| Publication Information (EuropePMC) | |
| Title | Genetic risk and polygenic risk score assessment of prediabetes and progression to type 2 diabetes. |
| PubMed ID | 40468860(Europe PMC) |
| doi | 10.1111/dom.16490 |
| Publication Date | June 5, 2025 |
| Journal | Diabetes Obes Metab |
| Author(s) | Aliyu U, Umlai UI, Al-Thani NM, Toor SM, Abou-Samra AB, Albagha OME. |
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS004615 (PGS_weights_TMM_All_of_1group) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 855,161 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004615/ScoringFiles/PGS004615.txt.gz |
| PGS004616 (PGS_weights_TMM_HighBMI_of_2groups) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 855,161 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004616/ScoringFiles/PGS004616.txt.gz |
| PGS004617 (PGS_weights_TMM_LowBMI_of_2groups) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 855,161 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004617/ScoringFiles/PGS004617.txt.gz |
| PGS004106 (pt_clump.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 35 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004106/ScoringFiles/PGS004106.txt.gz | |
| PGS004619 (PGS_weights_BBJ2nd_HighBMI_of_2groups) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 728,824 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004619/ScoringFiles/PGS004619.txt.gz |
| PGS004620 (PGS_weights_BBJ2nd_LowBMI_of_2groups) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 728,824 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004620/ScoringFiles/PGS004620.txt.gz |
| PGS004618 (PGS_weights_BBJ2nd_All_of_1group) |
PGP000593 | Ojima T et al. Nat Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 728,824 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004618/ScoringFiles/PGS004618.txt.gz |
| PGS000014 (GPS_T2D) |
PGP000006 | Khera AV et al. Nat Genet (2018) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,917,436 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000014/ScoringFiles/PGS000014.txt.gz | |
| PGS003089 (ExPRSweb_T2D_2443_LASSOSUM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 488,969 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003089/ScoringFiles/PGS003089.txt.gz | |
| PGS003090 (ExPRSweb_T2D_2443_PT_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,888 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003090/ScoringFiles/PGS003090.txt.gz | |
| PGS003091 (ExPRSweb_T2D_2443_PLINK_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 2,707 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003091/ScoringFiles/PGS003091.txt.gz | |
| PGS000020 (dGRS1000) |
PGP000010 | Läll K et al. Genet Med (2016) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 7,502 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000020/ScoringFiles/PGS000020.txt.gz |
| PGS003093 (ExPRSweb_T2D_2443_PRSCS_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,113,832 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003093/ScoringFiles/PGS003093.txt.gz | |
| PGS003094 (ExPRSweb_T2D_29358691-GCST005413_LASSOSUM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 266,890 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003094/ScoringFiles/PGS003094.txt.gz | |
| PGS003095 (ExPRSweb_T2D_29358691-GCST005413_PT_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 45 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003095/ScoringFiles/PGS003095.txt.gz | |
| PGS003096 (ExPRSweb_T2D_29358691-GCST005413_PLINK_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 46 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003096/ScoringFiles/PGS003096.txt.gz | |
| PGS003092 (ExPRSweb_T2D_2443_DBSLMM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 10,304,000 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003092/ScoringFiles/PGS003092.txt.gz | |
| PGS004122 (pt_clump_nested.CV.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 297 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004122/ScoringFiles/PGS004122.txt.gz | |
| PGS003099 (ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 555,512 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003099/ScoringFiles/PGS003099.txt.gz | |
| PGS003100 (ExPRSweb_T2D_30054458-GCST006867_PT_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,693 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003100/ScoringFiles/PGS003100.txt.gz | |
| PGS003101 (ExPRSweb_T2D_30054458-GCST006867_PLINK_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,693 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003101/ScoringFiles/PGS003101.txt.gz | |
| PGS003102 (ExPRSweb_T2D_30054458-GCST006867_DBSLMM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,052,574 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003102/ScoringFiles/PGS003102.txt.gz | |
| PGS000031 (GRSt) |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 62 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000031/ScoringFiles/PGS000031.txt.gz |
| PGS000032 (GRSB) |
PGP000020 | Vassy JL et al. Diabetes (2014) |
Type 2 diabetes (based on SNPs involved in β-cell function) | type 2 diabetes mellitus | 20 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000032/ScoringFiles/PGS000032.txt.gz |
| PGS003103 (ExPRSweb_T2D_30054458-GCST006867_PRSCS_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 945,820 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003103/ScoringFiles/PGS003103.txt.gz | |
| PGS003104 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 374,510 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003104/ScoringFiles/PGS003104.txt.gz | |
| PGS003106 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 187 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003106/ScoringFiles/PGS003106.txt.gz | |
| PGS003108 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,118,480 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003108/ScoringFiles/PGS003108.txt.gz | |
| PGS003109 (ExPRSweb_T2D_29358691-GCST005413_LASSOSUM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 311,565 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003109/ScoringFiles/PGS003109.txt.gz | |
| PGS003110 (ExPRSweb_T2D_29358691-GCST005413_PT_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 118 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003110/ScoringFiles/PGS003110.txt.gz | |
| PGS003111 (ExPRSweb_T2D_29358691-GCST005413_PLINK_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 143 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003111/ScoringFiles/PGS003111.txt.gz | |
| PGS003105 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_MGI_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 187 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003105/ScoringFiles/PGS003105.txt.gz | |
| PGS004136 (sbayesr.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 930,497 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004136/ScoringFiles/PGS004136.txt.gz | |
| PGS003114 (ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 555,528 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003114/ScoringFiles/PGS003114.txt.gz | |
| PGS003115 (ExPRSweb_T2D_30054458-GCST006867_PT_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 31,462 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003115/ScoringFiles/PGS003115.txt.gz | |
| PGS003116 (ExPRSweb_T2D_30054458-GCST006867_PLINK_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 31,462 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003116/ScoringFiles/PGS003116.txt.gz | |
| PGS003117 (ExPRSweb_T2D_30054458-GCST006867_DBSLMM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,052,993 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003117/ScoringFiles/PGS003117.txt.gz | |
| PGS003118 (ExPRSweb_T2D_30054458-GCST006867_PRSCS_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 945,921 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003118/ScoringFiles/PGS003118.txt.gz | |
| PGS003119 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 407,553 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003119/ScoringFiles/PGS003119.txt.gz | |
