| Experimental Factor Ontology (EFO) Information | |
| Identifier | EFO_0005856 |
| Description | An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain. [NCIT: C2883] | Trait category |
Other disease
|
| Synonyms |
6 synonyms
|
| Mapped terms |
12 mapped terms
|
| Child trait(s) |
14 child traits
|
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants | Ancestry distribution | Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS000114 (GRS-JIA-20) |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Juvenile Idiopathic Arthritis | juvenile idiopathic arthritis | 26 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000114/ScoringFiles/PGS000114.txt.gz |
| PGS000194 (G-PROB_Rapos) |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Rheumatoid Arthritis (CCP-positive) | ACPA-positive rheumatoid arthritis | 250 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000194/ScoringFiles/PGS000194.txt.gz |
| PGS000195 (G-PROB_Raneg) |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Rheumatoid Arthritis (CCP-negative) | ACPA-negative rheumatoid arthritis | 250 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000195/ScoringFiles/PGS000195.txt.gz |
| PGS000198 (G-PROB_PsA) |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Psoriatic arthritis | psoriatic arthritis | 250 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000198/ScoringFiles/PGS000198.txt.gz |
| PGS000199 (G-PROB_Gout) |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Gout | gout | 250 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000199/ScoringFiles/PGS000199.txt.gz |
| PGS000324 (GRS-JIA-ERA-20) |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Enthesitis-related Juvenile Idiophatic Arthritis | enthesitis-related juvenile idiopathic arthritis | 138 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000324/ScoringFiles/PGS000324.txt.gz |
| PGS000325 (GRS-JIA-Oli-20) |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Oligoarthritis Juvenile Idiophatic Arthritis | oligoarticular juvenile idiopathic arthritis | 21 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000325/ScoringFiles/PGS000325.txt.gz |
| PGS000326 (GRS-JIA-RFN-20) |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Rheumatoid-factor-negative Polyarthritis (Juvenile Idiophatic Arthritis) | polyarticular juvenile idiopathic arthritis, rheumatoid factor negative | 12 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000326/ScoringFiles/PGS000326.txt.gz |
| PGS000342 (wGRS_PsA) |
PGP000111 | Smith MP et al. J Psoriasis Psoriatic Arthritis (2020) |
Psoriatic arthritis | psoriatic arthritis | 11 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000342/ScoringFiles/PGS000342.txt.gz |
| PGS000343 (wGRS_PsA_HLA) |
PGP000111 | Smith MP et al. J Psoriasis Psoriatic Arthritis (2020) |
Psoriatic arthritis | psoriatic arthritis | 5 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000343/ScoringFiles/PGS000343.txt.gz |
| PGS000711 (HC328) |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Gout | gout | 183,332 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000711/ScoringFiles/PGS000711.txt.gz |
| PGS000967 (GBE_HC1221) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Coxarthrosis [arthrosis of hip] (time-to-event) | osteoarthritis, hip | 634 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000967/ScoringFiles/PGS000967.txt.gz |
| PGS001110 (GBE_HC1209) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reactive arthropathies (time-to-event) | reactive arthritis | 6 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001110/ScoringFiles/PGS001110.txt.gz |
| PGS001135 (GBE_HC78) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Arthritis (nos) | arthritis | 1,028 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001135/ScoringFiles/PGS001135.txt.gz |
| PGS001192 (GBE_HC1222) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Gonarthrosis [arthrosis of knee] (time-to-event) | osteoarthritis, knee | 4,525 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001192/ScoringFiles/PGS001192.txt.gz |
| PGS001248 (GBE_HC328) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Gout | gout | 880 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001248/ScoringFiles/PGS001248.txt.gz |
| PGS001249 (GBE_HC1215) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Gout (time-to-event) | gout | 1,796 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001249/ScoringFiles/PGS001249.txt.gz |
| PGS001267 (GBE_HC422) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 10 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001267/ScoringFiles/PGS001267.txt.gz |
| PGS001268 (GBE_HC1242) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ankylosing spondylitis (time-to-event) | ankylosing spondylitis | 10 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001268/ScoringFiles/PGS001268.txt.gz |
| PGS001287 (GBE_HC91) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Psoriatic arthropathy | psoriatic arthritis | 36 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001287/ScoringFiles/PGS001287.txt.gz |
| PGS001290 (GBE_HC376) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Osteoarthritis | osteoarthritis | 579 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001290/ScoringFiles/PGS001290.txt.gz |
| PGS001309 (GBE_HC1212) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Other rheumatoid arthritis (time-to-event) | rheumatoid arthritis | 323 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001309/ScoringFiles/PGS001309.txt.gz |
| PGS001310 (GBE_HC430) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 175 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001310/ScoringFiles/PGS001310.txt.gz |
| PGS001311 (GBE_HC1211) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Seropositive rheumatoid arthritis (time-to-event) | rheumatoid arthritis | 3 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001311/ScoringFiles/PGS001311.txt.gz |
| PGS001789 (1kgeur_gbmi_leaveUKBBout_Gout_pst_eff_a1_b0.5_phiauto) |
PGP000262 | Wang Y et al. Cell Genom (2023) |
Gout | gout | 910,151 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001789/ScoringFiles/PGS001789.txt.gz |
| PGS001822 (portability-PLR_274.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Gout | gout | 216 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001822/ScoringFiles/PGS001822.txt.gz |
| PGS001875 (portability-PLR_714.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 256 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001875/ScoringFiles/PGS001875.txt.gz |
| PGS001876 (portability-PLR_715.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 85 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001876/ScoringFiles/PGS001876.txt.gz |
| PGS001882 (portability-PLR_740) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Osteoarthrosis | osteoarthritis | 11,451 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001882/ScoringFiles/PGS001882.txt.gz |
| PGS002030 (portability-ldpred2_274.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Gout | gout | 163,210 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002030/ScoringFiles/PGS002030.txt.gz |
| PGS002088 (portability-ldpred2_714.1) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 95,083 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002088/ScoringFiles/PGS002088.txt.gz |
| PGS002089 (portability-ldpred2_715.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 22,026 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002089/ScoringFiles/PGS002089.txt.gz |
| PGS002094 (portability-ldpred2_740) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Osteoarthrosis | osteoarthritis | 827,887 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002094/ScoringFiles/PGS002094.txt.gz |
| PGS002260 (PRS_RA) |
PGP000286 | Honda S et al. Arthritis Rheumatol (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 43,784 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002260/ScoringFiles/PGS002260.txt.gz | |
| PGS002307 (PRS33_gout) |
PGP000329 | Zhang Y et al. BMC Med (2022) |
Gout | gout | 33 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002307/ScoringFiles/PGS002307.txt.gz |
| PGS002728 (PRS_hip) |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Hip osteoarthritis | osteoarthritis, hip | 44 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002728/ScoringFiles/PGS002728.txt.gz |
| PGS002729 (PRS_knee) |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Knee osteoarthritis | osteoarthritis, knee | 24 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002729/ScoringFiles/PGS002729.txt.gz |
| PGS002745 (metaPGS_RA) |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Rheumatoid arthritis | rheumatoid arthritis | 2,575 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002745/ScoringFiles/PGS002745.txt.gz |
| PGS002749 (PRS10_TKR) |
PGP000362 | Lacaze P et al. Arthritis Rheumatol (2022) |
Total knee replacement | osteoarthritis, knee, total knee arthroplasty |
10 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002749/ScoringFiles/PGS002749.txt.gz |
| PGS002750 (PRS37_THR) |
PGP000362 | Lacaze P et al. Arthritis Rheumatol (2022) |
Total hip replacement | total hip arthroplasty, osteoarthritis, hip |
37 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002750/ScoringFiles/PGS002750.txt.gz |
| PGS002762 (Urate_prscs) |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Gout | gout | 1,092,214 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002762/ScoringFiles/PGS002762.txt.gz |
| PGS002763 (Hip_osteoarthritis_prscs) |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Hip osteoarthritis | osteoarthritis, hip | 1,052,273 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002763/ScoringFiles/PGS002763.txt.gz |
| PGS002767 (Knee_osteoarthritis_prscs) |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Knee osteoarthritis | osteoarthritis, knee | 1,052,275 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002767/ScoringFiles/PGS002767.txt.gz |
| PGS002769 (Rheumatoid_arthritis_prscs) |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Seropositive rheumatoid arthritis | rheumatoid arthritis | 1,083,565 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002769/ScoringFiles/PGS002769.txt.gz |
| PGS003329 (PRS19_gout) |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Gout | gout | 19 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003329/ScoringFiles/PGS003329.txt.gz |
| PGS003420 (PRS100_PRScs) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 100 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003420/ScoringFiles/PGS003420.txt.gz |
| PGS003421 (PRS16_C+T) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 16 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003421/ScoringFiles/PGS003421.txt.gz |
