Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004874
(INTERVENE_MegaPRS_T1D)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Type 1 diabetes (T1D) type 1 diabetes mellitus 56,916
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004874/ScoringFiles/PGS004874.txt.gz
PGS004875
(INTERVENE_MegaPRS_AllCancers)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 All Cancers cancer 818,872
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004875/ScoringFiles/PGS004875.txt.gz
PGS004876
(INTERVENE_MegaPRS_Appendicitis)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Appendicitis appendicitis 601,835
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004876/ScoringFiles/PGS004876.txt.gz
PGS004877
(INTERVENE_MegaPRS_Asthma)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Asthma asthma 870,454
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004877/ScoringFiles/PGS004877.txt.gz
PGS004878
(INTERVENE_MegaPRS_Atrial_fibrillation)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Atrial fibrillation atrial fibrillation 785,779
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004878/ScoringFiles/PGS004878.txt.gz
PGS004879
(INTERVENE_MegaPRS_CHD)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Coronary heart disease coronary artery disease 610,677
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004879/ScoringFiles/PGS004879.txt.gz
PGS004880
(INTERVENE_MegaPRS_Colorectal_cancer)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Colorectal cancer colorectal carcinoma 843,248
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004880/ScoringFiles/PGS004880.txt.gz
PGS004881
(INTERVENE_MegaPRS_Epilepsy)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Epilepsy epilepsy 605,432
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004881/ScoringFiles/PGS004881.txt.gz
PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Hip osteoarthritis osteoarthritis, hip 773,587
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004882/ScoringFiles/PGS004882.txt.gz
PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Knee osteoarthritis osteoarthritis, knee 952,133
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004883/ScoringFiles/PGS004883.txt.gz
PGS004884
(INTERVENE_MegaPRS_Lung_cancer)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Lung cancer lung carcinoma 655,479
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004884/ScoringFiles/PGS004884.txt.gz
PGS004885
(INTERVENE_MegaPRS_MDD)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Major depressive disorder major depressive disorder 801,544
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004885/ScoringFiles/PGS004885.txt.gz
PGS004886
(INTERVENE_MegaPRS_Melanoma)
 PGP000618 |
Jermy B et al. Nat Commun (2024)
 Melanoma melanoma 692,834
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004886/ScoringFiles/PGS004886.txt.gz
PGS004887
(T2D_gePGS)
 PGP000619 |
Mandla R et al. Genome Med (2024)
 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,117,628
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004887/ScoringFiles/PGS004887.txt.gz
PGS004888
(CAD_gePGS)
 PGP000619 |
Mandla R et al. Genome Med (2024)
 Coronary artery diseae coronary artery disease 1,110,046
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004888/ScoringFiles/PGS004888.txt.gz
PGS004889
(CKD_gePGS)
 PGP000619 |
Mandla R et al. Genome Med (2024)
 Chronic kidney disease chronic kidney disease 1,117,375
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004889/ScoringFiles/PGS004889.txt.gz
PGS004890
(CC-GWAS_PRS)
 PGP000620 |
Sun X et al. Cancer Res (2024)
 Triple negative breast cancer versus luminal breast cancer triple-negative breast cancer 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004890/ScoringFiles/PGS004890.txt.gz
PGS004891
(TNBC_PRS25)
 PGP000620 |
Sun X et al. Cancer Res (2024)
 Triple negative breast cancer triple-negative breast cancer 25
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004891/ScoringFiles/PGS004891.txt.gz
PGS004892
(TNBC_PRS41)
 PGP000620 |
Sun X et al. Cancer Res (2024)
 Triple negative breast cancer triple-negative breast cancer 41
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004892/ScoringFiles/PGS004892.txt.gz
PGS004893
(overall.hybrid.prs)
 PGP000621 |
Gao G et al. Hum Mol Genet (2022)
 Breast cancer breast carcinoma 56,943
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004893/ScoringFiles/PGS004893.txt.gz
PGS004894
(ERpos.prs)
 PGP000621 |
Gao G et al. Hum Mol Genet (2022)
 Estrogen receptor positive breast cancer estrogen-receptor positive breast cancer 29,309
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004894/ScoringFiles/PGS004894.txt.gz
PGS004895
(ERneg.prs)
 PGP000621 |
Gao G et al. Hum Mol Genet (2022)
 Estrogen receptor negative breast cancer estrogen-receptor negative breast cancer 28,405
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004895/ScoringFiles/PGS004895.txt.gz
PGS004896
(mAlb)
 PGP000623 |
Cañadas-Garre M et al. Int J Mol Sci (2023)
 Microalbuminuria Moderate albuminuria 29
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004896/ScoringFiles/PGS004896.txt.gz
PGS004897
(UACR)
 PGP000623 |
Cañadas-Garre M et al. Int J Mol Sci (2023)
 Urinary albumin-to-creatinine ratio urinary albumin to creatinine ratio 28
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004897/ScoringFiles/PGS004897.txt.gz
PGS004898
(PRS_AD)
 PGP000624 |
Vasiljevic E et al. Alzheimers Dement (2023)
 Alzheimer's disease Alzheimer disease 44
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004898/ScoringFiles/PGS004898.txt.gz