| PGS003120 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 193 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003120/ScoringFiles/PGS003120.txt.gz | |
| PGS003121 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 193 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003121/ScoringFiles/PGS003121.txt.gz | |
| PGS003113 (ExPRSweb_T2D_29358691-GCST005413_PRSCS_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,117,087 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003113/ScoringFiles/PGS003113.txt.gz | |
| PGS003123 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_UKB_20211120) |
PGP000393 | Ma Y et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,119,522 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003123/ScoringFiles/PGS003123.txt.gz | |
| PGS004152 (UKBB_EnsPGS.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,071,786 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004152/ScoringFiles/PGS004152.txt.gz | |
| PGS004181 (t2d_1) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 10,202 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004181/ScoringFiles/PGS004181.txt.gz |
| PGS004182 (t2d_2) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 10,778 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004182/ScoringFiles/PGS004182.txt.gz |
| PGS004183 (t2d_3) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 8,154 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004183/ScoringFiles/PGS004183.txt.gz |
| PGS004184 (t2d_4) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 9,645 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004184/ScoringFiles/PGS004184.txt.gz |
| PGS004185 (t2d_5) |
PGP000520 | Raben TG et al. Sci Rep (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 3,277 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004185/ScoringFiles/PGS004185.txt.gz |
| PGS002671 (disease_T2D.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 258,382 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002671/ScoringFiles/PGS002671.txt.gz |
| PGS000125 (Qi_T2D_2017) |
PGP000062 | Qi Q et al. Diabetes (2017) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 80 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000125/ScoringFiles/PGS000125.txt.gz |
| PGS004223 (PRS139_T2D) |
PGP000523 | Lin J et al. Sci Total Environ (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 139 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004223/ScoringFiles/PGS004223.txt.gz |
| PGS004226 (PRS50_T2DEur) |
PGP000526 | Liu J et al. Nutrients (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 50 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004226/ScoringFiles/PGS004226.txt.gz |
| PGS003728 (PS_T2D_183-AGEN) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 183 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003728/ScoringFiles/PGS003728.txt.gz |
| PGS003729 (PS_T2D_293-DIAGRAM) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 293 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003729/ScoringFiles/PGS003729.txt.gz |
| PGS003730 (PS_T2D_287-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003730/ScoringFiles/PGS003730.txt.gz |
| PGS003731 (PS_T2D_282-SAS-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 282 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003731/ScoringFiles/PGS003731.txt.gz |
| PGS003732 (PS_T2D_287-HIS-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003732/ScoringFiles/PGS003732.txt.gz |
| PGS003733 (PS_T2D_287-EUR-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003733/ScoringFiles/PGS003733.txt.gz |
| PGS003734 (PS_T2D_280-EAS-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 280 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003734/ScoringFiles/PGS003734.txt.gz |
| PGS003735 (PS_T2D_276-AFR-DIAMANTE) |
PGP000469 | Wedekind LE et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 276 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003735/ScoringFiles/PGS003735.txt.gz |
| PGS002720 (disease_T2D.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 911,809 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002720/ScoringFiles/PGS002720.txt.gz |
| PGS003751 (ModelT2D_over45) |
PGP000472 | Shoaib M et al. Genet Epidemiol (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 354 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003751/ScoringFiles/PGS003751.txt.gz | |
| PGS003752 (ModelT2D) |
PGP000472 | Shoaib M et al. Genet Epidemiol (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 333 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003752/ScoringFiles/PGS003752.txt.gz | |
| PGS002733 (GRS17_T2D) |
PGP000342 | Pezzilli S et al. Diabetes Metab (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 17 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002733/ScoringFiles/PGS002733.txt.gz |
| PGS002243 (ldpred_t2d) |
PGP000271 | Mars N et al. Cell Genom (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,431,973 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002243/ScoringFiles/PGS002243.txt.gz | |
| PGS000712 (T2D_HbA1c_39) |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
T2D (cases vs HbA1c filtered controls) | type 2 diabetes mellitus | 183,695 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000712/ScoringFiles/PGS000712.txt.gz |
| PGS000713 (T2D) |
PGP000128 | Sinnott-Armstrong N et al. Nat Genet (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 183,830 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000713/ScoringFiles/PGS000713.txt.gz |
| PGS002771 (Type_2_diabetes_prscs) |
PGP000364 | Mars N et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,091,608 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002771/ScoringFiles/PGS002771.txt.gz |
| PGS004310 (GenoBoost_type_2_diabetes_0) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 7,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004310/ScoringFiles/PGS004310.txt.gz |
| PGS004311 (GenoBoost_type_2_diabetes_1) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 4,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004311/ScoringFiles/PGS004311.txt.gz |
| PGS004312 (GenoBoost_type_2_diabetes_2) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 7,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004312/ScoringFiles/PGS004312.txt.gz |
| PGS004313 (GenoBoost_type_2_diabetes_3) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 8,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004313/ScoringFiles/PGS004313.txt.gz |
| PGS004314 (GenoBoost_type_2_diabetes_4) |
PGP000546 | Ohta R et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,000 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004314/ScoringFiles/PGS004314.txt.gz |
| PGS002779 (GTG_T2D_maxCT) |
PGP000365 | Wong CK et al. PLoS One (2022) |
Incident type 2 diabetes | type 2 diabetes mellitus | 46,353 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002779/ScoringFiles/PGS002779.txt.gz | |
| PGS002780 (GTG_T2D_SCT) |
PGP000365 | Wong CK et al. PLoS One (2022) |
Incident type 2 diabetes | type 2 diabetes mellitus | 419,209 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002780/ScoringFiles/PGS002780.txt.gz | |
| PGS004323 (PRS91_T2D) |
PGP000557 | Tan Q et al. J Hazard Mater (2023) |
Type 2 diabetes | type 2 diabetes mellitus | 91 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004323/ScoringFiles/PGS004323.txt.gz |
| PGS004837 (t2d_PRSmix_eur) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 3,306,136 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004837/ScoringFiles/PGS004837.txt.gz |
| PGS004838 (t2d_PRSmix_sas) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,586,458 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004838/ScoringFiles/PGS004838.txt.gz |
| PGS004839 (t2d_PRSmixPlus_eur) |
PGP000604 | Truong B et al. Cell Genom (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 4,594,694 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004839/ScoringFiles/PGS004839.txt.gz |
| PGS001781 (T2D_PRSCS) |