| PGS003422 (PRS16_PRSice2) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 16 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003422/ScoringFiles/PGS003422.txt.gz |
| PGS003423 (PRS100_Lassosum) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 100 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003423/ScoringFiles/PGS003423.txt.gz |
| PGS003424 (PRS100_LDpred2) |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Ankylosing spondylitis | ankylosing spondylitis | 100 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003424/ScoringFiles/PGS003424.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM000262 | PGS000114 (GRS-JIA-20) |
PSS000179| European Ancestry| 3,513 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Juvenile Idiopathic Arthritis | OR: 1.838 [1.686, 2.007] | AUROC: 0.735 [0.712, 0.758] | — | sex, genetic PCs 1-10 | — |
| PPM000263 | PGS000114 (GRS-JIA-20) |
PSS000180| European Ancestry| 940 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Juvenile Idiopathic Arthritis | OR: 2.085 [1.773, 2.471] | AUROC: 0.738 [0.705, 0.77] | — | sex, genetic PCs 1-10 | — |
| PPM000260 | PGS000114 (GRS-JIA-20) |
PSS000179| European Ancestry| 3,513 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Juvenile Idiopathic Arthritis | OR: 1.831 [1.685, 1.991] | AUROC: 0.657 [0.631, 0.683] | — | — | — |
| PPM000261 | PGS000114 (GRS-JIA-20) |
PSS000180| European Ancestry| 940 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Juvenile Idiopathic Arthritis | OR: 2.008 [1.731, 2.345] | AUROC: 0.671 [0.635, 0.706] | — | — | — |
| PPM000577 | PGS000194 (G-PROB_Rapos) |
PSS000315| European Ancestry| 243 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.69 [0.63, 0.76] | — | RAN_Gprob | (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit) |
| PPM000571 | PGS000194 (G-PROB_Rapos) |
PSS000314| European Ancestry| 245 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.75 [0.68, 0.81] | — | G-PROB_Raneg | (Setting II: Assigning patient diagnoses based on medical records) |
| PPM000565 | PGS000194 (G-PROB_Rapos) |
PSS000322| Multi-ancestry (including European)| 1,211 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.69 [0.65, 0.72] | — | G-PROB_Raneg | (Setting I: Assigning patient diagnoses based on billing codes) |
| PPM000578 | PGS000195 (G-PROB_Raneg) |
PSS000315| European Ancestry| 243 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.69 [0.63, 0.76] | — | G-PROB_Rapos | (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit) |
| PPM000572 | PGS000195 (G-PROB_Raneg) |
PSS000314| European Ancestry| 245 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.75 [0.68, 0.81] | — | G-PROB_Rapos | (Setting II: Assigning patient diagnoses based on medical records) |
| PPM000566 | PGS000195 (G-PROB_Raneg) |
PSS000322| Multi-ancestry (including European)| 1,211 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis | — | AUROC: 0.69 [0.65, 0.72] | — | G-PROB_Rapos | (Setting I: Assigning patient diagnoses based on billing codes) |
| PPM000581 | PGS000198 (G-PROB_PsA) |
PSS000313| European Ancestry| 243 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis | — | AUROC: 0.62 [0.48, 0.8] | — | — | (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit) |
| PPM000575 | PGS000198 (G-PROB_PsA) |
PSS000312| European Ancestry| 245 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis | — | AUROC: 0.71 [0.63, 0.82] | — | — | (Setting II: Assigning patient diagnoses based on medical records) |
| PPM000569 | PGS000198 (G-PROB_PsA) |
PSS000321| Multi-ancestry (including European)| 1,211 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis | — | AUROC: 0.61 [0.52, 0.69] | — | — | (Setting I: Assigning patient diagnoses based on billing codes) |
| PPM000582 | PGS000199 (G-PROB_Gout) |
PSS000311| European Ancestry| 243 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Gout diagnosis in patient with arthritis | — | AUROC: 0.85 [0.8, 0.91] | — | — | (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit) |
| PPM000576 | PGS000199 (G-PROB_Gout) |
PSS000310| European Ancestry| 245 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Gout diagnosis in patient with arthritis | — | AUROC: 0.82 [0.73, 0.94] | — | — | (Setting II: Assigning patient diagnoses based on medical records) |
| PPM000570 | PGS000199 (G-PROB_Gout) |
PSS000320| Multi-ancestry (including European)| 1,211 individuals |
PGP000081 | Knevel R et al. Sci Transl Med (2020) |
Reported Trait: Gout diagnosis in patient with arthritis | — | AUROC: 0.78 [0.75, 0.8] | — | — | (Setting I: Assigning patient diagnoses based on billing codes) |
| PPM000874 | PGS000324 (GRS-JIA-ERA-20) |
PSS000432| European Ancestry| 594 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Enthesitis-related Arthritis | OR: 3.09 [2.07, 5.04] | AUROC: 0.93 [0.86, 0.99] | — | sex, genetic PCs 1-10 | — |
| PPM000873 | PGS000324 (GRS-JIA-ERA-20) |
PSS000429| European Ancestry| 3,020 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Enthesitis-related Arthritis | OR: 1.86 [1.61, 2.14] | AUROC: 0.75 [0.68, 0.82] | — | sex, genetic PCs 1-10 | — |
| PPM000867 | PGS000324 (GRS-JIA-ERA-20) |
PSS000429| European Ancestry| 3,020 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Enthesitis-related Arthritis | OR: 1.84 [1.6, 2.17] | AUROC: 0.7 [0.63, 0.77] | — | — | — |
| PPM000868 | PGS000324 (GRS-JIA-ERA-20) |
PSS000432| European Ancestry| 594 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Enthesitis-related Arthritis | OR: 2.99 [2.11, 4.54] | AUROC: 0.84 [0.71, 0.97] | — | — | — |
| PPM000875 | PGS000325 (GRS-JIA-Oli-20) |
PSS000430| European Ancestry| 3,157 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis | OR: 1.93 [1.75, 2.13] | AUROC: 0.8 [0.77, 0.84] | — | sex, genetic PCs 1-10 | — |
| PPM000876 | PGS000325 (GRS-JIA-Oli-20) |
PSS000433| European Ancestry| 737 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis | OR: 2.19 [1.81, 2.71] | AUROC: 0.79 [0.76, 0.83] | — | sex, genetic PCs 1-10 | — |
| PPM000869 | PGS000325 (GRS-JIA-Oli-20) |
PSS000430| European Ancestry| 3,157 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis | OR: 1.93 [1.76, 2.11] | AUROC: 0.77 [0.73, 0.8] | — | — | — |
| PPM000870 | PGS000325 (GRS-JIA-Oli-20) |
PSS000433| European Ancestry| 737 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis | OR: 2.24 [1.88, 2.71] | AUROC: 0.74 [0.7, 0.79] | — | — | — |
| PPM000878 | PGS000326 (GRS-JIA-RFN-20) |
PSS000434| European Ancestry| 653 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Rheumatoid-factor-negative Polyarthritis | OR: 1.71 [1.42, 2.07] | AUROC: 0.74 [0.68, 0.8] | — | sex, genetic PCs 1-10 | — |
| PPM000872 | PGS000326 (GRS-JIA-RFN-20) |
PSS000434| European Ancestry| 653 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Rheumatoid-factor-negative Polyarthritis | OR: 1.69 [1.42, 2.02] | AUROC: 0.66 [0.59, 0.73] | — | — | — |
| PPM000877 | PGS000326 (GRS-JIA-RFN-20) |
PSS000431| European Ancestry| 3,089 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Rheumatoid-factor-negative Polyarthritis | OR: 1.51 [1.35, 1.68] | AUROC: 0.76 [0.72, 0.8] | — | sex, genetic PCs 1-10 | — |
| PPM000871 | PGS000326 (GRS-JIA-RFN-20) |
PSS000431| European Ancestry| 3,089 individuals |
PGP000052 | Cánovas R et al. Ann Rheum Dis (2020) |
Reported Trait: Rheumatoid-factor-negative Polyarthritis | OR: 1.48 [1.33, 1.64] | AUROC: 0.64 [0.59, 0.69] | — | — | — |
| PPM000971 | PGS000342 (wGRS_PsA) |
PSS000490| Ancestry Not Reported| 543 individuals |
PGP000111 | Smith MP et al. J Psoriasis Psoriatic Arthritis (2020) |
Reported Trait: Psoriatic arthritis | — | AUROC: 0.562 [0.506, 0.618] | — | — | — |
| PPM000972 | PGS000343 (wGRS_PsA_HLA) |
PSS000490| Ancestry Not Reported| 543 individuals |
PGP000111 | Smith MP et al. J Psoriasis Psoriatic Arthritis (2020) |
Reported Trait: Psoriatic arthritis | — | AUROC: 0.569 [0.513, 0.625] | — | — | — |
| PPM001603 | PGS000711 (HC328) |
PSS000815| European Ancestry| 87,413 individuals |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Reported Trait: Gout | — | AUROC: 0.7107 | — | Age, sex, PCs(1-10) | — |
| PPM001616 | PGS000711 (HC328) |
PSS000816| European Ancestry| 135,300 individuals |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Reported Trait: Gout | HR: 1.58 [1.51, 1.65] | C-index: 0.673 | — | Age as time scale, sex, batch, PCs(1-10) | — |
| PPM007658 | PGS000967 (GBE_HC1221) |
PSS004208| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE coxarthrosis [arthrosis of hip] | — | AUROC: 0.63448 [0.57611, 0.69284] | R²: 0.02258 Incremental AUROC (full-covars): 0.01789 PGS R2 (no covariates): 0.0065 PGS AUROC (no covariates): 0.57452 [0.51022, 0.63883] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007659 | PGS000967 (GBE_HC1221) |
PSS004209| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE coxarthrosis [arthrosis of hip] | — | AUROC: 0.67991 [0.52221, 0.83761] | R²: 0.03974 Incremental AUROC (full-covars): 0.00141 PGS R2 (no covariates): 0.00044 PGS AUROC (no covariates): 0.52299 [0.39821, 0.64778] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007660 | PGS000967 (GBE_HC1221) |
PSS004210| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE coxarthrosis [arthrosis of hip] | — | AUROC: 0.71352 [0.69682, 0.73022] | R²: 0.07227 Incremental AUROC (full-covars): 0.00368 PGS R2 (no covariates): 0.00258 PGS AUROC (no covariates): 0.54164 [0.52116, 0.56213] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007661 | PGS000967 (GBE_HC1221) |
PSS004211| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE coxarthrosis [arthrosis of hip] | — | AUROC: 0.72467 [0.66733, 0.78201] | R²: 0.06598 Incremental AUROC (full-covars): -0.00237 PGS R2 (no covariates): 1e-05 PGS AUROC (no covariates): 0.50363 [0.44232, 0.56493] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM007662 | PGS000967 (GBE_HC1221) |
PSS004212| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE coxarthrosis [arthrosis of hip] | — | AUROC: 0.69051 [0.68108, 0.69995] | R²: 0.06247 Incremental AUROC (full-covars): 0.00918 PGS R2 (no covariates): 0.00628 PGS AUROC (no covariates): 0.5611 [0.55051, 0.57168] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008289 | PGS001110 (GBE_HC1209) |
PSS004183| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE reactive arthropathies | — | AUROC: 0.9594 [0.92062, 0.99818] | R²: 0.17918 Incremental AUROC (full-covars): 0.00395 PGS R2 (no covariates): 0.00991 PGS AUROC (no covariates): 0.72061 [0.49213, 0.9491] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008290 | PGS001110 (GBE_HC1209) |
