Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS018408
(MultiPRS_coronary-heart-disease)
 PGP000826 |
Ometto S et al. Nat Commun (2026)
 Coronary heart disease coronary artery disorder 1,105,536
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018408/ScoringFiles/PGS018408.txt.gz
PGS018409
(MultiPRS_heart-failure)
 PGP000826 |
Ometto S et al. Nat Commun (2026)
 Heart failure heart failure 1,105,535
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018409/ScoringFiles/PGS018409.txt.gz
PGS018410
(MultiPRS_high-cholesterol)
 PGP000826 |
Ometto S et al. Nat Commun (2026)
 Hypercholesterolaemia (high cholesterol) Hypercholesterolemia 1,105,536
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018410/ScoringFiles/PGS018410.txt.gz
PGS018411
(MultiPRS_hypertension)
 PGP000826 |
Ometto S et al. Nat Commun (2026)
 Hypertension Hypertension 1,105,536
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018411/ScoringFiles/PGS018411.txt.gz
PGS018412
(MultiPRS_myocardial-infarction)
 PGP000826 |
Ometto S et al. Nat Commun (2026)
 Myocardial infarction myocardial infarction 1,105,535
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018412/ScoringFiles/PGS018412.txt.gz
PGS018413
(MultiPRS_type-2-diabetes)
 PGP000826 |
Ometto S et al. Nat Commun (2026)
 Type 2 diabetes mellitus type 2 diabetes mellitus 1,105,536
-
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018413/ScoringFiles/PGS018413.txt.gz
PGS018414
(pgshl)
 PGP000832 |
Miao DNR et al. Hum Genomics (2024)
 Hearing loss (HL) hearing loss disorder 2,370,365
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018414/ScoringFiles/PGS018414.txt.gz
PGS018415
(pgscio)
 PGP000832 |
Miao DNR et al. Hum Genomics (2024)
 cisplatin-induced ototoxicity (CIO) ototoxicity,
response to cisplatin		 138,670
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018415/ScoringFiles/PGS018415.txt.gz
PGS018416
(PRS_knee)
 PGP000833 |
Wei Y et al. Clin Nutr (2024)
 Knee osteoarthritis osteoarthritis, knee 83
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018416/ScoringFiles/PGS018416.txt.gz
PGS018417
(PRS_hip)
 PGP000833 |
Wei Y et al. Clin Nutr (2024)
 Hip osteoarthritis osteoarthritis, hip 70
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018417/ScoringFiles/PGS018417.txt.gz
PGS018418
(T2D_GRS)
 PGP000834 |
Wu S et al. Maturitas (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 37
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018418/ScoringFiles/PGS018418.txt.gz
PGS018419
(TPMI_070_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis viral hepatitis 1,584
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018419/ScoringFiles/PGS018419.txt.gz
PGS018420
(TPMI_070_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis viral hepatitis 939,805
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018420/ScoringFiles/PGS018420.txt.gz
PGS018421
(TPMI_070_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis viral hepatitis 49,513
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018421/ScoringFiles/PGS018421.txt.gz
PGS018422
(TPMI_070_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis viral hepatitis 983,768
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018422/ScoringFiles/PGS018422.txt.gz
PGS018423
(TPMI_070_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis viral hepatitis 136,488
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018423/ScoringFiles/PGS018423.txt.gz
PGS018424
(TPMI_070.2_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis B hepatitis B virus infection 4,575
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018424/ScoringFiles/PGS018424.txt.gz
PGS018425
(TPMI_070.2_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis B hepatitis B virus infection 939,797
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018425/ScoringFiles/PGS018425.txt.gz
PGS018426
(TPMI_070.2_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis B hepatitis B virus infection 253,455
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018426/ScoringFiles/PGS018426.txt.gz
PGS018427
(TPMI_070.2_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis B hepatitis B virus infection 983,762
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018427/ScoringFiles/PGS018427.txt.gz
PGS018428
(TPMI_070.2_PRSmix+)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis B hepatitis B virus infection 1,071,340
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018428/ScoringFiles/PGS018428.txt.gz
PGS018429
(TPMI_070.2_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral hepatitis B hepatitis B virus infection 73,098
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018429/ScoringFiles/PGS018429.txt.gz
PGS018430
(TPMI_070.4_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic hepatitis chronic hepatitis 305
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018430/ScoringFiles/PGS018430.txt.gz
PGS018431
(TPMI_070.4_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic hepatitis chronic hepatitis 939,883
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018431/ScoringFiles/PGS018431.txt.gz
