Trait: skeletal system disorder

Trait Information
Identifier MONDO_0005172
Description A disease involving the skeletal system.
Trait category
Other trait
Synonyms 5 synonyms
  • disease of skeletal system
  • disease or disorder of skeletal system
  • disorder of skeletal system
  • skeletal system disease
  • skeletal system disease or disorder
Child trait(s) 31 child traits

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Note: This table shows PGS for child terms of "skeletal system disorder" in the EFO hierarchy.
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS000114
(GRS-JIA-20)
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Juvenile Idiopathic Arthritis juvenile idiopathic arthritis 26
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000114/ScoringFiles/PGS000114.txt.gz
PGS000194
(G-PROB_Rapos)
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Rheumatoid arthritis (CCP-negative) ACPA-positive rheumatoid arthritis 114
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000194/ScoringFiles/PGS000194.txt.gz
PGS000195
(G-PROB_Raneg)
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Rheumatoid arthritis (CCP-negative) ACPA-negative rheumatoid arthritis 96
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000195/ScoringFiles/PGS000195.txt.gz
PGS000197
(G-PROB_SpA)
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Spondyloarthroparthy spondyloarthropathy 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000197/ScoringFiles/PGS000197.txt.gz
PGS000198
(G-PROB_PsA)
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Psoriatic arthritis psoriatic arthritis 31
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000198/ScoringFiles/PGS000198.txt.gz
PGS000324
(GRS-JIA-ERA-20)
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Enthesitis-related Juvenile Idiophatic Arthritis enthesitis-related juvenile idiopathic arthritis 138
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000324/ScoringFiles/PGS000324.txt.gz
PGS000325
(GRS-JIA-Oli-20)
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Oligoarthritis Juvenile Idiophatic Arthritis oligoarticular juvenile idiopathic arthritis 21
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000325/ScoringFiles/PGS000325.txt.gz
PGS000326
(GRS-JIA-RFN-20)
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Rheumatoid-factor-negative Polyarthritis (Juvenile Idiophatic Arthritis) rheumatoid factor-negative juvenile idiopathic arthritis 12
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000326/ScoringFiles/PGS000326.txt.gz
PGS000342
(wGRS_PsA)
PGP000111 |
Smith MP et al. J Psoriasis Psoriatic Arthritis (2020)
Psoriatic arthritis psoriatic arthritis 11
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000342/ScoringFiles/PGS000342.txt.gz
PGS000343
(wGRS_PsA_HLA)
PGP000111 |
Smith MP et al. J Psoriasis Psoriatic Arthritis (2020)
Psoriatic arthritis psoriatic arthritis 5
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000343/ScoringFiles/PGS000343.txt.gz
PGS000932
(GBE_HC1248)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Other intervertebral disk disorders (time-to-event) vertebral column disorder 111
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000932/ScoringFiles/PGS000932.txt.gz
PGS000964
(GBE_HC176)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Slipped disc Epiphyses, Slipped 47
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000964/ScoringFiles/PGS000964.txt.gz
PGS000967
(GBE_HC1221)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Coxarthrosis [arthrosis of hip] (time-to-event) osteoarthritis, hip 634
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS000967/ScoringFiles/PGS000967.txt.gz
PGS001110
(GBE_HC1209)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reactive arthropathies (time-to-event) reactive arthritis 6
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001110/ScoringFiles/PGS001110.txt.gz
PGS001135
(GBE_HC78)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Arthritis (nos) arthritic joint disease 1,028
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001135/ScoringFiles/PGS001135.txt.gz
PGS001192
(GBE_HC1222)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Gonarthrosis [arthrosis of knee] (time-to-event) osteoarthritis, knee 4,525
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001192/ScoringFiles/PGS001192.txt.gz
PGS001267
(GBE_HC422)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Ankylosing spondylitis ankylosing spondylitis 10
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001267/ScoringFiles/PGS001267.txt.gz
PGS001268
(GBE_HC1242)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Ankylosing spondylitis (time-to-event) ankylosing spondylitis 10
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001268/ScoringFiles/PGS001268.txt.gz
PGS001273
(GBE_HC22)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Osteoporosis osteoporosis 316
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001273/ScoringFiles/PGS001273.txt.gz
PGS001274
(GBE_HC1268)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Osteoporosis without pathological fracture (time-to-event) osteoporosis 1,270
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001274/ScoringFiles/PGS001274.txt.gz
PGS001287
(GBE_HC91)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Psoriatic arthropathy psoriatic arthritis 36
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001287/ScoringFiles/PGS001287.txt.gz
PGS001290
(GBE_HC376)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Osteoarthritis osteoarthritis 579
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001290/ScoringFiles/PGS001290.txt.gz
PGS001309
(GBE_HC1212)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Other rheumatoid arthritis (time-to-event) rheumatoid arthritis 323
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001309/ScoringFiles/PGS001309.txt.gz
PGS001310
(GBE_HC430)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Rheumatoid arthritis rheumatoid arthritis 175
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001310/ScoringFiles/PGS001310.txt.gz
PGS001311
(GBE_HC1211)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Seropositive rheumatoid arthritis (time-to-event) rheumatoid arthritis 3
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001311/ScoringFiles/PGS001311.txt.gz
PGS001810
(portability-PLR_200.1)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Polycythemia vera acquired polycythemia vera 67
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001810/ScoringFiles/PGS001810.txt.gz
PGS001875
(portability-PLR_714.1)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Rheumatoid arthritis rheumatoid arthritis 256
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001875/ScoringFiles/PGS001875.txt.gz
PGS001876
(portability-PLR_715.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Ankylosing spondylitis ankylosing spondylitis 85
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001876/ScoringFiles/PGS001876.txt.gz
PGS001879
(portability-PLR_727.4)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Ganglion and cyst of synovium, tendon, and bursa ganglion or cyst of synovium/tendon/bursa 210
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001879/ScoringFiles/PGS001879.txt.gz
PGS001882
(portability-PLR_740)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Osteoarthrosis osteoarthritis 11,451
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001882/ScoringFiles/PGS001882.txt.gz
PGS001883
(portability-PLR_743.1)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Osteoporosis osteoporosis 365
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001883/ScoringFiles/PGS001883.txt.gz
PGS002088
(portability-ldpred2_714.1)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Rheumatoid arthritis rheumatoid arthritis 95,083
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002088/ScoringFiles/PGS002088.txt.gz
PGS002089
(portability-ldpred2_715.2)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Ankylosing spondylitis ankylosing spondylitis 22,026
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002089/ScoringFiles/PGS002089.txt.gz
PGS002094
(portability-ldpred2_740)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Osteoarthrosis osteoarthritis 827,887
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002094/ScoringFiles/PGS002094.txt.gz
PGS002095
(portability-ldpred2_743.1)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Osteoporosis osteoporosis 658,775
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002095/ScoringFiles/PGS002095.txt.gz
PGS002260
(PRS_RA)
PGP000286 |
Honda S et al. Arthritis Rheumatol (2022)
Rheumatoid arthritis rheumatoid arthritis 43,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002260/ScoringFiles/PGS002260.txt.gz
PGS002728
(PRS_hip)
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Hip osteoarthritis osteoarthritis, hip 44
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002728/ScoringFiles/PGS002728.txt.gz
PGS002729
(PRS_knee)
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Knee osteoarthritis osteoarthritis, knee 24
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002729/ScoringFiles/PGS002729.txt.gz
PGS002745
(metaPGS_RA)
PGP000357 |
Ishigaki K et al. Nat Genet (2022)
Rheumatoid arthritis rheumatoid arthritis 2,575
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002745/ScoringFiles/PGS002745.txt.gz
PGS002749
(PRS10_TKR)
PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
Total knee replacement total knee arthroplasty,
osteoarthritis, knee
10
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002749/ScoringFiles/PGS002749.txt.gz
PGS002750
(PRS37_THR)
PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
Total hip replacement total hip arthroplasty,
osteoarthritis, hip
37
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002750/ScoringFiles/PGS002750.txt.gz
PGS002763
(Hip_osteoarthritis_prscs)
PGP000364 |
Mars N et al. Am J Hum Genet (2022)
Hip osteoarthritis osteoarthritis, hip 1,052,273
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002763/ScoringFiles/PGS002763.txt.gz
PGS002767
(Knee_osteoarthritis_prscs)
PGP000364 |
Mars N et al. Am J Hum Genet (2022)
Knee osteoarthritis osteoarthritis, knee 1,052,275
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002767/ScoringFiles/PGS002767.txt.gz
PGS002768
(BMD_prscs)
PGP000364 |
Mars N et al. Am J Hum Genet (2022)
Osteoporosis heel bone mineral density,
osteoporosis
1,091,549
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002768/ScoringFiles/PGS002768.txt.gz
PGS002769
(Rheumatoid_arthritis_prscs)
PGP000364 |
Mars N et al. Am J Hum Genet (2022)
Seropositive rheumatoid arthritis rheumatoid arthritis 1,083,565
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002769/ScoringFiles/PGS002769.txt.gz
PGS003420
(PRS100_PRScs)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitis ankylosing spondylitis 100
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003420/ScoringFiles/PGS003420.txt.gz
PGS003421
(PRS16_C+T)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitis ankylosing spondylitis 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003421/ScoringFiles/PGS003421.txt.gz
PGS003422
(PRS16_PRSice2)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitis ankylosing spondylitis 16
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003422/ScoringFiles/PGS003422.txt.gz
PGS003423
(PRS100_Lassosum)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitis ankylosing spondylitis 100
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003423/ScoringFiles/PGS003423.txt.gz
PGS003424
(PRS100_LDpred2)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitis ankylosing spondylitis 100
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003424/ScoringFiles/PGS003424.txt.gz
PGS003994
(dbslmm.auto.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 778,205
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003994/ScoringFiles/PGS003994.txt.gz
PGS004010
(lassosum.auto.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 27,045
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004010/ScoringFiles/PGS004010.txt.gz
PGS004021
(lassosum.CV.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 315,740
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004021/ScoringFiles/PGS004021.txt.gz
PGS004049
(ldpred2.CV.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 373,627
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004049/ScoringFiles/PGS004049.txt.gz
PGS004064
(megaprs.auto.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 402,214
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004064/ScoringFiles/PGS004064.txt.gz
PGS004079
(megaprs.CV.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 402,214
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004079/ScoringFiles/PGS004079.txt.gz
PGS004094
(prscs.auto.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 755,048
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004094/ScoringFiles/PGS004094.txt.gz
PGS004103
(prscs.CV.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 755,048
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004103/ScoringFiles/PGS004103.txt.gz
PGS004118
(pt_clump.auto.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 91
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004118/ScoringFiles/PGS004118.txt.gz
PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 155
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004133/ScoringFiles/PGS004133.txt.gz
PGS004148
(sbayesr.auto.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 671,211
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004148/ScoringFiles/PGS004148.txt.gz
PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Rheumatoid arthritis rheumatoid arthritis 778,275
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004163/ScoringFiles/PGS004163.txt.gz
PGS004255
(GenoBoost_rheumatoid_arthritis_0)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Rheumatoid arthritis rheumatoid arthritis 30
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004255/ScoringFiles/PGS004255.txt.gz
PGS004256
(GenoBoost_rheumatoid_arthritis_1)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Rheumatoid arthritis rheumatoid arthritis 20
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004256/ScoringFiles/PGS004256.txt.gz
PGS004257
(GenoBoost_rheumatoid_arthritis_2)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Rheumatoid arthritis rheumatoid arthritis 20
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004257/ScoringFiles/PGS004257.txt.gz
PGS004258
(GenoBoost_rheumatoid_arthritis_3)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Rheumatoid arthritis rheumatoid arthritis 20
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004258/ScoringFiles/PGS004258.txt.gz
PGS004259
(GenoBoost_rheumatoid_arthritis_4)
PGP000546 |
Ohta R et al. Nat Commun (2024)
Rheumatoid arthritis rheumatoid arthritis 20
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004259/ScoringFiles/PGS004259.txt.gz
PGS004326
(PRS154_RA)
PGP000560 |
Zhang J et al. Environ Health Perspect (2023)
Rheumatoid arthritis rheumatoid arthritis 154
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004326/ScoringFiles/PGS004326.txt.gz
PGS004477
(disease.M13.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M13 (Other arthritis) arthritic joint disease 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004477/ScoringFiles/PGS004477.txt.gz
PGS004478
(disease.M16.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M16 (Coxarthrosis [arthrosis of hip]) osteoarthritis, hip 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004478/ScoringFiles/PGS004478.txt.gz
PGS004479
(disease.M17.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M17 (Gonarthrosis [arthrosis of knee]) osteoarthritis, knee 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004479/ScoringFiles/PGS004479.txt.gz
PGS004480
(disease.M19.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M19 (Other arthrosis) arthropathy 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004480/ScoringFiles/PGS004480.txt.gz
PGS004483
(disease.M25.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M25 (Other joint disorders, not elsewhere classified) arthropathy 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004483/ScoringFiles/PGS004483.txt.gz
PGS004484
(disease.M47.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M47 (Spondylosis) spondylosis 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004484/ScoringFiles/PGS004484.txt.gz
PGS004485
(disease.M48.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M48 (Other spondylopathies) spondylosis 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004485/ScoringFiles/PGS004485.txt.gz
PGS004486
(disease.M51.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M51 (Other intervertebral disk disorders) Intervertebral Disc Displacement 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004486/ScoringFiles/PGS004486.txt.gz
PGS004490
(disease.M81.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M81 (Osteoporosis without pathological fracture) osteoporosis 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004490/ScoringFiles/PGS004490.txt.gz
PGS004495
(disease.osteoporosis.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Osteoporosis osteoporosis 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004495/ScoringFiles/PGS004495.txt.gz
PGS004547
(meta.M13.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M13 (Other arthritis) arthritic joint disease 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004547/ScoringFiles/PGS004547.txt.gz
PGS004548
(meta.M16.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M16 (Coxarthrosis [arthrosis of hip]) osteoarthritis, hip 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004548/ScoringFiles/PGS004548.txt.gz
PGS004549
(meta.M17.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M17 (Gonarthrosis [arthrosis of knee]) osteoarthritis, knee 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004549/ScoringFiles/PGS004549.txt.gz
PGS004550
(meta.M19.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M19 (Other arthrosis) arthropathy 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004550/ScoringFiles/PGS004550.txt.gz
PGS004553
(meta.M25.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M25 (Other joint disorders, not elsewhere classified) arthropathy 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004553/ScoringFiles/PGS004553.txt.gz
PGS004554
(meta.M47.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M47 (Spondylosis) spondylosis 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004554/ScoringFiles/PGS004554.txt.gz
PGS004555
(meta.M48.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M48 (Other spondylopathies) spondylosis 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004555/ScoringFiles/PGS004555.txt.gz
PGS004556
(meta.M51.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M51 (Other intervertebral disk disorders) Intervertebral Disc Displacement 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004556/ScoringFiles/PGS004556.txt.gz
PGS004560
(meta.M81.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
M81 (Osteoporosis without pathological fracture) osteoporosis 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004560/ScoringFiles/PGS004560.txt.gz
PGS004565
(meta.osteoporosis.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Osteoporosis osteoporosis 1,059,939
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004565/ScoringFiles/PGS004565.txt.gz
PGS004809
(osteoporosis_PRSmix_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Osteoporosis osteoporosis 863,731
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004809/ScoringFiles/PGS004809.txt.gz
PGS004810
(osteoporosis_PRSmixPlus_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Osteoporosis osteoporosis 1,876,917
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004810/ScoringFiles/PGS004810.txt.gz
PGS004817
(RA_PRSmix_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Rheumatoid Arthritis rheumatoid arthritis 786,048
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004817/ScoringFiles/PGS004817.txt.gz
PGS004818
(RA_PRSmix_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Rheumatoid Arthritis rheumatoid arthritis 6,580,837
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004818/ScoringFiles/PGS004818.txt.gz
PGS004819
(RA_PRSmixPlus_eur)
PGP000604 |
Truong B et al. Cell Genom (2024)
Rheumatoid Arthritis rheumatoid arthritis 2,624,228
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004819/ScoringFiles/PGS004819.txt.gz
PGS004820
(RA_PRSmixPlus_sas)
PGP000604 |
Truong B et al. Cell Genom (2024)
Rheumatoid Arthritis rheumatoid arthritis 6,580,837
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004820/ScoringFiles/PGS004820.txt.gz
PGS004873
(INTERVENE_MegaPRS_RA)
PGP000618 |
Jermy B et al. Nat Commun (2024)
Rheumatoid arthritis rheumatoid arthritis 551,074
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004873/ScoringFiles/PGS004873.txt.gz
PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
PGP000618 |
Jermy B et al. Nat Commun (2024)
Hip osteoarthritis osteoarthritis, hip 773,587
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004882/ScoringFiles/PGS004882.txt.gz
PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
PGP000618 |
Jermy B et al. Nat Commun (2024)
Knee osteoarthritis osteoarthritis, knee 952,133
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004883/ScoringFiles/PGS004883.txt.gz
PGS005146
(Osteoporosis (PRS-CS; EAS))
PGP000704 |
Jung HU et al. Commun Biol (2025)
Osteoporosis osteoporosis 908,465
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005146/ScoringFiles/PGS005146.txt.gz
PGS005155
(Osteoporosis (PRS-CSx; EAS+EUR))
PGP000704 |
Jung HU et al. Commun Biol (2025)
Osteoporosis osteoporosis 908,465
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005155/ScoringFiles/PGS005155.txt.gz
PGS018416
(PRS_knee)
PGP000833 |
Wei Y et al. Clin Nutr (2024)
Knee osteoarthritis osteoarthritis, knee 83
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018416/ScoringFiles/PGS018416.txt.gz
PGS018417
(PRS_hip)
PGP000833 |
Wei Y et al. Clin Nutr (2024)
Hip osteoarthritis osteoarthritis, hip 70
-
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018417/ScoringFiles/PGS018417.txt.gz
PGS018816
(TPMI_274_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Gout and other crystal arthropathies chondrocalcinosis 2 7,370
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018816/ScoringFiles/PGS018816.txt.gz
PGS018817
(TPMI_274_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Gout and other crystal arthropathies chondrocalcinosis 2 939,841
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018817/ScoringFiles/PGS018817.txt.gz
PGS018818
(TPMI_274_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Gout and other crystal arthropathies chondrocalcinosis 2 483,537
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018818/ScoringFiles/PGS018818.txt.gz
PGS018819