PSS004185| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE reactive arthropathies | — | AUROC: 0.77096 [0.63921, 0.90271] | R²: 0.09743 Incremental AUROC (full-covars): 0.03274 PGS R2 (no covariates): 0.03411 PGS AUROC (no covariates): 0.65137 [0.47674, 0.826] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008291 | PGS001110 (GBE_HC1209) |
PSS004186| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE reactive arthropathies | — | AUROC: 0.94552 [0.83969, 1.0] | R²: 0.25627 Incremental AUROC (full-covars): 0.00045 PGS R2 (no covariates): 0.00071 PGS AUROC (no covariates): 0.67786 [0.66768, 0.68805] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008292 | PGS001110 (GBE_HC1209) |
PSS004187| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE reactive arthropathies | — | AUROC: 0.6839 [0.58647, 0.78132] | R²: 0.03053 Incremental AUROC (full-covars): 0.07922 PGS R2 (no covariates): 0.02879 PGS AUROC (no covariates): 0.66167 [0.54859, 0.77475] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008403 | PGS001135 (GBE_HC78) |
PSS004627| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Arthritis (nos) | — | AUROC: 0.7166 [0.69191, 0.7413] | R²: 0.0961 Incremental AUROC (full-covars): -0.00204 PGS R2 (no covariates): 0.0 PGS AUROC (no covariates): 0.50267 [0.47421, 0.53114] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008404 | PGS001135 (GBE_HC78) |
PSS004628| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Arthritis (nos) | — | AUROC: 0.78855 [0.73521, 0.8419] | R²: 0.13042 Incremental AUROC (full-covars): -0.00593 PGS R2 (no covariates): 0.00821 PGS AUROC (no covariates): 0.42483 [0.32454, 0.52511] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008405 | PGS001135 (GBE_HC78) |
PSS004629| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Arthritis (nos) | — | AUROC: 0.67424 [0.65969, 0.68878] | R²: 0.05468 Incremental AUROC (full-covars): 0.00314 PGS R2 (no covariates): 0.00291 PGS AUROC (no covariates): 0.53928 [0.52302, 0.55554] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008406 | PGS001135 (GBE_HC78) |
PSS004630| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Arthritis (nos) | — | AUROC: 0.71014 [0.68888, 0.73139] | R²: 0.08893 Incremental AUROC (full-covars): 0.00207 PGS R2 (no covariates): 0.00153 PGS AUROC (no covariates): 0.52639 [0.5015, 0.55128] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008407 | PGS001135 (GBE_HC78) |
PSS004631| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Arthritis (nos) | — | AUROC: 0.64961 [0.64135, 0.65786] | R²: 0.04342 Incremental AUROC (full-covars): 0.00228 PGS R2 (no covariates): 0.00147 PGS AUROC (no covariates): 0.52671 [0.51771, 0.53571] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008609 | PGS001192 (GBE_HC1222) |
PSS004213| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gonarthrosis [arthrosis of knee] | — | AUROC: 0.68497 [0.65949, 0.71044] | R²: 0.07256 Incremental AUROC (full-covars): -0.01106 PGS R2 (no covariates): 0.00014 PGS AUROC (no covariates): 0.48548 [0.45782, 0.51313] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008610 | PGS001192 (GBE_HC1222) |
PSS004214| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gonarthrosis [arthrosis of knee] | — | AUROC: 0.6973 [0.62907, 0.76552] | R²: 0.05404 Incremental AUROC (full-covars): -0.01876 PGS R2 (no covariates): 0.00104 PGS AUROC (no covariates): 0.48101 [0.40847, 0.55354] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008611 | PGS001192 (GBE_HC1222) |
PSS004215| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gonarthrosis [arthrosis of knee] | — | AUROC: 0.66024 [0.6461, 0.67438] | PGS R2 (no covariates): 0.00516 R²: 0.04745 Incremental AUROC (full-covars): 0.00488 PGS AUROC (no covariates): 0.54777 [0.53172, 0.56382] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008612 | PGS001192 (GBE_HC1222) |
PSS004216| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gonarthrosis [arthrosis of knee] | — | AUROC: 0.72749 [0.70853, 0.74646] | R²: 0.11678 Incremental AUROC (full-covars): 0.00024 PGS R2 (no covariates): 0.00229 PGS AUROC (no covariates): 0.53307 [0.5103, 0.55585] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008613 | PGS001192 (GBE_HC1222) |
PSS004217| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gonarthrosis [arthrosis of knee] | — | AUROC: 0.64504 [0.63733, 0.65274] | R²: 0.04312 Incremental AUROC (full-covars): 0.0104 PGS R2 (no covariates): 0.0068 PGS AUROC (no covariates): 0.55655 [0.54824, 0.56485] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008749 | PGS001248 (GBE_HC328) |
PSS004452| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Gout | — | AUROC: 0.8285 [0.79138, 0.86562] | R²: 0.15624 Incremental AUROC (full-covars): 0.01741 PGS R2 (no covariates): 0.02051 PGS AUROC (no covariates): 0.62118 [0.56505, 0.67731] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008750 | PGS001248 (GBE_HC328) |
PSS004453| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Gout | — | AUROC: 0.84973 [0.79458, 0.90489] | R²: 0.22864 Incremental AUROC (full-covars): 0.02603 PGS R2 (no covariates): 0.04315 PGS AUROC (no covariates): 0.65938 [0.56975, 0.74901] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008751 | PGS001248 (GBE_HC328) |
PSS004454| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Gout | — | AUROC: 0.83619 [0.82126, 0.85113] | R²: 0.17414 Incremental AUROC (full-covars): 0.02904 PGS R2 (no covariates): 0.03561 PGS AUROC (no covariates): 0.66092 [0.63744, 0.6844] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008752 | PGS001248 (GBE_HC328) |
PSS004455| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Gout | — | AUROC: 0.77913 [0.74649, 0.81177] | R²: 0.11671 Incremental AUROC (full-covars): 0.03258 PGS R2 (no covariates): 0.0283 PGS AUROC (no covariates): 0.63533 [0.59256, 0.6781] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008753 | PGS001248 (GBE_HC328) |
PSS004456| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Gout | — | AUROC: 0.81572 [0.80628, 0.82516] | Incremental AUROC (full-covars): 0.04061 PGS R2 (no covariates): 0.04014 R²: 0.15436 PGS AUROC (no covariates): 0.66908 [0.65556, 0.6826] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008754 | PGS001249 (GBE_HC1215) |
PSS004203| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gout | — | AUROC: 0.77537 [0.73576, 0.81498] | R²: 0.12063 Incremental AUROC (full-covars): 0.01433 PGS R2 (no covariates): 0.01201 PGS AUROC (no covariates): 0.58952 [0.54447, 0.63458] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008755 | PGS001249 (GBE_HC1215) |
PSS004204| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gout | — | AUROC: 0.8503 [0.79897, 0.90164] | R²: 0.23863 Incremental AUROC (full-covars): 0.01971 PGS R2 (no covariates): 0.02733 PGS AUROC (no covariates): 0.62617 [0.54055, 0.7118] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008756 | PGS001249 (GBE_HC1215) |
PSS004205| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gout | — | AUROC: 0.81772 [0.80388, 0.83156] | R²: 0.17135 Incremental AUROC (full-covars): 0.02929 PGS R2 (no covariates): 0.03724 PGS AUROC (no covariates): 0.65807 [0.63913, 0.67702] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008757 | PGS001249 (GBE_HC1215) |
PSS004206| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gout | — | AUROC: 0.76492 [0.73884, 0.79099] | PGS AUROC (no covariates): 0.61344 [0.57941, 0.64746] R²: 0.11928 Incremental AUROC (full-covars): 0.02377 PGS R2 (no covariates): 0.02209 |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008758 | PGS001249 (GBE_HC1215) |
PSS004207| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE gout | — | AUROC: 0.79258 [0.7842, 0.80095] | R²: 0.14867 Incremental AUROC (full-covars): 0.03784 PGS R2 (no covariates): 0.03919 PGS AUROC (no covariates): 0.65389 [0.64293, 0.66484] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008840 | PGS001267 (GBE_HC422) |
PSS004486| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.86744 [0.75569, 0.97918] | R²: 0.1463 Incremental AUROC (full-covars): -0.00062 PGS R2 (no covariates): 0.00216 PGS AUROC (no covariates): 0.4722 [0.12421, 0.82018] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008841 | PGS001267 (GBE_HC422) |
PSS004487| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.98913 [0.972, 1.0] | R²: 0.44316 Incremental AUROC (full-covars): 0.0423 PGS R2 (no covariates): 0.24382 PGS AUROC (no covariates): 0.81698 [0.46329, 1.0] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008842 | PGS001267 (GBE_HC422) |
PSS004488| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.73638 [0.67151, 0.80124] | R²: 0.10414 Incremental AUROC (full-covars): 0.06004 PGS R2 (no covariates): 0.07222 PGS AUROC (no covariates): 0.67545 [0.60736, 0.74353] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008843 | PGS001267 (GBE_HC422) |
PSS004489| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.73535 [0.61203, 0.85867] | R²: 0.03713 Incremental AUROC (full-covars): -0.01782 PGS R2 (no covariates): 0.00902 PGS AUROC (no covariates): 0.42181 [0.29024, 0.55338] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008844 | PGS001267 (GBE_HC422) |
PSS004490| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.74328 [0.70673, 0.77983] | R²: 0.10925 Incremental AUROC (full-covars): 0.12994 PGS R2 (no covariates): 0.09877 PGS AUROC (no covariates): 0.72651 [0.68965, 0.76337] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008845 | PGS001268 (GBE_HC1242) |
PSS004228| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.86811 [0.75774, 0.97849] | R²: 0.14598 Incremental AUROC (full-covars): 6e-05 PGS R2 (no covariates): 0.00104 PGS AUROC (no covariates): 0.48424 [0.12443, 0.84406] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008846 | PGS001268 (GBE_HC1242) |
PSS004229| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.99148 [0.9789, 1.0] | R²: 0.44858 Incremental AUROC (full-covars): 0.04465 PGS R2 (no covariates): 0.23755 PGS AUROC (no covariates): 0.81257 [0.45025, 1.0] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008847 | PGS001268 (GBE_HC1242) |
PSS004230| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.73336 [0.66901, 0.79772] | R²: 0.10217 Incremental AUROC (full-covars): 0.0575 PGS R2 (no covariates): 0.06991 PGS AUROC (no covariates): 0.67405 [0.607, 0.74111] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008848 | PGS001268 (GBE_HC1242) |
PSS004231| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.73282 [0.61573, 0.84991] | R²: 0.03979 Incremental AUROC (full-covars): -0.01963 PGS R2 (no covariates): 0.00774 PGS AUROC (no covariates): 0.4297 [0.29438, 0.56502] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008849 | PGS001268 (GBE_HC1242) |