PGP000261 | Tamlander M et al. Commun Biol (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,091,673 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001781/ScoringFiles/PGS001781.txt.gz |
| PGS004859 (T2D_PRS_CS) |
PGP000605 | Deutsch AJ et al. Diabetes Care (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,108,235 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004859/ScoringFiles/PGS004859.txt.gz |
| PGS002308 (PRScsx_T2D) |
PGP000331 | Ge T et al. Genome Med (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,259,754 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002308/ScoringFiles/PGS002308.txt.gz |
| PGS004868 (T2DPGS) |
PGP000617 | Yun JS et al. Cardiovasc Diabetol (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,580,804 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004868/ScoringFiles/PGS004868.txt.gz |
| PGS004870 (INTERVENE_MegaPRS_T2D) |
PGP000618 | Jermy B et al. Nat Commun (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 930,506 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004870/ScoringFiles/PGS004870.txt.gz | |
| PGS001294 (GBE_HC649) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Non-insulin-dependent diabetes (time-to-event) | type 2 diabetes mellitus | 3,496 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001294/ScoringFiles/PGS001294.txt.gz |
| PGS004887 (T2D_gePGS) |
PGP000619 | Mandla R et al. Genome Med (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,117,628 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004887/ScoringFiles/PGS004887.txt.gz | |
| PGS003353 (GRS_T2D) |
PGP000405 | Kim YJ et al. Nat Commun (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 287 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003353/ScoringFiles/PGS003353.txt.gz |
| PGS001818 (portability-PLR_250.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 30,745 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001818/ScoringFiles/PGS001818.txt.gz |
| PGS003867 (T2D_PRScs_ARB) |
PGP000501 | Shim I et al. Nature Communications (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,068,166 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003867/ScoringFiles/PGS003867.txt.gz |
| PGS000804 (GRS582_T2Dmulti) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000804/ScoringFiles/PGS000804.txt.gz |
| PGS000805 (GRS582_T2Deur) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000805/ScoringFiles/PGS000805.txt.gz |
| PGS000806 (GRS582_T2Dafr) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000806/ScoringFiles/PGS000806.txt.gz |
| PGS000807 (GRS582_T2Dasn) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000807/ScoringFiles/PGS000807.txt.gz |
| PGS000808 (GRS582_T2Dhis) |
PGP000193 | Polfus LM et al. HGG Adv (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 582 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000808/ScoringFiles/PGS000808.txt.gz |
| PGS002354 (disease_T2D.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002354/ScoringFiles/PGS002354.txt.gz |
| PGS000832 (T2D-GRS) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 384 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000832/ScoringFiles/PGS000832.txt.gz |
| PGS000330 (PRS_T2D) |
PGP000100 | Mars N et al. Nat Med (2020) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,437,380 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000330/ScoringFiles/PGS000330.txt.gz | |
| PGS003402 (PRS_T2D) |
PGP000419 | Lamri A et al. Elife (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 6,838 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003402/ScoringFiles/PGS003402.txt.gz | |
| PGS002379 (disease_T2D.BOLT-LMM-BBJ) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 920,930 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002379/ScoringFiles/PGS002379.txt.gz |
| PGS001357 (T2D_AnnoPred_PRS) |
PGP000252 | Ye Y et al. Circ Genom Precis Med (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 2,996,761 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001357/ScoringFiles/PGS001357.txt.gz | |
| PGS000852 (T2D_Insulin_Secretion_1) |
PGP000211 | Aly DM et al. Nat Genet (2021) |
Type 2 diabetes (based on SNPs associated with insulin secretion) | type 2 diabetes mellitus | 8 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000852/ScoringFiles/PGS000852.txt.gz |
| PGS000868 (T2D_221) |
PGP000214 | Aksit MA et al. J Clin Endocrinol Metab (2020) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 221 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000868/ScoringFiles/PGS000868.txt.gz |
| PGS003443 (PRScsx_T2D_LAT_EURweights) |
PGP000445 | Huerta-Chagoya A et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,092,496 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003443/ScoringFiles/PGS003443.txt.gz | |
| PGS003444 (PRScsx_T2D_LAT_EASweights) |
PGP000445 | Huerta-Chagoya A et al. Diabetologia (2023) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,001,579 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003444/ScoringFiles/PGS003444.txt.gz | |
| PGS003982 (dbslmm.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,071,764 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003982/ScoringFiles/PGS003982.txt.gz | |
| PGS003998 (lassosum.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 5,548 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003998/ScoringFiles/PGS003998.txt.gz | |
| PGS004014 (lassosum.CV.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 95,649 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004014/ScoringFiles/PGS004014.txt.gz | |
| PGS004024 (ldpred2.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 958,046 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004024/ScoringFiles/PGS004024.txt.gz | |
| PGS004039 (ldpred2.CV.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 958,046 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004039/ScoringFiles/PGS004039.txt.gz | |
| PGS004052 (megaprs.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 800,598 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004052/ScoringFiles/PGS004052.txt.gz | |
| PGS004569 (meta.T2D.score) |
PGP000561 | Jung H et al. Commun Biol (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,059,939 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004569/ScoringFiles/PGS004569.txt.gz |
| PGS004068 (megaprs.CV.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 800,598 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004068/ScoringFiles/PGS004068.txt.gz | |
| PGS002026 (portability-ldpred2_250.2) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 830,783 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002026/ScoringFiles/PGS002026.txt.gz |
| PGS004082 (prscs.auto.GCST004773.T2D) |
PGP000517 | Monti R et al. Am J Hum Genet (2024) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 1,043,329 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004082/ScoringFiles/PGS004082.txt.gz | |
| PGS004602 (PRS424_T2D) |
PGP000580 | Zhuang P et al. Diabetes Care (2021) |
Type 2 diabetes (T2D) | type 2 diabetes mellitus | 424 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004602/ScoringFiles/PGS004602.txt.gz |
|
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|---|