(TPMI_274_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Gout and other crystal arthropathies chondrocalcinosis 2 983,787
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018819/ScoringFiles/PGS018819.txt.gz
PGS018820
(TPMI_274_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Gout and other crystal arthropathies chondrocalcinosis 2 1,071,466
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018820/ScoringFiles/PGS018820.txt.gz
PGS018821
(TPMI_274_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Gout and other crystal arthropathies chondrocalcinosis 2 898,949
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS018821/ScoringFiles/PGS018821.txt.gz
PGS019270
(TPMI_475_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Chronic sinusitis chronic rhinosinusitis 16
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019270/ScoringFiles/PGS019270.txt.gz
PGS019271
(TPMI_475_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Chronic sinusitis chronic rhinosinusitis 939,862
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019271/ScoringFiles/PGS019271.txt.gz
PGS019272
(TPMI_475_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Chronic sinusitis chronic rhinosinusitis 15,628
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019272/ScoringFiles/PGS019272.txt.gz
PGS019273
(TPMI_475_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Chronic sinusitis chronic rhinosinusitis 983,804
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019273/ScoringFiles/PGS019273.txt.gz
PGS019274
(TPMI_475_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Chronic sinusitis chronic rhinosinusitis 968,351
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019274/ScoringFiles/PGS019274.txt.gz
PGS019300
(TPMI_523_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Gingival and periodontal diseases tooth disorder 798,545
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019300/ScoringFiles/PGS019300.txt.gz
PGS019301
(TPMI_523_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Gingival and periodontal diseases tooth disorder 939,885
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019301/ScoringFiles/PGS019301.txt.gz
PGS019302
(TPMI_523_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Gingival and periodontal diseases tooth disorder 25,354
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019302/ScoringFiles/PGS019302.txt.gz
PGS019303
(TPMI_523_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Gingival and periodontal diseases tooth disorder 983,820
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019303/ScoringFiles/PGS019303.txt.gz
PGS019304
(TPMI_523_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Gingival and periodontal diseases tooth disorder 937,449
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019304/ScoringFiles/PGS019304.txt.gz
PGS019305
(TPMI_523.1_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Gingivitis gingivitis 38,420
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019305/ScoringFiles/PGS019305.txt.gz
PGS019306
(TPMI_523.1_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Gingivitis gingivitis 939,855
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019306/ScoringFiles/PGS019306.txt.gz
PGS019307
(TPMI_523.1_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Gingivitis gingivitis 28,584
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019307/ScoringFiles/PGS019307.txt.gz
PGS019308
(TPMI_523.1_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Gingivitis gingivitis 983,793
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019308/ScoringFiles/PGS019308.txt.gz
PGS019309
(TPMI_523.1_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Gingivitis gingivitis 989,009
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019309/ScoringFiles/PGS019309.txt.gz
PGS019310
(TPMI_523.3_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Periodontitis acute or chronic acute pericementitis 800,498
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019310/ScoringFiles/PGS019310.txt.gz
PGS019311
(TPMI_523.3_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Periodontitis acute or chronic acute pericementitis 939,880
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019311/ScoringFiles/PGS019311.txt.gz
PGS019312
(TPMI_523.3_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Periodontitis acute or chronic acute pericementitis 507,697
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019312/ScoringFiles/PGS019312.txt.gz
PGS019313
(TPMI_523.3_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Periodontitis acute or chronic acute pericementitis 983,817
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019313/ScoringFiles/PGS019313.txt.gz
PGS019314
(TPMI_523.3_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Periodontitis acute or chronic acute pericementitis 934,116
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019314/ScoringFiles/PGS019314.txt.gz
PGS019320
(TPMI_526.4_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Temporomandibular joint disorders temporomandibular joint disorder 482,939
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019320/ScoringFiles/PGS019320.txt.gz
PGS019321
(TPMI_526.4_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Temporomandibular joint disorders temporomandibular joint disorder 939,803
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019321/ScoringFiles/PGS019321.txt.gz
PGS019322
(TPMI_526.4_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Temporomandibular joint disorders temporomandibular joint disorder 19,676
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019322/ScoringFiles/PGS019322.txt.gz
PGS019323
(TPMI_526.4_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Temporomandibular joint disorders temporomandibular joint disorder 983,748
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019323/ScoringFiles/PGS019323.txt.gz
PGS019324
(TPMI_526.4_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Temporomandibular joint disorders temporomandibular joint disorder 1,011,614
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019324/ScoringFiles/PGS019324.txt.gz
PGS019623
(TPMI_696.42_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 1,224
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019623/ScoringFiles/PGS019623.txt.gz
PGS019624
(TPMI_696.42_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 939,799
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019624/ScoringFiles/PGS019624.txt.gz
PGS019625
(TPMI_696.42_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 37,037
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019625/ScoringFiles/PGS019625.txt.gz
PGS019626
(TPMI_696.42_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 983,751
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019626/ScoringFiles/PGS019626.txt.gz
PGS019627
(TPMI_696.42_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 1,071,405
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019627/ScoringFiles/PGS019627.txt.gz
PGS019628
(TPMI_696.42_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Psoriatic arthropathy psoriatic arthritis 996,498
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019628/ScoringFiles/PGS019628.txt.gz
PGS019656
(TPMI_714_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 1,304
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019656/ScoringFiles/PGS019656.txt.gz
PGS019657
(TPMI_714_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 939,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019657/ScoringFiles/PGS019657.txt.gz
PGS019658
(TPMI_714_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 28,836
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019658/ScoringFiles/PGS019658.txt.gz
PGS019659
(TPMI_714_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 983,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019659/ScoringFiles/PGS019659.txt.gz
PGS019660
(TPMI_714_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis and other inflammatory polyarthropathies rheumatoid arthritis 554,495
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019660/ScoringFiles/PGS019660.txt.gz
PGS019661
(TPMI_714.1_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 2,493
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019661/ScoringFiles/PGS019661.txt.gz
PGS019662
(TPMI_714.1_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 939,827
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019662/ScoringFiles/PGS019662.txt.gz
PGS019663
(TPMI_714.1_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 33,790
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019663/ScoringFiles/PGS019663.txt.gz
PGS019664
(TPMI_714.1_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 983,784
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019664/ScoringFiles/PGS019664.txt.gz
PGS019665
(TPMI_714.1_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Rheumatoid arthritis rheumatoid arthritis 913,921
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019665/ScoringFiles/PGS019665.txt.gz
PGS019666
(TPMI_715_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 27
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019666/ScoringFiles/PGS019666.txt.gz
PGS019667
(TPMI_715_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 939,889
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019667/ScoringFiles/PGS019667.txt.gz
PGS019668
(TPMI_715_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 294,406
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019668/ScoringFiles/PGS019668.txt.gz
PGS019669
(TPMI_715_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 983,832
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019669/ScoringFiles/PGS019669.txt.gz
PGS019670
(TPMI_715_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Other inflammatory spondylopathies inflammatory spondylopathy 791,011
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019670/ScoringFiles/PGS019670.txt.gz
PGS019671
(TPMI_715.2_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 20
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019671/ScoringFiles/PGS019671.txt.gz
PGS019672
(TPMI_715.2_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 939,888
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019672/ScoringFiles/PGS019672.txt.gz
PGS019673
(TPMI_715.2_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 292,554
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019673/ScoringFiles/PGS019673.txt.gz
PGS019674
(TPMI_715.2_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 983,830
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019674/ScoringFiles/PGS019674.txt.gz
PGS019675
(TPMI_715.2_PRSmix+)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 1,071,343
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019675/ScoringFiles/PGS019675.txt.gz
PGS019676
(TPMI_715.2_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Ankylosing spondylitis ankylosing spondylitis 940,059
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019676/ScoringFiles/PGS019676.txt.gz
PGS019677
(TPMI_716_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 22
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019677/ScoringFiles/PGS019677.txt.gz
PGS019678
(TPMI_716_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 939,889
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019678/ScoringFiles/PGS019678.txt.gz
PGS019679
(TPMI_716_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 11,934
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019679/ScoringFiles/PGS019679.txt.gz
PGS019680
(TPMI_716_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 983,822
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019680/ScoringFiles/PGS019680.txt.gz
PGS019681
(TPMI_716_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Other arthropathies arthropathy 953,818
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019681/ScoringFiles/PGS019681.txt.gz
PGS019682
(TPMI_716.1_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 5
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019682/ScoringFiles/PGS019682.txt.gz
PGS019683
(TPMI_716.1_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 939,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019683/ScoringFiles/PGS019683.txt.gz
PGS019684
(TPMI_716.1_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 483,730
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019684/ScoringFiles/PGS019684.txt.gz
PGS019685
(TPMI_716.1_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 983,781
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019685/ScoringFiles/PGS019685.txt.gz
PGS019686
(TPMI_716.1_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Unspecified polyarthropathy or polyarthritis arthropathy 981,996
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019686/ScoringFiles/PGS019686.txt.gz
PGS019687
(TPMI_716.8_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 40
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019687/ScoringFiles/PGS019687.txt.gz
PGS019688
(TPMI_716.8_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 939,830
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019688/ScoringFiles/PGS019688.txt.gz
PGS019689
(TPMI_716.8_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 402,924
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019689/ScoringFiles/PGS019689.txt.gz
PGS019690
(TPMI_716.8_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 983,781
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019690/ScoringFiles/PGS019690.txt.gz
PGS019691
(TPMI_716.8_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Palindromic rheumatism palindromic rheumatism 1,000,628
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019691/ScoringFiles/PGS019691.txt.gz
PGS019692
(TPMI_716.9_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 19
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019692/ScoringFiles/PGS019692.txt.gz
PGS019693
(TPMI_716.9_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 939,890
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019693/ScoringFiles/PGS019693.txt.gz
PGS019694
(TPMI_716.9_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 485,041
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019694/ScoringFiles/PGS019694.txt.gz
PGS019695
(TPMI_716.9_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 983,823
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019695/ScoringFiles/PGS019695.txt.gz
PGS019696
(TPMI_716.9_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Arthropathy NOS arthropathy 928,818
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019696/ScoringFiles/PGS019696.txt.gz
PGS019722
(TPMI_743_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis osteopenia and pathological fracture osteoporosis,
bone fracture
69,652
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019722/ScoringFiles/PGS019722.txt.gz
PGS019723
(TPMI_743_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis osteopenia and pathological fracture osteoporosis,
bone fracture
365,313
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019723/ScoringFiles/PGS019723.txt.gz
PGS019724
(TPMI_743_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis osteopenia and pathological fracture osteoporosis,
bone fracture
16,942
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019724/ScoringFiles/PGS019724.txt.gz
PGS019725
(TPMI_743_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis osteopenia and pathological fracture osteoporosis,
bone fracture
983,829
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019725/ScoringFiles/PGS019725.txt.gz
PGS019726
(TPMI_743_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis osteopenia and pathological fracture osteoporosis,
bone fracture
957,929
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019726/ScoringFiles/PGS019726.txt.gz
PGS019727
(TPMI_743.11_Lassosum2)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis NOS osteoporosis 419
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019727/ScoringFiles/PGS019727.txt.gz
PGS019728
(TPMI_743.11_LDpred2)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis NOS osteoporosis 317,022
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019728/ScoringFiles/PGS019728.txt.gz
PGS019729
(TPMI_743.11_MegaPRS)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis NOS osteoporosis 27,110
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019729/ScoringFiles/PGS019729.txt.gz
PGS019730
(TPMI_743.11_PRS-CS)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis NOS osteoporosis 983,826
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019730/ScoringFiles/PGS019730.txt.gz
PGS019731
(TPMI_743.11_SBayesR)
PGP000835 |
Chen HH et al. Nature (2025)
Osteoporosis NOS osteoporosis 989,191
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS019731/ScoringFiles/PGS019731.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM)
Evaluated Score PGS Sample Set ID
(PSS)
Performance Source Trait PGS Effect Sizes
(per SD change)
Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000262 PGS000114
(GRS-JIA-20)
PSS000179|
European Ancestry|
3,513 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Juvenile Idiopathic Arthritis OR: 1.838 [1.686, 2.007] AUROC: 0.735 [0.712, 0.758] sex, genetic PCs 1-10
PPM000263 PGS000114
(GRS-JIA-20)
PSS000180|
European Ancestry|
940 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Juvenile Idiopathic Arthritis OR: 2.085 [1.773, 2.471] AUROC: 0.738 [0.705, 0.77] sex, genetic PCs 1-10
PPM000260 PGS000114
(GRS-JIA-20)
PSS000179|
European Ancestry|
3,513 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Juvenile Idiopathic Arthritis OR: 1.831 [1.685, 1.991] AUROC: 0.657 [0.631, 0.683]
PPM000261 PGS000114
(GRS-JIA-20)
PSS000180|
European Ancestry|
940 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Juvenile Idiopathic Arthritis OR: 2.008 [1.731, 2.345] AUROC: 0.671 [0.635, 0.706]
PPM000577 PGS000194
(G-PROB_Rapos)
PSS000315|
European Ancestry|
243 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis AUROC: 0.69 [0.63, 0.76] RAN_Gprob (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit)
PPM000571 PGS000194
(G-PROB_Rapos)
PSS000314|
European Ancestry|
245 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis AUROC: 0.75 [0.68, 0.81] G-PROB_Raneg (Setting II: Assigning patient diagnoses based on medical records)
PPM000565 PGS000194
(G-PROB_Rapos)
PSS000322|
Multi-ancestry (including European)|
1,211 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis AUROC: 0.69 [0.65, 0.72] G-PROB_Raneg (Setting I: Assigning patient diagnoses based on billing codes)
PPM000578 PGS000195
(G-PROB_Raneg)
PSS000315|
European Ancestry|
243 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis AUROC: 0.69 [0.63, 0.76] G-PROB_Rapos (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit)
PPM000572 PGS000195
(G-PROB_Raneg)
PSS000314|
European Ancestry|
245 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis AUROC: 0.75 [0.68, 0.81] G-PROB_Rapos (Setting II: Assigning patient diagnoses based on medical records)
PPM000566 PGS000195
(G-PROB_Raneg)
PSS000322|
Multi-ancestry (including European)|
1,211 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Rheumatoid arhtirits diagnosis in patient with arthritis AUROC: 0.69 [0.65, 0.72] G-PROB_Rapos (Setting I: Assigning patient diagnoses based on billing codes)
PPM000580 PGS000197
(G-PROB_SpA)
PSS000317|
European Ancestry|
243 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Spondyloarthropathy diagnosis in patient with arthritis AUROC: 0.56 [0.33, 0.84] (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit)
PPM000574 PGS000197
(G-PROB_SpA)
PSS000316|
European Ancestry|
245 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Spondyloarthropathy diagnosis in patient with arthritis AUROC: 0.87 [0.76, 0.96] (Setting II: Assigning patient diagnoses based on medical records)
PPM000568 PGS000197
(G-PROB_SpA)
PSS000323|
Multi-ancestry (including European)|
1,211 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Spondyloarthropathy diagnosis in patient with arthritis AUROC: 0.58 [0.5, 0.67] (Setting I: Assigning patient diagnoses based on billing codes)
PPM000581 PGS000198
(G-PROB_PsA)
PSS000313|
European Ancestry|
243 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis AUROC: 0.62 [0.48, 0.8] (Setting III: Selecting patients presenting with inflammatory arthritis at their first visit)
PPM000575 PGS000198
(G-PROB_PsA)
PSS000312|
European Ancestry|
245 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis AUROC: 0.71 [0.63, 0.82] (Setting II: Assigning patient diagnoses based on medical records)
PPM000569 PGS000198
(G-PROB_PsA)
PSS000321|
Multi-ancestry (including European)|
1,211 individuals
PGP000081 |
Knevel R et al. Sci Transl Med (2020)
Reported Trait: Psoriatic arthritis diagnosis in patient with arthritis AUROC: 0.61 [0.52, 0.69] (Setting I: Assigning patient diagnoses based on billing codes)
PPM000874 PGS000324
(GRS-JIA-ERA-20)
PSS000432|
European Ancestry|
594 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Enthesitis-related Arthritis OR: 3.09 [2.07, 5.04] AUROC: 0.93 [0.86, 0.99] sex, genetic PCs 1-10
PPM000873 PGS000324
(GRS-JIA-ERA-20)
PSS000429|
European Ancestry|
3,020 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Enthesitis-related Arthritis OR: 1.86 [1.61, 2.14] AUROC: 0.75 [0.68, 0.82] sex, genetic PCs 1-10
PPM000867 PGS000324
(GRS-JIA-ERA-20)
PSS000429|
European Ancestry|
3,020 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Enthesitis-related Arthritis OR: 1.84 [1.6, 2.17] AUROC: 0.7 [0.63, 0.77]
PPM000868 PGS000324
(GRS-JIA-ERA-20)
PSS000432|
European Ancestry|
594 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Enthesitis-related Arthritis OR: 2.99 [2.11, 4.54] AUROC: 0.84 [0.71, 0.97]
PPM000875 PGS000325
(GRS-JIA-Oli-20)
PSS000430|
European Ancestry|
3,157 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis OR: 1.93 [1.75, 2.13] AUROC: 0.8 [0.77, 0.84] sex, genetic PCs 1-10
PPM000876 PGS000325
(GRS-JIA-Oli-20)
PSS000433|
European Ancestry|
737 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis OR: 2.19 [1.81, 2.71] AUROC: 0.79 [0.76, 0.83] sex, genetic PCs 1-10
PPM000869 PGS000325
(GRS-JIA-Oli-20)
PSS000430|
European Ancestry|
3,157 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis OR: 1.93 [1.76, 2.11] AUROC: 0.77 [0.73, 0.8]
PPM000870 PGS000325
(GRS-JIA-Oli-20)
PSS000433|
European Ancestry|
737 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Oligoarthritis Juvenile Idiophatic Arthritis OR: 2.24 [1.88, 2.71] AUROC: 0.74 [0.7, 0.79]
PPM000878 PGS000326
(GRS-JIA-RFN-20)
PSS000434|
European Ancestry|
653 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Rheumatoid-factor-negative Polyarthritis OR: 1.71 [1.42, 2.07] AUROC: 0.74 [0.68, 0.8] sex, genetic PCs 1-10
PPM000872 PGS000326
(GRS-JIA-RFN-20)
PSS000434|
European Ancestry|
653 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Rheumatoid-factor-negative Polyarthritis OR: 1.69 [1.42, 2.02] AUROC: 0.66 [0.59, 0.73]
PPM000877 PGS000326
(GRS-JIA-RFN-20)
PSS000431|
European Ancestry|
3,089 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Rheumatoid-factor-negative Polyarthritis OR: 1.51 [1.35, 1.68] AUROC: 0.76 [0.72, 0.8] sex, genetic PCs 1-10