PSS004232| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE ankylosing spondylitis | — | AUROC: 0.74878 [0.71314, 0.78442] | R²: 0.115 Incremental AUROC (full-covars): 0.12686 PGS R2 (no covariates): 0.10232 PGS AUROC (no covariates): 0.7346 [0.69884, 0.77037] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008933 | PGS001287 (GBE_HC91) |
PSS004706| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.98006 [0.94602, 1.0] | Incremental AUROC (full-covars): 0.00516 R²: 0.29301 PGS R2 (no covariates): 0.01017 PGS AUROC (no covariates): 0.72132 [0.63231, 0.81034] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008934 | PGS001287 (GBE_HC91) |
PSS004707| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.99354 [0.98059, 1.0] | R²: 0.5357 Incremental AUROC (full-covars): -0.00088 PGS R2 (no covariates): 0.00227 PGS AUROC (no covariates): 0.47826 [0.0, 0.96911] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008935 | PGS001287 (GBE_HC91) |
PSS004708| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.72814 [0.67154, 0.78475] | R²: 0.05154 Incremental AUROC (full-covars): 0.08346 PGS R2 (no covariates): 0.0335 PGS AUROC (no covariates): 0.67648 [0.61155, 0.7414] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008936 | PGS001287 (GBE_HC91) |
PSS004709| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.71827 [0.61363, 0.82292] | R²: 0.04395 Incremental AUROC (full-covars): 0.00838 PGS R2 (no covariates): 0.00229 PGS AUROC (no covariates): 0.56943 [0.44876, 0.69011] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008937 | PGS001287 (GBE_HC91) |
PSS004710| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Psoriatic arthropathy | — | AUROC: 0.6376 [0.60073, 0.67447] | R²: 0.02161 Incremental AUROC (full-covars): 0.0945 PGS R2 (no covariates): 0.02111 PGS AUROC (no covariates): 0.63567 [0.598, 0.67334] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008948 | PGS001290 (GBE_HC376) |
PSS004461| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Osteoarthritis | — | AUROC: 0.75416 [0.72668, 0.78163] | R²: 0.12216 Incremental AUROC (full-covars): -3e-05 PGS R2 (no covariates): 0.00052 PGS AUROC (no covariates): 0.51951 [0.48655, 0.55248] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008949 | PGS001290 (GBE_HC376) |
PSS004462| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Osteoarthritis | — | AUROC: 0.74181 [0.68024, 0.80338] | R²: 0.09715 Incremental AUROC (full-covars): -0.00139 PGS R2 (no covariates): 0.00189 PGS AUROC (no covariates): 0.54245 [0.47153, 0.61338] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008950 | PGS001290 (GBE_HC376) |
PSS004463| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Osteoarthritis | — | AUROC: 0.70244 [0.69044, 0.71444] | R²: 0.08191 Incremental AUROC (full-covars): 0.0007 PGS R2 (no covariates): 0.0006 PGS AUROC (no covariates): 0.51661 [0.5024, 0.53082] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008951 | PGS001290 (GBE_HC376) |
PSS004464| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Osteoarthritis | — | AUROC: 0.72534 [0.70181, 0.74887] | R²: 0.09768 Incremental AUROC (full-covars): -0.00173 PGS R2 (no covariates): 1e-05 PGS AUROC (no covariates): 0.49787 [0.47035, 0.52539] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM008952 | PGS001290 (GBE_HC376) |
PSS004465| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Osteoarthritis | — | AUROC: 0.67419 [0.66753, 0.68085] | R²: 0.0674 Incremental AUROC (full-covars): 0.00134 PGS R2 (no covariates): 0.00109 PGS AUROC (no covariates): 0.52166 [0.51404, 0.52927] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009039 | PGS001309 (GBE_HC1212) |
PSS004193| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.69751 [0.65515, 0.73988] | R²: 0.05129 Incremental AUROC (full-covars): -0.00017 PGS R2 (no covariates): 0.00056 PGS AUROC (no covariates): 0.52591 [0.47486, 0.57696] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009040 | PGS001309 (GBE_HC1212) |
PSS004194| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.67331 [0.56418, 0.78244] | R²: 0.07058 Incremental AUROC (full-covars): -0.02511 PGS R2 (no covariates): 0.0 PGS AUROC (no covariates): 0.50714 [0.3797, 0.63457] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009041 | PGS001309 (GBE_HC1212) |
PSS004195| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.6872 [0.66167, 0.71273] | R²: 0.04826 Incremental AUROC (full-covars): 0.02601 PGS R2 (no covariates): 0.01537 PGS AUROC (no covariates): 0.59782 [0.56885, 0.62679] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009042 | PGS001309 (GBE_HC1212) |
PSS004196| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.70239 [0.66722, 0.73755] | R²: 0.06164 Incremental AUROC (full-covars): -0.00362 PGS R2 (no covariates): 0.00158 PGS AUROC (no covariates): 0.53481 [0.4923, 0.57731] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009043 | PGS001309 (GBE_HC1212) |
PSS004197| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE other rheumatoid arthritis | — | AUROC: 0.66538 [0.65101, 0.67976] | R²: 0.03893 Incremental AUROC (full-covars): 0.03207 PGS R2 (no covariates): 0.01495 PGS AUROC (no covariates): 0.59784 [0.582, 0.61368] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009044 | PGS001310 (GBE_HC430) |
PSS004491| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.70522 [0.66309, 0.74736] | R²: 0.0544 Incremental AUROC (full-covars): 0.00203 PGS R2 (no covariates): 0.00109 PGS AUROC (no covariates): 0.53147 [0.47999, 0.58294] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009045 | PGS001310 (GBE_HC430) |
PSS004492| East Asian Ancestry| 1,704 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.66116 [0.54578, 0.77655] | R²: 0.06929 Incremental AUROC (full-covars): -0.02514 PGS R2 (no covariates): 0.00033 PGS AUROC (no covariates): 0.52178 [0.38366, 0.6599] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009046 | PGS001310 (GBE_HC430) |
PSS004493| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.68857 [0.6632, 0.71393] | R²: 0.04919 Incremental AUROC (full-covars): 0.02092 PGS R2 (no covariates): 0.01316 PGS AUROC (no covariates): 0.58714 [0.55751, 0.61676] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009047 | PGS001310 (GBE_HC430) |
PSS004494| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.70402 [0.66905, 0.73899] | R²: 0.06207 Incremental AUROC (full-covars): -0.0019 PGS R2 (no covariates): 0.00142 PGS AUROC (no covariates): 0.53137 [0.48984, 0.57291] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009048 | PGS001310 (GBE_HC430) |
PSS004495| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.66508 [0.65049, 0.67967] | R²: 0.03894 Incremental AUROC (full-covars): 0.03077 PGS R2 (no covariates): 0.01509 PGS AUROC (no covariates): 0.60018 [0.58428, 0.61607] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009049 | PGS001311 (GBE_HC1211) |
PSS004188| African Ancestry| 6,497 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seropositive rheumatoid arthritis | — | AUROC: 0.90345 [0.82233, 0.98457] | R²: 0.16794 Incremental AUROC (full-covars): -0.00669 PGS R2 (no covariates): 0.01613 PGS AUROC (no covariates): 0.39273 [0.11505, 0.67041] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009050 | PGS001311 (GBE_HC1211) |
PSS004190| European Ancestry| 24,905 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seropositive rheumatoid arthritis | — | AUROC: 0.76787 [0.6839, 0.85184] | R²: 0.08412 Incremental AUROC (full-covars): 0.0418 PGS R2 (no covariates): 0.05847 PGS AUROC (no covariates): 0.73164 [0.63667, 0.82662] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009051 | PGS001311 (GBE_HC1211) |
PSS004191| South Asian Ancestry| 7,831 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seropositive rheumatoid arthritis | — | AUROC: 0.76865 [0.6608, 0.87651] | R²: 0.08089 Incremental AUROC (full-covars): -0.00731 PGS R2 (no covariates): 0.00567 PGS AUROC (no covariates): 0.50626 [0.35145, 0.66107] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009052 | PGS001311 (GBE_HC1211) |
PSS004192| European Ancestry| 67,425 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: TTE seropositive rheumatoid arthritis | — | AUROC: 0.73785 [0.69634, 0.77936] | R²: 0.05309 Incremental AUROC (full-covars): 0.09202 PGS R2 (no covariates): 0.04612 PGS AUROC (no covariates): 0.7072 [0.65945, 0.75495] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
| PPM009309 | PGS001789 (1kgeur_gbmi_leaveUKBBout_Gout_pst_eff_a1_b0.5_phiauto) |
PSS007699| African Ancestry| 6,206 individuals |
PGP000262 | Wang Y et al. Cell Genom (2023) |
Reported Trait: Gout | — | AUROC: 0.805 | Nagelkerke's R2 (covariates regressed out): 0.01073 | sex,age,age2,age*sex,age^2*sex, 20PCs | — |
| PPM009293 | PGS001789 (1kgeur_gbmi_leaveUKBBout_Gout_pst_eff_a1_b0.5_phiauto) |
PSS007712| European Ancestry| 359,345 individuals |
PGP000262 | Wang Y et al. Cell Genom (2023) |
Reported Trait: Gout | — | AUROC: 0.807 | Nagelkerke's R2 (covariates regressed out): 0.03121 | sex,age,age2,age*sex,age^2*sex, 20PCs | — |
| PPM009304 | PGS001789 (1kgeur_gbmi_leaveUKBBout_Gout_pst_eff_a1_b0.5_phiauto) |
PSS007703| Additional Asian Ancestries| 8,184 individuals |
PGP000262 | Wang Y et al. Cell Genom (2023) |
Reported Trait: Gout | — | AUROC: 0.78 | Nagelkerke's R2 (covariates regressed out): 0.00748 | sex,age,age2,age*sex,age^2*sex, 20PCs | — |
| PPM009476 | PGS001822 (portability-PLR_274.1) |
PSS009292| European Ancestry| 19,983 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0364 [0.0226, 0.0503] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009477 | PGS001822 (portability-PLR_274.1) |
PSS009066| European Ancestry| 4,135 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.043 [0.0125, 0.0735] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009478 | PGS001822 (portability-PLR_274.1) |
PSS008620| European Ancestry| 6,655 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0538 [0.0297, 0.0777] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009479 | PGS001822 (portability-PLR_274.1) |
PSS008396| Greater Middle Eastern Ancestry| 1,200 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0122 [-0.0449, 0.0692] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009480 | PGS001822 (portability-PLR_274.1) |
PSS008174| South Asian Ancestry| 6,325 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0166 [-0.008, 0.0413] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009481 | PGS001822 (portability-PLR_274.1) |
PSS007961| East Asian Ancestry| 1,810 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0287 [-0.0176, 0.075] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009482 | PGS001822 (portability-PLR_274.1) |