| PPM022838 | PGS003867 (T2D_PRScs_ARB) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.26 [1.179, 1.348] | AUROC: 0.651 [0.636, 0.667] | R²: 0.088 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022771 | PGS000014 (GPS_T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.157 [1.081, 1.239] | AUROC: 0.644 [0.628, 0.66] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022772 | PGS000020 (dGRS1000) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.169 [1.095, 1.247] | AUROC: 0.646 [0.63, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022773 | PGS000031 (GRSt) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.155 [1.086, 1.229] | AUROC: 0.647 [0.631, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022774 | PGS000032 (GRSB) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.18 [1.109, 1.255] | AUROC: 0.648 [0.632, 0.664] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022775 | PGS000125 (Qi_T2D_2017) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.17 [1.1, 1.245] | AUROC: 0.646 [0.631, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022776 | PGS000330 (PRS_T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.19 [1.105, 1.281] | AUROC: 0.646 [0.63, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022777 | PGS000712 (T2D_HbA1c_39) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.299 [1.218, 1.385] | AUROC: 0.656 [0.64, 0.672] | R²: 0.094 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022778 | PGS000713 (T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.276 [1.197, 1.36] | AUROC: 0.654 [0.638, 0.67] | R²: 0.091 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022779 | PGS000804 (GRS582_T2Dmulti) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.226 [1.152, 1.305] | AUROC: 0.651 [0.635, 0.666] | R²: 0.087 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022780 | PGS000805 (GRS582_T2Deur) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.221 [1.147, 1.3] | AUROC: 0.651 [0.635, 0.666] | R²: 0.087 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022781 | PGS000806 (GRS582_T2Dafr) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.129 [1.061, 1.202] | AUROC: 0.645 [0.629, 0.661] | R²: 0.08 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022782 | PGS000807 (GRS582_T2Dasn) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.164 [1.094, 1.239] | AUROC: 0.646 [0.631, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022783 | PGS000808 (GRS582_T2Dhis) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.196 [1.124, 1.273] | AUROC: 0.648 [0.632, 0.664] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022785 | PGS000868 (T2D_221) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.191 [1.118, 1.268] | AUROC: 0.648 [0.632, 0.664] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022786 | PGS001294 (GBE_HC649) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.194 [1.12, 1.273] | AUROC: 0.648 [0.633, 0.664] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022787 | PGS001357 (T2D_AnnoPred_PRS) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.196 [1.122, 1.274] | AUROC: 0.647 [0.631, 0.663] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022788 | PGS001781 (T2D_PRSCS) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.181 [1.104, 1.263] | AUROC: 0.645 [0.629, 0.661] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022789 | PGS001818 (portability-PLR_250.2) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.181 [1.108, 1.258] | AUROC: 0.648 [0.632, 0.664] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022790 | PGS002026 (portability-ldpred2_250.2) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.184 [1.11, 1.264] | AUROC: 0.648 [0.632, 0.663] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022791 | PGS002243 (ldpred_t2d) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.198 [1.122, 1.28] | AUROC: 0.647 [0.631, 0.662] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022792 | PGS002308 (PRScsx_T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.294 [1.208, 1.387] | AUROC: 0.653 [0.638, 0.669] | R²: 0.091 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022793 | PGS002354 (disease_T2D.BOLT-LMM) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.194 [1.12, 1.273] | AUROC: 0.647 [0.632, 0.663] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022795 | PGS002671 (disease_T2D.PolyFun-pred) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.222 [1.147, 1.301] | AUROC: 0.65 [0.634, 0.666] | R²: 0.086 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022796 | PGS002720 (disease_T2D.SBayesR) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.198 [1.125, 1.277] | AUROC: 0.648 [0.632, 0.664] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022797 | PGS002733 (GRS17_T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.144 [1.075, 1.218] | AUROC: 0.646 [0.63, 0.662] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022798 | PGS002771 (Type_2_diabetes_prscs) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.281 [1.193, 1.375] | AUROC: 0.652 [0.636, 0.668] | R²: 0.089 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022799 | PGS002779 (GTG_T2D_maxCT) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.175 [1.098, 1.257] | AUROC: 0.645 [0.629, 0.661] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022800 | PGS002780 (GTG_T2D_SCT) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.227 [1.149, 1.31] | AUROC: 0.649 [0.633, 0.665] | R²: 0.086 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022801 | PGS003089 (ExPRSweb_T2D_2443_LASSOSUM_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.126 [1.057, 1.2] | AUROC: 0.643 [0.627, 0.659] | R²: 0.079 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022802 | PGS003090 (ExPRSweb_T2D_2443_PT_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.17 [1.1, 1.244] | AUROC: 0.646 [0.63, 0.662] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022804 | PGS003093 (ExPRSweb_T2D_2443_PRSCS_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.137 [1.067, 1.213] | AUROC: 0.644 [0.628, 0.66] | R²: 0.08 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022805 | PGS003095 (ExPRSweb_T2D_29358691-GCST005413_PT_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.164 [1.094, 1.239] | AUROC: 0.646 [0.63, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022806 | PGS003096 (ExPRSweb_T2D_29358691-GCST005413_PLINK_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.164 [1.094, 1.239] | AUROC: 0.646 [0.63, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022807 | PGS003099 (ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.227 [1.147, 1.312] | AUROC: 0.649 [0.633, 0.665] | R²: 0.086 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022808 | PGS003100 (ExPRSweb_T2D_30054458-GCST006867_PT_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.154 [1.08, 1.233] | AUROC: 0.644 [0.628, 0.66] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022809 | PGS003101 (ExPRSweb_T2D_30054458-GCST006867_PLINK_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.154 [1.08, 1.233] | AUROC: 0.644 [0.628, 0.66] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022810 | PGS003102 (ExPRSweb_T2D_30054458-GCST006867_DBSLMM_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.159 [1.084, 1.238] | AUROC: 0.646 [0.63, 0.662] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022811 | PGS003103 (ExPRSweb_T2D_30054458-GCST006867_PRSCS_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.198 [1.119, 1.283] | AUROC: 0.647 [0.631, 0.663] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022812 | PGS003104 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.209 [1.132, 1.291] | AUROC: 0.647 [0.631, 0.663] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022814 | PGS003106 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.158 [1.088, 1.233] | AUROC: 0.646 [0.63, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022815 | PGS003108 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.184 [1.106, 1.267] | AUROC: 0.645 [0.629, 0.661] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022816 | PGS003110 (ExPRSweb_T2D_29358691-GCST005413_PT_UKB_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.209 [1.137, 1.285] | AUROC: 0.65 [0.634, 0.666] | R²: 0.086 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022817 | PGS003111 (ExPRSweb_T2D_29358691-GCST005413_PLINK_UKB_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.185 [1.115, 1.259] | AUROC: 0.649 [0.633, 0.665] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022818 | PGS003117 (ExPRSweb_T2D_30054458-GCST006867_DBSLMM_UKB_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.159 [1.084, 1.238] | AUROC: 0.646 [0.63, 0.662] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022819 | PGS003118 (ExPRSweb_T2D_30054458-GCST006867_PRSCS_UKB_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.193 [1.114, 1.278] | AUROC: 0.646 [0.63, 0.662] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022820 | PGS003119 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_UKB_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.218 [1.14, 1.301] | AUROC: 0.648 [0.632, 0.664] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022821 | PGS003120 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_UKB_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.175 [1.103, 1.251] | AUROC: 0.647 [0.631, 0.663] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022822 | PGS003121 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PLINK_UKB_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.175 [1.103, 1.251] | AUROC: 0.647 [0.631, 0.663] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022824 | PGS003353 (GRS_T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.213 [1.14, 1.291] | AUROC: 0.651 [0.635, 0.667] | R²: 0.086 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022825 | PGS003402 (PRS_T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.138 [1.07, 1.211] | AUROC: 0.644 [0.628, 0.66] | R²: 0.08 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022826 | PGS003443 (PRScsx_T2D_LAT_EURweights) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.277 [1.176, 1.386] | AUROC: 0.648 [0.632, 0.664] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022827 | PGS003444 (PRScsx_T2D_LAT_EASweights) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.25 [1.169, 1.336] | AUROC: 0.649 [0.633, 0.665] | R²: 0.088 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022828 | PGS003728 (PS_T2D_183-AGEN) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.188 [1.117, 1.264] | AUROC: 0.649 [0.633, 0.665] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022829 | PGS003729 (PS_T2D_293-DIAGRAM) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.222 [1.147, 1.301] | AUROC: 0.65 [0.634, 0.666] | R²: 0.087 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022830 | PGS003730 (PS_T2D_287-DIAMANTE) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.201 [1.127, 1.279] | AUROC: 0.65 [0.634, 0.666] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022831 | PGS003731 (PS_T2D_282-SAS-DIAMANTE) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.182 [1.11, 1.259] | AUROC: 0.648 [0.632, 0.664] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022833 | PGS003733 (PS_T2D_287-EUR-DIAMANTE) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.197 [1.124, 1.275] | AUROC: 0.65 [0.634, 0.666] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022834 | PGS003734 (PS_T2D_280-EAS-DIAMANTE) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.123 [1.056, 1.195] | AUROC: 0.645 [0.629, 0.661] | R²: 0.079 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022835 | PGS003735 (PS_T2D_276-AFR-DIAMANTE) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.139 [1.071, 1.212] | AUROC: 0.646 [0.63, 0.662] | R²: 0.08 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022836 | PGS003751 (ModelT2D_over45) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.153 [1.084, 1.226] | AUROC: 0.645 [0.629, 0.661] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022837 | PGS003752 (ModelT2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.151 [1.082, 1.224] | AUROC: 0.645 [0.629, 0.661] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022840 | PGS003998 (lassosum.auto.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.162 [1.09, 1.238] | AUROC: 0.645 [0.629, 0.661] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022841 | PGS004014 (lassosum.CV.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.174 [1.1, 1.253] | AUROC: 0.645 [0.629, 0.661] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022842 | PGS004024 (ldpred2.auto.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.197 [1.122, 1.277] | AUROC: 0.647 [0.631, 0.663] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022843 | PGS004039 (ldpred2.CV.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.196 [1.12, 1.277] | AUROC: 0.647 [0.631, 0.662] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022844 | PGS004052 (megaprs.auto.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.218 [1.141, 1.3] | AUROC: 0.648 [0.632, 0.664] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022845 | PGS004068 (megaprs.CV.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.212 [1.136, 1.294] | AUROC: 0.648 [0.632, 0.664] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022846 | PGS004082 (prscs.auto.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.19 [1.113, 1.272] | AUROC: 0.646 [0.63, 0.662] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022847 | PGS004106 (pt_clump.auto.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.143 [1.073, 1.217] | AUROC: 0.644 [0.628, 0.66] | R²: 0.08 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022848 | PGS004122 (pt_clump_nested.CV.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.175 [1.104, 1.251] | AUROC: 0.645 [0.63, 0.661] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022850 | PGS004152 (UKBB_EnsPGS.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.22 [1.143, 1.303] | AUROC: 0.648 [0.632, 0.664] | R²: 0.086 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022851 | PGS004181 (t2d_1) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.155 [1.085, 1.23] | AUROC: 0.646 [0.63, 0.662] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022852 | PGS004182 (t2d_2) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.172 [1.101, 1.247] | AUROC: 0.646 [0.63, 0.662] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022853 | PGS004183 (t2d_3) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.185 [1.113, 1.261] | AUROC: 0.647 [0.631, 0.663] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022854 | PGS004184 (t2d_4) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.165 [1.095, 1.24] | AUROC: 0.646 [0.63, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022855 | PGS004185 (t2d_5) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.21 [1.137, 1.289] | AUROC: 0.65 [0.634, 0.666] | R²: 0.086 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022856 | PGS004223 (PRS139_T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.131 [1.063, 1.203] | AUROC: 0.646 [0.63, 0.662] | R²: 0.08 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022857 | PGS004226 (PRS50_T2DEur) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.166 [1.097, 1.24] | AUROC: 0.647 [0.631, 0.663] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022858 | PGS004310 (GenoBoost_type_2_diabetes_0) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.173 [1.102, 1.248] | AUROC: 0.647 [0.631, 0.663] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022860 | PGS004312 (GenoBoost_type_2_diabetes_2) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.146 [1.078, 1.218] | AUROC: 0.645 [0.63, 0.661] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022861 | PGS004313 (GenoBoost_type_2_diabetes_3) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.209 [1.134, 1.289] | AUROC: 0.65 [0.634, 0.666] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022862 | PGS004314 (GenoBoost_type_2_diabetes_4) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.136 [1.067, 1.209] | AUROC: 0.645 [0.629, 0.661] | R²: 0.08 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022863 | PGS004569 (meta.T2D.score) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.196 [1.123, 1.274] | AUROC: 0.648 [0.632, 0.663] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022864 | PGS004602 (PRS424_T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.228 [1.153, 1.306] | AUROC: 0.652 [0.637, 0.668] | R²: 0.087 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022865 | PGS004615 (PGS_weights_TMM_All_of_1group) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.256 [1.177, 1.34] | AUROC: 0.652 [0.636, 0.668] | R²: 0.089 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022866 | PGS004616 (PGS_weights_TMM_HighBMI_of_2groups) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.174 [1.104, 1.249] | AUROC: 0.647 [0.631, 0.663] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022867 | PGS004617 (PGS_weights_TMM_LowBMI_of_2groups) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.148 [1.078, 1.222] | AUROC: 0.646 [0.63, 0.661] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022869 | PGS004619 (PGS_weights_BBJ2nd_HighBMI_of_2groups) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.184 [1.113, 1.259] | AUROC: 0.647 [0.631, 0.663] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022870 | PGS004620 (PGS_weights_BBJ2nd_LowBMI_of_2groups) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.135 [1.066, 1.208] | AUROC: 0.644 [0.628, 0.66] | R²: 0.08 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022871 | PGS004837 (t2d_PRSmix_eur) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.306 [1.219, 1.399] | AUROC: 0.654 [0.638, 0.669] | R²: 0.092 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022872 | PGS004838 (t2d_PRSmix_sas) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.374 [1.283, 1.471] | AUROC: 0.659 [0.644, 0.675] | R²: 0.099 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022873 | PGS004839 (t2d_PRSmixPlus_eur) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.187 [1.11, 1.269] | AUROC: 0.647 [0.631, 0.663] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022874 | PGS004859 (T2D_PRS_CS) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.332 [1.238, 1.433] | AUROC: 0.654 [0.638, 0.67] | R²: 0.092 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022875 | PGS004868 (T2DPGS) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.155 [1.081, 1.235] | AUROC: 0.644 [0.628, 0.66] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022876 | PGS004870 (INTERVENE_MegaPRS_T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.271 [1.188, 1.36] | AUROC: 0.653 [0.637, 0.669] | R²: 0.089 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022877 | PGS004887 (T2D_gePGS) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.328 [1.233, 1.429] | AUROC: 0.654 [0.638, 0.67] | R²: 0.092 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022879 | PGS004185 (t2d_5) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.684 [1.462, 1.941] | AUROC: 0.785 [0.754, 0.816] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022880 | PGS000832 (T2D-GRS) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.657 [1.429, 1.921] | AUROC: 0.784 [0.755, 0.813] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022881 | PGS004184 (t2d_4) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.596 [1.386, 1.837] | AUROC: 0.773 [0.74, 0.806] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022882 | PGS004183 (t2d_3) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.578 [1.372, 1.814] | AUROC: 0.777 [0.744, 0.81] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022883 | PGS003099 (ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.623 [1.394, 1.89] | AUROC: 0.772 [0.739, 0.805] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022884 | PGS004181 (t2d_1) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.503 [1.322, 1.709] | AUROC: 0.773 [0.74, 0.806] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022885 | PGS004602 (PRS424_T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.606 [1.383, 1.865] | AUROC: 0.771 [0.738, 0.804] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022886 | PGS002771 (Type_2_diabetes_prscs) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.679 [1.425, 1.977] | AUROC: 0.774 [0.743, 0.805] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022887 | PGS004837 (t2d_PRSmix_eur) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.638 [1.402, 1.915] | AUROC: 0.776 [0.745, 0.807] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022889 | PGS003118 (ExPRSweb_T2D_30054458-GCST006867_PRSCS_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.64 [1.397, 1.925] | AUROC: 0.775 [0.742, 0.808] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022890 | PGS003103 (ExPRSweb_T2D_30054458-GCST006867_PRSCS_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.655 [1.405, 1.949] | AUROC: 0.772 [0.739, 0.805] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022891 | PGS004859 (T2D_PRS_CS) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.67 [1.411, 1.977] | AUROC: 0.773 [0.742, 0.804] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022892 | PGS000868 (T2D_221) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.566 [1.351, 1.816] | AUROC: 0.777 [0.746, 0.808] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022893 | PGS004312 (GenoBoost_type_2_diabetes_2) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.499 [1.311, 1.713] | AUROC: 0.769 [0.736, 0.802] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022894 | PGS003729 (PS_T2D_293-DIAGRAM) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.526 [1.325, 1.757] | AUROC: 0.777 [0.746, 0.808] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022895 | PGS003867 (T2D_PRScs_ARB) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.576 [1.353, 1.837] | AUROC: 0.772 [0.741, 0.803] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022896 | PGS003117 (ExPRSweb_T2D_30054458-GCST006867_DBSLMM_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.588 [1.358, 1.857] | AUROC: 0.768 [0.735, 0.801] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022897 | PGS003102 (ExPRSweb_T2D_30054458-GCST006867_DBSLMM_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.588 [1.358, 1.857] | AUROC: 0.768 [0.735, 0.801] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022898 | PGS001781 (T2D_PRSCS) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.561 [1.341, 1.817] | AUROC: 0.766 [0.733, 0.799] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022900 | PGS004870 (INTERVENE_MegaPRS_T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.56 [1.338, 1.818] | AUROC: 0.771 [0.738, 0.804] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022901 | PGS004313 (GenoBoost_type_2_diabetes_3) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.525 [1.314, 1.77] | AUROC: 0.763 [0.73, 0.796] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022902 | PGS002026 (portability-ldpred2_250.2) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.507 [1.304, 1.741] | AUROC: 0.764 [0.731, 0.797] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022903 | PGS003730 (PS_T2D_287-DIAMANTE) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.5 [1.299, 1.732] | AUROC: 0.767 [0.736, 0.798] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022904 | PGS004839 (t2d_PRSmixPlus_eur) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.55 [1.326, 1.811] | AUROC: 0.767 [0.734, 0.8] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022905 | PGS000020 (dGRS1000) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.522 [1.31, 1.768] | AUROC: 0.771 [0.738, 0.804] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022906 | PGS001357 (T2D_AnnoPred_PRS) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.517 [1.306, 1.761] | AUROC: 0.759 [0.724, 0.794] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022907 | PGS003100 (ExPRSweb_T2D_30054458-GCST006867_PT_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.55 [1.324, 1.815] | AUROC: 0.762 [0.727, 0.797] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022908 | PGS003101 (ExPRSweb_T2D_30054458-GCST006867_PLINK_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.55 [1.324, 1.815] | AUROC: 0.762 [0.727, 0.797] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022910 | PGS003731 (PS_T2D_282-SAS-DIAMANTE) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.499 [1.295, 1.734] | AUROC: 0.764 [0.731, 0.797] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022911 | PGS003998 (lassosum.auto.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.489 [1.29, 1.72] | AUROC: 0.761 [0.728, 0.794] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022912 | PGS004152 (UKBB_EnsPGS.