Polygenic Scores (PGS)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS004574
(meta.Z82.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Z82 (Family history of certain disabilities and chronic diseases leading to disablement) family history 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004574/ScoringFiles/PGS004574.txt.gz
PGS004575
(meta.Z88.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Z88 (Personal history of allergy to drugs, medicaments and biologocal substances) clinical history 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004575/ScoringFiles/PGS004575.txt.gz
PGS004576
(meta.Z92.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Z92 (Personal history of medical treatment) clinical history 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004576/ScoringFiles/PGS004576.txt.gz
PGS004577
(meta.Z95.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Z95 (Presence of cardiac and vascular implants and grafts) medical procedure 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004577/ScoringFiles/PGS004577.txt.gz
PGS004578
(meta.Z96.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Z96 (Presence of other functional implants) medical procedure 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004578/ScoringFiles/PGS004578.txt.gz
PGS004579
(BRCA_PRSCS)
PGP000562 |
Youssef O et al. Lab Invest (2024)
Breast cancer breast carcinoma 1,088,163
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004579/ScoringFiles/PGS004579.txt.gz
PGS004580
(CRC_PRSCS)
PGP000562 |
Youssef O et al. Lab Invest (2024)
Colorectal cancer colorectal carcinoma 1,099,906
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004580/ScoringFiles/PGS004580.txt.gz
PGS004581
(PRCA_PRSCS)
PGP000562 |
Youssef O et al. Lab Invest (2024)
Prostate cancer prostate carcinoma 1,102,292
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004581/ScoringFiles/PGS004581.txt.gz
PGS004582
(PRSice_T1)
PGP000563 |
Yang Z et al. Blood (2023)
Platelet count during the first trimester platelet count 407,667
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004582/ScoringFiles/PGS004582.txt.gz
PGS004583
(PRSice_T2)
PGP000563 |
Yang Z et al. Blood (2023)
Platelet count during the second trimester platelet count 104,759
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004583/ScoringFiles/PGS004583.txt.gz
PGS004584
(PRSice_T3)
PGP000563 |
Yang Z et al. Blood (2023)
Platelet count during the third trimester platelet count 5,597
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004584/ScoringFiles/PGS004584.txt.gz
PGS004585
(PRSice_GT)
PGP000563 |
Yang Z et al. Blood (2023)
Gestational thrombocytopenia Thrombocytopenia 475,029
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004585/ScoringFiles/PGS004585.txt.gz
PGS004587
(PRS23_AD)
PGP000566 |
Gu X et al. Ecotoxicol Environ Saf (2023)
Atopic dermatitis atopic eczema 23
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004587/ScoringFiles/PGS004587.txt.gz
PGS004588
(PRS39_Eur)
PGP000567 |
Jung SH et al. JAMA Netw Open (2022)
Alzheimer's disease Alzheimer disease 39
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004588/ScoringFiles/PGS004588.txt.gz
PGS004589
(PRS80_trans)
PGP000567 |
Jung SH et al. JAMA Netw Open (2022)
Alzheimer's disease Alzheimer disease 80
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004589/ScoringFiles/PGS004589.txt.gz
PGS004590
(PRS363_rand_eff)
PGP000569 |
Lake J et al. Mol Psychiatry (2023)
Alzheimer's disease Alzheimer disease 363
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004590/ScoringFiles/PGS004590.txt.gz
PGS004591
(PRS17_MDD)
PGP000570 |
Li D et al. BMC Med (2023)
Major depressive disorder unipolar depression 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004591/ScoringFiles/PGS004591.txt.gz
PGS004592
(PRS_KC)
PGP000571 |
Liyanage UE et al. J Eur Acad Dermatol Venereol (2022)
Keratinocyte cancer keratinocyte carcinoma 78
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004592/ScoringFiles/PGS004592.txt.gz
PGS004593
(pe)
PGP000574 |
Nurkkala J et al. J Hypertens (2022)
Preeclampsia preeclampsia 1,102,059
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004593/ScoringFiles/PGS004593.txt.gz
PGS004594
(ukb.sbp.female)
PGP000574 |
Nurkkala J et al. J Hypertens (2022)
Systolic blood pressure systolic blood pressure 1,097,355
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004594/ScoringFiles/PGS004594.txt.gz
PGS004595
(PRS_CHD)
PGP000575 |
Oni-Orisan A et al. Clin Pharmacol Ther (2022)
Coronary heart disease coronary artery disease 164
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004595/ScoringFiles/PGS004595.txt.gz
PGS004596
(PRS64_CHD)
PGP000576 |
Peng H et al. Nutrients (2023)
Coronary heart disease coronary artery disease 64
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004596/ScoringFiles/PGS004596.txt.gz
PGS004597
(PRS32_IS)
PGP000576 |
Peng H et al. Nutrients (2023)
Ischemic stroke stroke,
Ischemic stroke
32
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004597/ScoringFiles/PGS004597.txt.gz
PGS004598
(PRS12_HF)
PGP000576 |
Peng H et al. Nutrients (2023)
Heart failure heart failure 12
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004598/ScoringFiles/PGS004598.txt.gz
PGS004599
(PRS102_Pca)
PGP000577 |
Ruan X et al. J Clin Med (2023)