PPM000871 PGS000326
(GRS-JIA-RFN-20)
PSS000431|
European Ancestry|
3,089 individuals
PGP000052 |
Cánovas R et al. Ann Rheum Dis (2020)
Reported Trait: Rheumatoid-factor-negative Polyarthritis OR: 1.48 [1.33, 1.64] AUROC: 0.64 [0.59, 0.69]
PPM000971 PGS000342
(wGRS_PsA)
PSS000490|
Ancestry Not Reported|
543 individuals
PGP000111 |
Smith MP et al. J Psoriasis Psoriatic Arthritis (2020)
Reported Trait: Psoriatic arthritis AUROC: 0.562 [0.506, 0.618]
PPM000972 PGS000343
(wGRS_PsA_HLA)
PSS000490|
Ancestry Not Reported|
543 individuals
PGP000111 |
Smith MP et al. J Psoriasis Psoriatic Arthritis (2020)
Reported Trait: Psoriatic arthritis AUROC: 0.569 [0.513, 0.625]
PPM007487 PGS000932
(GBE_HC1248)
PSS004233|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other intervertebral disk disorders AUROC: 0.61914 [0.58359, 0.6547] : 0.02448
Incremental AUROC (full-covars): 0.00264
PGS R2 (no covariates): 0.00207
PGS AUROC (no covariates): 0.53493 [0.49884, 0.57101]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007488 PGS000932
(GBE_HC1248)
PSS004234|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other intervertebral disk disorders AUROC: 0.67311 [0.59003, 0.7562] : 0.04246
Incremental AUROC (full-covars): 0.00165
PGS R2 (no covariates): 0.00022
PGS AUROC (no covariates): 0.51372 [0.42189, 0.60556]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007489 PGS000932
(GBE_HC1248)
PSS004235|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other intervertebral disk disorders AUROC: 0.55895 [0.54143, 0.57647] : 0.00607
Incremental AUROC (full-covars): 0.01294
PGS R2 (no covariates): 0.00286
PGS AUROC (no covariates): 0.54031 [0.52281, 0.55781]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007490 PGS000932
(GBE_HC1248)
PSS004236|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other intervertebral disk disorders AUROC: 0.59693 [0.5672, 0.62666] : 0.01653
Incremental AUROC (full-covars): 0.00562
PGS R2 (no covariates): 0.00176
PGS AUROC (no covariates): 0.52887 [0.49726, 0.56049]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007491 PGS000932
(GBE_HC1248)
PSS004237|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other intervertebral disk disorders AUROC: 0.54155 [0.53124, 0.55187] : 0.00313
Incremental AUROC (full-covars): 0.01449
PGS R2 (no covariates): 0.00232
PGS AUROC (no covariates): 0.5375 [0.52711, 0.54788]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007644 PGS000964
(GBE_HC176)
PSS004326|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Prolapsed disc/slipped disc AUROC: 0.63682 [0.56928, 0.70437] : 0.02156
Incremental AUROC (full-covars): 0.00372
PGS R2 (no covariates): 0.00327
PGS AUROC (no covariates): 0.55166 [0.47346, 0.62985]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007645 PGS000964
(GBE_HC176)
PSS004327|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Prolapsed disc/slipped disc AUROC: 0.81007 [0.70133, 0.91881] : 0.11316
Incremental AUROC (full-covars): -0.00081
PGS R2 (no covariates): 0.00529
PGS AUROC (no covariates): 0.44295 [0.26666, 0.61923]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007646 PGS000964
(GBE_HC176)
PSS004328|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Prolapsed disc/slipped disc AUROC: 0.56388 [0.53738, 0.59039] : 0.00535
Incremental AUROC (full-covars): 0.00616
PGS R2 (no covariates): 0.00079
PGS AUROC (no covariates): 0.5207 [0.49331, 0.54808]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007647 PGS000964
(GBE_HC176)
PSS004329|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Prolapsed disc/slipped disc AUROC: 0.61724 [0.56387, 0.67062] : 0.01708
Incremental AUROC (full-covars): 0.00757
PGS R2 (no covariates): 0.00213
PGS AUROC (no covariates): 0.54913 [0.49663, 0.60163]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007648 PGS000964
(GBE_HC176)
PSS004330|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Prolapsed disc/slipped disc AUROC: 0.5452 [0.52946, 0.56094] : 0.0026
Incremental AUROC (full-covars): 0.01313
PGS R2 (no covariates): 0.00226
PGS AUROC (no covariates): 0.54225 [0.5262, 0.5583]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007658 PGS000967
(GBE_HC1221)
PSS004208|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE coxarthrosis [arthrosis of hip] AUROC: 0.63448 [0.57611, 0.69284] : 0.02258
Incremental AUROC (full-covars): 0.01789
PGS R2 (no covariates): 0.0065
PGS AUROC (no covariates): 0.57452 [0.51022, 0.63883]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007659 PGS000967
(GBE_HC1221)
PSS004209|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE coxarthrosis [arthrosis of hip] AUROC: 0.67991 [0.52221, 0.83761] : 0.03974
Incremental AUROC (full-covars): 0.00141
PGS R2 (no covariates): 0.00044
PGS AUROC (no covariates): 0.52299 [0.39821, 0.64778]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007660 PGS000967
(GBE_HC1221)
PSS004210|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE coxarthrosis [arthrosis of hip] AUROC: 0.71352 [0.69682, 0.73022] : 0.07227
Incremental AUROC (full-covars): 0.00368
PGS R2 (no covariates): 0.00258
PGS AUROC (no covariates): 0.54164 [0.52116, 0.56213]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007661 PGS000967
(GBE_HC1221)
PSS004211|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE coxarthrosis [arthrosis of hip] AUROC: 0.72467 [0.66733, 0.78201] : 0.06598
Incremental AUROC (full-covars): -0.00237
PGS R2 (no covariates): 1e-05
PGS AUROC (no covariates): 0.50363 [0.44232, 0.56493]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM007662 PGS000967
(GBE_HC1221)
PSS004212|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE coxarthrosis [arthrosis of hip] AUROC: 0.69051 [0.68108, 0.69995] : 0.06247
Incremental AUROC (full-covars): 0.00918
PGS R2 (no covariates): 0.00628
PGS AUROC (no covariates): 0.5611 [0.55051, 0.57168]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008289 PGS001110
(GBE_HC1209)
PSS004183|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE reactive arthropathies AUROC: 0.9594 [0.92062, 0.99818] : 0.17918
Incremental AUROC (full-covars): 0.00395
PGS R2 (no covariates): 0.00991
PGS AUROC (no covariates): 0.72061 [0.49213, 0.9491]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008290 PGS001110
(GBE_HC1209)
PSS004185|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE reactive arthropathies AUROC: 0.77096 [0.63921, 0.90271] : 0.09743
Incremental AUROC (full-covars): 0.03274
PGS R2 (no covariates): 0.03411
PGS AUROC (no covariates): 0.65137 [0.47674, 0.826]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008291 PGS001110
(GBE_HC1209)
PSS004186|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE reactive arthropathies AUROC: 0.94552 [0.83969, 1.0] : 0.25627
Incremental AUROC (full-covars): 0.00045
PGS R2 (no covariates): 0.00071
PGS AUROC (no covariates): 0.67786 [0.66768, 0.68805]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008292 PGS001110
(GBE_HC1209)
PSS004187|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE reactive arthropathies AUROC: 0.6839 [0.58647, 0.78132] : 0.03053
Incremental AUROC (full-covars): 0.07922
PGS R2 (no covariates): 0.02879
PGS AUROC (no covariates): 0.66167 [0.54859, 0.77475]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008403 PGS001135
(GBE_HC78)
PSS004627|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Arthritis (nos) AUROC: 0.7166 [0.69191, 0.7413] : 0.0961
Incremental AUROC (full-covars): -0.00204
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.50267 [0.47421, 0.53114]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008404 PGS001135
(GBE_HC78)
PSS004628|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Arthritis (nos) AUROC: 0.78855 [0.73521, 0.8419] : 0.13042
Incremental AUROC (full-covars): -0.00593
PGS R2 (no covariates): 0.00821
PGS AUROC (no covariates): 0.42483 [0.32454, 0.52511]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008405 PGS001135
(GBE_HC78)
PSS004629|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Arthritis (nos) AUROC: 0.67424 [0.65969, 0.68878] : 0.05468
Incremental AUROC (full-covars): 0.00314
PGS R2 (no covariates): 0.00291
PGS AUROC (no covariates): 0.53928 [0.52302, 0.55554]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008406 PGS001135
(GBE_HC78)
PSS004630|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Arthritis (nos) AUROC: 0.71014 [0.68888, 0.73139] : 0.08893
Incremental AUROC (full-covars): 0.00207
PGS R2 (no covariates): 0.00153
PGS AUROC (no covariates): 0.52639 [0.5015, 0.55128]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008407 PGS001135
(GBE_HC78)
PSS004631|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Arthritis (nos) AUROC: 0.64961 [0.64135, 0.65786] : 0.04342
Incremental AUROC (full-covars): 0.00228
PGS R2 (no covariates): 0.00147
PGS AUROC (no covariates): 0.52671 [0.51771, 0.53571]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008609 PGS001192
(GBE_HC1222)
PSS004213|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE gonarthrosis [arthrosis of knee] AUROC: 0.68497 [0.65949, 0.71044] : 0.07256
Incremental AUROC (full-covars): -0.01106
PGS R2 (no covariates): 0.00014
PGS AUROC (no covariates): 0.48548 [0.45782, 0.51313]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008610 PGS001192
(GBE_HC1222)
PSS004214|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE gonarthrosis [arthrosis of knee] AUROC: 0.6973 [0.62907, 0.76552] : 0.05404
Incremental AUROC (full-covars): -0.01876
PGS R2 (no covariates): 0.00104
PGS AUROC (no covariates): 0.48101 [0.40847, 0.55354]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008611 PGS001192
(GBE_HC1222)
PSS004215|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE gonarthrosis [arthrosis of knee] AUROC: 0.66024 [0.6461, 0.67438] PGS R2 (no covariates): 0.00516
: 0.04745
Incremental AUROC (full-covars): 0.00488
PGS AUROC (no covariates): 0.54777 [0.53172, 0.56382]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008612 PGS001192
(GBE_HC1222)
PSS004216|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE gonarthrosis [arthrosis of knee] AUROC: 0.72749 [0.70853, 0.74646] : 0.11678
Incremental AUROC (full-covars): 0.00024
PGS R2 (no covariates): 0.00229
PGS AUROC (no covariates): 0.53307 [0.5103, 0.55585]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008613 PGS001192
(GBE_HC1222)
PSS004217|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE gonarthrosis [arthrosis of knee] AUROC: 0.64504 [0.63733, 0.65274] : 0.04312
Incremental AUROC (full-covars): 0.0104
PGS R2 (no covariates): 0.0068
PGS AUROC (no covariates): 0.55655 [0.54824, 0.56485]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008840 PGS001267
(GBE_HC422)
PSS004486|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.86744 [0.75569, 0.97918] : 0.1463
Incremental AUROC (full-covars): -0.00062
PGS R2 (no covariates): 0.00216
PGS AUROC (no covariates): 0.4722 [0.12421, 0.82018]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008841 PGS001267
(GBE_HC422)
PSS004487|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.98913 [0.972, 1.0] : 0.44316
Incremental AUROC (full-covars): 0.0423
PGS R2 (no covariates): 0.24382
PGS AUROC (no covariates): 0.81698 [0.46329, 1.0]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008842 PGS001267
(GBE_HC422)
PSS004488|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.73638 [0.67151, 0.80124] : 0.10414
Incremental AUROC (full-covars): 0.06004
PGS R2 (no covariates): 0.07222
PGS AUROC (no covariates): 0.67545 [0.60736, 0.74353]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008843 PGS001267
(GBE_HC422)
PSS004489|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.73535 [0.61203, 0.85867] : 0.03713
Incremental AUROC (full-covars): -0.01782
PGS R2 (no covariates): 0.00902
PGS AUROC (no covariates): 0.42181 [0.29024, 0.55338]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008844 PGS001267
(GBE_HC422)
PSS004490|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.74328 [0.70673, 0.77983] : 0.10925
Incremental AUROC (full-covars): 0.12994
PGS R2 (no covariates): 0.09877
PGS AUROC (no covariates): 0.72651 [0.68965, 0.76337]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008845 PGS001268
(GBE_HC1242)
PSS004228|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE ankylosing spondylitis AUROC: 0.86811 [0.75774, 0.97849] : 0.14598
Incremental AUROC (full-covars): 6e-05
PGS R2 (no covariates): 0.00104
PGS AUROC (no covariates): 0.48424 [0.12443, 0.84406]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008846 PGS001268
(GBE_HC1242)
PSS004229|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE ankylosing spondylitis AUROC: 0.99148 [0.9789, 1.0] : 0.44858
Incremental AUROC (full-covars): 0.04465
PGS R2 (no covariates): 0.23755
PGS AUROC (no covariates): 0.81257 [0.45025, 1.0]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008847 PGS001268
(GBE_HC1242)
PSS004230|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE ankylosing spondylitis AUROC: 0.73336 [0.66901, 0.79772] : 0.10217
Incremental AUROC (full-covars): 0.0575
PGS R2 (no covariates): 0.06991
PGS AUROC (no covariates): 0.67405 [0.607, 0.74111]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008848 PGS001268
(GBE_HC1242)
PSS004231|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE ankylosing spondylitis AUROC: 0.73282 [0.61573, 0.84991] : 0.03979
Incremental AUROC (full-covars): -0.01963
PGS R2 (no covariates): 0.00774
PGS AUROC (no covariates): 0.4297 [0.29438, 0.56502]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008849 PGS001268
(GBE_HC1242)
PSS004232|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE ankylosing spondylitis AUROC: 0.74878 [0.71314, 0.78442] : 0.115
Incremental AUROC (full-covars): 0.12686
PGS R2 (no covariates): 0.10232
PGS AUROC (no covariates): 0.7346 [0.69884, 0.77037]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008863 PGS001273
(GBE_HC22)
PSS004369|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoporosis AUROC: 0.75545 [0.70356, 0.80735] : 0.08703
Incremental AUROC (full-covars): -0.00106
PGS R2 (no covariates): 0.00045
PGS AUROC (no covariates): 0.51891 [0.45926, 0.57855]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008864 PGS001273
(GBE_HC22)
PSS004370|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoporosis AUROC: 0.85769 [0.79768, 0.9177] : 0.20187
Incremental AUROC (full-covars): -0.00208
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.50947 [0.39122, 0.62773]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008865 PGS001273
(GBE_HC22)
PSS004371|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoporosis AUROC: 0.78972 [0.77584, 0.8036] : 0.14567
Incremental AUROC (full-covars): 0.00477
PGS R2 (no covariates): 0.00688
PGS AUROC (no covariates): 0.5685 [0.55009, 0.58691]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008866 PGS001273
(GBE_HC22)
PSS004372|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoporosis AUROC: 0.82202 [0.79395, 0.85009] : 0.17031
Incremental AUROC (full-covars): 0.00037
PGS R2 (no covariates): 5e-05
PGS AUROC (no covariates): 0.50461 [0.4652, 0.54402]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008867 PGS001273
(GBE_HC22)
PSS004373|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoporosis AUROC: 0.7643 [0.75478, 0.77381] : 0.1146
Incremental AUROC (full-covars): 0.00589
PGS R2 (no covariates): 0.00698
PGS AUROC (no covariates): 0.5684 [0.55603, 0.58076]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008868 PGS001274
(GBE_HC1268)
PSS004243|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE osteoporosis without pathological fracture AUROC: 0.74925 [0.69511, 0.80339] : 0.08288
Incremental AUROC (full-covars): -0.00137
PGS R2 (no covariates): 0.00122
PGS AUROC (no covariates): 0.51972 [0.45381, 0.58563]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008869 PGS001274
(GBE_HC1268)
PSS004244|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE osteoporosis without pathological fracture AUROC: 0.81083 [0.73828, 0.88338] : 0.14813
Incremental AUROC (full-covars): -0.0044
PGS R2 (no covariates): 9e-05
PGS AUROC (no covariates): 0.50546 [0.40063, 0.61028]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008870 PGS001274
(GBE_HC1268)
PSS004245|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE osteoporosis without pathological fracture AUROC: 0.79652 [0.78363, 0.8094] : 0.15697
Incremental AUROC (full-covars): 0.00777
PGS R2 (no covariates): 0.00945
PGS AUROC (no covariates): 0.57595 [0.55816, 0.59374]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008871 PGS001274
(GBE_HC1268)
PSS004246|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE osteoporosis without pathological fracture AUROC: 0.81463 [0.78571, 0.84355] : 0.16403
Incremental AUROC (full-covars): -0.00198
PGS R2 (no covariates): 0.00037
PGS AUROC (no covariates): 0.51416 [0.47459, 0.55374]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008872 PGS001274
(GBE_HC1268)
PSS004247|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE osteoporosis without pathological fracture AUROC: 0.77492 [0.76604, 0.7838] : 0.12779
Incremental AUROC (full-covars): 0.00797
PGS R2 (no covariates): 0.0089
PGS AUROC (no covariates): 0.57419 [0.56237, 0.586]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008933 PGS001287
(GBE_HC91)
PSS004706|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriatic arthropathy AUROC: 0.98006 [0.94602, 1.0] Incremental AUROC (full-covars): 0.00516
: 0.29301
PGS R2 (no covariates): 0.01017
PGS AUROC (no covariates): 0.72132 [0.63231, 0.81034]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008934 PGS001287
(GBE_HC91)
PSS004707|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriatic arthropathy AUROC: 0.99354 [0.98059, 1.0] : 0.5357
Incremental AUROC (full-covars): -0.00088
PGS R2 (no covariates): 0.00227
PGS AUROC (no covariates): 0.47826 [0.0, 0.96911]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008935 PGS001287
(GBE_HC91)
PSS004708|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriatic arthropathy AUROC: 0.72814 [0.67154, 0.78475] : 0.05154
Incremental AUROC (full-covars): 0.08346
PGS R2 (no covariates): 0.0335
PGS AUROC (no covariates): 0.67648 [0.61155, 0.7414]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008936 PGS001287
(GBE_HC91)
PSS004709|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriatic arthropathy AUROC: 0.71827 [0.61363, 0.82292] : 0.04395
Incremental AUROC (full-covars): 0.00838
PGS R2 (no covariates): 0.00229
PGS AUROC (no covariates): 0.56943 [0.44876, 0.69011]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008937 PGS001287
(GBE_HC91)
PSS004710|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Psoriatic arthropathy AUROC: 0.6376 [0.60073, 0.67447] : 0.02161
Incremental AUROC (full-covars): 0.0945
PGS R2 (no covariates): 0.02111
PGS AUROC (no covariates): 0.63567 [0.598, 0.67334]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008948 PGS001290
(GBE_HC376)
PSS004461|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoarthritis AUROC: 0.75416 [0.72668, 0.78163] : 0.12216
Incremental AUROC (full-covars): -3e-05
PGS R2 (no covariates): 0.00052
PGS AUROC (no covariates): 0.51951 [0.48655, 0.55248]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008949 PGS001290
(GBE_HC376)
PSS004462|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoarthritis AUROC: 0.74181 [0.68024, 0.80338] : 0.09715
Incremental AUROC (full-covars): -0.00139
PGS R2 (no covariates): 0.00189
PGS AUROC (no covariates): 0.54245 [0.47153, 0.61338]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008950 PGS001290
(GBE_HC376)
PSS004463|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoarthritis AUROC: 0.70244 [0.69044, 0.71444] : 0.08191
Incremental AUROC (full-covars): 0.0007
PGS R2 (no covariates): 0.0006
PGS AUROC (no covariates): 0.51661 [0.5024, 0.53082]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008951 PGS001290
(GBE_HC376)
PSS004464|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoarthritis AUROC: 0.72534 [0.70181, 0.74887] : 0.09768
Incremental AUROC (full-covars): -0.00173
PGS R2 (no covariates): 1e-05
PGS AUROC (no covariates): 0.49787 [0.47035, 0.52539]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM008952 PGS001290
(GBE_HC376)
PSS004465|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Osteoarthritis AUROC: 0.67419 [0.66753, 0.68085] : 0.0674
Incremental AUROC (full-covars): 0.00134
PGS R2 (no covariates): 0.00109
PGS AUROC (no covariates): 0.52166 [0.51404, 0.52927]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009039 PGS001309
(GBE_HC1212)
PSS004193|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other rheumatoid arthritis AUROC: 0.69751 [0.65515, 0.73988] : 0.05129
Incremental AUROC (full-covars): -0.00017
PGS R2 (no covariates): 0.00056
PGS AUROC (no covariates): 0.52591 [0.47486, 0.57696]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009040 PGS001309
(GBE_HC1212)
PSS004194|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other rheumatoid arthritis AUROC: 0.67331 [0.56418, 0.78244] : 0.07058
Incremental AUROC (full-covars): -0.02511
PGS R2 (no covariates): 0.0
PGS AUROC (no covariates): 0.50714 [0.3797, 0.63457]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009041 PGS001309
(GBE_HC1212)
PSS004195|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other rheumatoid arthritis AUROC: 0.6872 [0.66167, 0.71273] : 0.04826
Incremental AUROC (full-covars): 0.02601
PGS R2 (no covariates): 0.01537
PGS AUROC (no covariates): 0.59782 [0.56885, 0.62679]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009042 PGS001309
(GBE_HC1212)
PSS004196|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other rheumatoid arthritis AUROC: 0.70239 [0.66722, 0.73755] : 0.06164
Incremental AUROC (full-covars): -0.00362
PGS R2 (no covariates): 0.00158
PGS AUROC (no covariates): 0.53481 [0.4923, 0.57731]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009043 PGS001309
(GBE_HC1212)
PSS004197|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE other rheumatoid arthritis AUROC: 0.66538 [0.65101, 0.67976] : 0.03893
Incremental AUROC (full-covars): 0.03207
PGS R2 (no covariates): 0.01495
PGS AUROC (no covariates): 0.59784 [0.582, 0.61368]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009044 PGS001310
(GBE_HC430)
PSS004491|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Rheumatoid arthritis AUROC: 0.70522 [0.66309, 0.74736] : 0.0544
Incremental AUROC (full-covars): 0.00203
PGS R2 (no covariates): 0.00109
PGS AUROC (no covariates): 0.53147 [0.47999, 0.58294]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009045 PGS001310
(GBE_HC430)
PSS004492|
East Asian Ancestry|
1,704 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Rheumatoid arthritis AUROC: 0.66116 [0.54578, 0.77655] : 0.06929
Incremental AUROC (full-covars): -0.02514
PGS R2 (no covariates): 0.00033
PGS AUROC (no covariates): 0.52178 [0.38366, 0.6599]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009046 PGS001310
(GBE_HC430)