PSS007742| African Ancestry| 2,480 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0314 [-0.0082, 0.0708] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009483 | PGS001822 (portability-PLR_274.1) |
PSS008845| African Ancestry| 3,918 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0294 [-0.002, 0.0607] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009888 | PGS001875 (portability-PLR_714.1) |
PSS009352| European Ancestry| 18,393 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0416 [0.0272, 0.056] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009889 | PGS001875 (portability-PLR_714.1) |
PSS009126| European Ancestry| 3,878 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0554 [0.0239, 0.0868] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009890 | PGS001875 (portability-PLR_714.1) |
PSS008680| European Ancestry| 6,241 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0322 [0.0073, 0.057] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009891 | PGS001875 (portability-PLR_714.1) |
PSS008454| Greater Middle Eastern Ancestry| 1,128 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0363 [-0.0226, 0.095] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009892 | PGS001875 (portability-PLR_714.1) |
PSS008234| South Asian Ancestry| 5,728 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0097 [-0.0163, 0.0356] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009893 | PGS001875 (portability-PLR_714.1) |
PSS008014| East Asian Ancestry| 1,754 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0277 [-0.0194, 0.0746] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009894 | PGS001875 (portability-PLR_714.1) |
PSS007799| African Ancestry| 2,277 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): -0.0138 [-0.055, 0.0275] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009895 | PGS001875 (portability-PLR_714.1) |
PSS008903| African Ancestry| 3,634 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): -0.0251 [-0.0577, 0.0075] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009896 | PGS001876 (portability-PLR_715.2) |
PSS009353| European Ancestry| 18,262 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0797 [0.0653, 0.0941] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009897 | PGS001876 (portability-PLR_715.2) |
PSS009127| European Ancestry| 3,854 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0453 [0.0137, 0.0769] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009898 | PGS001876 (portability-PLR_715.2) |
PSS008681| European Ancestry| 6,216 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0521 [0.0272, 0.0769] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009899 | PGS001876 (portability-PLR_715.2) |
PSS008455| Greater Middle Eastern Ancestry| 1,124 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.1472 [0.0889, 0.2044] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009900 | PGS001876 (portability-PLR_715.2) |
PSS008235| South Asian Ancestry| 5,671 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0279 [0.0019, 0.054] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009940 | PGS001882 (portability-PLR_740) |
PSS009359| European Ancestry| 20,000 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0409 [0.027, 0.0547] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009941 | PGS001882 (portability-PLR_740) |
PSS009133| European Ancestry| 4,136 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0415 [0.0109, 0.0719] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009942 | PGS001882 (portability-PLR_740) |
PSS008687| European Ancestry| 6,660 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0357 [0.0117, 0.0597] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009943 | PGS001882 (portability-PLR_740) |
PSS008461| Greater Middle Eastern Ancestry| 1,200 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0326 [-0.0246, 0.0895] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009944 | PGS001882 (portability-PLR_740) |
PSS008241| South Asian Ancestry| 6,331 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0211 [-0.0036, 0.0457] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009945 | PGS001882 (portability-PLR_740) |
PSS008019| East Asian Ancestry| 1,810 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0051 [-0.0412, 0.0514] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009946 | PGS001882 (portability-PLR_740) |
PSS007805| African Ancestry| 2,484 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0312 [-0.0083, 0.0706] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM009947 | PGS001882 (portability-PLR_740) |
PSS008909| African Ancestry| 3,924 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0103 [-0.0211, 0.0417] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011116 | PGS002030 (portability-ldpred2_274.1) |
PSS008620| European Ancestry| 6,655 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0476 [0.0236, 0.0716] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011114 | PGS002030 (portability-ldpred2_274.1) |
PSS009292| European Ancestry| 19,983 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0415 [0.0277, 0.0554] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011115 | PGS002030 (portability-ldpred2_274.1) |
PSS009066| European Ancestry| 4,135 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.047 [0.0165, 0.0775] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011117 | PGS002030 (portability-ldpred2_274.1) |
PSS008396| Greater Middle Eastern Ancestry| 1,200 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): -0.0053 [-0.0623, 0.0518] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011118 | PGS002030 (portability-ldpred2_274.1) |
PSS008174| South Asian Ancestry| 6,325 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0231 [-0.0015, 0.0478] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011119 | PGS002030 (portability-ldpred2_274.1) |
PSS007961| East Asian Ancestry| 1,810 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0262 [-0.0201, 0.0725] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011120 | PGS002030 (portability-ldpred2_274.1) |
PSS007742| African Ancestry| 2,480 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0336 [-0.006, 0.073] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011121 | PGS002030 (portability-ldpred2_274.1) |
PSS008845| African Ancestry| 3,918 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Gout | — | — | Partial Correlation (partial-r): 0.0254 [-0.006, 0.0568] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011564 | PGS002088 (portability-ldpred2_714.1) |
PSS009352| European Ancestry| 18,393 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0434 [0.029, 0.0578] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011565 | PGS002088 (portability-ldpred2_714.1) |
PSS009126| European Ancestry| 3,878 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0532 [0.0217, 0.0846] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011566 | PGS002088 (portability-ldpred2_714.1) |
PSS008680| European Ancestry| 6,241 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0284 [0.0036, 0.0532] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011568 | PGS002088 (portability-ldpred2_714.1) |
PSS008234| South Asian Ancestry| 5,728 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0135 [-0.0125, 0.0394] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011569 | PGS002088 (portability-ldpred2_714.1) |
PSS008014| East Asian Ancestry| 1,754 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0226 [-0.0245, 0.0696] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011570 | PGS002088 (portability-ldpred2_714.1) |
PSS007799| African Ancestry| 2,277 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): -0.0007 [-0.0419, 0.0406] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011571 | PGS002088 (portability-ldpred2_714.1) |
PSS008903| African Ancestry| 3,634 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): -0.0214 [-0.054, 0.0112] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011567 | PGS002088 (portability-ldpred2_714.1) |
PSS008454| Greater Middle Eastern Ancestry| 1,128 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | — | Partial Correlation (partial-r): 0.0403 [-0.0186, 0.099] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011572 | PGS002089 (portability-ldpred2_715.2) |
PSS009353| European Ancestry| 18,262 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0919 [0.0775, 0.1063] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011573 | PGS002089 (portability-ldpred2_715.2) |
PSS009127| European Ancestry| 3,854 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0476 [0.016, 0.0791] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011574 | PGS002089 (portability-ldpred2_715.2) |
PSS008681| European Ancestry| 6,216 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0596 [0.0348, 0.0844] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011576 | PGS002089 (portability-ldpred2_715.2) |
PSS008235| South Asian Ancestry| 5,671 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.0424 [0.0163, 0.0684] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011575 | PGS002089 (portability-ldpred2_715.2) |
PSS008455| Greater Middle Eastern Ancestry| 1,124 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ankylosing spondylitis | — | — | Partial Correlation (partial-r): 0.1631 [0.1051, 0.22] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011608 | PGS002094 (portability-ldpred2_740) |
PSS009359| European Ancestry| 20,000 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0535 [0.0397, 0.0673] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011609 | PGS002094 (portability-ldpred2_740) |
PSS009133| European Ancestry| 4,136 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0612 [0.0307, 0.0916] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011610 | PGS002094 (portability-ldpred2_740) |
PSS008687| European Ancestry| 6,660 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0544 [0.0304, 0.0783] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011611 | PGS002094 (portability-ldpred2_740) |
PSS008461| Greater Middle Eastern Ancestry| 1,200 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.025 [-0.0321, 0.082] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011612 | PGS002094 (portability-ldpred2_740) |
PSS008241| South Asian Ancestry| 6,331 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0394 [0.0148, 0.064] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011613 | PGS002094 (portability-ldpred2_740) |
PSS008019| East Asian Ancestry| 1,810 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): -0.0056 [-0.052, 0.0407] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011614 | PGS002094 (portability-ldpred2_740) |