Prostate cancer prostate carcinoma 102
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004599/ScoringFiles/PGS004599.txt.gz
PGS004600
(PRS_AD83)
PGP000578 |
Tomassen J et al. BMC Neurol (2022)
Alzheimer's disease Alzheimer disease 83
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004600/ScoringFiles/PGS004600.txt.gz
PGS004601
(PRS17_Pca)
PGP000579 |
Wu Y et al. Clin Genet (2023)
Prostate cancer prostate carcinoma 17
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004601/ScoringFiles/PGS004601.txt.gz
PGS004602
(PRS424_T2D)
PGP000580 |
Zhuang P et al. Diabetes Care (2021)
Type 2 diabetes (T2D) type 2 diabetes mellitus 424
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004602/ScoringFiles/PGS004602.txt.gz
PGS004603
(SBP-meta-analysis)
PGP000581 |
Keaton JM et al. Nat Genet (2024)
Systolic blood pressure systolic blood pressure 7,356,519
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004603/ScoringFiles/PGS004603.txt.gz
PGS004604
(DBP-meta-analysis)
PGP000581 |
Keaton JM et al. Nat Genet (2024)
Diastolic blood pressure diastolic blood pressure 7,356,519
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004604/ScoringFiles/PGS004604.txt.gz
PGS004605
(PP-meta-analysis)
PGP000581 |
Keaton JM et al. Nat Genet (2024)
Pulse pressure pulse pressure measurement 7,356,519
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004605/ScoringFiles/PGS004605.txt.gz
PGS004606
(AMD-IAMDGC-EUR)
PGP000582 |
Gorman BR et al. medRxiv (2022)
|Pre
Age-related macular degeneration age-related macular degeneration 1,000,946
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004606/ScoringFiles/PGS004606.txt.gz
PGS004607
(AMD-MVP-AFR)
PGP000582 |
Gorman BR et al. medRxiv (2022)
|Pre
Age-related macular degeneration age-related macular degeneration 1,067,520
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004607/ScoringFiles/PGS004607.txt.gz
PGS004608
(neuroticism)
PGP000584 |
Forthman KL et al. J Psychiatr Res (2023)
Neuroticism neuroticism measurement 1,000,537
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004608/ScoringFiles/PGS004608.txt.gz
PGS004609
(adult_BMI)
PGP000585 |
Hawkes G et al. Diabetologia (2023)
Body mass index (BMI) body mass index 1,127
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004609/ScoringFiles/PGS004609.txt.gz
PGS004610
(child_BMI)
PGP000585 |
Hawkes G et al. Diabetologia (2023)
Body mass index (BMI) body mass index 306
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004610/ScoringFiles/PGS004610.txt.gz
PGS004611
(RORP_PRS)
PGP000590 |
Shieh Y et al. NPJ Precis Oncol (2023)
Breast cancer breast carcinoma 76
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004611/ScoringFiles/PGS004611.txt.gz
PGS004612
(PRSECG_AI)
PGP000591 |
Wang X et al. Circ Genom Precis Med (2023)
ECG-AI predicted 5-year risk of atrial fibrillation atrial fibrillation 1,117,399
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004612/ScoringFiles/PGS004612.txt.gz
PGS004613
(PRSCHARGE_AF)
PGP000591 |
Wang X et al. Circ Genom Precis Med (2023)
CHARGE-AF predicted 5-year risk of atrial fibrillation atrial fibrillation 1,117,400
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004613/ScoringFiles/PGS004613.txt.gz
PGS004614
(DivD_SNPWeights)
PGP000592 |
Wu Y et al. Cell Genom (2023)
Diverticular disease diverticular disease 1,082,282
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004614/ScoringFiles/PGS004614.txt.gz
PGS004622
(HDL_AFR_lassosum2)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 15,978
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004622/ScoringFiles/PGS004622.txt.gz
PGS004623
(HDL_AFR_ldpred2)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 1,683,003
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004623/ScoringFiles/PGS004623.txt.gz
PGS004624
(HDL_AFR_PROSPER)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 1,688,569
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004624/ScoringFiles/PGS004624.txt.gz
PGS004625
(HDL_AFR_weighted_lassosum2)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 291,154
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004625/ScoringFiles/PGS004625.txt.gz
PGS004626
(HDL_AFR_weighted_ldpred2)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 1,871,796
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004626/ScoringFiles/PGS004626.txt.gz
PGS004627
(HDL_EAS_lassosum2)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 54,812
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004627/ScoringFiles/PGS004627.txt.gz
PGS004628
(HDL_EAS_ldpred2)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 847,389
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004628/ScoringFiles/PGS004628.txt.gz
PGS004629
(HDL_EAS_PROSPER)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 1,731,178
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004629/ScoringFiles/PGS004629.txt.gz
PGS004630
(HDL_EAS_weighted_lassosum2)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 291,154
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004630/ScoringFiles/PGS004630.txt.gz
PGS004631
(HDL_EAS_weighted_ldpred2)
PGP000595 |
Zhang J et al. Nat Commun (2024)
HDL cholesterol high density lipoprotein cholesterol measurement 1,871,796
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004631/ScoringFiles/PGS004631.txt.gz