PGS004899
(PRS_SCAD)
 PGP000629 |
Saw J et al. Nat Commun (2020)
 Spontaneous coronary artery dissection spontaneous coronary artery dissection 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004899/ScoringFiles/PGS004899.txt.gz
PGS004900
(GRS_BMI_males)
 PGP000630 |
Wu Y et al. PLoS Genet (2020)
 Body mass index (BMI) body mass index 94
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004900/ScoringFiles/PGS004900.txt.gz
PGS004901
(GRS_BMI_females)
 PGP000630 |
Wu Y et al. PLoS Genet (2020)
 Body mass index (BMI) body mass index 94
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004901/ScoringFiles/PGS004901.txt.gz
PGS004902
(PRSBMI)
 PGP000631 |
Chikowore T et al. Genome Med (2024)
 Body mass index (BMI) body mass index 322,639
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004902/ScoringFiles/PGS004902.txt.gz
PGS004903
(PRS_ALL)
 PGP000633 |
Al-Janabi A et al. J Allergy Clin Immunol (2023)
 Atopic dermatitis atopic eczema 38
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004903/ScoringFiles/PGS004903.txt.gz
PGS004904
(PRS127_CRC)
 PGP000636 |
Jiang F et al. Int J Cancer (2023)
 Colorectal cancer colorectal carcinoma 127
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004904/ScoringFiles/PGS004904.txt.gz
PGS004905
(PRS155_AF)
 PGP000638 |
Ma Y et al. Proc Natl Acad Sci U S A (2023)
 Atrial fibrillation atrial fibrillation 155
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004905/ScoringFiles/PGS004905.txt.gz
PGS004906
(PRS60_TSH)
 PGP000639 |
Mulder TA et al. Eur J Endocrinol (2023)
 Thyroid stimulating hormone concentration thyroid stimulating hormone measurement 60
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004906/ScoringFiles/PGS004906.txt.gz
PGS004907
(PRS31_FT4)
 PGP000639 |
Mulder TA et al. Eur J Endocrinol (2023)
 Free thyroxine concentration thyroxine measurement 31
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004907/ScoringFiles/PGS004907.txt.gz
PGS004908
(PRS107_KC)
 PGP000640 |
Purdue MP et al. Nat Genet (2024)
 Kidney cancer renal carcinoma 107
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004908/ScoringFiles/PGS004908.txt.gz
PGS004909
(EUR_wGRS7)
 PGP000641 |
El-Boraie A et al. Addict Biol (2019)
 Nicotine metabolite ratio nicotine metabolite ratio 7
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004909/ScoringFiles/PGS004909.txt.gz
PGS004912
(PRS183)
 PGP000643 |
Tian J et al. Genome Med (2024)
 Colorectal neoplasm colorectal carcinoma 183
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004912/ScoringFiles/PGS004912.txt.gz
PGS004913
(PRSALC)
 PGP000645 |
Schwantes-An TH et al. Hepatol Commun (2024)
 Alcohol-associated liver cirrhosis alcoholic liver cirrhosis 20
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004913/ScoringFiles/PGS004913.txt.gz
PGS004914
(HDL-C_PGS)
 PGP000647 |
Trinder M et al. Arterioscler Thromb Vasc Biol (2019)
 HDL cholesterol high density lipoprotein cholesterol measurement 223
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004914/ScoringFiles/PGS004914.txt.gz
PGS004915
(LDL-C_PGS)
 PGP000647 |
Trinder M et al. Arterioscler Thromb Vasc Biol (2019)
 LDL cholesterol low density lipoprotein cholesterol measurement 223
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004915/ScoringFiles/PGS004915.txt.gz
PGS004916
(Triglycerides_PGS)
 PGP000647 |
Trinder M et al. Arterioscler Thromb Vasc Biol (2019)
 Triglycerides triglyceride measurement 223
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004916/ScoringFiles/PGS004916.txt.gz
PGS004917
(wGRS)
 PGP000648 |
Cui J et al. Arthritis Rheumatol (2020)
 Systemic lupus erythematosus systemic lupus erythematosus 97
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004917/ScoringFiles/PGS004917.txt.gz
PGS004918
(PRS8_Synapse)
 PGP000649 |
Lawingco T et al. Neurobiol Aging (2020)
 Late-onset Alzheimers disease (based on SNPs in genes involved in synaptic function) late-onset Alzheimer's disease 8
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004918/ScoringFiles/PGS004918.txt.gz
PGS004919
(CAD_GRS_50)
 PGP000650 |
Sjögren M et al. Int J Cardiol Heart Vasc (2019)
 Coronary artery disease coronary artery disease 50
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004919/ScoringFiles/PGS004919.txt.gz
PGS004920
(GRS166_AF)
 PGP000652 |
Wang N et al. Eur Heart J (2021)
 Atrial fibrillation atrial fibrillation 166
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004920/ScoringFiles/PGS004920.txt.gz
PGS004921
(CAD-GRS)
 PGP000654 |
Huang Y et al. Circ Genom Precis Med (2020)
 Coronary artery disease coronary artery disease 161
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004921/ScoringFiles/PGS004921.txt.gz
PGS004922
(wGRS_AFR)
 PGP000655 |
El-Boraie A et al. Clin Pharmacol Ther (2021)
 Nicotine metabolite ratio nicotine metabolite ratio 14
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004922/ScoringFiles/PGS004922.txt.gz
PGS004923
(T2D_metaGRS)
 PGP000656 |
Ritchie SC et al. medRxiv (2024)
|Pre		 Type 2 diabetes (T2D) type 2 diabetes mellitus 1,349,896
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004923/ScoringFiles/PGS004923.txt.gz
PGS004924
(PRS90_PD)
 PGP000657 |
Cao Z et al. Parkinsonism Relat Disord (2023)
 Parkinson's disease Parkinson disease 90
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004924/ScoringFiles/PGS004924.txt.gz
PGS004925
(PRS300_CHD)
 PGP000660 |
Kim Y et al. J Intern Med (2023)
 Coronary heart disease coronary artery disease 300
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004925/ScoringFiles/PGS004925.txt.gz
Showing 4801 to 4850 of 5001 rows