PSS007805| African Ancestry| 2,484 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.0412 [0.0017, 0.0806] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM011615 | PGS002094 (portability-ldpred2_740) |
PSS008909| African Ancestry| 3,924 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Osteoarthrosis | — | — | Partial Correlation (partial-r): 0.022 [-0.0094, 0.0534] | sex, age, birth date, deprivation index, 16 PCs | — |
| PPM012870 | PGS002260 (PRS_RA) |
PSS009586| East Asian Ancestry| 740 individuals |
PGP000286 | Honda S et al. Arthritis Rheumatol (2022) |
Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis | — | — | OR (top vs 2nd quintile): 1.87 [1.11, 3.15] | — | — |
| PPM012871 | PGS002260 (PRS_RA) |
PSS009586| East Asian Ancestry| 740 individuals |
PGP000286 | Honda S et al. Arthritis Rheumatol (2022) |
Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis (age of onset <40 years) | — | — | OR (top vs 2nd quintile): 6.29 [1.85, 21.4] | — | — |
| PPM012872 | PGS002260 (PRS_RA) |
PSS009586| East Asian Ancestry| 740 individuals |
PGP000286 | Honda S et al. Arthritis Rheumatol (2022) |
Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis | OR: 1.3 [1.13, 1.5] | — | — | Age of onset, sex, ever-smoker, ACPAs positivity, rheumatoid factor positivity, BMI, periodontitis, use of methotrexate, use of bDMARD, HLA-DRB1 (Ser11) | — |
| PPM013045 | PGS002307 (PRS33_gout) |
PSS009665| European Ancestry| 416,481 individuals |
PGP000329 | Zhang Y et al. BMC Med (2022) |
Reported Trait: Incident gout | — | — | Hazard Ratio (HR, highest vs. lowest tertile): 1.77 [1.66, 1.89] | Sex, age, socioeconomic status, education level, C-reactive protein, serum creatinine, cholesterol, triglyceride, cardiovascular disease, diabetes, hypertension, genetic risk, each lifestyle factor, and body mass index (BMI) | — |
| PPM013046 | PGS002307 (PRS33_gout) |
PSS009665| European Ancestry| 416,481 individuals |
PGP000329 | Zhang Y et al. BMC Med (2022) |
Reported Trait: Incident gout without cardiometabolic diseases | — | — | Hazard Ratio (HR, highest vs. lowest tertile): 4.94 [3.91, 6.23] | Sex, age, socioeconomic status, education level, C-reactive protein, serum creatinine, cholesterol, triglyceride, cardiovascular disease, diabetes, hypertension, genetic risk, each lifestyle factor, and body mass index (BMI), Unfavorable lifestyle | — |
| PPM013047 | PGS002307 (PRS33_gout) |
PSS009665| European Ancestry| 416,481 individuals |
PGP000329 | Zhang Y et al. BMC Med (2022) |
Reported Trait: Incident gout with cardiometabolic diseases | — | — | Hazard Ratio (HR, highest vs. lowest tertile): 3.0 [2.62, 3.43] | Sex, age, socioeconomic status, education level, C-reactive protein, serum creatinine, cholesterol, triglyceride, cardiovascular disease, diabetes, hypertension, genetic risk, each lifestyle factor, and body mass index (BMI), Unfavorable lifestyle | — |
| PPM013048 | PGS002307 (PRS33_gout) |
PSS009665| European Ancestry| 416,481 individuals |
PGP000329 | Zhang Y et al. BMC Med (2022) |
Reported Trait: Incident gout | — | — | Hazard Ratio (HR, middle vs. lowest tertile): 1.53 [1.35, 1.74] | Sex, age, socioeconomic status, education level, C-reactive protein, serum creatinine, cholesterol, triglyceride, cardiovascular disease, diabetes, hypertension, genetic risk, each lifestyle factor, and body mass index (BMI), favorable lifestyle | — |
| PPM013049 | PGS002307 (PRS33_gout) |
PSS009665| European Ancestry| 416,481 individuals |
PGP000329 | Zhang Y et al. BMC Med (2022) |
Reported Trait: Incident gout | — | — | Hazard Ratio (HR, middle vs. lowest tertile): 2.39 [2.12, 2.7] | Sex, age, socioeconomic status, education level, C-reactive protein, serum creatinine, cholesterol, triglyceride, cardiovascular disease, diabetes, hypertension, genetic risk, each lifestyle factor, and body mass index (BMI), unfavorable lifestyle | — |
| PPM013050 | PGS002307 (PRS33_gout) |
PSS009665| European Ancestry| 416,481 individuals |
PGP000329 | Zhang Y et al. BMC Med (2022) |
Reported Trait: Incident gout | — | — | Hazard Ratio (HR, highest vs. lowest tertile): 1.98 [1.75, 2.24] | Sex, age, socioeconomic status, education level, C-reactive protein, serum creatinine, cholesterol, triglyceride, cardiovascular disease, diabetes, hypertension, genetic risk, each lifestyle factor, and body mass index (BMI), favorable lifestyle | — |
| PPM013044 | PGS002307 (PRS33_gout) |
PSS009665| European Ancestry| 416,481 individuals |
PGP000329 | Zhang Y et al. BMC Med (2022) |
Reported Trait: Incident gout | — | — | Hazard Ratio (HR, middle vs. lowest tertile): 1.44 [1.35, 1.54] | Sex, age, socioeconomic status, education level, C-reactive protein, serum creatinine, cholesterol, triglyceride, cardiovascular disease, diabetes, hypertension, genetic risk, each lifestyle factor, and body mass index (BMI) | — |
| PPM013051 | PGS002307 (PRS33_gout) |
PSS009665| European Ancestry| 416,481 individuals |
PGP000329 | Zhang Y et al. BMC Med (2022) |
Reported Trait: Incident gout | — | — | Hazard Ratio (HR, highest vs. lowest tertile): 3.13 [2.79, 3.52] | Sex, age, socioeconomic status, education level, C-reactive protein, serum creatinine, cholesterol, triglyceride, cardiovascular disease, diabetes, hypertension, genetic risk, each lifestyle factor, and body mass index (BMI), unfavorable lifestyle | — |
| PPM014781 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident severe radiographic osteoarthritis | OR: 1.33 [1.12, 1.59] | — | — | — | — |
| PPM014756 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Prevalent radiographic osteoarthritis | OR: 1.19 [1.1, 1.28] | — | — | — | — |
| PPM014757 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident radiographic osteoarthritis | OR: 1.15 [1.05, 1.26] | — | — | — | — |
| PPM014758 | PGS002728 (PRS_hip) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Prevalent radiographic osteoarthritis | OR: 1.28 [0.98, 1.65] | — | — | — | — |
| PPM014759 | PGS002728 (PRS_hip) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident radiographic osteoarthritis | OR: 0.95 [0.82, 1.11] | — | — | — | — |
| PPM014766 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Prevalent clinical osteoarthritis | OR: 1.3 [1.15, 1.46] | — | — | — | — |
| PPM014767 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident clinical osteoarthritis | OR: 1.22 [0.98, 1.51] | — | — | — | — |
| PPM014768 | PGS002728 (PRS_hip) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident clinical osteoarthritis | OR: 0.92 [0.74, 1.14] | — | — | — | — |
| PPM014773 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Prevalent total hip replacement | OR: 1.26 [1.12, 1.41] | — | — | — | — |
| PPM014774 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident total hip replacement | OR: 1.28 [1.11, 1.48] | — | — | — | — |
| PPM014775 | PGS002728 (PRS_hip) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident total hip replacement | OR: 1.09 [0.79, 1.47] | — | — | — | — |
| PPM014779 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Radiographic osteoarthritis progression | OR: 1.18 [1.09, 1.28] | — | — | — | — |
| PPM014783 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Radiographic osteoarthritis | — | AUROC: 0.59 [0.56, 0.61] | — | Age, sex | — |
| PPM014784 | PGS002728 (PRS_hip) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Radiographic osteoarthritis | — | AUROC: 0.62 [0.58, 0.65] | — | Age, sex | — |
| PPM014785 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Clinical osteoarthritis | — | AUROC: 0.62 [0.56, 0.68] | — | Age, sex | — |
| PPM014786 | PGS002728 (PRS_hip) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Clinical osteoarthritis | — | AUROC: 0.53 [0.47, 0.59] | — | Age, sex | — |
| PPM014787 | PGS002728 (PRS_hip) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Total hip replacement | — | AUROC: 0.66 [0.62, 0.70] | — | Age, sex | — |
| PPM014788 | PGS002728 (PRS_hip) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Total hip replacement | — | AUROC: 0.64 [0.55, 0.73] | — | Age, sex | — |
| PPM014760 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Prevalent radiographic osteoarthritis | OR: 1.17 [1.1, 1.24] | — | — | — | — |
| PPM014771 | PGS002729 (PRS_knee) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident clinical osteoarthritis | OR: 1.26 [1.05, 1.52] | — | — | — | — |
| PPM014793 | PGS002729 (PRS_knee) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Clinical osteoarthritis | — | AUROC: 0.6 [0.55, 0.65] | — | Age, sex, BMI | — |
| PPM014761 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident radiographic osteoarthritis | OR: 1.15 [1.06, 1.24] | — | — | — | — |
| PPM014762 | PGS002729 (PRS_knee) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Prevalent radiographic osteoarthritis | OR: 1.27 [0.96, 1.68] | — | — | — | — |
| PPM014763 | PGS002729 (PRS_knee) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident radiographic osteoarthritis | OR: 1.09 [0.93, 1.29] | — | — | — | — |
| PPM014764 | PGS002729 (PRS_knee) |
PSS009890| European Ancestry| 407 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Prevalent radiographic osteoarthritis | OR: 1.02 [0.69, 1.53] | — | — | — | — |
| PPM014765 | PGS002729 (PRS_knee) |
PSS009890| European Ancestry| 407 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident radiographic osteoarthritis | OR: 1.04 [0.75, 1.45] | — | — | — | — |
| PPM014769 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Prevalent clinical osteoarthritis | OR: 1.23 [1.12, 1.34] | — | — | — | — |
| PPM014770 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident clinical osteoarthritis | OR: 1.13 [0.94, 1.37] | — | — | — | — |
| PPM014772 | PGS002729 (PRS_knee) |
PSS009890| European Ancestry| 407 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident clinical osteoarthritis | OR: 1.17 [0.8, 1.73] | — | — | — | — |
| PPM014776 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Prevalent total knee replacement | OR: 1.3 [0.99, 1.71] | — | — | — | — |
| PPM014777 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident total knee replacement | OR: 1.56 [1.27, 1.91] | — | — | — | — |
| PPM014778 | PGS002729 (PRS_knee) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident total knee replacement | OR: 1.16 [0.65, 2.17] | — | — | — | — |
| PPM014780 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Radiographic osteoarthritis progression | OR: 1.18 [1.11, 1.25] | — | — | — | — |
| PPM014782 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Incident severe radiographic osteoarthritis | OR: 1.3 [1.04, 1.63] | — | — | — | — |