PSS004493|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Rheumatoid arthritis AUROC: 0.68857 [0.6632, 0.71393] : 0.04919
Incremental AUROC (full-covars): 0.02092
PGS R2 (no covariates): 0.01316
PGS AUROC (no covariates): 0.58714 [0.55751, 0.61676]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009047 PGS001310
(GBE_HC430)
PSS004494|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Rheumatoid arthritis AUROC: 0.70402 [0.66905, 0.73899] : 0.06207
Incremental AUROC (full-covars): -0.0019
PGS R2 (no covariates): 0.00142
PGS AUROC (no covariates): 0.53137 [0.48984, 0.57291]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009048 PGS001310
(GBE_HC430)
PSS004495|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Rheumatoid arthritis AUROC: 0.66508 [0.65049, 0.67967] : 0.03894
Incremental AUROC (full-covars): 0.03077
PGS R2 (no covariates): 0.01509
PGS AUROC (no covariates): 0.60018 [0.58428, 0.61607]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009049 PGS001311
(GBE_HC1211)
PSS004188|
African Ancestry|
6,497 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE seropositive rheumatoid arthritis AUROC: 0.90345 [0.82233, 0.98457] : 0.16794
Incremental AUROC (full-covars): -0.00669
PGS R2 (no covariates): 0.01613
PGS AUROC (no covariates): 0.39273 [0.11505, 0.67041]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009050 PGS001311
(GBE_HC1211)
PSS004190|
European Ancestry|
24,905 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE seropositive rheumatoid arthritis AUROC: 0.76787 [0.6839, 0.85184] : 0.08412
Incremental AUROC (full-covars): 0.0418
PGS R2 (no covariates): 0.05847
PGS AUROC (no covariates): 0.73164 [0.63667, 0.82662]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009051 PGS001311
(GBE_HC1211)
PSS004191|
South Asian Ancestry|
7,831 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE seropositive rheumatoid arthritis AUROC: 0.76865 [0.6608, 0.87651] : 0.08089
Incremental AUROC (full-covars): -0.00731
PGS R2 (no covariates): 0.00567
PGS AUROC (no covariates): 0.50626 [0.35145, 0.66107]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009052 PGS001311
(GBE_HC1211)
PSS004192|
European Ancestry|
67,425 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: TTE seropositive rheumatoid arthritis AUROC: 0.73785 [0.69634, 0.77936] : 0.05309
Incremental AUROC (full-covars): 0.09202
PGS R2 (no covariates): 0.04612
PGS AUROC (no covariates): 0.7072 [0.65945, 0.75495]
age, sex, UKB array type, Genotype PCs Full Model & PGS R2 is estimated using Nagelkerke's method
PPM009382 PGS001810
(portability-PLR_200.1)
PSS009280|
European Ancestry|
19,539 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Polycythemia vera Partial Correlation (partial-r): 0.017 [0.003, 0.031] sex, age, birth date, deprivation index, 16 PCs
PPM009383 PGS001810
(portability-PLR_200.1)
PSS009054|
European Ancestry|
4,052 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Polycythemia vera Partial Correlation (partial-r): 0.0195 [-0.0114, 0.0503] sex, age, birth date, deprivation index, 16 PCs
PPM009384 PGS001810
(portability-PLR_200.1)
PSS008608|
European Ancestry|
6,489 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Polycythemia vera Partial Correlation (partial-r): 0.026 [0.0016, 0.0503] sex, age, birth date, deprivation index, 16 PCs
PPM009385 PGS001810
(portability-PLR_200.1)
PSS008384|
Greater Middle Eastern Ancestry|
1,178 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Polycythemia vera Partial Correlation (partial-r): -0.0173 [-0.0748, 0.0404] sex, age, birth date, deprivation index, 16 PCs
PPM009386 PGS001810
(portability-PLR_200.1)
PSS008162|
South Asian Ancestry|
6,171 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Polycythemia vera Partial Correlation (partial-r): -0.0038 [-0.0288, 0.0212] sex, age, birth date, deprivation index, 16 PCs
PPM009387 PGS001810
(portability-PLR_200.1)
PSS007949|
East Asian Ancestry|
1,787 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Polycythemia vera Partial Correlation (partial-r): -0.0072 [-0.0538, 0.0395] sex, age, birth date, deprivation index, 16 PCs
PPM009888 PGS001875
(portability-PLR_714.1)
PSS009352|
European Ancestry|
18,393 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0416 [0.0272, 0.056] sex, age, birth date, deprivation index, 16 PCs
PPM009889 PGS001875
(portability-PLR_714.1)
PSS009126|
European Ancestry|
3,878 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0554 [0.0239, 0.0868] sex, age, birth date, deprivation index, 16 PCs
PPM009890 PGS001875
(portability-PLR_714.1)
PSS008680|
European Ancestry|
6,241 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0322 [0.0073, 0.057] sex, age, birth date, deprivation index, 16 PCs
PPM009891 PGS001875
(portability-PLR_714.1)
PSS008454|
Greater Middle Eastern Ancestry|
1,128 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0363 [-0.0226, 0.095] sex, age, birth date, deprivation index, 16 PCs
PPM009892 PGS001875
(portability-PLR_714.1)
PSS008234|
South Asian Ancestry|
5,728 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0097 [-0.0163, 0.0356] sex, age, birth date, deprivation index, 16 PCs
PPM009893 PGS001875
(portability-PLR_714.1)
PSS008014|
East Asian Ancestry|
1,754 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0277 [-0.0194, 0.0746] sex, age, birth date, deprivation index, 16 PCs
PPM009894 PGS001875
(portability-PLR_714.1)
PSS007799|
African Ancestry|
2,277 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): -0.0138 [-0.055, 0.0275] sex, age, birth date, deprivation index, 16 PCs
PPM009895 PGS001875
(portability-PLR_714.1)
PSS008903|
African Ancestry|
3,634 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): -0.0251 [-0.0577, 0.0075] sex, age, birth date, deprivation index, 16 PCs
PPM009896 PGS001876
(portability-PLR_715.2)
PSS009353|
European Ancestry|
18,262 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.0797 [0.0653, 0.0941] sex, age, birth date, deprivation index, 16 PCs
PPM009897 PGS001876
(portability-PLR_715.2)
PSS009127|
European Ancestry|
3,854 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.0453 [0.0137, 0.0769] sex, age, birth date, deprivation index, 16 PCs
PPM009898 PGS001876
(portability-PLR_715.2)
PSS008681|
European Ancestry|
6,216 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.0521 [0.0272, 0.0769] sex, age, birth date, deprivation index, 16 PCs
PPM009899 PGS001876
(portability-PLR_715.2)
PSS008455|
Greater Middle Eastern Ancestry|
1,124 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.1472 [0.0889, 0.2044] sex, age, birth date, deprivation index, 16 PCs
PPM009900 PGS001876
(portability-PLR_715.2)
PSS008235|
South Asian Ancestry|
5,671 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.0279 [0.0019, 0.054] sex, age, birth date, deprivation index, 16 PCs
PPM009917 PGS001879
(portability-PLR_727.4)
PSS009356|
European Ancestry|
18,953 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ganglion and cyst of synovium, tendon, and bursa Partial Correlation (partial-r): 0.0188 [0.0046, 0.033] sex, age, birth date, deprivation index, 16 PCs
PPM009918 PGS001879
(portability-PLR_727.4)
PSS009130|
European Ancestry|
3,909 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ganglion and cyst of synovium, tendon, and bursa Partial Correlation (partial-r): -0.0022 [-0.0337, 0.0292] sex, age, birth date, deprivation index, 16 PCs
PPM009919 PGS001879
(portability-PLR_727.4)
PSS008684|
European Ancestry|
6,366 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ganglion and cyst of synovium, tendon, and bursa Partial Correlation (partial-r): -0.0003 [-0.0249, 0.0243] sex, age, birth date, deprivation index, 16 PCs
PPM009920 PGS001879
(portability-PLR_727.4)
PSS008458|
Greater Middle Eastern Ancestry|
1,137 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ganglion and cyst of synovium, tendon, and bursa Partial Correlation (partial-r): -0.0036 [-0.0623, 0.0551] sex, age, birth date, deprivation index, 16 PCs
PPM009921 PGS001879
(portability-PLR_727.4)
PSS008238|
South Asian Ancestry|
5,964 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ganglion and cyst of synovium, tendon, and bursa Partial Correlation (partial-r): 0.0056 [-0.0198, 0.031] sex, age, birth date, deprivation index, 16 PCs
PPM009922 PGS001879
(portability-PLR_727.4)
PSS008017|
East Asian Ancestry|
1,759 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ganglion and cyst of synovium, tendon, and bursa Partial Correlation (partial-r): -0.0128 [-0.0598, 0.0342] sex, age, birth date, deprivation index, 16 PCs
PPM009923 PGS001879
(portability-PLR_727.4)
PSS007802|
African Ancestry|
2,358 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ganglion and cyst of synovium, tendon, and bursa Partial Correlation (partial-r): -0.0261 [-0.0666, 0.0144] sex, age, birth date, deprivation index, 16 PCs
PPM009924 PGS001879
(portability-PLR_727.4)
PSS008906|
African Ancestry|
3,779 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ganglion and cyst of synovium, tendon, and bursa Partial Correlation (partial-r): 0.0184 [-0.0135, 0.0504] sex, age, birth date, deprivation index, 16 PCs
PPM009940 PGS001882
(portability-PLR_740)
PSS009359|
European Ancestry|
20,000 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0409 [0.027, 0.0547] sex, age, birth date, deprivation index, 16 PCs
PPM009941 PGS001882
(portability-PLR_740)
PSS009133|
European Ancestry|
4,136 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0415 [0.0109, 0.0719] sex, age, birth date, deprivation index, 16 PCs
PPM009942 PGS001882
(portability-PLR_740)
PSS008687|
European Ancestry|
6,660 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0357 [0.0117, 0.0597] sex, age, birth date, deprivation index, 16 PCs
PPM009943 PGS001882
(portability-PLR_740)
PSS008461|
Greater Middle Eastern Ancestry|
1,200 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0326 [-0.0246, 0.0895] sex, age, birth date, deprivation index, 16 PCs
PPM009944 PGS001882
(portability-PLR_740)
PSS008241|
South Asian Ancestry|
6,331 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0211 [-0.0036, 0.0457] sex, age, birth date, deprivation index, 16 PCs
PPM009945 PGS001882
(portability-PLR_740)
PSS008019|
East Asian Ancestry|
1,810 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0051 [-0.0412, 0.0514] sex, age, birth date, deprivation index, 16 PCs
PPM009946 PGS001882
(portability-PLR_740)
PSS007805|
African Ancestry|
2,484 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0312 [-0.0083, 0.0706] sex, age, birth date, deprivation index, 16 PCs
PPM009947 PGS001882
(portability-PLR_740)
PSS008909|
African Ancestry|
3,924 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0103 [-0.0211, 0.0417] sex, age, birth date, deprivation index, 16 PCs
PPM009948 PGS001883
(portability-PLR_743.1)
PSS009360|
European Ancestry|
19,982 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0308 [0.017, 0.0447] sex, age, birth date, deprivation index, 16 PCs
PPM009949 PGS001883
(portability-PLR_743.1)
PSS009134|
European Ancestry|
4,130 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): -0.0002 [-0.0308, 0.0303] sex, age, birth date, deprivation index, 16 PCs
PPM009950 PGS001883
(portability-PLR_743.1)
PSS008688|
European Ancestry|
6,657 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0348 [0.0108, 0.0588] sex, age, birth date, deprivation index, 16 PCs
PPM009952 PGS001883
(portability-PLR_743.1)
PSS008242|
South Asian Ancestry|
6,327 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): -0.0028 [-0.0274, 0.0219] sex, age, birth date, deprivation index, 16 PCs
PPM009953 PGS001883
(portability-PLR_743.1)
PSS008020|
East Asian Ancestry|
1,808 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0046 [-0.0418, 0.0509] sex, age, birth date, deprivation index, 16 PCs
PPM009954 PGS001883
(portability-PLR_743.1)
PSS007806|
African Ancestry|
2,483 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): -0.0024 [-0.0419, 0.0371] sex, age, birth date, deprivation index, 16 PCs
PPM009955 PGS001883
(portability-PLR_743.1)
PSS008910|
African Ancestry|
3,923 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0028 [-0.0286, 0.0342] sex, age, birth date, deprivation index, 16 PCs
PPM009951 PGS001883
(portability-PLR_743.1)
PSS008462|
Greater Middle Eastern Ancestry|
1,199 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0115 [-0.0456, 0.0686] sex, age, birth date, deprivation index, 16 PCs
PPM011564 PGS002088
(portability-ldpred2_714.1)
PSS009352|
European Ancestry|
18,393 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0434 [0.029, 0.0578] sex, age, birth date, deprivation index, 16 PCs
PPM011565 PGS002088
(portability-ldpred2_714.1)
PSS009126|
European Ancestry|
3,878 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0532 [0.0217, 0.0846] sex, age, birth date, deprivation index, 16 PCs
PPM011566 PGS002088
(portability-ldpred2_714.1)
PSS008680|
European Ancestry|
6,241 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0284 [0.0036, 0.0532] sex, age, birth date, deprivation index, 16 PCs
PPM011568 PGS002088
(portability-ldpred2_714.1)
PSS008234|
South Asian Ancestry|
5,728 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0135 [-0.0125, 0.0394] sex, age, birth date, deprivation index, 16 PCs
PPM011569 PGS002088
(portability-ldpred2_714.1)
PSS008014|
East Asian Ancestry|
1,754 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0226 [-0.0245, 0.0696] sex, age, birth date, deprivation index, 16 PCs
PPM011570 PGS002088
(portability-ldpred2_714.1)
PSS007799|
African Ancestry|
2,277 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): -0.0007 [-0.0419, 0.0406] sex, age, birth date, deprivation index, 16 PCs
PPM011571 PGS002088
(portability-ldpred2_714.1)
PSS008903|
African Ancestry|
3,634 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): -0.0214 [-0.054, 0.0112] sex, age, birth date, deprivation index, 16 PCs
PPM011567 PGS002088
(portability-ldpred2_714.1)
PSS008454|
Greater Middle Eastern Ancestry|
1,128 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Rheumatoid arthritis Partial Correlation (partial-r): 0.0403 [-0.0186, 0.099] sex, age, birth date, deprivation index, 16 PCs
PPM011572 PGS002089
(portability-ldpred2_715.2)
PSS009353|
European Ancestry|
18,262 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.0919 [0.0775, 0.1063] sex, age, birth date, deprivation index, 16 PCs
PPM011573 PGS002089
(portability-ldpred2_715.2)
PSS009127|
European Ancestry|
3,854 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.0476 [0.016, 0.0791] sex, age, birth date, deprivation index, 16 PCs
PPM011574 PGS002089
(portability-ldpred2_715.2)
PSS008681|
European Ancestry|
6,216 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.0596 [0.0348, 0.0844] sex, age, birth date, deprivation index, 16 PCs
PPM011576 PGS002089
(portability-ldpred2_715.2)
PSS008235|
South Asian Ancestry|
5,671 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.0424 [0.0163, 0.0684] sex, age, birth date, deprivation index, 16 PCs
PPM011575 PGS002089
(portability-ldpred2_715.2)
PSS008455|
Greater Middle Eastern Ancestry|
1,124 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Ankylosing spondylitis Partial Correlation (partial-r): 0.1631 [0.1051, 0.22] sex, age, birth date, deprivation index, 16 PCs
PPM011608 PGS002094
(portability-ldpred2_740)
PSS009359|
European Ancestry|
20,000 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0535 [0.0397, 0.0673] sex, age, birth date, deprivation index, 16 PCs
PPM011609 PGS002094
(portability-ldpred2_740)
PSS009133|
European Ancestry|
4,136 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0612 [0.0307, 0.0916] sex, age, birth date, deprivation index, 16 PCs
PPM011610 PGS002094
(portability-ldpred2_740)
PSS008687|
European Ancestry|
6,660 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0544 [0.0304, 0.0783] sex, age, birth date, deprivation index, 16 PCs
PPM011611 PGS002094
(portability-ldpred2_740)
PSS008461|
Greater Middle Eastern Ancestry|
1,200 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.025 [-0.0321, 0.082] sex, age, birth date, deprivation index, 16 PCs
PPM011612 PGS002094
(portability-ldpred2_740)
PSS008241|
South Asian Ancestry|
6,331 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0394 [0.0148, 0.064] sex, age, birth date, deprivation index, 16 PCs
PPM011613 PGS002094
(portability-ldpred2_740)
PSS008019|
East Asian Ancestry|
1,810 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): -0.0056 [-0.052, 0.0407] sex, age, birth date, deprivation index, 16 PCs
PPM011614 PGS002094
(portability-ldpred2_740)
PSS007805|
African Ancestry|
2,484 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.0412 [0.0017, 0.0806] sex, age, birth date, deprivation index, 16 PCs
PPM011615 PGS002094
(portability-ldpred2_740)
PSS008909|
African Ancestry|
3,924 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoarthrosis Partial Correlation (partial-r): 0.022 [-0.0094, 0.0534] sex, age, birth date, deprivation index, 16 PCs
PPM011616 PGS002095
(portability-ldpred2_743.1)
PSS009360|
European Ancestry|
19,982 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0268 [0.013, 0.0407] sex, age, birth date, deprivation index, 16 PCs
PPM011617 PGS002095
(portability-ldpred2_743.1)
PSS009134|
European Ancestry|
4,130 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0131 [-0.0174, 0.0437] sex, age, birth date, deprivation index, 16 PCs
PPM011618 PGS002095
(portability-ldpred2_743.1)
PSS008688|
European Ancestry|
6,657 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0248 sex, age, birth date, deprivation index, 16 PCs
PPM011619 PGS002095
(portability-ldpred2_743.1)
PSS008462|
Greater Middle Eastern Ancestry|
1,199 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0116 [-0.0455, 0.0687] sex, age, birth date, deprivation index, 16 PCs
PPM011620 PGS002095
(portability-ldpred2_743.1)
PSS008242|
South Asian Ancestry|
6,327 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): -0.0013 [-0.026, 0.0233] sex, age, birth date, deprivation index, 16 PCs
PPM011621 PGS002095
(portability-ldpred2_743.1)
PSS008020|
East Asian Ancestry|
1,808 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0077 [-0.0387, 0.054] sex, age, birth date, deprivation index, 16 PCs
PPM011622 PGS002095
(portability-ldpred2_743.1)
PSS007806|
African Ancestry|
2,483 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0261 [-0.0135, 0.0655] sex, age, birth date, deprivation index, 16 PCs
PPM011623 PGS002095
(portability-ldpred2_743.1)
PSS008910|
African Ancestry|
3,923 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis Partial Correlation (partial-r): 0.0012 [-0.0301, 0.0326] sex, age, birth date, deprivation index, 16 PCs
PPM012870 PGS002260
(PRS_RA)
PSS009586|
East Asian Ancestry|
740 individuals
PGP000286 |
Honda S et al. Arthritis Rheumatol (2022)
Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis OR (top vs 2nd quintile): 1.87 [1.11, 3.15]
PPM012871 PGS002260
(PRS_RA)
PSS009586|
East Asian Ancestry|
740 individuals
PGP000286 |
Honda S et al. Arthritis Rheumatol (2022)
Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis (age of onset <40 years) OR (top vs 2nd quintile): 6.29 [1.85, 21.4]
PPM012872 PGS002260
(PRS_RA)
PSS009586|
East Asian Ancestry|
740 individuals
PGP000286 |
Honda S et al. Arthritis Rheumatol (2022)
Reported Trait: Severe radiographic progression in patients with rheumatoid arthritis OR: 1.3 [1.13, 1.5] Age of onset, sex, ever-smoker, ACPAs positivity, rheumatoid factor positivity, BMI, periodontitis, use of methotrexate, use of bDMARD, HLA-DRB1 (Ser11)
PPM014781 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident severe radiographic osteoarthritis OR: 1.33 [1.12, 1.59]
PPM014756 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Prevalent radiographic osteoarthritis OR: 1.19 [1.1, 1.28]
PPM014757 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident radiographic osteoarthritis OR: 1.15 [1.05, 1.26]
PPM014758 PGS002728
(PRS_hip)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Prevalent radiographic osteoarthritis OR: 1.28 [0.98, 1.65]
PPM014759 PGS002728
(PRS_hip)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident radiographic osteoarthritis OR: 0.95 [0.82, 1.11]
PPM014766 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Prevalent clinical osteoarthritis OR: 1.3 [1.15, 1.46]
PPM014767 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident clinical osteoarthritis OR: 1.22 [0.98, 1.51]
PPM014768 PGS002728
(PRS_hip)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident clinical osteoarthritis OR: 0.92 [0.74, 1.14]
PPM014773 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Prevalent total hip replacement OR: 1.26 [1.12, 1.41]
PPM014774 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident total hip replacement OR: 1.28 [1.11, 1.48]
PPM014775 PGS002728
(PRS_hip)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident total hip replacement OR: 1.09 [0.79, 1.47]
PPM014779 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Radiographic osteoarthritis progression OR: 1.18 [1.09, 1.28]
PPM014783 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Radiographic osteoarthritis AUROC: 0.59 [0.56, 0.61] Age, sex
PPM014784 PGS002728
(PRS_hip)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Radiographic osteoarthritis AUROC: 0.62 [0.58, 0.65] Age, sex
PPM014785 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Clinical osteoarthritis AUROC: 0.62 [0.56, 0.68] Age, sex
PPM014786 PGS002728
(PRS_hip)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Clinical osteoarthritis AUROC: 0.53 [0.47, 0.59] Age, sex
PPM014787 PGS002728
(PRS_hip)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Total hip replacement AUROC: 0.66 [0.62, 0.70] Age, sex
PPM014788 PGS002728
(PRS_hip)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Total hip replacement AUROC: 0.64 [0.55, 0.73] Age, sex
PPM014760 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Prevalent radiographic osteoarthritis OR: 1.17 [1.1, 1.24]
PPM014771 PGS002729
(PRS_knee)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident clinical osteoarthritis OR: 1.26 [1.05, 1.52]
PPM014793 PGS002729
(PRS_knee)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Clinical osteoarthritis AUROC: 0.6 [0.55, 0.65] Age, sex, BMI
PPM014761 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident radiographic osteoarthritis OR: 1.15 [1.06, 1.24]
PPM014762 PGS002729
(PRS_knee)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Prevalent radiographic osteoarthritis OR: 1.27 [0.96, 1.68]
PPM014763 PGS002729
(PRS_knee)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident radiographic osteoarthritis OR: 1.09 [0.93, 1.29]
PPM014764 PGS002729
(PRS_knee)
PSS009890|
European Ancestry|
407 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Prevalent radiographic osteoarthritis OR: 1.02 [0.69, 1.53]
PPM014765 PGS002729
(PRS_knee)
PSS009890|
European Ancestry|
407 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident radiographic osteoarthritis OR: 1.04 [0.75, 1.45]
PPM014769 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Prevalent clinical osteoarthritis OR: 1.23 [1.12, 1.34]
