCOGS-ER-positive-BRCA_PT_UKB_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Breast cancer (female) breast carcinoma 174
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000530/ScoringFiles/PGS000530.txt.gz
PGS001116
(GBE_BIN_FC2006154)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Ibuprofen use NSAID use measurement 174
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001116/ScoringFiles/PGS001116.txt.gz
PGS001701
(GBE_INI25728)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA ISOVF in tract superior thalamic radiation (R) neuroimaging measurement,
brain volume		 174
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001701/ScoringFiles/PGS001701.txt.gz
PGS001713
(GBE_INI25594)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA L1 in tract uncinate fasciculus (L) neuroimaging measurement,
brain volume		 173
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001713/ScoringFiles/PGS001713.txt.gz
PGS004637
(LDL_AFR_lassosum2)
 PGP000595 |
Zhang J et al. Nat Commun (2024)
 LDL cholesterol low density lipoprotein cholesterol measurement 173
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004637/ScoringFiles/PGS004637.txt.gz
PGS001745
(GBE_INI25517)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA MD in tract anterior thalamic radiation (L) neuroimaging measurement,
brain volume		 171
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001745/ScoringFiles/PGS001745.txt.gz
PGS000928
(GBE_HC644)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Other non-toxic goitre (time-to-event) nontoxic goiter 170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000928/ScoringFiles/PGS000928.txt.gz
PGS001715
(GBE_INI25598)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 WA L2 in tract anterior thalamic radiation (L) neuroimaging measurement,
brain volume		 170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001715/ScoringFiles/PGS001715.txt.gz
PGS003459
(PRS_CO)
 PGP000451 |
Al-Janabi A et al. J Invest Dermatol (2023)
 Atopic eczema or atopic disease atopic eczema,
allergic disease		 170
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003459/ScoringFiles/PGS003459.txt.gz
PGS000950
(GBE_HC1171)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Skin changes due to chronic exposure to nonionising radiation (time-to-event) response to radiation 169
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000950/ScoringFiles/PGS000950.txt.gz
PGS003405
(165SNP_PRS)
 PGP000422 |
Vanhoye X et al. Transl Res (2022)
 LDL cholesterol low density lipoprotein cholesterol measurement 169
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003405/ScoringFiles/PGS003405.txt.gz
PGS000742
(PHS166)
 PGP000150 |
Karunamuni RA et al. Prostate Cancer Prostatic Dis (2021)
 Prostate cancer prostate carcinoma 166
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000742/ScoringFiles/PGS000742.txt.gz
PGS004920
(GRS166_AF)
 PGP000652 |
Wang N et al. Eur Heart J (2021)
 Atrial fibrillation atrial fibrillation 166
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004920/ScoringFiles/PGS004920.txt.gz
PGS003761
(PRS165_AF)
 PGP000484 |
Zhang J et al. BMC Med (2023)
 Atrial fibrillation atrial fibrillation 165
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003761/ScoringFiles/PGS003761.txt.gz
PGS003665
(L_hippocampal_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal body volume hippocampal volume 164
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003665/ScoringFiles/PGS003665.txt.gz
PGS004595
(PRS_CHD)
 PGP000575 |
Oni-Orisan A et al. Clin Pharmacol Ther (2022)
 Coronary heart disease coronary artery disease 164
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004595/ScoringFiles/PGS004595.txt.gz
PGS000783
(CC_Breast_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Breast cancer breast carcinoma 162
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000783/ScoringFiles/PGS000783.txt.gz
PGS003461
(GRS162_AF)
 PGP000454 |
Yang L et al. NPJ Digit Med (2023)
 Atrial fibrillation atrial fibrillation 162
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003461/ScoringFiles/PGS003461.txt.gz
PGS000052
(sPRS161)
 PGP000037 |
Lakeman IMM et al. J Med Genet (2019)
 Breast cancer breast carcinoma 161
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000052/ScoringFiles/PGS000052.txt.gz
PGS000084
(CC_Prostate)
 PGP000050 |
Graff RE et al. Nat Commun (2021)
 Prostate cancer prostate carcinoma 161