| PPM014789 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Radiographic osteoarthritis | — | AUROC: 0.6 [0.58, 0.63] | — | Age, sex, BMI | — |
| PPM014790 | PGS002729 (PRS_knee) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Radiographic osteoarthritis | — | AUROC: 0.57 [0.53, 0.62] | — | Age, sex, BMI | — |
| PPM014791 | PGS002729 (PRS_knee) |
PSS009890| European Ancestry| 407 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Radiographic osteoarthritis | — | AUROC: 0.53 [0.44, 0.63] | — | Age, BMI | — |
| PPM014792 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Clinical osteoarthritis | — | AUROC: 0.66 [0.61, 0.71] | — | Age, sex, BMI | — |
| PPM014794 | PGS002729 (PRS_knee) |
PSS009890| European Ancestry| 407 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Clinical osteoarthritis | — | AUROC: 0.52 [0.41, 0.63] | — | Age, BMI | — |
| PPM014795 | PGS002729 (PRS_knee) |
PSS009891| European Ancestry| 14,926 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Total hip replacement | — | AUROC: 0.66 [0.61, 0.71] | — | Age, sex, BMI | — |
| PPM014796 | PGS002729 (PRS_knee) |
PSS009889| European Ancestry| 1,002 individuals |
PGP000336 | Sedaghati-Khayat B et al. Arthritis Rheumatol (2022) |
Reported Trait: Total hip replacement | — | AUROC: 0.65 [0.49, 0.82] | — | Age, sex, BMI | — |
| PPM014915 | PGS002745 (metaPGS_RA) |
PSS009927| Multi-ancestry (including European)| 7,460 individuals |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.65 | Liability R2: 0.054 | Sex, Genotype PCs | Performance metrics are the mean values across eave-one-cohort-out cross-validation folds |
| PPM014916 | PGS002745 (metaPGS_RA) |
PSS009930| European Ancestry| 3,887 individuals |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.66 | Liability R2: 0.059 | Sex, Genotype PCs | Performance metrics are the mean values across eave-one-cohort-out cross-validation folds |
| PPM014917 | PGS002745 (metaPGS_RA) |
PSS009929| East Asian Ancestry| 21,704 individuals |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.66 | Liability R2: 0.057 | Sex, Genotype PCs | Performance metrics are the mean values across eave-one-cohort-out cross-validation folds |
| PPM014918 | PGS002745 (metaPGS_RA) |
PSS009928| Multi-ancestry (excluding European)| 1,304 individuals |
PGP000357 | Ishigaki K et al. Nat Genet (2022) |
Reported Trait: Rheumatoid arthritis | — | AUROC: 0.59 | Liability R2: 0.018 | Sex, Genotype PCs | Performance metrics are the mean values across eave-one-cohort-out cross-validation folds |
| PPM014939 | PGS002749 (PRS10_TKR) |
PSS009936| European Ancestry| 1,422 individuals |
PGP000362 | Lacaze P et al. Arthritis Rheumatol (2022) |
Reported Trait: Knee replacement | OR: 1.13 [1.07, 1.2] | — | — | Age, sex, body mass index, education, and index of relative socioeconomic advantage and disadvantage | — |
| PPM014940 | PGS002750 (PRS37_THR) |
PSS009935| European Ancestry| 1,257 individuals |
PGP000362 | Lacaze P et al. Arthritis Rheumatol (2022) |
Reported Trait: Hip replacement | OR: 1.23 [1.16, 1.3] | — | — | Age, sex, body mass index, education, and index of relative socioeconomic advantage and disadvantage | — |
| PPM014941 | PGS002750 (PRS37_THR) |
PSS009935| European Ancestry| 1,257 individuals |
PGP000362 | Lacaze P et al. Arthritis Rheumatol (2022) |
Reported Trait: Hip replacement in men | OR: 1.15 [1.06, 1.26] | — | — | Age, body mass index, education, and index of relative socioeconomic advantage and disadvantage | — |
| PPM014942 | PGS002750 (PRS37_THR) |
PSS009935| European Ancestry| 1,257 individuals |
PGP000362 | Lacaze P et al. Arthritis Rheumatol (2022) |
Reported Trait: Hip replacement in women | OR: 1.3 [1.2, 1.4] | — | — | Age, body mass index, education, and index of relative socioeconomic advantage and disadvantage | — |
| PPM014962 | PGS002762 (Urate_prscs) |
PSS009939| European Ancestry| 39,444 individuals |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Reported Trait: Gout | OR: 1.69 [1.6, 1.78] | — | — | age, sex, 10 PCs, technical covariates | — |
| PPM014963 | PGS002763 (Hip_osteoarthritis_prscs) |
PSS009939| European Ancestry| 39,444 individuals |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Reported Trait: Hip osteoarthritis | OR: 1.38 [1.31, 1.46] | — | — | age, sex, 10 PCs, technical covariates | — |
| PPM014967 | PGS002767 (Knee_osteoarthritis_prscs) |
PSS009939| European Ancestry| 39,444 individuals |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Reported Trait: Knee osteoarthritis | OR: 1.35 [1.3, 1.4] | — | — | age, sex, 10 PCs, technical covariates | — |
| PPM014969 | PGS002769 (Rheumatoid_arthritis_prscs) |
PSS009939| European Ancestry| 39,444 individuals |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Reported Trait: Seropositive rheumatoid arthritis | OR: 1.72 [1.61, 1.83] | — | — | age, sex, 10 PCs, technical covariates | — |
| PPM016117 | PGS003329 (PRS19_gout) |
PSS010039| European Ancestry| 5,522 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Age at onset of gout (in men) | β: -3.61 [-4.32, -2.9] | — | — | 10 Global PCs | — |
| PPM016120 | PGS003329 (PRS19_gout) |
PSS010039| European Ancestry| 5,522 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Tophaceous Disease (in men) | β: 1.15 [1.0, 1.31] | — | — | 10 Global PCs | — |
| PPM016123 | PGS003329 (PRS19_gout) |
PSS010039| European Ancestry| 5,522 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Age at onset of gout (in women) | β: 0.07 [-2.32, 2.45] | — | — | 10 Global PCs | — |
| PPM016126 | PGS003329 (PRS19_gout) |
PSS010039| European Ancestry| 5,522 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Tophaceous Disease (in women) | β: 0.68 [0.42, 1.1] | — | — | 10 Global PCs | — |
| PPM016119 | PGS003329 (PRS19_gout) |
PSS010040| Additional Diverse Ancestries| 869 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Age at onset of gout (in men) | β: -3.51 [-5.46, -1.57] | — | — | 10 Global PCs + 10 Oceanian PCs | — |
| PPM016121 | PGS003329 (PRS19_gout) |
PSS010038| Additional Diverse Ancestries| 1,386 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Tophaceous Disease (in men) | β: 2.6 [1.66, 4.06] | — | — | 10 Global PCs + 10 Oceanian PCs | — |
| PPM016122 | PGS003329 (PRS19_gout) |
PSS010040| Additional Diverse Ancestries| 869 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Tophaceous Disease (in men) | β: 1.53 [1.07, 2.19] | — | — | 10 Global PCs + 10 Oceanian PCs | — |
| PPM016124 | PGS003329 (PRS19_gout) |
PSS010038| Additional Diverse Ancestries| 1,386 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Age at onset of gout (in women) | β: 0.2 [-7.21, 7.62] | — | — | 10 Global PCs + 10 Oceanian PCs | — |
| PPM016125 | PGS003329 (PRS19_gout) |
PSS010040| Additional Diverse Ancestries| 869 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Age at onset of gout (in women) | β: -3.33 [-9.28, 2.62] | — | — | 10 Global PCs + 10 Oceanian PCs | — |
| PPM016127 | PGS003329 (PRS19_gout) |
PSS010038| Additional Diverse Ancestries| 1,386 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Tophaceous Disease (in women) | β: 1.45 [0.39, 5.36] | — | — | 10 Global PCs + 10 Oceanian PCs | — |
| PPM016118 | PGS003329 (PRS19_gout) |
PSS010038| Additional Diverse Ancestries| 1,386 individuals |
PGP000394 | Sumpter NA et al. Arthritis Rheumatol (2022) |
Reported Trait: Age at onset of gout (in men) | β: -6.35 [-8.91, -3.8] | — | — | 10 Global PCs + 10 Oceanian PCs | — |
| PPM017073 | PGS003420 (PRS100_PRScs) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7886 | — | — | — |
| PPM017074 | PGS003421 (PRS16_C+T) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7876 | — | — | — |
| PPM017075 | PGS003422 (PRS16_PRSice2) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7876 | — | — | — |
| PPM017076 | PGS003423 (PRS100_Lassosum) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7754 | — | — | — |
| PPM017077 | PGS003424 (PRS100_LDpred2) |
PSS010115| East Asian Ancestry| 1,298 individuals |
PGP000431 | Ko CL et al. J Transl Med (2022) |
Reported Trait: Ankylosing spondylitis | — | AUROC: 0.7605 | — | — | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS004183 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004185 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004186 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004187 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004188 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS009586 | Severe progressive group as patients with the top quartile of SHS (more than 35 points) and the non-severe progressive group as the remaining patients. | — | 740 individuals, 14.4 % Male samples |
Mean = 48.5 years Sd = 12.4 years |
East Asian (Japanese) |
— | IORRA | — |
| PSS004190 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004191 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004192 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004193 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004706 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004194 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004195 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004196 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004710 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004197 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004707 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004708 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004709 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004203 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004204 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004205 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004206 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004207 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004208 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004209 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004210 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004211 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004212 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004213 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004214 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004215 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004216 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004217 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS007699 | — | — | [
|
— | African unspecified | Africa or admixed-ancestry diaspora | UKB | — |
| PSS007703 | — | — | [
|
— | Asian unspecified | Central and South Asian | UKB | — |
| PSS004228 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004229 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004230 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004231 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004232 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS007712 | — | — | [