PPM014770 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident clinical osteoarthritis OR: 1.13 [0.94, 1.37]
PPM014772 PGS002729
(PRS_knee)
PSS009890|
European Ancestry|
407 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident clinical osteoarthritis OR: 1.17 [0.8, 1.73]
PPM014776 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Prevalent total knee replacement OR: 1.3 [0.99, 1.71]
PPM014777 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident total knee replacement OR: 1.56 [1.27, 1.91]
PPM014778 PGS002729
(PRS_knee)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident total knee replacement OR: 1.16 [0.65, 2.17]
PPM014780 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Radiographic osteoarthritis progression OR: 1.18 [1.11, 1.25]
PPM014782 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Incident severe radiographic osteoarthritis OR: 1.3 [1.04, 1.63]
PPM014789 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Radiographic osteoarthritis AUROC: 0.6 [0.58, 0.63] Age, sex, BMI
PPM014790 PGS002729
(PRS_knee)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Radiographic osteoarthritis AUROC: 0.57 [0.53, 0.62] Age, sex, BMI
PPM014791 PGS002729
(PRS_knee)
PSS009890|
European Ancestry|
407 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Radiographic osteoarthritis AUROC: 0.53 [0.44, 0.63] Age, BMI
PPM014792 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Clinical osteoarthritis AUROC: 0.66 [0.61, 0.71] Age, sex, BMI
PPM014794 PGS002729
(PRS_knee)
PSS009890|
European Ancestry|
407 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Clinical osteoarthritis AUROC: 0.52 [0.41, 0.63] Age, BMI
PPM014795 PGS002729
(PRS_knee)
PSS009891|
European Ancestry|
14,926 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Total hip replacement AUROC: 0.66 [0.61, 0.71] Age, sex, BMI
PPM014796 PGS002729
(PRS_knee)
PSS009889|
European Ancestry|
1,002 individuals
PGP000336 |
Sedaghati-Khayat B et al. Arthritis Rheumatol (2022)
Reported Trait: Total hip replacement AUROC: 0.65 [0.49, 0.82] Age, sex, BMI
PPM014915 PGS002745
(metaPGS_RA)
PSS009927|
Multi-ancestry (including European)|
7,460 individuals
PGP000357 |
Ishigaki K et al. Nat Genet (2022)
Reported Trait: Rheumatoid arthritis AUROC: 0.65 Liability R2: 0.054 Sex, Genotype PCs Performance metrics are the mean values across eave-one-cohort-out cross-validation folds
PPM014916 PGS002745
(metaPGS_RA)
PSS009930|
European Ancestry|
3,887 individuals
PGP000357 |
Ishigaki K et al. Nat Genet (2022)
Reported Trait: Rheumatoid arthritis AUROC: 0.66 Liability R2: 0.059 Sex, Genotype PCs Performance metrics are the mean values across eave-one-cohort-out cross-validation folds
PPM014917 PGS002745
(metaPGS_RA)
PSS009929|
East Asian Ancestry|
21,704 individuals
PGP000357 |
Ishigaki K et al. Nat Genet (2022)
Reported Trait: Rheumatoid arthritis AUROC: 0.66 Liability R2: 0.057 Sex, Genotype PCs Performance metrics are the mean values across eave-one-cohort-out cross-validation folds
PPM014918 PGS002745
(metaPGS_RA)
PSS009928|
Multi-ancestry (excluding European)|
1,304 individuals
PGP000357 |
Ishigaki K et al. Nat Genet (2022)
Reported Trait: Rheumatoid arthritis AUROC: 0.59 Liability R2: 0.018 Sex, Genotype PCs Performance metrics are the mean values across eave-one-cohort-out cross-validation folds
PPM014939 PGS002749
(PRS10_TKR)
PSS009936|
European Ancestry|
1,422 individuals
PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
Reported Trait: Knee replacement OR: 1.13 [1.07, 1.2] Age, sex, body mass index, education, and index of relative socioeconomic advantage and disadvantage
PPM014940 PGS002750
(PRS37_THR)
PSS009935|
European Ancestry|
1,257 individuals
PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
Reported Trait: Hip replacement OR: 1.23 [1.16, 1.3] Age, sex, body mass index, education, and index of relative socioeconomic advantage and disadvantage
PPM014941 PGS002750
(PRS37_THR)
PSS009935|
European Ancestry|
1,257 individuals
PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
Reported Trait: Hip replacement in men OR: 1.15 [1.06, 1.26] Age, body mass index, education, and index of relative socioeconomic advantage and disadvantage
PPM014942 PGS002750
(PRS37_THR)
PSS009935|
European Ancestry|
1,257 individuals
PGP000362 |
Lacaze P et al. Arthritis Rheumatol (2022)
Reported Trait: Hip replacement in women OR: 1.3 [1.2, 1.4] Age, body mass index, education, and index of relative socioeconomic advantage and disadvantage
PPM014963 PGS002763
(Hip_osteoarthritis_prscs)
PSS009939|
European Ancestry|
39,444 individuals
PGP000364 |
Mars N et al. Am J Hum Genet (2022)
Reported Trait: Hip osteoarthritis OR: 1.38 [1.31, 1.46] age, sex, 10 PCs, technical covariates
PPM014967 PGS002767
(Knee_osteoarthritis_prscs)
PSS009939|
European Ancestry|
39,444 individuals
PGP000364 |
Mars N et al. Am J Hum Genet (2022)
Reported Trait: Knee osteoarthritis OR: 1.35 [1.3, 1.4] age, sex, 10 PCs, technical covariates
PPM014968 PGS002768
(BMD_prscs)
PSS009939|
European Ancestry|
39,444 individuals
PGP000364 |
Mars N et al. Am J Hum Genet (2022)
Reported Trait: Osteoporosis OR: 1.31 [1.25, 1.38] age, sex, 10 PCs, technical covariates
PPM014969 PGS002769
(Rheumatoid_arthritis_prscs)
PSS009939|
European Ancestry|
39,444 individuals
PGP000364 |
Mars N et al. Am J Hum Genet (2022)
Reported Trait: Seropositive rheumatoid arthritis OR: 1.72 [1.61, 1.83] age, sex, 10 PCs, technical covariates
PPM017073 PGS003420
(PRS100_PRScs)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.7886
PPM017074 PGS003421
(PRS16_C+T)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.7876
PPM017075 PGS003422
(PRS16_PRSice2)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.7876
PPM017076 PGS003423
(PRS100_Lassosum)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.7754
PPM017077 PGS003424
(PRS100_LDpred2)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis AUROC: 0.7605
PPM020015 PGS003994
(dbslmm.auto.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.33393 [1.28094638, 1.3890998]
β: 0.28813 [0.24759916, 0.32865591]
AUROC: 0.58064 [0.56883718, 0.59243732] : 0.01224 [0.00905012, 0.0158579] 0 beta = log(or)/sd_pgs
PPM020017 PGS003994
(dbslmm.auto.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.37351 [1.09734382, 1.71919027]
β: 0.31737 [0.09289255, 0.54185341]
AUROC: 0.57062 [0.49087135, 0.65037199] : 0.01113 [0.000312, 0.040902] 0 beta = log(or)/sd_pgs
PPM020018 PGS003994
(dbslmm.auto.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.1176 [1.05475987, 1.18418315]
β: 0.11118 [0.05331313, 0.16905321]
AUROC: 0.52923 [0.5116339, 0.54683125] : 0.0019 [0.000371, 0.00466991] 0 beta = log(or)/sd_pgs
PPM020019 PGS003994
(dbslmm.auto.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.82399 [1.59169421, 2.09018269]
β: 0.60103 [0.46479899, 0.73725147]
AUROC: 0.65883 [0.61913538, 0.6985174] : 0.05369 [0.03020613, 0.08591409] 0 beta = log(or)/sd_pgs
PPM020016 PGS003994
(dbslmm.auto.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.50841 [1.47749798, 1.53996605]
β: 0.41106 [0.3903501, 0.43176037]
AUROC: 0.61202 [0.60619063, 0.61785875] : 0.02501 [0.02245787, 0.02749797] 0 beta = log(or)/sd_pgs
PPM020050 PGS004010
(lassosum.auto.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.32987 [1.28121824, 1.38036919]
β: 0.28508 [0.24781138, 0.32235099]
AUROC: 0.58517 [0.5735, 0.59683621] : 0.01384 [0.01026836, 0.01752212] 0 beta = log(or)/sd_pgs
PPM020051 PGS004010
(lassosum.auto.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.49732 [1.46602685, 1.52927706]
β: 0.40368 [0.38255592, 0.42479511]
AUROC: 0.60802 [0.60210105, 0.6139434] : 0.02326 [0.02088065, 0.0257906] 0 beta = log(or)/sd_pgs
PPM020052 PGS004010
(lassosum.auto.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.28607 [1.08009867, 1.53131211]
β: 0.25159 [0.0770524, 0.42612496]
AUROC: 0.59832 [0.52394235, 0.67270553] : 0.01158 [0.00106957, 0.04053787] 0 beta = log(or)/sd_pgs
PPM020053 PGS004010
(lassosum.auto.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.18691 [1.12316952, 1.25426353]
β: 0.17135 [0.11615461, 0.22654857]
AUROC: 0.55861 [0.54216624, 0.57505125] : 0.00494 [0.00224141, 0.008649] 0 beta = log(or)/sd_pgs
PPM020054 PGS004010
(lassosum.auto.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.59047 [1.42931885, 1.76979456]
β: 0.46403 [0.357198, 0.57086347]
AUROC: 0.6696 [0.63218416, 0.70702386] : 0.05578 [0.03219308, 0.08912121] 0 beta = log(or)/sd_pgs
PPM020055 PGS004021
(lassosum.CV.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.46364 [1.40722648, 1.52232499]
β: 0.38093 [0.34162073, 0.42023876]
AUROC: 0.60294 [0.59126234, 0.6146234] : 0.02295 [0.01792423, 0.02800557] 0 beta = log(or)/sd_pgs
PPM020056 PGS004021
(lassosum.CV.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.61006 [1.57707721, 1.6437293]
β: 0.47627 [0.45557327, 0.49696762]
AUROC: 0.63039 [0.62463626, 0.63613412] : 0.03371 [0.03082787, 0.03667513] 0 beta = log(or)/sd_pgs
PPM020057 PGS004021
(lassosum.CV.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.91213 [1.49624529, 2.4436175]
β: 0.64822 [0.40295883, 0.89347952]
AUROC: 0.69067 [0.62429924, 0.75703169] : 0.03819 [0.01668401, 0.0690534] 0 beta = log(or)/sd_pgs
PPM020058 PGS004021
(lassosum.CV.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.4387 [1.3566017, 1.52577159]
β: 0.36374 [0.30498282, 0.42250024]
AUROC: 0.60312 [0.58631707, 0.61991468] : 0.01973 [0.01358075, 0.02702473] 0 beta = log(or)/sd_pgs
PPM020059 PGS004021
(lassosum.CV.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 2.11267 [1.86259241, 2.39632917]
β: 0.74795 [0.62196928, 0.87393805]
AUROC: 0.71102 [0.67560891, 0.74643625] : 0.09939 [0.0673612, 0.13982338] 0 beta = log(or)/sd_pgs
PPM020001 PGS004049
(ldpred2.CV.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.63972 [1.60628474, 1.67385776]
β: 0.49453 [0.47392389, 0.515131]
AUROC: 0.6351 [0.62933904, 0.64086446] : 0.0367 [0.03357391, 0.04012387] 0 beta = log(or)/sd_pgs
PPM020002 PGS004049
(ldpred2.CV.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.9896 [1.59472086, 2.48224985]
β: 0.68793 [0.46669871, 0.90916534]
AUROC: 0.70565 [0.63333493, 0.77796963] : 0.05367 [0.02290313, 0.09716264] 0 beta = log(or)/sd_pgs
PPM020003 PGS004049
(ldpred2.CV.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.54092 [1.45306104, 1.63408316]
β: 0.43238 [0.37367239, 0.49108189]
AUROC: 0.61952 [0.60270134, 0.636339] : 0.02797 [0.0211408, 0.03646128] 0 beta = log(or)/sd_pgs
PPM020004 PGS004049
(ldpred2.CV.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 2.36914 [2.07577111, 2.70396438]
β: 0.86253 [0.73033271, 0.99471898]
AUROC: 0.72826 [0.69173398, 0.76478209] : 0.122 [0.08216417, 0.16529108] 0 beta = log(or)/sd_pgs
PPM020000 PGS004049
(ldpred2.CV.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.55377 [1.4943584, 1.61555387]
β: 0.44069 [0.40169695, 0.47967785]
AUROC: 0.62089 [0.60918562, 0.63258519] : 0.03138 [0.02545406, 0.03718143] 0 beta = log(or)/sd_pgs
PPM020035 PGS004064
(megaprs.auto.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.52285 [1.46263457, 1.58555171]
β: 0.42059 [0.38023931, 0.46093243]
AUROC: 0.61325 [0.60161044, 0.62487979] : 0.02644 [0.02106118, 0.03159975] 0 beta = log(or)/sd_pgs
PPM020036 PGS004064
(megaprs.auto.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.6765 [1.64253856, 1.71116433]
β: 0.51671 [0.49624295, 0.53717403]
AUROC: 0.64169 [0.63597003, 0.64740127] : 0.04068 [0.03737711, 0.04388012] 0 beta = log(or)/sd_pgs
PPM020037 PGS004064
(megaprs.auto.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 2.16519 [1.63058972, 2.87505923]
β: 0.77251 [0.48894174, 1.05607327]
AUROC: 0.68659 [0.62306752, 0.75011928] : 0.04033 [0.01968338, 0.06955001] 0 beta = log(or)/sd_pgs
PPM020038 PGS004064
(megaprs.auto.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.52777 [1.44093306, 1.6198353]
β: 0.42381 [0.36529086, 0.48232448]
AUROC: 0.615 [0.59804531, 0.63195557] : 0.02702 [0.01945086, 0.03541182] 0 beta = log(or)/sd_pgs
PPM020039 PGS004064
(megaprs.auto.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 2.12896 [1.86473669, 2.4306247]
β: 0.75563 [0.62311986, 0.8881483]
AUROC: 0.71237 [0.67693105, 0.74780668] : 0.09048 [0.06089994, 0.12628899] 0 beta = log(or)/sd_pgs
PPM020030 PGS004079
(megaprs.CV.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.50199 [1.44431953, 1.56196832]
β: 0.40679 [0.36763829, 0.44594677]
AUROC: 0.60873 [0.59700811, 0.62044991] : 0.02641 [0.02099026, 0.03200156] 0 beta = log(or)/sd_pgs
PPM020031 PGS004079
(megaprs.CV.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.61696 [1.5839576, 1.65065666]
β: 0.48055 [0.45992653, 0.50117319]
AUROC: 0.63145 [0.62565031, 0.63723984] : 0.03458 [0.03148347, 0.03790002] 0 beta = log(or)/sd_pgs
PPM020032 PGS004079
(megaprs.CV.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 2.0218 [1.62249081, 2.51937283]
β: 0.70399 [0.48396251, 0.92400999]
AUROC: 0.71409 [0.65011341, 0.77806995] : 0.05539 [0.02757678, 0.09737164] 0 beta = log(or)/sd_pgs
PPM020033 PGS004079
(megaprs.CV.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.60515 [1.51334744, 1.70252754]
β: 0.47322 [0.41432404, 0.53211394]
AUROC: 0.63076 [0.61433544, 0.64719353] : 0.03332 [0.02538049, 0.04297958] 0 beta = log(or)/sd_pgs
PPM020034 PGS004079
(megaprs.CV.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 2.22137 [1.95736288, 2.5209968]
β: 0.79813 [0.6715981, 0.92465438]
AUROC: 0.71931 [0.68214811, 0.75647815] : 0.11294 [0.0751487, 0.15730633] 0 beta = log(or)/sd_pgs
PPM020045 PGS004094
(prscs.auto.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.43309 [1.37789918, 1.49048299]
β: 0.35983 [0.32056001, 0.39910022]
AUROC: 0.60175 [0.58999494, 0.61350437] : 0.01993 [0.01570594, 0.02462764] 0 beta = log(or)/sd_pgs
PPM020046 PGS004094
(prscs.auto.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.64768 [1.61352054, 1.68256451]
β: 0.49937 [0.47841846, 0.52031912]
AUROC: 0.63372 [0.62788781, 0.63955506] : 0.03632 [0.03309896, 0.03953108] 0 beta = log(or)/sd_pgs
PPM020047 PGS004094
(prscs.auto.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.45841 [1.19873228, 1.77432944]
β: 0.37734 [0.18126456, 0.57342257]
AUROC: 0.60742 [0.53398957, 0.68084175] : 0.01948 [0.00432876, 0.05204534] 0 beta = log(or)/sd_pgs
PPM020048 PGS004094
(prscs.auto.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.30074 [1.2314019, 1.37398385]
β: 0.26293 [0.20815328, 0.31771444]
AUROC: 0.58564 [0.56934416, 0.60192786] : 0.01181 [0.00719488, 0.01742899] 0 beta = log(or)/sd_pgs
PPM020049 PGS004094
(prscs.auto.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.88898 [1.67167849, 2.13453009]
β: 0.63604 [0.5138282, 0.75824653]
AUROC: 0.69466 [0.65809177, 0.73122596] : 0.07313 [0.04487877, 0.10829372] 0 beta = log(or)/sd_pgs
PPM020040 PGS004103
(prscs.CV.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.39977 [1.34410643, 1.45773885]
β: 0.33631 [0.29572943, 0.3768865]
AUROC: 0.5924 [0.58070208, 0.60409508] : 0.01668 [0.01284464, 0.02085219] 0 beta = log(or)/sd_pgs
PPM020041 PGS004103
(prscs.CV.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.43354 [1.40427497, 1.46341096]
β: 0.36015 [0.33952114, 0.38076998]
AUROC: 0.60119 [0.59539073, 0.60698337] : 0.01933 [0.01709073, 0.021498] 0 beta = log(or)/sd_pgs
PPM020042 PGS004103
(prscs.CV.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.62378 [1.29975822, 2.02858217]
β: 0.48476 [0.26217827, 0.70733711]
AUROC: 0.64719 [0.57521551, 0.71916706] : 0.0251 [0.00821845, 0.05577828] 0 beta = log(or)/sd_pgs
PPM020043 PGS004103
(prscs.CV.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.24983 [1.17898128, 1.32493323]
β: 0.22301 [0.16465075, 0.28136206]
AUROC: 0.56468 [0.54783481, 0.58151937] : 0.0075 [0.00402557, 0.01180133] 0 beta = log(or)/sd_pgs
PPM020044 PGS004103
(prscs.CV.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.9189 [1.67929657, 2.19269289]
β: 0.65175 [0.51837499, 0.78513042]
AUROC: 0.67899 [0.6419829, 0.71598959] : 0.06493 [0.04215202, 0.09455987] 0 beta = log(or)/sd_pgs
PPM020005 PGS004118
(pt_clump.auto.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.33056 [1.27927587, 1.3839026]
β: 0.2856 [0.24629419, 0.32490748]
AUROC: 0.57951 [0.56779004, 0.5912348] : 0.01289 [0.00942678, 0.01683411] 0 beta = log(or)/sd_pgs
PPM020006 PGS004118
(pt_clump.auto.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.40296 [1.37512281, 1.43135987]
β: 0.33858 [0.31854304, 0.35862495]
AUROC: 0.59425 [0.58836034, 0.60013257] : 0.01808 [0.01603989, 0.02043251] 0 beta = log(or)/sd_pgs
PPM020007 PGS004118
(pt_clump.auto.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.70576 [1.31671088, 2.20977427]
β: 0.53401 [0.27513687, 0.79289037]
AUROC: 0.65379 [0.59209129, 0.71549218] : 0.02382 [0.00843075, 0.05003813] 0 beta = log(or)/sd_pgs
PPM020008 PGS004118
(pt_clump.auto.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.30274 [1.23029942, 1.37944872]
β: 0.26447 [0.20725757, 0.32168394]
AUROC: 0.57047 [0.55330355, 0.58764034] : 0.01098 [0.00635806, 0.01667243] 0 beta = log(or)/sd_pgs
PPM020009 PGS004118
(pt_clump.auto.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.56663 [1.37347647, 1.78694216]
β: 0.44893 [0.31734509, 0.58050587]
AUROC: 0.62337 [0.58200096, 0.66473232] : 0.03261 [0.0140955, 0.05548662] 0 beta = log(or)/sd_pgs
PPM020010 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.34749 [1.29508225, 1.40201468]
β: 0.29824 [0.25857421, 0.33791026]
AUROC: 0.58105 [0.56930556, 0.59279972] : 0.0138 [0.01033525, 0.01782333] 0 beta = log(or)/sd_pgs
PPM020011 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.43562 [1.40681814, 1.46501743]
β: 0.3616 [0.34133052, 0.38186714]
AUROC: 0.59988 [0.59403334, 0.60572738] : 0.02017 [0.01796729, 0.0226397] 0 beta = log(or)/sd_pgs
PPM020012 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.54617 [1.19528898, 2.00006106]
β: 0.43578 [0.17838798, 0.69317771]
AUROC: 0.6263 [0.55995128, 0.69265647] : 0.01611 [0.00346998, 0.03792919] 0 beta = log(or)/sd_pgs
PPM020013 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.33067 [1.25591817, 1.40986302]
β: 0.28568 [0.22786692, 0.34349255]
AUROC: 0.57616 [0.55915512, 0.59316854] : 0.01255 [0.00747678, 0.01866845] 0 beta = log(or)/sd_pgs
PPM020014 PGS004133
(pt_clump_nested.CV.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.49068 [1.30391606, 1.70419754]
β: 0.39923 [0.26537209, 0.53309435]
AUROC: 0.60812 [0.56762836, 0.64860873] : 0.02494 [0.01039785, 0.04545545] 0 beta = log(or)/sd_pgs
PPM020020 PGS004148
(sbayesr.auto.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.39911 [1.3453147, 1.45504863]
β: 0.33583 [0.29662796, 0.37503932]
AUROC: 0.5916 [0.57985369, 0.6033368] : 0.01793 [0.01361181, 0.02247244] 0 beta = log(or)/sd_pgs
PPM020021 PGS004148
(sbayesr.auto.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.62873 [1.5962079, 1.66190947]
β: 0.4878 [0.46763075, 0.50796722]
AUROC: 0.63399 [0.62818932, 0.6397817] : 0.03731 [0.0341354, 0.04065053] 0 beta = log(or)/sd_pgs
PPM020022 PGS004148
(sbayesr.auto.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.86907 [1.45549233, 2.40017231]
β: 0.62544 [0.37534421, 0.87554053]
AUROC: 0.67317 [0.61055743, 0.73578134] : 0.03526 [0.01406596, 0.06823395] 0 beta = log(or)/sd_pgs
PPM020023 PGS004148
(sbayesr.auto.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.46527 [1.38341272, 1.55196664]
β: 0.38204 [0.32455343, 0.43952293]
AUROC: 0.60487 [0.58809209, 0.62164016] : 0.02273 [0.01613462, 0.03055882] 0 beta = log(or)/sd_pgs
PPM020024 PGS004148
(sbayesr.auto.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.74045 [1.52359433, 1.98817059]
β: 0.55414 [0.42107223, 0.68721491]
AUROC: 0.66211 [0.62585476, 0.69836134] : 0.04857 [0.02861608, 0.07522105] 0 beta = log(or)/sd_pgs
PPM020025 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
PSS011222|
European Ancestry|
199,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.64114 [1.57821035, 1.70658848]
β: 0.49539 [0.45629151, 0.53449634]
AUROC: 0.63353 [0.62188573, 0.645168] : 0.03944 [0.03314538, 0.04625298] 0 beta = log(or)/sd_pgs
PPM020026 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
PSS011233|
European Ancestry|
388,890 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.75402 [1.71840512, 1.79036854]
β: 0.56191 [0.5413966, 0.58242149]
AUROC: 0.65279 [0.64709296, 0.6584935] : 0.04802 [0.0444714, 0.05161881] 0 beta = log(or)/sd_pgs
PPM020027 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
PSS011246|
South Asian Ancestry|
44,057 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 2.39078 [1.89563819, 3.0152594]
β: 0.87162 [0.63955556, 1.10368586]
AUROC: 0.74329 [0.67891271, 0.80767425] : 0.07939 [0.04017912, 0.13128156] 0 beta = log(or)/sd_pgs
PPM020028 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
PSS011262|
European Ancestry|
66,865 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 1.6676 [1.57316173, 1.76770414]
β: 0.51138 [0.45308744, 0.56968161]
AUROC: 0.64052 [0.62389168, 0.65713902] : 0.03977 [0.03083288, 0.04944259] 0 beta = log(or)/sd_pgs
PPM020029 PGS004163
(UKBB_EnsPGS.GCST90013534.RA)
PSS011275|
European Ancestry|
90,274 individuals
PGP000517 |
Monti R et al. Am J Hum Genet (2024)
Reported Trait: Seropositive RA OR: 2.46183 [2.16199209, 2.8032592]
β: 0.90091 [0.77103006, 1.03078274]
AUROC: 0.74695 [0.71319269, 0.78070209] : 0.13759 [0.09865689, 0.18374268] 0 beta = log(or)/sd_pgs
PPM020323 PGS004255
(GenoBoost_rheumatoid_arthritis_0)
PSS011342|
European Ancestry|
67,428 individuals
PGP000546 |
Ohta R et al. Nat Commun (2024)
Reported Trait: Rheumatoid arthritis AUROC: 0.66209 Covariate-adjusted pseudo-R2: 0.01285
AUPRC: 0.04621
age, sex, PC1-10
PPM020324 PGS004256
(GenoBoost_rheumatoid_arthritis_1)
PSS011342|
European Ancestry|
67,428 individuals
PGP000546 |
Ohta R et al. Nat Commun (2024)
Reported Trait: Rheumatoid arthritis AUROC: 0.66212 Covariate-adjusted pseudo-R2: 0.01305
AUPRC: 0.04649
age, sex, PC1-10
PPM020325 PGS004257
(GenoBoost_rheumatoid_arthritis_2)
PSS011342|
European Ancestry|
67,428 individuals
PGP000546 |
Ohta R et al. Nat Commun (2024)
Reported Trait: Rheumatoid arthritis AUROC: 0.66087 AUPRC: 0.04561
Covariate-adjusted pseudo-R2: 0.01191
age, sex, PC1-10
PPM020326 PGS004258
(GenoBoost_rheumatoid_arthritis_3)
PSS011342|
European Ancestry|
67,428 individuals
PGP000546 |
Ohta R et al. Nat Commun (2024)
Reported Trait: Rheumatoid arthritis AUROC: 0.6639 Covariate-adjusted pseudo-R2: 0.01382
AUPRC: 0.04737
age, sex, PC1-10
PPM020327 PGS004259
(GenoBoost_rheumatoid_arthritis_4)
PSS011342|
European Ancestry|
67,428 individuals
PGP000546 |
Ohta R et al. Nat Commun (2024)
Reported Trait: Rheumatoid arthritis AUROC: 0.66128 Covariate-adjusted pseudo-R2: 0.01258
AUPRC: 0.04632
age, sex, PC1-10
PPM020440 PGS004326
(PRS154_RA)
PSS011363|
European Ancestry|
342,973 individuals
PGP000560 |
Zhang J et al. Environ Health Perspect (2023)
Reported Trait: Incident rheumatoid arthritis HR: 1.22 [1.17, 1.27] age, sex, UK Biobank assessment center, household income, education level, smoking status, body mass index, alcohol consumption, sedentary time, physical activity duration, healthy diet score, first 10 genetic principal components, and genotyping batch.