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.504 [1.298, 1.743] | AUROC: 0.763 [0.728, 0.798] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022913 | PGS003093 (ExPRSweb_T2D_2443_PRSCS_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.511 [1.3, 1.757] | AUROC: 0.762 [0.729, 0.795] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022914 | PGS004314 (GenoBoost_type_2_diabetes_4) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.484 [1.284, 1.715] | AUROC: 0.76 [0.727, 0.793] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022915 | PGS003732 (PS_T2D_287-HIS-DIAMANTE) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.491 [1.287, 1.726] | AUROC: 0.761 [0.728, 0.794] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022916 | PGS000031 (GRSt) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.455 [1.266, 1.671] | AUROC: 0.77 [0.737, 0.803] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022917 | PGS000712 (T2D_HbA1c_39) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.473 [1.276, 1.7] | AUROC: 0.769 [0.736, 0.802] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022918 | PGS003353 (GRS_T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.489 [1.285, 1.725] | AUROC: 0.765 [0.73, 0.8] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022920 | PGS004615 (PGS_weights_TMM_All_of_1group) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.501 [1.291, 1.746] | AUROC: 0.768 [0.737, 0.799] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022921 | PGS004039 (ldpred2.CV.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.48 [1.279, 1.712] | AUROC: 0.764 [0.729, 0.799] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022922 | PGS001818 (portability-PLR_250.2) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.449 [1.26, 1.667] | AUROC: 0.765 [0.732, 0.798] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022923 | PGS004310 (GenoBoost_type_2_diabetes_0) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.451 [1.26, 1.672] | AUROC: 0.759 [0.726, 0.792] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022924 | PGS003733 (PS_T2D_287-EUR-DIAMANTE) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.464 [1.266, 1.692] | AUROC: 0.765 [0.732, 0.798] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022925 | PGS004052 (megaprs.auto.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.487 [1.278, 1.729] | AUROC: 0.759 [0.726, 0.792] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022926 | PGS000713 (T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.449 [1.257, 1.67] | AUROC: 0.765 [0.732, 0.798] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022927 | PGS001294 (GBE_HC649) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.472 [1.269, 1.709] | AUROC: 0.763 [0.73, 0.796] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022928 | PGS004068 (megaprs.CV.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.475 [1.27, 1.713] | AUROC: 0.76 [0.727, 0.793] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022929 | PGS004223 (PRS139_T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.449 [1.255, 1.672] | AUROC: 0.768 [0.735, 0.801] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022931 | PGS002720 (disease_T2D.SBayesR) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.45 [1.254, 1.675] | AUROC: 0.766 [0.733, 0.799] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022932 | PGS004182 (t2d_2) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.425 [1.241, 1.637] | AUROC: 0.769 [0.738, 0.8] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022933 | PGS004617 (PGS_weights_TMM_LowBMI_of_2groups) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.454 [1.256, 1.684] | AUROC: 0.762 [0.729, 0.795] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022934 | PGS002243 (ldpred_t2d) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.469 [1.262, 1.71] | AUROC: 0.76 [0.727, 0.793] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022935 | PGS003119 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.445 [1.248, 1.673] | AUROC: 0.756 [0.721, 0.791] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022936 | PGS003728 (PS_T2D_183-AGEN) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.438 [1.243, 1.663] | AUROC: 0.761 [0.726, 0.796] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022937 | PGS003104 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_LASSOSUM_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.444 [1.247, 1.672] | AUROC: 0.756 [0.721, 0.791] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022938 | PGS000804 (GRS582_T2Dmulti) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.442 [1.245, 1.67] | AUROC: 0.761 [0.728, 0.794] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022939 | PGS000852 (T2D_Insulin_Secretion_1) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.411 [1.229, 1.62] | AUROC: 0.765 [0.732, 0.798] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022940 | PGS000805 (GRS582_T2Deur) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.434 [1.239, 1.66] | AUROC: 0.759 [0.726, 0.792] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022942 | PGS003108 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.461 [1.251, 1.707] | AUROC: 0.757 [0.722, 0.792] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022943 | PGS003982 (dbslmm.auto.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.43 [1.233, 1.658] | AUROC: 0.757 [0.722, 0.792] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022944 | PGS003123 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.457 [1.246, 1.704] | AUROC: 0.759 [0.724, 0.794] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022945 | PGS000125 (Qi_T2D_2017) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.411 [1.22, 1.632] | AUROC: 0.761 [0.728, 0.794] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022946 | PGS004014 (lassosum.CV.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.419 [1.224, 1.645] | AUROC: 0.755 [0.72, 0.79] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022947 | PGS004323 (PRS91_T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.402 [1.215, 1.619] | AUROC: 0.764 [0.731, 0.797] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022948 | PGS000032 (GRSB) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.389 [1.207, 1.598] | AUROC: 0.764 [0.731, 0.797] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022949 | PGS003443 (PRScsx_T2D_LAT_EURweights) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.537 [1.278, 1.849] | AUROC: 0.761 [0.728, 0.794] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022950 | PGS002379 (disease_T2D.BOLT-LMM-BBJ) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.372 [1.197, 1.573] | AUROC: 0.755 [0.722, 0.788] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022951 | PGS003114 (ExPRSweb_T2D_30054458-GCST006867_LASSOSUM_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.461 [1.238, 1.724] | AUROC: 0.757 [0.724, 0.79] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022953 | PGS004311 (GenoBoost_type_2_diabetes_1) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.388 [1.2, 1.606] | AUROC: 0.76 [0.727, 0.793] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022954 | PGS004226 (PRS50_T2DEur) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.361 [1.183, 1.565] | AUROC: 0.762 [0.729, 0.795] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022955 | PGS004618 (PGS_weights_BBJ2nd_All_of_1group) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.399 [1.2, 1.631] | AUROC: 0.76 [0.727, 0.793] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022956 | PGS000014 (GPS_T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.414 [1.205, 1.659] | AUROC: 0.756 [0.723, 0.789] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022957 | PGS004868 (T2DPGS) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.397 [1.195, 1.633] | AUROC: 0.755 [0.72, 0.79] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022958 | PGS003089 (ExPRSweb_T2D_2443_LASSOSUM_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.386 [1.19, 1.616] | AUROC: 0.756 [0.721, 0.791] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022959 | PGS003110 (ExPRSweb_T2D_29358691-GCST005413_PT_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.34 [1.168, 1.536] | AUROC: 0.756 [0.723, 