|
— | European | — | UKB | — |
| PSS009889 | Radiographic hip and/or knee-OA was defined in all five cohorts by a KL score ≥ 2 for one or both joints.In the CHECK cohort, clinical OA was defined as clinically relevant hip or knee osteoarthritis by a group of 36 GPs and secondary care physicians by manually evaluating the study records over the 5-10 years of follow-up | — | 1,002 individuals, 21.0 % Male samples |
Mean = 55.9 years Sd = 5.2 years |
European | — | NR | CHECK |
| PSS009890 | Radiographic hip and/or knee-OA was defined in all five cohorts by a KL score ≥ 2 for one or both joints.Clinical OA in the PROOF cohort was defined based on the American College of Rheumatology (ACR) definition [26], which is defined based on knee pain on most days of the last month plus at least 3 of the following clinical findings: age > 50 years, stiffness < 30 minutes, crepitus, bony tenderness, bony enlargement, and no palpable warmth. Prevalent cases were defined at baseline. | — | 407 individuals, 0.0 % Male samples |
Mean = 55.8 years Sd = 3.2 years |
European | — | NR | PROOF |
| PSS009891 | Radiographic hip and/or knee-OA was defined in all five cohorts by a KL score ≥ 2 for one or both joints.Clinical OA in Rotterdam Study was defined as reported pain in the last month and a KL score ≥ 2 in that hip or knee joint and the control group was defined as containing all participants who had not been diagnosed with radiographic OA by the end of follow-up time. | — | 14,926 individuals | — | European | — | RS | — |
| PSS010038 | — | — | [
|
— | Oceanian | Aotearoa NZ Maori and Cook Island Maori ancestry | NR | East Polynesian |
| PSS000429 | JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children. | — | [ ,
51.46 % Male samples |
— | European | — | CHOP | — |
| PSS000430 | JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children. | — | [ ,
49.19 % Male samples |
— | European | — | CHOP | — |
| PSS000431 | JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children. | — | [ ,
50.11 % Male samples |
— | European | — | CHOP | — |
| PSS000432 | Diagnosis of JIA by a paediatric rheumatologist. | — | [ ,
58.59 % Male samples |
— | European | — | CLARITY | Cohort description (PMID): 23153063 |
| PSS000433 | Diagnosis of JIA by a paediatric rheumatologist. | — | [ ,
51.15 % Male samples |
— | European | — | CLARITY | Cohort description (PMID): 23153063 |
| PSS000434 | Diagnosis of JIA by a paediatric rheumatologist. | — | [ ,
54.82 % Male samples |
— | European | — | CLARITY | Cohort description (PMID): 23153063 |
| PSS010039 | — | — | [
|
— | European | — | CLEAR | Australia and Aotearoa New Zealand cohort, GlobalGout, LASSO, CRYSTAL, LIGHT |
| PSS010040 | — | — | [
|
— | Oceanian | Samoan, Tongan, Niuean, Tokelauan and Pukapukan | NR | West Polynesian |
| PSS008680 | — | — | 6,241 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS008234 | — | — | 5,728 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS008235 | — | — | 5,671 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS008681 | — | — | 6,216 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS008241 | — | — | 6,331 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS000179 | JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children. | — | [ ,
47.5 % Male samples |
— | European | — | CHOP | — |
| PSS000180 | Diagnosis of JIA by a paediatric rheumatologist. | — | [ ,
48.9 % Male samples |
— | European | — | CLARITY | Cohort description (PMID): 23153063 |
| PSS008174 | — | — | 6,325 individuals | — | South Asian | India (South Asia) | UKB | — |
| PSS007742 | — | — | 2,480 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS000815 | — | — | 87,413 individuals | — | European | — | UKB | — |
| PSS000816 | ICD-10 M10 | — | [
|
— | European (Finnish) |
— | FinnGen | — |
| PSS009292 | — | — | 19,983 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS008687 | — | — | 6,660 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS000310 | Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases | Median = 8.0 years | [ ,
32.0 % Male samples |
— | European | — | PHB | — |
| PSS000311 | Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases | Median = 7.0 years | [ ,
32.0 % Male samples |
— | European | — | PHB | — |
| PSS000312 | Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases | Median = 8.0 years | [ ,
32.0 % Male samples |
— | European | — | PHB | — |
| PSS000313 | Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases | Median = 7.0 years | [ ,
32.0 % Male samples |
— | European | — | PHB | — |
| PSS000314 | Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases | Median = 8.0 years | [ ,
32.0 % Male samples |
— | European | — | PHB | — |
| PSS000315 | Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases | Median = 7.0 years | [ ,
32.0 % Male samples |
— | European | — | PHB | — |
| PSS009927 | — | — | [
|
— | European, East Asian, African unspecified, South Asian, Greater Middle Eastern (Middle Eastern, North African or Persian) | — | BBJ | Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap |
| PSS009930 | — | — | [
|
— | European | — | NR | Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap |
| PSS009929 | — | — | [
|
— | East Asian | — | BBJ | Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap |
| PSS009928 | — | — | [
|
— | African unspecified, South Asian, Greater Middle Eastern (Middle Eastern, North African or Persian) | — | NR | Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap |
| PSS000320 | Setting I: Based on ICD codes and expert opinion (ACR2010 criteria), in eMERGE network EMR database from Stanaway 2018; controls = other non-matching arthritis diseases | Median = 16.0 years | [ ,
43.0 % Male samples |
— | European, African unspecified, Asian unspecified, NR | Primarily European, African and Asian ancestry | eMERGE | — |
| PSS000321 | Setting I: Based on ICD codes and expert opinion (ACR2010 criteria), in eMERGE network EMR database from Stanaway 2018; controls = other non-matching arthritis diseases | Median = 16.0 years | [ ,
43.0 % Male samples |
— | European, African unspecified, Asian unspecified, NR | Primarily European, African and Asian ancestry | eMERGE | — |
| PSS000322 | Setting I: Based on ICD codes and expert opinion (ACR2010 criteria), in eMERGE network EMR database from Stanaway 2018; controls = other non-matching arthritis diseases | Median = 16.0 years | [ ,
43.0 % Male samples |
— | European, African unspecified, Asian unspecified, NR | Primarily European, African and Asian ancestry | eMERGE | — |
| PSS007799 | — | — | 2,277 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS009935 | — | — | 1,257 individuals | — | European | — | ASPREE | — |
| PSS007805 | — | — | 2,484 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
| PSS009936 | — | — | 1,422 individuals | — | European | — | ASPREE | — |
| PSS009352 | — | — | 18,393 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS009353 | — | — | 18,262 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS008845 | — | — | 3,918 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS009359 | — | — | 20,000 individuals | — | European | UK (+ Ireland) | UKB | — |
| PSS000490 | Cases included physician-confirmed psoriatic arthritis (PsA). Controls inclded individuals with psoriasis with no history of joint symptoms (psoriasis only - PsO). | — | [
|
— | NR | — | NR | — |
| PSS009939 | — | — | 39,444 individuals | — | European (Finnish) |
— | FinnGen | — |
| PSS009665 | Gout was ascertained based on information from self- report (Data-Field 20002, code: 1466), medical records (ICD-10 codes: M10.0, M10.2, M10.3, M10.4, M10.9), and death records (ICD-10 codes: M10.0, M10.2, M10.3, M10.4, M10.9) | Median = 12.1 years | [ ,
45.9 % Male samples |
Mean = 56.6 years Sd = 8.0 years |
European | — | UKB | — |
| PSS008903 | — | — | 3,634 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS008396 | — | — | 1,200 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS008909 | — | — | 3,924 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
| PSS010115 | — | — | [
|
— | East Asian (Taiwanese) |
— | NR | TPMI |
| PSS004452 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004453 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004454 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004455 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004456 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004461 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004462 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004463 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004464 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004465 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS008454 | — | — | 1,128 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS008455 | — | — | 1,124 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS008461 | — | — | 1,200 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
| PSS004486 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004487 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004488 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004489 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004490 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS004491 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004492 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004493 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004494 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004495 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS007961 | — | — | 1,810 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS008014 | — | — | 1,754 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS008019 | — | — | 1,810 individuals | — | East Asian | China (East Asia) | UKB | — |
| PSS009066 | — | — | 4,135 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS004627 | — | — | [
|
— | African unspecified | — | UKB | — |
| PSS004628 | — | — | [
|
— | East Asian | — | UKB | — |
| PSS004629 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
| PSS004630 | — | — | [
|
— | South Asian | — | UKB | — |
| PSS004631 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
| PSS009126 | — | — | 3,878 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS009127 | — | — | 3,854 individuals | — | European | Poland (NE Europe) | UKB | — |
| PSS008620 | — | — | 6,655 individuals | — | European | Italy (South Europe) | UKB | — |
| PSS009133 | — | — | 4,136 individuals | — | European | Poland (NE Europe) | UKB | — |