PPM020441 PGS004326
(PRS154_RA)
PSS011363|
European Ancestry|
342,973 individuals
PGP000560 |
Zhang J et al. Environ Health Perspect (2023)
Reported Trait: Incident rheumatoid arthritis with air pollution Hazard ratio (HR, high air pollution and PRS in top tertile vs low air pollution and PRS in bottom tertile): 1.73 [1.39, 2.17] age, sex, UK Biobank assessment center, household income, education level, smoking status, body mass index, alcohol consumption, sedentary time, physical activity duration, healthy diet score, first 10 genetic principal components, and genotyping batch.
PPM020592 PGS004477
(disease.M13.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M13 (Other arthritis) OR: 1.1956
PPM020593 PGS004478
(disease.M16.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M16 (Coxarthrosis [arthrosis of hip]) OR: 1.29595
PPM020594 PGS004479
(disease.M17.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M17 (Gonarthrosis [arthrosis of knee]) OR: 1.32326
PPM020595 PGS004480
(disease.M19.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M19 (Other arthrosis) OR: 1.21103
PPM020598 PGS004483
(disease.M25.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M25 (Other joint disorders, not elsewhere classified) OR: 1.07361
PPM020599 PGS004484
(disease.M47.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M47 (Spondylosis) OR: 1.20173
PPM020600 PGS004485
(disease.M48.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M48 (Other spondylopathies) OR: 1.18572
PPM020601 PGS004486
(disease.M51.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M51 (Other intervertebral disk disorders) OR: 1.18281
PPM020605 PGS004490
(disease.M81.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M81 (Osteoporosis without pathological fracture) OR: 1.17552
PPM020610 PGS004495
(disease.osteoporosis.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: Osteoporosis OR: 1.19793
PPM020662 PGS004547
(meta.M13.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M13 (Other arthritis) OR: 1.2622
PPM020663 PGS004548
(meta.M16.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M16 (Coxarthrosis [arthrosis of hip]) OR: 1.21626
PPM020664 PGS004549
(meta.M17.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M17 (Gonarthrosis [arthrosis of knee]) OR: 1.36669
PPM020665 PGS004550
(meta.M19.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M19 (Other arthrosis) OR: 1.24824
PPM020668 PGS004553
(meta.M25.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M25 (Other joint disorders, not elsewhere classified) OR: 1.11501
PPM020669 PGS004554
(meta.M47.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M47 (Spondylosis) OR: 1.23056
PPM020670 PGS004555
(meta.M48.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M48 (Other spondylopathies) OR: 1.1791
PPM020671 PGS004556
(meta.M51.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M51 (Other intervertebral disk disorders) OR: 1.1419
PPM020675 PGS004560
(meta.M81.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: M81 (Osteoporosis without pathological fracture) OR: 1.32082
PPM020680 PGS004565
(meta.osteoporosis.score)
PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: Osteoporosis OR: 1.32822
PPM021034 PGS004809
(osteoporosis_PRSmix_eur)
PSS011465|
European Ancestry|
9,462 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Osteoporosis Incremental R2 (Full model versus model with only covariates): 0.011 [0.007, 0.015] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021035 PGS004810
(osteoporosis_PRSmixPlus_eur)
PSS011465|
European Ancestry|
9,462 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Osteoporosis Incremental R2 (Full model versus model with only covariates): 0.022 [0.016, 0.028] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021042 PGS004817
(RA_PRSmix_eur)
PSS011465|
European Ancestry|
9,462 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Rheumatoid Arthritis Incremental R2 (Full model versus model with only covariates): 0.008 [0.004, 0.012] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021043 PGS004818
(RA_PRSmix_sas)
PSS011474|
South Asian Ancestry|
8,837 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Rheumatoid Arthritis Incremental R2 (Full model versus model with only covariates): 0.008 [0.005, 0.012] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021044 PGS004819
(RA_PRSmixPlus_eur)
PSS011465|
European Ancestry|
9,462 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Rheumatoid Arthritis Incremental R2 (Full model versus model with only covariates): 0.011 [0.007, 0.015] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021045 PGS004820
(RA_PRSmixPlus_sas)
PSS011474|
South Asian Ancestry|
8,837 individuals
PGP000604 |
Truong B et al. Cell Genom (2024)
Reported Trait: Rheumatoid Arthritis Incremental R2 (Full model versus model with only covariates): 0.009 [0.005, 0.013] age, sex, PC1, PC2, PC3, PC4, PC5, PC6, PC7, PC8, PC9, PC10 Incremental R2 (Full model versus model with only covariates)
PPM021165 PGS004873
(INTERVENE_MegaPRS_RA)
PSS011635|
European Ancestry|
447,332 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident RA HR: 1.87 [1.76, 1.99] PCs 1-10
PPM021166 PGS004873
(INTERVENE_MegaPRS_RA)
PSS011634|
European Ancestry|
37,986 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident RA HR: 2.16 [1.96, 2.37] C-index: 0.71 [0.68, 0.74] PCs 1-10
PPM021167 PGS004873
(INTERVENE_MegaPRS_RA)
PSS011633|
European Ancestry|
69,715 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident RA HR: 1.59 [1.49, 1.68] C-index: 0.64 [0.62, 0.66] PCs 1-10
PPM021168 PGS004873
(INTERVENE_MegaPRS_RA)
PSS011632|
European Ancestry|
29,427 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident RA HR: 2.27 [1.81, 2.84] C-index: 0.73 [0.66, 0.8] PCs 1-10
PPM021169 PGS004873
(INTERVENE_MegaPRS_RA)
PSS011630|
European Ancestry|
44,188 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident RA HR: 2.13 [1.65, 2.75] PCs 1-10
PPM021170 PGS004873
(INTERVENE_MegaPRS_RA)
PSS011631|
European Ancestry|
7,018 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident RA HR: 1.83 [1.14, 2.93] C-index: 0.85 [0.77, 0.92] PCs 1-10
PPM021171 PGS004873
(INTERVENE_MegaPRS_RA)
PSS011629|
European Ancestry|
412,090 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident RA HR: 1.65 [1.62, 1.69] C-index: 0.65 [0.65, 0.66] PCs 1-10
PPM021172 PGS004873
(INTERVENE_MegaPRS_RA)
PSS011628|
European Ancestry|
199,868 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident RA HR: 1.43 [1.38, 1.49] C-index: 0.61 [0.6, 0.62] PCs 1-10
PPM021231 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
PSS011593|
European Ancestry|
37,024 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident hip osteoarthritis HR: 1.16 [1.13, 1.2] C-index: 0.55 [0.54, 0.56] PCs 1-10
PPM021232 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
PSS011592|
European Ancestry|
69,715 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident hip osteoarthritis HR: 1.33 [1.29, 1.37] C-index: 0.58 [0.57, 0.59] PCs 1-10
PPM021233 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
PSS011591|
European Ancestry|
29,427 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident hip osteoarthritis HR: 1.46 [1.36, 1.56] C-index: 0.6 [0.58, 0.63] PCs 1-10
PPM021234 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
PSS011589|
European Ancestry|
44,188 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident hip osteoarthritis HR: 1.07 [0.88, 1.31] PCs 1-10
PPM021235 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
PSS011590|
European Ancestry|
7,018 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident hip osteoarthritis HR: 1.35 [1.24, 1.48] C-index: 0.6 [0.57, 0.63] PCs 1-10
PPM021236 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
PSS011588|
European Ancestry|
412,090 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident hip osteoarthritis HR: 1.4 [1.38, 1.42] C-index: 0.6 [0.6, 0.6] PCs 1-10
PPM021237 PGS004882
(INTERVENE_MegaPRS_Hip_osteoarthritis)
PSS011587|
European Ancestry|
199,868 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident hip osteoarthritis HR: 1.15 [1.13, 1.16] C-index: 0.57 [0.56, 0.57] PCs 1-10
PPM021238 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
PSS011600|
European Ancestry|
37,245 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident knee osteoarthritis HR: 1.19 [1.17, 1.22] C-index: 0.56 [0.55, 0.57] PCs 1-10
PPM021239 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
PSS011599|
European Ancestry|
69,715 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident knee osteoarthritis HR: 1.32 [1.28, 1.35] C-index: 0.58 [0.57, 0.59] PCs 1-10
PPM021240 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
PSS011598|
European Ancestry|
29,427 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident knee osteoarthritis HR: 1.37 [1.3, 1.44] C-index: 0.6 [0.58, 0.61] PCs 1-10
PPM021241 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
PSS011596|
European Ancestry|
44,188 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident knee osteoarthritis HR: 1.17 [1.1, 1.24] PCs 1-10
PPM021242 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
PSS011597|
European Ancestry|
7,018 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident knee osteoarthritis HR: 1.28 [1.17, 1.39] C-index: 0.6 [0.57, 0.62] PCs 1-10
PPM021243 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
PSS011595|
European Ancestry|
412,090 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident knee osteoarthritis HR: 1.32 [1.31, 1.34] C-index: 0.59 [0.58, 0.59] PCs 1-10
PPM021244 PGS004883
(INTERVENE_MegaPRS_Knee_osteoarthritis)
PSS011594|
European Ancestry|
199,868 individuals
PGP000618 |
Jermy B et al. Nat Commun (2024)
Reported Trait: Incident knee osteoarthritis HR: 1.17 [1.16, 1.18] C-index: 0.56 [0.56, 0.56] PCs 1-10
PPM022366 PGS005146
(Osteoporosis (PRS-CS; EAS))
PSS011922|
East Asian Ancestry|
58,611 individuals
PGP000704 |
Jung HU et al. Commun Biol (2025)
Reported Trait: Osteoporosis β: 1.09366 age, sex
PPM022375 PGS005155
(Osteoporosis (PRS-CSx; EAS+EUR))
PSS011922|
East Asian Ancestry|
58,611 individuals
PGP000704 |
Jung HU et al. Commun Biol (2025)
Reported Trait: Osteoporosis β: 1.14434 age, sex
PPM036596 PGS018416
(PRS_knee)
PSS012319|
European Ancestry|
163,987 individuals
PGP000833 |
Wei Y et al. Clin Nutr (2024)
Reported Trait: Knee osteoarthritis Hazard ratio (HR, high vs low tertile): 1.43 [1.34, 1.53] age, sex, BMI, education levels, Townsend deprivation index, physical activity, ethnic background, smoking status, drinking status, family history of diseases (hypertension, cardiovascular disease, and diabetes), depression, chondroitin product intake, 10 genetic principal components, genotype measurement batch, healthy dietary score and total energy intake
PPM036598 PGS018416
(PRS_knee)
PSS012319|
European Ancestry|
163,987 individuals
PGP000833 |
Wei Y et al. Clin Nutr (2024)
Reported Trait: Knee osteoarthritis x ultra-processed food (UPF) consumption interaction Hazard ratio (HR, high UPF consumption and high PRS vs. low UPF consumption and low PRS): 1.56 [1.37, 1.79] age, sex, BMI, education levels, Townsend deprivation index, physical activity, ethnic background, smoking status, drinking status, family history of diseases (hypertension, cardiovascular disease, and diabetes), depression, chondroitin product intake, 10 genetic principal components, genotype measurement batch, healthy dietary score and total energy intake
PPM036595 PGS018417
(PRS_hip)
PSS012319|
European Ancestry|
163,987 individuals
PGP000833 |
Wei Y et al. Clin Nutr (2024)
Reported Trait: Hip osteoarthritis Hazard ratio (HR, high vs low tertile): 1.76 [1.62, 1.9] age, sex, BMI, education levels, Townsend deprivation index, physical activity, ethnic background, smoking status, drinking status, family history of diseases (hypertension, cardiovascular disease, and diabetes), depression, chondroitin product intake, 10 genetic principal components, genotype measurement batch, healthy dietary score and total energy intake
PPM036597 PGS018417
(PRS_hip)
PSS012319|
European Ancestry|
163,987 individuals
PGP000833 |
Wei Y et al. Clin Nutr (2024)
Reported Trait: Hip osteoarthritis x ultra-processed food (UPF) consumption interaction Hazard ratio (HR, high UPF consumption and high PRS vs. low UPF consumption and low PRS): 1.82 [1.54, 2.15] age, sex, BMI, education levels, Townsend deprivation index, physical activity, ethnic background, smoking status, drinking status, family history of diseases (hypertension, cardiovascular disease, and diabetes), depression, chondroitin product intake, 10 genetic principal components, genotype measurement batch, healthy dietary score and total energy intake
PPM036998 PGS018816
(TPMI_274_Lassosum2)
PSS012731|
East Asian Ancestry|
19,681 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gout and other crystal arthropathies AUROC: 0.72592 : 0.15189 sex, age, array, PCs 1-10
PPM036999 PGS018817
(TPMI_274_LDpred2)
PSS012730|
East Asian Ancestry|
19,681 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gout and other crystal arthropathies AUROC: 0.72801 : 0.15577 sex, age, array, PCs 1-10
PPM037000 PGS018818
(TPMI_274_MegaPRS)
PSS012732|
East Asian Ancestry|
19,681 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gout and other crystal arthropathies AUROC: 0.71916 : 0.13938 sex, age, array, PCs 1-10
PPM037001 PGS018819
(TPMI_274_PRS-CS)
PSS012733|
East Asian Ancestry|
19,681 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gout and other crystal arthropathies AUROC: 0.72764 : 0.15465 sex, age, array, PCs 1-10
PPM037002 PGS018820
(TPMI_274_PRSmix+)
PSS012734|
East Asian Ancestry|
19,681 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gout and other crystal arthropathies AUROC: 0.73221 : 0.1608 sex, age, array, PCs 1-10
PPM037003 PGS018821
(TPMI_274_SBayesR)
PSS012735|
East Asian Ancestry|
19,681 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gout and other crystal arthropathies AUROC: 0.72428 : 0.14877 sex, age, array, PCs 1-10
PPM037452 PGS019270
(TPMI_475_Lassosum2)
PSS013173|
East Asian Ancestry|
16,060 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Chronic sinusitis AUROC: 0.64256 : 0.04727 sex, age, array, PCs 1-10
PPM037453 PGS019271
(TPMI_475_LDpred2)
PSS013172|
East Asian Ancestry|
16,060 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Chronic sinusitis AUROC: 0.6436 : 0.04727 sex, age, array, PCs 1-10
PPM037454 PGS019272
(TPMI_475_MegaPRS)
PSS013174|
East Asian Ancestry|
16,060 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Chronic sinusitis AUROC: 0.63977 : 0.0454 sex, age, array, PCs 1-10
PPM037455 PGS019273
(TPMI_475_PRS-CS)
PSS013175|
East Asian Ancestry|
16,060 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Chronic sinusitis AUROC: 0.64175 : 0.04626 sex, age, array, PCs 1-10
PPM037456 PGS019274
(TPMI_475_SBayesR)
PSS013176|
East Asian Ancestry|
16,060 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Chronic sinusitis AUROC: 0.64071 : 0.0455 sex, age, array, PCs 1-10
PPM037482 PGS019300
(TPMI_523_Lassosum2)
PSS013213|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingival and periodontal diseases AUROC: 0.657 : 0.08492 sex, age, array, PCs 1-10
PPM037483 PGS019301
(TPMI_523_LDpred2)
PSS013212|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingival and periodontal diseases AUROC: 0.6568 : 0.0849 sex, age, array, PCs 1-10
PPM037484 PGS019302
(TPMI_523_MegaPRS)
PSS013214|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingival and periodontal diseases AUROC: 0.656 : 0.08408 sex, age, array, PCs 1-10
PPM037485 PGS019303
(TPMI_523_PRS-CS)
PSS013215|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingival and periodontal diseases AUROC: 0.65669 : 0.08483 sex, age, array, PCs 1-10
PPM037486 PGS019304
(TPMI_523_SBayesR)
PSS013216|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingival and periodontal diseases AUROC: 0.65756 : 0.08524 sex, age, array, PCs 1-10
PPM037487 PGS019305
(TPMI_523.1_Lassosum2)
PSS013203|
East Asian Ancestry|
17,094 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingivitis AUROC: 0.709 : 0.0658 sex, age, array, PCs 1-10
PPM037488 PGS019306
(TPMI_523.1_LDpred2)
PSS013202|
East Asian Ancestry|
17,094 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingivitis AUROC: 0.70895 : 0.06566 sex, age, array, PCs 1-10
PPM037489 PGS019307
(TPMI_523.1_MegaPRS)
PSS013204|
East Asian Ancestry|
17,094 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingivitis AUROC: 0.70904 : 0.06565 sex, age, array, PCs 1-10
PPM037490 PGS019308
(TPMI_523.1_PRS-CS)
PSS013205|
East Asian Ancestry|
17,094 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingivitis AUROC: 0.70898 : 0.06564 sex, age, array, PCs 1-10
PPM037491 PGS019309
(TPMI_523.1_SBayesR)
PSS013206|
East Asian Ancestry|
17,094 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Gingivitis AUROC: 0.7094 : 0.06585 sex, age, array, PCs 1-10
PPM037492 PGS019310
(TPMI_523.3_Lassosum2)
PSS013208|
East Asian Ancestry|
18,181 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Periodontitis acute or chronic AUROC: 0.656 : 0.0783 sex, age, array, PCs 1-10
PPM037493 PGS019311
(TPMI_523.3_LDpred2)
PSS013207|
East Asian Ancestry|
18,181 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Periodontitis acute or chronic AUROC: 0.65561 : 0.07813 sex, age, array, PCs 1-10
PPM037494 PGS019312
(TPMI_523.3_MegaPRS)
PSS013209|
East Asian Ancestry|
18,181 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Periodontitis acute or chronic AUROC: 0.65536 : 0.07776 sex, age, array, PCs 1-10
PPM037495 PGS019313
(TPMI_523.3_PRS-CS)
PSS013210|
East Asian Ancestry|
18,181 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Periodontitis acute or chronic AUROC: 0.65564 : 0.0781 sex, age, array, PCs 1-10
PPM037496 PGS019314
(TPMI_523.3_SBayesR)
PSS013211|
East Asian Ancestry|
18,181 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Periodontitis acute or chronic AUROC: 0.65585 : 0.07835 sex, age, array, PCs 1-10
PPM037502 PGS019320
(TPMI_526.4_Lassosum2)
PSS013218|
East Asian Ancestry|
16,784 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Temporomandibular joint disorders AUROC: 0.65664 : 0.0097 sex, age, array, PCs 1-10
PPM037503 PGS019321
(TPMI_526.4_LDpred2)
PSS013217|
East Asian Ancestry|
16,784 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Temporomandibular joint disorders AUROC: 0.66218 : 0.01027 sex, age, array, PCs 1-10
PPM037504 PGS019322
(TPMI_526.4_MegaPRS)
PSS013219|
East Asian Ancestry|
16,784 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Temporomandibular joint disorders AUROC: 0.65431 : 0.00965 sex, age, array, PCs 1-10
PPM037505 PGS019323
(TPMI_526.4_PRS-CS)
PSS013220|
East Asian Ancestry|
16,784 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Temporomandibular joint disorders AUROC: 0.66017 : 0.00993 sex, age, array, PCs 1-10
PPM037506 PGS019324
(TPMI_526.4_SBayesR)
PSS013221|
East Asian Ancestry|
16,784 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Temporomandibular joint disorders AUROC: 0.65615 : 0.00968 sex, age, array, PCs 1-10
PPM037805 PGS019623
(TPMI_696.42_Lassosum2)
PSS013514|
East Asian Ancestry|
17,217 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Psoriatic arthropathy AUROC: 0.83174 : 0.03895 sex, age, array, PCs 1-10