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000084/ScoringFiles/PGS000084.txt.gz
PGS000795
(CC_Prostate_IV)
 PGP000186 |
Kachuri L et al. Nat Commun (2020)
 Prostate cancer prostate carcinoma 161
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000795/ScoringFiles/PGS000795.txt.gz
PGS001032
(GBE_HC31)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Uterine fibroids uterine fibroid 161
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001032/ScoringFiles/PGS001032.txt.gz
PGS004110
(pt_clump.auto.GCST007140.HDL)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 HDL cholesterol high density lipoprotein cholesterol measurement 161
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004110/ScoringFiles/PGS004110.txt.gz
PGS004921
(CAD-GRS)
 PGP000654 |
Huang Y et al. Circ Genom Precis Med (2020)
 Coronary artery disease coronary artery disease 161
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004921/ScoringFiles/PGS004921.txt.gz
PGS002821
(ExPRSweb_AgeAtMenopause_ieu-a-1004_PT_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 159
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002821/ScoringFiles/PGS002821.txt.gz
PGS002822
(ExPRSweb_AgeAtMenopause_ieu-a-1004_PLINK_UKB_20211120)
 PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
 Age at menopause age at menopause 159
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002822/ScoringFiles/PGS002822.txt.gz
PGS001272
(GBE_HC1302)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Chronic renal failure (time-to-event) chronic kidney disease 158
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001272/ScoringFiles/PGS001272.txt.gz
PGS001772
(GBE_INI23005)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 ZEBRA antigen for Epstein-Barr Virus blood immunoglobulin amount 158
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001772/ScoringFiles/PGS001772.txt.gz
PGS000798
(157SNP_GRS)
 PGP000187 |
Severance LM et al. J Cardiovasc Comput Tomogr (2019)
 Coronary heart disease coronary artery disease 157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000798/ScoringFiles/PGS000798.txt.gz
PGS001497
(GBE_INI25474)
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Mean ISOVF in cingulum cingulate gyrus on FA skeleton (R) neuroimaging measurement,
brain volume		 157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001497/ScoringFiles/PGS001497.txt.gz
PGS001834
(portability-PLR_362.29)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Macular degeneration (senile) of retina NOS age-related macular degeneration 157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001834/ScoringFiles/PGS001834.txt.gz
PGS003956
(AD_Kunkle_AFR)
 PGP000503 |
Sofer T et al. Alzheimers Res Ther (2023)
 Alzheimer's disease Alzheimer disease 157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003956/ScoringFiles/PGS003956.txt.gz
PGS005167
(PRS-PC)
 PGP000711 |
Zhu M et al. PLoS Med (2025)
 Prostate cancer prostate carcinoma 157
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005167/ScoringFiles/PGS005167.txt.gz
PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
 PGP000517 |
Monti R et al. Am J Hum Genet (2024)
 Rheumatoid arthritis rheumatoid arthritis 155
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004133/ScoringFiles/PGS004133.txt.gz
PGS004905
(PRS155_AF)
 PGP000638 |
Ma Y et al. Proc Natl Acad Sci U S A (2023)
 Atrial fibrillation atrial fibrillation 155
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004905/ScoringFiles/PGS004905.txt.gz
PGS004326
(PRS154_RA)
 PGP000560 |
Zhang J et al. Environ Health Perspect (2023)
 Rheumatoid arthritis rheumatoid arthritis 154
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004326/ScoringFiles/PGS004326.txt.gz
PGS001862
(portability-PLR_575)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Other biliary tract disease biliary tract disease 151
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001862/ScoringFiles/PGS001862.txt.gz
PGS000164
(baso_p)
 PGP000078 |
Vuckovic D et al. Cell (2020)
 Basophil percentage of white cells basophil percentage of leukocytes 150
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000164/ScoringFiles/PGS000164.txt.gz
PGS000382
(PRSWEB_PHECODE153.2_UKBB-SAIGE-HRC-X153.2_LASSOSUM_MGI_20200608)
 PGP000118 |
Fritsche LG et al. Am J Hum Genet (2020)
 Colon cancer colon carcinoma 150
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000382/ScoringFiles/PGS000382.txt.gz
Showing 4151 to 4200 of 5134 rows