0.789] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022960 | PGS002780 (GTG_T2D_SCT) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.362 [1.176, 1.578] | AUROC: 0.75 [0.715, 0.785] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022961 | PGS002733 (GRS17_T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.342 [1.167, 1.543] | AUROC: 0.76 [0.727, 0.793] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022962 | PGS003094 (ExPRSweb_T2D_29358691-GCST005413_LASSOSUM_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.355 [1.172, 1.567] | AUROC: 0.761 [0.728, 0.794] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022964 | PGS003115 (ExPRSweb_T2D_30054458-GCST006867_PT_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.437 [1.206, 1.712] | AUROC: 0.756 [0.721, 0.791] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022965 | PGS003116 (ExPRSweb_T2D_30054458-GCST006867_PLINK_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.437 [1.206, 1.712] | AUROC: 0.756 [0.721, 0.791] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022966 | PGS003109 (ExPRSweb_T2D_29358691-GCST005413_LASSOSUM_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.35 [1.167, 1.562] | AUROC: 0.76 [0.727, 0.793] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022967 | PGS003735 (PS_T2D_276-AFR-DIAMANTE) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.345 [1.162, 1.556] | AUROC: 0.754 [0.721, 0.787] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022968 | PGS004122 (pt_clump_nested.CV.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.317 [1.143, 1.516] | AUROC: 0.755 [0.72, 0.79] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022969 | PGS004106 (pt_clump.auto.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.319 [1.144, 1.521] | AUROC: 0.759 [0.726, 0.792] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022970 | PGS003111 (ExPRSweb_T2D_29358691-GCST005413_PLINK_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.304 [1.137, 1.495] | AUROC: 0.753 [0.72, 0.786] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022971 | PGS003734 (PS_T2D_280-EAS-DIAMANTE) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.305 [1.137, 1.497] | AUROC: 0.753 [0.718, 0.788] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022972 | PGS000808 (GRS582_T2Dhis) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.323 [1.142, 1.532] | AUROC: 0.754 [0.721, 0.787] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022973 | PGS004620 (PGS_weights_BBJ2nd_LowBMI_of_2groups) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.328 [1.144, 1.542] | AUROC: 0.751 [0.718, 0.784] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022784 | PGS000832 (T2D-GRS) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.232 [1.157, 1.312] | AUROC: 0.651 [0.635, 0.667] | R²: 0.088 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022794 | PGS002379 (disease_T2D.BOLT-LMM-BBJ) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.153 [1.085, 1.226] | AUROC: 0.645 [0.629, 0.661] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022803 | PGS003091 (ExPRSweb_T2D_2443_PLINK_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.122 [1.055, 1.192] | AUROC: 0.644 [0.628, 0.66] | R²: 0.079 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022813 | PGS003105 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PT_MGI_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.158 [1.088, 1.233] | AUROC: 0.646 [0.63, 0.662] | R²: 0.082 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022823 | PGS003123 (ExPRSweb_T2D_METAANALYSIS-DIAGRAM_PRSCS_UKB_20211120) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.164 [1.088, 1.246] | AUROC: 0.644 [0.628, 0.66] | R²: 0.081 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022832 | PGS003732 (PS_T2D_287-HIS-DIAMANTE) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.202 [1.129, 1.28] | AUROC: 0.648 [0.632, 0.664] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022839 | PGS003982 (dbslmm.auto.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.199 [1.124, 1.28] | AUROC: 0.647 [0.631, 0.662] | R²: 0.084 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022849 | PGS004136 (sbayesr.auto.GCST004773.T2D) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.207 [1.131, 1.288] | AUROC: 0.648 [0.632, 0.663] | R²: 0.085 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022859 | PGS004311 (GenoBoost_type_2_diabetes_1) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.18 [1.108, 1.257] | AUROC: 0.646 [0.63, 0.662] | R²: 0.083 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022868 | PGS004618 (PGS_weights_BBJ2nd_All_of_1group) |
PSS012080| Greater Middle Eastern Ancestry| 4,534 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Prediabetes | OR: 1.216 [1.141, 1.296] | AUROC: 0.65 [0.634, 0.666] | R²: 0.086 | sex, baseline age, BMI, PCs1-10 | — |
| PPM022878 | PGS004838 (t2d_PRSmix_sas) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.793 [1.534, 2.096] | AUROC: 0.792 [0.763, 0.821] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022888 | PGS002308 (PRScsx_T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.628 [1.391, 1.905] | AUROC: 0.779 [0.748, 0.81] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022899 | PGS004887 (T2D_gePGS) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.619 [1.372, 1.91] | AUROC: 0.772 [0.739, 0.805] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022909 | PGS002671 (disease_T2D.PolyFun-pred) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.521 [1.308, 1.769] | AUROC: 0.77 [0.739, 0.801] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022919 | PGS004024 (ldpred2.auto.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.467 [1.272, 1.69] | AUROC: 0.764 [0.729, 0.799] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022930 | PGS004136 (sbayesr.auto.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.443 [1.251, 1.664] | AUROC: 0.762 [0.729, 0.795] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022941 | PGS002354 (disease_T2D.BOLT-LMM) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.436 [1.239, 1.664] | AUROC: 0.761 [0.728, 0.794] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022952 | PGS004082 (prscs.auto.GCST004773.T2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.414 [1.215, 1.646] | AUROC: 0.757 [0.722, 0.792] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022963 | PGS003113 (ExPRSweb_T2D_29358691-GCST005413_PRSCS_UKB_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.352 [1.17, 1.563] | AUROC: 0.755 [0.72, 0.79] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022974 | PGS003096 (ExPRSweb_T2D_29358691-GCST005413_PLINK_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.321 [1.139, 1.533] | AUROC: 0.759 [0.726, 0.792] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022975 | PGS003751 (ModelT2D_over45) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.297 [1.128, 1.491] | AUROC: 0.755 [0.72, 0.79] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022976 | PGS003092 (ExPRSweb_T2D_2443_DBSLMM_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.287 [1.123, 1.473] | AUROC: 0.756 [0.723, 0.789] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022977 | PGS003752 (ModelT2D) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.296 [1.126, 1.491] | AUROC: 0.755 [0.72, 0.79] | — | sex, baseline age, BMI, PCs1-10 | — |
| PPM022978 | PGS003095 (ExPRSweb_T2D_29358691-GCST005413_PT_MGI_20211120) |
PSS012081| Greater Middle Eastern Ancestry| 2,143 individuals |
PGP000753 | Aliyu U et al. Diabetes Obes Metab (2025) |Ext. |
Reported Trait: Incident T2D in prediabetics | HR: 1.317 [1.134, 1.529] | AUROC: 0.758 [0.725, 0.791] | — | sex, baseline age, BMI, PCs1-10 | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS012080 | age-matched cohort | — | [
|
— | Greater Middle Eastern (Middle Eastern, North African or Persian) (Qatari) |
— | QBB | — |
| PSS012081 | — | Median = 6.0 years | [ ,
54.22 % Male samples |
— | Greater Middle Eastern (Middle Eastern, North African or Persian) (Qatari) |
— | QBB | — |