PPM037806 PGS019624
(TPMI_696.42_LDpred2)
PSS013513|
East Asian Ancestry|
17,217 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Psoriatic arthropathy AUROC: 0.83711 : 0.04078 sex, age, array, PCs 1-10
PPM037807 PGS019625
(TPMI_696.42_MegaPRS)
PSS013515|
East Asian Ancestry|
17,217 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Psoriatic arthropathy AUROC: 0.79524 : 0.03003 sex, age, array, PCs 1-10
PPM037808 PGS019626
(TPMI_696.42_PRS-CS)
PSS013516|
East Asian Ancestry|
17,217 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Psoriatic arthropathy AUROC: 0.83564 : 0.03999 sex, age, array, PCs 1-10
PPM037809 PGS019627
(TPMI_696.42_PRSmix+)
PSS013517|
East Asian Ancestry|
17,217 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Psoriatic arthropathy AUROC: 0.83983 : 0.03876 sex, age, array, PCs 1-10
PPM037810 PGS019628
(TPMI_696.42_SBayesR)
PSS013518|
East Asian Ancestry|
17,217 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Psoriatic arthropathy AUROC: 0.81945 : 0.0345 sex, age, array, PCs 1-10
PPM037838 PGS019656
(TPMI_714_Lassosum2)
PSS013564|
East Asian Ancestry|
19,066 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis and other inflammatory polyarthropathies AUROC: 0.75949 : 0.18539 sex, age, array, PCs 1-10
PPM037839 PGS019657
(TPMI_714_LDpred2)
PSS013563|
East Asian Ancestry|
19,066 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis and other inflammatory polyarthropathies AUROC: 0.7628 : 0.19137 sex, age, array, PCs 1-10
PPM037840 PGS019658
(TPMI_714_MegaPRS)
PSS013565|
East Asian Ancestry|
19,066 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis and other inflammatory polyarthropathies AUROC: 0.75343 : 0.1741 sex, age, array, PCs 1-10
PPM037841 PGS019659
(TPMI_714_PRS-CS)
PSS013566|
East Asian Ancestry|
19,066 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis and other inflammatory polyarthropathies AUROC: 0.76264 : 0.18871 sex, age, array, PCs 1-10
PPM037842 PGS019660
(TPMI_714_SBayesR)
PSS013567|
East Asian Ancestry|
19,066 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis and other inflammatory polyarthropathies AUROC: 0.75305 : 0.17652 sex, age, array, PCs 1-10
PPM037843 PGS019661
(TPMI_714.1_Lassosum2)
PSS013559|
East Asian Ancestry|
18,806 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis AUROC: 0.77575 : 0.1637 sex, age, array, PCs 1-10
PPM037844 PGS019662
(TPMI_714.1_LDpred2)
PSS013558|
East Asian Ancestry|
18,806 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis AUROC: 0.78037 : 0.17074 sex, age, array, PCs 1-10
PPM037845 PGS019663
(TPMI_714.1_MegaPRS)
PSS013560|
East Asian Ancestry|
18,806 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis AUROC: 0.76224 : 0.14485 sex, age, array, PCs 1-10
PPM037846 PGS019664
(TPMI_714.1_PRS-CS)
PSS013561|
East Asian Ancestry|
18,806 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis AUROC: 0.77497 : 0.16025 sex, age, array, PCs 1-10
PPM037847 PGS019665
(TPMI_714.1_SBayesR)
PSS013562|
East Asian Ancestry|
18,806 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Rheumatoid arthritis AUROC: 0.76827 : 0.15327 sex, age, array, PCs 1-10
PPM037848 PGS019666
(TPMI_715_Lassosum2)
PSS013575|
East Asian Ancestry|
18,447 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other inflammatory spondylopathies AUROC: 0.77155 : 0.19045 sex, age, array, PCs 1-10
PPM037849 PGS019667
(TPMI_715_LDpred2)
PSS013574|
East Asian Ancestry|
18,447 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other inflammatory spondylopathies AUROC: 0.77135 : 0.19831 sex, age, array, PCs 1-10
PPM037850 PGS019668
(TPMI_715_MegaPRS)
PSS013576|
East Asian Ancestry|
18,447 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other inflammatory spondylopathies AUROC: 0.75763 : 0.10413 sex, age, array, PCs 1-10
PPM037851 PGS019669
(TPMI_715_PRS-CS)
PSS013577|
East Asian Ancestry|
18,447 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other inflammatory spondylopathies AUROC: 0.78205 : 0.21691 sex, age, array, PCs 1-10
PPM037852 PGS019670
(TPMI_715_SBayesR)
PSS013578|
East Asian Ancestry|
18,447 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other inflammatory spondylopathies AUROC: 0.7758 : 0.16313 sex, age, array, PCs 1-10
PPM037853 PGS019671
(TPMI_715.2_Lassosum2)
PSS013569|
East Asian Ancestry|
18,296 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Ankylosing spondylitis AUROC: 0.86947 : 0.25284 sex, age, array, PCs 1-10
PPM037854 PGS019672
(TPMI_715.2_LDpred2)
PSS013568|
East Asian Ancestry|
18,296 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Ankylosing spondylitis AUROC: 0.86298 : 0.23372 sex, age, array, PCs 1-10
PPM037855 PGS019673
(TPMI_715.2_MegaPRS)
PSS013570|
East Asian Ancestry|
18,296 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Ankylosing spondylitis AUROC: 0.85382 : 0.13327 sex, age, array, PCs 1-10
PPM037856 PGS019674
(TPMI_715.2_PRS-CS)
PSS013571|
East Asian Ancestry|
18,296 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Ankylosing spondylitis AUROC: 0.86714 : 0.24903 sex, age, array, PCs 1-10
PPM037857 PGS019675
(TPMI_715.2_PRSmix+)
PSS013572|
East Asian Ancestry|
18,296 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Ankylosing spondylitis AUROC: 0.86288 : 0.2427 sex, age, array, PCs 1-10
PPM037858 PGS019676
(TPMI_715.2_SBayesR)
PSS013573|
East Asian Ancestry|
18,296 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Ankylosing spondylitis AUROC: 0.86099 : 0.17524 sex, age, array, PCs 1-10
PPM037859 PGS019677
(TPMI_716_Lassosum2)
PSS013595|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other arthropathies AUROC: 0.71145 : 0.20211 sex, age, array, PCs 1-10
PPM037860 PGS019678
(TPMI_716_LDpred2)
PSS013594|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other arthropathies AUROC: 0.71224 : 0.20316 sex, age, array, PCs 1-10
PPM037861 PGS019679
(TPMI_716_MegaPRS)
PSS013596|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other arthropathies AUROC: 0.71079 : 0.2011 sex, age, array, PCs 1-10
PPM037862 PGS019680
(TPMI_716_PRS-CS)
PSS013597|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other arthropathies AUROC: 0.7106 : 0.20181 sex, age, array, PCs 1-10
PPM037863 PGS019681
(TPMI_716_SBayesR)
PSS013598|
East Asian Ancestry|
18,461 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Other arthropathies AUROC: 0.71041 : 0.20075 sex, age, array, PCs 1-10
PPM037864 PGS019682
(TPMI_716.1_Lassosum2)
PSS013580|
East Asian Ancestry|
17,711 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Unspecified polyarthropathy or polyarthritis AUROC: 0.82745 : 0.09598 sex, age, array, PCs 1-10
PPM037865 PGS019683
(TPMI_716.1_LDpred2)
PSS013579|
East Asian Ancestry|
17,711 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Unspecified polyarthropathy or polyarthritis AUROC: 0.8272 : 0.09573 sex, age, array, PCs 1-10
PPM037866 PGS019684
(TPMI_716.1_MegaPRS)
PSS013581|
East Asian Ancestry|
17,711 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Unspecified polyarthropathy or polyarthritis AUROC: 0.82667 : 0.09477 sex, age, array, PCs 1-10
PPM037867 PGS019685
(TPMI_716.1_PRS-CS)
PSS013582|
East Asian Ancestry|
17,711 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Unspecified polyarthropathy or polyarthritis AUROC: 0.82659 : 0.09507 sex, age, array, PCs 1-10
PPM037868 PGS019686
(TPMI_716.1_SBayesR)
PSS013583|
East Asian Ancestry|
17,711 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Unspecified polyarthropathy or polyarthritis AUROC: 0.82705 : 0.09462 sex, age, array, PCs 1-10
PPM037869 PGS019687
(TPMI_716.8_Lassosum2)
PSS013585|
East Asian Ancestry|
17,549 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Palindromic rheumatism AUROC: 0.88197 : 0.06193 sex, age, array, PCs 1-10
PPM037870 PGS019688
(TPMI_716.8_LDpred2)
PSS013584|
East Asian Ancestry|
17,549 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Palindromic rheumatism AUROC: 0.88299 : 0.06265 sex, age, array, PCs 1-10
PPM037871 PGS019689
(TPMI_716.8_MegaPRS)
PSS013586|
East Asian Ancestry|
17,549 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Palindromic rheumatism AUROC: 0.87892 : 0.06075 sex, age, array, PCs 1-10
PPM037872 PGS019690
(TPMI_716.8_PRS-CS)
PSS013587|
East Asian Ancestry|
17,549 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Palindromic rheumatism AUROC: 0.88087 : 0.0618 sex, age, array, PCs 1-10
PPM037873 PGS019691
(TPMI_716.8_SBayesR)
PSS013588|
East Asian Ancestry|
17,549 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Palindromic rheumatism AUROC: 0.87922 : 0.06086 sex, age, array, PCs 1-10
PPM037874 PGS019692
(TPMI_716.9_Lassosum2)
PSS013590|
East Asian Ancestry|
18,443 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Arthropathy NOS AUROC: 0.70638 : 0.18177 sex, age, array, PCs 1-10
PPM037875 PGS019693
(TPMI_716.9_LDpred2)
PSS013589|
East Asian Ancestry|
18,443 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Arthropathy NOS AUROC: 0.7058 : 0.18169 sex, age, array, PCs 1-10
PPM037876 PGS019694
(TPMI_716.9_MegaPRS)
PSS013591|
East Asian Ancestry|
18,443 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Arthropathy NOS AUROC: 0.70522 : 0.18075 sex, age, array, PCs 1-10
PPM037877 PGS019695
(TPMI_716.9_PRS-CS)
PSS013592|
East Asian Ancestry|
18,443 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Arthropathy NOS AUROC: 0.7058 : 0.18102 sex, age, array, PCs 1-10
PPM037878 PGS019696
(TPMI_716.9_SBayesR)
PSS013593|
East Asian Ancestry|
18,443 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Arthropathy NOS AUROC: 0.70583 : 0.18053 sex, age, array, PCs 1-10
PPM037904 PGS019722
(TPMI_743_Lassosum2)
PSS013630|
East Asian Ancestry|
19,713 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis osteopenia and pathological fracture AUROC: 0.70063 : 0.10592 sex, age, array, PCs 1-10
PPM037905 PGS019723
(TPMI_743_LDpred2)
PSS013629|
East Asian Ancestry|
19,713 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis osteopenia and pathological fracture AUROC: 0.70305 : 0.10869 sex, age, array, PCs 1-10
PPM037906 PGS019724
(TPMI_743_MegaPRS)
PSS013631|
East Asian Ancestry|
19,713 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis osteopenia and pathological fracture AUROC: 0.70086 : 0.10624 sex, age, array, PCs 1-10
PPM037907 PGS019725
(TPMI_743_PRS-CS)
PSS013632|
East Asian Ancestry|
19,713 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis osteopenia and pathological fracture AUROC: 0.70309 : 0.10872 sex, age, array, PCs 1-10
PPM037908 PGS019726
(TPMI_743_SBayesR)
PSS013633|
East Asian Ancestry|
19,713 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis osteopenia and pathological fracture AUROC: 0.70126 : 0.1063 sex, age, array, PCs 1-10
PPM037909 PGS019727
(TPMI_743.11_Lassosum2)
PSS013625|
East Asian Ancestry|
19,445 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis NOS AUROC: 0.72863 : 0.1006 sex, age, array, PCs 1-10
PPM037910 PGS019728
(TPMI_743.11_LDpred2)
PSS013624|
East Asian Ancestry|
19,445 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis NOS AUROC: 0.73207 : 0.10412 sex, age, array, PCs 1-10
PPM037911 PGS019729
(TPMI_743.11_MegaPRS)
PSS013626|
East Asian Ancestry|
19,445 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis NOS AUROC: 0.73031 : 0.10228 sex, age, array, PCs 1-10
PPM037912 PGS019730
(TPMI_743.11_PRS-CS)
PSS013627|
East Asian Ancestry|
19,445 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis NOS AUROC: 0.73127 : 0.10329 sex, age, array, PCs 1-10
PPM037913 PGS019731
(TPMI_743.11_SBayesR)
PSS013628|
East Asian Ancestry|
19,445 individuals
PGP000835 |
Chen HH et al. Nature (2025)
Reported Trait: Osteoporosis NOS AUROC: 0.7314 : 0.1032 sex, age, array, PCs 1-10

Evaluated Samples

PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS008461 1,200 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS004183
[
  • 3 cases
  • , 6,494 controls
]
African unspecified UKB
PSS004185
[
  • 12 cases
  • , 24,893 controls
]
European non-white British ancestry UKB
PSS004186
[
  • 2 cases
  • , 7,829 controls
]
South Asian UKB
PSS004187
[
  • 30 cases
  • , 67,395 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004188
[
  • 5 cases
  • , 6,492 controls
]
African unspecified UKB
PSS008162 6,171 individuals South Asian India (South Asia) UKB
PSS004190
[
  • 32 cases
  • , 24,873 controls
]
European non-white British ancestry UKB
PSS004191
[
  • 18 cases
  • , 7,813 controls
]
South Asian UKB
PSS004192
[
  • 127 cases
  • , 67,298 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004193
[
  • 122 cases
  • , 6,375 controls
]
African unspecified UKB
PSS004706
[
  • 2 cases
  • , 6,495 controls
]
African unspecified UKB
PSS004707
[
  • 2 cases
  • , 1,702 controls
]
East Asian UKB
PSS004708
[
  • 81 cases
  • , 24,824 controls
]
European non-white British ancestry UKB
PSS004709
[
  • 21 cases
  • , 7,810 controls
]
South Asian UKB
PSS004710
[
  • 231 cases
  • , 67,194 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004194
[
  • 19 cases
  • , 1,685 controls
]
East Asian UKB
PSS004195
[
  • 409 cases
  • , 24,496 controls
]
European non-white British ancestry UKB
PSS004196
[
  • 197 cases
  • , 7,634 controls
]
South Asian UKB
PSS004197
[
  • 1,343 cases
  • , 66,082 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS008684 6,366 individuals European Italy (South Europe) UKB
PSS008687 6,660 individuals European Italy (South Europe) UKB
PSS008688 6,657 individuals European Italy (South Europe) UKB
PSS004208
[
  • 85 cases
  • , 6,412 controls
]
African unspecified UKB
PSS004209
[
  • 16 cases
  • , 1,688 controls
]
East Asian UKB
PSS004210
[
  • 779 cases
  • , 24,126 controls
]
European non-white British ancestry UKB
PSS004211
[
  • 74 cases
  • , 7,757 controls
]
South Asian UKB
PSS004212
[
  • 2,783 cases
  • , 64,642 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004213
[
  • 443 cases
  • , 6,054 controls
]
African unspecified UKB
PSS004214
[
  • 56 cases
  • , 1,648 controls
]
East Asian UKB
PSS004215
[
  • 1,333 cases
  • , 23,572 controls
]
European non-white British ancestry UKB
PSS004216
[
  • 684 cases
  • , 7,147 controls
]
South Asian UKB
PSS004217
[
  • 4,861 cases
  • , 62,564 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS013591 716,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M25.8
[
  • 1,055 cases
  • , 17,388 controls
]
,
46.77 % Male samples
East Asian
(Han Chinese)
TPMI
PSS004228
[
  • 5 cases
  • , 6,492 controls
]
African unspecified UKB
PSS004229
[
  • 2 cases
  • , 1,702 controls
]
East Asian UKB
PSS004230
[
  • 80 cases
  • , 24,825 controls
]
European non-white British ancestry UKB
PSS004231
[
  • 15 cases
  • , 7,816 controls
]
South Asian UKB
PSS004232
[
  • 278 cases
  • , 67,147 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004233
[
  • 234 cases
  • , 6,263 controls
]
African unspecified UKB
PSS004234
[
  • 37 cases
  • , 1,667 controls
]
East Asian UKB
PSS004235
[
  • 1,073 cases
  • , 23,832 controls
]
European non-white British ancestry UKB
PSS004236
[
  • 344 cases
  • , 7,487 controls
]
South Asian UKB
PSS004237
[
  • 3,084 cases
  • , 64,341 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS011222
[
  • 2,384 cases
  • , 196,890 controls
]
European EB
PSS009889 Radiographic hip and/or knee-OA was defined in all five cohorts by a KL score ≥ 2 for one or both joints.In the CHECK cohort, clinical OA was defined as clinically relevant hip or knee osteoarthritis by a group of 36 GPs and secondary care physicians by manually evaluating the study records over the 5-10 years of follow-up 1,002 individuals,
21.0 % Male samples
Mean = 55.9 years
Sd = 5.2 years
European NR CHECK
PSS009890 Radiographic hip and/or knee-OA was defined in all five cohorts by a KL score ≥ 2 for one or both joints.Clinical OA in the PROOF cohort was defined based on the American College of Rheumatology (ACR) definition [26], which is defined based on knee pain on most days of the last month plus at least 3 of the following clinical findings: age > 50 years, stiffness < 30 minutes, crepitus, bony tenderness, bony enlargement, and no palpable warmth. Prevalent cases were defined at baseline. 407 individuals,
0.0 % Male samples
Mean = 55.8 years
Sd = 3.2 years
European NR PROOF
PSS009891 Radiographic hip and/or knee-OA was defined in all five cohorts by a KL score ≥ 2 for one or both joints.Clinical OA in Rotterdam Study was defined as reported pain in the last month and a KL score ≥ 2 in that hip or knee joint and the control group was defined as containing all participants who had not been diagnosed with radiographic OA by the end of follow-up time. 14,926 individuals European RS
PSS013514 696.0,L40.5
[
  • 167 cases
  • , 17,050 controls
]
,
48.3 % Male samples
East Asian
(Han Chinese)
TPMI
PSS004243
[
  • 85 cases
  • , 6,412 controls
]
African unspecified UKB
PSS004244
[
  • 30 cases
  • , 1,674 controls
]
East Asian UKB
PSS004245
[
  • 1,020 cases
  • , 23,885 controls
]
European non-white British ancestry UKB
PSS000429 JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children.
[
  • 66 cases
  • , 2,954 controls
]
,
51.46 % Male samples
European CHOP
PSS000430 JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children.
[
  • 203 cases
  • , 2,954 controls
]
,
49.19 % Male samples
European CHOP
PSS000431 JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children.
[
  • 135 cases
  • , 2,954 controls
]
,
50.11 % Male samples
European CHOP
PSS000432 Diagnosis of JIA by a paediatric rheumatologist.
[
  • 16 cases
  • , 578 controls
]
,
58.59 % Male samples
European CLARITY Cohort description (PMID): 23153063
PSS000433 Diagnosis of JIA by a paediatric rheumatologist.
[
  • 159 cases
  • , 578 controls
]
,
51.15 % Male samples
European CLARITY Cohort description (PMID): 23153063
PSS000434 Diagnosis of JIA by a paediatric rheumatologist.
[
  • 75 cases
  • , 578 controls
]
,
54.82 % Male samples
European CLARITY Cohort description (PMID): 23153063
PSS004246
[
  • 205 cases
  • , 7,626 controls
]
South Asian UKB
PSS004247
[
  • 2,326 cases
  • , 65,099 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS011233 RHEUMA_SEROPOS_OTH, ICD10: M05[8-9], ICD9: 7140A
[
  • 9,332 cases
  • , 379,558 controls
]
European FinnGen
PSS008680 6,241 individuals European Italy (South Europe) UKB
PSS008234 5,728 individuals South Asian India (South Asia) UKB
PSS008235 5,671 individuals South Asian India (South Asia) UKB
PSS011246
[
  • 60 cases
  • , 43,997 controls
]
South Asian G&H
PSS008238 5,964 individuals South Asian India (South Asia) UKB
PSS008681 6,216 individuals European Italy (South Europe) UKB
PSS009586 Severe progressive group as patients with the top quartile of SHS (more than 35 points) and the non-severe progressive group as the remaining patients. 740 individuals,
14.4 % Male samples
Mean = 48.5 years
Sd = 12.4 years
East Asian
(Japanese)
IORRA
PSS008241 6,331 individuals South Asian India (South Asia) UKB
PSS008242 6,327 individuals South Asian India (South Asia) UKB
PSS000179 JIA diagnosis was made according to International League of Associations for Rheumatology standards (PMID:14760812) from EHR. Control subjects were unrelated and disease-free children.
[
  • 559 cases
  • , 2,954 controls
]
,
47.5 % Male samples
European CHOP
PSS000180 Diagnosis of JIA by a paediatric rheumatologist.