PGS018432
(TPMI_070.4_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic hepatitis chronic hepatitis 35,057
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018432/ScoringFiles/PGS018432.txt.gz
PGS018433
(TPMI_070.4_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic hepatitis chronic hepatitis 983,814
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018433/ScoringFiles/PGS018433.txt.gz
PGS018434
(TPMI_070.4_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Chronic hepatitis chronic hepatitis 947,767
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018434/ScoringFiles/PGS018434.txt.gz
PGS018435
(TPMI_070.9_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hepatitis NOS Hepatitis 60
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018435/ScoringFiles/PGS018435.txt.gz
PGS018436
(TPMI_070.9_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hepatitis NOS Hepatitis 182,889
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018436/ScoringFiles/PGS018436.txt.gz
PGS018437
(TPMI_070.9_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hepatitis NOS Hepatitis 27,412
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018437/ScoringFiles/PGS018437.txt.gz
PGS018438
(TPMI_070.9_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hepatitis NOS Hepatitis 983,808
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018438/ScoringFiles/PGS018438.txt.gz
PGS018439
(TPMI_070.9_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Hepatitis NOS Hepatitis 998,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018439/ScoringFiles/PGS018439.txt.gz
PGS018440
(TPMI_078_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral warts HPV common wart 85
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018440/ScoringFiles/PGS018440.txt.gz
PGS018441
(TPMI_078_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral warts HPV common wart 939,884
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018441/ScoringFiles/PGS018441.txt.gz
PGS018442
(TPMI_078_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral warts HPV common wart 21,918
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018442/ScoringFiles/PGS018442.txt.gz
PGS018443
(TPMI_078_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral warts HPV common wart 983,817
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018443/ScoringFiles/PGS018443.txt.gz
PGS018444
(TPMI_078_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Viral warts HPV common wart 978,577
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018444/ScoringFiles/PGS018444.txt.gz
PGS018445
(TPMI_110.11_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 39,561
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018445/ScoringFiles/PGS018445.txt.gz
PGS018446
(TPMI_110.11_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 350,151
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018446/ScoringFiles/PGS018446.txt.gz
PGS018447
(TPMI_110.11_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 16,307
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018447/ScoringFiles/PGS018447.txt.gz
PGS018448
(TPMI_110.11_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 983,814
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018448/ScoringFiles/PGS018448.txt.gz
PGS018449
(TPMI_110.11_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of nail tinea unguium 977,859
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018449/ScoringFiles/PGS018449.txt.gz
PGS018450
(TPMI_110.13_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 54
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018450/ScoringFiles/PGS018450.txt.gz
PGS018451
(TPMI_110.13_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 939,803
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018451/ScoringFiles/PGS018451.txt.gz
PGS018452
(TPMI_110.13_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 605,197
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018452/ScoringFiles/PGS018452.txt.gz
PGS018453
(TPMI_110.13_PRS-CS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 983,765
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018453/ScoringFiles/PGS018453.txt.gz
PGS018454
(TPMI_110.13_SBayesR)
 PGP000835 |
Chen HH et al. Nature (2025)
 Dermatophytosis of the body dermatophytosis 1,012,332
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018454/ScoringFiles/PGS018454.txt.gz
PGS018455
(TPMI_145_Lassosum2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Oral cavity cancer oral cavity cancer 1,019
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018455/ScoringFiles/PGS018455.txt.gz
PGS018456
(TPMI_145_LDpred2)
 PGP000835 |
Chen HH et al. Nature (2025)
 Oral cavity cancer oral cavity cancer 939,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018456/ScoringFiles/PGS018456.txt.gz
PGS018457
(TPMI_145_MegaPRS)
 PGP000835 |
Chen HH et al. Nature (2025)
 Oral cavity cancer oral cavity cancer 17,831
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018457/ScoringFiles/PGS018457.txt.gz
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