[
  • 362 cases
  • , 578 controls
]
,
48.9 % Male samples
European CLARITY Cohort description (PMID): 23153063
PSS011922
[
  • 3,074 cases
  • , 55,537 controls
]
East Asian
(Korean)
HEXA
PSS011262
[
  • 1,139 cases
  • , 65,726 controls
]
European HUNT
PSS013558 714.0, 714.1, 714.2, 714.81,M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.8, M06.9
[
  • 778 cases
  • , 18,028 controls
]
,
46.08 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013559 714.0, 714.1, 714.2, 714.81,M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.8, M06.9
[
  • 778 cases
  • , 18,028 controls
]
,
46.08 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013560 714.0, 714.1, 714.2, 714.81,M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.8, M06.9
[
  • 778 cases
  • , 18,028 controls
]
,
46.08 % Male samples
East Asian
(Han Chinese)
TPMI
PSS009280 19,539 individuals European UK (+ Ireland) UKB
PSS013561 714.0, 714.1, 714.2, 714.81,M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.8, M06.9
[
  • 778 cases
  • , 18,028 controls
]
,
46.08 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013563 714,M04.8, M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.4, M06.8, M06.9, M08, M12.0, M13.0
[
  • 1,038 cases
  • , 18,028 controls
]
,
45.78 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013564 714,M04.8, M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.4, M06.8, M06.9, M08, M12.0, M13.0
[
  • 1,038 cases
  • , 18,028 controls
]
,
45.78 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013565 714,M04.8, M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.4, M06.8, M06.9, M08, M12.0, M13.0
[
  • 1,038 cases
  • , 18,028 controls
]
,
45.78 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013566 714,M04.8, M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.4, M06.8, M06.9, M08, M12.0, M13.0
[
  • 1,038 cases
  • , 18,028 controls
]
,
45.78 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013567 714,M04.8, M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.4, M06.8, M06.9, M08, M12.0, M13.0
[
  • 1,038 cases
  • , 18,028 controls
]
,
45.78 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013562 714.0, 714.1, 714.2, 714.81,M05.0, M05.1, M05.2, M05.30, M05.31, M05.32, M05.33, M05.34, M05.35, M05.36, M05.37, M05.39, M05.40, M05.41, M05.42, M05.43, M05.44, M05.45, M05.46, M05.47, M05.49, M05.50, M05.51, M05.52, M05.53, M05.54, M05.55, M05.56, M05.57, M05.59, M05.6, M05.7, M05.8, M05.9, M06.0, M06.1, M06.20, M06.21, M06.22, M06.23, M06.24, M06.25, M06.26, M06.27, M06.28, M06.29, M06.3, M06.8, M06.9
[
  • 778 cases
  • , 18,028 controls
]
,
46.08 % Male samples
East Asian
(Han Chinese)
TPMI
PSS011275
[
  • 205 cases
  • , 90,069 controls
]
European UKB
PSS013569 720.0,M08.1, M45
[
  • 268 cases
  • , 18,028 controls
]
,
47.47 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013568 720.0,M08.1, M45
[
  • 268 cases
  • , 18,028 controls
]
,
47.47 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013570 720.0,M08.1, M45
[
  • 268 cases
  • , 18,028 controls
]
,
47.47 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013571 720.0,M08.1, M45
[
  • 268 cases
  • , 18,028 controls
]
,
47.47 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013574 720,M08.1, M45, M46, M49
[
  • 419 cases
  • , 18,028 controls
]
,
47.42 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013575 720,M08.1, M45, M46, M49
[
  • 419 cases
  • , 18,028 controls
]
,
47.42 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013576 720,M08.1, M45, M46, M49
[
  • 419 cases
  • , 18,028 controls
]
,
47.42 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013577 720,M08.1, M45, M46, M49
[
  • 419 cases
  • , 18,028 controls
]
,
47.42 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013578 720,M08.1, M45, M46, M49
[
  • 419 cases
  • , 18,028 controls
]
,
47.42 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013572 720.0,M08.1, M45
[
  • 268 cases
  • , 18,028 controls
]
,
47.47 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013573 720.0,M08.1, M45
[
  • 268 cases
  • , 18,028 controls
]
,
47.47 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013580 716.5,
[
  • 323 cases
  • , 17,388 controls
]
,
47.04 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013579 716.5,
[
  • 323 cases
  • , 17,388 controls
]
,
47.04 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013581 716.5,
[
  • 323 cases
  • , 17,388 controls
]
,
47.04 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013582 716.5,
[
  • 323 cases
  • , 17,388 controls
]
,
47.04 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013583 716.5,
[
  • 323 cases
  • , 17,388 controls
]
,
47.04 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013585 719.3,M12.3, M12.4
[
  • 161 cases
  • , 17,388 controls
]
,
47.31 % Male samples
East Asian
(Han Chinese)
TPMI
PSS011465 9,462 individuals European AllofUs
PSS013584 719.3,M12.3, M12.4
[
  • 161 cases
  • , 17,388 controls
]
,
47.31 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013586 719.3,M12.3, M12.4
[
  • 161 cases
  • , 17,388 controls
]
,
47.31 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013587 719.3,M12.3, M12.4
[
  • 161 cases
  • , 17,388 controls
]
,
47.31 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013588 719.3,M12.3, M12.4
[
  • 161 cases
  • , 17,388 controls
]
,
47.31 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013590 716,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M25.8
[
  • 1,055 cases
  • , 17,388 controls
]
,
46.77 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013589 716,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M25.8
[
  • 1,055 cases
  • , 17,388 controls
]
,
46.77 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013594 716, 719.3,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M13.1, M13.8, M25.8
[
  • 1,073 cases
  • , 17,388 controls
]
,
46.73 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013595 716, 719.3,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M13.1, M13.8, M25.8
[
  • 1,073 cases
  • , 17,388 controls
]
,
46.73 % Male samples
East Asian
(Han Chinese)
TPMI
PSS008462 1,199 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS011474 8,837 individuals South Asian G&H
PSS013596 716, 719.3,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M13.1, M13.8, M25.8
[
  • 1,073 cases
  • , 17,388 controls
]
,
46.73 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013597 716, 719.3,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M13.1, M13.8, M25.8
[
  • 1,073 cases
  • , 17,388 controls
]
,
46.73 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013598 716, 719.3,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M13.1, M13.8, M25.8
[
  • 1,073 cases
  • , 17,388 controls
]
,
46.73 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013592 716,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M25.8
[
  • 1,055 cases
  • , 17,388 controls
]
,
46.77 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013593 716,M02.0, M02.2, M07.60, M07.61, M07.62, M07.63, M07.64, M07.65, M07.66, M07.67, M07.68, M07.69, M12, M25.8
[
  • 1,055 cases
  • , 17,388 controls
]
,
46.77 % Male samples
East Asian
(Han Chinese)
TPMI
PSS009927
[
  • 969 cases
  • , 6,491 controls
]
European, East Asian, African unspecified, South Asian, Greater Middle Eastern (Middle Eastern, North African or Persian) BBJ Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap
PSS000312 Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 8.0 years
[
  • 30 cases
  • , 215 controls
]
,
32.0 % Male samples
European PHB
PSS000313 Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 7.0 years
[
  • 22 cases
  • , 221 controls
]
,
32.0 % Male samples
European PHB
PSS000314 Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 8.0 years
[
  • 90 cases
  • , 155 controls
]
,
32.0 % Male samples
European PHB
PSS000315 Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 7.0 years
[
  • 115 cases
  • , 128 controls
]
,
32.0 % Male samples
European PHB
PSS000316 Setting II: Based on ICD codes and review of medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 8.0 years
[
  • 31 cases
  • , 214 controls
]
,
32.0 % Male samples
European PHB
PSS000317 Setting III: Based on ICD codes and final diagnosis in medical records from Partners HealthCare Biobank; controls = other non-matching arthritis diseases Median = 7.0 years
[
  • 8 cases
  • , 235 controls
]
,
32.0 % Male samples
European PHB
PSS004326
[
  • 69 cases
  • , 6,428 controls
]
African unspecified UKB
PSS004327
[
  • 11 cases
  • , 1,693 controls
]
East Asian UKB
PSS004328
[
  • 434 cases
  • , 24,471 controls
]
European non-white British ancestry UKB
PSS000321 Setting I: Based on ICD codes and expert opinion (ACR2010 criteria), in eMERGE network EMR database from Stanaway 2018; controls = other non-matching arthritis diseases Median = 16.0 years
[
  • 52 cases
  • , 1,159 controls
]
,
43.0 % Male samples
European, African unspecified, Asian unspecified, NR Primarily European, African and Asian ancestry eMERGE
PSS000322 Setting I: Based on ICD codes and expert opinion (ACR2010 criteria), in eMERGE network EMR database from Stanaway 2018; controls = other non-matching arthritis diseases Median = 16.0 years
[
  • 574 cases
  • , 637 controls
]
,
43.0 % Male samples
European, African unspecified, Asian unspecified, NR Primarily European, African and Asian ancestry eMERGE
PSS000323 Setting I: Based on ICD codes and expert opinion (ACR2010 criteria), in eMERGE network EMR database from Stanaway 2018; controls = other non-matching arthritis diseases Median = 16.0 years
[
  • 65 cases
  • , 1,146 controls
]
,
43.0 % Male samples
European, African unspecified, Asian unspecified, NR Primarily European, African and Asian ancestry eMERGE
PSS004329
[
  • 110 cases
  • , 7,721 controls
]
South Asian UKB
PSS004330
[
  • 1,236 cases
  • , 66,189 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS007799 2,277 individuals African American or Afro-Caribbean Carribean UKB
PSS007802 2,358 individuals African American or Afro-Caribbean Carribean UKB
PSS007805 2,484 individuals African American or Afro-Caribbean Carribean UKB
PSS007806 2,483 individuals African American or Afro-Caribbean Carribean UKB
PSS009936 1,422 individuals European ASPREE
PSS009935 1,257 individuals European ASPREE
PSS013515 696.0,L40.5
[
  • 167 cases
  • , 17,050 controls
]
,
48.3 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013516 696.0,L40.5
[
  • 167 cases
  • , 17,050 controls
]
,
48.3 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013625 733.00,M81
[
  • 813 cases
  • , 18,632 controls
]
,
46.43 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013629 733, V13.51, V13.52, V54.2,M48.4, M48.5, M80.0, M80.8, M81, M84.3, M84.4, M84.5, M84.6, M84.7, M85.9, M89.9, Z87.310, Z87.311, Z87.312
[
  • 1,081 cases
  • , 18,632 controls
]
,
46.23 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013630 733, V13.51, V13.52, V54.2,M48.4, M48.5, M80.0, M80.8, M81, M84.3, M84.4, M84.5, M84.6, M84.7, M85.9, M89.9, Z87.310, Z87.311, Z87.312
[
  • 1,081 cases
  • , 18,632 controls
]
,
46.23 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013631 733, V13.51, V13.52, V54.2,M48.4, M48.5, M80.0, M80.8, M81, M84.3, M84.4, M84.5, M84.6, M84.7, M85.9, M89.9, Z87.310, Z87.311, Z87.312
[
  • 1,081 cases
  • , 18,632 controls
]
,
46.23 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013517 696.0,L40.5
[
  • 167 cases
  • , 17,050 controls
]
,
48.3 % Male samples
East Asian
(Han Chinese)
TPMI
PSS009352 18,393 individuals European UK (+ Ireland) UKB
PSS009353 18,262 individuals European UK (+ Ireland) UKB
PSS013632 733, V13.51, V13.52, V54.2,M48.4, M48.5, M80.0, M80.8, M81, M84.3, M84.4, M84.5, M84.6, M84.7, M85.9, M89.9, Z87.310, Z87.311, Z87.312
[
  • 1,081 cases
  • , 18,632 controls
]
,
46.23 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013633 733, V13.51, V13.52, V54.2,M48.4, M48.5, M80.0, M80.8, M81, M84.3, M84.4, M84.5, M84.6, M84.7, M85.9, M89.9, Z87.310, Z87.311, Z87.312
[
  • 1,081 cases
  • , 18,632 controls
]
,
46.23 % Male samples
East Asian
(Han Chinese)
TPMI
PSS009356 18,953 individuals European UK (+ Ireland) UKB
PSS013518 696.0,L40.5
[
  • 167 cases
  • , 17,050 controls
]
,
48.3 % Male samples
East Asian
(Han Chinese)
TPMI
PSS009359 20,000 individuals European UK (+ Ireland) UKB
PSS009360 19,982 individuals European UK (+ Ireland) UKB
PSS000490 Cases included physician-confirmed psoriatic arthritis (PsA). Controls inclded individuals with psoriasis with no history of joint symptoms (psoriasis only - PsO).
[
  • 140 cases
  • , 403 controls
]
NR NR
PSS004369
[
  • 92 cases
  • , 6,405 controls
]
African unspecified UKB
PSS004370
[
  • 24 cases
  • , 1,680 controls
]
East Asian UKB
PSS004371
[
  • 932 cases
  • , 23,973 controls
]
European non-white British ancestry UKB
PSS004372
[
  • 195 cases
  • , 7,636 controls
]
South Asian UKB
PSS004373
[
  • 2,151 cases
  • , 65,274 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS013624 733.00,M81
[
  • 813 cases
  • , 18,632 controls
]
,
46.43 % Male samples
East Asian
(Han Chinese)
TPMI
PSS009939 39,444 individuals European
(Finnish)
FinnGen
PSS013626 733.00,M81
[
  • 813 cases
  • , 18,632 controls
]
,
46.43 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013627 733.00,M81
[
  • 813 cases
  • , 18,632 controls
]
,
46.43 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013628 733.00,M81
[
  • 813 cases
  • , 18,632 controls
]
,
46.43 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013172 473, 784.91,J32, R09.82
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013173 473, 784.91,J32, R09.82
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013174 473, 784.91,J32, R09.82
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013175 473, 784.91,J32, R09.82
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013176 473, 784.91,J32, R09.82
[
  • 634 cases
  • , 15,426 controls
]
,
46.53 % Male samples
East Asian
(Han Chinese)
TPMI
PSS008384 1,178 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008903 3,634 individuals African unspecified Nigeria (West Africa) UKB
PSS008906 3,779 individuals African unspecified Nigeria (West Africa) UKB
PSS008909 3,924 individuals African unspecified Nigeria (West Africa) UKB
PSS008910 3,923 individuals African unspecified Nigeria (West Africa) UKB
PSS013202 523.0, 523.1, 523.2,K05.0, K05.1, K06.0
[
  • 472 cases
  • , 16,622 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013203 523.0, 523.1, 523.2,K05.0, K05.1, K06.0
[
  • 472 cases
  • , 16,622 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013204 523.0, 523.1, 523.2,K05.0, K05.1, K06.0
[
  • 472 cases
  • , 16,622 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013205 523.0, 523.1, 523.2,K05.0, K05.1, K06.0
[
  • 472 cases
  • , 16,622 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013206 523.0, 523.1, 523.2,K05.0, K05.1, K06.0
[
  • 472 cases
  • , 16,622 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013207 522.4, 522.6, 523.3, 523.4, 523.5,K04.4, K04.5, K05.2, K05.3, K05.4
[
  • 1,559 cases
  • , 16,622 controls
]
,
46.09 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013208 522.4, 522.6, 523.3, 523.4, 523.5,K04.4, K04.5, K05.2, K05.3, K05.4
[
  • 1,559 cases
  • , 16,622 controls
]
,
46.09 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013209 522.4, 522.6, 523.3, 523.4, 523.5,K04.4, K04.5, K05.2, K05.3, K05.4
[
  • 1,559 cases
  • , 16,622 controls
]
,
46.09 % Male samples
East Asian
(Han Chinese)
TPMI
PSS010115
[
  • 185 cases
  • , 1,112 controls
]
East Asian
(Taiwanese)
NR TPMI
PSS013210 522.4, 522.6, 523.3, 523.4, 523.5,K04.4, K04.5, K05.2, K05.3, K05.4
[
  • 1,559 cases
  • , 16,622 controls
]
,
46.09 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013212 522.4, 522.6, 523,K03.6, K04.4, K04.5, K05.0, K05.1, K05.2, K05.3, K05.4, K05.5, K05.6, K06.0, K06.1, K06.2, K06.8, K06.9
[
  • 1,839 cases
  • , 16,622 controls
]
,
46.14 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013213 522.4, 522.6, 523,K03.6, K04.4, K04.5, K05.0, K05.1, K05.2, K05.3, K05.4, K05.5, K05.6, K06.0, K06.1, K06.2, K06.8, K06.9
[
  • 1,839 cases
  • , 16,622 controls
]
,
46.14 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013214 522.4, 522.6, 523,K03.6, K04.4, K04.5, K05.0, K05.1, K05.2, K05.3, K05.4, K05.5, K05.6, K06.0, K06.1, K06.2, K06.8, K06.9
[
  • 1,839 cases
  • , 16,622 controls
]
,
46.14 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013215 522.4, 522.6, 523,K03.6, K04.4, K04.5, K05.0, K05.1, K05.2, K05.3, K05.4, K05.5, K05.6, K06.0, K06.1, K06.2, K06.8, K06.9
[
  • 1,839 cases
  • , 16,622 controls
]
,
46.14 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013216 522.4, 522.6, 523,K03.6, K04.4, K04.5, K05.0, K05.1, K05.2, K05.3, K05.4, K05.5, K05.6, K06.0, K06.1, K06.2, K06.8, K06.9
[
  • 1,839 cases
  • , 16,622 controls
]
,
46.14 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013211 522.4, 522.6, 523.3, 523.4, 523.5,K04.4, K04.5, K05.2, K05.3, K05.4
[
  • 1,559 cases
  • , 16,622 controls
]
,
46.09 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013218 524.6,M26.6
[
  • 162 cases
  • , 16,622 controls
]
,
45.45 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013217 524.6,M26.6
[
  • 162 cases
  • , 16,622 controls
]
,
45.45 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013219 524.6,M26.6
[
  • 162 cases
  • , 16,622 controls
]
,
45.45 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013220 524.6,M26.6
[
  • 162 cases
  • , 16,622 controls
]
,
45.45 % Male samples
East Asian
(Han Chinese)
TPMI
PSS013221 524.6,M26.6
[
  • 162 cases
  • , 16,622 controls
]
,
45.45 % Male samples
East Asian
(Han Chinese)
TPMI
PSS011342
[
  • 1,563 cases
  • , 65,865 controls
]
,
46.0 % Male samples
European
(White British)
UKB
PSS004461
[
  • 305 cases
  • , 6,192 controls
]
African unspecified UKB
PSS004462
[
  • 56 cases
  • , 1,648 controls
]
East Asian UKB
PSS004463
[
  • 1,688 cases
  • , 23,217 controls
]
European non-white British ancestry UKB
PSS004464
[
  • 425 cases
  • , 7,406 controls
]
South Asian UKB
PSS004465
[
  • 6,097 cases
  • , 61,328 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS009928
[
  • 624 cases
  • , 680 controls
]
African unspecified, South Asian, Greater Middle Eastern (Middle Eastern, North African or Persian) NR Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap
PSS009929
[
  • 1,378 cases
  • , 20,326 controls
]
East Asian BBJ Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap
PSS009930
[
  • 894 cases
  • , 2,993 controls
]
European NR Average Cohort Size. Overlaps GWAS Cohorts; however performance metrics are derived using a leave-one-cohort-out cross-validation to minimize overlap
PSS012731 274, 712,M10, M11.00, M11.01, M11.02, M11.03, M11.04, M11.05, M11.06, M11.07, M11.08, M11.09, M11.1, M11.2, M11.8, M11.9, M1A
[
  • 1,862 cases
  • , 17,819 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS012730 274, 712,M10, M11.00, M11.01, M11.02, M11.03, M11.04, M11.05, M11.06, M11.07, M11.08, M11.09, M11.1, M11.2, M11.8, M11.9, M1A
[
  • 1,862 cases
  • , 17,819 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS012732 274, 712,M10, M11.00, M11.01, M11.02, M11.03, M11.04, M11.05, M11.06, M11.07, M11.08, M11.09, M11.1, M11.2, M11.8, M11.9, M1A
[
  • 1,862 cases
  • , 17,819 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS012733 274, 712,M10, M11.00, M11.01, M11.02, M11.03, M11.04, M11.05, M11.06, M11.07, M11.08, M11.09, M11.1, M11.2, M11.8, M11.9, M1A
[
  • 1,862 cases
  • , 17,819 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS008454 1,128 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS008455 1,124 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS012734 274, 712,M10, M11.00, M11.01, M11.02, M11.03, M11.04, M11.05, M11.06, M11.07, M11.08, M11.09, M11.1, M11.2, M11.8, M11.9, M1A
[
  • 1,862 cases
  • , 17,819 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS012735 274, 712,M10, M11.00, M11.01, M11.02, M11.03, M11.04, M11.05, M11.06, M11.07, M11.08, M11.09, M11.1, M11.2, M11.8, M11.9, M1A
[
  • 1,862 cases
  • , 17,819 controls
]
,
45.75 % Male samples
East Asian
(Han Chinese)
TPMI
PSS008458 1,137 individuals Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB
PSS007949 1,787 individuals East Asian China (East Asia) UKB
PSS004486
[
  • 5 cases
  • , 6,492 controls
]
African unspecified UKB
PSS004487
[
  • 2 cases
  • , 1,702 controls
]
East Asian UKB
PSS004488
[
  • 79 cases
  • , 24,826 controls
]
European non-white British ancestry UKB
PSS004489
[
  • 14 cases
  • , 7,817 controls
]
South Asian UKB
PSS004490
[
  • 268 cases
  • , 67,157 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS004491
[
  • 118 cases
  • , 6,379 controls
]
African unspecified UKB
PSS004492
[
  • 18 cases
  • , 1,686 controls
]
East Asian UKB
PSS004493
[
  • 399 cases
  • , 24,506 controls
]
European non-white British ancestry UKB
PSS004494
[
  • 194 cases
  • , 7,637 controls
]
South Asian UKB
PSS004495
[
  • 1,301 cases
  • , 66,124 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS011363 ICD10: M05, M06 Median = 8.1 years
[
  • 2,034 cases
  • , 340,939 controls
]
,
46.58 % Male samples
Mean = 57.0 years
Sd = 7.9 years
European UKB
PSS011364 56,192 individuals European UKB
PSS012319 163,987 individuals,
45.1 % Male samples
Mean = 55.5 years
Sd = 7.9 years
European UKB
PSS011587
[
  • 21,639 cases
  • , 178,229 controls
]
European EB
PSS011588
[
  • 22,634 cases
  • , 389,456 controls
]
European FinnGen
PSS011589
[
  • 96 cases
  • , 44,092 controls
]
European G&H
PSS011590
[
  • 516 cases
  • , 6,502 controls
]
European GS:SFHS
PSS011591
[
  • 839 cases
  • , 28,588 controls
]
European GEL
PSS011592
[
  • 4,219 cases
  • , 65,496 controls
]
European HUNT
PSS011593
[
  • 5,536 cases
  • , 31,488 controls
]
European MGBB
PSS011594
[
  • 38,047 cases
  • , 161,821 controls
]
European EB
PSS011595
[
  • 46,914 cases
  • , 365,176 controls
]
European FinnGen
PSS011596
[
  • 1,053 cases
  • , 43,135 controls
]
European G&H
PSS011597
[
  • 538 cases
  • , 6,480 controls
]
European GS:SFHS
PSS011598
[
  • 1,600 cases
  • , 27,827 controls
]
European GEL
PSS011599
[
  • 5,041 cases
  • , 64,674 controls
]
European HUNT
PSS011600
[
  • 8,184 cases
  • , 29,061 controls
]
European MGBB
PSS013513 696.0,L40.5
[
  • 167 cases
  • , 17,050 controls
]
,
48.3 % Male samples
East Asian
(Han Chinese)
TPMI
PSS008014 1,754 individuals East Asian China (East Asia) UKB
PSS008017 1,759 individuals East Asian China (East Asia) UKB
PSS008019 1,810 individuals East Asian China (East Asia) UKB
PSS008020 1,808 individuals East Asian China (East Asia) UKB
PSS011630
[
  • 58 cases
  • , 44,130 controls
]
European G&H
PSS011631
[
  • 18 cases
  • , 7,000 controls
]
European GS:SFHS
PSS011632
[
  • 71 cases
  • , 29,356 controls
]
European GEL
PSS011633
[
  • 1,072 cases
  • , 68,643 controls
]
European HUNT
PSS011634
[
  • 384 cases
  • , 37,602 controls
]
European MGBB
PSS011635
[
  • 994 cases
  • , 446,338 controls
]
European UKB
PSS011629
[
  • 9,610 cases
  • , 402,480 controls
]
European FinnGen
PSS011628
[
  • 2,348 cases
  • , 197,520 controls
]
European EB
PSS009054 4,052 individuals European Poland (NE Europe) UKB
PSS004627
[
  • 407 cases
  • , 6,090 controls
]
African unspecified UKB
PSS004628
[
  • 36 cases
  • , 1,668 controls
]
East Asian UKB
PSS004629
[
  • 1,244 cases
  • , 23,661 controls
]
European non-white British ancestry UKB
PSS004630
[
  • 538 cases
  • , 7,293 controls
]
South Asian UKB
PSS004631
[
  • 4,088 cases
  • , 63,337 controls
]
European white British ancestry UKB Testing cohort (heldout set)
PSS008608 6,489 individuals European Italy (South Europe) UKB
PSS009126 3,878 individuals European Poland (NE Europe) UKB
PSS009127 3,854 individuals European Poland (NE Europe) UKB
PSS009130 3,909 individuals European Poland (NE Europe) UKB
PSS009133 4,136 individuals European Poland (NE Europe) UKB
PSS009134 4,130 individuals European Poland (NE Europe) UKB